TWAS hub - MORN3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0563	0.0188	4.4e-06	0.023	0.039	0.029	0.038	0.041	1.9e-04	1.5e-06	3.1e-05	2.0e-06	8.7e-07
2	NTR	Blood	0.0249	0.0089	1.1e-04	0.014	0.012	0.013	0.012	0.015	1.8e-05	6.3e-05	4.4e-05	5.8e-05	1.2e-05
3	YFS	Blood	0.1179	0.0202	0.0e+00	0.133	0.128	0.154	0.153	0.154	3.7e-41	1.0e-39	7.8e-48	1.1e-47	4.9e-48

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Trunk fat percentage	9.7	39.0	51.1	7.2	5.6	5.9
Body fat percentage	9.7	38.2	50.8	7.1	5.5	5.8
Exposure to tobacco smoke outside home	8.8	11.7	13.8	3.7	3.2	3.3
Mean Putamen Volume	8.7	9.9	11.9	2.7	3.2	3.5
Arm fat percentage (left)	8.4	33.6	47.7	6.9	5.0	5.3
Leg fat percentage (left)	8.2	29.6	37.1	6.1	4.9	5.2
Trunk fat mass	7.6	32.5	43.0	6.6	5.0	5.4
Leg fat percentage (right)	7.2	26.0	34.2	5.8	4.5	4.8
Whole body fat mass	7.0	29.3	39.7	6.3	4.7	5.1
Leg fat mass (left)	6.8	26.4	35.5	6.0	4.5	4.9
Mouth/teeth dental problems: Bleeding gums	6.7	8.7	11.8	3.4	2.5	2.8
Arm fat percentage (right)	6.6	26.1	37.9	6.2	4.3	4.7
Leg fat mass (right)	6.1	23.8	33.0	5.7	4.2	4.6
Age at last live birth	5.7	8.2	9.4	-3.1	-2.9	-2.6
Arm fat mass (left)	5.7	23.6	33.7	5.8	4.1	4.5
Arm fat mass (right)	5.3	21.8	31.1	5.6	3.9	4.3
Commuting to job workplace: Car/motor vehicle	5.0	5.7	7.4	1.7	2.6	2.7
Medication: Bendroflumethiazide	5.0	7.5	10.2	-2.1	-3.2	-2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.8	5.7	6.4	2.5	2.3	2.3
Waist circumference	4.5	16.6	22.5	4.7	3.5	3.9
Exposure to tobacco smoke at home	4.4	4.9	8.5	2.9	1.8	1.7
Supplements: Fish oil (including cod liver oil)	4.3	5.6	6.9	1.8	2.6	2.6
Hearing difficulty/problems: Yes	3.9	6.0	7.7	2.0	2.5	2.8
Qualifications: None of the above	3.9	8.3	10.4	2.9	2.5	3.2
Medication: Ramipril	3.9	5.0	7.2	2.7	2.0	1.9
Qualifications: College or University degree	3.8	12.0	12.2	-3.4	-3.5	-3.5
Body mass index (BMI)	3.7	15.9	23.0	4.8	3.3	3.7
Mineral and other dietary supplements	3.6	4.8	6.7	-1.6	-2.6	-2.3
Illnesses of siblings	3.4	4.8	5.6	-2.4	-1.9	-2.2
Qualifications: A levels/AS levels or equivalent	3.4	7.5	8.9	-2.8	-2.4	-3.0
Worry too long after embarrassment	3.4	5.7	8.0	2.8	2.0	2.3
Average weekly champagne plus white wine intake	3.4	4.6	6.1	-2.0	-2.0	-2.5
Ovarian Cancer	3.3	4.4	4.9	1.9	2.2	2.2
BMI	3.0	17.2	25.4	5.0	3.5	3.7
Shortness of breath walking on level ground	3.0	3.6	4.2	2.0	1.7	1.9
Blood Platelet Count	2.9	33.1	44.9	-6.7	-6.7	-3.1
Age at first live birth	2.9	5.2	6.3	-2.5	-2.1	-2.2
Hearing aid user	2.9	3.2	3.7	1.9	1.8	1.7
Pain experienced in last month	2.9	4.9	6.0	-2.4	-2.1	-2.0
Overall health rating	2.8	6.0	7.1	2.7	2.2	2.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.8	3.3	3.8	1.6	1.9	1.9
Myopia	2.8	4.0	6.4	2.5	1.6	1.7
