TWAS hub - TOMM22

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1530	0.0290	0.0e+00	0.265	0.266	0.266	0.266	0.272	3.6e-32	2.4e-32	2.7e-32	2.9e-32	4.0e-33
2	GTEx	Adipose Subcutaneous	0.1050	0.0430	1.4e-03	0.023	NA	0.004	NA	0.008	5.4e-03	NA	1.4e-01	NA	6.5e-02
3	GTEx	Artery Tibial	0.0654	0.0260	1.4e-04	0.099	NA	0.082	NA	0.094	3.5e-08	NA	5.6e-07	NA	8.2e-08
4	GTEx	Brain Cerebellar Hemisphere	0.3690	0.1120	1.1e-03	-0.007	NA	-0.012	NA	-0.009	5.2e-01	NA	9.7e-01	NA	6.5e-01
5	GTEx	Esophagus Mucosa	0.0970	0.0460	3.4e-03	0.023	NA	0.015	NA	0.009	1.1e-02	NA	3.2e-02	NA	7.9e-02
6	GTEx	Lung	0.0454	0.0206	3.1e-03	0.044	NA	0.042	NA	0.036	2.7e-04	NA	3.7e-04	NA	9.0e-04
7	GTEx	Muscle Skeletal	0.0313	0.0149	5.7e-03	0.022	NA	0.005	NA	0.012	2.7e-03	NA	8.6e-02	NA	2.2e-02
8	GTEx	Nerve Tibial	0.1109	0.0404	4.7e-05	0.083	NA	0.051	NA	0.075	1.6e-06	NA	1.5e-04	NA	5.2e-06
9	GTEx	Pancreas	0.0970	0.0440	1.7e-03	0.080	NA	0.078	NA	0.088	2.8e-04	NA	3.5e-04	NA	1.4e-04
10	GTEx	Skin Not Sun Exposed Suprapubic	0.1280	0.0440	8.0e-06	0.108	NA	0.107	NA	0.114	1.6e-06	NA	1.8e-06	NA	7.9e-07
11	GTEx	Skin Sun Exposed Lower leg	0.0700	0.0250	8.5e-05	0.074	NA	0.043	NA	0.067	9.9e-07	NA	1.6e-04	NA	3.2e-06
12	GTEx	Testis	0.1050	0.0560	9.7e-03	0.000	NA	0.013	NA	-0.002	3.3e-01	NA	8.4e-02	NA	3.9e-01
13	GTEx	Thyroid	0.0650	0.0250	2.9e-04	0.089	NA	0.036	NA	0.065	2.6e-07	NA	8.2e-04	NA	9.8e-06
14	TCGA	Breast Invasive Carcinoma	0.0224	0.0177	2.3e-04	0.013	0.012	0.012	NA	0.012	9.3e-04	1.4e-03	1.1e-03	NA	1.3e-03
15	TCGA	Lung Adenocarcinoma	0.0207	0.0144	2.0e-03	0.021	0.020	0.015	NA	0.019	1.4e-03	1.7e-03	6.4e-03	NA	2.2e-03
16	TCGA	Pancreatic Adenocarcinoma	0.0730	0.0520	1.8e-03	0.033	0.040	0.009	NA	0.025	1.6e-02	8.8e-03	1.3e-01	NA	3.0e-02
17	TCGA	Thyroid Carcinoma	0.0610	0.0540	4.0e-05	0.036	0.030	0.023	NA	0.039	1.9e-04	5.8e-04	2.5e-03	NA	1.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Pulse rate, automated reading	21.0	67.8	82.4	9.1	9.1	8.4	5.8	5.8	7.5	8.4	8.9	8.8	8.8	9.0	6.5	8.3	7.9	8.8	8.9	8.9
Heel T-Score	18.4	146.1	176.9	12.7	12.9	12.6	9.6	8.4	13.3	13.0	12.9	12.1	13.1	12.4	9.2	12.3	11.2	12.9	12.3	13.1
Pulse rate	15.0	25.3	30.9	5.3	5.4	5.1	2.8	4.4	4.5	5.0	5.6	5.5	5.2	5.5	4.5	5.0	5.3	5.2	5.5	5.2
Ever used hormone-replacement therapy (HRT)	10.4	13.2	17.3	-4.1	-4.1	-4.1	-1.3	-1.0	-2.9	-4.2	-3.7	-4.1	-3.8	-4.1	-2.8	-4.0	-3.7	-4.0	-4.1	-3.6
Diverticular disease/diverticulitis (self-reported)	10.3	12.2	17.4	-3.8	-3.7	-3.6	-2.3	-2.6	-3.2	-3.4	-4.2	-3.7	-3.8	-3.7	-2.5	-3.5	-3.3	-3.7	-3.7	-3.9
Medication for hormone replacement therapy	9.8	11.0	15.2	-3.9	-3.6	-3.2	-1.3	-1.8	-3.1	-3.7	-3.3	-3.7	-3.5	-3.8	-1.3	-3.9	-3.6	-3.7	-3.9	-3.4
Depressed Affect (Nagel 2018)	8.6	18.2	29.2	-4.5	-4.3	-5.4	-3.2	-3.3	-3.5	-4.9	-4.5	-4.4	-4.4	-4.5	-2.2	-4.8	-3.9	-4.5	-4.5	-4.5
Number of children fathered	8.1	9.2	12.7	3.4	3.1	2.7	2.4	1.7	3.0	3.1	3.3	3.0	3.2	3.2	3.6	3.0	2.8	3.2	3.2	3.1
Heel bone mineral density (BMD) T-score, automated (left)	7.7	17.5	25.3	4.3	4.3	4.3	3.4	3.2	5.0	4.6	4.1	4.2	4.5	4.2	3.1	4.3	4.0	4.4	4.2	4.5
Fractured/broken bones in last 5 years	7.6	9.9	14.3	-3.4	-3.6	-2.7	-0.7	-2.4	-2.7	-3.2	-3.2	-3.8	-2.9	-3.6	-2.5	-3.1	-3.8	-3.4	-3.6	-3.4
Heel bone mineral density (BMD) T-score, automated (right)	7.5	17.2	26.9	4.3	4.4	4.1	3.7	2.7	5.2	4.6	4.2	4.1	4.5	4.2	2.4	4.0	3.9	4.5	4.2	4.6
Alcohol intake versus 10 years previously	7.3	10.9	14.7	-3.7	-3.4	-2.9	-3.4	-1.7	-3.1	-3.5	-3.4	-3.5	-3.6	-3.6	-1.9	-3.4	-3.2	-3.7	-3.5	-3.8
Alcohol intake frequency.	7.3	17.1	22.4	-4.4	-4.3	-4.0	-3.4	-2.5	-4.7	-4.4	-4.3	-4.3	-4.4	-4.3	-2.9	-4.2	-4.3	-4.5	-4.3	-4.5
Financial difficulties in last 2 years	7.2	9.6	12.2	-3.1	-3.2	-3.5	-3.3	-2.9	-1.6	-3.3	-3.0	-3.0	-3.2	-3.2	-2.9	-3.3	-2.9	-3.3	-3.2	-3.4
Overall health rating	7.2	15.4	20.0	-4.3	-4.2	-3.5	-2.2	-2.1	-3.7	-4.3	-4.5	-4.3	-3.8	-4.3	-2.7	-4.4	-4.3	-4.2	-4.3	-4.3
Neuroticism (Nagel 2018)	5.9	13.8	23.7	-4.0	-3.7	-4.9	-2.3	-2.3	-2.8	-4.4	-4.1	-3.9	-3.7	-3.9	-1.8	-4.4	-3.7	-3.9	-3.9	-3.8
Long-standing illness, disability or infirmity	5.7	8.8	13.0	-3.2	-3.4	-3.2	1.1	-0.6	-2.4	-3.3	-3.6	-3.6	-2.8	-3.3	-2.6	-3.3	-3.0	-3.1	-3.3	-2.8
Rheumatoid Arthritis	5.6	7.7	12.5	-2.6	-2.8	-2.9	-2.1	-2.4	-3.4	-3.0	-2.4	-2.6	-2.9	-2.6	-3.5	-2.5	-2.7	-2.8	-2.6	-2.9
Hip circumference	5.6	23.9	33.4	-5.1	-5.0	-4.5	-3.6	-3.7	-5.3	-5.0	-5.8	-5.0	-5.1	-5.1	-4.6	-4.8	-4.5	-5.2	-4.9	-5.4
Happiness	5.6	6.8	12.0	-2.5	-2.9	-3.1	-0.2	-3.5	-2.3	-2.9	-2.4	-2.7	-2.6	-2.5	-0.9	-3.0	-2.9	-2.6	-2.6	-2.6
Townsend deprivation index at recruitment	5.1	7.2	9.5	-2.8	-2.8	-2.8	-1.9	-1.8	-1.8	-2.9	-2.9	-2.9	-2.9	-3.0	-2.6	-2.7	-2.4	-3.0	-2.9	-3.1
Back pain experienced in last month	5.1	7.5	10.8	-3.0	-2.8	-3.1	-2.1	-1.6	-2.1	-3.3	-2.5	-2.8	-2.9	-2.8	-1.0	-3.2	-3.2	-3.0	-2.9	-3.0
Triglycerides	5.0	8.1	12.6	-3.1	-3.0	-3.0	-0.2	0.6	-3.0	-3.3	-3.0	-3.1	-3.0	-2.9	-1.9	-3.5	-3.3	-3.1	-3.3	-2.7
Suffer from ‘nerves’	4.9	7.7	11.6	-3.2	-3.0	-3.4	-2.3	-1.3	-2.0	-3.1	-3.0	-2.7	-3.1	-3.0	-1.4	-3.3	-2.1	-3.1	-2.8	-3.1
Leg pain on walking	4.9	6.1	8.0	-2.7	-2.5	-2.6	-2.6	-2.5	-1.3	-2.8	-2.3	-2.6	-2.4	-2.7	-0.5	-2.8	-2.5	-2.6	-2.6	-2.7
Length of working week for main job	4.8	5.4	8.1	-2.4	-2.5	-2.4	-0.5	-1.6	-2.6	-2.4	-2.8	-2.3	-2.4	-2.2	-1.4	-2.5	-2.7	-2.5	-2.4	-2.6
Commuting to job workplace: Car/motor vehicle	4.7	5.4	7.9	2.5	2.6	1.8	1.6	1.4	2.5	2.4	2.5	2.7	2.8	2.7	-0.2	2.0	2.4	2.6	2.6	2.6
Alzheimer’s Disease (in mother)	4.5	5.2	10.5	2.4	2.2	2.6	1.7	0.4	2.3	2.6	1.7	2.1	2.4	2.2	3.2	2.4	2.2	2.5	2.3	2.3
