[Hub]/) : Traits : Arm fat mass (left) : ← →

chr7:73,425,238-78,122,616

Best TWAS P=5.18e-18 · Best GWAS P=1.16e-16 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
118	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PMS2L3	0.23	0.14	lasso	2	0.14	1.3e-04	-8.3	-8.6	5.2e-18	0.98	0.00	0.92	TRUE
40	GTEx	Breast Mammary Tissue (Female)	POM121C	0.17	-0.01	lasso	3	0.02	6.3e-02	-8.3	-7.7	1.9e-14	0.90	0.01	0.63	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DTX2P1-UPK3BP1-PMS2P11	0.18	0.09	enet	21	0.12	6.1e-15	5.8	7.2	5.9e-13	-0.10	0.00	1.00	TRUE
106	ROSMAP	Brain Pre-frontal Cortex	RSBN1L	0.09	0.07	enet	42	0.08	9.9e-11	-4.8	-7.0	3.0e-12	0.04	0.13	0.87	TRUE
30	GTEx	Brain Frontal Cortex BA9	GSAP	0.38	0.22	lasso	6	0.21	3.0e-06	5.5	-6.1	1.0e-09	-0.01	0.09	0.52	TRUE
76	GTEx	Nerve Tibial	STAG3L1	0.37	0.21	enet	34	0.22	1.2e-15	-8.3	-6.1	1.1e-09	0.83	0.00	1.00	TRUE
14	GTEx	Artery Aorta	GSAP	0.19	0.07	lasso	2	0.04	2.8e-03	5.5	-6.0	2.5e-09	-0.01	0.12	0.57	TRUE
70	GTEx	Nerve Tibial	PMS2P5	0.16	0.04	enet	34	0.08	3.5e-06	4.1	-5.8	7.0e-09	0.22	0.02	0.96	TRUE
84	GTEx	Skin Sun Exposed Lower leg	STAG3L2	0.15	0.05	enet	8	0.08	2.8e-07	4.1	-5.7	8.9e-09	0.24	0.15	0.58	TRUE
105	ROSMAP	Brain Pre-frontal Cortex	GSAP	0.36	0.27	lasso	7	0.28	1.5e-35	5.5	-5.5	3.2e-08	-0.04	0.14	0.86	TRUE
112	The Cancer Genome Atlas	Brain Lower Grade Glioma	PION	0.08	0.05	lasso	3	0.05	8.5e-07	5.5	-5.1	3.1e-07	0.01	0.00	1.00	TRUE
53	GTEx	Esophagus Mucosa	PMS2P3	0.14	0.15	lasso	2	0.14	9.7e-10	-8.3	-8.4	3.0e-17	1.00	0.00	1.00	FALSE
82	GTEx	Skin Sun Exposed Lower leg	PMS2P3	0.38	0.30	lasso	3	0.29	1.9e-24	-8.3	-8.3	7.1e-17	1.00	0.00	1.00	FALSE
46	GTEx	Cells Transformed fibroblasts	POM121C	0.15	0.06	lasso	5	0.07	1.2e-05	-8.3	-8.3	7.2e-17	0.99	0.00	1.00	FALSE
86	GTEx	Skin Sun Exposed Lower leg	STAG3L1	0.27	0.15	lasso	5	0.15	1.3e-12	-8.3	-8.3	7.5e-17	0.98	0.00	1.00	FALSE
62	GTEx	Lung	POM121C	0.13	0.10	lasso	3	0.10	7.8e-08	-8.3	-8.3	8.6e-17	0.98	0.00	1.00	FALSE
21	GTEx	Artery Tibial	STAG3L1	0.25	0.19	lasso	4	0.19	8.3e-15	-8.3	-8.3	9.2e-17	1.00	0.00	1.00	FALSE
107	ROSMAP	Brain Pre-frontal Cortex	STAG3L1	0.46	0.32	lasso	4	0.32	2.2e-42	-8.3	-8.3	1.1e-16	1.00	0.00	1.00	FALSE