Alzheimer’s Disease (in mother)	2.7	3.1	4.5	2.1	1.5	1.7
Alzheimer’s Disease (including proxy)	2.7	4.0	5.0	2.2	1.9	1.8
Hip circumference	2.6	11.3	16.5	4.1	2.7	3.2
Handedness (chirality/laterality): Left-handed	2.6	3.2	3.4	-1.8	-1.7	-1.8
Relative age voice broke	2.5	3.8	4.7	1.7	2.2	1.9
Ever highly irritable/argumentative for 2 days	2.5	3.0	3.4	1.6	1.8	1.9
Alcohol drinker status: Never	2.5	3.0	5.0	-2.2	-1.4	-1.4
Pulse rate, automated reading	2.4	7.8	11.4	3.4	1.9	2.9
Weight	2.3	11.1	15.9	4.0	2.7	3.2
Hearing difficulty/problems with background noise	2.2	3.5	4.3	2.0	1.4	2.1
Had menopause	2.1	2.6	3.2	1.3	1.8	1.8
Commuting to job workplace: Public transport	2.1	2.6	3.8	-0.8	-1.9	-1.8
Medication: Seretide 50 evohaler	2.0	2.3	3.2	-1.8	-1.5	-1.2
Pack years of smoking	2.0	2.9	3.9	1.7	1.3	2.0
Age at First Birth	1.9	2.8	3.1	-1.7	-1.5	-1.8
Hypothyroidism (self reported)	1.9	4.4	6.4	2.5	1.8	1.9
Financial difficulties in last 2 years	1.9	2.6	3.9	2.0	1.3	1.4
Glaucoma (self-reported)	1.9	2.3	4.9	-2.2	-0.8	-1.1
High blood pressure (siblings)	1.9	2.7	3.6	1.9	1.2	1.7
Pulse wave peak to peak time	1.9	2.2	3.0	-1.7	-1.1	-1.5
Medication: Co-codamol	1.8	2.1	2.8	1.7	1.1	1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.1	5.4	-2.3	-1.7	-2.0
Miserableness	1.8	3.1	4.0	2.0	1.5	1.8
Ever depressed for a whole week	1.8	2.3	3.9	2.0	1.3	1.1
Smoking Status	1.7	4.2	6.1	2.5	1.7	1.9
Neuroticism	1.7	4.0	7.4	2.7	1.2	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.7	3.8	4.4	-1.9	-1.8	-2.1
Medication: Levothyroxine sodium	1.7	2.9	3.4	1.9	1.7	1.5
Ever used hormone-replacement therapy (HRT)	1.6	2.0	2.3	1.5	1.3	1.3
Alcohol usually taken with meals	1.6	2.5	4.3	-2.1	-1.1	-1.4
Pulse wave Arterial Stiffness index	1.6	1.9	2.9	1.7	1.0	1.4
Migraine (self-reported)	1.6	2.0	3.0	1.1	1.7	1.3
Pack years adult smoking proportion	1.5	2.4	3.2	1.8	1.1	1.7
Number of self-reported non-cancer illnesses	1.5	2.6	5.0	2.2	1.0	1.3
Depressed Affect (Nagel 2018)	1.4	2.9	4.7	2.2	1.0	1.7
Waist Hip Ratio (WHR)	1.4	6.3	7.6	2.8	2.6	2.2
Diabetes (mother)	1.4	1.8	3.9	2.0	1.0	0.8
Ever taken oral contraceptive pill	1.4	1.6	2.0	1.0	1.4	1.4
Heel T-Score	1.3	10.1	15.9	-4.0	-2.6	-2.7
Hand grip strength (left)	1.3	3.5	5.1	-2.3	-1.6	-1.7
Stomach or abdominal pain in last month	1.3	1.6	2.6	1.6	0.9	1.1
Neuroticism score	1.3	2.7	4.9	2.2	1.0	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	4.2	-2.0	-0.2	-0.5
Eye problems/disorders: Glaucoma	1.3	1.5	3.8	-1.9	-0.2	-0.8
Frequency of depressed mood in last 2 weeks	1.2	1.7	2.8	-0.9	-1.7	-1.2
Multivitamins +/- minerals	1.2	1.6	2.0	1.4	1.1	1.2
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	3.0	-1.7	-1.1	-1.3
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	3.8	1.9	1.3	1.3
