Hub : Genes

FAM221A

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.0807	0.0347	3.7e-03	0.084	NA	0.065	NA	0.066	3.7e-07	NA	8.2e-06	NA	6.6e-06
2	GTEx	Brain Caudate basal ganglia	0.2710	0.0810	1.2e-04	0.263	NA	0.187	NA	0.224	3.4e-08	NA	4.6e-06	NA	4.5e-07
3	GTEx	Brain Hippocampus	0.3958	0.0965	1.8e-05	0.366	NA	0.382	NA	0.367	1.7e-09	NA	6.0e-10	NA	1.6e-09
4	GTEx	Brain Putamen basal ganglia	0.2560	0.0820	6.4e-04	0.332	NA	0.260	NA	0.318	1.1e-08	NA	7.0e-07	NA	2.6e-08
5	GTEx	Breast Mammary Tissue	0.1330	0.0540	2.8e-03	0.081	NA	0.039	NA	0.048	6.1e-05	NA	4.2e-03	NA	1.7e-03
6	GTEx	Breast Mammary Tissue (Male)	0.0467	0.0782	3.2e-01	0.165	NA	0.060	NA	0.133	1.2e-04	NA	1.7e-02	NA	5.6e-04
7	GTEx	Breast Mammary Tissue (Female)	0.0185	0.0445	3.7e-01	-0.005	NA	-0.009	NA	-0.001	5.0e-01	NA	7.1e-01	NA	3.5e-01
8	GTEx	Colon Transverse	0.1100	0.0470	6.6e-03	0.049	NA	0.057	NA	0.047	2.3e-03	NA	1.0e-03	NA	2.8e-03
9	GTEx	Esophagus Gastroesophageal Junction	0.1520	0.0690	9.8e-03	0.155	NA	0.121	NA	0.133	3.1e-06	NA	4.0e-05	NA	1.6e-05
10	GTEx	Esophagus Mucosa	0.1570	0.0490	2.1e-05	0.122	NA	0.125	NA	0.124	1.5e-08	NA	1.0e-08	NA	1.2e-08
11	GTEx	Esophagus Muscularis	0.1050	0.0470	8.2e-03	-0.003	NA	-0.003	NA	-0.002	6.1e-01	NA	5.2e-01	NA	5.0e-01
12	GTEx	Muscle Skeletal	0.1142	0.0334	5.7e-07	0.127	NA	0.093	NA	0.096	1.9e-12	NA	2.2e-09	NA	1.2e-09
13	GTEx	Nerve Tibial	0.1323	0.0430	4.4e-05	0.057	NA	0.079	NA	0.027	7.1e-05	NA	3.2e-06	NA	4.9e-03
14	GTEx	Pancreas	0.3090	0.0870	8.4e-06	0.256	NA	0.193	NA	0.226	3.1e-11	NA	1.4e-08	NA	6.1e-10
15	GTEx	Pituitary	0.3390	0.0930	8.8e-05	0.275	NA	0.178	NA	-0.008	1.3e-07	NA	3.1e-05	NA	5.6e-01
16	GTEx	Skin Not Sun Exposed Suprapubic	0.1080	0.0470	4.9e-03	0.067	NA	0.039	NA	0.043	1.5e-04	NA	3.2e-03	NA	2.1e-03
17	GTEx	Skin Sun Exposed Lower leg	0.1100	0.0390	2.2e-04	0.119	NA	0.103	NA	0.115	4.3e-10	NA	7.4e-09	NA	8.6e-10
18	GTEx	Testis	0.4500	0.0650	4.4e-16	0.353	NA	0.422	NA	0.418	1.8e-16	NA	2.8e-20	NA	4.8e-20
19	GTEx	Thyroid	0.1800	0.0460	5.3e-08	0.174	NA	0.113	NA	0.150	2.5e-13	NA	6.0e-09	NA	1.5e-11
20	METSIM	Adipose	0.0422	0.0190	4.8e-03	0.017	0.023	0.028	0.023	0.025	1.1e-03	2.1e-04	3.7e-05	1.9e-04	9.7e-05
