[Hub]/) : Traits : Impedance of arm (left) :

chr20:31,884,069-35,298,668

Best TWAS P=3.87e-14 · Best GWAS P=1.37e-12 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CEP250 0.02 0.00 blup 344 0.00 1.0e-01 -3.7 5.1 2.8e-07 0.11 0.25 0.05 FALSE
2 CommonMind Brain Pre-frontal Cortex EDEM2 0.09 0.09 enet 12 0.09 5.8e-11 -4.4 6.1 1.2e-09 0.27 0.96 0.04 FALSE
3 GTEx Adrenal Gland NCOA6 0.10 0.08 lasso 14 0.05 7.7e-03 5.1 5.7 1.3e-08 0.03 0.18 0.38 FALSE
4 GTEx Artery Aorta MYH7B 0.22 0.08 lasso 6 0.09 1.3e-05 -5.3 -5.7 1.6e-08 -0.23 0.50 0.48 FALSE
5 GTEx Artery Aorta EDEM2 0.13 0.08 enet 10 0.07 6.3e-05 -4.8 5.3 1.5e-07 0.30 0.52 0.42 FALSE
6 GTEx Artery Aorta GGT7 0.06 0.00 enet 7 0.02 1.9e-02 5.6 -7.6 3.9e-14 -0.38 0.10 0.60 TRUE
7 GTEx Artery Tibial MYH7B 0.14 0.10 lasso 10 0.12 2.9e-09 -5.2 -5.4 8.5e-08 -0.28 0.47 0.53 FALSE
8 GTEx Brain Cerebellar Hemisphere MYH7B 0.18 0.10 lasso 5 0.08 3.7e-03 -5.3 -5.2 2.3e-07 -0.32 0.39 0.22 TRUE
9 GTEx Brain Cerebellum MYH7B 0.26 0.30 lasso 4 0.26 2.2e-08 -5.3 -5.5 3.2e-08 -0.33 0.46 0.52 FALSE
10 GTEx Brain Hypothalamus MAP1LC3A 0.19 0.05 lasso 11 0.05 2.2e-02 -4.7 -5.3 1.1e-07 -0.43 0.14 0.10 FALSE
11 GTEx Brain Hypothalamus CEP250 0.18 -0.01 lasso 9 0.00 3.4e-01 -4.4 5.7 1.4e-08 0.06 0.11 0.15 TRUE
12 GTEx Brain Nucleus accumbens basal ganglia EDEM2 0.17 0.00 lasso 4 0.00 2.7e-01 -4.9 5.6 1.8e-08 0.32 0.10 0.15 FALSE
13 GTEx Breast Mammary Tissue ITCH 0.09 0.04 enet 28 0.09 2.5e-05 -4.2 6.4 1.9e-10 0.74 0.21 0.76 FALSE
14 GTEx Breast Mammary Tissue (Female) ITCH 0.09 0.02 enet 16 0.06 8.2e-03 6.7 5.2 1.9e-07 0.78 0.08 0.61 FALSE
15 GTEx Cells EBV-transformed lymphocytes PHF20 0.30 -0.01 enet 13 0.04 2.3e-02 -1.7 5.5 3.6e-08 0.12 0.06 0.05 FALSE
16 GTEx Cells EBV-transformed lymphocytes NCOA6 0.11 0.06 enet 15 0.06 3.9e-03 -5.0 5.8 5.7e-09 0.44 0.20 0.24 FALSE
17 GTEx Cells Transformed fibroblasts EDEM2 0.08 0.02 lasso 5 0.03 1.8e-03 -5.3 5.8 6.7e-09 0.22 0.37 0.25 TRUE
18 GTEx Cells Transformed fibroblasts TRPC4AP 0.06 0.01 lasso 2 0.01 4.2e-02 3.4 5.4 8.2e-08 0.15 0.12 0.35 TRUE
19 GTEx Cells Transformed fibroblasts NCOA6 0.09 0.12 enet 25 0.09 1.5e-07 5.5 5.5 4.8e-08 0.06 0.24 0.76 FALSE
20 GTEx Colon Transverse MAP1LC3A 0.15 0.14 lasso 3 0.09 3.2e-05 -4.1 -5.3 1.3e-07 -0.56 0.88 0.10 FALSE
