TWAS hub - CYCSP10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.319	0.105	0.0051	-0.010	NA	0.005	NA	-0.008	0.89	NA	0.22	NA	0.63
2	GTEx	Cells EBV-transformed lymphocytes	0.186	0.082	0.0097	0.009	NA	-0.009	NA	-0.007	0.16	NA	0.83	NA	0.66

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Ulcerative Colitis	7.4	10.7	12.3	-3.0	3.5
Long-standing illness, disability or infirmity	5.8	8.9	10.2	2.8	-3.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.7	6.8	9.4	-2.0	3.1
Ulcerative Colitis (UC)	5.2	9.7	10.5	-3.2	3.0
Medication: Aspirin	4.4	5.9	9.3	1.6	-3.0
Weight	4.3	21.0	27.9	3.8	-5.3
Arm predicted mass (left)	4.3	21.9	28.4	3.9	-5.3
Leg fat-free mass (right)	4.2	22.5	31.0	3.8	-5.6
Leg predicted mass (right)	4.2	22.2	31.1	3.7	-5.6
Hip circumference	4.1	17.7	23.4	3.5	-4.8
Leg fat-free mass (left)	4.0	21.4	29.5	3.6	-5.4
Leg predicted mass (left)	3.9	20.9	29.1	3.6	-5.4
Arm fat-free mass (right)	3.9	20.1	25.2	3.9	-5.0
Basal metabolic rate	3.9	21.8	28.8	3.8	-5.4
Arm fat-free mass (left)	3.8	19.1	26.6	3.4	-5.2
Arm predicted mass (right)	3.7	18.9	24.7	3.6	-5.0
Whole body fat-free mass	3.7	21.0	27.7	3.8	-5.3
Whole body water mass	3.7	21.0	28.1	3.7	-5.3
Medication: Aspirin	3.6	4.7	7.1	1.5	-2.7
Illnesses of siblings	3.5	4.9	7.6	-1.5	2.8
Serious illness, injury or assault to yourself	3.4	4.2	4.2	2.0	-2.0
Leg fat mass (left)	3.4	13.5	15.4	3.4	-3.9
Medication: Co-codamol	3.2	3.8	7.1	0.7	-2.7
Leg fat mass (right)	3.1	12.1	13.8	3.2	-3.7
Trunk fat mass	3.0	13.1	16.3	3.1	-4.0
Trunk fat-free mass	2.9	16.7	22.0	3.4	-4.7
Worry too long after embarrassment	2.9	4.9	6.5	1.8	2.5
Arm fat mass (left)	2.9	12.0	15.6	2.9	-4.0
Body mass index (BMI)	2.8	11.7	13.8	3.1	-3.7
Whole body fat mass	2.8	11.8	14.9	3.0	-3.9
Waist circumference	2.7	9.8	13.1	2.6	-3.6
Trunk predicted mass	2.7	15.7	20.7	3.3	-4.6
Arm fat mass (right)	2.6	10.7	13.3	2.8	-3.6
Alcohol intake versus 10 years previously	2.5	3.8	5.9	1.3	-2.4
Knee pain experienced in last month	2.5	3.8	7.2	0.7	-2.7
Bipolar Disorder (2011)	2.4	2.3	2.8	-1.3	1.7
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	6.8	2.6	-0.7
Comparative height size at age 10	2.4	13.3	20.4	2.5	-4.5
Angina	2.3	3.0	5.9	-0.0	-2.4
Exposure to tobacco smoke outside home	2.2	2.9	5.6	-2.4	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.5	3.5	-1.9	1.2
Qualifications: College or University degree	2.2	7.0	7.5	-2.7	2.5
Angina (self-reported)	2.2	2.9	5.9	-0.1	-2.4
Commuting to job workplace: Walk	2.1	2.3	4.6	-0.1	-2.1
Pain experienced in last month	2.1	3.5	6.8	-0.5	2.6
Irritable Bowel Disease (IBD)	2.0	4.8	5.6	-2.4	2.0
Impedance of leg (right)	2.0	9.5	14.5	-2.1	3.8
Impedance of whole body	2.0	10.0	12.3	-2.8	3.5
BMI	1.9	11.2	17.9	2.1	-4.2
Impedance of arm (right)	1.9	8.6	9.4	-2.8	3.1
Time employed in main current job	1.9	2.2	4.3	0.4	2.1
Heart disease (mother)	1.9	2.3	3.8	0.9	-1.9
Average weekly red wine intake	1.9	2.7	5.4	0.2	-2.3
Medication for hormone replacement therapy	1.8	2.0	3.6	1.9	0.6