Number of self-reported non-cancer illnesses	4.3	7.4	14.8	-3.1	-3.1	-2.9	0.2	-0.9	-2.0	-2.9	-2.7	-3.3	-2.5	-3.0	-1.3	-3.2	-3.8	-2.8	-3.2	-2.7
Birth weight of first child	4.2	7.7	15.6	-2.6	-3.0	-3.5	-1.5	-3.2	-2.8	-2.8	-2.5	-2.4	-2.3	-2.6	-4.0	-3.1	-2.3	-2.6	-2.6	-2.6
Qualifications: CSEs or equivalent	4.0	5.3	7.9	-2.4	-2.2	-2.6	-2.8	-1.6	-2.0	-2.4	-2.5	-2.2	-2.2	-2.4	-1.7	-2.5	-2.1	-2.4	-2.4	-2.4
Illness, injury, bereavement, stress in last 2 years	4.0	4.9	6.7	2.4	2.4	2.4	0.2	0.5	1.2	2.6	2.4	2.5	2.1	2.4	2.4	2.5	2.3	2.4	2.4	2.2
Ever had stillbirth, spontaneous miscarriage or termination	4.0	4.3	6.0	-2.1	-2.0	-2.1	-2.4	-1.0	-2.4	-2.3	-2.0	-2.0	-2.3	-2.2	-1.6	-2.0	-1.6	-2.2	-2.1	-2.3
Hand grip strength (right)	3.6	9.8	14.2	3.4	3.5	2.9	1.8	1.4	2.9	3.3	3.8	3.6	3.2	3.4	1.9	3.1	3.6	3.4	3.6	3.1
Neuroticism	3.5	8.3	13.7	-3.2	-3.0	-3.7	-2.7	-2.9	-1.7	-3.2	-2.6	-2.8	-2.7	-3.0	-1.3	-3.5	-2.8	-3.0	-3.0	-3.0
Pack years adult smoking proportion	3.5	5.4	7.9	-2.3	-2.2	-2.2	-2.5	-2.0	-2.8	-2.6	-2.1	-2.4	-2.3	-2.4	-0.8	-2.3	-2.2	-2.5	-2.3	-2.8
Mood swings	3.5	6.4	12.6	-2.6	-2.5	-3.6	-1.5	-2.3	-2.5	-3.1	-2.4	-2.4	-2.6	-2.5	-1.4	-3.1	-1.9	-2.6	-2.5	-2.6
Crohns Disease (2012)	3.4	5.6	8.5	2.5	2.3	2.9	1.9	0.6	2.4	2.8	2.8	2.4	2.3	2.2	1.8	2.7	2.5	2.4	2.3	2.4
Fed-up feelings	3.3	5.9	9.6	-2.5	-2.3	-3.1	-1.8	-1.8	-2.0	-2.8	-2.2	-2.7	-2.4	-2.5	-1.2	-2.6	-3.0	-2.5	-2.6	-2.6
Frequency of tenseness / restlessness in last 2 weeks	3.3	5.2	8.9	-2.4	-2.4	-3.0	-1.5	-1.7	-1.5	-2.7	-2.5	-2.3	-2.6	-2.4	-0.2	-2.8	-1.9	-2.5	-2.4	-2.6
Gout (self-reported)	3.3	4.5	6.1	2.3	2.4	1.9	1.9	1.4	2.4	2.3	2.4	2.3	2.4	2.5	0.4	2.1	1.2	2.4	2.2	2.4
Mouth/teeth dental problems: Mouth ulcers	3.3	5.3	9.8	-2.7	-2.0	-2.5	-1.3	0.0	-1.6	-2.6	-2.3	-2.7	-2.1	-2.6	-1.0	-2.6	-3.1	-2.4	-2.7	-2.6
Number of operations (self-reported)	3.3	4.9	7.2	-2.3	-2.6	-2.7	-1.0	-0.9	-2.1	-2.7	-2.3	-2.3	-2.3	-2.2	-1.6	-2.3	-2.2	-2.4	-2.2	-2.4
Crohns Disease (2017)	3.2	7.1	9.9	2.9	2.5	3.1	1.8	0.7	2.5	3.1	3.1	2.7	2.9	2.6	1.9	3.1	3.0	2.8	2.7	2.6
Ever unenthusiastic/disinterested for a whole week	3.2	3.9	6.9	-2.2	-2.0	-2.0	-1.4	-1.0	-2.2	-1.9	-2.6	-1.8	-2.2	-1.9	-2.1	-2.0	-1.8	-2.1	-2.0	-1.9
Primary Biliary Cirrhosis	3.1	4.4	6.0	-2.4	-2.5	-2.5	-0.9	-1.4	-2.2	-2.3	-2.1	-2.2	-2.0	-2.2	-1.3	-2.1	-2.0	-2.2	-2.2	-2.3
Blood Platelet Count	3.1	35.7	42.9	-6.4	-6.3	-6.0	-6.2	-5.0	-5.2	-5.8	-5.2	-5.7	-6.3	-6.2	-5.8	-6.2	-5.8	-6.4	-6.3	-6.5
Time employed in main current job	3.1	3.6	5.3	2.0	2.1	2.3	1.5	1.0	0.8	1.9	2.2	2.1	1.9	2.1	2.0	1.8	2.0	1.9	2.1	1.8
Alzheimer’s Disease (including proxy)	3.0	4.4	12.2	2.3	2.2	2.0	1.3	0.3	2.4	2.1	1.4	2.1	2.1	2.0	3.5	1.9	2.3	2.1	2.1	2.0
Medication: Amlodipine	3.0	4.2	6.4	2.1	1.9	2.1	2.5	0.4	2.1	2.2	2.4	1.9	2.5	2.0	2.0	1.9	1.3	2.3	2.0	2.2
Chest pain or discomfort	3.0	4.3	6.4	-2.1	-1.9	-1.5	-1.6	-1.0	-1.4	-2.3	-2.5	-2.3	-2.3	-2.3	-2.3	-2.1	-1.9	-2.4	-2.2	-2.5
Ever taken oral contraceptive pill	3.0	3.4	7.3	-1.9	-2.2	-2.7	0.2	-1.7	-2.2	-2.2	-1.1	-2.1	-1.5	-2.0	-0.6	-2.3	-1.6	-1.8	-2.0	-1.6
Heart disease (siblings)	3.0	3.7	6.7	1.8	2.1	2.2	1.4	2.3	1.0	1.7	1.9	1.9	1.6	2.0	2.6	1.8	2.0	1.9	2.1	1.9
Medication: Paracetamol	2.9	4.5	6.2	-2.4	-2.2	-2.3	-1.8	0.8	-1.3	-2.3	-2.1	-2.2	-2.1	-2.2	-1.6	-2.4	-2.5	-2.3	-2.3	-2.3
Hand grip strength (left)	2.8	7.4	10.9	2.8	2.9	2.3	1.9	1.0	2.9	3.1	3.3	3.1	3.0	2.9	1.4	2.6	3.1	3.1	3.0	2.9
Family relationship satisfaction	2.8	3.4	6.1	-2.0	-2.2	-2.3	-1.0	-1.5	-1.4	-2.0	-2.5	-1.9	-1.9	-2.1	-0.6	-2.1	-1.2	-2.0	-1.9	-2.0
Allergy	2.7	6.2	12.9	2.7	3.0	2.4	-0.7	0.9	2.2	2.7	2.4	3.2	2.4	2.8	0.8	2.4	3.6	2.6	3.0	2.4
Hypothyroidism/myxoedema (self-reported)	2.7	5.3	7.4	-2.6	-2.7	-2.6	-1.7	0.2	-2.3	-2.7	-2.4	-2.5	-2.4	-2.4	-0.5	-2.6	-2.5	-2.5	-2.5	-2.2
Pulse wave peak to peak time	2.7	3.1	4.6	-2.1	-1.9	-1.6	-1.2	0.3	-1.4	-1.9	-2.1	-2.0	-1.8	-1.9	-1.3	-1.9	-2.1	-1.9	-2.0	-1.8
Hypothyroidism (self reported)	2.6	6.0	8.9	-2.7	-2.8	-2.5	-2.7	-0.9	-2.9	-3.0	-2.5	-2.3	-2.6	-2.4	-0.6	-2.7	-1.9	-2.7	-2.4	-2.6
Taking other prescription medications	2.6	4.0	8.2	-2.2	-2.5	-1.8	0.7	-0.6	-1.4	-1.9	-2.3	-2.6	-1.7	-2.4	-0.4	-1.9	-2.9	-2.0	-2.5	-1.8
Trunk fat mass	2.6	11.0	16.9	-3.1	-3.1	-2.8	-2.3	-4.1	-3.9	-3.0	-3.7	-3.2	-3.1	-3.2	-3.6	-2.9	-3.5	-3.3	-3.2	-3.7
Illnesses of father: Heart disease	2.6	3.6	7.2	1.8	1.7	1.8	2.7	2.3	1.9	2.0	2.2	1.7	2.0	1.8	0.3	1.8	1.6	2.0	1.8	1.9
Had other major operations	2.5	3.1	5.1	-1.8	-2.2	-2.0	-1.5	0.1	-1.6	-2.3	-2.1	-1.7	-1.7	-1.7	-1.1	-1.9	-1.4	-1.9	-1.7	-1.9
Coronary Artery Disease (CAD)	2.4	2.9	9.1	2.2	2.0	2.0	2.4	0.9	0.6	1.7	3.0	2.0	2.5	2.2	0.2	1.4	0.0	0.0	0.0	0.0
Neuroticism score	2.4	5.0	8.2	-2.4	-2.3	-2.9	-1.5	-1.8	-2.0	-2.7	-1.9	-2.3	-2.1	-2.3	-0.5	-2.7	-2.4	-2.3	-2.4	-2.3
Age at last live birth	2.4	3.4	4.6	-1.9	-2.0	-2.1	-1.6	-1.8	-2.0	-1.9	-1.6	-1.8	-1.9	-1.9	-1.8	-2.2	-1.3	-1.8	-1.9	-1.7
Smoking status: Previous	2.4	3.6	9.9	1.6	1.8	2.0	0.6	2.6	2.3	1.8	1.7	1.7	1.7	1.6	3.1	2.0	1.7	1.6	1.6	1.6
Arm fat percentage (left)	2.4	9.5	13.9	-3.0	-3.0	-2.7	-2.3	-3.7	-3.2	-2.8	-3.2	-3.2	-3.0	-3.1	-2.9	-2.8	-3.7	-3.1	-3.1	-3.4
Handedness (chirality/laterality): Left-handed	2.4	2.8	4.7	1.8	1.9	0.9	2.2	0.3	2.0	1.8	1.6	1.6	2.0	1.7	1.7	1.3	1.3	1.9	1.6	2.0
Friendships satisfaction	2.4	3.0	4.5	-1.8	-2.1	-2.0	0.8	-1.1	-1.5	-2.0	-2.1	-2.0	-1.5	-2.0	-0.2	-2.0	-1.6	-1.8	-2.0	-1.7
Unable to work because of sickness or disability	2.4	3.1	4.8	-2.0	-1.7	-1.6	-0.1	-0.7	-2.1	-2.0	-2.2	-2.1	-1.6	-2.1	-1.5	-2.0	-1.6	-1.9	-2.0	-1.7
