[Hub]/) : Traits : Trunk fat-free mass : ← →

chr5:136,723,696-141,087,689

Best TWAS P=1.25e-14 · Best GWAS P=5.72e-18 conditioned to 0.00987

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBE2D2	0.05	0.02	enet	6	0.03	4.4e-04	5.3	7.7	1.3e-14	0.91	0.01	0.97	TRUE
28	ROSMAP	Brain Pre-frontal Cortex	WNT8A	0.05	0.01	blup	300	0.03	1.0e-04	-2.4	-6.7	2.2e-11	0.00	0.14	0.78	TRUE
16	GTEx	Esophagus Muscularis	DNAJC18	0.22	0.10	lasso	6	0.13	3.2e-08	5.0	6.5	5.9e-11	0.59	0.55	0.12	TRUE
20	GTEx	Nerve Tibial	HARS	0.07	0.01	enet	16	0.04	1.1e-03	-4.6	5.8	5.3e-09	-0.04	0.08	0.84	TRUE
13	GTEx	Esophagus Gastroesophageal Junction	DNAJC18	0.17	0.01	lasso	10	0.04	2.0e-02	5.1	7.5	7.3e-14	0.77	0.06	0.68	FALSE
39	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	BRD8	0.12	0.07	lasso	4	0.05	1.2e-03	7.0	-6.7	2.7e-11	0.00	0.00	0.98	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	DNAJC18	0.26	0.09	lasso	2	0.12	9.7e-05	5.0	6.7	2.8e-11	0.77	0.04	0.84	FALSE
31	YFS	Blood	CXXC5	0.01	0.00	bslmm	244	0.01	2.6e-03	8.6	-6.6	3.5e-11	-0.48	0.02	0.72	FALSE
15	GTEx	Esophagus Mucosa	TMEM173	0.10	0.03	enet	20	0.10	1.8e-07	8.6	-6.4	1.6e-10	-0.39	0.04	0.81	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC18	0.09	0.10	bslmm	260	0.10	2.5e-12	4.6	6.4	1.7e-10	0.64	1.00	0.00	FALSE
12	GTEx	Colon Transverse	DNAJC18	0.37	-0.01	lasso	5	0.01	1.1e-01	5.0	6.3	3.7e-10	0.59	0.06	0.07	FALSE
7	GTEx	Artery Tibial	PROB1	0.06	0.09	enet	10	0.08	5.9e-07	5.0	-6.1	8.5e-10	-0.62	0.79	0.16	FALSE
24	GTEx	Spleen	DNAJC18	0.30	0.13	lasso	5	0.20	6.5e-06	5.0	6.1	9.1e-10	0.77	0.10	0.65	FALSE
17	GTEx	Esophagus Muscularis	TMEM173	0.24	0.00	lasso	6	0.06	1.5e-04	4.9	-6.0	1.7e-09	-0.55	0.70	0.14	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM173	0.02	0.03	blup	7	0.03	4.6e-07	5.0	-6.0	2.7e-09	-0.56	0.07	0.92	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	PROB1	0.12	0.09	lasso	6	0.10	7.7e-13	5.0	-5.7	9.6e-09	-0.62	1.00	0.00	FALSE
26	GTEx	Vagina	PURA	0.52	0.05	enet	51	0.09	3.6e-03	5.1	-5.6	1.9e-08	-0.13	0.06	0.10	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FAM53C	0.05	0.02	bslmm	291	0.03	4.1e-04	7.3	5.6	2.0e-08	0.03	0.04	0.89	FALSE
44	The Cancer Genome Atlas	Thyroid Carcinoma	DNAJC18	0.08	0.10	blup	23	0.10	3.7e-10	4.8	5.6	2.2e-08	0.62	0.50	0.50	FALSE
40	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DNAJC18	0.06	0.02	blup	23	0.02	9.5e-03	5.0	5.6	2.5e-08	0.60	0.02	0.46	FALSE
23	GTEx	Skin Sun Exposed Lower leg	WDR55	0.04	0.01	enet	10	0.01	2.8e-02	-4.5	-5.6	2.6e-08	0.01	0.09	0.78	FALSE
