[Hub]/) : Traits : Wheeze or whistling in the chest in last year :

chr20:61,576,647-62,912,463

Best TWAS P=6.27e-10 · Best GWAS P=7.27e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFRP1 0.07 0.07 lasso 3 0.06 5.3e-08 -6.2 6.2 6.3e-10 -0.97 0.01 0.99 TRUE
2 CommonMind Brain Pre-frontal Cortex STMN3 0.07 0.02 lasso 4 0.05 2.8e-06 -5.5 -5.4 7.8e-08 0.74 0.02 0.98 FALSE
3 GTEx Brain Cortex STMN3 0.25 0.09 lasso 7 0.11 6.8e-04 -5.4 -5.7 1.5e-08 0.73 0.10 0.68 FALSE
4 GTEx Testis RTEL1 0.19 0.06 lasso 5 0.14 8.0e-07 -5.4 -5.5 3.4e-08 0.63 0.11 0.77 FALSE
5 YFS Blood LIME1 0.12 0.19 enet 15 0.19 5.3e-59 -5.8 -5.9 3.6e-09 0.96 0.02 0.98 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma STMN3 0.02 0.02 blup 43 0.02 1.7e-03 -5.4 -5.5 3.9e-08 0.65 0.01 0.92 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TNFRSF6B 0.03 0.01 blup 44 0.02 7.1e-04 -5.2 -5.2 2.0e-07 0.74 0.04 0.85 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC2A4RG 0.03 0.01 blup 48 0.02 2.4e-03 -5.2 5.8 8.3e-09 -0.68 0.06 0.52 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma LIME1 0.02 0.03 blup 47 0.02 6.2e-03 -5.4 -6.1 1.4e-09 0.82 0.03 0.58 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma TNFRSF6B 0.02 0.01 enet 7 0.01 6.9e-03 -5.1 -6.0 2.2e-09 0.92 0.01 0.91 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma STMN3 0.07 0.01 blup 41 0.05 4.2e-04 -4.7 -5.3 1.2e-07 0.58 0.04 0.68 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma ARFRP1 0.03 0.02 lasso 2 0.02 1.2e-03 -6.2 6.1 8.7e-10 -1.00 0.00 0.97 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma LIME1 0.04 0.05 blup 47 0.05 9.0e-06 -5.7 -5.9 3.0e-09 0.95 0.01 0.99 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma ZGPAT 0.05 0.06 lasso 3 0.06 5.5e-07 -5.5 5.8 8.6e-09 -0.84 0.06 0.93 FALSE
15 The Cancer Genome Atlas Testicular Germ Cell Tumors LIME1 0.10 0.02 blup 47 0.04 1.5e-02 -5.7 -5.3 1.0e-07 0.89 0.01 0.61 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma ARFRP1 0.04 0.00 blup 51 0.00 1.3e-01 -5.8 5.4 8.4e-08 -0.81 0.01 0.56 FALSE