Ever had bowel cancer screening	1.2	1.4	1.5	1.2	1.1	1.2
High cholesterol (Self-reported)	1.2	2.1	2.9	1.5	1.2	1.7
Wheeze or whistling in the chest in last year	1.1	1.9	2.4	1.5	1.0	1.6
Health satisfaction	1.1	1.4	1.5	1.2	1.2	1.1
Knee pain experienced in last month	1.1	1.7	2.7	1.6	0.9	1.3
Commuting to job workplace: Cycle	1.1	1.3	3.5	1.9	0.6	0.3
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.0	1.4	0.9	1.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	2.3	0.7	1.2	1.5
Had other major operations	1.0	1.2	1.7	-1.3	-0.9	-1.1
Pulse rate	1.0	1.6	2.9	1.7	0.7	1.2
Medication: Cholesterol lowering	1.0	1.6	2.7	1.6	0.9	1.1
Birth weight of first child	1.0	1.9	3.4	-1.8	-1.0	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	1.7	1.3	1.0	1.1
Illnesses of siblings: Diabetes	1.0	1.2	1.4	1.0	1.2	1.1
Mood swings	1.0	1.9	3.1	1.8	0.9	1.3
Smoking status: Current	1.0	1.6	3.8	1.9	0.5	0.9
Wears glasses or contact lenses	1.0	1.1	2.7	-1.6	-0.5	-0.7
Ever smoked	1.0	1.7	2.7	1.6	1.2	1.1
Ever had prostate specific antigen (PSA) test	1.0	1.1	1.5	0.6	1.2	1.2
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	3.0	1.7	0.5	0.7
Reaction Time	0.9	1.7	2.4	-1.0	-1.3	-1.6
Neuroticism (2016)	0.9	1.3	2.0	1.4	0.9	1.0
Maternal smoking around birth	0.9	1.2	1.6	1.3	1.2	0.8
High blood pressure	0.9	2.5	3.3	1.8	1.4	1.5
Chronic bronchitis/emphysema (father)	0.9	1.0	1.9	1.4	0.8	0.8
Length of working week for main job	0.9	0.9	1.5	-0.6	-1.0	-1.2
Birth weight	0.9	2.0	2.5	1.4	1.6	1.3
Chronic bronchitis/emphysema (mother)	0.9	1.1	3.0	-1.7	-0.4	-0.3
Emphysema/chronic bronchitis	0.9	1.0	1.5	0.5	1.2	1.1
Medication: Blood pressure	0.9	1.5	2.5	1.6	0.9	1.1
Hypertension (Self-reported)	0.9	2.6	3.4	1.8	1.5	1.5
Medication: Gliclazide	0.9	1.1	1.8	-0.7	-1.3	-1.0
Average weekly beer plus cider intake	0.9	1.3	2.6	1.6	0.8	0.8
Vascular/heart problems diagnosed by doctor	0.9	2.5	3.3	-1.8	-1.4	-1.5
Body Mass Index (BMI) (2010)	0.8	1.1	1.3	1.1	0.9	1.1
Current tobacco smoking	0.8	1.3	3.0	1.7	0.4	0.8
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	1.8	-1.2	-0.8	-1.4
Breast cancer (self-reported)	0.8	0.9	2.1	-1.5	-0.6	-0.5
Irritability	0.8	1.3	1.6	0.9	1.3	1.2
Cardiovascular Disease	0.7	2.3	4.3	2.1	1.1	1.1
Vitamin and mineral supplements	0.7	0.9	1.4	-1.2	-0.8	-0.8
Diabetes (father)	0.7	0.9	1.6	1.3	0.6	0.8
Heart attack	0.7	0.9	1.3	1.1	0.7	0.9
Medication: Simvastatin	0.7	1.1	1.5	0.8	1.0	1.2
Medication for pain relief, constipation, heartburn	0.7	1.2	2.8	-1.7	-0.4	-0.9
Medication: Omeprazole	0.7	0.8	2.2	1.5	0.4	0.4
Supplements: Vitamin C	0.7	0.8	1.0	0.5	1.0	1.0
Medication: Paracetamol	0.7	1.1	2.1	0.1	-1.4	-1.1
Medication: Atorvastatin	0.7	0.8	1.4	1.2	0.6	0.8
Schizophrenia vs Biploar Disorder	0.6	0.8	1.4	-0.0	-1.2	-1.0
