TWAS hub - SPATA24

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0510	0.0250	3.5e-04	0.028	0.033	0.032	0.033	0.039	2.2e-04	6.3e-05	7.0e-05	5.6e-05	1.4e-05
2	GTEx	Esophagus Gastroesophageal Junction	0.2130	0.0910	4.7e-03	-0.008	NA	0.004	NA	-0.005	9.5e-01	NA	2.3e-01	NA	5.1e-01
3	GTEx	Esophagus Mucosa	0.0620	0.0310	4.8e-03	0.025	NA	0.023	NA	0.024	8.0e-03	NA	1.0e-02	NA	8.9e-03
4	GTEx	Heart Left Ventricle	0.2533	0.0792	1.7e-06	0.206	NA	0.136	NA	0.166	3.1e-11	NA	1.0e-07	NA	3.6e-09
5	GTEx	Muscle Skeletal	0.0587	0.0364	9.6e-03	0.023	NA	0.003	NA	0.007	2.4e-03	NA	1.7e-01	NA	6.7e-02
6	ROSMAP	Brain Pre-frontal Cortex	0.1099	0.0358	9.3e-06	0.021	0.031	0.046	0.040	0.052	8.3e-04	7.0e-05	1.3e-06	5.8e-06	2.7e-07
7	TCGA	Esophageal Carcinoma	0.0810	0.0520	2.2e-03	0.075	0.081	0.069	NA	0.062	2.1e-03	1.5e-03	3.3e-03	NA	4.9e-03
8	TCGA	Glioblastoma Multiforme	0.3580	0.1790	4.9e-03	0.021	0.072	0.079	NA	0.043	7.7e-02	3.3e-03	2.2e-03	NA	1.9e-02
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0211	0.0169	9.8e-03	0.005	0.013	0.013	NA	0.011	8.6e-02	1.3e-02	1.1e-02	NA	1.7e-02
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0450	0.0321	8.7e-05	0.038	0.035	0.024	NA	0.029	3.5e-05	6.7e-05	8.0e-04	NA	2.8e-04
11	TCGA	Lung Adenocarcinoma	0.0283	0.0169	2.5e-05	0.037	0.038	0.030	NA	0.033	3.5e-05	2.6e-05	1.9e-04	NA	8.8e-05
12	TCGA	Lung Squamous Cell Carcinoma	0.0155	0.0114	5.5e-03	0.017	0.012	0.013	NA	0.012	4.5e-03	1.3e-02	1.2e-02	NA	1.2e-02
13	TCGA	Ovarian Serous Cystadenocarcinoma	0.0260	0.0190	7.2e-03	0.025	0.032	0.031	NA	0.027	8.0e-03	2.8e-03	3.3e-03	NA	5.6e-03
14	TCGA	Prostate Adenocarcinoma	0.0206	0.0138	1.5e-03	0.027	0.031	0.029	NA	0.027	6.4e-04	3.2e-04	4.4e-04	NA	7.0e-04
15	TCGA	Stomach Adenocarcinoma	0.0310	0.0270	8.2e-03	0.024	0.021	0.012	NA	0.019	7.2e-03	1.1e-02	4.2e-02	NA	1.5e-02
16	TCGA	Thyroid Carcinoma	0.0500	0.0380	5.4e-04	0.032	0.023	0.023	NA	0.034	4.2e-04	2.2e-03	2.2e-03	NA	2.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Hair/balding pattern: Pattern 2	8.2	10.5	16.9	-4.1	-1.4	-2.6	-3.7	-3.4	-2.3	-3.7	-2.1	-2.3	-3.5	-3.5	-3.5	-3.6	-3.8	-3.8	-2.8
Overall health rating	7.5	16.2	22.3	-4.6	-2.7	-3.8	-4.5	-4.2	-3.2	-4.6	-2.4	-3.3	-3.9	-4.5	-4.2	-4.7	-4.6	-4.3	-3.8
Fasting Glucose	5.9	7.0	10.0	2.8	1.6	2.7	2.8	2.7	3.1	2.8	-0.2	2.9	2.5	2.9	3.2	2.7	2.7	2.6	2.8
Financial situation satisfaction	5.8	7.2	11.9	-3.3	-2.1	-2.9	-2.7	-2.4	-1.5	-3.3	0.4	-1.8	-2.3	-3.2	-3.5	-3.3	-3.3	-2.9	-2.0
Angina	5.7	7.5	10.4	-3.2	-1.8	-2.0	-2.9	-2.8	-2.6	-3.1	-1.4	-2.6	-2.7	-3.1	-3.1	-3.1	-3.0	-2.9	-2.5
Had menopause	5.7	7.1	12.9	-2.8	-1.6	-2.5	-2.6	-2.9	-3.6	-2.5	-1.9	-3.0	-2.6	-2.7	-2.3	-2.6	-2.4	-2.4	-3.5
Angina (self-reported)	5.6	7.4	10.8	-3.3	-1.7	-1.9	-2.9	-2.8	-2.6	-3.1	-1.3	-2.6	-2.7	-3.1	-3.0	-3.1	-3.0	-2.9	-2.5
Age at First Birth	4.4	6.5	9.4	2.8	1.2	2.9	2.6	2.6	1.9	3.1	1.1	1.9	2.6	2.9	3.1	3.0	2.9	2.8	2.3
Systolic Blood Pressure	4.2	21.2	30.8	-5.6	-2.2	-5.4	-5.0	-4.8	-3.3	-5.2	-2.7	-2.9	-4.9	-5.0	-5.3	-5.0	-5.4	-5.3	-3.8
Supplements: Fish oil (including cod liver oil)	4.2	5.5	7.1	-2.3	-0.9	-2.0	-2.5	-2.5	-2.4	-2.6	-1.9	-2.2	-2.7	-2.5	-2.2	-2.5	-2.5	-2.6	-2.5
Illnesses of siblings	4.1	5.8	8.8	3.0	1.8	2.8	2.2	2.3	2.2	2.7	-0.1	2.1	2.3	2.7	2.9	2.6	2.6	2.5	2.1
Unable to work because of sickness or disability	4.1	5.3	7.5	-2.5	-2.5	-2.1	-2.4	-2.4	-1.5	-2.7	-0.9	-1.9	-2.3	-2.6	-2.6	-2.7	-2.7	-2.5	-1.9
Heart disease (siblings)	4.1	5.0	6.4	-2.5	-0.9	-2.0	-2.5	-2.5	-2.3	-2.4	-1.4	-2.1	-2.2	-2.5	-2.2	-2.5	-2.4	-2.2	-2.4
High blood pressure (siblings)	3.9	5.6	10.1	-3.2	-1.0	-2.8	-2.3	-2.2	-2.0	-2.7	-0.3	-1.7	-2.5	-2.6	-3.0	-2.5	-2.7	-2.7	-1.9
Pulse rate, automated reading	3.9	12.5	24.3	-4.0	-1.4	-4.9	-3.8	-3.4	-2.3	-4.2	-1.3	-2.1	-3.5	-3.9	-4.1	-4.1	-4.1	-4.0	-2.9
Migraine (self-reported)	3.8	4.8	6.9	-1.5	-2.5	-2.3	-2.6	-2.4	-1.9	-2.1	-2.1	-1.2	-2.2	-2.2	-1.8	-2.2	-2.4	-2.4	-2.6
Health satisfaction	3.6	4.7	6.6	-2.3	-1.3	-2.1	-2.4	-2.1	-1.4	-2.6	-0.8	-1.9	-2.3	-2.5	-2.5	-2.5	-2.6	-2.5	-1.8
Maternal smoking around birth	3.4	5.0	6.3	-1.9	-2.1	-2.2	-2.3	-2.3	-1.9	-2.5	-2.1	-2.4	-2.4	-2.3	-2.0	-2.5	-2.3	-2.3	-2.1
Medication: Atenolol	3.4	4.2	6.1	-2.2	-1.7	-1.9	-2.3	-2.1	-1.2	-2.4	-1.1	-1.2	-2.2	-2.3	-2.4	-2.3	-2.5	-2.5	-1.8
Father’s age at death	3.4	4.6	6.2	0.8	1.9	1.7	2.4	2.4	2.3	2.2	1.9	2.4	2.5	2.3	2.0	2.2	2.3	2.4	2.2
Commuting to job workplace: Cycle	3.3	4.0	10.4	3.2	1.5	2.0	2.0	1.6	0.7	2.5	-0.2	0.9	1.7	2.3	2.7	2.4	2.4	2.2	1.1
Ovarian Cancer	3.2	4.2	11.5	1.8	3.4	2.1	1.9	1.9	1.8	2.1	0.2	1.8	2.0	2.2	2.3	2.0	2.1	2.2	1.9
Trunk fat-free mass	3.2	18.6	29.0	5.2	1.9	4.6	4.6	4.2	3.0	5.4	2.3	3.3	4.4	4.7	5.0	5.3	4.8	4.6	3.7
Trunk predicted mass	3.2	18.3	28.5	5.2	1.9	4.5	4.6	4.2	3.0	5.3	2.2	3.3	4.4	4.7	5.0	5.2	4.8	4.5	3.6
Mother’s age at death	3.1	3.9	8.8	2.1	3.0	2.1	1.8	1.6	1.8	1.9	-0.7	1.5	1.8	2.2	2.6	1.8	2.2	2.2	1.4
Commuting to job workplace: Public transport	3.1	3.6	4.8	2.0	1.2	1.5	2.2	2.1	1.4	2.2	1.9	1.7	2.0	2.0	1.7	2.2	2.1	2.0	1.9
Arm predicted mass (left)	3.1	15.6	24.4	4.2	1.3	4.2	4.4	4.0	2.6	4.9	2.5	2.9	4.1	4.3	4.7	4.8	4.5	4.3	3.4
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	7.7	1.6	2.8	1.7	1.7	1.7	1.5	1.9	0.1	2.4	1.7	1.9	1.9	1.9	1.7	1.7	1.4
