[Hub]/) : Traits : Impedance of arm (left) : ← →

chr20:31,884,069-35,298,668

Best TWAS P=3.87e-14 · Best GWAS P=1.37e-12 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Artery Aorta	GGT7	0.06	0.00	enet	7	0.02	1.9e-02	5.6	-7.6	3.9e-14	-0.38	0.10	0.60	TRUE
32	ROSMAP	Brain Pre-frontal Cortex	RALY	0.09	0.16	lasso	7	0.15	2.7e-18	6.7	6.6	5.4e-11	0.83	0.14	0.86	TRUE
26	GTEx	Thyroid	TP53INP2	0.09	0.05	lasso	7	0.04	3.7e-04	5.5	-5.9	3.0e-09	-0.10	0.09	0.90	TRUE
17	GTEx	Cells Transformed fibroblasts	EDEM2	0.08	0.02	lasso	5	0.03	1.8e-03	-5.3	5.8	6.7e-09	0.22	0.37	0.25	TRUE
11	GTEx	Brain Hypothalamus	CEP250	0.18	-0.01	lasso	9	0.00	3.4e-01	-4.4	5.7	1.4e-08	0.06	0.11	0.15	TRUE
25	GTEx	Testis	LINC00657	0.08	0.05	enet	15	0.05	3.0e-03	-5.0	5.4	5.1e-08	0.04	0.64	0.03	TRUE
18	GTEx	Cells Transformed fibroblasts	TRPC4AP	0.06	0.01	lasso	2	0.01	4.2e-02	3.4	5.4	8.2e-08	0.15	0.12	0.35	TRUE
8	GTEx	Brain Cerebellar Hemisphere	MYH7B	0.18	0.10	lasso	5	0.08	3.7e-03	-5.3	-5.2	2.3e-07	-0.32	0.39	0.22	TRUE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCOA6	0.04	0.02	blup	65	0.04	6.1e-05	5.5	6.6	5.1e-11	0.22	0.02	0.95	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	RALY	0.05	0.04	blup	53	0.05	1.6e-05	6.5	-6.5	1.1e-10	-0.94	0.03	0.96	FALSE
13	GTEx	Breast Mammary Tissue	ITCH	0.09	0.04	enet	28	0.09	2.5e-05	-4.2	6.4	1.9e-10	0.74	0.21	0.76	FALSE
27	GTEx	Thyroid	MYH7B	0.06	0.03	enet	15	0.06	3.6e-05	-5.0	-6.1	1.1e-09	-0.37	0.70	0.19	FALSE
2	CommonMind	Brain Pre-frontal Cortex	EDEM2	0.09	0.09	enet	12	0.09	5.8e-11	-4.4	6.1	1.2e-09	0.27	0.96	0.04	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	NCOA6	0.11	0.06	enet	15	0.06	3.9e-03	-5.0	5.8	5.7e-09	0.44	0.20	0.24	FALSE
3	GTEx	Adrenal Gland	NCOA6	0.10	0.08	lasso	14	0.05	7.7e-03	5.1	5.7	1.3e-08	0.03	0.18	0.38	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	ITCH	0.11	0.03	lasso	4	0.04	9.9e-03	5.5	5.7	1.3e-08	0.13	0.33	0.06	FALSE
34	YFS	Blood	TP53INP2	0.02	0.02	lasso	15	0.01	1.3e-05	5.5	-5.7	1.5e-08	-0.09	0.13	0.86	FALSE
4	GTEx	Artery Aorta	MYH7B	0.22	0.08	lasso	6	0.09	1.3e-05	-5.3	-5.7	1.6e-08	-0.23	0.50	0.48	FALSE
12	GTEx	Brain Nucleus accumbens basal ganglia	EDEM2	0.17	0.00	lasso	4	0.00	2.7e-01	-4.9	5.6	1.8e-08	0.32	0.10	0.15	FALSE
24	GTEx	Stomach	MAP1LC3A	0.10	0.04	enet	10	0.05	1.3e-03	3.9	-5.6	2.0e-08	-0.51	0.26	0.27	FALSE