Crohns Disease (2017)	0.6	1.3	1.6	1.2	1.2	1.0
Bipolar Disorder (2011)	0.6	0.5	0.7	-0.4	-0.9	-0.9
Crohns Disease (2012)	0.6	0.9	1.0	1.0	0.9	0.9
Past tobacco smoking	0.6	1.1	2.1	-1.4	-0.9	-0.7
Fluid intelligence score	0.6	1.2	2.2	-0.5	-1.0	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.8	0.9	0.6	1.3
Depression (self-reported)	0.6	0.8	0.9	0.9	0.8	0.9
Breastfed as a baby	0.6	0.7	1.3	0.2	1.1	0.9
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.6	0.3	0.9	1.2
Forced vital capacity (FVC), Best measure	0.6	2.1	2.8	-1.7	-1.2	-1.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.1	1.4	-0.1	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.2	1.1	0.8	0.4
Supplements: Calcium	0.6	0.7	0.8	0.9	0.9	0.7
Heart disease (siblings)	0.6	0.7	0.9	0.9	0.6	0.9
Neuroticism (Nagel 2018)	0.5	1.1	1.7	1.3	0.5	1.2
Ulcerative Colitis (UC)	0.5	1.0	1.6	1.0	1.3	0.7
Coronary Artery Disease (CAD)	0.5	0.6	0.8	0.9	-0.8	-0.7
HDL Cholesterol	0.5	0.8	1.0	1.0	0.7	0.9
Lupus	0.5	0.7	1.2	-1.1	-0.6	-0.7
Systolic Blood Pressure	0.5	2.3	3.5	-0.8	-1.7	-1.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	0.9	0.5	0.9	0.9
Ever had hysterectomy (womb removed)	0.5	0.6	1.2	0.2	1.1	0.8
Impedance of leg (left)	0.5	2.4	2.9	1.3	1.7	1.6
Mouth/teeth dental problems	0.5	0.8	2.2	-1.5	-0.3	-0.4
Alcohol intake versus 10 years previously	0.5	0.7	0.9	-0.9	-0.8	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	2.6	-1.6	-0.8	-1.2
Impedance of arm (left)	0.5	2.4	3.9	2.0	1.3	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.3	1.2	0.4	0.8
Pulse wave reflection index	0.5	0.6	0.9	0.7	0.9	0.7
Blood clot in the leg (DVT)	0.5	0.7	1.3	0.4	0.8	1.1
Suffer from ‘nerves’	0.5	0.8	1.1	1.0	0.6	1.0
Leg pain on walking	0.5	0.6	0.7	-0.6	-0.8	-0.9
Illnesses of father: Heart disease	0.5	0.7	1.3	1.1	0.5	0.7
Long-standing illness, disability or infirmity	0.5	0.7	1.0	1.0	0.5	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	0.9	-0.4	-0.9	-0.6
Qualifications: nursing, teaching	0.5	0.8	1.4	-1.2	-0.4	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.4	-0.6	-0.8	-1.2
Osteoporosis (self-reported)	0.5	0.6	1.4	-1.2	-0.4	-0.4
Guilty feelings	0.5	0.8	1.6	0.8	0.4	1.2
Impedance of whole body	0.5	2.7	3.2	1.8	1.6	1.5
Irritable Bowel Disease (IBD)	0.4	1.1	1.4	1.2	1.2	0.7
Fasting Glucose	0.4	0.5	1.2	1.1	0.4	0.2
Blood Eosinophil Count	0.4	2.8	3.4	1.4	1.8	1.9
Number of treatments/medications taken	0.4	0.7	1.2	1.1	0.4	0.9
Relative age of first facial hair	0.4	0.9	1.2	0.5	1.1	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.2	1.1	0.2	0.5
Hair/balding pattern: Pattern 2	0.4	0.5	1.0	-0.2	-1.0	-0.8
Falls in the last year	0.4	0.6	1.3	0.3	0.6	1.2
Medication: Lansoprazole	0.4	0.4	0.6	0.7	0.4	0.7
Chest pain or discomfort	0.4	0.5	0.7	0.8	0.4	0.9
