[Hub]/) : Traits : Trunk predicted mass :

chr5:136,723,696-141,087,689

Best TWAS P=2.11e-14 · Best GWAS P=1e-17 conditioned to 0.00684

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC18 0.09 0.10 bslmm 260 0.10 2.5e-12 4.5 6.3 2.6e-10 0.64 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex FAM53C 0.05 0.02 bslmm 291 0.03 4.1e-04 7.3 5.6 2.7e-08 0.03 0.04 0.89 FALSE
3 CommonMind Brain Pre-frontal Cortex PCDHA2 0.04 0.03 blup 478 0.03 5.0e-05 -4.6 -5.2 1.7e-07 -0.05 0.07 0.90 FALSE
4 CommonMind Brain Pre-frontal Cortex SPATA24 0.05 0.03 lasso 3 0.04 1.4e-05 4.9 5.2 2.0e-07 0.53 0.54 0.03 FALSE
5 GTEx Artery Tibial TMEM173 0.24 0.14 lasso 3 0.13 1.2e-10 5.0 -5.3 1.1e-07 -0.43 1.00 0.00 FALSE
6 GTEx Artery Tibial PROB1 0.06 0.09 enet 10 0.08 5.9e-07 5.0 -6.1 1.0e-09 -0.62 0.78 0.16 FALSE
7 GTEx Cells EBV-transformed lymphocytes DNAJC18 0.26 0.09 lasso 2 0.12 9.7e-05 5.0 6.6 3.8e-11 0.77 0.04 0.85 FALSE
8 GTEx Cells Transformed fibroblasts CD14 0.09 0.05 lasso 4 0.06 2.7e-05 -3.8 -5.2 1.5e-07 -0.01 0.20 0.67 FALSE
9 GTEx Cells Transformed fibroblasts DNAJC18 0.28 0.14 lasso 5 0.11 1.4e-08 5.0 5.2 1.8e-07 0.59 0.99 0.00 FALSE
10 GTEx Colon Transverse TMCO6 0.15 0.06 enet 16 0.05 1.4e-03 4.3 -5.3 8.6e-08 -0.05 0.13 0.53 FALSE
11 GTEx Colon Transverse DNAJC18 0.37 -0.01 lasso 5 0.01 1.1e-01 5.0 6.2 4.2e-10 0.59 0.06 0.07 FALSE
12 GTEx Esophagus Gastroesophageal Junction DNAJC18 0.17 0.01 lasso 10 0.04 2.0e-02 5.1 7.4 1.2e-13 0.77 0.06 0.67 FALSE
13 GTEx Esophagus Mucosa DNAJC18 0.22 0.17 lasso 2 0.16 5.1e-11 5.0 5.4 8.3e-08 0.58 1.00 0.00 FALSE
14 GTEx Esophagus Mucosa TMEM173 0.10 0.03 enet 20 0.10 1.8e-07 8.5 -6.3 2.3e-10 -0.39 0.05 0.76 FALSE
15 GTEx Esophagus Muscularis DNAJC18 0.22 0.10 lasso 6 0.13 3.2e-08 5.0 6.5 9.9e-11 0.59 0.55 0.12 TRUE
16 GTEx Esophagus Muscularis TMEM173 0.24 0.00 lasso 6 0.06 1.5e-04 4.9 -6.0 2.0e-09 -0.55 0.70 0.14 FALSE
17 GTEx Lung PROB1 0.15 0.12 lasso 11 0.10 2.2e-08 5.0 -5.2 1.5e-07 -0.59 0.98 0.01 FALSE
18 GTEx Muscle Skeletal DNAJC18 0.44 0.33 lasso 7 0.34 5.5e-34 5.0 5.2 2.0e-07 0.60 1.00 0.00 FALSE
19 GTEx Nerve Tibial HARS 0.07 0.01 enet 16 0.04 1.1e-03 -4.6 5.7 1.2e-08 -0.04 0.08 0.83 TRUE
20 GTEx Ovary DNAJC18 0.33 0.24 lasso 3 0.21 7.1e-06 5.0 5.3 1.1e-07 0.59 0.08 0.09 FALSE
21 GTEx Pituitary FAM53C 0.28 0.09 lasso 5 0.02 8.2e-02 4.6 5.2 1.7e-07 0.06 0.12 0.08 FALSE
22 GTEx Skin Sun Exposed Lower leg WDR55 0.04 0.01 enet 10 0.01 2.8e-02 -4.5 -5.5 4.9e-08 0.01 0.08 0.77 FALSE
