TWAS
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Traits
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:
Genes
EVI2B
Models
#
panel
tissue
h2
h2 se
h2 P
eQTL R2
BLUP R2
ENET R2
BSLMM R2
LASSO R2
eQTL P
BLUP P
ENET P
BSLMM P
LASSO P
1
YFS
Blood
0.0071
0.0047
0.025
-0.001
0.002
-0.001
0.001
-0.001
0.99
0.064
0.67
0.12
0.68
Trait associations
Trait
Avg chi2 ratio
Avg chi2
Max chi2
1
Trait
Avg chi2 ratio
Avg chi2
Max chi2
1
Chest pain or discomfort
15.3
22.1
22.1
-4.7
Trunk predicted mass
10.9
62.3
62.3
7.9
Trunk fat-free mass
10.8
62.1
62.1
7.9
Whole body fat-free mass
10.3
58.7
58.7
7.7
Whole body water mass
10.2
57.9
57.9
7.6
Comparative height size at age 10
10.1
55.5
55.5
7.5
Arm fat-free mass (right)
9.8
50.4
50.4
7.1
Arm predicted mass (right)
9.4
48.3
48.3
7.0
Basal metabolic rate
9.2
50.8
50.8
7.1
Leg predicted mass (right)
8.8
46.8
46.8
6.8
Leg fat-free mass (right)
8.6
45.7
45.7
6.8
Arm fat-free mass (left)
8.6
43.4
43.4
6.6
Comparative body size at age 10
8.5
23.5
23.5
4.8
Leg predicted mass (left)
8.3
44.1
44.1
6.6
Leg fat-free mass (left)
8.1
42.8
42.8
6.5
Height
8.0
153.8
153.8
12.4
Arm predicted mass (left)
7.8
39.7
39.7
6.3
Qualifications: A levels/AS levels or equivalent
7.5
16.7
16.7
4.1
Number of full brothers
7.4
9.4
9.4
-3.1
Hip circumference
7.3
31.3
31.3
5.6
Shortness of breath walking on level ground
7.1
8.4
8.4
-2.9
Standing height
6.9
68.1
68.1
8.2
Blood Platelet Count
6.8
78.7
78.7
-8.9
Age at First Birth
6.7
9.8
9.8
3.1
Nervous feelings
6.5
12.2
12.2
3.5
Maternal smoking around birth
5.8
8.4
8.4
-2.9
Number of live births
5.7
8.0
8.0
-2.8
Risk taking
5.7
8.4
8.4
-2.9
Waist Hip Ratio (WHR)
5.6
25.4
25.4
-5.0
Weight
5.6
27.6
27.6
5.2
Body Mass Index (BMI) (2010)
5.4
7.4
7.4
2.7
Medication: Omeprazole
5.2
6.2
6.2
-2.5
Intelligence (Savage-Jansen 2018)
4.8
14.8
14.8
3.8
Wheeze or whistling in the chest in last year
4.7
8.4
8.4
-2.9
Verbal and Numeric Reasoning (VNR)
4.6
11.0
11.0
3.3
Relative age of first facial hair
4.6
9.4
9.4
-3.1
Supplements: Glucosamine
4.6
6.0
6.0
2.5
Medication for pain relief, constipation, heartburn
4.5
7.7
7.7
2.8
High cholesterol (Self-reported)
4.4
7.7
7.7
-2.8
Eye problems/disorders: Glaucoma
4.3
5.1
5.1
2.3
Medication: Omeprazole (e.g. Zanprol)
4.3
5.2
5.2
-2.3
Mean Putamen Volume
4.2
4.8
4.8
-2.2
Osteoarthritis (self-reported)
4.1
5.3
5.3
2.3
Supplements: Fish oil (including cod liver oil)
4.1
5.4
5.4
2.3
Stomach or abdominal pain in last month
4.0
5.0
5.0
-2.2
Medication: Paracetamol
4.0
6.7
6.7
-2.6
Number of children fathered
4.0
4.5
4.5
-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression
3.9
5.0
5.0
-2.2
Qualifications: College or University degree
3.9
12.2
12.2
3.5
Impedance of leg (right)
3.5
