[Hub]/) : Traits : Arm predicted mass (left) : ← →

chr12:109,591,369-113,517,494

Best TWAS P=1.64e-16 · Best GWAS P=7.92e-22 conditioned to 0.345

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	HECTD4	0.06	0.00	enet	15	0.02	1.0e-02	3.6	-6.7	1.6e-11	0.65	0.06	0.84	FALSE
2	GTEx	Adrenal Gland	PPTC7	0.13	-0.01	lasso	6	0.00	3.4e-01	5.5	6.6	4.1e-11	-0.26	0.04	0.16	TRUE
3	GTEx	Artery Tibial	VPS29	0.05	0.03	lasso	3	0.02	5.9e-03	5.8	5.8	6.6e-09	-0.11	0.06	0.77	FALSE
4	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	-8.4	-8.2	1.6e-16	0.78	0.02	0.92	TRUE
5	GTEx	Brain Cerebellum	HECTD4	0.25	-0.01	enet	24	0.06	7.7e-03	1.4	-5.1	3.1e-07	0.42	0.06	0.71	FALSE
6	GTEx	Breast Mammary Tissue (Male)	RP3-462E2.3	0.12	0.03	lasso	7	0.04	4.0e-02	3.7	5.4	5.7e-08	-0.39	0.02	0.06	FALSE
7	GTEx	Breast Mammary Tissue (Female)	VPS29	0.10	-0.01	lasso	2	0.02	1.0e-01	-5.1	6.5	6.5e-11	-0.34	0.03	0.18	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	ARPC3	0.13	0.09	lasso	4	0.04	2.0e-02	5.6	-5.6	2.7e-08	0.04	0.06	0.62	FALSE
9	GTEx	Cells Transformed fibroblasts	VPS29	0.09	0.13	lasso	3	0.13	9.8e-10	5.8	5.5	3.1e-08	-0.09	0.04	0.96	FALSE
10	GTEx	Colon Transverse	FAM109A	0.21	0.00	lasso	4	0.01	1.3e-01	5.7	-6.2	4.2e-10	0.41	0.06	0.06	FALSE
11	GTEx	Esophagus Mucosa	VPS29	0.14	0.13	lasso	6	0.13	3.0e-09	5.1	5.4	5.8e-08	-0.07	0.10	0.90	FALSE
12	GTEx	Esophagus Muscularis	VPS29	0.08	0.04	lasso	4	0.03	9.0e-03	5.1	5.2	2.1e-07	-0.07	0.10	0.67	FALSE
13	GTEx	Muscle Skeletal	VPS29	0.06	0.06	lasso	3	0.05	4.3e-06	5.8	5.7	1.1e-08	-0.09	0.04	0.96	FALSE
14	GTEx	Muscle Skeletal	IFT81	0.08	0.08	lasso	5	0.07	1.7e-07	5.6	5.7	1.3e-08	-0.04	0.02	0.98	FALSE
15	GTEx	Muscle Skeletal	ANAPC7	0.08	0.01	lasso	3	0.00	1.1e-01	5.0	5.7	1.4e-08	-0.07	0.03	0.76	FALSE
16	GTEx	Nerve Tibial	HECTD4	0.05	0.01	enet	6	0.01	3.6e-02	6.3	-6.4	1.5e-10	0.41	0.22	0.46	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	VPS29	0.06	0.01	lasso	3	0.01	6.9e-02	5.5	6.0	1.5e-09	-0.07	0.06	0.52	FALSE
18	GTEx	Skin Sun Exposed Lower leg	ARPC3	0.13	0.15	lasso	3	0.15	1.9e-12	5.5	-5.5	3.4e-08	0.05	0.08	0.92	FALSE
19	GTEx	Skin Sun Exposed Lower leg	VPS29	0.05	0.04	lasso	6	0.03	1.0e-03	4.6	5.2	2.0e-07	-0.10	0.11	0.69	FALSE
20	GTEx	Skin Sun Exposed Lower leg	ALDH2	0.10	0.09	enet	13	0.13	6.7e-11	3.5	-6.6	5.0e-11	0.62	0.86	0.14	FALSE
21	GTEx	Spleen	VPS29	0.24	0.01	enet	14	0.04	2.9e-02	4.8	5.3	1.2e-07	-0.02	0.05	0.41	FALSE
22	GTEx	Testis	ARPC3	0.16	0.16	lasso	3	0.14	7.5e-07	5.5	-5.5	3.7e-08	0.05	0.08	0.92	FALSE
23	GTEx	Thyroid	BRAP	0.07	0.02	lasso	7	0.03	1.1e-03	3.6	5.8	5.4e-09	-0.54	0.32	0.48	FALSE
24	GTEx	Thyroid	VPS29	0.07	0.01	lasso	5	0.01	8.9e-02	5.4	5.8	6.3e-09	-0.11	0.05	0.54	FALSE
25	GTEx	Whole Blood	GPN3	0.19	0.20	lasso	4	0.19	1.9e-17	5.4	-5.5	4.0e-08	0.10	0.11	0.88	FALSE
26	METSIM	Adipose	GPN3	0.05	0.04	enet	17	0.04	1.1e-06	5.3	-5.1	3.1e-07	0.01	0.14	0.86	FALSE
27	NTR	Blood	ALDH2	0.06	0.01	blup	222	0.02	4.3e-08	4.7	6.4	1.8e-10	-0.43	0.88	0.12	FALSE
28	NTR	Blood	GPN3	0.03	0.01	blup	236	0.02	2.7e-06	5.0	-6.3	2.5e-10	0.12	0.10	0.89	FALSE
29	YFS	Blood	GLTP	0.05	0.01	enet	14	0.04	1.5e-13	4.6	5.6	2.8e-08	-0.08	0.02	0.98	FALSE
30	YFS	Blood	SH2B3	0.05	0.01	enet	22	0.02	3.3e-07	3.6	-6.6	5.4e-11	0.64	0.67	0.32	FALSE
31	YFS	Blood	TRAFD1	0.04	0.02	lasso	2	0.01	2.9e-05	-4.3	-5.5	4.2e-08	0.55	0.09	0.85	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	VPS29	0.02	0.02	lasso	5	0.03	4.6e-06	5.4	5.8	6.9e-09	-0.07	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Colon Adenocarcinoma	ALDH2	0.07	0.03	lasso	4	0.06	3.9e-04	3.6	-5.8	8.5e-09	0.44	0.02	0.84	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACAD10	0.02	0.02	lasso	3	0.01	7.0e-03	6.2	6.2	5.9e-10	-0.50	0.01	0.88	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	VPS29	0.06	0.06	enet	7	0.06	2.1e-07	5.5	5.7	1.4e-08	-0.06	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ERP29	0.11	0.03	blup	25	0.05	5.0e-03	3.6	5.4	6.9e-08	-0.60	0.01	0.75	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	CUX2	0.08	0.01	blup	95	0.02	1.3e-03	4.7	6.4	1.5e-10	-0.15	0.17	0.06	TRUE
38	The Cancer Genome Atlas	Thyroid Carcinoma	RAD9B	0.10	0.06	enet	5	0.06	1.2e-06	5.5	5.5	3.5e-08	-0.05	0.01	0.99	FALSE