[Hub]/) : Traits : Arm fat-free mass (left) :

chr17:27,200,734-30,380,381

Best TWAS P=6.06e-28 · Best GWAS P=1.19e-33 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NF1 0.06 0.01 blup 410 0.04 1.1e-05 7.29 6.4 1.7e-10 -0.20 0.95 0.00 FALSE
2 GTEx Adipose Visceral Omentum TEFM 0.12 0.02 lasso 14 0.05 1.0e-03 0.92 -5.8 5.5e-09 0.21 0.08 0.09 FALSE
3 GTEx Artery Aorta ABHD15 0.20 0.03 enet 36 0.06 2.9e-04 -4.83 -7.7 1.2e-14 0.08 0.03 0.54 TRUE
4 GTEx Artery Aorta TEFM 0.13 0.02 enet 34 0.03 5.8e-03 0.94 -6.3 2.2e-10 0.57 0.15 0.78 FALSE
5 GTEx Artery Aorta CRLF3 0.12 0.03 enet 33 0.06 3.8e-04 1.00 -7.2 4.3e-13 0.53 0.25 0.70 TRUE
6 GTEx Artery Tibial RP11-848P1.7 0.54 0.00 lasso 10 0.02 7.3e-03 -6.67 -11.0 6.1e-28 0.47 0.02 0.06 TRUE
7 GTEx Brain Cerebellar Hemisphere CRLF3 0.38 0.35 enet 26 0.35 6.0e-10 2.43 -5.7 1.1e-08 0.32 0.97 0.01 FALSE
8 GTEx Brain Cerebellum CRLF3 0.52 0.12 lasso 27 0.20 1.3e-06 -10.39 -9.1 1.2e-19 0.56 0.09 0.74 FALSE
9 GTEx Breast Mammary Tissue CRLF3 0.10 0.10 lasso 3 0.05 9.6e-04 2.95 -5.1 2.8e-07 0.31 0.09 0.62 FALSE
10 GTEx Cells EBV-transformed lymphocytes EVI2A 0.13 0.03 lasso 4 0.01 1.5e-01 7.29 -7.8 9.2e-15 0.17 0.16 0.04 FALSE
11 GTEx Cells Transformed fibroblasts OMG 0.06 0.02 lasso 2 0.01 2.5e-02 7.31 7.4 1.8e-13 -0.22 0.14 0.07 FALSE
12 GTEx Esophagus Muscularis BLMH 0.15 0.02 lasso 8 0.01 1.0e-01 -3.28 5.3 8.9e-08 -0.13 0.04 0.46 TRUE
13 GTEx Esophagus Muscularis CRLF3 0.17 0.12 lasso 6 0.18 5.1e-11 2.44 -7.2 7.1e-13 0.46 0.94 0.05 FALSE
14 GTEx Muscle Skeletal TP53I13 0.08 0.02 lasso 4 0.02 2.2e-03 -4.83 5.8 8.2e-09 -0.08 0.07 0.32 TRUE
15 GTEx Nerve Tibial CRLF3 0.38 0.16 lasso 14 0.19 3.0e-13 2.56 -6.0 1.9e-09 0.38 1.00 0.00 FALSE
16 GTEx Ovary CRLF3 0.21 0.14 lasso 4 0.11 1.0e-03 2.44 -6.1 1.3e-09 0.40 0.06 0.58 FALSE
17 GTEx Pituitary SUZ12P 0.29 0.23 lasso 9 0.32 6.0e-09 2.43 -5.9 3.0e-09 0.40 0.86 0.07 TRUE
18 GTEx Spleen EVI2A 0.22 0.12 lasso 4 0.07 8.3e-03 7.50 -7.3 2.0e-13 0.17 0.11 0.05 FALSE
19 GTEx Spleen OMG 0.41 0.10 enet 26 0.08 4.5e-03 7.31 6.7 3.0e-11 -0.23 0.64 0.03 FALSE
20 GTEx Testis CRLF3 0.26 0.19 enet 23 0.17 3.8e-08 2.60 -5.4 7.5e-08 0.38 0.99 0.00 FALSE
21 GTEx Thyroid CRLF3 0.10 0.04 enet 35 0.08 1.1e-06 2.56 -5.7 1.5e-08 0.38 0.91 0.05 FALSE
22 GTEx Whole Blood EVI2A 0.07 0.04 lasso 4 0.04 2.6e-04 7.34 -7.5 4.6e-14 0.14 0.89 0.00 FALSE
23 METSIM Adipose CTD-2349P21.5 0.02 0.00 bslmm 252 0.01 3.0e-03 -8.70 -6.6 5.0e-11 0.33 0.04 0.31 FALSE
24 METSIM Adipose NF1 0.04 0.00 blup 396 0.01 5.5e-03 7.91 7.8 7.9e-15 -0.30 0.80 0.02 FALSE
25 METSIM Adipose TEFM 0.08 0.06 blup 246 0.06 8.8e-10 -12.09 -7.5 6.6e-14 0.57 0.00 1.00 TRUE
