[Hub]/) : Traits : Trunk fat percentage :

chr12:120,044,549-125,270,773

Best TWAS P=2.67e-36 · Best GWAS P=4.99e-24 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC92 0.09 0.01 bslmm 438 0.03 3.1e-04 8.8 -5.2 1.5e-07 -0.67 0.11 0.86 TRUE
2 CommonMind Brain Pre-frontal Cortex HIP1R 0.06 0.02 lasso 6 0.04 1.9e-05 -4.7 -5.2 2.1e-07 0.01 0.18 0.02 FALSE
3 GTEx Adipose Subcutaneous CCDC92 0.23 0.04 enet 27 0.16 6.9e-13 -7.6 11.6 3.9e-31 0.48 0.17 0.83 FALSE
4 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 9.7 12.3 8.7e-35 0.87 0.02 0.97 FALSE
5 GTEx Adipose Subcutaneous RP11-380L11.4 0.08 0.06 lasso 4 0.04 1.9e-04 6.8 6.3 2.7e-10 0.58 0.14 0.84 FALSE
6 GTEx Adipose Visceral Omentum CCDC92 0.19 0.02 lasso 8 0.09 3.3e-05 9.8 12.5 7.1e-36 0.63 0.05 0.94 FALSE
7 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 8.3 12.6 2.7e-36 0.65 0.04 0.74 TRUE
8 GTEx Artery Aorta P2RX4 0.20 0.03 enet 28 0.05 1.6e-03 -3.6 -5.2 2.4e-07 0.04 0.12 0.60 TRUE
9 GTEx Artery Tibial SIRT4 0.30 0.14 lasso 8 0.14 4.3e-11 -6.0 -6.0 1.8e-09 -0.04 0.01 0.99 FALSE
10 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 9.7 9.7 3.1e-22 0.95 0.05 0.95 TRUE
11 GTEx Artery Tibial RP11-347I19.8 0.16 0.09 enet 26 0.10 1.7e-08 3.9 -5.4 6.1e-08 0.09 0.99 0.00 FALSE
12 GTEx Brain Cerebellar Hemisphere WDR66 0.28 0.05 lasso 8 0.04 3.6e-02 -4.5 -5.7 1.2e-08 -0.03 0.08 0.19 FALSE
13 GTEx Brain Cerebellum SIRT4 0.48 -0.01 enet 32 0.24 9.2e-08 -6.0 -5.8 9.1e-09 -0.10 0.02 0.88 FALSE
14 GTEx Brain Putamen basal ganglia WDR66 0.25 0.01 enet 16 -0.01 5.6e-01 5.9 -6.4 1.8e-10 0.01 0.06 0.23 FALSE
15 GTEx Breast Mammary Tissue SIRT4 0.19 0.16 lasso 6 0.16 1.4e-08 -6.0 -5.8 5.1e-09 -0.03 0.01 0.99 FALSE
16 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 8.8 9.2 3.9e-20 0.85 0.04 0.14 FALSE
17 GTEx Breast Mammary Tissue (Female) KDM2B 0.13 0.00 lasso 3 0.01 1.2e-01 -4.3 5.8 6.4e-09 0.10 0.04 0.30 TRUE
18 GTEx Breast Mammary Tissue (Female) SIRT4 0.03 0.03 lasso 1 0.05 1.0e-02 -5.7 -5.7 1.3e-08 -0.05 0.02 0.63 FALSE
19 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 8.8 8.8 1.9e-18 0.89 0.04 0.24 TRUE
20 GTEx Breast Mammary Tissue (Female) C12orf65 0.06 0.00 enet 13 -0.01 6.5e-01 -3.7 -5.5 4.5e-08 -0.08 0.04 0.28 FALSE
21 GTEx Cells Transformed fibroblasts BCL7A 0.06 0.01 lasso 4 0.01 3.1e-02 5.4 -8.4 2.9e-17 -0.04 0.09 0.05 TRUE
22 GTEx Cells Transformed fibroblasts CCDC92 0.09 0.00 enet 28 0.01 3.8e-02 7.6 6.3 3.0e-10 0.40 0.07 0.24 FALSE
23 GTEx Colon Sigmoid RP11-380L11.4 0.21 0.12 lasso 3 0.08 1.1e-03 9.7 9.8 6.9e-23 0.91 0.05 0.87 FALSE
24 GTEx Colon Transverse MLXIP 0.20 0.18 enet 23 0.14 5.8e-07 5.9 5.8 7.3e-09 -0.08 1.00 0.00 FALSE