Medication: Co-codamol	3.0	3.4	5.4	-1.8	-2.0	-1.6	-1.9	-1.9	-1.5	-2.1	-1.2	-1.5	-2.0	-1.9	-2.3	-2.0	-2.0	-2.0	-1.7
Qualifications: CSEs or equivalent	3.0	4.0	5.7	-2.0	-1.6	-1.8	-2.3	-2.1	-1.2	-2.3	-1.3	-2.1	-2.0	-2.2	-2.0	-2.4	-2.2	-2.1	-1.8
Medication: Allopurinol	3.0	4.0	7.2	-2.7	-0.1	-2.2	-2.2	-1.9	-1.4	-2.4	-1.4	-1.3	-2.1	-2.2	-2.2	-2.4	-2.3	-2.2	-1.6
Arm predicted mass (right)	3.0	15.1	24.4	4.3	1.2	4.0	4.3	4.0	2.5	4.9	2.4	2.8	4.0	4.3	4.6	4.9	4.4	4.2	3.3
Medication: Aspirin	3.0	3.9	8.6	-2.9	-1.3	-1.5	-2.0	-1.7	-1.9	-2.2	-0.1	-1.4	-2.0	-2.3	-2.5	-2.1	-2.3	-2.2	-1.5
Pulse wave peak to peak time	2.9	3.5	5.3	1.8	0.4	1.6	2.3	2.1	1.0	2.1	2.2	1.4	2.1	1.9	1.6	2.1	2.1	2.1	1.8
Medication: Atorvastatin	2.8	3.5	6.0	-2.5	-1.4	-1.1	-2.3	-1.8	-0.8	-2.2	-1.5	-0.9	-1.9	-1.9	-2.4	-2.2	-2.3	-2.1	-1.3
Sensitivity / hurt feelings	2.7	4.6	8.8	-1.0	-3.0	-1.5	-2.2	-2.2	-2.7	-2.2	-1.1	-2.7	-2.2	-2.3	-2.0	-2.3	-2.1	-2.1	-2.0
Arm fat-free mass (right)	2.7	13.8	21.4	4.0	1.2	3.9	4.1	3.8	2.5	4.6	2.5	2.7	3.9	4.0	4.3	4.6	4.2	4.0	3.2
Arm fat-free mass (left)	2.7	13.7	21.4	4.0	1.2	4.0	4.1	3.8	2.5	4.6	2.3	2.8	3.9	4.0	4.3	4.6	4.2	4.0	3.2
Diverticular disease/diverticulitis (self-reported)	2.6	3.1	4.6	1.5	2.1	1.4	1.8	2.0	1.4	2.0	1.0	1.6	1.6	1.9	1.8	2.0	1.8	1.7	1.9
Sitting height	2.5	17.6	29.6	5.4	2.1	4.7	4.3	4.0	3.5	4.9	1.6	3.5	4.4	4.6	4.8	4.7	4.6	4.6	3.6
Birth weight	2.5	5.5	8.5	2.0	0.8	2.1	2.9	2.4	2.0	2.6	2.1	1.8	2.5	2.6	2.4	2.7	2.7	2.7	2.4
Leg pain on walking	2.5	3.1	5.3	-1.4	-0.2	-1.3	-2.3	-2.2	-1.2	-2.0	-2.1	-1.4	-1.9	-1.9	-1.0	-2.1	-2.0	-1.9	-1.9
Medication: Aspirin	2.5	3.2	6.8	-2.6	-1.0	-1.3	-1.8	-1.6	-1.8	-2.1	-0.2	-1.4	-1.8	-2.1	-2.2	-2.0	-2.1	-2.0	-1.4
Whole body fat-free mass	2.5	14.4	22.6	4.4	1.5	4.1	4.0	3.7	2.7	4.8	1.9	2.9	3.9	4.2	4.5	4.6	4.2	4.0	3.2
Whole body water mass	2.5	14.5	22.8	4.5	1.6	4.1	4.0	3.7	2.7	4.8	1.9	2.8	3.9	4.2	4.5	4.7	4.2	4.0	3.2
Rheumatoid Arthritis	2.4	3.2	4.0	-1.3	-1.9	-1.8	-1.8	-1.9	-1.7	-1.9	-1.2	-1.7	-2.0	-1.9	-2.0	-1.9	-1.9	-1.9	-1.8
Nervous feelings	2.4	4.6	6.8	-0.9	-0.4	-1.7	-2.5	-2.5	-1.8	-2.5	-2.2	-1.9	-2.6	-2.3	-2.0	-2.4	-2.5	-2.6	-2.2
Basal cell carcinoma (self-reported)	2.4	2.8	4.4	1.7	0.9	1.9	1.9	1.9	1.5	2.0	0.7	1.3	1.5	1.9	1.6	2.1	1.9	1.7	1.7
HbA1C	2.3	2.5	5.0	1.0	-0.2	0.9	2.2	1.7	1.3	1.9	1.0	1.5	1.8	1.7	1.6	1.9	1.9	1.8	1.6
Basal metabolic rate	2.3	12.6	19.7	4.0	1.2	3.9	3.8	3.5	2.5	4.4	1.9	2.6	3.7	3.9	4.2	4.3	4.0	3.8	3.1
Bipolar Disorder (2011)	2.2	2.2	5.5	1.1	1.0	0.0	1.8	1.8	1.6	1.5	2.3	2.1	1.7	1.4	0.8	1.6	1.3	1.4	0.0
Chronic bronchitis/emphysema (father)	2.2	2.6	5.3	-1.0	-1.0	-1.4	-1.4	-2.0	-2.2	-1.5	-1.4	-2.2	-1.7	-1.6	-1.1	-1.5	-1.3	-1.4	-2.3
Hip circumference	2.2	9.4	13.0	2.1	0.4	3.4	3.4	3.4	2.4	3.6	2.5	2.5	3.5	3.3	3.4	3.5	3.5	3.5	3.1
Impedance of arm (left)	2.2	10.2	15.4	-3.1	-1.8	-2.8	-3.7	-3.5	-2.0	-3.9	-2.8	-2.9	-3.4	-3.4	-3.5	-3.9	-3.5	-3.3	-2.9
Fed-up feelings	2.1	3.7	5.7	-0.7	-2.4	-1.4	-2.1	-2.0	-1.8	-1.9	-2.1	-2.1	-2.2	-1.9	-1.6	-1.9	-2.0	-2.1	-2.0
Frequency of tenseness / restlessness in last 2 weeks	2.1	3.2	4.5	-0.4	-1.7	-0.7	-2.0	-1.9	-2.0	-1.9	-1.7	-1.8	-2.1	-1.9	-1.6	-1.9	-2.0	-2.1	-1.9
Heart disease (mother)	2.1	2.6	3.7	-1.2	-0.6	-1.5	-1.8	-1.6	-1.4	-1.9	-1.4	-1.8	-1.8	-1.7	-1.7	-1.9	-1.7	-1.7	-1.5
Number of self-reported non-cancer illnesses	2.1	3.7	7.9	-2.8	-1.2	-1.5	-2.4	-1.8	-0.8	-2.5	-1.2	-0.9	-1.5	-2.2	-2.2	-2.6	-2.4	-2.0	-1.4
High cholesterol (Self-reported)	2.1	3.8	8.5	-2.9	-0.2	-1.4	-2.3	-1.8	-0.6	-2.4	-1.9	-1.1	-1.9	-2.0	-2.1	-2.4	-2.3	-2.2	-1.3
Type 2 Diabetes (T2D) (2012)	2.0	2.3	7.7	1.3	0.0	1.6	1.2	1.7	1.3	1.5	1.1	2.8	1.9	1.8	0.6	1.6	1.5	1.7	0.0
Hearing difficulty/problems: Yes	2.0	3.1	7.5	-2.7	-0.6	-2.1	-1.7	-1.4	-1.7	-1.9	0.4	-1.0	-1.6	-2.0	-2.3	-1.8	-2.0	-1.9	-1.4
Ever used hormone-replacement therapy (HRT)	2.0	2.6	5.2	-2.3	0.1	-1.5	-1.6	-1.5	-1.3	-1.9	-0.7	-1.4	-1.8	-1.8	-1.8	-1.8	-1.8	-1.8	-1.4
Mouth/teeth dental problems	2.0	3.1	6.2	2.5	2.1	1.5	1.5	1.2	1.2	2.1	-1.5	1.0	1.1	2.1	2.5	2.1	1.9	1.6	0.9
Medication: Cholesterol lowering	2.0	3.1	6.5	-2.5	-0.5	-0.9	-2.2	-1.8	-1.0	-2.0	-2.4	-1.2	-1.9	-1.7	-1.6	-2.0	-2.0	-1.9	-1.5
Pulse wave Arterial Stiffness index	2.0	2.4	5.5	-1.4	-0.2	-1.2	-2.0	-1.7	-0.7	-1.7	-2.3	-1.1	-1.8	-1.5	-1.1	-1.7	-1.8	-1.8	-1.4
Chest pain or discomfort	2.0	2.8	7.8	-2.8	-1.0	-1.4	-1.5	-1.6	-2.1	-1.8	0.5	-1.8	-1.0	-1.9	-1.8	-1.9	-1.6	-1.2	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.1	6.4	2.4	0.9	2.5	2.0	2.1	1.9	2.3	1.0	1.3	2.0	2.2	2.2	2.3	2.2	2.1	2.2
Irritability	2.0	3.4	4.9	-1.5	-1.1	-0.9	-2.2	-2.1	-1.9	-2.0	-2.1	-1.4	-2.0	-2.0	-1.7	-2.0	-2.0	-2.1	-2.0
Vascular/heart problems diagnosed by doctor	2.0	5.4	10.1	3.2	0.9	2.0	2.4	2.3	2.4	2.5	0.8	1.9	2.3	2.7	2.8	2.5	2.6	2.6	2.1
Number of treatments/medications taken	1.9	3.4	8.1	-2.8	-0.3	-1.0	-2.4	-1.5	-0.2	-2.5	-1.8	-0.5	-1.7	-1.9	-2.2	-2.5	-2.3	-2.1	-0.8
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	7.9	-2.8	-0.7	-1.5	-1.3	-1.4	-1.5	-1.5	0.5	-1.2	-1.3	-1.6	-1.7	-1.5	-1.6	-1.5	-1.2
Serious illness, injury or assault to yourself	1.9	2.3	6.5	-1.7	-2.0	-1.0	-1.2	-1.6	-2.5	-1.0	-0.9	-2.4	-1.1	-1.4	-0.7	-1.2	-1.0	-0.9	-2.0
High blood pressure	1.9	5.2	8.2	-2.8	-0.6	-2.5	-2.3	-2.1	-2.2	-2.5	-0.5	-1.9	-2.2	-2.7	-2.9	-2.5	-2.6	-2.5	-2.0