Family relationship satisfaction	0.4	0.4	0.7	-0.4	-0.8	-0.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.0	-0.2	-0.6	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	1.3	-1.1	-0.7	-0.6
Osteoarthritis (self-reported)	0.4	0.5	0.7	0.6	0.7	0.8
Number of operations (self-reported)	0.4	0.6	0.9	-1.0	-0.7	-0.5
Fractured/broken bones in last 5 years	0.4	0.5	0.8	-0.6	-0.9	-0.6
Major Depression (MDD)	0.3	0.4	0.9	0.9	0.5	0.3
HbA1C	0.3	0.4	0.9	0.9	0.1	0.4
Triglycerides	0.3	0.5	0.8	-0.3	-0.7	-0.9
Lung FEV1/FVC ratio	0.3	1.6	2.3	0.7	1.5	1.4
Severe depression (siblings)	0.3	0.3	0.4	0.6	0.5	0.6
Townsend deprivation index at recruitment	0.3	0.4	1.3	1.1	-0.3	0.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.5	0.4	0.6	0.7
Serious illness, injury or assault to yourself	0.3	0.3	0.4	0.4	0.6	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.9	-1.0	-0.6	-0.0
Time employed in main current job	0.3	0.3	0.6	-0.8	-0.6	-0.3
Prospective memory result	0.3	0.3	0.4	0.6	0.6	0.5
Illnesses of mother	0.3	0.3	0.5	-0.7	-0.4	-0.7
Loud music exposure frequency	0.3	0.3	0.6	-0.8	-0.6	-0.3
Medication: Paracetamol	0.3	0.5	1.1	1.0	-0.6	-0.1
Eye problems/disorders: None of the above	0.3	0.3	0.8	0.9	0.1	0.4
Medication: Ibuprofen	0.3	0.4	0.5	0.4	-0.7	-0.7
Mean time to correctly identify matches	0.3	0.5	0.5	-0.7	-0.6	-0.7
Heart disease (mother)	0.3	0.4	0.9	1.0	0.2	0.5
Medication: Aspirin	0.3	0.4	0.6	0.8	0.3	0.7
Loneliness, isolation	0.3	0.4	0.8	0.9	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	1.2	-1.1	-0.2	-0.6
Mother’s age at death	0.3	0.3	0.5	-0.7	-0.5	-0.5
Risk taking	0.3	0.5	1.1	0.1	0.5	1.1
Ulcerative Colitis	0.2	0.3	0.7	-0.8	0.6	-0.0
Blood Red Count	0.2	1.5	3.3	-1.8	0.7	0.9
Allergy or Eczema	0.2	0.4	1.1	1.1	-0.2	0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.8	0.9	-0.1	0.5
Average weekly spirits intake	0.2	0.2	0.6	0.7	-0.0	0.4
Sensitivity / hurt feelings	0.2	0.3	0.7	0.8	-0.4	0.1
Systolic blood pressure, automated reading	0.2	0.6	1.0	1.0	0.6	0.8
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	0.1	0.4	0.7
Fed-up feelings	0.2	0.4	1.1	1.1	-0.4	0.1
Supplements: Glucosamine	0.2	0.3	0.5	-0.0	0.7	0.6
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	0.7	0.0	0.5
Nervous feelings	0.2	0.5	0.9	0.9	0.4	0.6
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.9	0.9	0.0	0.0
Happiness	0.2	0.2	0.6	0.7	0.1	0.0
Medication: Amlodipine	0.2	0.3	0.7	0.8	0.5	0.2
Arm fat-free mass (right)	0.2	1.2	1.6	1.1	0.9	1.3
Number of children fathered	0.2	0.2	0.3	-0.6	0.5	0.1
Neck or shoulder pain in last month	0.2	0.3	0.6	0.8	0.4	0.5
Arm predicted mass (right)	0.2	1.0	1.3	1.0	0.8	1.1
Number of full sisters	0.2	0.2	0.3	0.5	0.4	0.4
Eye problems/disorders: Cataract	0.2	0.2	0.3	-0.1	-0.4	-0.6