9	GTEx	Brain Cerebellum	MYH7B	0.26	0.30	lasso	4	0.26	2.2e-08	-5.3	-5.5	3.2e-08	-0.33	0.46	0.52	FALSE
37	The Cancer Genome Atlas	Colon Adenocarcinoma	NCOA6	0.06	0.03	lasso	1	0.02	2.0e-02	5.5	5.5	3.5e-08	0.08	0.02	0.79	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	PHF20	0.30	-0.01	enet	13	0.04	2.3e-02	-1.7	5.5	3.6e-08	0.12	0.06	0.05	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	SPAG4	0.05	0.04	enet	8	0.04	5.7e-06	-4.4	5.5	4.6e-08	-0.02	0.86	0.12	FALSE
19	GTEx	Cells Transformed fibroblasts	NCOA6	0.09	0.12	enet	25	0.09	1.5e-07	5.5	5.5	4.8e-08	0.06	0.24	0.76	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	ERGIC3	0.08	0.08	lasso	6	0.08	2.6e-10	-4.8	-5.4	5.5e-08	-0.04	0.91	0.09	FALSE
29	METSIM	Adipose	TRPC4AP	0.04	0.03	lasso	5	0.04	1.1e-06	-5.3	5.4	7.7e-08	0.29	0.50	0.49	FALSE
28	METSIM	Adipose	TP53INP2	0.05	0.03	lasso	3	0.04	1.3e-06	5.2	-5.4	8.4e-08	-0.07	0.14	0.86	FALSE
7	GTEx	Artery Tibial	MYH7B	0.14	0.10	lasso	10	0.12	2.9e-09	-5.2	-5.4	8.5e-08	-0.28	0.47	0.53	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	FER1L4	0.04	0.04	blup	309	0.03	4.9e-05	-4.6	5.3	9.9e-08	0.01	0.86	0.05	FALSE
10	GTEx	Brain Hypothalamus	MAP1LC3A	0.19	0.05	lasso	11	0.05	2.2e-02	-4.7	-5.3	1.1e-07	-0.43	0.14	0.10	FALSE
39	The Cancer Genome Atlas	Brain Lower Grade Glioma	EDEM2	0.07	0.02	blup	102	0.04	2.1e-05	-3.3	5.3	1.1e-07	0.24	0.77	0.03	FALSE
20	GTEx	Colon Transverse	MAP1LC3A	0.15	0.14	lasso	3	0.09	3.2e-05	-4.1	-5.3	1.3e-07	-0.56	0.88	0.10	FALSE
22	GTEx	Esophagus Muscularis	CEP250	0.13	0.04	lasso	6	0.03	1.1e-02	-4.2	5.3	1.4e-07	0.04	0.36	0.06	FALSE
5	GTEx	Artery Aorta	EDEM2	0.13	0.08	enet	10	0.07	6.3e-05	-4.8	5.3	1.5e-07	0.30	0.52	0.42	FALSE
23	GTEx	Nerve Tibial	MYH7B	0.21	0.12	lasso	8	0.12	9.7e-09	-5.3	-5.2	1.8e-07	-0.28	0.56	0.44	FALSE
14	GTEx	Breast Mammary Tissue (Female)	ITCH	0.09	0.02	enet	16	0.06	8.2e-03	6.7	5.2	1.9e-07	0.78	0.08	0.61	FALSE
38	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TRPC4AP	0.05	0.03	enet	10	0.04	7.1e-05	-4.8	5.2	2.2e-07	0.18	0.02	0.88	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CEP250	0.02	0.00	blup	344	0.00	1.0e-01	-3.7	5.1	2.8e-07	0.11	0.25	0.05	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	CPNE1	0.34	0.47	enet	11	0.47	8.8e-111	-4.6	5.1	3.0e-07	-0.01	0.49	0.50	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	ERGIC3	0.01	0.00	blup	39	0.01	2.3e-02	-4.8	5.1	3.0e-07	0.04	0.00	0.54	FALSE