Pulse rate	1.9	3.2	5.2	-1.7	-0.9	-2.3	-2.0	-1.7	-1.2	-2.2	-0.9	-1.1	-1.9	-2.0	-2.1	-2.1	-2.1	-2.0	-1.4
Age at first live birth	1.9	3.4	7.7	2.4	1.4	1.9	1.8	1.2	0.4	2.5	-1.1	1.0	1.4	2.3	2.8	2.4	2.3	2.0	0.7
Financial difficulties in last 2 years	1.8	2.4	7.5	-1.6	-2.7	-1.7	-1.2	-1.3	-1.6	-1.4	0.7	-1.6	-1.1	-1.7	-1.6	-1.4	-1.5	-1.4	-1.4
Cardiovascular Disease	1.7	5.7	8.7	-2.9	-0.9	-2.3	-2.5	-2.3	-2.1	-2.8	-1.3	-2.0	-2.5	-2.7	-2.9	-2.7	-2.8	-2.7	-1.9
Hypothyroidism (self reported)	1.7	3.9	5.8	-1.5	-0.9	-1.8	-2.3	-2.0	-1.5	-2.2	-1.8	-1.6	-2.3	-2.1	-2.1	-2.2	-2.3	-2.4	-1.7
Average weekly spirits intake	1.7	2.1	4.6	0.7	1.9	1.1	1.7	1.7	1.2	1.2	2.1	1.5	1.6	1.3	0.7	1.3	1.4	1.5	1.5
Systolic blood pressure, automated reading	1.7	4.9	10.4	-3.2	-0.6	-2.7	-2.6	-2.0	-0.7	-2.7	-1.2	-0.7	-2.2	-2.4	-2.6	-2.6	-2.7	-2.6	-1.3
Impedance of arm (right)	1.7	7.7	11.5	-2.7	-1.4	-2.4	-3.2	-3.0	-1.8	-3.3	-2.6	-2.5	-3.0	-2.9	-2.9	-3.4	-3.0	-2.9	-2.5
Happiness	1.7	2.0	2.9	-0.9	-1.3	-1.2	-1.6	-1.4	-1.2	-1.6	-0.9	-1.2	-1.4	-1.6	-1.6	-1.7	-1.7	-1.6	-1.4
Commuting to job workplace: Car/motor vehicle	1.7	2.0	5.3	-1.0	-2.3	-1.2	-1.4	-1.4	-1.1	-1.5	-0.4	-1.3	-1.4	-1.5	-1.4	-1.5	-1.5	-1.5	-1.4
Verbal and Numeric Reasoning (VNR)	1.6	3.9	9.4	3.1	1.6	1.7	2.2	1.9	1.3	2.3	1.4	1.3	2.0	2.1	2.0	2.2	2.3	2.2	1.3
Mouth/teeth dental problems: Dentures	1.6	2.7	6.4	-2.5	-1.7	-1.2	-1.6	-1.0	-0.1	-2.3	1.0	-0.1	-1.2	-1.8	-2.5	-2.1	-2.0	-1.7	-0.2
Standing height	1.6	15.6	29.6	5.4	2.2	4.9	4.0	3.3	2.6	5.0	0.0	2.2	3.6	4.5	5.1	4.8	4.6	4.2	2.7
Worry too long after embarrassment	1.6	2.6	5.5	0.1	-1.6	-1.6	-1.5	-1.8	-2.0	-1.3	-0.9	-2.4	-2.0	-1.7	-1.3	-1.3	-1.5	-1.8	-2.0
Wheeze or whistling in the chest in last year	1.6	2.9	10.6	-3.2	-1.1	-1.5	-1.6	-1.5	-0.4	-2.2	0.3	-0.8	-1.0	-2.0	-2.0	-2.2	-2.0	-1.5	-1.1
Hypertension (Self-reported)	1.6	4.4	7.0	-2.6	-0.3	-2.3	-2.1	-2.0	-2.1	-2.3	-0.3	-1.9	-2.1	-2.5	-2.6	-2.3	-2.4	-2.3	-1.9
Medication: Gliclazide	1.6	1.8	2.6	-1.4	-1.3	-1.5	-1.5	-1.4	-1.3	-1.5	-0.6	-1.6	-1.2	-1.5	-1.0	-1.6	-1.4	-1.3	-1.2
Number of operations (self-reported)	1.6	2.4	9.6	-3.1	-0.6	-1.1	-1.2	-1.3	-1.1	-1.8	0.9	-1.2	-1.0	-1.8	-2.0	-1.8	-1.6	-1.3	-1.1
Gout (self-reported)	1.5	2.1	3.0	-1.0	-1.0	-1.4	-1.6	-1.5	-1.5	-1.5	-1.7	-1.5	-1.6	-1.4	-1.2	-1.6	-1.3	-1.4	-1.6
Comparative height size at age 10	1.5	8.5	18.7	4.3	1.0	3.7	3.0	2.3	1.8	3.7	0.6	2.0	2.8	3.2	3.5	3.5	3.3	3.1	1.8
Had major operations	1.5	1.8	3.6	-1.8	-1.5	-1.0	-1.2	-1.0	-0.8	-1.6	1.2	-1.0	-0.7	-1.6	-1.9	-1.7	-1.5	-1.1	-0.8
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	5.9	2.4	0.9	1.5	1.0	1.2	1.9	1.1	-0.9	1.5	0.7	1.5	1.3	1.3	1.1	0.8	1.5
Leg fat-free mass (right)	1.5	7.8	12.5	3.3	1.0	3.2	2.9	2.7	2.1	3.5	1.1	2.0	2.9	3.1	3.5	3.4	3.1	3.0	2.4
Friendships satisfaction	1.5	1.9	4.4	-1.2	-2.1	-1.3	-1.0	-1.1	-1.8	-1.2	0.6	-1.8	-1.2	-1.5	-1.5	-1.2	-1.2	-1.3	-1.4
Breast cancer (self-reported)	1.5	1.8	3.6	-1.2	-0.7	-1.1	-1.5	-1.5	-1.3	-1.2	-1.9	-1.4	-1.6	-1.2	-1.0	-1.2	-1.3	-1.4	-1.4
Leg predicted mass (right)	1.5	7.8	12.5	3.3	1.0	3.2	2.9	2.7	2.1	3.5	1.1	2.0	2.9	3.1	3.5	3.4	3.1	3.0	2.4
Pain experienced in last month	1.5	2.6	4.4	2.1	1.5	0.7	2.0	1.7	0.5	2.1	0.9	0.6	1.4	1.8	1.8	2.1	2.1	1.8	1.1
Neuroticism (Nagel 2018)	1.4	3.3	8.0	-0.6	-1.1	-0.5	-2.1	-2.1	-1.9	-1.7	-2.8	-2.2	-2.1	-1.7	-1.0	-1.8	-1.7	-1.9	-2.1
Number of incorrect matches in round	1.4	2.2	6.1	0.4	2.5	1.8	1.3	1.5	1.9	1.2	0.7	1.7	1.4	1.5	1.4	1.2	1.2	1.3	2.0
Neuroticism score	1.4	2.9	4.4	-0.3	-1.8	-0.8	-1.9	-1.9	-2.0	-1.7	-1.6	-2.1	-1.9	-1.8	-1.3	-1.8	-1.8	-1.8	-1.9
Time employed in main current job	1.4	1.6	3.5	-1.9	0.0	-1.1	-1.4	-1.0	-0.4	-1.8	-0.5	-0.6	-1.2	-1.4	-1.6	-1.7	-1.6	-1.4	-0.5
Average weekly champagne plus white wine intake	1.4	1.9	5.3	1.2	2.3	0.8	1.5	0.9	0.1	1.8	0.7	0.4	1.3	1.4	2.0	1.7	1.7	1.6	0.3
Risk taking	1.4	2.0	3.3	0.2	0.6	1.6	1.7	1.4	0.4	1.6	1.8	0.9	1.8	1.4	1.5	1.6	1.7	1.8	1.1
Leg fat-free mass (left)	1.3	7.1	11.0	3.1	0.7	3.1	2.7	2.6	2.0	3.3	1.1	1.9	2.8	2.9	3.3	3.2	2.9	2.8	2.3
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.1	6.4	-2.3	-0.5	-2.5	-1.7	-1.6	-1.1	-2.0	0.4	-0.7	-1.5	-2.0	-2.4	-1.9	-2.1	-2.0	-1.3
Leg predicted mass (left)	1.3	6.8	10.7	3.1	0.6	3.1	2.7	2.5	2.0	3.3	1.1	1.9	2.7	2.9	3.2	3.2	2.9	2.8	2.2
Had other major operations	1.3	1.6	2.4	0.8	0.5	1.4	1.3	1.3	1.4	1.1	0.7	1.6	1.5	1.3	1.3	1.1	1.3	1.4	1.4
Birth weight of first child	1.3	2.4	4.7	0.7	1.5	2.2	1.2	1.4	1.7	1.6	-0.1	1.7	1.7	1.7	1.9	1.5	1.5	1.6	1.4
Hypothyroidism/myxoedema (self-reported)	1.3	2.4	3.9	-1.1	-0.1	-1.2	-1.8	-1.6	-1.4	-1.8	-1.3	-1.2	-1.9	-1.7	-1.8	-1.7	-1.9	-2.0	-1.5
Medication: Ventolin 100micrograms inhaler	1.3	1.7	3.8	-1.4	0.2	-0.9	-1.7	-1.5	-0.4	-1.5	-1.9	-0.8	-1.2	-1.3	-0.9	-1.7	-1.5	-1.3	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	3.2	-1.8	0.1	-1.5	-1.2	-1.0	-0.7	-1.6	0.5	-0.3	-0.9	-1.5	-1.8	-1.5	-1.5	-1.3	-0.9
Illnesses of father: None of the above (group 1)	1.3	1.6	2.9	0.4	0.8	1.1	1.4	1.4	1.1	1.3	1.4	1.0	1.7	1.3	1.3	1.2	1.4	1.6	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	2.7	-0.2	-1.4	-0.6	-1.4	-1.4	-0.9	-1.4	-1.1	-0.8	-1.5	-1.4	-1.3	-1.3	-1.6	-1.6	-1.4