Trunk fat percentage	1.8	7.4	8.7	2.4	-3.0
Mouth/teeth dental problems: Bleeding gums	1.8	2.4	2.7	1.6	-1.4
High blood pressure (siblings)	1.8	2.6	2.9	1.7	-1.5
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.2	4.4	-2.1	-0.1
Miserableness	1.8	3.1	3.4	1.8	-1.7
Alcohol drinker status: Never	1.8	2.1	4.2	0.2	-2.0
Neuroticism (2016)	1.7	2.4	4.7	2.2	0.4
Medication: Atenolol	1.7	2.2	4.4	-2.1	0.0
Impedance of leg (left)	1.7	8.3	13.2	-1.8	3.6
Impedance of arm (left)	1.7	8.0	8.0	-2.8	2.8
Body fat percentage	1.7	6.9	7.0	2.6	-2.7
Migraine (self-reported)	1.7	2.2	2.9	1.2	-1.7
Tinnitus: Yes, now most or all of the time	1.7	2.0	2.7	-1.1	1.6
Irritability	1.7	2.9	4.3	2.1	-1.2
Age started oral contraceptive pill	1.7	2.1	3.1	1.1	1.8
Smoking Status	1.6	3.9	7.7	0.2	-2.8
Bilateral oophorectomy (both ovaries removed)	1.6	1.8	3.7	0.2	-1.9
Qualifications: O levels/GCSEs or equivalent	1.6	2.5	4.9	-2.2	0.0
Emphysema/chronic bronchitis	1.6	1.8	3.0	1.7	-0.8
Osteoarthritis (self-reported)	1.6	2.1	3.3	0.9	-1.8
Leg fat percentage (left)	1.6	6.0	7.5	2.7	-2.1
Heart disease (siblings)	1.6	2.0	2.6	1.2	-1.6
Supplements: Vitamin C	1.5	1.7	3.0	1.7	-0.7
Arm fat percentage (left)	1.5	6.0	6.4	2.4	-2.5
Number of operations (self-reported)	1.5	2.2	3.9	-0.6	-2.0
Heart attack/myocardial infarction (self-reported)	1.5	1.9	2.3	1.2	-1.5
Supplements: Zinc	1.4	1.6	3.1	1.8	0.2
Number of incorrect matches in round	1.4	2.3	3.9	2.0	0.9
Arm fat percentage (right)	1.4	5.7	5.7	2.4	-2.4
Birth weight	1.4	3.0	6.1	-0.2	-2.5
Leg fat percentage (right)	1.4	5.1	6.9	2.6	-1.8
Back pain experienced in last month	1.4	2.0	2.7	1.1	-1.6
Hypothyroidism (self reported)	1.3	2.9	3.8	-1.9	1.4
Heart attack	1.3	1.7	2.2	1.1	-1.5
Breast cancer (self-reported)	1.3	1.5	3.0	0.1	1.7
Medication: Blood pressure	1.3	2.4	3.8	-1.0	-1.9
Schizophrenia (2014)	1.2	2.7	5.3	-0.4	2.3
Type 2 Diabetes (T2D) (2012)	1.2	1.4	2.1	0.8	1.5
Number of treatments/medications taken	1.2	2.1	3.9	0.6	-2.0
Sitting height	1.2	8.8	14.4	1.8	-3.8
Headache pain in last month	1.2	2.1	3.4	0.9	-1.8
Number of full brothers	1.2	1.5	1.6	1.2	-1.2
Had major operations	1.2	1.4	2.7	0.3	-1.6
Age at last live birth	1.2	1.7	3.3	-0.4	1.8
Diabetes diagnosed by doctor	1.2	1.9	3.8	0.0	-2.0
Mother’s age at death	1.2	1.5	2.7	-1.6	0.5
Medication: Atorvastatin	1.2	1.5	2.0	-1.0	1.4
Depressed Affect (Nagel 2018)	1.1	2.3	4.5	2.1	-0.3
Lupus	1.1	1.7	2.9	-1.7	-0.8
Type 2 Diabetes (T2D) (2018)	1.1	2.1	4.3	0.0	-2.1
Lung FEV1/FVC ratio	1.1	5.5	9.3	-1.3	3.0
Medication: Metformin	1.1	1.5	3.1	0.0	-1.8
Qualifications: None of the above	1.1	2.3	4.5	2.1	-0.1
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	2.2	-0.8	1.5
Noisy workplace	1.1	1.4	2.7	-1.6	0.3
Pulse wave Arterial Stiffness index	1.1	1.3	2.6	0.3	1.6
Ever highly irritable/argumentative for 2 days	1.1	1.4	2.6	1.6	0.4
Age at first live birth	1.1	2.0	3.3	-0.9	1.8
Pulse wave peak to peak time	1.1	1.3	2.6	-0.3	-1.6