108	ROSMAP	Brain Pre-frontal Cortex	GTF2IP1	0.09	0.06	lasso	3	0.05	1.7e-07	-8.3	-8.3	1.1e-16	1.00	0.00	1.00	FALSE
19	GTEx	Artery Tibial	POM121C	0.12	0.10	lasso	1	0.10	6.8e-08	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
41	GTEx	Breast Mammary Tissue (Female)	STAG3L1	0.04	0.12	lasso	1	0.04	2.9e-02	-8.3	-8.3	1.2e-16	1.00	0.00	0.96	FALSE
50	GTEx	Colon Transverse	STAG3L1	0.22	0.18	lasso	1	0.16	4.0e-08	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
55	GTEx	Esophagus Mucosa	POM121C	0.13	0.10	lasso	1	0.07	1.0e-05	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
56	GTEx	Esophagus Mucosa	STAG3L1	0.19	0.19	lasso	1	0.18	2.4e-12	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
61	GTEx	Heart Left Ventricle	POM121C	0.13	0.12	lasso	1	0.09	2.2e-05	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
81	GTEx	Skin Not Sun Exposed Suprapubic	STAG3L1	0.13	0.19	lasso	1	0.18	2.6e-10	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
99	METSIM	Adipose	POM121C	0.11	0.08	lasso	1	0.08	1.6e-11	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
102	ROSMAP	Brain Pre-frontal Cortex	PMS2P3	0.05	0.04	lasso	1	0.03	4.6e-05	-8.3	-8.3	1.2e-16	1.00	0.00	1.00	FALSE
47	GTEx	Cells Transformed fibroblasts	STAG3L1	0.22	0.17	lasso	4	0.18	2.6e-13	-8.3	-8.3	1.3e-16	0.96	0.00	1.00	FALSE
97	GTEx	Whole Blood	STAG3L1	0.08	0.06	lasso	3	0.07	2.8e-07	-8.3	-8.3	1.3e-16	1.00	0.00	1.00	FALSE
117	The Cancer Genome Atlas	Thyroid Carcinoma	POM121C	0.08	0.07	lasso	3	0.07	3.6e-07	-8.3	-8.3	1.3e-16	0.99	0.00	1.00	FALSE
65	GTEx	Muscle Skeletal	PMS2P3	0.07	0.07	lasso	2	0.06	3.8e-06	-8.3	-8.3	1.4e-16	1.00	0.00	1.00	FALSE
103	ROSMAP	Brain Pre-frontal Cortex	POM121C	0.36	0.26	lasso	7	0.27	2.8e-34	-8.3	-8.3	1.5e-16	0.99	0.00	1.00	FALSE
110	The Cancer Genome Atlas	Breast Invasive Carcinoma	POM121C	0.04	0.04	lasso	2	0.03	1.2e-07	-8.3	-8.3	1.5e-16	1.00	0.00	1.00	FALSE
38	GTEx	Breast Mammary Tissue	STAG3L1	0.16	0.15	lasso	2	0.14	8.7e-08	-8.3	-8.3	1.6e-16	0.98	0.00	1.00	FALSE
90	GTEx	Testis	TRIM73	0.20	0.21	lasso	2	0.19	6.2e-09	-8.3	-8.2	2.1e-16	1.00	0.00	1.00	FALSE
73	GTEx	Nerve Tibial	POM121C	0.22	0.14	lasso	5	0.14	6.9e-10	-8.3	-8.2	2.5e-16	0.97	0.00	1.00	FALSE