Qualifications: A levels/AS levels or equivalent	1.2	2.7	4.4	1.9	1.9	0.9	2.0	1.6	0.7	2.0	0.2	1.0	1.5	1.9	1.9	2.0	2.1	1.9	1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.8	1.6	0.2	1.1	1.5	1.3	0.6	1.6	1.2	0.9	0.9	1.3	0.8	1.7	1.4	1.1	0.9
Medication for pain relief, constipation, heartburn	1.2	2.1	4.0	2.0	1.2	0.2	1.8	1.2	0.7	1.8	1.5	0.7	1.7	1.4	1.5	1.7	1.7	1.7	0.7
Neck or shoulder pain in last month	1.2	1.7	3.8	-2.0	-1.7	-1.3	-1.1	-1.1	-0.9	-1.5	0.0	-0.8	-1.1	-1.4	-1.7	-1.4	-1.3	-1.2	-1.0
Average weekly red wine intake	1.2	1.8	3.4	0.9	1.7	1.9	1.4	1.3	1.0	1.4	0.1	0.9	1.2	1.5	1.4	1.4	1.6	1.5	1.2
Ever had bowel cancer screening	1.2	1.4	2.2	0.4	1.3	0.7	1.4	1.5	0.6	1.2	1.4	0.8	1.2	1.2	1.1	1.3	1.4	1.3	1.2
Alzheimer’s Disease (in mother)	1.1	1.3	13.8	-1.1	-0.6	-1.4	0.9	0.7	0.4	0.3	3.7	0.9	0.7	-0.0	-0.6	0.5	0.1	0.2	0.5
Taking other prescription medications	1.1	1.8	5.3	-2.3	0.0	-0.6	-1.8	-1.2	0.0	-1.7	-1.8	-0.1	-1.0	-1.2	-1.2	-1.8	-1.6	-1.3	-0.6
Fluid intelligence score	1.1	2.4	5.6	2.4	0.4	1.0	1.8	1.5	1.2	1.7	1.5	1.3	1.7	1.6	1.3	1.7	1.7	1.8	1.1
Falls in the last year	1.1	1.4	3.1	-1.8	-1.1	-1.6	-1.0	-1.1	-1.2	-1.1	0.4	-1.1	-1.0	-1.4	-1.3	-1.1	-1.2	-1.2	-1.1
Peak expiratory flow (PEF)	1.1	2.6	5.9	0.2	-1.1	-0.9	-2.0	-1.8	-0.7	-1.8	-2.4	-1.4	-2.0	-1.6	-1.4	-1.7	-1.9	-2.0	-1.2
Shortness of breath walking on level ground	1.1	1.3	1.9	-1.3	-1.4	-1.3	-1.2	-1.2	-1.3	-1.1	-0.5	-1.3	-1.0	-1.2	-0.8	-1.2	-1.1	-1.0	-1.2
Long-standing illness, disability or infirmity	1.1	1.6	3.9	-2.0	-0.9	-0.8	-1.4	-1.5	-0.7	-1.2	-1.7	-1.1	-1.2	-1.2	-0.8	-1.3	-1.3	-1.3	-1.2
Mineral and other dietary supplements	1.1	1.5	2.4	0.6	0.6	0.9	1.3	1.4	1.5	1.3	1.0	1.2	1.4	1.4	1.2	1.3	1.3	1.3	1.5
Guilty feelings	1.1	1.6	2.9	-0.3	-1.4	-1.2	-1.3	-1.3	-1.0	-1.3	0.9	-1.1	-1.0	-1.6	-1.7	-1.4	-1.6	-1.4	-1.0
Medication: Paracetamol	1.1	1.7	4.2	-1.3	-2.0	-0.7	-1.3	-1.1	-1.2	-1.3	-1.0	-1.1	-1.6	-1.3	-1.0	-1.2	-1.4	-1.5	-1.1
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	2.4	-1.6	-0.3	-0.7	-1.4	-1.3	-1.1	-1.3	-0.5	-1.0	-0.9	-1.4	-1.2	-1.4	-1.3	-1.1	-1.1
Intelligence (Savage-Jansen 2018)	1.0	3.2	7.0	2.6	1.4	1.6	1.9	1.6	1.0	2.1	0.8	1.2	1.9	1.9	2.0	2.0	2.1	2.0	1.3
Ulcerative Colitis (UC)	1.0	1.8	4.4	1.2	1.9	1.4	1.2	1.0	0.6	1.7	-1.2	0.4	0.9	1.6	2.1	1.6	1.6	1.4	0.6
Ulcerative Colitis	1.0	1.5	3.1	1.1	1.1	1.1	1.4	1.1	0.2	1.8	0.5	0.3	1.1	1.4	1.7	1.7	1.6	1.4	0.0
Height	1.0	18.4	33.7	5.8	1.9	5.7	4.2	3.7	2.3	5.4	0.3	2.3	3.9	4.9	5.5	5.2	5.0	4.7	3.1
Lung FEV1/FVC ratio	1.0	5.0	9.9	-3.1	-0.7	-2.3	-2.2	-2.1	-2.7	-2.2	-0.8	-1.9	-2.5	-2.5	-2.3	-2.0	-2.4	-2.5	-2.5
Neuroticism	1.0	2.5	5.9	-0.4	-1.4	-0.2	-1.7	-1.7	-2.0	-1.3	-2.4	-2.1	-1.9	-1.4	-0.9	-1.4	-1.4	-1.6	-1.8
Heart attack	1.0	1.2	3.9	-2.0	-1.6	-0.4	-1.1	-0.9	-0.8	-1.3	0.0	-0.6	-0.7	-1.3	-1.2	-1.3	-1.2	-1.0	-0.7
Medication: Simvastatin	1.0	1.5	4.6	-2.1	0.1	-1.2	-1.3	-1.1	-0.8	-1.5	-1.0	-0.5	-1.2	-1.3	-1.2	-1.4	-1.4	-1.4	-0.9
Weight	1.0	4.7	7.5	1.8	0.0	2.7	2.3	2.3	1.6	2.7	1.2	1.6	2.4	2.4	2.7	2.6	2.4	2.4	2.0
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	7.0	-0.7	-1.2	-0.0	-1.5	-1.3	-1.0	-1.1	-2.6	-1.2	-1.4	-1.0	-0.5	-1.2	-1.1	-1.3	-1.1
Medication: Blood pressure	1.0	1.7	4.0	-1.7	-0.7	-1.7	-1.3	-0.9	-0.7	-1.6	0.3	-0.3	-1.0	-1.6	-2.0	-1.5	-1.7	-1.5	-0.6
Medication: Omeprazole	1.0	1.2	1.9	-1.4	-0.8	-1.0	-1.2	-1.1	-1.2	-1.1	0.2	-0.8	-0.9	-1.3	-1.2	-1.1	-1.2	-1.1	-1.1
Age at last live birth	1.0	1.5	3.8	1.9	1.0	0.7	1.2	0.7	-0.3	1.8	-0.2	0.3	1.0	1.3	1.9	1.7	1.5	1.3	0.0
Heart attack/myocardial infarction (self-reported)	1.0	1.3	4.2	-2.1	-1.8	-0.4	-1.1	-0.9	-0.8	-1.3	0.1	-0.6	-0.7	-1.3	-1.3	-1.3	-1.3	-1.0	-0.7
Impedance of whole body	1.0	5.1	8.2	-2.8	-1.2	-1.9	-2.4	-2.4	-1.4	-2.8	-1.7	-2.2	-2.3	-2.4	-2.5	-2.9	-2.4	-2.2	-2.0
Depression (Nagel 2018)	0.9	1.3	2.5	-0.3	-1.6	-0.6	-1.2	-1.3	-0.5	-1.3	-0.7	-0.7	-1.4	-1.3	-1.1	-1.3	-1.5	-1.5	-1.1
Heel T-Score	0.9	7.0	17.1	-3.7	-1.9	-4.1	-2.3	-2.0	-1.2	-2.9	1.2	-1.0	-2.2	-2.9	-3.9	-2.7	-3.1	-2.9	-1.4
Respiratory disease	0.9	2.1	6.5	-2.6	-1.4	-1.6	-1.2	-1.4	-0.9	-1.6	0.2	-1.2	-1.0	-1.6	-1.6	-1.7	-1.5	-1.2	-1.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	5.2	-2.3	0.1	-0.8	-1.0	-1.1	-0.7	-1.3	-1.1	-0.7	-0.8	-1.0	-0.9	-1.3	-1.0	-0.8	-0.9
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	1.9	1.0	-1.0	1.4	0.8	1.1	0.8	0.8	0.7	0.9	1.2	0.8	1.0	0.7	0.9	1.0	1.1
Alcohol usually taken with meals	0.9	1.4	4.9	2.2	1.2	0.2	1.2	0.6	-1.0	1.6	-0.6	-0.8	0.4	1.1	1.7	1.5	1.5	1.1	-0.4
Illnesses of mother	0.9	1.1	2.3	1.0	1.0	1.5	1.0	0.9	0.6	1.3	-0.6	0.1	0.9	1.2	1.5	1.2	1.3	1.2	0.8
Exposure to tobacco smoke outside home	0.9	1.1	2.5	-1.3	-1.6	-1.3	-1.0	-0.6	-0.1	-1.2	1.0	-0.1	-0.8	-1.2	-1.5	-1.0	-1.4	-1.3	0.0
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.0	-1.1	-1.4	-0.6	-1.0	-1.0	-0.9	-1.3	0.5	-1.1	-0.5	-1.2	-1.2	-1.4	-1.1	-0.7	-0.6
Mean time to correctly identify matches	0.9	1.7	5.4	-2.3	-0.7	-0.9	-1.5	-1.2	-0.4	-1.7	-0.1	-0.1	-0.7	-1.5	-1.5	-1.8	-1.6	-1.2	-0.9
Alzheimer’s Disease (including proxy)	0.8	1.2	8.1	-1.5	-1.1	-1.8	0.1	-0.3	-0.4	-0.4	2.9	-0.3	-0.0	-0.9	-1.1	-0.4	-0.6	-0.5	-0.6
Medication: Metformin	0.8	1.2	2.2	-0.5	-1.5	-1.1	-1.2	-0.8	-1.1	-1.3	0.2	-0.6	-0.7	-1.3	-1.2	-1.4	-1.3	-1.1	-0.8