16.8
16.8
-4.1
Exposure to tobacco smoke outside home
3.5
4.7
4.7
-2.2
LDL Cholesterol
3.4
5.5
5.5
-2.3
Medication: Simvastatin
3.4
5.1
5.1
-2.2
Had major operations
3.4
4.0
4.0
2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)
3.4
4.0
4.0
-2.0
Financial situation satisfaction
3.4
4.2
4.2
-2.0
Bipolar Disorder (2011)
3.3
3.2
3.2
1.8
Lung FVC
3.3
16.9
16.9
-4.1
Medication: Co-codamol
3.3
3.8
3.8
2.0
Impedance of leg (left)
3.3
15.8
15.8
-4.0
Had other major operations
3.3
4.1
4.1
-2.0
Hearing difficulty/problems: Yes
3.2
4.9
4.9
-2.2
Smoking Status
3.1
7.5
7.5
-2.7
Supplements: Zinc
3.1
3.4
3.4
-1.9
Sitting height
3.1
21.9
21.9
4.7
Chronic bronchitis/emphysema (mother)
3.1
3.6
3.6
-1.9
Medication: Allopurinol
3.1
4.1
4.1
2.0
Impedance of whole body
3.1
15.8
15.8
-4.0
Fluid intelligence score
3.0
6.2
6.2
2.5
Worry (Nagel 2018)
2.8
5.8
5.8
2.4
Neck or shoulder pain in last month
2.8
4.0
4.0
-2.0
Basal cell carcinoma (self-reported)
2.8
3.3
3.3
1.8
Heart disease (siblings)
2.8
3.5
3.5
-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)
2.7
3.1
3.1
-1.8
Impedance of arm (right)
2.6
12.1
12.1
-3.5
Impedance of arm (left)
2.6
11.9
11.9
-3.5
Age at first live birth
2.6
4.7
4.7
2.2
Medication: Paracetamol
2.6
4.0
4.0
-2.0
Breast Cancer
2.5
6.0
6.0
-2.4
Ovarian Cancer
2.5
3.3
3.3
-1.8
Hearing difficulty/problems with background noise
2.5
4.0
4.0
-2.0
Qualifications: O levels/GCSEs or equivalent
2.5
3.9
3.9
2.0
HbA1C
2.4
2.7
2.7
-1.6
Sensitivity / hurt feelings
2.4
4.0
4.0
-2.0
Heart disease (mother)
2.4
3.0
3.0
-1.7
Average weekly beer plus cider intake
2.4
3.5
3.5
-1.9
Hayfever, allergic rhinitis or eczema
2.3
5.0
5.0
2.2
Alcohol intake frequency.
2.3
5.3
5.3
2.3
Alzheimer’s Disease (including proxy)
2.2
3.2
3.2
1.8
Gout (self-reported)
2.2
3.0
3.0
1.7
Ever had bowel cancer screening
2.0
2.3
2.3
-1.5
Qualifications: nursing, teaching
2.0
3.1
3.1
1.8
Number of self-reported non-cancer illnesses
2.0
3.5
3.5
-1.9
Ever smoked
2.0
3.5
3.5
-1.9
Deep venous thrombosis (DVT) (self-reported)
2.0
2.6
2.6
-1.6
Family relationship satisfaction
1.9
2.3
2.3
-1.5
Blood Red Count
1.8
17.1
17.1
-4.1
Average weekly spirits intake
1.8
2.3
2.3
-1.5
Angina
1.8
2.3
2.3
-1.5
Hypothyroidism/myxoedema (self-reported)
1.8
3.5
3.5
-1.9
Schizophrenia (2018)
1.7
3.4
3.4
-1.9
Worrier / anxious feelings
1.7
3.2
3.2
1.8
Cholesterol lowering medication
1.7
2.5
2.5
-1.6
Blood Eosinophil Count
1.6
12.0
12.0
-3.5
Allergy or Eczema
1.6
4.2
4.2
2.0
Qualifications: None of the above
1.6
3.4
3.4
-1.9
Glaucoma (self-reported)
1.6
1.9
1.9
1.4
Medication: Cholesterol lowering
1.5
2.4
2.4
-1.6
Illness, injury, bereavement, stress in last 2 years
1.5
1.8
1.8
1.3
Commuting to job workplace: Public transport
1.5
1.8
1.8