21	ROSMAP	Brain Pre-frontal Cortex	0.2860	0.0414	0.0e+00	0.364	0.341	0.377	0.378	0.377	4.1e-49	2.7e-45	3.3e-51	2.6e-51	3.9e-51

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21
Bipolar Disorder (2018)	1.0	1.6	3.6	-0.9	1.5	1.5	1.5	-0.9	-1.0	0.6	-1.3	-1.6	-1.3	-1.0	-1.4	-1.9	-1.6	-1.4	-0.3	-1.0	-1.1	-1.1	-0.3	1.5
Bipolar Disorder or Schizophrenia	3.7	9.1	16.5	-3.2	3.2	2.8	3.2	-2.8	-2.2	0.3	-2.6	-3.2	-2.8	-3.2	-2.9	-3.7	-3.6	-4.1	-1.4	-3.9	-3.1	-3.5	-2.1	3.2
Depressed Affect (Nagel 2018)	0.2	0.5	1.5	-1.0	0.5	0.4	0.6	0.6	-0.2	0.3	-0.4	-0.5	-0.5	-0.3	-0.5	-0.6	-0.6	-0.8	-0.9	-0.9	-0.9	-1.2	-1.0	0.8
Depression (Nagel 2018)	1.8	2.7	10.2	1.4	-1.4	-1.8	-1.3	3.2	2.1	0.6	1.8	1.4	1.9	2.0	1.6	2.0	1.4	1.8	0.5	1.5	1.7	1.3	0.8	-1.0
Intelligence (Savage-Jansen 2018)	0.6	1.7	5.3	-0.6	1.3	1.4	1.2	-1.1	-1.0	1.4	-2.3	-1.1	-1.7	-0.7	-1.6	-1.3	-1.5	-1.0	-1.8	-1.3	-1.0	-0.4	0.5	1.8
Neuroticism (Nagel 2018)	0.6	1.4	6.3	-1.2	0.9	0.6	0.9	-0.6	-0.4	0.6	-1.3	-0.7	-1.0	-1.2	-1.0	-1.2	-1.3	-1.6	-0.4	-2.5	-1.1	-1.5	-0.5	1.5
Schizophrenia (2018)	4.1	8.6	18.1	-3.4	2.9	2.4	3.0	-2.8	-2.0	-0.2	-2.3	-2.9	-2.5	-3.3	-2.6	-3.2	-3.4	-4.1	-1.5	-4.3	-3.0	-3.6	-2.4	3.0
Schizophrenia vs Biploar Disorder	4.3	5.6	12.6	-2.7	2.4	2.5	2.5	-2.2	-1.5	-0.7	-2.1	-2.2	-2.2	-2.5	-2.3	-1.6	-2.6	-3.3	-2.1	-3.5	-2.3	-2.6	-1.8	2.7
Worry (Nagel 2018)	0.7	1.5	8.1	-1.1	0.6	0.5	0.6	-1.2	-0.8	1.1	-1.2	-0.4	-1.1	-1.8	-0.8	-1.5	-1.1	-1.7	0.3	-2.8	-1.1	-1.4	-0.6	1.1
Alzheimer’s Disease (in mother)	0.9	1.0	4.4	-1.1	-0.0	0.5	0.3	-2.1	-0.9	-1.6	-1.0	-0.1	-0.2	-1.1	-0.2	0.1	-0.3	-1.1	1.1	-1.5	-0.8	-1.6	-1.0	0.5
Alzheimer’s Disease (in father)	0.2	0.2	1.2	-0.1	-0.6	-0.1	-0.5	0.5	0.1	-1.1	0.1	0.3	0.5	0.1	0.3	0.4	0.6	0.5	-0.8	0.1	-0.1	0.3	-0.2	-0.8
Alzheimer’s Disease (including proxy)	0.3	0.4	3.1	-0.4	-0.6	0.1	-0.2	-0.7	-0.3	-1.8	-0.8	0.4	0.5	-0.2	0.2	1.2	0.2	-0.0	-0.2	-0.8	0.1	-0.5	-0.3	0.0
Crohns Disease (2017)	0.2	0.4	1.4	-0.5	0.5	1.0	0.4	-0.3	1.0	-0.7	0.4	-1.0	0.2	0.5	-0.0	0.0	-0.6	-0.7	-1.2	-0.5	-0.6	-0.6	0.2	0.6
Irritable Bowel Disease (IBD)	0.1	0.2	0.9	-0.4	0.0	0.5	0.1	-0.7	0.3	-1.0	-0.0	-0.4	0.4	0.0	0.0	0.5	-0.2	-0.5	-0.6	-0.5	-0.8	-0.5	0.1	0.2