Stomach or abdominal pain in last month	0.8	1.1	3.8	-1.9	-0.2	-1.2	-1.1	-0.9	-0.4	-1.2	-0.4	-0.6	-0.8	-1.1	-1.1	-1.2	-1.2	-1.0	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	4.6	-1.5	-0.8	-2.1	-1.3	-1.2	-0.9	-1.5	0.2	-0.9	-1.2	-1.5	-1.7	-1.4	-1.6	-1.5	-1.1
Allergy	0.8	1.8	4.1	2.0	1.6	0.7	1.4	1.2	0.9	1.6	0.4	1.4	1.1	1.5	1.3	1.6	1.4	1.2	1.1
Medication: Lansoprazole	0.8	0.9	2.7	-0.6	-0.1	-1.0	-1.2	-1.1	0.1	-1.1	-1.6	-0.2	-1.0	-0.8	-0.7	-1.1	-1.1	-1.1	-0.9
Blood clot in the leg (DVT)	0.8	1.0	3.9	0.0	-0.7	-0.8	-1.2	-1.1	-1.1	-0.9	-2.0	-0.8	-1.1	-0.8	-0.5	-0.9	-0.9	-1.0	-1.2
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	3.2	1.8	0.4	0.9	1.4	1.0	0.4	1.4	0.9	0.4	1.1	1.2	1.5	1.4	1.5	1.4	0.6
Alcohol intake frequency.	0.8	1.8	2.8	-0.5	-1.6	-1.0	-1.6	-1.5	-1.0	-1.6	-1.4	-1.1	-1.4	-1.4	-1.2	-1.7	-1.5	-1.4	-1.2
Hearing aid user	0.8	0.9	2.0	-1.2	-0.4	-0.8	-0.8	-1.0	-1.4	-0.7	0.7	-0.8	-0.8	-1.1	-1.1	-0.8	-1.0	-0.9	-1.2
Fractured/broken bones in last 5 years	0.8	1.0	2.0	0.9	1.3	0.8	1.1	1.0	0.3	1.1	-0.6	0.4	0.7	1.2	1.4	1.1	1.3	1.1	0.6
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	4.0	0.1	-0.8	-0.7	-1.2	-1.1	-1.2	-0.7	-2.0	-1.0	-1.2	-0.8	-0.4	-0.8	-0.8	-1.0	-1.2
Worry (Nagel 2018)	0.7	1.4	4.2	-0.1	0.3	0.2	-1.4	-1.3	-1.4	-1.0	-2.0	-1.5	-1.5	-1.1	-0.6	-1.0	-1.1	-1.3	-1.2
Irritable Bowel Disease (IBD)	0.7	1.7	4.3	0.9	1.4	1.4	1.4	0.9	0.5	1.7	-0.8	0.2	1.1	1.5	2.1	1.6	1.7	1.5	0.4
Neuroticism (2016)	0.7	1.0	1.8	-0.2	-1.3	-0.5	-1.2	-1.1	-0.2	-1.2	-1.1	-0.9	-1.1	-1.1	-0.9	-1.2	-1.1	-1.1	0.0
Hand grip strength (left)	0.7	1.8	6.4	2.5	1.3	1.9	1.2	1.0	0.9	1.4	-0.4	0.6	0.9	1.4	1.6	1.5	1.3	1.1	1.0
Frequency of depressed mood in last 2 weeks	0.7	0.9	2.1	-0.1	-1.5	-0.0	-1.1	-1.1	-0.6	-0.9	-1.4	-0.7	-1.1	-0.9	-0.6	-0.9	-1.0	-1.0	-1.2
Medication for hormone replacement therapy	0.7	0.7	3.0	-1.7	0.5	-1.1	-0.3	-0.5	-1.0	-0.7	1.1	-0.7	-0.4	-0.9	-1.0	-0.7	-0.7	-0.6	-0.7
Breastfed as a baby	0.7	0.9	3.5	-0.4	0.9	-0.7	-1.2	-0.9	-0.4	-0.9	-1.9	-0.3	-1.1	-0.7	-0.4	-0.9	-1.0	-1.1	-0.7
Qualifications: nursing, teaching	0.7	1.1	2.0	0.7	0.2	0.5	1.4	1.1	0.4	1.2	1.3	0.8	1.3	1.1	1.2	1.1	1.3	1.4	0.7
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	2.5	-0.2	1.6	1.0	1.1	1.3	0.9	0.9	1.2	1.0	1.4	1.0	1.0	0.8	1.1	1.3	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.9	3.3	-0.5	-1.8	-0.9	-0.7	-0.9	-0.9	-0.8	-0.2	-0.7	-0.8	-0.9	-0.8	-0.8	-0.8	-0.9	-1.4
Cholesterol lowering medication	0.7	1.0	1.9	-1.2	0.2	-0.7	-1.2	-0.9	-0.4	-1.4	-0.4	-0.1	-1.0	-1.2	-1.2	-1.3	-1.4	-1.3	-0.6
Depressed Affect (Nagel 2018)	0.6	1.3	5.0	-0.0	-1.4	0.2	-1.3	-1.3	-0.8	-1.0	-2.2	-1.2	-1.2	-0.9	-0.3	-1.1	-0.9	-1.0	-1.2
Lung FVC	0.6	3.2	6.1	-0.8	-2.5	-1.5	-1.8	-1.8	-2.0	-1.6	-0.9	-1.4	-2.2	-1.9	-2.0	-1.4	-2.0	-2.2	-1.7
Hair/balding pattern: Pattern 3	0.6	1.0	3.0	0.5	1.7	0.6	1.0	1.0	0.1	0.8	1.6	0.6	1.2	0.7	0.7	0.8	1.0	1.1	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.4	0.8	0.8	0.7	0.6	0.8	1.5	0.8	-1.1	0.9	0.4	1.0	1.1	0.8	0.7	0.6	1.1
Hair/balding pattern: Pattern 4	0.6	1.4	3.4	1.8	0.0	1.4	1.3	1.1	0.1	1.6	-0.2	-0.0	1.0	1.4	1.4	1.5	1.6	1.4	0.8
Headache pain in last month	0.6	1.0	1.8	-1.1	-0.9	-0.7	-1.3	-0.8	-0.6	-1.2	-0.8	-0.2	-1.1	-1.1	-1.0	-1.1	-1.4	-1.3	-0.4
Emphysema/chronic bronchitis	0.6	0.6	5.1	-0.8	-2.3	-0.2	-0.5	-0.6	-0.7	-0.6	0.2	-0.6	-0.5	-0.7	-0.5	-0.6	-0.6	-0.6	-0.7
Medication: Seretide 50 evohaler	0.6	0.7	1.8	0.5	0.9	0.5	1.0	0.8	0.5	0.8	1.3	0.0	1.0	0.6	0.7	0.7	0.9	1.0	0.7
Suffer from ‘nerves’	0.6	0.9	2.2	-0.3	-0.3	-0.4	-0.8	-1.2	-1.5	-0.8	-0.1	-1.2	-1.2	-1.1	-0.7	-0.7	-1.0	-1.2	-1.1
Supplements: Vitamin C	0.6	0.7	1.6	0.6	0.4	1.3	0.7	0.9	0.4	0.7	0.5	1.0	0.9	0.8	0.7	0.7	0.8	0.8	1.1
Knee pain experienced in last month	0.6	1.0	2.4	-1.5	-0.7	0.0	-1.1	-0.9	-0.3	-1.5	-0.6	-0.4	-0.8	-1.2	-1.1	-1.5	-1.3	-1.0	-0.4
Illnesses of father: Heart disease	0.6	0.9	1.6	-0.4	-1.1	-0.9	-1.0	-1.0	-0.3	-1.1	-1.2	-0.7	-1.3	-0.8	-1.0	-1.0	-1.0	-1.1	-0.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.1	0.4	0.4	0.8	0.7	1.1	1.0	0.8	0.7	1.5	0.8	0.8	0.3	0.8	0.6	0.6	1.1
Medication for cholesterol	0.6	0.9	2.1	1.5	-0.4	0.9	0.6	0.5	1.1	1.0	-1.1	0.7	0.8	1.1	1.4	0.9	1.0	1.0	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	2.0	-0.7	-0.8	-0.9	-1.4	-1.3	-0.9	-1.4	-0.6	-0.8	-1.3	-1.3	-1.3	-1.4	-1.4	-1.4	-1.0
Alcohol drinker status: Never	0.6	0.7	1.9	0.2	1.4	-0.8	-0.9	-0.8	-0.7	-0.8	-1.2	-0.4	-1.0	-0.7	-0.5	-0.7	-0.8	-0.9	-0.8
Age started oral contraceptive pill	0.6	0.8	4.8	2.2	0.2	0.7	-0.0	-0.4	-1.5	0.6	-0.8	-0.6	-0.0	0.2	1.2	0.4	0.6	0.4	-1.2
Diastolic blood pressure, automated reading	0.6	1.9	6.1	-2.5	-0.7	-1.9	-1.5	-0.9	0.3	-1.6	-0.8	0.1	-1.3	-1.3	-1.7	-1.5	-1.7	-1.6	-0.2
Alcohol drinker status: Previous	0.6	0.7	3.6	-0.9	-1.9	-0.8	-0.3	-0.5	-0.9	-0.7	-0.1	-1.0	-0.8	-0.6	-0.9	-0.6	-0.5	-0.6	-0.5
Waist circumference	0.5	1.7	2.5	-0.4	0.2	1.4	1.4	1.6	1.1	1.4	1.3	1.4	1.5	1.3	1.3	1.4	1.3	1.3	1.5
Alcohol intake versus 10 years previously	0.5	0.8	3.1	-1.8	-0.3	-0.4	-1.1	-0.7	-0.2	-1.3	-1.0	-0.1	-0.6	-0.8	-1.0	-1.3	-0.9	-0.7	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.5	0.0	0.1	-0.6	-1.0	-0.9	-0.5	-0.9	-0.9	-0.4	-1.2	-0.9	-0.9	-0.8	-1.1	-1.2	-0.8
Loud music exposure frequency	0.5	0.5	2.0	-0.5	-0.2	-0.1	-0.9	-0.7	0.0	-0.9	-1.4	-0.8	-0.9	-0.6	-0.5	-0.9	-0.8	-0.9	-0.3
Medication: Paracetamol	0.5	0.8	3.9	-0.4	-2.0	0.0	-0.9	-0.7	-0.7	-0.8	-1.4	-0.9	-1.2	-0.6	-0.3	-0.7	-0.7	-1.0	-0.6
