[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr5:136,723,696-141,087,689

Best TWAS P=6.14e-13 · Best GWAS P=1.02e-15 conditioned to 0.00219

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
27	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBE2D2	0.05	0.02	enet	6	0.03	4.4e-04	5.0	7.2	6.1e-13	0.91	0.01	0.97	TRUE
19	ROSMAP	Brain Pre-frontal Cortex	WNT8A	0.05	0.01	blup	300	0.03	1.0e-04	-1.5	-6.4	1.5e-10	0.00	0.08	0.87	TRUE
14	GTEx	Nerve Tibial	HARS	0.07	0.01	enet	16	0.04	1.1e-03	-4.8	6.0	2.1e-09	-0.04	0.08	0.86	TRUE
20	ROSMAP	Brain Pre-frontal Cortex	KDM3B	0.07	0.01	blup	307	0.03	1.0e-04	4.6	-5.5	3.8e-08	-0.09	0.10	0.84	TRUE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	EGR1	0.02	0.01	blup	41	0.02	1.9e-03	-4.9	-5.4	5.4e-08	-0.03	0.11	0.08	TRUE
11	GTEx	Esophagus Gastroesophageal Junction	DNAJC18	0.17	0.01	lasso	10	0.04	2.0e-02	4.3	6.8	1.3e-11	0.77	0.06	0.71	FALSE
21	YFS	Blood	CXXC5	0.01	0.00	bslmm	244	0.01	2.6e-03	8.0	-6.4	1.5e-10	-0.47	0.02	0.80	FALSE
28	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	BRD8	0.12	0.07	lasso	4	0.05	1.2e-03	6.6	-6.2	4.0e-10	0.00	0.00	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC18	0.09	0.10	bslmm	260	0.10	2.5e-12	3.9	6.0	2.6e-09	0.64	1.00	0.00	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	DNAJC18	0.26	0.09	lasso	2	0.12	9.7e-05	4.2	5.9	3.9e-09	0.77	0.04	0.84	FALSE
10	GTEx	Colon Transverse	DNAJC18	0.37	-0.01	lasso	5	0.01	1.1e-01	4.2	5.8	6.0e-09	0.59	0.06	0.07	FALSE
18	GTEx	Vagina	PURA	0.52	0.05	enet	51	0.09	3.6e-03	4.5	-5.8	6.2e-09	-0.12	0.06	0.10	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FAM53C	0.05	0.02	bslmm	291	0.03	4.1e-04	7.3	5.8	8.2e-09	0.03	0.03	0.92	FALSE
16	GTEx	Skin Sun Exposed Lower leg	WDR55	0.04	0.01	enet	10	0.01	2.8e-02	-4.8	-5.7	1.2e-08	0.01	0.08	0.82	FALSE
22	YFS	Blood	TMCO6	0.01	0.00	blup	329	0.01	4.1e-03	-4.8	-5.6	2.5e-08	0.02	0.09	0.88	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PCDHA2	0.04	0.03	blup	478	0.03	5.0e-05	-4.8	-5.5	2.9e-08	-0.05	0.08	0.91	FALSE
12	GTEx	Esophagus Muscularis	DNAJC18	0.22	0.10	lasso	6	0.13	3.2e-08	4.2	5.5	3.2e-08	0.59	0.55	0.12	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	WDR55	0.09	0.08	enet	12	0.12	1.5e-07	-4.9	-5.5	4.1e-08	0.01	0.02	0.97	FALSE
8	GTEx	Cells Transformed fibroblasts	CD14	0.09	0.05	lasso	4	0.06	2.7e-05	-4.0	-5.4	5.7e-08	-0.01	0.21	0.72	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	WDR55	0.07	0.06	blup	44	0.06	1.7e-06	-4.9	-5.4	8.0e-08	-0.01	0.02	0.97	FALSE
17	GTEx	Spleen	DNAJC18	0.30	0.13	lasso	5	0.20	6.5e-06	4.2	5.4	8.2e-08	0.77	0.10	0.64	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	CD14	0.01	0.01	blup	38	0.00	3.5e-02	4.8	-5.3	9.9e-08	-0.02	0.01	0.40	FALSE
9	GTEx	Colon Transverse	TMCO6	0.15	0.06	enet	16	0.05	1.4e-03	4.6	-5.3	1.1e-07	-0.05	0.13	0.61	FALSE
6	GTEx	Cells Transformed fibroblasts	HARS2	0.04	0.01	enet	15	0.02	1.1e-02	4.4	-5.3	1.2e-07	-0.03	0.11	0.74	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	SLC4A9	0.07	0.02	blup	30	0.06	3.1e-06	4.4	-5.3	1.4e-07	0.04	0.04	0.87	FALSE
4	CommonMind	Brain Pre-frontal Cortex	PCDHA8	0.14	0.12	blup	460	0.15	6.6e-18	-4.9	-5.2	1.5e-07	-0.05	0.08	0.91	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM173	0.02	0.03	blup	7	0.03	4.6e-07	4.4	-5.2	1.5e-07	-0.55	0.07	0.92	FALSE
13	GTEx	Esophagus Muscularis	TMEM173	0.24	0.00	lasso	6	0.06	1.5e-04	4.2	-5.2	1.6e-07	-0.54	0.70	0.14	FALSE
7	GTEx	Cells Transformed fibroblasts	ZMAT2	0.04	0.02	lasso	4	0.02	2.4e-02	-4.8	-5.2	2.0e-07	0.02	0.08	0.81	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	WDR55	0.10	0.03	enet	8	0.04	3.3e-09	-4.9	-5.2	2.6e-07	0.04	0.02	0.98	FALSE
15	GTEx	Pituitary	FAM53C	0.28	0.09	lasso	5	0.02	8.2e-02	4.5	5.1	2.9e-07	0.06	0.11	0.13	FALSE