Number of treatments/medications taken	2.3	4.1	7.8	-2.4	-2.4	-2.1	-0.3	-0.9	-1.7	-2.2	-1.8	-2.4	-1.7	-2.3	0.2	-2.3	-2.8	-2.2	-2.4	-2.0
Weight	2.3	11.1	17.7	-3.1	-3.2	-2.9	-2.7	-3.2	-3.8	-3.2	-4.1	-3.1	-3.3	-3.2	-4.2	-3.0	-2.9	-3.4	-3.1	-3.7
Hair/balding pattern: Pattern 4	2.3	5.6	10.1	-2.0	-2.4	-1.8	-2.1	-2.3	-3.2	-2.4	-2.6	-2.2	-2.5	-2.2	-3.0	-1.9	-2.0	-2.4	-2.1	-2.6
Wheeze or whistling in the chest in last year	2.3	4.0	6.3	-2.2	-2.0	-1.7	-1.6	1.0	-1.4	-2.4	-2.5	-2.3	-2.1	-2.2	-0.2	-1.9	-2.4	-2.3	-2.3	-2.2
Health satisfaction	2.3	3.0	5.6	-1.8	-1.7	-1.6	-1.0	-1.8	-1.4	-1.9	-2.4	-1.8	-1.7	-1.8	0.3	-1.9	-1.8	-1.9	-1.8	-2.0
Heart attack/myocardial infarction (self-reported)	2.3	2.9	9.8	1.8	1.5	1.5	3.1	0.2	2.0	1.7	1.8	1.5	1.8	1.6	1.1	1.4	1.5	1.7	1.6	1.9
Depression (Nagel 2018)	2.2	3.3	7.8	-1.9	-1.8	-2.8	-0.9	-1.2	-0.6	-2.2	-2.4	-1.7	-1.9	-1.9	-0.7	-2.3	-1.4	-1.9	-1.9	-2.0
Diabetes (mother)	2.2	2.8	4.2	-2.0	-2.0	-1.7	-0.9	-0.9	-0.1	-1.7	-1.9	-2.0	-1.7	-2.1	-0.3	-1.8	-1.7	-1.8	-2.0	-1.8
Worry (Nagel 2018)	2.1	4.5	8.2	-2.2	-2.1	-2.9	-0.9	-2.0	-1.5	-2.5	-2.4	-2.1	-2.0	-2.1	-1.5	-2.7	-2.1	-2.1	-2.2	-1.9
Stomach or abdominal pain in last month	2.1	2.7	5.3	-1.8	-1.4	-1.4	-2.2	0.0	-1.3	-1.4	-1.9	-1.5	-1.7	-1.5	-2.3	-1.5	-2.0	-1.6	-1.6	-1.6
Medication: Levothyroxine sodium	2.1	3.6	5.3	-2.1	-2.2	-1.9	-1.1	0.5	-2.2	-2.1	-2.3	-2.1	-1.8	-2.0	-0.4	-1.9	-2.2	-2.0	-2.0	-2.0
Arm fat percentage (right)	2.1	8.2	14.6	-2.8	-2.7	-2.4	-2.3	-3.8	-3.0	-2.6	-2.9	-2.9	-2.7	-2.8	-2.6	-2.5	-3.4	-2.8	-2.8	-3.2
Noisy workplace	2.1	2.6	4.6	-1.8	-2.1	-2.0	-0.7	-0.6	-0.4	-1.5	-1.6	-1.7	-1.5	-1.8	-2.1	-1.6	-1.5	-1.7	-1.8	-1.8
Arm fat mass (right)	2.1	8.8	14.0	-2.8	-2.8	-2.5	-2.8	-3.7	-3.1	-2.6	-3.3	-2.8	-2.9	-2.9	-3.2	-2.5	-3.1	-2.9	-2.8	-3.3
Whole body fat mass	2.1	8.8	13.9	-2.7	-2.7	-2.5	-2.3	-3.7	-3.3	-2.7	-3.4	-2.9	-2.8	-2.8	-3.4	-2.5	-3.2	-2.9	-2.8	-3.3
Miserableness	2.1	3.7	7.3	-2.0	-1.9	-2.7	-2.6	-1.6	-1.0	-2.2	-1.5	-1.7	-1.8	-1.9	-0.2	-2.4	-1.5	-2.0	-1.9	-2.1
Trunk fat percentage	2.0	7.9	16.4	-2.6	-2.6	-2.2	-1.6	-4.1	-3.3	-2.4	-3.0	-2.8	-2.5	-2.7	-2.9	-2.3	-3.5	-2.7	-2.8	-3.1
Pulse wave Arterial Stiffness index	2.0	2.3	3.9	1.8	1.6	1.4	1.1	-0.6	1.0	1.6	1.7	1.7	1.5	1.6	1.0	1.6	2.0	1.6	1.7	1.6
Loneliness, isolation	2.0	2.8	4.3	-1.8	-1.7	-1.7	-0.9	-0.6	-1.9	-2.1	-2.0	-1.9	-1.8	-1.7	-0.7	-1.7	-1.9	-1.8	-1.8	-1.8
Commuting to job workplace: Walk	2.0	2.2	3.5	-1.6	-1.8	-1.3	-1.1	-0.0	-1.6	-1.5	-1.9	-1.7	-1.8	-1.8	0.8	-1.3	-0.9	-1.6	-1.7	-1.4
Medication for cholesterol	2.0	3.1	4.8	1.9	1.7	1.5	0.4	1.2	1.7	2.0	1.4	1.9	1.9	1.8	1.8	2.2	2.0	1.9	1.9	1.8
Arm fat mass (left)	2.0	8.1	12.4	-2.7	-2.6	-2.4	-2.7	-3.5	-2.9	-2.5	-3.2	-2.7	-2.7	-2.8	-3.2	-2.4	-3.0	-2.8	-2.7	-3.2
Waist Hip Ratio (WHR)	1.9	8.4	13.0	3.3	2.7	2.5	3.4	1.9	2.6	3.1	3.1	2.8	3.6	3.1	2.1	2.7	2.0	3.3	2.9	3.4
Chronotype (morning person)	1.9	4.3	6.8	-2.2	-2.2	-2.6	-0.5	-2.2	-2.2	-2.3	-2.1	-2.2	-2.5	-2.2	-0.6	-2.3	-1.6	-2.2	-2.1	-2.0
HDL Cholesterol	1.8	2.9	4.3	1.9	2.1	1.9	-0.1	-0.3	1.6	2.0	1.7	2.1	1.9	1.8	0.4	1.9	2.1	1.9	2.0	1.5
Leg fat-free mass (left)	1.8	9.3	16.2	-2.9	-2.9	-3.0	-3.0	-2.7	-3.3	-3.1	-3.8	-2.7	-3.1	-2.9	-4.0	-2.8	-1.9	-3.1	-2.7	-3.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	4.9	-1.7	-1.5	-2.2	-1.4	-1.2	-0.2	-1.8	-1.7	-1.3	-1.6	-1.6	-1.1	-2.2	-0.9	-1.7	-1.5	-1.7
Leg predicted mass (left)	1.8	9.4	16.0	-2.9	-2.9	-3.0	-2.9	-2.6	-3.4	-3.2	-3.8	-2.8	-3.1	-3.0	-4.0	-2.9	-1.9	-3.1	-2.7	-3.3
Waist circumference	1.8	6.6	9.8	-2.5	-2.6	-2.3	-1.6	-2.0	-2.9	-2.5	-3.1	-2.7	-2.5	-2.6	-2.7	-2.4	-2.9	-2.6	-2.6	-2.9
Lung cancer (father)	1.8	2.2	5.6	-1.6	-1.5	-0.8	-2.4	-0.8	-1.2	-1.6	-1.3	-1.3	-1.6	-1.7	-0.6	-1.3	-0.8	-1.8	-1.5	-2.0
Worry too long after embarrassment	1.8	3.1	4.5	-1.9	-1.7	-1.8	-1.7	-1.4	-1.5	-2.1	-1.9	-1.8	-1.9	-1.7	1.2	-1.9	-1.7	-1.8	-1.7	-1.8
Medication: Ibuprofen	1.8	2.2	3.4	-1.7	-1.5	-1.8	-1.3	-0.4	-0.8	-1.7	-1.1	-1.6	-1.2	-1.6	1.4	-1.8	-1.8	-1.5	-1.7	-1.4
Knee pain experienced in last month	1.8	2.8	6.1	-1.8	-1.6	-1.8	-1.7	-0.5	-0.8	-1.6	-1.5	-1.6	-1.8	-1.8	-2.5	-1.6	-1.6	-1.8	-1.8	-1.8
Pain type(s) experienced in last month: Hip pain	1.8	2.3	3.3	-1.8	-1.8	-1.5	-0.2	-0.4	-1.3	-1.8	-1.5	-1.8	-1.6	-1.7	-0.4	-1.8	-1.6	-1.7	-1.7	-1.5
Pain experienced in last month	1.8	3.1	5.4	2.0	1.7	2.3	1.8	0.3	0.9	2.0	1.3	1.7	1.8	1.8	1.4	2.2	2.0	1.8	1.8	1.8
Major Depression (MDD)	1.7	2.1	5.6	-1.5	-1.4	-1.6	-2.4	-1.0	-1.5	-1.5	-1.3	-1.3	-1.4	-1.4	-0.5	-1.3	-1.4	-1.5	-1.4	-1.7
Breast Cancer	1.7	4.2	24.6	-1.5	-2.0	-2.6	0.9	-5.0	-1.0	-1.8	-0.7	-1.7	-1.1	-1.5	-2.0	-2.3	-2.4	-1.5	-1.8	-1.2
Current tobacco smoking	1.7	2.8	12.4	-1.6	-1.4	-1.5	-3.5	-1.6	-1.2	-1.7	-1.6	-1.3	-1.8	-1.6	-0.3	-1.7	-0.4	-1.7	-1.4	-2.0
Heart attack	1.7	2.2	9.6	1.6	1.1	1.1	3.1	0.0	1.8	1.4	1.5	1.2	1.5	1.3	0.9	1.1	1.2	1.5	1.3	1.6
Medication: Ramipril	1.7	2.2	5.3	1.5	1.5	1.4	1.3	-0.4	0.8	1.4	1.9	1.8	1.6	1.6	0.7	1.0	2.3	1.5	1.7	1.5
Body fat percentage	1.7	6.8	14.4	-2.4	-2.4	-2.1	-1.6	-3.8	-2.9	-2.2	-2.8	-2.6	-2.3	-2.5	-2.7	-2.2	-3.3	-2.5	-2.5	-2.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	3.1	1.5	1.6	0.9	1.6	1.0	1.4	1.3	1.2	1.5	1.3	1.6	1.8	1.4	1.2	1.5	1.5	1.5
Leg fat-free mass (right)	1.7	9.3	15.3	-2.9	-3.0	-3.1	-3.0	-2.4	-3.2	-3.2	-3.8	-2.8	-3.1	-3.0	-3.9	-2.9	-1.9	-3.1	-2.7	-3.3
Medication: Gliclazide	1.7	1.9	3.6	-1.6	-1.5	-0.9	-0.0	-0.3	-1.0	-1.3	-1.8	-1.7	-1.2	-1.7	-0.1	-1.1	-1.9	-1.5	-1.7	-1.7
Ever had prostate specific antigen (PSA) test	1.7	2.0	5.9	1.6	1.1	0.8	1.9	0.2	0.9	1.2	2.4	1.2	1.5	1.4	1.8	1.2	1.2	1.5	1.3	1.6