Alcohol intake frequency.	1.1	2.5	4.6	0.5	-2.2
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.5	-1.6	-0.4
Ever had prostate specific antigen (PSA) test	1.1	1.3	2.5	1.6	-0.3
Major Depression (MDD)	1.0	1.2	2.2	-1.5	-0.3
LDL Cholesterol	1.0	1.5	2.6	1.6	0.6
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.5	1.6	-0.0
Standing height	1.0	10.1	17.1	1.8	-4.1
Eye problems/disorders: None of the above	1.0	1.1	2.1	-0.3	1.5
Neck or shoulder pain in last month	1.0	1.4	2.5	0.5	-1.6
Overall health rating	1.0	2.2	4.0	2.0	-0.6
Smoking status: Previous	1.0	1.5	3.0	0.2	-1.7
Vascular/heart problems diagnosed by doctor	1.0	2.6	3.9	1.1	2.0
Neuroticism	0.9	2.1	3.3	1.8	0.9
Relative age voice broke	0.9	1.4	2.6	-1.6	-0.5
Taking other prescription medications	0.9	1.3	1.8	0.9	-1.3
Hayfever, allergic rhinitis or eczema	0.9	2.0	3.3	-1.8	0.9
Mouth/teeth dental problems	0.9	1.3	1.9	-0.8	1.4
Pain all over the body in last month	0.9	1.0	1.1	0.9	-1.1
Qualifications: A levels/AS levels or equivalent	0.9	2.0	3.7	-0.5	1.9
Prospective memory result	0.9	1.2	2.2	-1.5	0.3
Tense / ‘highly strung’	0.9	1.4	1.5	1.2	1.2
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.0	1.4	0.0
Medication for pain relief, constipation, heartburn	0.9	1.5	2.3	-0.8	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	1.5	-0.7	-1.2
Financial situation satisfaction	0.9	1.2	1.9	-0.6	-1.4
Medication: Lisinopril	0.9	1.1	1.6	-0.8	-1.3
Supplements: Calcium	0.9	1.0	1.8	0.4	1.3
Height	0.8	16.3	31.7	0.9	-5.6
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.7	0.1	-1.3
Financial difficulties in last 2 years	0.8	1.1	2.0	0.3	1.4
Neuroticism score	0.8	1.7	2.1	1.5	1.1
Father’s age at death	0.8	1.0	1.6	1.3	-0.6
Medication: Gliclazide	0.8	0.9	1.0	-1.0	-0.8
Neuroticism (Nagel 2018)	0.7	1.7	3.4	1.8	0.3
Schizophrenia vs Biploar Disorder	0.7	1.0	1.7	-1.3	0.5
High blood pressure	0.7	1.8	1.9	-1.4	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	1.4	1.0	-1.2
Number of live births	0.7	1.0	1.4	-0.8	1.2
Pulse wave reflection index	0.7	0.8	1.7	0.0	1.3
Number of full sisters	0.7	0.8	1.6	-1.3	0.1
Suffer from ‘nerves’	0.7	1.2	1.4	1.2	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.3	1.5	-0.7
Ever had bowel cancer screening	0.7	0.8	1.6	1.3	-0.0
Friendships satisfaction	0.7	0.8	1.6	0.1	1.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	1.1	-1.0	-1.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.5	-0.6	-1.2
Unable to work because of sickness or disability	0.7	0.9	1.0	1.0	0.8
Alzheimer’s Disease (in mother)	0.6	0.7	0.8	-0.7	0.9
Ovarian Cancer	0.6	0.8	0.8	-0.9	0.9
Prostate Cancer	0.6	0.8	1.6	0.1	1.3
Heel T-Score	0.6	4.6	6.8	1.5	2.6
Hearing difficulty/problems: Yes	0.6	1.0	1.9	-0.0	-1.4
Diabetes (father)	0.6	0.7	1.4	0.3	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.2	-0.7	-1.1
Supplements: Glucosamine	0.6	0.8	1.5	-0.4	1.2
Hearing difficulty/problems with background noise	0.6	1.0	1.5	-0.7	1.2
Had other major operations	0.6	0.8	1.4	-0.4	1.2
