[Hub]/) : Traits : Trunk predicted mass : ← →

chr1:154,282,146-155,910,830

Best TWAS P=7.14e-38 · Best GWAS P=1.92e-34 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Skin Sun Exposed Lower leg	ADAM15	0.14	0.09	lasso	4	0.08	6.1e-07	12.24	-12.9	7.1e-38	-0.96	0.00	1.00	TRUE
2	GTEx	Brain Nucleus accumbens basal ganglia	DCST2	0.28	0.04	lasso	5	0.13	2.0e-04	12.24	7.8	4.5e-15	0.69	0.02	0.90	TRUE
5	GTEx	Esophagus Mucosa	MUC1	0.17	0.20	lasso	4	0.18	5.6e-12	-7.46	-7.0	2.8e-12	-0.12	1.00	0.00	TRUE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	GBA	0.05	0.01	lasso	2	0.01	2.3e-02	8.01	-6.9	6.1e-12	-0.07	0.00	0.86	TRUE
9	GTEx	Testis	MUC1	0.20	0.02	lasso	7	0.07	7.5e-04	-7.55	-6.5	7.4e-11	-0.11	0.27	0.05	TRUE
4	GTEx	Esophagus Mucosa	ADAM15	0.11	0.02	enet	16	0.04	1.5e-03	-5.35	-6.0	1.7e-09	-0.43	0.13	0.78	TRUE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ADAM15	0.09	0.00	blup	49	0.02	3.6e-02	-0.72	-5.9	3.8e-09	-0.43	0.01	0.09	TRUE
10	GTEx	Thyroid	DCST2	0.16	0.12	lasso	2	0.11	6.4e-09	-3.55	5.5	2.9e-08	0.53	0.38	0.62	TRUE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM46	0.03	0.01	blup	32	0.01	4.9e-03	-7.40	-5.2	2.3e-07	-0.11	0.01	0.09	TRUE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZBTB7B	0.05	0.06	lasso	2	0.05	1.8e-06	12.24	-12.2	2.0e-34	-1.00	0.00	1.00	FALSE
1	GTEx	Brain Cerebellar Hemisphere	DCST2	0.45	0.10	lasso	6	0.16	6.6e-05	-3.55	8.9	3.6e-19	0.75	0.01	0.96	FALSE
6	GTEx	Pancreas	RP11-263K19.4	0.22	0.06	enet	23	0.05	3.1e-03	2.10	-7.5	4.4e-14	-0.43	0.06	0.49	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	SLC50A1	0.06	0.02	bslmm	331	0.03	4.3e-05	-7.46	-6.8	9.4e-12	-0.27	0.65	0.04	FALSE
11	NTR	Blood	ZBTB7B	0.02	0.02	lasso	1	0.01	5.4e-05	6.56	6.6	5.5e-11	0.67	0.87	0.03	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	ADAM15	0.15	0.02	blup	49	0.08	1.4e-05	7.43	-6.5	6.3e-11	-0.34	0.03	0.04	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAG1AP1	0.07	0.00	blup	76	0.00	2.9e-01	-3.55	-6.4	1.5e-10	-0.17	0.02	0.08	FALSE
3	GTEx	Breast Mammary Tissue (Female)	FAM189B	0.05	-0.01	lasso	2	0.00	4.8e-01	-6.40	6.4	1.7e-10	0.09	0.04	0.07	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MUC1	0.04	0.01	enet	4	0.02	1.3e-03	-7.46	-6.2	7.1e-10	-0.15	0.03	0.27	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM46	0.03	0.00	blup	33	0.02	3.6e-03	-7.46	-5.9	4.6e-09	-0.11	0.03	0.11	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	GBAP1	0.15	0.06	lasso	4	0.06	3.6e-04	-7.55	5.8	5.2e-09	0.11	0.54	0.04	FALSE