25 GTEx Colon Transverse SNRNP35 0.18 0.02 lasso 8 0.04 6.5e-03 -3.3 6.8 1.2e-11 0.15 0.08 0.07 TRUE
26 GTEx Esophagus Mucosa KDM2B 0.11 0.04 enet 22 0.10 4.1e-07 3.5 7.0 2.2e-12 0.04 0.91 0.01 FALSE
27 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 8.9 9.1 1.0e-19 0.89 0.09 0.81 FALSE
28 GTEx Esophagus Mucosa HIP1R 0.21 0.05 lasso 5 0.07 1.5e-05 4.5 7.3 3.4e-13 -0.05 0.47 0.26 TRUE
29 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 9.8 9.8 1.7e-22 0.94 0.05 0.95 FALSE
30 GTEx Heart Atrial Appendage CCDC92 0.12 0.11 enet 9 0.11 1.1e-05 7.1 9.3 2.0e-20 0.79 0.06 0.92 FALSE
31 GTEx Heart Atrial Appendage RP11-380L11.4 0.18 0.11 lasso 7 0.12 6.5e-06 9.8 10.5 1.3e-25 0.92 0.03 0.96 FALSE
32 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 8.9 10.7 1.5e-26 0.87 0.12 0.88 FALSE
33 GTEx Lung SIRT4 0.11 0.06 lasso 8 0.01 3.8e-02 -6.0 -5.9 2.8e-09 -0.03 0.01 0.99 FALSE
34 GTEx Lung CCDC92 0.14 0.00 enet 10 0.01 1.1e-01 9.0 9.2 3.7e-20 0.18 0.18 0.11 TRUE
35 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 9.8 9.7 3.1e-22 0.94 0.04 0.96 FALSE
36 GTEx Muscle Skeletal RSRC2 0.06 0.03 enet 7 0.04 9.6e-05 -3.0 -5.9 3.9e-09 -0.03 0.25 0.48 FALSE
37 GTEx Muscle Skeletal RP11-380L11.4 0.14 0.03 lasso 8 0.03 4.0e-04 9.7 8.3 9.9e-17 0.90 0.02 0.97 FALSE
38 GTEx Muscle Skeletal RP11-347I19.8 0.08 0.06 lasso 4 0.06 2.4e-06 3.8 -5.2 2.2e-07 0.07 0.95 0.01 FALSE
39 GTEx Nerve Tibial SIRT4 0.23 0.21 lasso 5 0.20 4.6e-14 -5.6 -6.0 1.9e-09 -0.03 0.01 0.99 FALSE
40 GTEx Nerve Tibial CCDC92 0.16 0.01 enet 6 0.04 6.7e-04 8.6 10.1 6.1e-24 0.68 0.07 0.64 FALSE
41 GTEx Nerve Tibial KNTC1 0.12 0.05 lasso 5 0.05 1.9e-04 -5.7 -6.3 2.6e-10 0.02 0.53 0.03 FALSE
42 GTEx Pancreas SIRT4 0.40 0.37 lasso 7 0.37 1.8e-16 -5.7 -6.0 1.6e-09 -0.03 0.01 0.99 TRUE
43 GTEx Pancreas RP11-347I19.8 0.12 0.00 enet 13 0.00 2.9e-01 3.9 -5.4 7.1e-08 0.05 0.09 0.11 FALSE
44 GTEx Prostate CCDC92 0.31 0.10 enet 42 0.11 9.0e-04 8.8 7.9 2.9e-15 0.48 0.06 0.70 FALSE
45 GTEx Skin Sun Exposed Lower leg CCDC92 0.11 0.00 enet 15 0.01 1.0e-01 7.6 6.9 5.7e-12 0.50 0.07 0.44 FALSE
46 GTEx Skin Sun Exposed Lower leg AC084018.1 0.29 0.15 enet 22 0.21 3.5e-17 3.9 -5.2 2.5e-07 0.10 1.00 0.00 FALSE
47 GTEx Skin Sun Exposed Lower leg RP11-380L11.4 0.04 0.02 enet 15 0.02 1.9e-02 9.9 8.9 6.5e-19 0.83 0.02 0.96 FALSE
48 GTEx Stomach SIRT4 0.14 0.14 enet 8 0.09 3.1e-05 -5.7 -5.6 2.8e-08 -0.04 0.01 0.99 FALSE
49 GTEx Stomach RP11-347I19.8 0.22 0.09 lasso 7 0.11 4.2e-06 4.1 -5.5 5.1e-08 0.08 0.95 0.01 FALSE
50 GTEx Thyroid CCDC92 0.06 0.03 lasso 3 0.02 1.1e-02 9.7 10.9 1.3e-27 0.89 0.04 0.93 FALSE
51 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 8.8 -9.8 1.1e-22 -0.87 0.07 0.93 FALSE