1.3
Ever had hysterectomy (womb removed)
1.4
1.6
1.6
-1.3
Medication for hormone replacement therapy
1.4
1.6
1.6
-1.3
Frequency of tenseness / restlessness in last 2 weeks
1.4
2.2
2.2
-1.5
Father’s age at death
1.4
1.9
1.9
1.4
Pulse wave reflection index
1.4
1.7
1.7
1.3
Angina (self-reported)
1.4
1.8
1.8
-1.4
Forced expiratory volume in 1-second (FEV1), predicted
1.4
2.8
2.8
1.7
Ever had stillbirth, spontaneous miscarriage or termination
1.4
1.5
1.5
-1.2
Arm fat mass (left)
1.4
5.9
5.9
2.4
Eye problems/disorders: Diabetes related eye disease
1.3
1.4
1.4
-1.2
Chronic bronchitis/emphysema (father)
1.3
1.5
1.5
-1.2
Alcohol usually taken with meals
1.3
2.0
2.0
1.4
Arm fat mass (right)
1.3
5.3
5.3
2.3
Blood clot in the leg (DVT)
1.3
1.7
1.7
-1.3
Whole body fat mass
1.3
5.3
5.3
2.3
Mineral and other dietary supplements
1.3
1.8
1.8
-1.3
Trunk fat mass
1.2
5.2
5.2
2.3
Had menopause
1.2
1.5
1.5
-1.2
Medication: Ibuprofen (e.g. Nurofen)
1.2
1.6
1.6
-1.2
Medication: Amlodipine
1.2
1.7
1.7
1.3
Number of full sisters
1.2
1.5
1.5
-1.2
Knee pain experienced in last month
1.2
1.8
1.8
1.3
Alzheimer’s Disease (in mother)
1.1
1.3
1.3
1.1
Hand grip strength (right)
1.1
2.9
2.9
1.7
Happiness
1.1
1.3
1.3
-1.1
Prospective memory result
1.1
1.3
1.3
1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage
1.1
2.4
2.4
-1.5
Diastolic blood pressure, automated reading
1.1
3.5
3.5
1.9
Leg fat mass (left)
1.1
4.3
4.3
2.1
Coronary Artery Disease (CAD)
1.0
1.2
1.2
-1.1
Hand grip strength (left)
1.0
2.7
2.7
1.7
Tinnitus: Yes, but not now, but have in the past
1.0
1.1
1.1
-1.1
Depression (self-reported)
1.0
1.1
1.1
-1.1
Medication: Lansoprazole
1.0
1.2
1.2
-1.1
Reason for reducing amount of alcohol drunk: Health precaution
1.0
1.1
1.1
-1.1
Medication: Ibuprofen
1.0
1.2
1.2
-1.1
Qualifications: NVQ or HND or HNC or equivalent
1.0
1.2
1.2
-1.1
Medication for cholesterol
1.0
1.5
1.5
1.2
Guilty feelings
1.0
1.5
1.5
-1.2
Reaction Time
0.9
1.6
1.6
1.3
Hypothyroidism (self reported)
0.9
2.1
2.1
-1.5
Type 2 Diabetes (T2D) (2018)
0.9
1.7
1.7
1.3
Relative age voice broke
0.9
1.4
1.4
-1.2
Past tobacco smoking
0.9
1.7
1.7
1.3
Leg fat mass (right)
0.9
3.5
3.5
1.9
Long-standing illness, disability or infirmity
0.9
1.4
1.4
-1.2
Friendships satisfaction
0.9
1.1
1.1
-1.0
Pain type(s) experienced in last month: Hip pain
0.9
1.1
1.1
-1.1
Medication: Lisinopril
0.9
1.1
1.1
1.1
Bipolar Disorder or Schizophrenia
0.8
1.9
1.9
-1.4
Schizophrenia vs Biploar Disorder
0.8
1.0
1.0
-1.0
Medication: Levothyroxine sodium
0.8
1.4
1.4
-1.2
Eye problems/disorders: None of the above
0.8
0.9
0.9
-0.9
Age at last live birth
0.8
1.1
1.1
1.1
Illnesses of father: None of the above (group 1)
0.8
1.0
1.0
1.0
Ulcerative Colitis
0.7
1.0
1.0
-1.0