Medication: Aspirin	0.2	0.2	0.4	0.6	0.2	0.6
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.4	0.4	0.4	0.6
Cholesterol lowering medication	0.2	0.3	0.7	0.3	0.4	0.8
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	0.8	0.0	0.3
Bipolar Disorder or Schizophrenia	0.1	0.3	0.8	0.9	-0.1	0.3
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	0.3	-0.5	-0.8
Schizophrenia (2018)	0.1	0.3	0.5	0.7	-0.1	0.5
Alzheimer’s Disease (in father)	0.1	0.1	0.2	-0.2	-0.4	-0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.4	0.6	-0.3	-0.5
LDL Cholesterol	0.1	0.2	0.2	-0.5	-0.4	-0.3
Rheumatoid Arthritis	0.1	0.2	0.4	-0.6	-0.4	-0.1
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.3	-0.5	0.2	0.2
Blood White Count	0.1	0.4	1.0	1.0	-0.2	0.3
Respiratory disease	0.1	0.1	0.4	-0.6	-0.2	0.1
Lung FVC	0.1	0.5	1.3	-1.1	0.4	0.1
Chronotype (morning person)	0.1	0.2	0.4	-0.3	0.6	0.3
Hair Pigment	0.1	3.8	5.3	1.4	2.0	2.3
Angina	0.1	0.2	0.5	0.7	-0.2	0.2
Medication: Metformin	0.1	0.1	0.2	0.4	0.1	0.4
Impedance of leg (right)	0.1	0.6	0.9	0.4	0.9	0.8
Leg fat-free mass (left)	0.1	0.5	1.1	1.0	0.2	0.5
Hand grip strength (right)	0.1	0.2	0.4	-0.6	-0.0	0.2
Taking other prescription medications	0.1	0.2	0.3	0.5	-0.1	0.5
Age when periods started (menarche)	0.1	0.1	0.2	-0.4	0.2	-0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.6	-0.1	0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.2	0.4	-0.3	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.5	0.6	-0.7	-0.2
Medication: Atenolol	0.1	0.1	0.2	0.4	0.3	0.2
High blood pressure (mother)	0.1	0.1	0.2	0.3	0.3	0.5
Leg predicted mass (left)	0.1	0.4	1.0	1.0	0.1	0.5
Number of incorrect matches in round	0.1	0.2	0.2	0.3	-0.4	-0.4
Forced vital capacity (FVC)	0.1	0.4	0.7	-0.8	-0.3	-0.5
Pain all over the body in last month	0.1	0.1	0.2	0.4	-0.0	-0.2
Diabetes (self-reported)	0.1	0.1	0.3	-0.2	-0.5	0.0
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.5	0.0	0.2	0.7
Trunk fat-free mass	0.1	0.8	1.0	-1.0	-0.9	-0.7
Father’s age at death	0.1	0.2	0.2	-0.5	-0.4	-0.3
Number of live births	0.1	0.1	0.2	0.5	0.4	0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.1	-1.0	-0.2	-0.6
Noisy workplace	0.1	0.1	0.3	-0.6	-0.1	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	-0.1	0.2	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.4	0.6	-0.2	-0.2
Trunk predicted mass	0.1	0.7	0.9	-1.0	-0.9	-0.6
Standing height	0.1	0.7	1.4	-1.2	-0.7	-0.5
Tense / ‘highly strung’	0.1	0.1	0.2	0.1	-0.5	-0.3
Hair/balding pattern: Pattern 4	0.1	0.3	0.3	-0.6	-0.6	-0.4
Peak expiratory flow (PEF)	0.1	0.2	0.5	-0.7	0.0	-0.2
Headache pain in last month	0.1	0.1	0.2	-0.1	0.3	0.5
Gout (self-reported)	0.1	0.1	0.2	0.3	0.4	0.4
Number of full brothers	0.1	0.1	0.1	-0.3	-0.0	-0.3
Angina (self-reported)	0.1	0.1	0.3	0.4	-0.5	-0.0