52 METSIM Adipose ABCB9 0.04 0.03 enet 19 0.03 7.7e-05 -4.7 -7.0 2.7e-12 0.12 0.08 0.65 FALSE
53 METSIM Adipose CCDC92 0.10 0.01 bslmm 435 0.06 5.5e-10 -4.9 11.3 1.7e-29 0.62 0.17 0.83 FALSE
54 METSIM Adipose DNAH10 0.03 0.00 bslmm 475 0.01 3.2e-03 10.1 9.1 6.3e-20 0.66 0.01 0.93 FALSE
55 METSIM Adipose MORN3 0.06 0.02 lasso 10 0.04 8.7e-07 6.2 7.2 9.0e-13 0.01 0.02 0.98 FALSE
56 METSIM Adipose RP11-214K3.24 0.05 0.03 bslmm 444 0.02 2.7e-04 8.9 10.5 7.0e-26 0.73 0.05 0.91 FALSE
57 METSIM Adipose SIRT4 0.06 0.04 enet 20 0.03 6.6e-06 -6.0 -5.2 1.9e-07 -0.05 0.01 0.99 FALSE
58 NTR Blood MORN3 0.02 0.01 lasso 4 0.01 1.2e-05 5.7 5.6 2.6e-08 0.02 0.02 0.98 FALSE
59 NTR Blood ZNF664 0.02 0.00 bslmm 447 0.01 6.3e-04 -5.2 -6.5 8.1e-11 -0.57 0.02 0.86 FALSE
60 YFS Blood MORN3 0.12 0.13 lasso 7 0.15 4.9e-48 6.2 5.9 3.2e-09 0.01 0.02 0.98 FALSE
61 The Cancer Genome Atlas Breast Invasive Carcinoma DNAH10 0.11 0.03 blup 99 0.05 8.2e-11 7.0 9.7 4.0e-22 0.71 0.05 0.95 FALSE
62 The Cancer Genome Atlas Breast Invasive Carcinoma SIRT4 0.06 0.06 lasso 4 0.05 2.8e-11 -6.0 -5.9 3.3e-09 -0.04 0.00 1.00 FALSE
63 The Cancer Genome Atlas Colon Adenocarcinoma LOC338799 0.06 0.03 blup 31 0.05 5.2e-04 4.3 -5.3 9.4e-08 0.09 0.01 0.21 FALSE
64 The Cancer Genome Atlas Colon Adenocarcinoma MLXIP 0.06 0.04 lasso 7 0.02 2.7e-02 5.8 5.9 3.4e-09 -0.07 0.02 0.92 FALSE
65 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 8.8 9.2 2.7e-20 0.93 0.02 0.73 FALSE
66 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC92 0.06 0.04 enet 8 0.05 1.7e-06 9.0 6.3 3.2e-10 0.75 0.06 0.91 FALSE
67 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNAH10 0.07 0.03 lasso 3 0.05 7.4e-06 9.8 9.4 7.6e-21 0.80 0.02 0.97 FALSE
68 The Cancer Genome Atlas Lung Adenocarcinoma LOC338799 0.04 0.02 blup 29 0.04 3.5e-05 4.1 -5.5 5.0e-08 0.07 0.02 0.49 FALSE
69 The Cancer Genome Atlas Rectum Adenocarcinoma MLXIP 0.18 0.14 lasso 4 0.13 5.1e-04 5.2 5.6 2.7e-08 -0.08 0.02 0.88 FALSE
70 The Cancer Genome Atlas Soft Tissue Sarcoma CCDC92 0.05 0.03 blup 52 0.03 5.8e-03 4.4 7.9 3.4e-15 0.91 0.04 0.63 FALSE
71 The Cancer Genome Atlas Stomach Adenocarcinoma MLXIP 0.06 0.02 blup 68 0.04 1.2e-03 5.9 7.3 2.1e-13 -0.03 0.02 0.84 TRUE
72 The Cancer Genome Atlas Stomach Adenocarcinoma SIRT4 0.10 0.06 blup 37 0.08 1.3e-06 -5.7 -5.2 1.8e-07 -0.04 0.01 0.99 FALSE
73 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 8.6 9.3 1.9e-20 0.86 0.01 0.88 FALSE
74 The Cancer Genome Atlas Thyroid Carcinoma VPS33A 0.06 0.00 enet 8 0.03 9.6e-04 4.5 -5.8 8.6e-09 0.02 0.07 0.92 FALSE
75 The Cancer Genome Atlas Thyroid Carcinoma ZNF664 0.06 0.05 enet 9 0.05 2.8e-05 9.7 -9.7 2.3e-22 -0.92 0.03 0.97 FALSE