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chr7:22,449,883-24,434,409

Best TWAS P=6.4e-44 · Best GWAS P=3.89e-50 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Esophageal Carcinoma	TRA2A	0.18	0.02	blup	40	0.05	1.2e-02	-13.23	-13.9	6.4e-44	0.64	0.01	0.48	TRUE
5	GTEx	Esophagus Mucosa	CCDC126	0.12	0.03	lasso	7	0.01	4.3e-02	-10.73	10.8	4.4e-27	-0.66	0.07	0.68	TRUE
13	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS2P32	0.08	0.02	blup	27	0.02	3.1e-02	-7.34	9.0	1.7e-19	-0.70	0.02	0.43	TRUE
3	GTEx	Cells EBV-transformed lymphocytes	CCDC126	0.52	0.39	enet	26	0.40	3.0e-14	-7.98	-7.2	6.4e-13	0.30	1.00	0.00	TRUE
1	GTEx	Artery Aorta	KLHL7	0.18	0.10	lasso	6	0.07	7.3e-05	2.47	6.9	4.1e-12	-0.21	0.27	0.14	TRUE
6	GTEx	Muscle Skeletal	AK3P3	0.05	0.00	enet	14	0.00	9.9e-02	5.90	5.8	6.4e-09	-0.15	0.11	0.07	TRUE
7	GTEx	Nerve Tibial	FAM221A	0.13	0.06	enet	24	0.08	3.2e-06	4.22	-5.7	1.0e-08	0.31	0.84	0.01	TRUE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GPNMB	0.03	0.02	enet	25	0.02	1.4e-03	-1.66	5.2	2.0e-07	-0.14	0.06	0.18	TRUE
8	GTEx	Prostate	NUPL2	0.21	0.12	enet	15	0.17	4.7e-05	-0.77	-7.0	2.4e-12	0.25	0.10	0.06	FALSE
9	YFS	Blood	CCDC126	0.05	0.04	enet	10	0.05	1.6e-15	-7.96	-6.9	6.4e-12	0.42	1.00	0.00	FALSE
10	YFS	Blood	TRA2A	0.07	0.04	lasso	9	0.05	3.9e-16	-11.67	6.6	5.5e-11	-0.28	1.00	0.00	FALSE
2	GTEx	Brain Hippocampus	FAM221A	0.40	0.37	enet	24	0.38	6.0e-10	4.26	5.5	3.0e-08	-0.35	0.83	0.03	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	FAM221A	0.15	0.16	lasso	4	0.13	1.6e-05	4.19	-5.2	2.4e-07	0.33	0.32	0.03	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C7orf46	0.19	0.08	blup	52	0.09	3.4e-04	-4.74	-5.2	2.4e-07	0.20	0.02	0.10	FALSE