26 YFS Blood EVI2A 0.03 0.05 lasso 4 0.04 1.0e-13 7.50 -7.5 5.8e-14 0.10 1.00 0.00 FALSE
27 YFS Blood EVI2B 0.01 0.00 blup 339 0.00 6.4e-02 -0.47 6.6 4.4e-11 -0.26 0.07 0.02 FALSE
28 The Cancer Genome Atlas Bladder Urothelial Carcinoma EVI2A 0.03 0.03 blup 37 0.03 2.3e-03 7.39 -7.3 2.5e-13 0.10 0.02 0.76 FALSE
29 The Cancer Genome Atlas Bladder Urothelial Carcinoma OMG 0.02 0.02 blup 31 0.02 3.2e-03 7.38 -7.8 8.7e-15 0.15 0.02 0.82 FALSE
30 The Cancer Genome Atlas Breast Invasive Carcinoma EVI2A 0.03 0.03 blup 38 0.03 6.9e-07 7.30 -7.6 3.1e-14 0.12 0.03 0.97 FALSE
31 The Cancer Genome Atlas Breast Invasive Carcinoma GOSR1 0.02 0.01 enet 4 0.01 1.7e-02 -6.73 6.8 7.5e-12 -0.27 0.01 0.83 FALSE
32 The Cancer Genome Atlas Breast Invasive Carcinoma OMG 0.03 0.04 lasso 1 0.04 1.1e-08 7.38 -7.4 1.5e-13 0.23 0.02 0.98 FALSE
33 The Cancer Genome Atlas Colon Adenocarcinoma LRRC37B2 0.09 0.00 enet 11 0.03 7.3e-03 3.46 -6.3 3.5e-10 0.47 0.01 0.26 TRUE
34 The Cancer Genome Atlas Esophageal Carcinoma OMG 0.09 0.09 blup 31 0.11 2.0e-04 7.46 -7.8 5.9e-15 0.18 0.02 0.91 FALSE
35 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EVI2A 0.04 0.00 blup 37 0.01 1.1e-02 7.33 -5.8 8.2e-09 0.00 0.01 0.47 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma OMG 0.02 0.02 blup 31 0.03 6.9e-04 7.43 -7.8 7.6e-15 0.17 0.02 0.89 FALSE
37 The Cancer Genome Atlas Brain Lower Grade Glioma EVI2A 0.03 0.03 blup 38 0.04 3.0e-05 7.33 -7.8 7.7e-15 0.16 0.04 0.96 FALSE
38 The Cancer Genome Atlas Liver Hepatocellular Carcinoma NF1 0.04 0.03 blup 111 0.03 1.3e-02 7.39 7.6 2.3e-14 -0.19 0.06 0.60 FALSE
39 The Cancer Genome Atlas Lung Adenocarcinoma EVI2A 0.04 0.06 blup 38 0.06 3.0e-07 7.28 -7.7 1.4e-14 0.15 0.06 0.94 FALSE
40 The Cancer Genome Atlas Lung Adenocarcinoma OMG 0.05 0.03 lasso 5 0.04 3.6e-05 7.26 -6.7 1.8e-11 0.10 0.03 0.92 FALSE
41 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EVI2A 0.03 0.03 lasso 1 0.02 2.4e-03 7.20 -7.2 6.2e-13 0.10 0.02 0.64 FALSE
42 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GOSR1 0.15 0.00 blup 56 0.04 1.1e-03 -3.33 6.0 1.4e-09 -0.35 0.04 0.19 FALSE
43 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma OMG 0.05 0.03 blup 32 0.03 5.6e-03 7.31 -7.0 2.0e-12 0.25 0.02 0.71 FALSE
44 The Cancer Genome Atlas Prostate Adenocarcinoma EVI2A 0.08 0.12 lasso 3 0.12 1.3e-12 7.91 -7.8 6.4e-15 0.12 0.02 0.98 FALSE
45 The Cancer Genome Atlas Stomach Adenocarcinoma EVI2A 0.05 0.03 enet 7 0.04 4.8e-04 3.60 -6.0 1.5e-09 0.13 0.04 0.64 FALSE
46 The Cancer Genome Atlas Stomach Adenocarcinoma SUZ12P 0.05 0.05 blup 29 0.04 5.1e-04 2.95 -5.5 4.7e-08 0.32 0.16 0.16 TRUE
47 The Cancer Genome Atlas Thyroid Carcinoma OMG 0.02 0.01 blup 32 0.02 4.8e-03 7.31 -7.8 7.6e-15 0.18 0.02 0.86 FALSE