Blood White Count
0.7
4.8
4.8
-2.2
Diabetes (mother)
0.7
0.9
0.9
0.9
Severe depression (siblings)
0.7
0.8
0.8
0.9
Current tobacco smoking
0.7
1.1
1.1
-1.1
Mouth/teeth dental problems: Dentures
0.7
1.2
1.2
-1.1
Tense / ‘highly strung’
0.7
1.1
1.1
-1.0
Hair/balding pattern: Pattern 4
0.7
1.6
1.6
1.3
Medication: Ventolin 100micrograms inhaler
0.7
0.9
0.9
-0.9
Average weekly red wine intake
0.7
1.0
1.0
-1.0
Supplements: Calcium
0.7
0.7
0.7
-0.9
Major Depression (MDD)
0.6
0.8
0.8
-0.9
Fasting Glucose
0.6
0.7
0.7
0.8
Lupus
0.6
1.0
1.0
1.0
Triglycerides
0.6
1.0
1.0
-1.0
BMI
0.6
3.4
3.4
1.9
Cardiovascular Disease
0.6
2.1
2.1
-1.4
Ever used hormone-replacement therapy (HRT)
0.6
0.8
0.8
-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks
0.6
0.8
0.8
0.9
Waist circumference
0.6
2.3
2.3
1.5
Mouth/teeth dental problems
0.6
0.9
0.9
0.9
Noisy workplace
0.6
0.8
0.8
-0.9
Illnesses of mother
0.6
0.8
0.8
0.9
Pulse wave Arterial Stiffness index
0.6
0.8
0.8
0.9
Loud music exposure frequency
0.6
0.6
0.6
0.8
Health satisfaction
0.6
0.8
0.8
-0.9
Smoking status: Current
0.6
0.9
0.9
-1.0
Ever had prostate specific antigen (PSA) test
0.6
0.6
0.6
0.8
Fractured/broken bones in last 5 years
0.6
0.7
0.7
-0.8
Systolic Blood Pressure
0.5
2.7
2.7
-1.6
Body mass index (BMI)
0.5
2.1
2.1
1.5
Alcohol intake versus 10 years previously
0.5
0.7
0.7
-0.8
Commuting to job workplace: Car/motor vehicle
0.5
0.6
0.6
-0.8
Smoking status: Previous
0.5
0.8
0.8
-0.9
Eye problems/disorders: Cataract
0.5
0.6
0.6
0.8
Average weekly champagne plus white wine intake
0.5
0.6
0.6
0.8
Miserableness
0.5
0.9
0.9
-0.9
Neuroticism (2016)
0.4
0.5
0.5
0.7
Schizophrenia (2014)
0.4
0.8
0.8
-0.9
Respiratory disease
0.4
1.0
1.0
-1.0
Systolic blood pressure, automated reading
0.4
1.2
1.2
-1.1
Medication: Metformin
0.4
0.5
0.5
-0.7
Diabetes (father)
0.4
0.5
0.5
0.7
Average weekly fortified wine intake
0.4
0.5
0.5
0.7
Qualifications: CSEs or equivalent
0.4
0.6
0.6
-0.8
Medication: Atenolol
0.4
0.5
0.5
0.7
Forced vital capacity (FVC)
0.4
1.5
1.5
1.2
Ever unenthusiastic/disinterested for a whole week
0.4
0.5
0.5
-0.7
Medication: Ramipril
0.4
0.5
0.5
-0.7
Ever highly irritable/argumentative for 2 days
0.4
0.4
0.4
-0.7
Emphysema/chronic bronchitis
0.4
0.5
0.5
-0.7
Medication: Seretide 50 evohaler
0.4
0.4
0.4
-0.7
Mean time to correctly identify matches
0.4
0.7
0.7
0.9
Overall health rating
0.4
0.9
0.9
-1.0
Vascular/heart problems diagnosed by doctor
0.4
1.0
1.0
1.0
Pain experienced in last month
0.4
0.6
0.6
0.8
Number of treatments/medications taken
0.3
0.5
0.5
-0.7
Age when periods started (menarche)
0.3
0.7
0.7
0.9
Bilateral oophorectomy (both ovaries removed)
0.3
0.3
0.3
-0.6
Heel bone mineral density (BMD) T-score, automated (left)
0.3
0.7
0.7
0.8