23 GTEx Spleen DNAJC18 0.30 0.13 lasso 5 0.20 6.5e-06 5.0 6.1 1.1e-09 0.77 0.10 0.65 FALSE
24 GTEx Thyroid DNAJC18 0.38 0.26 lasso 4 0.26 1.5e-19 5.0 5.2 2.2e-07 0.58 1.00 0.00 FALSE
25 GTEx Vagina PURA 0.52 0.05 enet 51 0.09 3.6e-03 5.1 -5.6 2.5e-08 -0.13 0.06 0.10 FALSE
26 METSIM Adipose PROB1 0.04 0.02 enet 23 0.02 2.9e-04 4.5 -5.5 3.7e-08 -0.57 0.92 0.01 FALSE
27 ROSMAP Brain Pre-frontal Cortex WNT8A 0.05 0.01 blup 300 0.03 1.0e-04 -2.4 -6.7 2.3e-11 0.00 0.14 0.78 FALSE
28 ROSMAP Brain Pre-frontal Cortex KDM3B 0.07 0.01 blup 307 0.03 1.0e-04 4.9 -5.6 2.3e-08 -0.09 0.24 0.60 FALSE
29 ROSMAP Brain Pre-frontal Cortex PROB1 0.12 0.09 lasso 6 0.10 7.7e-13 5.0 -5.7 1.5e-08 -0.62 1.00 0.00 FALSE
30 YFS Blood CXXC5 0.01 0.00 bslmm 244 0.01 2.6e-03 8.5 -6.5 6.5e-11 -0.48 0.03 0.66 FALSE
31 YFS Blood TMCO6 0.01 0.00 blup 329 0.01 4.1e-03 -4.4 -5.2 1.8e-07 0.02 0.09 0.86 FALSE
32 The Cancer Genome Atlas Bladder Urothelial Carcinoma DNAJC18 0.03 0.02 blup 22 0.02 6.9e-03 5.0 5.2 2.5e-07 0.60 0.03 0.44 FALSE
33 The Cancer Genome Atlas Breast Invasive Carcinoma MGC29506 0.01 0.00 blup 24 0.00 3.6e-02 5.0 -5.3 9.5e-08 -0.58 0.01 0.38 FALSE
34 The Cancer Genome Atlas Breast Invasive Carcinoma TMEM173 0.02 0.03 blup 7 0.03 4.6e-07 4.9 -5.9 4.7e-09 -0.56 0.07 0.92 FALSE
35 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DNAJC18 0.06 0.05 lasso 2 0.04 7.3e-03 5.0 5.1 2.8e-07 0.59 0.01 0.60 FALSE
36 The Cancer Genome Atlas Esophageal Carcinoma SPATA24 0.08 0.08 blup 25 0.08 1.5e-03 4.6 5.3 9.1e-08 0.60 0.04 0.56 FALSE
37 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma UBE2D2 0.05 0.02 enet 6 0.03 4.4e-04 5.3 7.6 2.1e-14 0.91 0.01 0.97 TRUE
38 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma BRD8 0.12 0.07 lasso 4 0.05 1.2e-03 7.0 -6.7 1.7e-11 0.00 0.00 0.98 TRUE
39 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma DNAJC18 0.06 0.02 blup 23 0.02 9.5e-03 5.0 5.5 3.4e-08 0.60 0.02 0.46 FALSE
40 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SPATA24 0.03 0.02 blup 24 0.03 2.8e-03 4.5 5.2 1.7e-07 0.59 0.03 0.26 FALSE
41 The Cancer Genome Atlas Pancreatic Adenocarcinoma DNAJC18 0.07 0.09 blup 24 0.09 1.9e-04 5.0 5.2 2.2e-07 0.60 0.11 0.67 FALSE
42 The Cancer Genome Atlas Stomach Adenocarcinoma SLC23A1 0.04 0.02 blup 28 0.03 4.3e-03 5.2 -5.2 2.0e-07 -0.50 0.01 0.70 FALSE
43 The Cancer Genome Atlas Thyroid Carcinoma DNAJC18 0.08 0.10 blup 23 0.10 3.7e-10 4.8 5.6 2.5e-08 0.62 0.50 0.50 FALSE