Alcohol intake frequency.	0.1	0.2	0.3	-0.4	-0.6	-0.4
Leg fat-free mass (right)	0.1	0.4	0.9	1.0	0.1	0.5
Average weekly red wine intake	0.1	0.1	0.2	0.4	0.4	0.3
Diabetes diagnosed by doctor	0.1	0.2	0.4	0.6	0.0	0.5
Friendships satisfaction	0.1	0.2	0.4	0.7	-0.0	-0.2
Medication for cholesterol	0.1	0.1	0.1	-0.3	-0.1	-0.4
Back pain experienced in last month	0.1	0.1	0.3	-0.5	0.1	0.3
Illnesses of father: None of the above (group 1)	0.1	0.2	0.4	-0.7	0.3	-0.0
Leg predicted mass (right)	0.1	0.3	0.7	0.9	0.0	0.4
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	-0.0	-0.4	-0.4
Medication: Lisinopril	0.1	0.1	0.2	-0.5	-0.3	0.2
Basal metabolic rate	0.1	0.5	0.9	0.9	0.3	0.7
Diastolic blood pressure, automated reading	0.1	0.4	0.5	0.5	0.6	0.7
Unable to work because of sickness or disability	0.1	0.2	0.2	-0.5	-0.1	0.5
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.0	-0.4	-0.2
Bipolar Disorder (2018)	0.0	0.1	0.1	0.3	-0.1	-0.3
Depression (Nagel 2018)	0.0	0.1	0.2	-0.1	-0.4	0.0
Worry (Nagel 2018)	0.0	0.1	0.2	0.4	-0.2	0.2
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.0	0.1	0.2	0.4	0.1	0.0
Schizophrenia (2014)	0.0	0.0	0.1	-0.1	-0.3	0.1
Height	0.0	0.1	0.2	-0.5	-0.2	0.0
Tanning	0.0	0.5	0.7	0.3	0.8	0.9
Medication for hormone replacement therapy	0.0	0.0	0.1	0.3	-0.1	0.1
Supplements: Zinc	0.0	0.0	0.1	0.2	-0.1	-0.2
Average weekly fortified wine intake	0.0	0.0	0.1	0.3	-0.0	0.2
Sitting height	0.0	0.1	0.2	0.4	0.3	0.3
Allergy	0.0	0.1	0.1	-0.3	0.3	-0.2
Impedance of arm (right)	0.0	0.1	0.2	0.5	-0.1	-0.2
Worrier / anxious feelings	0.0	0.1	0.2	0.4	0.1	0.3
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	0.0	0.2	0.2
Mouth/teeth dental problems: Dentures	0.0	0.0	0.0	-0.0	-0.1	-0.0
Asthma	0.0	0.1	0.2	-0.0	0.1	0.4
Lung cancer (father)	0.0	0.1	0.1	0.2	0.1	-0.4
Comparative body size at age 10	0.0	0.1	0.1	0.0	-0.3	-0.3
Medication: Allopurinol	0.0	0.0	0.1	0.3	0.0	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	0.2	-0.1	-0.1
Comparative height size at age 10	0.0	0.0	0.1	-0.0	-0.1	0.3
Had major operations	0.0	0.0	0.1	0.1	-0.1	0.3
Smoking status: Previous	0.0	0.1	0.1	0.2	0.3	0.1
Whole body fat-free mass	0.0	0.0	0.1	0.0	-0.3	-0.0
Commuting to job workplace: Walk	0.0	0.0	0.1	0.1	-0.3	-0.2
Asthma (self-reported)	0.0	0.1	0.1	-0.3	0.1	0.3
Whole body water mass	0.0	0.0	0.1	0.1	-0.3	0.0
Financial situation satisfaction	0.0	0.0	0.1	0.2	-0.0	0.3
Medication: Blood pressure	0.0	0.0	0.0	-0.1	-0.0	0.1
Illnesses of father: High blood pressure	0.0	0.0	0.0	-0.1	-0.2	-0.1
Arm fat-free mass (left)	0.0	0.2	0.4	0.4	0.3	0.6
Age started oral contraceptive pill	0.0	0.0	0.0	-0.1	0.1	-0.1
Arm predicted mass (left)	0.0	0.1	0.3	0.3	0.2	0.5

Hub : Genes

MORN3

Models

Trait associations