Pack years of smoking	1.7	2.6	4.0	-1.5	-1.4	-1.6	-2.0	-1.8	-2.0	-1.8	-1.2	-1.6	-1.5	-1.5	-0.4	-1.4	-1.7	-1.7	-1.5	-2.0
Supplements: Zinc	1.6	1.8	3.0	-1.5	-1.6	-1.1	-0.8	-1.2	-0.8	-1.4	-1.4	-1.6	-1.3	-1.7	-0.7	-1.3	-1.2	-1.5	-1.6	-1.3
Past tobacco smoking	1.6	3.0	12.1	-1.3	-1.5	-1.7	0.1	-2.8	-2.3	-1.4	-1.3	-1.4	-1.3	-1.2	-3.5	-1.6	-1.6	-1.2	-1.3	-1.2
Peak expiratory flow (PEF)	1.6	3.6	5.6	2.2	2.2	2.0	0.9	0.0	1.1	2.0	2.1	2.3	1.7	2.2	1.1	2.3	2.4	2.0	2.2	1.9
Medication: Paracetamol	1.6	2.6	4.2	-1.9	-1.6	-2.0	-1.5	1.5	-0.3	-1.8	-1.5	-1.6	-1.6	-1.6	-0.5	-2.1	-1.9	-1.7	-1.7	-1.7
Illnesses of father: None of the above (group 1)	1.6	2.0	8.5	-1.0	-0.8	-0.6	-2.9	-2.6	-1.4	-1.1	-1.3	-1.0	-1.2	-1.1	-1.1	-0.9	-1.0	-1.2	-1.1	-1.3
Smoking status: Current	1.6	2.6	12.2	-1.6	-1.3	-1.4	-3.5	-1.1	-1.1	-1.6	-1.6	-1.2	-1.8	-1.6	0.1	-1.6	-0.4	-1.7	-1.3	-1.9
Leg predicted mass (right)	1.6	8.8	14.8	-2.8	-2.9	-2.9	-2.9	-2.4	-3.2	-3.1	-3.7	-2.7	-3.0	-2.9	-3.8	-2.8	-1.8	-3.0	-2.6	-3.2
Ever depressed for a whole week	1.6	2.0	3.3	-1.4	-1.5	-1.3	-1.8	-0.1	-1.5	-1.7	-1.8	-1.4	-1.8	-1.5	0.6	-1.1	-0.9	-1.6	-1.4	-1.6
Vitamin and mineral supplements	1.5	2.0	4.8	1.6	1.5	1.3	2.2	0.4	1.0	1.7	1.7	1.4	1.5	1.6	0.4	1.2	0.9	1.6	1.4	1.6
Hayfever, allergic rhinitis or eczema	1.5	3.3	6.7	-1.8	-2.2	-1.8	1.5	-0.9	-1.9	-1.9	-1.5	-2.3	-1.6	-2.0	-0.9	-1.5	-2.6	-1.8	-2.1	-1.5
Hair/balding pattern: Pattern 2	1.5	1.9	3.4	-1.7	-1.8	-1.5	-1.7	-0.4	-0.6	-1.1	-1.7	-1.3	-1.4	-1.5	-1.3	-1.7	-0.8	-1.3	-1.5	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	4.9	-1.3	-1.3	-1.1	2.2	0.6	-1.4	-1.3	-1.7	-1.6	-1.0	-1.3	0.1	-1.4	-1.5	-1.1	-1.3	-1.0
Medication: Lisinopril	1.5	2.0	6.1	-1.4	-1.4	-1.4	0.8	-0.7	-1.5	-1.4	-1.4	-1.7	-1.1	-1.3	-1.2	-1.5	-2.5	-1.2	-1.5	-1.2
Basal metabolic rate	1.5	8.2	14.4	-2.7	-2.8	-2.7	-2.7	-2.3	-3.2	-2.9	-3.7	-2.6	-2.9	-2.8	-3.8	-2.6	-1.8	-2.9	-2.5	-3.1
Age started oral contraceptive pill	1.5	1.9	3.1	1.4	1.4	1.5	0.5	1.2	1.7	1.8	1.4	1.6	1.3	1.4	0.6	1.6	1.4	1.4	1.4	1.3
Average weekly spirits intake	1.4	1.8	3.3	1.4	1.2	1.2	-0.1	-0.1	1.4	1.6	1.8	1.6	1.4	1.3	-0.5	1.4	1.8	1.4	1.4	1.4
Falls in the last year	1.4	1.9	4.1	-1.5	-1.4	-1.5	0.3	-2.0	-0.3	-1.2	-1.5	-1.5	-1.1	-1.5	-1.3	-1.4	-1.4	-1.3	-1.5	-1.4
Qualifications: A levels/AS levels or equivalent	1.4	3.0	6.1	-1.9	-1.8	-1.5	0.8	-1.7	-2.5	-1.7	-2.0	-1.9	-1.8	-1.7	-1.4	-2.0	-1.6	-1.6	-1.8	-1.3
Comparative height size at age 10	1.4	7.5	15.4	-2.5	-2.5	-2.3	-1.8	-3.9	-3.6	-2.8	-3.3	-2.5	-2.8	-2.7	-2.6	-2.6	-1.6	-2.7	-2.4	-3.0
Had major operations	1.4	1.7	3.4	-1.3	-1.6	-1.8	-1.3	-1.3	-0.8	-1.2	-1.2	-1.2	-1.2	-1.3	-1.0	-1.3	-1.3	-1.2	-1.3	-1.3
Average weekly fortified wine intake	1.3	1.5	4.1	-0.9	-0.7	-1.1	-1.7	-2.0	-2.0	-1.4	-0.4	-0.7	-1.1	-0.5	-1.7	-1.2	-1.2	-1.0	-0.7	-1.0
Serious illness, injury or assault to yourself	1.3	1.5	3.8	-1.2	-1.3	-0.5	-0.7	-0.5	-1.9	-1.4	-1.3	-1.1	-1.4	-1.1	-1.7	-1.1	-1.2	-1.4	-1.1	-1.3
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	4.3	-1.4	-1.1	-1.6	-0.9	-0.3	-0.2	-1.5	-0.8	-1.4	-1.0	-1.4	2.1	-1.6	-1.5	-1.2	-1.4	-1.1
Headache pain in last month	1.3	2.3	6.5	-1.6	-1.4	-1.8	-1.4	-0.1	-1.0	-1.4	-1.6	-1.5	-1.6	-1.4	-0.8	-1.5	-2.6	-1.5	-1.7	-1.4
Leg fat mass (right)	1.3	5.1	10.1	-2.0	-2.0	-1.9	-2.2	-3.2	-2.3	-1.9	-2.6	-2.0	-2.1	-2.1	-2.6	-2.0	-2.3	-2.1	-2.0	-2.6
Alcohol drinker status: Previous	1.3	1.5	2.5	-1.2	-1.1	-1.5	-0.9	-1.4	-1.2	-1.5	-0.8	-1.1	-1.0	-1.1	-1.6	-1.5	-1.3	-1.2	-1.1	-1.2
Leg fat mass (left)	1.3	5.2	9.6	-2.0	-2.1	-2.0	-2.3	-3.1	-2.3	-2.0	-2.6	-2.1	-2.1	-2.1	-2.6	-2.0	-2.3	-2.2	-2.0	-2.6
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	5.3	-1.3	-1.4	-0.8	2.3	-0.4	-1.3	-1.1	-1.3	-1.5	-0.8	-1.1	-1.2	-1.4	-1.5	-1.0	-1.2	-0.8
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.2	-1.4	-1.3	-1.3	-0.7	-0.5	-0.8	-1.3	-1.5	-1.2	-1.3	-1.2	-1.2	-1.4	-1.0	-1.3	-1.3	-1.3
Qualifications: nursing, teaching	1.2	1.9	4.5	-1.3	-1.4	-1.6	1.7	-0.5	-1.8	-1.4	-1.3	-1.4	-1.2	-1.0	-1.5	-1.5	-2.1	-1.1	-1.4	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	5.0	0.9	0.7	1.7	2.2	0.2	1.0	1.1	1.3	0.6	1.2	0.7	2.2	1.2	0.1	0.9	0.6	1.0
Basal cell carcinoma (self-reported)	1.2	1.4	2.7	-1.1	-1.0	-1.3	-0.3	1.6	-1.5	-1.5	-1.4	-1.2	-1.4	-1.0	0.6	-1.2	-0.9	-1.1	-1.0	-1.0
Relative age of first facial hair	1.1	2.3	4.3	-1.8	-1.4	-1.2	0.1	-0.7	-2.1	-1.6	-1.9	-1.8	-1.7	-1.8	-0.6	-1.5	-1.3	-1.7	-1.8	-1.5
Multivitamins +/- minerals	1.1	1.4	3.5	-1.2	-1.0	-1.3	-1.9	-1.2	-0.9	-1.3	-1.3	-0.8	-1.0	-1.1	-1.0	-1.4	-0.3	-1.2	-1.0	-1.3
Medication: Atenolol	1.1	1.3	5.4	1.2	1.1	1.0	2.3	-0.4	0.6	1.1	1.7	0.8	1.5	1.1	0.8	0.8	0.4	1.2	0.9	1.2
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	4.1	-1.4	-1.0	-1.2	-1.5	-1.0	-0.4	-1.4	-1.6	-1.4	-1.7	-1.3	0.3	-1.5	-2.0	-1.4	-1.5	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.8	5.5	-1.4	-1.2	-1.6	-2.3	-0.3	-0.3	-1.3	-1.5	-1.0	-1.5	-1.3	0.5	-1.4	-0.9	-1.5	-1.3	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.2	1.1	1.2	0.9	0.9	0.9	1.2	1.1	1.5	1.1	1.2	1.2	0.9	1.0	0.9	1.2	1.1	1.3
Whole body fat-free mass	1.1	6.1	12.1	-2.2	-2.4	-2.4	-2.6	-1.9	-2.6	-2.5	-3.3	-2.1	-2.5	-2.4	-3.5	-2.3	-1.1	-2.5	-2.1	-2.7
Whole body water mass	1.1	6.2	11.6	-2.3	-2.4	-2.4	-2.7	-1.9	-2.7	-2.5	-3.4	-2.1	-2.6	-2.4	-3.3	-2.3	-1.1	-2.5	-2.1	-2.7
Wears glasses or contact lenses	1.1	1.2	2.0	1.3	0.9	0.8	1.1	0.2	1.0	1.2	1.3	1.2	1.1	1.2	1.4	1.4	1.0	1.1	1.3	0.9
Illnesses of father: High blood pressure	1.1	1.3	3.4	-1.2	-1.2	-1.7	0.9	-0.9	-0.9	-1.6	-0.8	-1.2	-1.1	-1.1	-0.5	-1.8	-0.9	-1.1	-1.2	-0.6