Forced vital capacity (FVC), Best measure	0.5	1.7	5.5	2.3	0.1	2.0	1.1	1.0	1.1	1.5	-0.0	0.7	1.0	1.3	1.5	1.5	1.2	1.1	1.1
Commuting to job workplace: Walk	0.5	0.6	4.9	-2.2	1.1	-0.3	-0.4	0.1	0.3	-0.6	0.6	0.7	0.4	-0.4	-0.8	-0.7	-0.5	-0.0	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.7	-0.6	-1.6	-0.3	-0.4	-0.3	0.2	-0.9	1.1	0.1	-0.2	-0.8	-1.3	-0.8	-0.8	-0.6	0.2
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.5	1.0	1.9	0.0	0.7	0.5	-0.1	0.9	-0.2	0.3	0.4	0.7	0.8	0.9	0.8	0.6	0.2
Pack years of smoking	0.5	0.7	1.3	-0.6	-1.2	-0.6	-0.8	-0.8	-1.0	-1.0	-0.2	-0.5	-0.8	-1.0	-1.0	-1.0	-1.0	-0.9	-0.9
Bipolar Disorder (2018)	0.4	0.6	1.8	0.4	-0.0	0.6	1.1	0.9	0.0	1.1	1.4	0.5	0.7	0.7	0.5	1.1	0.9	0.7	0.0
Bipolar Disorder or Schizophrenia	0.4	1.0	1.9	0.3	-0.1	1.0	1.4	1.0	0.6	1.3	1.2	0.9	1.2	1.1	0.9	1.3	1.2	1.2	0.0
Body Mass Index (BMI) (2010)	0.4	0.6	1.2	1.1	-0.9	0.7	0.8	0.8	0.4	0.8	0.8	0.1	0.7	0.7	0.6	0.7	0.8	0.7	1.0
Coronary Artery Disease (CAD)	0.4	0.4	1.4	-1.0	0.9	-1.1	0.3	-0.2	-1.0	-0.1	0.8	-0.9	-0.2	-0.4	-1.2	0.0	-0.1	-0.2	-0.1
Schizophrenia (2014)	0.4	0.9	1.7	0.1	0.2	0.6	1.3	0.9	0.7	1.1	1.2	0.9	1.2	1.1	0.9	1.2	1.1	1.2	0.0
Blood Platelet Count	0.4	4.7	11.6	-2.6	0.6	-3.4	-2.2	-1.9	-1.1	-2.6	-0.8	-1.2	-2.2	-2.4	-2.4	-2.5	-2.5	-2.5	-1.6
Waist Hip Ratio (WHR)	0.4	1.8	6.2	-2.5	1.0	-1.5	-1.3	-0.8	0.7	-1.5	-0.7	0.3	-1.3	-1.1	-1.5	-1.3	-1.7	-1.7	-0.3
Chronotype (morning person)	0.4	0.9	3.7	0.1	-1.3	-0.0	-1.2	-1.1	-0.1	-0.9	-1.9	-0.7	-1.1	-0.8	-0.4	-1.0	-1.0	-1.0	-0.8
Supplements: Zinc	0.4	0.4	2.0	0.4	1.4	0.5	0.4	0.6	0.8	0.3	0.3	0.9	0.6	0.5	0.4	0.3	0.4	0.5	0.8
Diabetes (father)	0.4	0.4	0.9	1.0	0.5	0.3	0.9	0.7	-0.1	0.8	0.7	0.3	0.7	0.6	0.7	0.8	0.8	0.8	0.2
Trunk fat percentage	0.4	1.5	4.9	-2.2	-1.9	-0.7	-1.3	-0.9	-0.7	-1.3	-0.6	-1.0	-1.0	-1.2	-1.0	-1.3	-1.3	-1.1	-0.8
Hand grip strength (right)	0.4	1.0	4.2	2.0	0.7	1.2	1.0	0.7	0.8	1.0	-0.1	0.2	0.7	1.0	1.2	1.1	0.9	0.8	0.8
Relative age voice broke	0.4	0.7	1.4	0.3	1.1	1.2	0.4	0.7	0.5	0.8	-1.2	0.5	0.3	1.0	1.2	0.8	0.8	0.6	0.8
Age when periods started (menarche)	0.4	1.1	2.9	-0.6	1.0	0.0	1.1	1.2	1.4	0.7	1.7	1.4	1.0	0.9	0.6	0.9	0.8	0.8	1.3
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.3	-1.5	-0.8	0.3	-1.1	-0.9	-0.6	-1.1	-0.6	-1.1	-0.6	-1.0	-0.9	-1.2	-1.0	-0.7	-0.8
Exposure to tobacco smoke at home	0.4	0.4	1.5	-0.3	-0.3	-1.2	-0.8	-0.6	-0.1	-0.6	-0.5	-0.4	-0.9	-0.6	-0.6	-0.6	-0.8	-0.9	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.6	-1.2	-0.5	-0.8	-0.7	-0.7	-0.5	-0.8	0.1	-0.4	-0.6	-0.8	-0.6	-0.8	-0.9	-0.7	-0.5
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.6	0.7	-0.2	0.3	0.9	0.9	0.4	0.6	1.6	0.4	0.8	0.5	0.2	0.6	0.6	0.6	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	2.5	1.6	-1.4	0.6	-0.2	-0.6	-0.3	-0.2	-0.1	-0.8	-0.5	-0.3	0.1	-0.1	-0.2	-0.3	-0.7
Smoking status: Previous	0.4	0.5	3.1	-1.8	-0.3	-0.3	-0.4	-0.3	0.0	-0.9	0.8	0.2	-0.2	-0.8	-1.1	-0.8	-0.8	-0.5	-0.1
Arm fat percentage (left)	0.4	1.4	5.2	-2.3	-1.9	-0.7	-1.3	-0.8	-0.3	-1.4	-0.5	-0.6	-0.9	-1.2	-1.2	-1.4	-1.4	-1.2	-0.5
Osteoporosis (self-reported)	0.4	0.5	1.9	-0.6	-0.6	-0.6	-0.7	-0.8	-0.5	-0.7	-1.4	-0.9	-0.7	-0.6	0.0	-0.7	-0.5	-0.5	-0.6
Medication: Blood pressure	0.4	0.7	1.7	-1.3	0.5	-0.4	-0.7	-0.4	-1.0	-1.0	0.3	-1.0	-0.8	-1.0	-1.2	-0.9	-0.9	-0.9	-0.5
Ever smoked	0.4	0.6	1.3	-1.1	-0.4	-0.4	-0.9	-0.9	-0.4	-1.1	-0.5	0.0	-0.5	-0.9	-0.8	-1.1	-1.0	-0.8	-0.7
Alzheimer’s Disease (in father)	0.3	0.3	1.0	0.8	0.2	0.6	0.7	0.2	-0.0	0.7	0.0	-0.1	0.6	0.6	1.0	0.6	0.8	0.8	-0.3
Crohns Disease (2012)	0.3	0.6	1.1	0.7	1.0	1.0	0.8	0.6	-0.0	0.9	-0.1	0.0	0.6	0.8	0.9	0.9	1.0	0.9	0.0
Triglycerides	0.3	0.5	2.2	1.0	-0.1	0.5	0.8	0.6	0.4	0.6	1.5	0.7	0.5	0.5	0.1	0.8	0.5	0.4	0.8
Blood Red Count	0.3	3.1	4.5	-2.1	-1.9	-2.0	-1.9	-1.6	-1.4	-2.0	-0.4	-0.8	-1.9	-1.9	-2.0	-1.8	-2.1	-2.1	-1.4
Allergy or Eczema	0.3	0.9	1.8	-1.4	-1.2	0.2	-1.0	-0.9	-1.2	-0.9	-0.1	-1.3	-0.4	-1.1	-0.8	-1.1	-0.8	-0.5	-1.0
Vitamin and mineral supplements	0.3	0.4	1.2	-0.0	-0.6	-0.5	-0.5	-0.8	-0.8	-0.4	-0.8	-1.0	-0.9	-0.5	-0.5	-0.4	-0.4	-0.6	-1.1
Townsend deprivation index at recruitment	0.3	0.5	1.6	-1.3	-0.3	-0.4	-0.4	-0.4	-0.2	-0.7	1.2	0.2	-0.0	-0.7	-1.1	-0.7	-0.7	-0.4	-0.1
Average weekly fortified wine intake	0.3	0.3	3.5	0.2	-0.7	-0.4	0.6	0.4	0.0	0.2	1.9	-0.2	0.5	0.0	-0.4	0.2	0.2	0.3	0.3
Medication: Levothyroxine sodium	0.3	0.5	1.6	-0.8	-0.1	-0.3	-0.7	-0.4	-0.3	-1.1	0.3	0.1	-0.6	-0.9	-1.3	-1.0	-1.0	-0.9	-0.3
Past tobacco smoking	0.3	0.6	2.3	1.5	0.6	0.5	0.7	0.5	0.1	1.1	-0.2	-0.1	0.4	0.9	1.1	1.0	1.0	0.8	0.4
Hearing difficulty/problems with background noise	0.3	0.5	0.8	-0.9	0.6	-0.3	-0.8	-0.6	-0.7	-0.8	-0.4	-0.6	-0.8	-0.7	-0.8	-0.7	-0.7	-0.8	-0.5
Forced vital capacity (FVC)	0.3	1.3	6.9	2.6	-0.4	1.9	0.7	0.5	0.7	1.3	-0.9	0.4	0.5	1.1	1.3	1.3	0.9	0.7	0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	0.9	-0.2	-0.4	0.1	-0.8	-0.5	-0.1	-0.9	0.1	-0.4	-0.3	-0.8	-1.0	-0.9	-0.8	-0.5	-0.3
Arm fat percentage (right)	0.3	1.1	4.1	-2.0	-1.6	-0.5	-1.2	-0.7	-0.3	-1.2	-0.6	-0.5	-0.9	-1.1	-1.0	-1.2	-1.2	-1.1	-0.4
Noisy workplace	0.3	0.4	3.9	1.1	-0.5	0.7	-0.4	-0.0	0.3	-0.0	-2.0	-0.2	-0.2	0.3	0.9	-0.1	0.1	0.1	0.1
Depression (self-reported)	0.3	0.4	2.5	1.2	1.0	0.7	-0.1	-0.2	0.2	0.1	-1.6	-0.1	-0.1	0.3	0.6	0.1	0.2	0.1	-0.1
