[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr3:9,283,299-11,999,795

Best TWAS P=5.11e-13 · Best GWAS P=2.71e-12 conditioned to 7.24e-05

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	GTEx	Testis	CRELD1	0.22	0.22	lasso	8	0.26	1.1e-11	5.5	-7.2	5.1e-13	0.00	0.14	0.86	TRUE
12	GTEx	Cells Transformed fibroblasts	HRH1	0.20	0.00	lasso	3	0.01	1.1e-01	7.0	-5.8	6.3e-09	-0.77	0.01	0.92	TRUE
6	GTEx	Artery Aorta	RP11-1020A11.1	0.15	0.01	lasso	3	0.00	4.0e-01	-6.0	-6.8	9.9e-12	-0.03	0.03	0.56	FALSE
10	GTEx	Cells Transformed fibroblasts	CRELD1	0.39	0.19	enet	39	0.28	4.5e-21	-6.0	-6.5	1.0e-10	0.04	0.03	0.97	FALSE
13	GTEx	Cells Transformed fibroblasts	RP11-1020A11.1	0.20	0.10	enet	67	0.09	1.9e-07	-6.0	-6.2	6.2e-10	0.01	0.03	0.96	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC401052	0.06	0.07	enet	6	0.06	3.5e-07	6.2	-6.1	1.3e-09	-0.05	0.01	0.99	FALSE
15	GTEx	Esophagus Muscularis	CRELD1	0.21	0.10	lasso	1	0.08	1.7e-05	-6.0	-6.0	1.5e-09	-0.02	0.03	0.93	FALSE
1	GTEx	Adipose Subcutaneous	CRELD1	0.46	0.16	enet	51	0.27	2.2e-22	-6.0	-6.0	1.6e-09	0.07	0.03	0.97	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	CIDECP	0.04	0.02	blup	33	0.03	3.8e-04	5.5	6.0	1.7e-09	0.00	0.04	0.90	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	AC022007.5	0.05	0.02	blup	515	0.03	2.8e-04	6.1	6.0	2.3e-09	0.02	0.04	0.96	FALSE
25	YFS	Blood	FANCD2	0.04	0.04	lasso	1	0.04	7.7e-13	6.0	-6.0	2.4e-09	-0.06	0.04	0.96	FALSE
8	GTEx	Breast Mammary Tissue	CRELD1	0.25	0.19	lasso	6	0.18	2.2e-09	-6.0	-5.8	5.8e-09	-0.02	0.03	0.97	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	AC034193.5	0.15	0.09	enet	11	0.08	3.3e-05	5.5	5.8	6.3e-09	0.02	0.41	0.48	FALSE
3	GTEx	Adipose Visceral Omentum	CRELD1	0.19	0.12	lasso	4	0.10	4.1e-06	-6.0	-5.8	8.9e-09	-0.02	0.04	0.88	FALSE
23	METSIM	Adipose	BRK1	0.04	0.02	bslmm	559	0.01	8.9e-03	5.0	-5.7	9.1e-09	-0.04	0.15	0.68	FALSE
22	GTEx	Thyroid	BRK1	0.08	0.05	lasso	3	0.04	6.8e-04	5.5	-5.7	1.2e-08	0.01	0.30	0.68	FALSE
5	GTEx	Artery Aorta	AC034193.5	0.12	0.01	lasso	3	0.00	1.6e-01	5.6	5.6	2.2e-08	-0.01	0.17	0.38	FALSE
11	GTEx	Cells Transformed fibroblasts	AC034193.5	0.12	0.05	lasso	3	0.05	1.2e-04	5.5	5.6	2.5e-08	-0.03	0.43	0.55	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	CYCSP10	0.19	0.01	lasso	5	-0.01	6.6e-01	5.5	-5.6	2.6e-08	0.01	0.07	0.15	FALSE
2	GTEx	Adipose Subcutaneous	AC034193.5	0.08	0.07	lasso	4	0.07	2.2e-06	5.3	5.5	3.2e-08	0.00	0.54	0.43	FALSE
14	GTEx	Esophagus Mucosa	VHL	0.14	0.00	lasso	1	0.00	2.9e-01	5.5	-5.5	3.2e-08	0.02	0.08	0.34	FALSE
7	GTEx	Artery Tibial	AC034193.5	0.10	0.08	lasso	1	0.06	1.2e-05	5.5	5.5	3.3e-08	-0.02	0.40	0.59	FALSE
19	GTEx	Skin Sun Exposed Lower leg	AC034193.5	0.09	0.11	lasso	2	0.09	8.7e-08	5.5	5.5	3.5e-08	-0.02	0.44	0.56	FALSE
4	GTEx	Artery Aorta	CRELD1	0.30	0.07	lasso	7	0.12	2.4e-07	-6.0	-5.5	4.4e-08	0.03	0.04	0.96	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C3orf10	0.03	0.05	lasso	5	0.04	3.4e-05	5.4	-5.5	4.8e-08	-0.01	0.06	0.93	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	C3orf10	0.01	0.01	blup	49	0.01	9.4e-03	4.9	-5.4	5.7e-08	0.02	0.07	0.38	FALSE
21	GTEx	Thyroid	CIDECP	0.11	0.12	lasso	2	0.11	1.1e-08	5.3	5.4	7.2e-08	0.00	0.53	0.46	FALSE
26	YFS	Blood	PRRT3	0.08	0.02	bslmm	469	0.04	7.4e-13	-6.0	-5.4	8.1e-08	-0.03	0.03	0.97	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	C3orf10	0.05	0.02	blup	49	0.04	9.3e-05	5.1	-5.4	8.1e-08	-0.03	0.09	0.90	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf10	0.02	0.03	blup	49	0.02	1.8e-03	5.4	-5.2	1.6e-07	0.02	0.06	0.75	FALSE
30	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C3orf10	0.05	0.04	lasso	3	0.04	1.4e-03	5.1	-5.2	1.6e-07	0.02	0.12	0.59	FALSE
16	GTEx	Pancreas	BRK1	0.22	0.20	lasso	9	0.15	6.3e-07	5.0	-5.2	1.8e-07	0.01	0.83	0.16	FALSE
18	GTEx	Skin Sun Exposed Lower leg	CRELD1	0.29	0.15	enet	36	0.23	8.2e-19	-6.0	-5.2	2.2e-07	0.04	0.03	0.97	FALSE