Ever smoked	1.1	2.0	5.1	1.2	1.4	1.5	-0.6	1.8	1.9	1.2	1.2	1.3	1.2	1.2	2.3	1.3	1.6	1.2	1.3	1.0
Irritable Bowel Disease (IBD)	1.0	2.3	4.1	1.6	1.3	1.9	0.6	-1.1	1.3	1.8	2.0	1.6	1.7	1.3	0.2	1.8	2.0	1.5	1.5	1.3
Allergy or Eczema	1.0	2.6	7.4	-1.7	-1.8	-1.4	1.0	-0.5	-1.4	-1.6	-1.3	-2.1	-1.3	-1.7	-1.3	-1.3	-2.7	-1.6	-2.0	-1.4
Ever had hysterectomy (womb removed)	1.0	1.1	3.5	-1.0	-1.1	-0.6	-0.4	-1.2	-1.4	-1.0	-1.3	-1.0	-1.2	-1.0	-1.9	-0.6	-0.7	-1.1	-1.0	-1.0
Body mass index (BMI)	1.0	4.2	5.9	-1.9	-1.9	-1.9	-2.4	-2.4	-1.6	-1.8	-2.2	-1.9	-1.9	-2.0	-2.3	-1.9	-2.1	-2.0	-1.9	-2.4
Had menopause	1.0	1.3	2.6	-1.1	-1.1	-0.9	-1.2	-1.1	-1.6	-1.0	-0.8	-0.8	-1.0	-1.0	-1.6	-0.8	-1.2	-1.2	-1.1	-1.3
Worrier / anxious feelings	1.0	1.8	3.2	-1.4	-1.1	-1.6	-1.3	-1.8	-1.1	-1.4	-1.3	-1.3	-1.3	-1.3	-1.1	-1.4	-1.4	-1.3	-1.3	-1.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	7.0	-1.0	-0.8	-1.1	-1.4	-2.6	-0.2	-1.0	-0.6	-0.9	-1.1	-1.0	0.4	-1.0	-0.8	-1.0	-0.9	-1.1
High blood pressure (siblings)	1.0	1.5	3.0	1.3	1.0	1.7	1.1	1.4	1.1	1.3	0.7	1.3	1.2	1.2	0.2	1.4	1.5	1.2	1.3	1.1
Eye problems/disorders: None of the above	1.0	1.1	4.5	0.9	0.8	0.7	0.6	-1.1	0.9	1.0	0.7	0.9	1.0	0.7	2.1	0.7	1.6	1.0	0.9	1.0
Medication for pain relief, constipation, heartburn	1.0	1.6	5.5	1.3	1.0	1.1	-0.3	-1.6	0.5	1.4	1.1	1.4	1.1	1.3	-2.4	1.4	1.1	1.2	1.3	1.1
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	4.0	-1.4	-1.6	-1.7	0.1	-0.6	-1.6	-1.6	-2.0	-1.5	-1.6	-1.5	-1.3	-1.4	-1.0	-1.4	-1.4	-1.3
Osteoporosis (self-reported)	1.0	1.2	3.1	-1.0	-1.1	-0.2	0.3	-1.4	-1.8	-0.8	-0.8	-1.3	-0.9	-1.1	-1.4	-0.6	-1.7	-1.0	-1.1	-1.1
Commuting to job workplace: Public transport	1.0	1.2	2.1	-1.3	-1.4	-0.9	-0.5	-0.1	-1.0	-1.1	-1.2	-1.2	-1.3	-1.4	-0.6	-0.9	-0.9	-1.3	-1.3	-1.4
Alcohol drinker status: Never	1.0	1.2	2.2	-1.1	-1.2	-1.2	0.4	-0.5	-1.4	-1.1	-1.3	-1.0	-0.9	-1.0	-1.5	-1.3	-1.2	-1.0	-1.1	-0.9
Mean Putamen Volume	0.9	1.0	5.0	-1.0	-0.7	-0.6	-2.2	1.0	-0.2	-0.8	-0.7	-0.8	-1.0	-0.9	-1.5	-0.7	-0.8	-1.0	-0.9	-1.0
Height	0.9	17.5	41.1	-3.9	-4.0	-3.0	-1.2	-2.2	-6.4	-4.1	-5.8	-4.0	-4.6	-4.1	-6.0	-3.4	-2.7	-4.4	-3.9	-4.2
High blood pressure (mother)	0.9	1.2	2.7	-1.1	-1.3	-0.6	0.7	-0.2	-0.7	-1.0	-0.9	-1.6	-1.1	-1.4	0.7	-0.9	-1.6	-1.2	-1.4	-1.3
Trunk fat-free mass	0.9	5.2	10.2	-2.1	-2.2	-2.2	-2.3	-1.6	-2.4	-2.4	-3.2	-2.0	-2.4	-2.2	-3.1	-2.1	-0.9	-2.3	-1.9	-2.5
Standing height	0.9	9.2	22.8	-2.7	-2.8	-2.4	-0.7	-2.0	-4.8	-3.0	-4.2	-2.8	-3.2	-2.9	-4.3	-2.4	-1.9	-3.1	-2.7	-3.1
Pulse wave reflection index	0.9	1.1	4.0	-0.7	-1.1	-1.7	-1.3	-2.0	-0.2	-0.9	-0.9	-0.9	-0.8	-0.9	-1.1	-1.1	-0.9	-0.8	-0.9	-0.8
Shortness of breath walking on level ground	0.9	1.0	1.8	-1.0	-1.0	-0.5	-1.2	-0.4	-1.3	-1.2	-0.7	-1.1	-1.0	-1.1	0.4	-0.6	-1.1	-1.3	-1.1	-1.3
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.0	-1.1	-1.1	-1.4	-0.8	-1.2	0.2	-1.2	-0.9	-1.0	-1.0	-1.0	0.2	-1.4	-1.2	-1.1	-1.1	-1.2
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.0	-1.0	-1.1	-1.1	-0.6	-1.2	-0.5	-0.9	-1.4	-1.0	-1.4	-1.1	0.3	-0.9	-0.6	-1.0	-1.0	-1.1
Diastolic blood pressure, automated reading	0.9	2.7	4.2	1.8	1.5	1.6	1.4	1.9	1.5	1.8	2.0	1.7	1.8	1.7	0.8	1.8	1.2	1.6	1.6	1.6
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	1.7	-1.1	-1.0	-0.8	-1.1	-0.4	-1.2	-1.0	-1.3	-1.2	-1.1	-1.1	-0.2	-0.5	-1.3	-1.2	-1.2	-1.1
Prostate Cancer	0.8	1.1	5.1	0.9	1.4	1.0	1.8	2.2	0.1	0.3	0.3	0.4	0.7	0.8	1.4	1.0	0.1	0.7	0.8	0.6
Age at First Birth	0.8	1.1	3.0	-0.8	-1.1	-1.2	1.2	-1.7	-0.6	-0.8	-0.5	-1.1	-0.8	-0.8	-1.7	-0.9	-1.5	-0.8	-1.0	-0.6
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.4	-1.0	-1.0	-1.8	-1.3	-0.4	0.1	-1.2	-1.3	-0.9	-1.1	-0.9	0.1	-1.2	-0.8	-1.1	-0.9	-1.2
Number of live births	0.8	1.1	2.2	-0.9	-1.1	-1.4	-0.1	-1.5	-0.7	-1.3	-0.8	-1.1	-0.8	-1.0	-0.1	-1.4	-1.3	-1.0	-1.1	-0.8
Trunk predicted mass	0.8	4.9	9.6	-2.0	-2.1	-2.1	-2.3	-1.5	-2.3	-2.3	-3.1	-1.9	-2.3	-2.1	-3.1	-2.1	-0.8	-2.2	-1.8	-2.4
Exposure to tobacco smoke outside home	0.8	1.1	2.9	-1.0	-1.0	-0.9	-1.1	-0.6	-1.1	-1.2	-0.6	-0.9	-1.0	-1.1	-1.7	-1.3	-0.4	-1.1	-1.0	-0.9
Arm predicted mass (right)	0.8	3.9	9.2	-1.8	-1.9	-1.9	-1.8	-1.0	-1.8	-2.1	-2.9	-1.7	-2.0	-2.0	-3.0	-1.9	-0.8	-2.0	-1.7	-2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.1	-1.0	-1.1	-1.4	-0.9	-1.2	-0.3	-0.8	-0.9	-0.8	-0.7	-0.8	-0.9	-1.3	-1.0	-0.7	-0.9	-0.7
Average weekly beer plus cider intake	0.8	1.1	3.0	1.1	1.2	0.9	0.3	1.7	1.1	0.9	1.2	1.1	0.8	1.2	0.6	1.1	0.5	1.0	1.1	0.8
HbA1C	0.7	0.8	1.5	-1.2	-1.2	-1.1	-0.4	0.6	-0.6	-1.0	-0.6	-1.0	-1.0	-1.1	-0.5	-0.5	-1.1	-0.9	-0.9	-1.1
Respiratory disease	0.7	1.6	2.9	-1.4	-1.5	-1.3	0.6	1.1	-0.5	-1.4	-1.3	-1.7	-1.0	-1.5	-0.4	-1.2	-1.6	-1.3	-1.5	-1.0
Medication: Co-codamol	0.7	0.8	1.3	-1.0	-0.8	-1.0	-0.0	0.6	-1.2	-1.1	-1.0	-1.0	-1.0	-1.0	-0.5	-0.6	-0.7	-1.0	-1.0	-0.6
Medication: Metformin	0.7	1.0	2.1	-1.0	-1.0	-0.6	0.2	-0.8	-0.9	-1.0	-1.4	-1.4	-0.8	-1.3	0.5	-0.8	-1.4	-1.0	-1.2	-1.1
Forced vital capacity (FVC)	0.7	2.7	6.3	-1.7	-1.7	-1.5	-0.7	-0.5	-2.2	-1.7	-1.9	-1.5	-1.9	-1.7	-2.5	-1.3	-0.6	-1.8	-1.7	-1.5
Diabetes (self-reported)	0.7	1.0	2.8	-1.0	-1.1	-0.7	-0.4	0.6	-0.1	-1.0	-1.3	-1.4	-0.8	-1.3	0.1	-0.9	-1.7	-1.1	-1.3	-1.2
Supplements: Vitamin C	0.7	0.8	1.5	-1.0	-1.1	-1.2	-1.2	0.2	-0.2	-1.0	-0.9	-1.1	-1.1	-1.1	-0.4	-0.6	-0.8	-1.0	-1.0	-0.7
Mineral and other dietary supplements	0.7	0.9	1.7	1.1	1.3	1.2	1.0	0.1	0.3	1.1	1.1	1.0	1.0	1.1	0.7	0.9	0.7	1.1	1.1	0.9
Supplements: Calcium	0.7	0.8	5.5	0.7	0.2	1.1	2.4	0.1	0.5	1.0	0.6	0.3	0.6	0.5	0.4	1.1	0.4	0.8	0.5	1.0