13	GTEx	Adipose Visceral Omentum	STAG3L1	0.20	0.19	lasso	3	0.17	2.3e-09	-8.3	-8.2	2.6e-16	1.00	0.00	1.00	FALSE
23	GTEx	Brain Cerebellar Hemisphere	POM121C	0.33	0.32	lasso	3	0.30	1.4e-08	-8.3	-8.2	3.0e-16	1.00	0.00	1.00	FALSE
79	GTEx	Skin Not Sun Exposed Suprapubic	PMS2P3	0.26	0.19	lasso	3	0.17	1.3e-09	-8.3	-8.2	3.4e-16	0.99	0.00	1.00	FALSE
15	GTEx	Artery Aorta	STAG3L1	0.18	0.03	lasso	4	0.08	3.9e-05	-8.3	-8.1	6.5e-16	1.00	0.00	1.00	FALSE
92	GTEx	Thyroid	POM121C	0.14	0.08	lasso	3	0.07	3.4e-06	-8.3	-8.1	6.6e-16	0.96	0.00	1.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	POM121C	0.08	0.05	lasso	2	0.04	1.1e-05	-8.3	-8.0	8.6e-16	0.99	0.00	1.00	FALSE
9	GTEx	Adipose Subcutaneous	STAG3L1	0.30	0.24	enet	24	0.27	2.4e-22	-8.3	-8.0	1.2e-15	0.92	0.00	1.00	FALSE
67	GTEx	Muscle Skeletal	TRIM73	0.08	0.05	enet	11	0.06	3.4e-06	-8.3	-7.9	1.9e-15	0.88	0.00	1.00	FALSE
49	GTEx	Colon Sigmoid	STAG3L1	0.30	0.18	lasso	4	0.18	8.5e-07	-8.3	-7.9	2.4e-15	0.97	0.00	1.00	FALSE
88	GTEx	Stomach	TRIM73	0.23	0.09	lasso	5	0.09	3.2e-05	-8.3	-7.8	4.5e-15	0.96	0.00	0.99	FALSE
42	GTEx	Cells EBV-transformed lymphocytes	STAG3L1	0.43	0.21	enet	21	0.23	3.8e-08	-8.3	-7.8	7.1e-15	0.86	0.00	1.00	FALSE
59	GTEx	Esophagus Muscularis	STAG3L1	0.30	0.15	lasso	4	0.16	4.3e-10	-8.3	-7.7	1.1e-14	0.94	0.00	1.00	FALSE
91	GTEx	Testis	STAG3L1	0.24	0.24	enet	14	0.27	1.4e-12	-8.3	-7.7	1.5e-14	0.88	0.00	1.00	FALSE
87	GTEx	Stomach	PMS2P3	0.16	0.07	lasso	5	0.09	3.7e-05	-7.5	-7.7	1.7e-14	0.91	0.00	0.99	FALSE
17	GTEx	Artery Coronary	STAG3L1	0.28	0.13	lasso	4	0.17	1.8e-06	-7.5	-7.7	1.9e-14	0.86	0.01	0.99	FALSE
4	CommonMind	Brain Pre-frontal Cortex	STAG3L1	0.23	0.14	enet	13	0.17	1.0e-19	-8.3	-7.6	2.2e-14	0.91	0.00	1.00	FALSE
51	GTEx	Esophagus Gastroesophageal Junction	STAG3L1	0.36	0.16	lasso	5	0.16	1.7e-06	-8.3	-7.6	2.4e-14	0.93	0.00	1.00	FALSE
95	GTEx	Thyroid	STAG3L1	0.36	0.24	enet	17	0.27	8.0e-21	-8.3	-7.6	3.1e-14	0.92	0.00	1.00	FALSE
5	GTEx	Adipose Subcutaneous	PMS2P3	0.15	0.12	lasso	3	0.10	9.8e-09	-7.3	-7.6	3.7e-14	0.96	0.00	1.00	FALSE
104	ROSMAP	Brain Pre-frontal Cortex	PMS2P2	0.17	0.08	enet	8	0.08	6.0e-10	-8.3	-7.6	3.8e-14	0.90	0.00	1.00	FALSE