21 GTEx Esophagus Gastroesophageal Junction ITCH 0.11 0.03 lasso 4 0.04 9.9e-03 5.5 5.7 1.3e-08 0.13 0.33 0.06 FALSE
22 GTEx Esophagus Muscularis CEP250 0.13 0.04 lasso 6 0.03 1.1e-02 -4.2 5.3 1.4e-07 0.04 0.36 0.06 FALSE
23 GTEx Nerve Tibial MYH7B 0.21 0.12 lasso 8 0.12 9.7e-09 -5.3 -5.2 1.8e-07 -0.28 0.56 0.44 FALSE
24 GTEx Stomach MAP1LC3A 0.10 0.04 enet 10 0.05 1.3e-03 3.9 -5.6 2.0e-08 -0.51 0.26 0.27 FALSE
25 GTEx Testis LINC00657 0.08 0.05 enet 15 0.05 3.0e-03 -5.0 5.4 5.1e-08 0.04 0.64 0.03 TRUE
26 GTEx Thyroid TP53INP2 0.09 0.05 lasso 7 0.04 3.7e-04 5.5 -5.9 3.0e-09 -0.10 0.09 0.90 TRUE
27 GTEx Thyroid MYH7B 0.06 0.03 enet 15 0.06 3.6e-05 -5.0 -6.1 1.1e-09 -0.37 0.70 0.19 FALSE
28 METSIM Adipose TP53INP2 0.05 0.03 lasso 3 0.04 1.3e-06 5.2 -5.4 8.4e-08 -0.07 0.14 0.86 FALSE
29 METSIM Adipose TRPC4AP 0.04 0.03 lasso 5 0.04 1.1e-06 -5.3 5.4 7.7e-08 0.29 0.50 0.49 FALSE
30 ROSMAP Brain Pre-frontal Cortex SPAG4 0.05 0.04 enet 8 0.04 5.7e-06 -4.4 5.5 4.6e-08 -0.02 0.86 0.12 FALSE
31 ROSMAP Brain Pre-frontal Cortex FER1L4 0.04 0.04 blup 309 0.03 4.9e-05 -4.6 5.3 9.9e-08 0.01 0.86 0.05 FALSE
32 ROSMAP Brain Pre-frontal Cortex RALY 0.09 0.16 lasso 7 0.15 2.7e-18 6.7 6.6 5.4e-11 0.83 0.14 0.86 TRUE
33 ROSMAP Brain Pre-frontal Cortex ERGIC3 0.08 0.08 lasso 6 0.08 2.6e-10 -4.8 -5.4 5.5e-08 -0.04 0.91 0.09 FALSE
34 YFS Blood TP53INP2 0.02 0.02 lasso 15 0.01 1.3e-05 5.5 -5.7 1.5e-08 -0.09 0.13 0.86 FALSE
35 The Cancer Genome Atlas Breast Invasive Carcinoma CPNE1 0.34 0.47 enet 11 0.47 8.8e-111 -4.6 5.1 3.0e-07 -0.01 0.49 0.50 FALSE
36 The Cancer Genome Atlas Breast Invasive Carcinoma ERGIC3 0.01 0.00 blup 39 0.01 2.3e-02 -4.8 5.1 3.0e-07 0.04 0.00 0.54 FALSE
37 The Cancer Genome Atlas Colon Adenocarcinoma NCOA6 0.06 0.03 lasso 1 0.02 2.0e-02 5.5 5.5 3.5e-08 0.08 0.02 0.79 FALSE
38 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TRPC4AP 0.05 0.03 enet 10 0.04 7.1e-05 -4.8 5.2 2.2e-07 0.18 0.02 0.88 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma EDEM2 0.07 0.02 blup 102 0.04 2.1e-05 -3.3 5.3 1.1e-07 0.24 0.77 0.03 FALSE
40 The Cancer Genome Atlas Brain Lower Grade Glioma NCOA6 0.04 0.02 blup 65 0.04 6.1e-05 5.5 6.6 5.1e-11 0.22 0.02 0.95 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma RALY 0.05 0.04 blup 53 0.05 1.6e-05 6.5 -6.5 1.1e-10 -0.94 0.03 0.96 FALSE