Prospective memory result	0.3	0.4	0.6	0.3	0.4	-0.8	-0.8	-0.8	-0.7	-0.6	-0.2	-0.6	-0.7	-0.7	-0.6	-0.6	-0.7	-0.8	-0.7
Leg fat mass (right)	0.3	1.0	2.0	-0.4	-0.8	1.4	0.9	1.2	0.9	0.9	1.0	1.0	1.1	0.9	1.0	0.9	0.9	0.9	1.2
Family relationship satisfaction	0.3	0.4	1.9	-0.4	-1.4	-0.2	-0.1	-0.3	-0.7	-0.3	1.2	-0.8	-0.3	-0.6	-0.9	-0.3	-0.4	-0.4	-0.3
Mood swings	0.3	0.6	5.0	0.4	0.3	0.8	-0.9	-0.5	0.8	-0.6	-2.2	0.3	-0.5	-0.1	0.4	-0.6	-0.5	-0.5	-0.1
Miserableness	0.3	0.5	0.9	0.3	-0.4	-0.4	-0.8	-0.9	-0.5	-0.6	-0.9	-0.9	-0.7	-0.8	-0.5	-0.7	-0.8	-0.8	-0.9
Ever taken oral contraceptive pill	0.3	0.3	1.1	0.5	-0.8	0.5	0.3	0.4	1.0	0.4	-0.4	-0.1	0.5	0.5	0.7	0.3	0.5	0.6	0.6
Medication: Bendroflumethiazide	0.3	0.5	5.7	-1.1	2.4	0.1	0.1	0.1	-0.1	0.1	-0.3	-0.0	0.1	0.1	0.1	0.1	0.2	0.1	-0.2
Average weekly beer plus cider intake	0.3	0.5	1.4	-0.5	-0.9	-0.1	-0.7	-0.1	1.2	-0.9	-0.3	0.9	-0.2	-0.4	-0.7	-0.8	-0.8	-0.6	0.6
Ever depressed for a whole week	0.3	0.4	1.3	1.1	-0.5	0.6	0.6	0.3	-0.1	1.0	0.1	-0.3	0.3	0.6	1.0	0.9	0.7	0.5	0.0
Myopia	0.3	0.5	1.1	0.8	0.1	0.3	0.7	0.6	0.1	1.1	-0.2	0.2	0.6	0.8	1.0	1.0	0.9	0.8	0.3
Leg fat mass (left)	0.3	1.3	2.5	-0.3	-0.7	1.6	1.1	1.4	1.1	1.1	1.1	1.2	1.3	1.1	1.1	1.1	1.1	1.2	1.4
Schizophrenia (2018)	0.2	0.5	0.9	0.1	-0.1	0.7	0.8	0.6	0.8	0.8	0.4	0.7	0.9	0.9	0.8	0.8	0.9	0.9	0.0
Major Depression (MDD)	0.2	0.3	1.4	0.3	-1.2	0.0	-0.2	-0.5	0.1	-0.4	-0.9	-0.5	-0.5	-0.4	-0.2	-0.4	-0.5	-0.5	0.1
Reaction Time	0.2	0.4	2.1	-1.4	-0.4	0.1	0.0	0.3	1.0	-0.4	1.2	1.0	0.6	-0.2	-0.3	-0.4	-0.3	0.1	0.5
Breast Cancer	0.2	0.4	1.6	0.4	1.3	0.2	0.4	0.8	1.1	0.4	-0.1	1.1	0.4	0.6	-0.1	0.5	0.4	0.3	0.9
Mean Putamen Volume	0.2	0.2	0.5	-0.5	-0.4	-0.3	-0.3	-0.2	-0.0	-0.7	0.6	-0.7	-0.1	-0.6	-0.5	-0.7	-0.4	-0.2	-0.0
HDL Cholesterol	0.2	0.3	1.7	-1.3	-0.2	-0.9	-0.0	-0.1	-0.0	-0.2	1.1	0.6	-0.1	-0.3	-0.6	-0.1	-0.4	-0.4	0.1
LDL Cholesterol	0.2	0.3	0.8	-0.3	0.3	-0.9	-0.3	-0.5	-0.8	-0.5	0.0	-0.9	-0.6	-0.6	-0.5	-0.5	-0.5	-0.5	-0.9
Lupus	0.2	0.3	2.7	0.5	0.3	0.5	-0.6	-0.3	0.5	-0.6	-1.7	-0.1	-0.3	-0.1	0.1	-0.6	-0.3	-0.2	-0.1
Blood White Count	0.2	1.5	7.0	-0.4	0.6	0.1	1.2	1.1	1.4	0.8	2.6	1.3	1.8	0.8	1.1	0.7	1.0	1.4	0.8
BMI	0.2	1.2	3.7	-0.5	-0.8	1.0	1.0	1.3	1.1	0.7	1.9	1.4	1.4	0.7	0.6	0.7	0.7	1.0	1.4
Smoking Status	0.2	0.4	1.1	0.7	-0.8	1.0	0.6	0.6	1.0	0.2	0.5	0.8	0.6	0.4	0.4	0.3	0.4	0.5	0.5
Severe depression (siblings)	0.2	0.2	1.7	-0.0	-1.3	-0.3	-0.0	0.2	0.7	-0.1	0.8	0.8	0.2	-0.0	-0.0	-0.0	-0.2	-0.1	0.3
Pack years adult smoking proportion	0.2	0.3	1.1	-0.3	-1.1	-0.3	-0.5	-0.6	-0.6	-0.7	-0.2	-0.2	-0.5	-0.6	-0.6	-0.6	-0.6	-0.6	-0.6
Current tobacco smoking	0.2	0.4	2.6	1.6	-0.8	0.4	0.5	0.4	0.3	0.4	0.2	0.5	0.4	0.5	0.6	0.5	0.5	0.4	0.3
Multivitamins +/- minerals	0.2	0.3	1.6	0.2	1.3	0.2	0.2	0.5	1.0	0.1	0.4	0.6	0.6	0.2	0.2	0.0	0.1	0.3	0.9
Supplements: Glucosamine	0.2	0.3	2.3	-0.2	1.5	-0.1	-0.6	-0.6	-0.4	-0.2	-0.5	0.1	-0.2	-0.3	-0.3	-0.3	-0.4	-0.3	-0.6
High blood pressure (mother)	0.2	0.2	1.2	0.2	0.8	0.8	-0.3	-0.1	0.6	0.1	-1.1	0.5	0.2	0.2	0.5	-0.0	0.1	0.1	0.0
Diabetes (self-reported)	0.2	0.3	1.2	0.2	-0.1	-0.4	-0.7	-0.5	-0.6	-0.6	-1.1	-0.2	-0.5	-0.4	-0.2	-0.6	-0.5	-0.5	-0.5
Medication: Ramipril	0.2	0.3	3.7	-0.2	-0.1	-0.3	0.1	0.0	-0.6	-0.1	1.9	0.0	0.2	-0.5	-0.5	-0.1	-0.2	-0.1	-0.1
Worrier / anxious feelings	0.2	0.4	1.7	0.1	0.5	0.5	-0.9	-0.7	-0.0	-0.7	-1.3	-0.2	-0.7	-0.5	-0.5	-0.7	-0.8	-0.7	-0.4
Number of live births	0.2	0.3	2.3	-0.8	-0.2	-0.2	0.2	0.2	0.4	-0.1	1.5	0.7	0.2	-0.2	-0.5	0.0	-0.2	-0.1	0.1
Asthma	0.2	0.4	1.8	-1.4	-0.4	-0.7	-0.3	-0.5	-0.0	-0.8	0.8	-0.6	-0.1	-0.7	-0.6	-0.8	-0.6	-0.4	-0.3
Lung cancer (father)	0.2	0.2	1.0	-1.0	-0.6	-0.2	-0.4	-0.4	-0.7	-0.5	0.2	-0.4	-0.2	-0.5	-0.5	-0.5	-0.4	-0.3	-0.4
Pulse wave reflection index	0.2	0.2	0.4	-0.4	-0.1	0.3	-0.6	-0.5	0.1	-0.6	-0.5	0.1	-0.4	-0.5	-0.5	-0.6	-0.6	-0.5	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.9	-0.5	0.9	-0.9	-0.5	-0.4	-0.4	-0.5	-1.0	-0.6	-0.4	-0.3	-0.3	-0.5	-0.2	-0.2	-0.6
Body fat percentage	0.2	0.8	4.6	-2.1	-1.7	-0.2	-0.8	-0.4	-0.3	-0.9	-0.1	-0.4	-0.5	-0.8	-0.7	-0.9	-0.8	-0.7	-0.2
Comparative body size at age 10	0.2	0.6	1.4	0.6	-0.2	0.3	1.1	0.6	-0.2	1.0	1.2	0.7	0.7	0.7	0.6	1.0	0.9	0.8	0.0
Number of full brothers	0.2	0.2	1.6	0.1	-1.3	0.5	0.2	-0.0	0.2	0.3	-0.8	-0.2	-0.1	0.3	0.5	0.3	0.3	0.2	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.9	0.6	0.3	1.0	0.4	0.3	0.6	0.3	-0.4	0.4	0.6	0.5	0.7	0.3	0.5	0.6	0.5
Qualifications: College or University degree	0.2	0.7	3.8	0.8	2.0	-0.2	0.8	0.2	-1.2	1.0	0.2	-0.6	0.6	0.5	0.7	0.8	0.9	0.9	-0.5
Medication: Ibuprofen	0.2	0.3	1.5	-0.1	0.5	0.2	-0.2	0.3	1.2	0.0	-1.1	0.7	-0.0	0.3	0.2	0.1	-0.0	-0.1	0.8
Whole body fat mass	0.2	0.6	1.6	-0.4	-0.8	1.3	0.7	0.9	0.7	0.8	0.4	0.7	0.9	0.8	1.0	0.8	0.7	0.8	0.9
Number of full sisters	0.2	0.2	1.8	0.0	0.1	0.0	0.4	0.6	0.1	0.2	1.3	0.7	0.3	0.2	0.0	0.3	0.2	0.2	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.6	-0.5	0.3	0.5	-0.6	-0.3	0.6	-0.6	-0.8	-0.1	-0.1	-0.3	0.1	-0.7	-0.4	-0.2	0.2
Illnesses of siblings: Diabetes	0.2	0.3	1.1	0.1	0.5	0.1	0.4	0.7	1.1	0.3	0.7	0.4	0.5	0.4	0.4	0.3	0.2	0.3	1.0
Loneliness, isolation	0.2	0.3	2.0	1.4	-0.7	0.8	0.1	0.2	0.4	0.2	0.3	0.1	0.4	0.2	0.4	0.1	0.2	0.3	0.2