27	METSIM	Adipose	PROB1	0.04	0.02	enet	23	0.02	2.9e-04	4.6	-5.5	3.0e-08	-0.57	0.92	0.01	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	KDM3B	0.07	0.01	blup	307	0.03	1.0e-04	4.9	-5.5	3.4e-08	-0.09	0.22	0.64	FALSE
6	GTEx	Artery Tibial	TMEM173	0.24	0.14	lasso	3	0.13	1.2e-10	5.1	-5.4	6.9e-08	-0.43	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	MGC29506	0.01	0.00	blup	24	0.00	3.6e-02	5.0	-5.4	6.9e-08	-0.58	0.01	0.40	FALSE
37	The Cancer Genome Atlas	Esophageal Carcinoma	SPATA24	0.08	0.08	blup	25	0.08	1.5e-03	4.7	5.4	7.2e-08	0.60	0.04	0.56	FALSE
14	GTEx	Esophagus Mucosa	DNAJC18	0.22	0.17	lasso	2	0.16	5.1e-11	5.0	5.4	7.3e-08	0.58	1.00	0.00	FALSE
9	GTEx	Cells Transformed fibroblasts	CD14	0.09	0.05	lasso	4	0.06	2.7e-05	-3.9	-5.4	7.4e-08	-0.01	0.20	0.70	FALSE
11	GTEx	Colon Transverse	TMCO6	0.15	0.06	enet	16	0.05	1.4e-03	4.4	-5.4	7.5e-08	-0.05	0.14	0.52	FALSE
22	GTEx	Pituitary	FAM53C	0.28	0.09	lasso	5	0.02	8.2e-02	4.7	5.4	7.9e-08	0.06	0.11	0.08	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PCDHA2	0.04	0.03	blup	478	0.03	5.0e-05	-4.7	-5.3	9.3e-08	-0.05	0.08	0.91	FALSE
21	GTEx	Ovary	DNAJC18	0.33	0.24	lasso	3	0.21	7.1e-06	5.0	5.3	9.3e-08	0.59	0.08	0.09	FALSE
18	GTEx	Lung	PROB1	0.15	0.12	lasso	11	0.10	2.2e-08	5.0	-5.3	1.3e-07	-0.59	0.98	0.01	FALSE
32	YFS	Blood	TMCO6	0.01	0.00	blup	329	0.01	4.1e-03	-4.5	-5.3	1.3e-07	0.02	0.09	0.87	FALSE
41	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SPATA24	0.03	0.02	blup	24	0.03	2.8e-03	4.6	5.3	1.3e-07	0.59	0.03	0.26	FALSE
10	GTEx	Cells Transformed fibroblasts	DNAJC18	0.28	0.14	lasso	5	0.11	1.4e-08	5.0	5.3	1.5e-07	0.59	0.99	0.00	FALSE
43	The Cancer Genome Atlas	Stomach Adenocarcinoma	SLC23A1	0.04	0.02	blup	28	0.03	4.3e-03	5.2	-5.2	1.5e-07	-0.50	0.01	0.71	FALSE
19	GTEx	Muscle Skeletal	DNAJC18	0.44	0.33	lasso	7	0.34	5.5e-34	5.0	5.2	1.7e-07	0.60	1.00	0.00	FALSE
42	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DNAJC18	0.07	0.09	blup	24	0.09	1.9e-04	5.0	5.2	1.7e-07	0.60	0.11	0.67	FALSE
25	GTEx	Thyroid	DNAJC18	0.38	0.26	lasso	4	0.26	1.5e-19	5.0	5.2	1.8e-07	0.58	1.00	0.00	FALSE
4	CommonMind	Brain Pre-frontal Cortex	SPATA24	0.05	0.03	lasso	3	0.04	1.4e-05	4.9	5.2	2.0e-07	0.53	0.54	0.03	FALSE
5	GTEx	Artery Aorta	TMEM173	0.35	0.16	enet	5	0.15	9.8e-09	5.1	-5.2	2.0e-07	-0.45	0.99	0.00	FALSE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DNAJC18	0.03	0.02	blup	22	0.02	6.9e-03	5.0	5.2	2.1e-07	0.60	0.03	0.44	FALSE
36	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DNAJC18	0.06	0.05	lasso	2	0.04	7.3e-03	5.0	5.2	2.4e-07	0.59	0.01	0.60	FALSE
45	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM173	0.04	0.04	lasso	3	0.04	2.1e-04	5.2	-5.2	2.4e-07	-0.46	0.14	0.46	FALSE