[Hub]/) : Traits : Arm fat percentage (left) :

chr12:121,194,565-125,270,773

Best TWAS P=1.48e-32 · Best GWAS P=3.26e-22 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HIP1R 0.06 0.02 lasso 6 0.04 1.9e-05 -5.7 -5.8 5.7e-09 0.01 0.18 0.02 FALSE
2 GTEx Adipose Subcutaneous CCDC92 0.23 0.04 enet 27 0.16 6.9e-13 -6.7 10.9 1.2e-27 0.48 0.13 0.86 FALSE
3 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 9.4 11.7 7.3e-32 0.87 0.02 0.97 FALSE
4 GTEx Adipose Subcutaneous RP11-380L11.4 0.08 0.06 lasso 4 0.04 1.9e-04 6.0 5.4 8.0e-08 0.58 0.15 0.83 FALSE
5 GTEx Adipose Visceral Omentum CCDC92 0.19 0.02 lasso 8 0.09 3.3e-05 9.4 11.7 1.3e-31 0.63 0.03 0.96 TRUE
6 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 7.6 11.9 1.5e-32 0.65 0.04 0.77 TRUE
7 GTEx Artery Tibial PITPNM2 0.11 0.05 lasso 4 0.04 2.7e-04 -5.6 6.1 8.8e-10 0.06 0.70 0.02 FALSE
8 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 9.4 9.2 2.2e-20 0.95 0.03 0.97 TRUE
9 GTEx Brain Hypothalamus DDX55 0.37 0.05 enet 20 0.03 7.4e-02 -3.5 5.2 2.2e-07 0.35 0.08 0.20 FALSE
10 GTEx Brain Putamen basal ganglia WDR66 0.25 0.01 enet 16 -0.01 5.6e-01 5.5 -5.7 9.7e-09 0.01 0.06 0.24 FALSE
11 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 8.5 9.0 3.3e-19 0.85 0.04 0.14 FALSE
12 GTEx Breast Mammary Tissue (Female) KDM2B 0.13 0.00 lasso 3 0.01 1.2e-01 -4.6 5.8 5.4e-09 0.10 0.05 0.14 TRUE
13 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 8.4 8.4 5.1e-17 0.89 0.04 0.26 TRUE
14 GTEx Breast Mammary Tissue (Female) C12orf65 0.06 0.00 enet 13 -0.01 6.5e-01 -3.9 -5.6 2.4e-08 -0.08 0.04 0.26 FALSE
15 GTEx Cells Transformed fibroblasts BCL7A 0.06 0.01 lasso 4 0.01 3.1e-02 5.1 -7.7 1.8e-14 -0.04 0.09 0.05 TRUE
16 GTEx Cells Transformed fibroblasts CCDC92 0.09 0.00 enet 28 0.01 3.8e-02 7.7 6.0 1.6e-09 0.40 0.07 0.26 FALSE
17 GTEx Colon Sigmoid RP11-380L11.4 0.21 0.12 lasso 3 0.08 1.1e-03 9.3 9.4 4.6e-21 0.91 0.04 0.90 FALSE
18 GTEx Colon Transverse MLXIP 0.20 0.18 enet 23 0.14 5.8e-07 6.0 5.8 5.1e-09 -0.08 1.00 0.00 FALSE
19 GTEx Colon Transverse SNRNP35 0.18 0.02 lasso 8 0.04 6.5e-03 -3.9 7.2 5.4e-13 0.15 0.08 0.07 TRUE
20 GTEx Esophagus Mucosa KDM2B 0.11 0.04 enet 22 0.10 4.1e-07 3.9 7.2 8.1e-13 0.04 0.87 0.05 FALSE
21 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 8.5 8.7 2.9e-18 0.89 0.09 0.81 FALSE
22 GTEx Esophagus Mucosa HIP1R 0.21 0.05 lasso 5 0.07 1.5e-05 4.3 7.5 5.1e-14 -0.05 0.47 0.26 TRUE
23 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 9.4 9.4 5.3e-21 0.94 0.03 0.97 FALSE
24 GTEx Heart Atrial Appendage CCDC92 0.12 0.11 enet 9 0.11 1.1e-05 6.9 9.0 3.3e-19 0.79 0.05 0.93 FALSE
25 GTEx Heart Atrial Appendage RP11-380L11.4 0.18 0.11 lasso 7 0.12 6.5e-06 9.4 10.2 1.9e-24 0.92 0.03 0.97 FALSE
26 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 8.5 10.1 3.6e-24 0.87 0.08 0.92 FALSE
27 GTEx Lung CCDC92 0.14 0.00 enet 10 0.01 1.1e-01 8.4 8.8 1.4e-18 0.18 0.18 0.11 TRUE
28 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 9.5 9.3 1.0e-20 0.94 0.03 0.97 FALSE
29 GTEx Muscle Skeletal RP11-380L11.4 0.14 0.03 lasso 8 0.03 4.0e-04 9.4 7.6 4.0e-14 0.90 0.02 0.97 FALSE