Loud music exposure frequency	0.6	0.7	1.1	-0.5	1.1
Hypertension (Self-reported)	0.6	1.7	1.8	-1.4	-1.3
Illnesses of father: Heart disease	0.6	0.9	1.8	-1.3	0.1
Loneliness, isolation	0.6	0.8	1.3	1.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.3	1.1	0.0
Medication for cholesterol	0.6	0.9	1.6	0.5	1.3
Guilty feelings	0.6	1.0	1.3	0.7	1.2
Illnesses of father: High blood pressure	0.6	0.7	1.2	-0.5	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.2	-0.5	-1.1
Rheumatoid Arthritis	0.5	0.7	1.3	0.4	-1.1
Blood Eosinophil Count	0.5	3.8	4.0	-2.0	1.9
Cardiovascular Disease	0.5	1.6	2.9	-0.5	-1.7
Relative age of first facial hair	0.5	1.1	2.0	-1.4	-0.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	0.7	0.8	-0.8
Ever had hysterectomy (womb removed)	0.5	0.6	0.7	0.7	-0.8
Vitamin and mineral supplements	0.5	0.7	1.4	0.2	-1.2
Pack years adult smoking proportion	0.5	0.8	1.4	-1.2	-0.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.1	-0.3	-1.0
Allergy	0.5	1.2	2.4	1.6	-0.1
Medication: Ramipril	0.5	0.6	1.1	0.2	-1.1
Eye problems/disorders: Cataract	0.5	0.6	1.1	0.2	-1.1
Osteoporosis (self-reported)	0.5	0.6	0.6	-0.8	0.8
Illnesses of father: None of the above (group 1)	0.5	0.6	1.3	1.1	-0.1
Number of self-reported non-cancer illnesses	0.5	0.9	1.7	-0.3	-1.3
Wears glasses or contact lenses	0.5	0.6	1.0	-0.4	1.0
Supplements: Fish oil (including cod liver oil)	0.5	0.7	1.3	1.1	-0.1
Risk taking	0.5	0.7	1.0	0.6	-1.0
Alcohol drinker status: Previous	0.5	0.5	0.8	-0.9	0.5
Worry (Nagel 2018)	0.4	0.8	0.9	1.0	0.8
Alzheimer’s Disease (including proxy)	0.4	0.5	0.8	0.4	0.9
Breast Cancer	0.4	0.9	1.5	-0.6	-1.2
Mean Putamen Volume	0.4	0.4	0.6	0.5	-0.8
Severe depression (siblings)	0.4	0.4	0.7	0.9	-0.3
Past tobacco smoking	0.4	0.7	1.5	0.1	1.2
Alcohol usually taken with meals	0.4	0.7	1.2	1.1	-0.4
Breastfed as a baby	0.4	0.5	0.6	-0.7	0.7
Wheeze or whistling in the chest in last year	0.4	0.7	1.3	0.4	-1.1
Medication: Omeprazole	0.4	0.5	0.7	-0.5	-0.8
Illnesses of siblings: Diabetes	0.4	0.5	0.7	-0.6	-0.8
Mood swings	0.4	0.8	1.4	1.2	-0.3
Average weekly champagne plus white wine intake	0.4	0.5	1.0	-1.0	-0.1
Ever smoked	0.4	0.8	1.5	-0.2	-1.2
Average weekly beer plus cider intake	0.4	0.5	0.8	-0.4	0.9
Commuting to job workplace: Cycle	0.4	0.5	0.7	0.8	0.7
Basal cell carcinoma (self-reported)	0.4	0.5	1.1	0.1	1.0
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.1	-0.5	1.0
Body Mass Index (BMI) (2010)	0.3	0.4	0.4	0.7	0.5
Crohns Disease (2012)	0.3	0.5	0.9	-0.4	1.0
Waist Hip Ratio (WHR)	0.3	1.2	1.3	-1.0	1.1
Chronotype (morning person)	0.3	0.6	1.2	-0.0	-1.1
Hand grip strength (left)	0.3	0.7	0.7	0.9	-0.8
Hand grip strength (right)	0.3	0.8	1.4	0.6	-1.2
Average weekly fortified wine intake	0.3	0.4	0.6	-0.3	0.8
Age when periods started (menarche)	0.3	0.6	1.1	-0.4	1.0
Stomach or abdominal pain in last month	0.3	0.3	0.3	-0.6	-0.6
Nervous feelings	0.3	0.5	0.8	0.9	-0.4
Hair/balding pattern: Pattern 2	0.3	0.4	0.6	-0.8	0.4