Multivitamins +/- minerals
0.3
0.4
0.4
-0.6
Serious illness, injury or assault of a close relative in last 2 years
0.3
0.4
0.4
0.6
Asthma
0.3
0.5
0.5
-0.7
Medication for cholesterol, blood pressure or diabetes
0.3
0.5
0.5
0.7
Birth weight
0.3
0.6
0.6
0.8
Forced vital capacity (FVC), Best measure
0.3
1.0
1.0
1.0
Migraine (self-reported)
0.3
0.3
0.3
-0.6
Suffer from ‘nerves’
0.3
0.5
0.5
0.7
Illnesses of siblings: Diabetes
0.3
0.4
0.4
0.6
Medication: Gliclazide
0.3
0.3
0.3
-0.6
Wears glasses or contact lenses
0.3
0.3
0.3
0.6
Unable to work because of sickness or disability
0.3
0.4
0.4
-0.6
Myopia
0.3
0.4
0.4
-0.6
Depressed Affect (Nagel 2018)
0.2
0.3
0.3
-0.6
Neuroticism (Nagel 2018)
0.2
0.5
0.5
0.7
Crohns Disease (2017)
0.2
0.5
0.5
0.7
Ulcerative Colitis (UC)
0.2
0.4
0.4
-0.7
Crohns Disease (2012)
0.2
0.4
0.4
0.6
Chronotype (morning person)
0.2
0.5
0.5
0.7
Other serious medical condition/disability diagnosed by doctor
0.2
0.2
0.2
-0.5
Vitamin and mineral supplements
0.2
0.2
0.2
0.5
Townsend deprivation index at recruitment
0.2
0.3
0.3
-0.6
Financial difficulties in last 2 years
0.2
0.3
0.3
-0.5
Diabetes (self-reported)
0.2
0.3
0.3
-0.5
Hair/balding pattern: Pattern 3
0.2
0.4
0.4
0.6
Forced expiratory volume in 1-second (FEV1)
0.2
0.8
0.8
0.9
Lung cancer (father)
0.2
0.2
0.2
0.5
Birth weight of first child
0.2
0.4
0.4
0.7
Leg fat percentage (right)
0.2
0.6
0.6
-0.8
Mouth/teeth dental problems: Loose teeth
0.2
0.3
0.3
-0.5
Medication: Blood pressure
0.2
0.3
0.3
0.5
Pulse rate, automated reading
0.2
0.5
0.5
-0.7
Medication: Aspirin
0.2
0.2
0.2
-0.5
Mood swings
0.2
0.3
0.3
-0.6
Mouth/teeth dental problems: Mouth ulcers
0.2
0.2
0.2
0.5
Asthma (self-reported)
0.2
0.3
0.3
-0.6
Medication: Aspirin
0.2
0.3
0.3
-0.6
Hearing aid user
0.2
0.2
0.2
-0.5
Number of operations (self-reported)
0.2
0.4
0.4
-0.6
Depression (Nagel 2018)
0.1
0.2
0.2
-0.5
Alzheimer’s Disease (in father)
0.1
0.1
0.1
0.3
Prostate Cancer
0.1
0.2
0.2
-0.4
Primary Biliary Cirrhosis
0.1
0.1
0.1
-0.3
Rheumatoid Arthritis
0.1
0.2
0.2
0.4
Type 2 Diabetes (T2D) (2012)
0.1
0.2
0.2
0.4
Heel T-Score
0.1
0.9
0.9
-1.0
Lung FEV1/FVC ratio
0.1
0.7
0.7
0.8
Neuroticism
0.1
0.2
0.2
0.4
Hair Pigment
0.1
2.1
2.1
-1.4
Tanning
0.1
0.7
0.7
-0.9
Frequency of depressed mood in last 2 weeks
0.1
0.1
0.1
-0.3
Fed-up feelings
0.1
0.1
0.1
0.3
Serious illness, injury or assault to yourself
0.1
0.1
0.1
0.4
Heart attack
0.1
0.2
0.2
0.4
Allergy
0.1
0.2
0.2
-0.5
Pain all over the body in last month
0.1
0.1
0.1
-0.4
Hayfever/allergic rhinitis (self-reported)
0.1
0.1
0.1
0.3
Neuroticism score
0.1
0.2
0.2
0.5
Frequency of tiredness / lethargy in last 2 weeks
0.1
0.2
0.2
-0.4
Forced expiratory volume in 1-second (FEV1), Best measure
0.1
0.4
0.4
0.7