Fasting Glucose	0.6	0.8	1.7	-0.8	-0.9	-1.2	-0.8	0.1	-0.2	-0.9	-0.8	-0.9	-0.7	-0.8	0.5	-0.8	-1.3	-1.1	-1.2	-1.0
Neuroticism (2016)	0.6	0.8	1.8	-0.9	-0.9	-1.3	-1.3	-0.5	0.2	-0.9	-0.6	-0.6	-0.4	-0.8	1.1	-1.3	-0.9	-0.8	-0.9	-1.0
Schizophrenia (2014)	0.6	1.2	2.2	1.1	1.4	0.5	1.1	0.7	1.5	1.2	1.1	1.1	1.1	1.3	-0.5	1.1	0.6	1.3	1.2	1.2
Diabetes (father)	0.6	0.7	5.0	-0.6	-0.9	-0.9	2.2	0.3	-0.4	-0.4	-1.1	-0.9	-0.3	-0.6	-0.2	-0.8	-1.1	-0.2	-0.8	0.1
High blood pressure	0.6	1.7	3.2	-1.1	-1.3	-1.5	0.1	-1.7	-1.3	-1.5	-0.8	-1.2	-1.0	-1.0	-1.5	-1.8	-1.7	-1.2	-1.1	-1.2
Chronic bronchitis/emphysema (father)	0.6	0.7	2.2	0.7	0.4	0.5	-0.4	0.9	1.5	0.9	0.5	0.8	1.0	0.7	1.4	0.8	0.8	0.8	0.8	0.6
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	4.7	-1.4	-1.4	-1.5	-0.8	-0.8	-2.1	-1.5	-1.4	-1.2	-1.8	-1.4	-2.2	-1.2	-0.6	-1.5	-1.3	-1.3
Medication: Cholesterol lowering	0.6	1.0	5.0	0.8	0.7	0.4	2.2	-0.4	0.3	0.7	1.2	0.6	1.1	0.7	1.8	0.4	0.6	0.9	0.7	0.8
Medication: Lansoprazole	0.6	0.6	2.2	-0.8	-1.0	-0.8	0.2	-1.2	-0.3	-0.6	-0.3	-0.7	-0.3	-0.8	-1.5	-0.8	-0.7	-0.7	-0.8	-0.8
Impedance of arm (left)	0.6	2.6	7.5	-1.6	-1.3	-0.8	1.0	-2.2	-2.7	-1.4	-1.4	-1.8	-1.5	-1.5	-0.5	-1.2	-2.5	-1.5	-1.7	-1.4
Loud music exposure frequency	0.6	0.7	1.4	-1.1	-0.9	-0.7	-0.0	-0.0	0.6	-0.6	-0.9	-1.0	-0.9	-1.1	0.2	-0.8	-0.9	-0.9	-1.2	-0.8
Leg fat percentage (right)	0.6	2.3	7.5	-1.2	-1.2	-1.2	-1.5	-2.7	-1.3	-1.1	-1.6	-1.2	-1.2	-1.2	-1.9	-1.4	-2.0	-1.3	-1.3	-1.8
Arm fat-free mass (right)	0.6	3.2	7.8	-1.5	-1.6	-1.6	-2.3	-1.0	-1.7	-1.8	-2.6	-1.4	-1.8	-1.7	-2.8	-1.6	-0.5	-1.8	-1.4	-2.0
Asthma (self-reported)	0.6	1.3	3.2	-1.2	-1.2	-1.1	0.4	1.1	-0.2	-1.2	-1.1	-1.5	-0.9	-1.3	-0.1	-1.1	-1.8	-1.1	-1.4	-0.8
Osteoarthritis (self-reported)	0.6	0.8	2.0	-1.0	-0.9	-0.8	0.6	0.6	0.3	-0.9	-1.4	-1.1	-0.9	-1.0	0.9	-0.9	-1.1	-0.8	-0.9	-0.8
Leg fat percentage (left)	0.6	2.2	6.6	-1.2	-1.2	-1.2	-1.7	-2.6	-1.2	-1.1	-1.5	-1.2	-1.3	-1.2	-1.8	-1.3	-2.0	-1.3	-1.3	-1.7
Risk taking	0.6	0.8	4.6	0.8	0.7	0.4	1.5	2.1	1.7	0.4	0.7	0.2	0.7	0.4	-0.1	0.8	0.5	0.6	0.4	0.9
Alzheimer’s Disease (in father)	0.5	0.6	1.6	-0.6	-0.5	-1.2	0.0	-0.4	-0.3	-1.0	-1.2	-0.6	-1.0	-0.7	1.0	-0.7	0.4	-0.8	-0.5	-0.9
Reaction Time	0.5	1.0	4.4	-0.9	-1.2	-0.9	-2.1	0.4	0.1	-1.1	-0.1	-0.8	-0.9	-0.8	-0.6	-1.0	-1.4	-1.1	-0.9	-1.2
Blood White Count	0.5	4.0	8.4	-2.1	-2.3	-1.9	-2.9	-2.3	-1.4	-1.8	0.7	-1.7	-2.2	-2.0	-0.9	-1.8	-1.8	-2.3	-2.0	-2.6
BMI	0.5	2.7	9.3	-1.2	-1.2	-1.3	-3.0	-2.9	-1.1	-1.1	-1.4	-1.0	-1.4	-1.2	-2.8	-1.2	-1.0	-1.3	-1.0	-1.6
Sensitivity / hurt feelings	0.5	0.9	2.0	-1.0	-0.7	-1.4	0.2	0.3	-0.5	-1.4	-0.8	-1.1	-0.9	-0.9	0.8	-1.2	-1.1	-1.0	-1.0	-0.7
Impedance of leg (left)	0.5	2.3	7.8	1.4	1.5	2.1	2.8	0.4	0.6	1.6	1.6	1.1	1.5	1.4	1.7	1.5	0.5	1.5	1.1	1.6
Number of incorrect matches in round	0.5	0.9	1.4	-1.0	-1.0	-1.0	-1.1	-0.8	-0.8	-1.2	-1.1	-0.7	-1.0	-1.0	0.2	-1.1	-0.0	-1.1	-0.9	-1.0
Pain all over the body in last month	0.5	0.5	1.4	-0.8	-0.4	-0.4	-0.6	0.8	-0.4	-0.8	-0.9	-0.6	-0.5	-0.8	-1.2	-0.7	0.0	-0.8	-0.6	-0.8
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.4	0.9	0.8	1.0	0.7	0.4	0.7	0.9	1.2	0.6	0.8	0.8	1.1	1.0	0.1	0.9	0.6	1.1
Asthma	0.5	0.9	2.5	-1.0	-1.0	-0.7	0.5	1.4	-0.1	-0.9	-0.9	-1.3	-0.8	-1.0	0.1	-0.7	-1.6	-0.9	-1.1	-0.6
Birth weight	0.5	1.0	3.3	-1.0	-0.9	-0.9	-1.5	-1.1	-0.8	-0.6	-1.5	-0.5	-1.1	-0.8	-1.8	-0.8	-0.1	-0.8	-0.7	-0.9
Age at first live birth	0.5	0.8	1.9	-0.8	-1.0	-1.0	0.1	-1.4	-1.0	-0.7	-1.0	-1.0	-0.6	-0.8	-1.2	-0.9	-1.0	-0.6	-0.9	-0.5
Emphysema/chronic bronchitis	0.5	0.5	1.3	-0.7	-0.5	-0.5	-0.5	0.6	-0.2	-0.8	-1.1	-0.8	-0.8	-0.8	-0.6	-0.7	-0.6	-0.8	-0.8	-0.9
Medication: Omeprazole	0.5	0.6	1.5	-0.8	-0.6	-0.4	-0.8	-0.6	-0.9	-0.5	-1.2	-1.0	-0.9	-0.8	0.3	-0.1	-1.0	-0.8	-0.8	-0.8
Ever had bowel cancer screening	0.5	0.6	2.1	-0.8	-0.9	-0.5	-0.0	0.0	-0.7	-0.4	-0.7	-1.0	-0.9	-0.8	-1.0	-0.2	-1.5	-0.7	-0.9	-0.7
Financial situation satisfaction	0.5	0.6	2.1	-0.7	-0.8	-0.6	-1.0	-1.5	-0.6	-0.7	-0.5	-0.8	-0.4	-0.8	-0.6	-0.7	-1.0	-0.7	-0.8	-0.9
Medication: Bendroflumethiazide	0.5	0.7	1.6	-0.7	-0.9	-0.9	0.5	-0.8	-1.3	-0.9	-0.7	-0.6	-0.7	-0.6	-0.9	-1.1	-1.0	-0.7	-0.7	-0.7
Arm fat-free mass (left)	0.5	2.5	6.2	-1.3	-1.4	-1.4	-2.0	-1.0	-1.6	-1.5	-2.5	-1.2	-1.6	-1.4	-2.5	-1.3	-0.4	-1.6	-1.2	-1.8
Irritability	0.5	0.9	2.4	-0.8	-0.9	-1.6	-1.2	-0.8	-1.0	-1.3	-0.7	-0.7	-0.8	-0.8	0.1	-1.3	-0.4	-0.9	-0.8	-1.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.2	-0.8	-1.0	-0.7	-0.2	-0.7	-0.6	-0.4	-0.9	-1.1	-0.8	-1.0	-0.3	-0.4	-0.9	-0.5	-0.7	-0.6
Smoking Status	0.4	0.9	8.4	-0.2	0.1	0.3	-2.2	0.9	0.1	-0.4	-0.3	-0.2	-0.5	-0.3	2.9	-0.1	0.3	-0.5	-0.2	-0.6
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	4.1	0.2	0.0	-0.0	1.6	2.0	-0.3	-0.2	0.1	-0.1	0.6	0.0	-0.4	-0.1	-0.3	0.1	-0.0	0.2
Impedance of leg (right)	0.4	2.0	8.9	1.3	1.4	1.9	3.0	0.0	0.4	1.5	1.4	1.0	1.4	1.3	1.4	1.4	0.3	1.4	1.0	1.5
Maternal smoking around birth	0.4	0.5	2.9	-0.6	-0.7	-0.5	-1.7	0.8	-0.3	-0.7	-0.9	-0.4	-0.8	-0.7	0.1	-0.4	0.2	-0.8	-0.5	-1.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	3.6	-0.6	-0.2	-0.2	-1.9	-0.3	0.4	-0.3	-0.2	-0.3	-0.6	-0.5	-0.8	-0.5	-0.4	-0.5	-0.4	-0.7
Nervous feelings	0.4	0.7	1.4	-0.9	-0.8	-1.2	-0.5	-0.8	-1.0	-1.1	-0.9	-0.7	-0.8	-0.8	0.3	-1.2	-0.7	-0.8	-0.9	-0.7
Hearing difficulty/problems with background noise	0.4	0.6	5.1	-0.6	-0.9	-0.3	-2.3	0.2	0.0	-0.3	-0.7	-0.4	-0.5	-0.7	0.1	-0.2	-0.3	-0.7	-0.6	-0.9
Impedance of arm (right)	0.4	1.8	6.5	-1.2	-1.0	-0.5	0.8	-2.5	-2.5	-0.9	-0.8	-1.4	-1.1	-1.1	-0.2	-0.7	-2.1	-1.1	-1.3	-1.1
Tense / ‘highly strung’	0.4	0.6	3.3	0.8	0.6	-0.2	1.8	1.3	0.7	0.3	0.7	0.5	0.9	0.7	0.4	0.2	0.1	0.8	0.6	0.9