Diabetes (self-reported)	0.3	0.4	0.9	0.1	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.5	0.5	-0.7
Mouth/teeth dental problems: Dentures	0.3	0.4	0.7	0.4	-0.9
Depression (self-reported)	0.3	0.4	0.7	-0.8	0.2
Medication: Lansoprazole	0.3	0.4	0.7	-0.8	-0.1
Length of working week for main job	0.3	0.4	0.6	0.4	-0.7
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.0	0.2	1.0
Glaucoma (self-reported)	0.3	0.3	0.4	-0.6	0.6
Gout (self-reported)	0.3	0.4	0.7	-0.8	-0.2
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.3	0.6	-0.6
Medication: Allopurinol	0.3	0.4	0.6	-0.5	-0.8
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.6	0.3	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.7	-0.8	0.0
Asthma (self-reported)	0.3	0.6	0.6	-0.8	0.7
High cholesterol (Self-reported)	0.3	0.5	0.9	-1.0	0.3
Fractured/broken bones in last 5 years	0.3	0.4	0.8	-0.0	-0.9
Pack years of smoking	0.3	0.4	0.6	-0.8	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	0.8	0.2	0.9
Schizophrenia (2018)	0.2	0.4	0.8	-0.1	0.9
HbA1C	0.2	0.2	0.3	0.2	-0.5
Triglycerides	0.2	0.3	0.5	-0.7	-0.4
Respiratory disease	0.2	0.5	0.6	-0.8	-0.6
Hair Pigment	0.2	4.5	8.6	0.5	-2.9
Sensitivity / hurt feelings	0.2	0.4	0.6	-0.5	0.8
Diabetes (mother)	0.2	0.3	0.5	-0.3	-0.7
Current tobacco smoking	0.2	0.4	0.7	-0.3	-0.8
Fed-up feelings	0.2	0.3	0.4	0.6	0.5
High blood pressure (mother)	0.2	0.3	0.4	0.7	-0.3
Had menopause	0.2	0.2	0.4	0.6	0.2
Medication: Simvastatin	0.2	0.4	0.6	0.4	-0.7
Worrier / anxious feelings	0.2	0.4	0.7	0.8	0.2
Falls in the last year	0.2	0.2	0.4	-0.0	0.7
Happiness	0.2	0.3	0.4	-0.3	0.6
Asthma	0.2	0.4	0.4	-0.6	0.7
Lung cancer (father)	0.2	0.3	0.4	-0.6	0.4
Illnesses of mother	0.2	0.2	0.4	-0.2	0.6
Exposure to tobacco smoke at home	0.2	0.2	0.4	-0.6	0.3
Blood clot in the leg (DVT)	0.2	0.3	0.4	0.5	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.5	-0.6	0.7
Forced vital capacity (FVC), Best measure	0.2	0.6	1.2	-0.1	-1.1
Comparative body size at age 10	0.2	0.5	0.7	-0.8	-0.6
Health satisfaction	0.2	0.3	0.6	-0.1	-0.8
Medication: Seretide 50 evohaler	0.2	0.2	0.3	-0.2	0.6
Chest pain or discomfort	0.2	0.3	0.6	-0.8	-0.2
Family relationship satisfaction	0.2	0.3	0.4	-0.7	0.4
Leg pain on walking	0.2	0.3	0.3	-0.6	-0.5
Mineral and other dietary supplements	0.2	0.3	0.4	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.6	-0.4	0.8
Medication: Paracetamol	0.2	0.3	0.4	-0.6	-0.4
Ever depressed for a whole week	0.2	0.3	0.6	-0.7	0.2
Myopia	0.2	0.3	0.4	0.6	-0.4
Cholesterol lowering medication	0.2	0.3	0.4	-0.5	0.7
Bipolar Disorder (2018)	0.1	0.1	0.2	0.4	0.3
Depression (Nagel 2018)	0.1	0.2	0.4	0.1	-0.6
Alzheimer’s Disease (in father)	0.1	0.1	0.2	0.4	-0.0
Reaction Time	0.1	0.2	0.3	0.5	0.5
Age at First Birth	0.1	0.2	0.3	-0.5	-0.2
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.1	0.5
HDL Cholesterol	0.1	0.2	0.3	-0.1	0.6
Primary Biliary Cirrhosis	0.1	0.2	0.3	-0.6	-0.3
Blood White Count	0.1	0.8	1.5	0.0	-1.2
