[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr11:46,570,859-48,783,497

Best TWAS P=1.38e-10 · Best GWAS P=4.72e-10 conditioned to 0.00796

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AGBL2 0.03 0.02 enet 7 0.03 7.9e-05 -5.3 -5.5 3.3e-08 0.91 0.04 0.96 FALSE
2 CommonMind Brain Pre-frontal Cortex PTPRJ 0.06 0.04 lasso 4 0.05 7.6e-07 -5.7 -6.2 7.7e-10 0.85 0.03 0.97 FALSE
3 GTEx Brain Cerebellar Hemisphere RP11-750H9.5 0.17 0.25 lasso 6 0.21 3.5e-06 5.2 -5.2 2.1e-07 0.31 0.39 0.15 FALSE
4 GTEx Breast Mammary Tissue (Female) ACP2 0.03 0.00 lasso 1 0.02 1.0e-01 -6.1 6.1 1.0e-09 -1.00 0.02 0.23 FALSE
5 GTEx Cells EBV-transformed lymphocytes ACP2 0.17 0.03 lasso 6 0.03 4.2e-02 -3.0 6.4 1.4e-10 -0.66 0.08 0.79 TRUE
6 GTEx Esophagus Gastroesophageal Junction NUP160 0.18 0.02 enet 18 0.11 7.1e-05 2.6 -5.5 4.3e-08 0.28 0.26 0.08 FALSE
7 GTEx Esophagus Mucosa ACP2 0.07 0.04 enet 11 0.04 6.2e-04 -5.3 5.5 3.7e-08 -0.75 0.04 0.95 FALSE
8 GTEx Muscle Skeletal FNBP4 0.05 0.03 lasso 5 0.04 5.0e-05 -5.4 -6.0 2.5e-09 0.79 0.09 0.86 FALSE
9 GTEx Nerve Tibial CELF1 0.08 0.02 enet 15 0.06 4.3e-05 4.6 -5.2 1.7e-07 0.28 0.18 0.19 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic SLC39A13 0.07 0.11 lasso 2 0.10 5.2e-06 -5.4 -5.4 6.7e-08 0.94 0.12 0.69 FALSE
11 METSIM Adipose NR1H3 0.03 0.03 lasso 6 0.04 4.7e-06 5.0 -6.1 8.3e-10 0.45 0.17 0.77 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma PSMC3 0.09 0.05 blup 39 0.05 1.0e-03 5.2 -5.2 2.2e-07 0.37 0.06 0.37 FALSE