[Hub]/) : Traits : Trunk fat mass : ← →

chr22:37,528,576-39,663,066

Best TWAS P=1.1e-17 · Best GWAS P=5.77e-18 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	BAIAP2L2	0.11	0.03	lasso	5	0.04	1.8e-04	6.7	-7.9	2.8e-15	-0.75	0.03	0.86	TRUE
2	GTEx	Adipose Subcutaneous	TMEM184B	0.08	0.08	lasso	4	0.07	1.0e-06	5.4	-6.5	6.5e-11	-0.57	0.82	0.13	FALSE
3	GTEx	Artery Aorta	C22orf23	0.10	0.01	enet	24	0.02	1.6e-02	2.4	5.7	1.1e-08	0.34	0.25	0.10	FALSE
4	GTEx	Artery Aorta	PLA2G6	0.10	0.02	enet	9	0.02	4.5e-02	5.3	7.8	5.5e-15	0.67	0.07	0.64	FALSE
5	GTEx	Artery Aorta	TMEM184B	0.17	0.07	enet	34	0.03	1.2e-02	7.8	-7.5	5.3e-14	-0.67	0.07	0.68	FALSE
6	GTEx	Artery Aorta	AL021977.1	0.13	0.00	enet	17	0.01	8.7e-02	7.9	-8.2	2.6e-16	-0.73	0.03	0.76	TRUE
7	GTEx	Brain Cortex	TMEM184B	0.29	0.12	lasso	7	0.09	1.6e-03	7.8	-8.0	1.1e-15	-0.90	0.01	0.89	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	PLA2G6	0.28	0.17	enet	13	0.18	1.3e-06	-6.5	7.5	4.5e-14	0.70	0.26	0.59	FALSE
9	GTEx	Cells Transformed fibroblasts	PLA2G6	0.23	0.09	lasso	9	0.10	9.9e-08	7.2	7.8	5.7e-15	0.83	0.63	0.37	FALSE
10	GTEx	Cells Transformed fibroblasts	MAFF	0.08	0.08	lasso	3	0.06	2.2e-05	6.3	-5.5	4.4e-08	-0.71	0.34	0.26	FALSE
11	GTEx	Cells Transformed fibroblasts	TMEM184B	0.17	0.16	lasso	5	0.14	2.1e-10	5.4	-6.1	1.2e-09	-0.51	1.00	0.00	FALSE
12	GTEx	Cells Transformed fibroblasts	AL021977.1	0.08	0.08	enet	7	0.06	2.4e-05	5.4	-5.5	4.3e-08	-0.48	0.82	0.10	FALSE
13	GTEx	Colon Sigmoid	TMEM184B	0.20	0.03	lasso	4	-0.01	5.4e-01	5.4	-5.5	4.9e-08	-0.42	0.10	0.16	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	PLA2G6	0.28	0.24	lasso	5	0.23	1.1e-08	-6.5	7.0	2.2e-12	0.65	0.76	0.12	FALSE
15	GTEx	Esophagus Mucosa	PLA2G6	0.22	0.02	lasso	6	0.04	1.9e-03	7.2	7.7	1.9e-14	0.80	0.06	0.93	FALSE
16	GTEx	Esophagus Muscularis	PLA2G6	0.12	0.00	enet	18	0.01	1.4e-01	7.1	6.6	4.1e-11	0.61	0.08	0.35	FALSE
17	GTEx	Esophagus Muscularis	TMEM184B	0.11	0.01	enet	10	0.06	2.7e-04	3.7	-6.5	1.1e-10	-0.60	0.26	0.20	TRUE
18	GTEx	Muscle Skeletal	DMC1	0.13	0.01	enet	17	0.04	3.3e-05	6.7	6.4	1.9e-10	0.58	0.03	0.83	FALSE
19	GTEx	Nerve Tibial	PLA2G6	0.34	0.08	lasso	8	0.11	2.9e-08	-6.5	7.5	8.2e-14	0.74	0.90	0.10	TRUE
20	GTEx	Nerve Tibial	MAFF	0.14	0.06	lasso	3	0.05	1.2e-04	8.6	-8.5	1.7e-17	-0.99	0.01	0.99	TRUE
21	GTEx	Nerve Tibial	TMEM184B	0.16	0.12	lasso	7	0.14	3.6e-10	5.4	-5.8	7.9e-09	-0.44	0.99	0.01	TRUE
22	GTEx	Nerve Tibial	AL021977.1	0.16	0.05	lasso	3	0.07	9.3e-06	5.4	-6.6	4.8e-11	-0.60	0.52	0.45	FALSE
23	GTEx	Skin Sun Exposed Lower leg	BAIAP2L2	0.09	0.09	lasso	4	0.09	5.5e-08	6.7	-7.2	7.5e-13	-0.77	0.27	0.73	TRUE
24	GTEx	Thyroid	PLA2G6	0.34	0.20	lasso	5	0.18	4.5e-14	-6.5	7.2	4.5e-13	0.68	1.00	0.00	FALSE
25	GTEx	Thyroid	TMEM184B	0.19	0.16	lasso	7	0.18	1.0e-13	5.4	-7.1	1.5e-12	-0.66	1.00	0.00	FALSE
26	GTEx	Thyroid	AL021977.1	0.20	0.11	lasso	6	0.12	2.7e-09	5.4	-7.2	5.5e-13	-0.65	0.96	0.03	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	ANKRD54	0.03	0.00	blup	397	0.01	2.2e-02	2.0	-5.3	1.4e-07	-0.27	0.19	0.06	FALSE
28	YFS	Blood	CSNK1E	0.04	0.00	enet	50	0.01	5.7e-05	0.4	-5.3	1.4e-07	-0.22	0.04	0.05	FALSE
29	YFS	Blood	TMEM184B	0.09	0.07	enet	38	0.09	7.8e-28	5.3	-5.3	1.1e-07	-0.52	1.00	0.00	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ANKRD54	0.20	0.06	lasso	1	0.06	3.0e-07	-5.4	-5.4	8.7e-08	-0.17	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLA2G6	0.05	0.01	blup	76	0.01	7.7e-02	8.6	8.6	1.1e-17	0.85	0.01	0.84	TRUE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TMEM184B	0.03	0.03	lasso	2	0.03	7.7e-05	5.3	-5.5	3.6e-08	-0.44	0.24	0.16	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	BAIAP2L2	0.05	0.01	blup	52	0.03	3.7e-04	3.0	-5.5	3.3e-08	-0.44	0.08	0.25	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	PLA2G6	0.03	0.02	lasso	2	0.03	6.5e-04	7.7	7.7	1.8e-14	0.82	0.09	0.18	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM184B	0.03	0.04	lasso	2	0.04	1.6e-04	5.4	-5.4	6.1e-08	-0.44	0.14	0.24	FALSE