Medication: Blood pressure	0.4	0.7	3.5	0.8	0.6	0.6	1.9	-0.4	-0.1	0.7	0.9	0.6	0.9	0.7	1.4	0.5	0.2	0.8	0.6	0.8
Medication: Allopurinol	0.4	0.6	0.9	1.0	0.9	0.6	0.7	0.6	0.7	0.9	0.7	0.8	0.7	1.0	-0.2	1.0	-0.0	0.9	0.8	0.8
Average weekly red wine intake	0.4	0.6	2.2	0.6	0.3	0.4	1.5	1.1	0.8	0.8	0.5	0.5	0.7	0.6	-1.1	0.5	0.6	0.7	0.5	1.0
Eye problems/disorders: Cataract	0.4	0.5	2.2	-0.5	-0.4	-0.3	-0.4	0.8	-0.6	-0.7	-0.5	-0.7	-0.6	-0.5	-1.5	-0.1	-1.2	-0.6	-0.6	-0.6
Guilty feelings	0.4	0.6	1.2	-0.9	-0.5	-1.0	-0.6	-0.8	-0.7	-0.7	-0.6	-0.8	-0.7	-0.8	-0.1	-0.9	-1.1	-0.8	-0.8	-1.1
Medication: Atorvastatin	0.4	0.5	4.0	0.1	0.0	-0.7	1.7	-2.0	-0.8	-0.4	0.2	-0.2	0.0	-0.0	0.3	-0.3	-0.1	-0.0	-0.0	-0.1
Arm predicted mass (left)	0.4	2.3	6.0	-1.2	-1.3	-1.3	-2.0	-1.1	-1.4	-1.4	-2.2	-1.1	-1.5	-1.4	-2.4	-1.2	-0.4	-1.5	-1.1	-1.7
Schizophrenia vs Biploar Disorder	0.3	0.3	1.0	0.4	0.5	0.6	-0.4	0.6	1.0	0.6	0.9	0.3	0.5	0.5	-0.8	0.5	-0.2	0.5	0.4	0.6
Cardiovascular Disease	0.3	1.0	2.9	-0.9	-0.8	-1.4	0.6	-0.6	-0.9	-1.6	-0.5	-0.9	-0.7	-0.7	-1.0	-1.7	-1.0	-0.9	-0.7	-1.0
Tanning	0.3	3.8	7.6	2.1	1.8	1.7	0.1	-1.9	1.5	2.1	2.8	2.2	2.1	1.9	1.4	2.0	2.3	2.0	2.0	1.8
Severe depression (siblings)	0.3	0.4	2.6	0.2	-0.0	0.5	1.6	0.4	0.7	0.6	0.1	0.2	0.8	-0.0	0.7	0.5	0.6	0.4	0.1	0.6
Age when periods started (menarche)	0.3	0.7	10.6	0.1	0.1	0.3	0.4	3.3	0.2	0.2	0.0	0.2	0.0	0.2	-0.1	0.5	0.2	0.0	0.1	0.2
Qualifications: None of the above	0.3	0.7	7.3	0.1	0.0	-0.2	-1.3	-2.7	0.4	-0.1	-0.2	-0.2	-0.2	-0.1	1.4	-0.3	-0.6	-0.1	-0.1	-0.4
Mouth/teeth dental problems	0.3	0.4	3.3	0.6	0.1	0.6	1.8	-0.2	-0.2	0.3	0.3	0.2	0.3	0.4	-0.4	0.8	1.1	0.5	0.5	0.9
Mouth/teeth dental problems: Dentures	0.3	0.5	1.5	0.4	0.6	0.7	-1.2	0.8	1.0	0.8	0.8	0.8	0.7	0.6	1.2	0.4	0.3	0.5	0.5	0.2
Prospective memory result	0.3	0.4	1.0	-0.7	-0.8	-1.0	-0.1	0.1	0.3	-0.7	-0.5	-0.7	-0.8	-0.7	-0.6	-0.6	-0.8	-0.6	-0.8	-0.2
Breastfed as a baby	0.3	0.4	2.2	0.4	0.5	0.9	-0.2	1.5	0.5	0.3	0.6	0.4	0.5	0.5	-0.1	0.6	0.3	0.5	0.6	0.4
Blood clot in the leg (DVT)	0.3	0.3	0.9	-0.6	-0.5	-0.5	-0.9	-0.7	-0.0	-0.3	-0.5	-0.5	-0.6	-0.6	-0.2	-0.4	-0.9	-0.6	-0.6	-0.8
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.3	-0.5	-0.4	-0.2	-1.4	0.9	0.4	-0.4	-0.8	-0.4	-0.6	-0.5	-1.5	-0.2	-0.1	-0.5	-0.4	-0.4
Glaucoma (self-reported)	0.3	0.3	0.9	-0.5	-0.4	-0.2	0.6	-0.8	-0.5	-0.6	-0.8	-0.5	-0.6	-0.4	0.3	-0.9	-1.0	-0.5	-0.5	-0.4
Chronic bronchitis/emphysema (mother)	0.3	0.4	2.1	-0.5	-0.7	-0.2	-0.6	-0.1	0.3	-0.1	-0.7	-0.7	-0.5	-0.6	1.4	-0.2	-0.8	-0.5	-0.7	-0.5
Comparative body size at age 10	0.3	0.7	4.7	0.8	0.6	0.4	0.9	-2.2	0.6	1.0	0.0	0.7	0.3	0.8	-0.7	0.5	0.7	0.8	0.7	0.7
Number of full brothers	0.3	0.4	1.7	-0.4	-0.3	-0.3	-0.1	0.8	-0.8	-0.4	-1.1	-0.4	-0.5	-0.3	-1.3	-0.6	-0.8	-0.3	-0.4	-0.2
Qualifications: College or University degree	0.3	0.9	7.4	0.3	0.4	0.6	2.7	2.4	0.3	0.3	0.3	0.2	0.4	0.3	-0.3	0.5	0.4	0.4	0.3	0.6
Angina (self-reported)	0.3	0.4	1.3	0.8	0.7	0.6	0.5	-1.1	-0.2	0.4	1.0	0.6	0.6	0.8	0.7	0.2	-0.3	0.6	0.6	0.7
Migraine (self-reported)	0.3	0.4	2.2	-0.6	-0.4	-0.4	-0.8	1.5	-0.1	-0.3	-0.4	-0.3	-0.2	-0.4	0.5	-0.6	-0.8	-0.5	-0.5	-0.6
Heart disease (mother)	0.3	0.3	0.6	-0.7	-0.6	-0.3	0.3	0.7	-0.7	-0.7	-0.3	-0.7	-0.4	-0.6	-0.5	-0.5	-0.8	-0.7	-0.7	-0.4
Hypertension (Self-reported)	0.3	0.7	2.2	-0.6	-0.8	-0.9	0.5	-1.5	-0.7	-1.0	-0.2	-0.7	-0.5	-0.5	-1.0	-1.3	-1.2	-0.6	-0.6	-0.6
Illnesses of siblings: Diabetes	0.3	0.3	1.4	0.5	0.3	1.2	0.0	0.5	0.7	0.7	-0.0	0.4	0.3	0.3	0.1	0.9	1.0	0.4	0.5	0.2
Diabetes diagnosed by doctor	0.3	0.5	1.2	-0.7	-0.9	-0.5	-0.1	0.3	0.1	-0.6	-0.9	-1.0	-0.3	-0.9	-0.1	-0.8	-1.1	-0.6	-0.9	-0.7
Average weekly champagne plus white wine intake	0.3	0.5	1.2	0.7	0.5	0.6	-0.2	0.7	-0.1	0.4	0.7	0.7	0.6	0.7	1.1	0.6	0.7	0.7	0.7	0.9
Hearing aid user	0.3	0.4	1.1	-0.6	-0.6	-0.5	0.7	-0.3	-1.0	-0.4	-1.0	-0.6	-0.7	-0.6	-0.4	-0.4	-0.2	-0.6	-0.5	-0.6
Medication: Blood pressure	0.3	0.6	3.5	-0.6	-0.6	-0.8	0.3	-0.8	-0.4	-0.7	-0.3	-0.7	-0.5	-0.5	-1.9	-1.0	-1.2	-0.5	-0.7	-0.4
Myopia	0.3	0.4	2.5	0.2	-0.0	0.4	0.2	0.8	1.6	0.8	0.1	0.2	0.4	0.1	1.5	0.3	0.3	0.4	0.2	0.4
Vascular/heart problems diagnosed by doctor	0.3	0.7	3.3	0.4	0.7	1.1	-0.4	1.8	0.8	1.0	0.1	0.5	0.4	0.4	1.1	1.3	1.2	0.5	0.5	0.6
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.6	-0.7	-0.5	-0.7	1.2	0.9	-1.2	-0.8	-0.7	-0.8	-0.7	-0.6	-1.1	-0.7	-1.1	-0.6	-0.7	-0.4
Schizophrenia (2018)	0.2	0.5	1.7	0.5	0.6	0.2	1.1	-0.0	1.1	0.7	0.5	0.3	0.4	0.6	-1.3	0.6	-0.1	0.7	0.5	0.7
Ulcerative Colitis (UC)	0.2	0.4	3.3	0.3	0.3	0.4	-0.5	-1.8	-0.1	0.3	0.6	0.5	0.5	0.2	-1.0	0.5	0.8	0.2	0.4	0.1
Verbal and Numeric Reasoning (VNR)	0.2	0.4	3.3	-0.2	0.2	0.3	1.2	1.8	-1.1	-0.0	-0.5	-0.3	-0.0	-0.1	0.4	0.2	-0.5	-0.0	-0.2	0.1
Lupus	0.2	0.3	1.0	0.5	0.6	-0.1	1.0	0.9	0.7	0.4	0.4	0.5	0.6	0.6	0.5	0.4	0.4	0.6	0.5	0.8
Ulcerative Colitis	0.2	0.2	2.3	0.1	0.0	0.4	-0.3	-1.5	-0.4	0.0	0.4	0.2	0.2	-0.0	-0.6	0.1	0.7	-0.1	0.1	-0.1
Blood Eosinophil Count	0.2	1.9	4.8	-1.4	-1.3	-1.3	-2.2	-0.9	-0.9	-1.4	-1.1	-1.2	-1.9	-1.4	-1.1	-1.2	-0.9	-1.5	-1.3	-1.6
Lung FEV1/FVC ratio	0.2	0.8	5.9	0.1	0.1	-0.5	-1.7	-2.4	-0.9	-0.5	0.5	0.3	-0.7	0.2	-1.2	-0.2	0.2	-0.3	0.3	-0.6
Systolic blood pressure, automated reading	0.2	0.6	2.3	0.8	0.8	1.5	-0.2	0.4	0.3	1.1	1.1	0.7	0.6	0.6	0.5	1.5	0.4	0.6	0.6	0.1
Angina	0.2	0.3	1.2	0.6	0.5	0.5	0.4	-1.1	-0.2	0.2	0.9	0.4	0.4	0.6	0.7	0.1	-0.4	0.5	0.4	0.5
Alcohol usually taken with meals	0.2	0.4	1.1	-0.7	-1.0	-0.8	0.0	0.3	-0.7	-0.5	-1.0	-0.5	-0.4	-0.7	0.3	-0.8	-0.2	-0.6	-0.6	-0.5