Back pain experienced in last month	0.2	0.2	0.8	-0.9	-0.5	-0.2	-0.4	-0.7	-0.3	-0.5	-0.1	0.2	-0.4	-0.5	-0.5	-0.5	-0.5	-0.4	-0.5
Asthma (self-reported)	0.2	0.4	2.0	-1.4	-0.3	-0.7	-0.3	-0.4	0.1	-0.7	0.7	-0.6	-0.1	-0.7	-0.6	-0.8	-0.6	-0.3	-0.2
Smoking status: Current	0.2	0.4	2.2	1.5	-0.6	0.5	0.6	0.4	0.3	0.5	0.1	0.4	0.3	0.5	0.7	0.6	0.6	0.5	0.3
Wears glasses or contact lenses	0.2	0.2	0.8	-0.5	-0.5	-0.5	-0.3	-0.5	-0.9	-0.2	0.1	-0.3	-0.2	-0.5	0.1	-0.2	-0.3	-0.3	-0.8
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	-0.4	-0.8	-0.7	-0.3	-0.4	-0.3	-0.6	0.8	-0.5	-0.4	-0.5	-0.4	-0.6	-0.4	-0.3	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.7	0.0	-0.9	0.6	-0.6	-0.5	0.0	-0.6	-0.4	-0.2	-0.2	-0.6	-0.1	-0.7	-0.6	-0.4	-0.4
Leg fat percentage (left)	0.2	0.6	1.8	-1.4	-1.0	0.9	0.5	0.9	0.7	0.3	1.1	0.8	0.8	0.4	0.4	0.3	0.4	0.6	0.9
Schizophrenia vs Biploar Disorder	0.1	0.1	0.6	0.6	0.1	0.4	0.1	0.1	0.7	0.1	-0.5	0.1	0.3	0.2	0.5	0.0	0.2	0.3	0.0
Crohns Disease (2017)	0.1	0.2	0.4	-0.2	-0.2	0.4	0.5	0.2	-0.1	0.6	-0.4	-0.2	0.3	0.4	0.6	0.5	0.6	0.5	-0.2
Prostate Cancer	0.1	0.1	0.6	-0.1	-0.3	-0.1	0.0	-0.2	-0.7	-0.3	0.3	-0.6	-0.3	-0.3	-0.5	-0.2	-0.2	-0.3	-0.2
Primary Biliary Cirrhosis	0.1	0.2	0.6	0.5	0.8	0.0	0.6	0.6	0.1	0.4	0.5	0.3	0.3	0.4	0.1	0.5	0.5	0.4	0.5
Blood Eosinophil Count	0.1	0.6	4.5	-0.2	-1.6	-0.7	0.3	0.1	-0.2	-0.0	2.1	-0.6	0.7	-0.4	-0.2	-0.2	-0.0	0.3	-0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.1	1.4	1.2	-0.1	-0.1	-0.1	0.3	-0.3	0.2	-0.2	0.2	0.3	0.2	0.6	0.1	0.2	0.3	0.0
Relative age of first facial hair	0.1	0.2	0.9	0.4	0.3	0.5	0.2	0.1	-0.7	0.5	-0.9	-0.3	-0.2	0.4	0.7	0.5	0.4	0.1	-0.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.6	-0.8	0.3	-0.2	-0.0	0.2	-0.1	-0.3	0.6	-0.2	-0.3	-0.3	-0.7	-0.2	-0.3	-0.4	0.3
Impedance of leg (right)	0.1	0.5	1.5	-1.2	-0.3	-0.6	-0.5	-0.5	-0.3	-1.0	0.3	-0.6	-0.6	-0.7	-1.0	-1.0	-0.6	-0.5	-0.4
Body mass index (BMI)	0.1	0.5	1.3	-0.6	-1.0	0.6	0.6	0.9	0.5	0.6	1.1	0.7	0.8	0.5	0.5	0.6	0.5	0.5	0.8
Trunk fat mass	0.1	0.3	1.2	-0.5	-1.1	0.9	0.3	0.5	0.4	0.4	-0.0	0.3	0.4	0.4	0.7	0.4	0.3	0.4	0.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	1.5	0.7	-1.2	0.3	-0.1	-0.2	0.2	0.2	-0.2	-0.1	-0.2	0.0	0.3	0.2	-0.2	-0.3	0.1
Qualifications: None of the above	0.1	0.2	0.5	-0.4	-0.7	0.6	-0.3	-0.2	-0.0	-0.5	-0.2	0.5	-0.5	-0.2	-0.5	-0.3	-0.5	-0.5	0.2
Pain all over the body in last month	0.1	0.1	1.4	0.1	-1.2	0.1	-0.1	-0.0	-0.2	0.2	-0.3	0.3	-0.1	0.2	0.2	0.2	0.1	0.0	-0.0
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	2.4	1.6	-0.9	0.9	-0.4	-0.5	-0.1	0.2	-1.3	-0.4	-0.5	-0.0	0.3	0.2	-0.2	-0.4	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.6	-0.8	0.3	-0.1	0.1	0.2	-0.4	0.0	0.4	-0.5	0.3	0.0	0.2	-0.1	0.3	0.4	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	1.5	1.2	-0.6	0.8	-0.1	-0.1	-0.1	0.4	-0.4	-0.2	-0.1	0.1	0.4	0.3	0.0	-0.1	-0.0
Arm fat mass (right)	0.1	0.4	1.1	-0.3	-1.0	0.9	0.5	0.7	0.5	0.6	0.6	0.5	0.6	0.5	0.6	0.6	0.4	0.5	0.7
Length of working week for main job	0.1	0.1	0.4	0.2	0.5	0.1	0.1	-0.0	0.1	-0.0	-0.1	-0.1	0.2	0.1	0.7	-0.1	0.2	0.3	0.0
Tense / ‘highly strung’	0.1	0.2	1.4	1.2	0.3	0.9	-0.1	-0.1	-0.2	0.2	-0.6	-0.2	-0.2	0.1	0.5	0.2	0.1	-0.1	-0.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.8	-0.2	-0.8	0.1	-0.0	0.1	-0.3	-0.3	0.9	-0.2	0.2	-0.4	-0.7	-0.3	-0.2	-0.0	0.0
Glaucoma (self-reported)	0.1	0.1	0.7	0.2	-0.6	0.0	-0.2	-0.4	-0.4	-0.2	0.0	-0.8	-0.2	-0.2	0.4	-0.2	-0.0	-0.0	-0.5
Medication: Amlodipine	0.1	0.2	1.0	0.4	-0.1	0.4	0.5	0.8	0.5	0.3	-0.0	0.2	0.2	0.5	0.2	0.5	0.4	0.2	1.0
Leg fat percentage (right)	0.1	0.4	2.2	-1.5	-1.2	0.6	0.2	0.6	0.3	-0.0	1.1	0.5	0.4	0.0	0.0	0.0	0.1	0.2	0.7
Number of children fathered	0.1	0.2	1.2	0.4	-0.2	1.1	-0.3	-0.1	0.2	-0.2	-0.6	-0.5	0.0	-0.1	0.3	-0.3	-0.1	0.1	-0.2
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.6	0.5	0.2	-0.1	0.1	0.2	-0.1	0.1	-0.1	-0.0	-0.0	-0.3	-0.1	-0.1	-0.1	0.3
Diabetes diagnosed by doctor	0.1	0.1	0.7	0.8	-0.5	-0.1	-0.3	-0.1	-0.6	-0.1	-0.8	0.0	-0.2	-0.0	0.2	-0.1	-0.1	-0.1	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.9	-0.7	0.9	-0.1	-0.1	0.1	-0.2	-0.2	0.2	-0.1	0.1	-0.2	-0.3	-0.3	-0.1	0.0	-0.0
Eye problems/disorders: Cataract	0.1	0.1	0.2	0.4	-0.1	-0.2	0.3	0.1	-0.1	0.1	0.3	0.4	0.4	0.1	0.3	0.1	0.2	0.3	-0.1
Arm fat mass (left)	0.1	0.4	1.0	-0.3	-0.8	1.0	0.5	0.7	0.7	0.6	0.3	0.6	0.7	0.6	0.7	0.6	0.5	0.6	0.8
Illnesses of father: High blood pressure	0.1	0.2	0.9	0.7	-0.5	-0.9	-0.1	0.2	0.2	0.2	0.6	0.4	-0.3	-0.1	-0.2	0.3	-0.3	-0.5	0.3
Supplements: Calcium	0.1	0.1	0.5	0.3	0.4	-0.7	0.1	0.1	-0.5	0.1	0.1	-0.4	0.0	0.1	0.0	0.1	0.2	0.2	-0.1
Hair Pigment	0.0	0.8	1.4	0.4	0.6	0.9	1.0	1.1	0.6	0.9	1.1	1.2	1.0	0.8	0.9	1.0	0.9	0.9	0.9
Tanning	0.0	0.4	4.5	-0.4	-0.6	-0.1	0.5	0.5	-0.0	0.0	2.1	0.3	0.6	-0.1	-0.7	0.1	0.1	0.3	0.3
Diabetes (mother)	0.0	0.1	0.3	0.4	0.2	-0.1	0.0	0.2	-0.0	-0.3	0.2	0.4	-0.0	-0.1	-0.5	-0.2	-0.1	-0.1	0.1
Impedance of leg (left)	0.0	0.2	1.4	-1.2	0.1	-0.2	-0.2	-0.2	-0.1	-0.6	0.1	-0.4	-0.2	-0.3	-0.5	-0.6	-0.2	-0.1	-0.1
Osteoarthritis (self-reported)	0.0	0.0	0.2	0.4	-0.0	-0.1	-0.1	0.1	-0.1	-0.0	0.4	0.1	-0.1	-0.1	-0.1	-0.0	-0.1	-0.1	0.0
Medication: Lisinopril	0.0	0.1	0.3	0.4	0.2	-0.5	-0.2	-0.0	-0.3	-0.3	-0.1	-0.2	-0.1	-0.3	-0.0	-0.3	-0.2	-0.2	-0.1

Hub : Genes

SPATA24

Models

Trait associations