89	GTEx	Stomach	STAG3L1	0.35	0.20	lasso	5	0.18	4.2e-09	-7.5	-7.5	4.6e-14	0.86	0.01	0.99	FALSE
44	GTEx	Cells Transformed fibroblasts	PMS2P3	0.23	0.15	lasso	6	0.15	1.4e-11	-7.3	-7.5	5.6e-14	0.94	0.00	1.00	FALSE
25	GTEx	Brain Cerebellum	POM121C	0.30	0.15	lasso	8	0.08	2.4e-03	-8.3	-7.4	1.3e-13	0.90	0.00	0.97	FALSE
93	GTEx	Thyroid	TRIM73	0.21	0.17	lasso	4	0.18	1.6e-13	-8.3	-7.4	1.4e-13	0.97	0.00	1.00	FALSE
58	GTEx	Esophagus Muscularis	TRIM73	0.12	0.07	lasso	2	0.05	3.5e-04	-7.3	-7.3	3.1e-13	0.96	0.00	0.98	FALSE
75	GTEx	Nerve Tibial	TRIM73	0.19	0.20	enet	6	0.20	6.3e-14	-8.3	-7.3	4.0e-13	0.96	0.00	1.00	FALSE
37	GTEx	Breast Mammary Tissue	PMS2P3	0.19	0.14	lasso	4	0.19	3.5e-10	-7.3	-7.2	4.4e-13	0.88	0.00	1.00	FALSE
64	GTEx	Lung	STAG3L1	0.28	0.12	enet	35	0.16	3.3e-12	-8.3	-7.2	5.7e-13	0.79	0.00	1.00	FALSE
101	METSIM	Adipose	TRIM73	0.11	0.11	lasso	5	0.12	8.6e-18	-7.3	-7.2	7.8e-13	0.95	0.01	0.99	FALSE
71	GTEx	Nerve Tibial	PMS2P3	0.29	0.13	enet	4	0.18	1.1e-12	-7.5	-7.1	1.0e-12	0.87	0.03	0.97	FALSE
8	GTEx	Adipose Subcutaneous	TRIM73	0.20	0.12	enet	26	0.12	2.0e-10	-8.3	-7.1	1.3e-12	0.82	0.00	1.00	FALSE
60	GTEx	Heart Atrial Appendage	STAG3L1	0.14	0.04	enet	12	0.04	5.0e-03	-7.3	-7.0	2.2e-12	0.76	0.00	0.95	FALSE
69	GTEx	Muscle Skeletal	STAG3L1	0.16	0.10	enet	24	0.10	3.7e-10	-8.3	-6.9	6.3e-12	0.85	0.00	1.00	FALSE
35	GTEx	Brain Nucleus accumbens basal ganglia	STAG3L1	0.29	0.09	enet	13	0.18	1.9e-05	-8.3	-6.9	7.4e-12	0.79	0.00	0.97	FALSE
7	GTEx	Adipose Subcutaneous	POM121C	0.20	0.11	enet	18	0.12	1.2e-09	-8.3	-6.8	7.9e-12	0.80	0.00	1.00	FALSE
34	GTEx	Brain Nucleus accumbens basal ganglia	TRIM73	0.34	0.16	enet	11	0.29	1.5e-08	4.9	-6.7	1.9e-11	0.82	0.00	1.00	FALSE
36	GTEx	Brain Putamen basal ganglia	PMS2P3	0.37	0.13	lasso	6	0.18	6.0e-05	-7.5	-6.6	3.8e-11	0.73	0.01	0.85	FALSE
115	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	POM121C	0.07	0.02	enet	3	0.04	5.8e-03	-8.3	-6.5	7.6e-11	0.85	0.00	0.67	FALSE
12	GTEx	Adipose Visceral Omentum	TRIM73	0.17	0.19	lasso	3	0.22	1.4e-11	-7.3	-6.4	1.2e-10	0.92	0.00	1.00	FALSE
11	GTEx	Adipose Visceral Omentum	POM121C	0.16	0.10	lasso	5	0.12	7.2e-07	4.9	-6.4	1.7e-10	0.80	0.02	0.98	FALSE