Allergy or Eczema	0.1	0.4	0.6	-0.4	0.8
Tanning	0.1	1.3	2.3	0.6	-1.5
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.2	-0.0	0.4
Townsend deprivation index at recruitment	0.1	0.1	0.2	-0.5	0.1
Qualifications: CSEs or equivalent	0.1	0.2	0.3	0.3	0.5
Multivitamins +/- minerals	0.1	0.1	0.1	-0.3	0.2
Forced vital capacity (FVC)	0.1	0.5	1.0	-0.0	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.2	0.3	0.4
Fluid intelligence score	0.1	0.2	0.4	0.6	0.0
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	0.6	0.1
Pulse rate	0.1	0.2	0.4	-0.1	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.3	0.6	0.1
Medication: Cholesterol lowering	0.1	0.2	0.4	-0.2	-0.7
Hair/balding pattern: Pattern 4	0.1	0.3	0.5	0.3	-0.7
Peak expiratory flow (PEF)	0.1	0.2	0.3	-0.0	0.6
Medication: Paracetamol	0.1	0.2	0.3	-0.5	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.3	0.6	0.2
Shortness of breath walking on level ground	0.1	0.1	0.3	-0.5	-0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	-0.2	0.4
Medication: Blood pressure	0.1	0.3	0.4	0.4	-0.6
Medication: Ibuprofen	0.1	0.1	0.1	0.2	-0.3
Mean time to correctly identify matches	0.1	0.1	0.2	0.1	0.5
Qualifications: nursing, teaching	0.1	0.1	0.2	0.4	0.3
Smoking status: Current	0.1	0.2	0.3	-0.3	-0.5
Ever taken oral contraceptive pill	0.1	0.1	0.1	-0.1	-0.4
Hearing aid user	0.1	0.1	0.1	-0.3	-0.2
Commuting to job workplace: Public transport	0.1	0.2	0.3	0.2	0.5
Medication: Bendroflumethiazide	0.1	0.1	0.3	-0.1	0.5
Diastolic blood pressure, automated reading	0.1	0.2	0.2	-0.3	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.2	0.4	-0.5
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.3	0.5	0.1
Crohns Disease (2017)	0.0	0.1	0.1	0.0	0.3
Fasting Glucose	0.0	0.0	0.1	0.0	0.3
Blood Platelet Count	0.0	0.0	0.0	-0.2	-0.2
Blood Red Count	0.0	0.4	0.5	0.6	-0.7
Systolic Blood Pressure	0.0	0.2	0.5	-0.7	-0.1
Lung FVC	0.0	0.2	0.4	0.6	-0.1
Average weekly spirits intake	0.0	0.1	0.1	-0.3	-0.2
Systolic blood pressure, automated reading	0.0	0.1	0.3	0.5	-0.1
Maternal smoking around birth	0.0	0.0	0.0	0.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	-0.3	-0.3
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	-0.0	-0.2
Medication: Levothyroxine sodium	0.0	0.1	0.1	-0.3	0.2
Chronic bronchitis/emphysema (father)	0.0	0.1	0.1	-0.1	-0.3
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.0	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1)	0.0	0.0	0.1	-0.3	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.0	0.0	-0.2	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.1	0.1	-0.1	0.3
Birth weight of first child	0.0	0.0	0.0	0.0	0.2
Medication: Amlodipine	0.0	0.0	0.1	-0.2	-0.1
Number of children fathered	0.0	0.0	0.1	-0.3	-0.0
Pulse rate, automated reading	0.0	0.1	0.1	0.3	-0.2
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.0	-0.1	0.1
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	0.2	0.1

Hub : Genes

CYCSP10

Models

Trait associations