Fluid intelligence score	0.2	0.4	4.3	0.2	0.4	0.5	0.5	2.1	-0.6	0.3	0.0	0.4	0.5	0.5	0.8	0.4	0.1	0.4	0.4	0.4
Illnesses of siblings	0.2	0.3	2.6	-0.1	-0.1	-1.0	-0.8	-1.6	0.2	-0.2	0.3	-0.1	-0.0	-0.2	-0.3	-0.5	-0.5	-0.2	-0.3	-0.2
Father’s age at death	0.2	0.2	0.6	0.4	0.2	0.3	0.2	0.8	-0.5	0.5	0.5	0.3	0.2	0.3	0.1	0.8	0.8	0.3	0.3	0.4
Depression (self-reported)	0.2	0.3	1.1	-0.5	-0.7	-0.6	-1.0	-0.3	-0.1	-0.5	-0.4	-0.4	-0.5	-0.5	0.1	-0.5	-0.4	-0.4	-0.5	-0.3
Illnesses of mother	0.2	0.2	1.7	0.1	0.3	-0.2	-0.8	-0.2	-0.0	-0.1	-0.2	0.5	0.1	0.3	-1.3	-0.2	0.8	0.2	0.4	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	2.3	-0.6	-0.7	-0.6	0.1	-0.5	-1.5	-0.8	-0.8	-0.4	-1.0	-0.6	-1.1	-0.4	0.4	-0.8	-0.5	-0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	4.2	-0.5	-0.3	-0.5	0.4	-0.0	-0.5	-0.2	-0.6	-0.3	-0.2	-0.4	-2.1	-0.6	0.1	-0.2	-0.3	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.8	-0.3	-0.3	-0.2	-0.3	-0.8	0.0	-0.4	-0.5	-0.5	-0.5	-0.5	1.3	0.0	-0.3	-0.4	-0.4	-0.6
Neck or shoulder pain in last month	0.2	0.3	1.1	-0.5	-0.6	-0.9	-1.1	-0.4	-0.1	-0.6	-0.5	-0.2	-0.5	-0.3	0.5	-0.8	-0.8	-0.5	-0.5	-0.2
Medication: Seretide 50 evohaler	0.2	0.2	0.9	-0.6	-0.5	-0.3	-0.1	0.0	0.3	-0.4	-0.7	-0.6	-0.4	-0.6	0.9	-0.5	0.1	-0.4	-0.5	-0.3
Mean time to correctly identify matches	0.2	0.4	4.2	0.1	-0.4	0.1	-2.1	0.5	0.9	-0.0	0.7	0.1	-0.1	-0.0	-0.3	0.2	-0.5	-0.2	0.0	-0.5
Number of full sisters	0.2	0.2	1.8	-0.4	-0.3	-0.1	0.4	0.2	-0.2	-0.6	-0.3	-0.4	-0.2	-0.4	-1.3	-0.6	0.1	-0.3	-0.3	-0.4
Medication: Aspirin	0.2	0.3	2.6	0.2	0.2	0.4	1.6	0.5	-0.1	0.0	0.2	-0.1	0.2	0.0	1.3	0.1	0.0	0.1	0.1	0.2
Medication: Aspirin	0.2	0.2	2.1	0.1	0.0	0.2	1.5	0.7	-0.2	-0.2	0.1	-0.2	-0.1	-0.1	1.0	-0.1	-0.0	-0.1	-0.1	0.1
Mother’s age at death	0.2	0.2	2.5	0.4	0.1	0.1	0.4	0.3	0.1	0.4	0.3	0.3	0.4	0.4	-1.6	0.3	-0.0	0.3	0.3	0.3
Cholesterol lowering medication	0.2	0.3	1.4	-0.5	-0.3	-0.3	0.2	0.3	-0.3	-0.7	-0.8	-0.4	-0.7	-0.3	-1.2	-0.9	-0.3	-0.5	-0.3	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.0	-0.3	-0.2	-0.2	-0.9	-1.0	0.1	0.0	-0.3	-0.3	-0.4	-0.3	-0.1	-0.1	-0.7	-0.3	-0.4	-0.5
Bipolar Disorder (2018)	0.1	0.2	1.2	0.1	-0.1	0.5	0.5	-0.6	-1.1	0.1	-0.5	0.0	-0.1	0.1	0.3	0.2	0.2	0.1	0.2	-0.0
Bipolar Disorder or Schizophrenia	0.1	0.3	1.5	0.5	0.4	0.2	1.2	-0.5	0.2	0.7	0.1	0.2	0.3	0.5	-0.9	0.6	0.0	0.6	0.5	0.6
Ovarian Cancer	0.1	0.2	0.6	-0.4	-0.4	-0.6	0.8	0.2	-0.5	-0.2	-0.3	-0.1	-0.3	-0.3	-0.5	-0.6	0.1	-0.2	-0.3	-0.2
Body Mass Index (BMI) (2010)	0.1	0.1	0.6	-0.1	0.0	-0.8	-0.1	-0.7	-0.3	-0.3	-0.2	-0.2	-0.2	-0.1	0.2	-0.3	-0.2	-0.1	-0.1	-0.1
LDL Cholesterol	0.1	0.2	2.7	-0.0	-0.0	-0.1	-0.6	1.6	0.6	0.0	0.0	0.2	0.0	0.0	-0.3	-0.1	0.2	-0.0	-0.0	0.2
Blood Red Count	0.1	1.1	4.8	1.0	0.6	0.5	0.7	1.7	1.1	0.9	2.2	0.9	0.9	1.1	1.1	0.7	0.0	0.9	0.9	0.6
Systolic Blood Pressure	0.1	0.4	1.1	0.7	0.7	0.8	-0.2	0.5	-0.1	0.8	1.1	0.8	0.6	0.7	-0.0	0.9	0.3	0.6	0.6	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.8	-0.3	-0.6	-0.4	0.5	-0.6	0.3	-0.3	-0.4	-0.8	-0.1	-0.6	0.1	-0.5	-0.9	-0.3	-0.6	-0.2
Hearing difficulty/problems: Yes	0.1	0.1	0.6	-0.1	-0.1	0.1	-0.3	0.8	0.1	0.2	-0.6	-0.0	-0.3	-0.1	0.3	0.1	0.4	-0.2	-0.0	-0.3
Supplements: Glucosamine	0.1	0.1	0.6	0.2	0.1	-0.1	-0.8	-0.0	0.4	0.0	0.1	0.2	0.1	0.2	-0.6	0.2	0.1	0.1	0.3	-0.1
Sitting height	0.1	0.6	2.8	0.1	0.2	0.6	-0.6	-1.0	-1.7	0.3	-1.1	0.4	-0.2	0.1	-1.3	0.4	1.4	-0.1	0.3	-0.2
Medication: Simvastatin	0.1	0.1	1.4	0.0	-0.0	0.3	1.2	0.3	0.4	-0.0	0.1	-0.0	0.2	0.0	0.6	-0.4	0.0	0.1	0.0	0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.7	0.0	0.0	0.2	0.9	0.3	-0.3	0.2	0.1	0.0	0.4	0.2	-0.3	0.1	-0.3	0.1	0.1	0.1
Exposure to tobacco smoke at home	0.1	0.1	0.8	-0.0	-0.1	-0.4	-0.7	-0.3	0.1	-0.6	-0.1	-0.0	-0.2	-0.0	0.9	-0.2	0.6	-0.1	0.1	0.0
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.4	0.0	-0.1	0.6	0.1	0.1	-0.1	0.3	0.4	0.0	0.4	0.0	0.1	0.5	-0.5	0.1	-0.1	0.0
Forced vital capacity (FVC), Best measure	0.1	0.5	2.1	-0.5	-0.7	-0.3	0.7	-0.3	-1.3	-0.6	-0.9	-0.4	-0.8	-0.7	-1.5	-0.2	0.5	-0.7	-0.6	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	0.2	-0.1	0.1	-0.4	-0.1	0.2	0.4	0.5	0.3	0.4	0.1	-0.2	0.5	0.4	0.2	0.3	-0.0
Breast cancer (self-reported)	0.1	0.1	0.6	0.0	0.0	-0.1	0.5	0.5	-0.5	-0.1	-0.8	-0.0	-0.1	-0.2	-0.3	0.1	0.4	-0.1	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.8	0.2	0.3	0.7	0.4	-0.2	0.5	0.5	0.2	0.7	0.2	0.4	0.5	0.1	1.3	0.3	0.5	0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	-0.2	-0.2	0.1	-0.2	-0.5	-0.3	-0.1	0.2	0.0	-0.3	0.0	0.1	-0.4	-0.6	-0.1	-0.1	-0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	2.0	-0.2	-0.3	-0.4	-0.4	0.4	0.4	-0.3	0.1	-0.1	-0.2	-0.2	-1.4	0.2	-0.0	-0.3	-0.2	-0.0
High cholesterol (Self-reported)	0.1	0.2	0.9	-0.4	-0.3	-0.6	0.2	-0.4	-0.1	-0.7	0.2	-0.3	0.0	-0.2	0.4	-0.9	-0.2	-0.3	-0.2	-0.3
Impedance of whole body	0.1	0.6	3.8	-0.3	-0.1	0.4	1.9	-1.2	-1.4	-0.1	0.1	-0.5	-0.1	-0.2	0.5	-0.0	-1.4	-0.2	-0.5	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lung FVC	0.0	0.2	1.2	-0.0	0.1	0.9	-0.7	0.7	-0.0	0.4	0.2	0.3	-0.2	-0.1	-0.4	0.6	1.1	-0.0	0.2	0.0
Hair Pigment	0.0	0.4	3.6	0.1	0.3	0.5	1.9	1.1	0.0	0.2	0.1	0.3	0.3	0.5	0.4	0.1	0.3	0.4	0.4	0.7
Relative age voice broke	0.0	0.1	0.6	-0.1	0.0	0.2	0.2	0.8	-0.4	-0.0	-0.3	-0.0	0.0	-0.0	0.0	0.0	0.3	-0.1	-0.0	-0.0
Mouth/teeth dental problems: Bleeding gums	0.0	0.1	0.2	-0.0	0.2	-0.3	-0.5	0.1	0.0	-0.2	0.5	0.1	-0.1	-0.0	-0.3	-0.1	0.1	-0.1	0.1	-0.3
Commuting to job workplace: Cycle	0.0	0.1	0.2	-0.0	-0.1	-0.2	0.2	-0.5	0.5	0.2	0.2	-0.1	0.3	-0.1	-0.2	-0.1	-0.2	0.2	-0.1	0.3

Hub : Genes

TOMM22

Models

Trait associations