24	GTEx	Brain Cerebellar Hemisphere	TRIM73	0.35	0.28	enet	25	0.25	3.6e-07	-8.3	-6.4	1.7e-10	0.84	0.00	1.00	FALSE
63	GTEx	Lung	TRIM73	0.14	0.03	enet	8	0.06	2.9e-05	-7.3	-6.3	3.0e-10	0.79	0.00	0.99	FALSE
74	GTEx	Nerve Tibial	STAG3L2	0.36	0.09	enet	13	0.24	9.5e-17	4.1	-6.0	2.1e-09	0.25	0.03	0.97	FALSE
98	METSIM	Adipose	NCF1	0.05	0.03	blup	130	0.04	3.9e-07	4.9	5.9	2.9e-09	-0.22	0.01	0.98	FALSE
22	GTEx	Artery Tibial	FAM185BP	0.11	0.02	enet	22	0.02	1.1e-02	5.3	5.9	3.5e-09	-0.04	0.05	0.46	FALSE
29	GTEx	Brain Frontal Cortex BA9	POM121C	0.43	0.16	enet	24	0.17	3.4e-05	-8.3	-5.9	3.8e-09	0.81	0.00	0.98	FALSE
85	GTEx	Skin Sun Exposed Lower leg	TRIM73	0.13	0.08	enet	10	0.14	1.6e-11	-7.3	-5.8	5.9e-09	0.85	0.01	0.99	FALSE
113	The Cancer Genome Atlas	Brain Lower Grade Glioma	RSBN1L	0.02	0.02	blup	58	0.02	3.4e-03	-5.5	5.8	6.2e-09	-0.03	0.02	0.84	FALSE
39	GTEx	Breast Mammary Tissue (Female)	PMS2P3	0.31	0.05	enet	8	0.10	6.2e-04	-7.5	-5.8	7.8e-09	0.69	0.02	0.79	FALSE
66	GTEx	Muscle Skeletal	TMEM60	0.11	0.12	lasso	4	0.12	4.6e-12	-5.5	5.7	1.1e-08	-0.03	0.04	0.96	FALSE
100	METSIM	Adipose	TMEM60	0.10	0.07	enet	9	0.08	2.1e-12	5.6	-5.6	1.7e-08	0.00	0.01	0.98	FALSE
27	GTEx	Brain Cerebellum	GSAP	0.38	0.30	lasso	4	0.31	6.4e-10	5.6	-5.6	2.2e-08	-0.03	0.14	0.85	FALSE
31	GTEx	Brain Hippocampus	PMS2P5	0.37	0.03	enet	12	0.05	2.9e-02	4.7	-5.6	2.2e-08	0.13	0.01	0.45	FALSE
20	GTEx	Artery Tibial	TRIM73	0.10	0.00	lasso	7	0.02	5.5e-03	-8.3	-5.6	2.6e-08	0.82	0.00	0.96	FALSE
111	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM60	0.02	0.02	lasso	1	0.02	2.3e-05	5.6	-5.6	2.6e-08	0.02	0.01	0.98	FALSE
72	GTEx	Nerve Tibial	TMEM60	0.14	0.14	lasso	8	0.12	1.1e-08	-5.5	-5.6	2.7e-08	0.02	0.06	0.94	FALSE
78	GTEx	Pituitary	TMEM60	0.19	0.06	lasso	6	0.04	2.8e-02	5.1	-5.5	2.9e-08	0.02	0.05	0.87	FALSE
83	GTEx	Skin Sun Exposed Lower leg	TMEM60	0.10	0.10	lasso	3	0.09	1.4e-07	-5.5	-5.5	3.1e-08	0.03	0.04	0.96	FALSE
45	GTEx	Cells Transformed fibroblasts	TMEM60	0.25	0.20	lasso	4	0.20	1.5e-14	-5.5	-5.5	3.2e-08	0.02	0.03	0.97	FALSE
116	The Cancer Genome Atlas	Soft Tissue Sarcoma	PHTF2	0.06	0.04	blup	72	0.04	2.0e-03	5.0	-5.5	3.7e-08	0.03	0.03	0.78	FALSE
68	GTEx	Muscle Skeletal	GSAP	0.20	0.12	lasso	2	0.12	1.8e-11	5.5	-5.5	4.0e-08	-0.01	0.14	0.86	FALSE