30 GTEx Nerve Tibial CCDC92 0.16 0.01 enet 6 0.04 6.7e-04 8.3 9.6 6.7e-22 0.68 0.07 0.63 FALSE
31 GTEx Nerve Tibial KNTC1 0.12 0.05 lasso 5 0.05 1.9e-04 -5.7 -6.2 6.1e-10 0.02 0.53 0.03 FALSE
32 GTEx Prostate CCDC92 0.31 0.10 enet 42 0.11 9.0e-04 8.4 7.1 1.1e-12 0.48 0.05 0.78 FALSE
33 GTEx Skin Sun Exposed Lower leg DDX55 0.13 0.05 enet 13 0.10 1.6e-08 -3.5 5.4 5.2e-08 0.07 1.00 0.00 FALSE
34 GTEx Skin Sun Exposed Lower leg CCDC92 0.11 0.00 enet 15 0.01 1.0e-01 7.7 6.6 5.2e-11 0.50 0.06 0.50 FALSE
35 GTEx Skin Sun Exposed Lower leg RP11-380L11.4 0.04 0.02 enet 15 0.02 1.9e-02 9.5 8.4 3.6e-17 0.83 0.02 0.96 FALSE
36 GTEx Testis EIF2B1 0.17 0.08 lasso 8 0.07 4.7e-04 -3.2 -5.4 7.9e-08 -0.23 0.90 0.03 FALSE
37 GTEx Thyroid CCDC92 0.06 0.03 lasso 3 0.02 1.1e-02 9.4 10.5 1.4e-25 0.89 0.04 0.94 FALSE
38 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 8.4 -9.2 2.6e-20 -0.87 0.04 0.96 FALSE
39 GTEx Thyroid ATP6V0A2 0.07 0.02 enet 9 0.02 9.8e-03 -3.9 -5.5 4.2e-08 -0.26 0.20 0.39 FALSE
40 GTEx Whole Blood DDX55 0.13 0.04 enet 13 0.06 3.3e-06 -3.5 5.6 1.9e-08 0.05 0.34 0.02 FALSE
41 METSIM Adipose ABCB9 0.04 0.03 enet 19 0.03 7.7e-05 -5.7 -7.4 1.9e-13 0.12 0.08 0.65 FALSE
42 METSIM Adipose CCDC92 0.10 0.01 bslmm 435 0.06 5.5e-10 -4.3 10.6 1.9e-26 0.62 0.18 0.82 FALSE
43 METSIM Adipose DNAH10 0.03 0.00 bslmm 475 0.01 3.2e-03 9.7 8.5 1.5e-17 0.66 0.02 0.92 FALSE
44 METSIM Adipose MORN3 0.06 0.02 lasso 10 0.04 8.7e-07 5.7 6.9 4.7e-12 0.01 0.14 0.85 FALSE
45 METSIM Adipose RP11-214K3.24 0.05 0.03 bslmm 444 0.02 2.7e-04 8.5 10.3 5.2e-25 0.73 0.04 0.93 FALSE
46 NTR Blood ZNF664 0.02 0.00 bslmm 447 0.01 6.3e-04 -5.0 -5.7 1.1e-08 -0.57 0.03 0.83 FALSE
47 YFS Blood MORN3 0.12 0.13 lasso 7 0.15 4.9e-48 5.7 5.3 9.7e-08 0.01 0.09 0.91 FALSE
48 The Cancer Genome Atlas Breast Invasive Carcinoma DNAH10 0.11 0.03 blup 99 0.05 8.2e-11 7.3 8.8 1.2e-18 0.71 0.03 0.97 FALSE
49 The Cancer Genome Atlas Colon Adenocarcinoma MLXIP 0.06 0.04 lasso 7 0.02 2.7e-02 5.8 6.0 2.4e-09 -0.07 0.02 0.93 FALSE
50 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 8.4 8.8 8.7e-19 0.93 0.02 0.73 FALSE
51 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DNAH10 0.10 0.01 blup 98 0.02 3.7e-03 9.4 5.4 6.8e-08 0.64 0.03 0.83 TRUE
52 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC92 0.06 0.04 enet 8 0.05 1.7e-06 8.6 6.3 2.8e-10 0.75 0.06 0.91 FALSE
53 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNAH10 0.07 0.03 lasso 3 0.05 7.4e-06 9.5 9.3 1.2e-20 0.80 0.02 0.98 FALSE
54 The Cancer Genome Atlas Rectum Adenocarcinoma MLXIP 0.18 0.14 lasso 4 0.13 5.1e-04 5.2 5.6 2.7e-08 -0.08 0.02 0.88 FALSE
55 The Cancer Genome Atlas Soft Tissue Sarcoma CCDC92 0.05 0.03 blup 52 0.03 5.8e-03 3.8 7.3 2.1e-13 0.91 0.04 0.68 FALSE
56 The Cancer Genome Atlas Stomach Adenocarcinoma MLXIP 0.06 0.02 blup 68 0.04 1.2e-03 5.9 7.3 1.9e-13 -0.03 0.02 0.86 TRUE
57 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 8.3 8.7 3.3e-18 0.86 0.01 0.86 FALSE
58 The Cancer Genome Atlas Thyroid Carcinoma VPS33A 0.06 0.00 enet 8 0.03 9.6e-04 4.6 -5.7 9.6e-09 0.02 0.27 0.69 FALSE
59 The Cancer Genome Atlas Thyroid Carcinoma ZNF664 0.06 0.05 enet 9 0.05 2.8e-05 9.4 -9.6 9.7e-22 -0.92 0.02 0.97 FALSE