Exposure to tobacco smoke at home
0.1
0.2
0.2
-0.4
Breastfed as a baby
0.1
0.1
0.1
-0.4
Mouth/teeth dental problems: Bleeding gums
0.1
0.2
0.2
-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria
0.1
0.1
0.1
-0.3
Hypertension (Self-reported)
0.1
0.3
0.3
-0.5
Illnesses of father: Heart disease
0.1
0.2
0.2
-0.4
Handedness (chirality/laterality): Left-handed
0.1
0.1
0.1
0.3
Diabetes diagnosed by doctor
0.1
0.1
0.1
0.3
Commuting to job workplace: Walk
0.1
0.1
0.1
-0.3
Medication: Blood pressure
0.1
0.2
0.2
-0.4
Illnesses of father: High blood pressure
0.1
0.1
0.1
0.3
Leg fat percentage (left)
0.1
0.3
0.3
-0.5
Commuting to job workplace: Cycle
0.1
0.2
0.2
0.4
Alcohol drinker status: Previous
0.1
0.1
0.1
0.3
Bipolar Disorder (2018)
0.0
0.0
0.0
0.1
Irritable Bowel Disease (IBD)
0.0
0.0
0.0
-0.2
HDL Cholesterol
0.0
0.0
0.0
0.1
Pack years adult smoking proportion
0.0
0.0
0.0
0.1
Trunk fat percentage
0.0
0.0
0.0
0.0
Taking other prescription medications
0.0
0.0
0.0
-0.2
High blood pressure
0.0
0.1
0.1
-0.2
Diverticular disease/diverticulitis (self-reported)
0.0
0.0
0.0
-0.1
High blood pressure (mother)
0.0
0.0
0.0
-0.0
Number of incorrect matches in round
0.0
0.0
0.0
0.2
Hair/balding pattern: Pattern 2
0.0
0.0
0.0
-0.1
Heel bone mineral density (BMD) T-score, automated (right)
0.0
0.0
0.0
-0.1
Illnesses of siblings
0.0
0.1
0.1
0.3
Arm fat percentage (right)
0.0
0.1
0.1
-0.3
Time employed in main current job
0.0
0.0
0.0
0.0
Falls in the last year
0.0
0.0
0.0
-0.2
Pulse rate
0.0
0.1
0.1
0.3
Length of working week for main job
0.0
0.1
0.1
0.2
Seen doctor (GP) for nerves, anxiety, tension or depression
0.0
0.0
0.0
-0.1
Peak expiratory flow (PEF)
0.0
0.0
0.0
-0.0
Headache pain in last month
0.0
0.0
0.0
0.1
High blood pressure (siblings)
0.0
0.0
0.0
0.2
Body fat percentage
0.0
0.0
0.0
-0.2
Worry too long after embarrassment
0.0
0.0
0.0
-0.0
Pulse wave peak to peak time
0.0
0.1
0.1
-0.2
Leg pain on walking
0.0
0.0
0.0
-0.2
Supplements: Vitamin C
0.0
0.0
0.0
-0.2
Arm fat percentage (left)
0.0
0.0
0.0
0.1
Loneliness, isolation
0.0
0.0
0.0
0.2
Back pain experienced in last month
0.0
0.0
0.0
0.0
Breast cancer (self-reported)
0.0
0.1
0.1
-0.2
Osteoporosis (self-reported)
0.0
0.0
0.0
0.1
Ever taken oral contraceptive pill
0.0
0.0
0.0
-0.1
Mother’s age at death
0.0
0.1
0.1
0.2
Tinnitus: Yes, now most or all of the time
0.0
0.0
0.0
-0.1
Medication: Bendroflumethiazide
0.0
0.0
0.0
-0.2
Medication: Atorvastatin
0.0
0.0
0.0
-0.2
Alcohol drinker status: Never
0.0
0.0
0.0
-0.2
Irritability
0.0
0.0
0.0
-0.1
Age started oral contraceptive pill
0.0
0.0
0.0
-0.2
Ever depressed for a whole week
0.0
0.0
0.0
-0.1
Heart attack/myocardial infarction (self-reported)
0.0
0.0
0.0
0.2
Pack years of smoking
0.0
0.0
0.0
0.0