54	GTEx	Esophagus Mucosa	TMEM60	0.06	0.04	lasso	2	0.04	1.0e-03	-5.5	-5.5	4.3e-08	0.02	0.04	0.95	FALSE
94	GTEx	Thyroid	GSAP	0.19	0.08	lasso	3	0.07	3.3e-06	5.5	-5.4	5.8e-08	-0.03	0.15	0.84	FALSE
16	GTEx	Artery Coronary	PMS2P5	0.15	-0.01	enet	13	0.08	1.4e-03	4.1	-5.4	6.4e-08	0.20	0.01	0.68	FALSE
32	GTEx	Brain Nucleus accumbens basal ganglia	PMS2P5	0.27	0.00	enet	20	0.03	6.6e-02	4.1	-5.4	7.2e-08	0.18	0.02	0.30	FALSE
57	GTEx	Esophagus Muscularis	STAG3L2	0.23	0.09	enet	33	0.15	1.9e-09	4.1	-5.4	7.2e-08	0.26	0.03	0.97	FALSE
33	GTEx	Brain Nucleus accumbens basal ganglia	POM121C	0.33	0.27	enet	11	0.25	2.7e-07	4.9	-5.4	7.3e-08	0.59	0.04	0.86	FALSE
52	GTEx	Esophagus Gastroesophageal Junction	RSBN1L-AS1	0.38	0.41	lasso	12	0.44	1.2e-17	-5.5	-5.4	8.7e-08	0.02	0.07	0.93	FALSE
3	CommonMind	Brain Pre-frontal Cortex	RSBN1L	0.09	0.09	enet	9	0.09	2.0e-11	-5.2	-5.3	1.1e-07	0.04	0.11	0.89	FALSE
6	GTEx	Adipose Subcutaneous	TMEM60	0.08	0.05	lasso	4	0.05	7.3e-05	-5.4	-5.3	1.1e-07	0.01	0.08	0.92	FALSE
28	GTEx	Brain Cerebellum	RSBN1L	0.14	0.12	lasso	2	0.13	1.3e-04	5.2	5.3	1.1e-07	0.00	0.04	0.91	FALSE
18	GTEx	Artery Tibial	PMS2P5	0.21	0.08	lasso	5	0.07	1.9e-06	4.1	-5.3	1.2e-07	0.17	0.07	0.83	FALSE
26	GTEx	Brain Cerebellum	TRIM73	0.24	0.06	enet	12	0.14	8.2e-05	-7.3	-5.2	1.5e-07	0.83	0.00	0.98	FALSE
96	GTEx	Whole Blood	TMEM60	0.05	0.04	enet	7	0.03	5.4e-04	-5.2	-5.3	1.5e-07	0.03	0.08	0.92	FALSE
114	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM60	0.02	0.03	blup	29	0.02	6.8e-03	5.6	-5.2	1.7e-07	0.03	0.01	0.83	FALSE
77	GTEx	Ovary	RHBDD2	0.55	0.00	enet	24	0.07	7.6e-03	-7.5	5.2	1.8e-07	-0.56	0.03	0.29	FALSE
80	GTEx	Skin Not Sun Exposed Suprapubic	TMEM60	0.14	0.08	lasso	4	0.03	1.4e-02	-5.5	-5.2	2.1e-07	0.01	0.05	0.92	FALSE
43	GTEx	Cells Transformed fibroblasts	PMS2P5	0.31	0.16	lasso	5	0.18	2.1e-13	4.1	-5.2	2.2e-07	0.15	0.28	0.64	FALSE
109	YFS	Blood	TMEM60	0.14	0.16	lasso	4	0.18	1.8e-55	-5.5	-5.2	2.3e-07	0.02	0.05	0.95	FALSE
10	GTEx	Adipose Visceral Omentum	TMEM60	0.20	0.13	lasso	8	0.11	2.3e-06	-5.5	-5.1	2.7e-07	0.02	0.12	0.88	FALSE
48	GTEx	Colon Sigmoid	RSBN1L	0.17	0.09	lasso	2	0.05	5.5e-03	-5.2	-5.1	2.7e-07	0.03	0.09	0.67	FALSE