Ulcerative Colitis (UC)	0.1	0.2	0.8	-0.3	0.2	0.2	0.3	-0.8	-0.2	-0.8	-0.5	-0.3	0.1	-0.3	-0.3	0.2	-0.2	-0.3	-0.1	-0.4	-0.9	-0.5	-0.0	0.1
Major Depression (MDD)	1.0	1.2	6.1	-1.0	-0.7	-0.8	-0.6	-1.9	0.1	-2.3	-0.3	0.8	0.6	-0.8	0.5	-0.9	0.1	-1.5	0.2	-2.5	-0.2	-1.4	-0.2	0.1
Reaction Time	5.8	11.0	16.9	-3.2	3.5	3.2	3.4	-1.7	-3.5	1.5	-3.4	-3.7	-3.6	-4.1	-3.7	-3.1	-3.6	-3.3	-2.4	-3.4	-3.9	-2.9	-3.7	3.4
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.3	0.3	1.0	1.4	1.0	0.0	-0.4	1.1	-1.5	-0.9	-1.1	0.3	-1.2	-0.6	-0.7	-0.5	-1.0	0.4	-0.2	0.4	0.9	1.1
Breast Cancer	0.7	1.8	4.7	1.6	-0.9	-1.5	-1.0	1.5	2.2	-0.6	2.0	0.9	1.6	1.8	1.4	0.2	1.0	1.2	0.2	1.1	1.5	1.4	1.6	-0.9
Ovarian Cancer	1.7	2.3	9.1	1.5	-0.8	-0.7	-0.6	1.0	3.0	-1.2	1.5	0.8	1.7	2.5	1.3	1.6	0.8	1.3	-0.7	0.5	2.2	1.3	2.5	-0.4
Prostate Cancer	0.2	0.2	1.6	0.2	0.2	0.4	0.2	-1.3	-0.3	-1.0	-0.6	-0.6	-0.3	-0.1	-0.3	-1.0	-0.0	-0.3	0.1	-0.4	-0.1	-0.2	0.3	-0.3
Age at First Birth	0.2	0.2	1.4	0.1	0.1	-0.4	0.2	0.6	0.4	-1.0	-0.7	0.1	0.1	0.4	-0.4	0.6	0.1	0.3	-1.2	-0.0	0.1	0.3	0.3	0.2
Bipolar Disorder (2011)	1.0	0.9	3.7	-0.5	1.0	0.6	0.8	-1.7	-0.8	0.0	-0.6	-0.9	-0.6	-1.0	-0.9	-1.9	-1.1	-1.3	0.7	-1.2	-0.9	-1.0	-0.0	0.5
Body Mass Index (BMI) (2010)	0.1	0.1	0.9	-0.5	0.2	-0.2	0.2	-0.2	0.6	0.0	-0.2	-0.2	-0.1	-0.1	-0.2	-0.5	-0.3	-0.2	-0.4	-1.0	0.2	-0.3	0.1	0.5
Coronary Artery Disease (CAD)	0.2	0.2	1.1	0.3	-0.2	-0.7	-0.1	0.3	1.1	0.0	0.7	0.1	0.5	0.9	0.4	0.4	0.3	0.4	-0.3	0.2	0.7	0.2	0.8	-0.1
Crohns Disease (2012)	0.1	0.1	0.9	0.0	0.0	0.6	0.0	-0.0	0.6	0.0	-0.1	-0.4	0.2	0.5	0.0	0.7	-0.2	-0.2	-1.0	-0.2	-0.1	0.1	0.0	0.2
Mean Putamen Volume	0.2	0.2	1.3	0.7	-0.2	0.2	-0.2	-1.1	0.1	-0.6	0.1	-0.0	0.0	0.6	0.1	0.3	0.2	0.5	0.3	0.4	0.2	0.4	0.6	-0.4
Fasting Glucose	1.3	1.6	2.8	1.3	-1.5	-1.0	-1.5	1.3	1.7	0.0	1.2	1.1	1.4	1.6	1.5	1.3	1.4	1.0	0.5	0.7	1.5	1.3	1.1	-1.3
HbA1C	0.2	0.3	1.5	-0.1	0.6	0.6	0.5	-0.2	-0.2	0.0	0.2	-1.2	-0.5	-0.5	-0.3	-1.0	-0.5	-0.2	0.2	-0.1	-0.6	-0.1	-0.8	0.3
HDL Cholesterol	0.4	0.6	1.4	-1.1	0.8	1.0	0.7	-0.2	-0.3	0.0	-0.4	-1.0	-0.7	-0.7	-0.6	-0.9	-1.0	-1.2	-0.3	-0.8	-0.4	-1.1	-0.5	0.9
LDL Cholesterol	0.8	1.3	3.4	-1.1	0.8	1.3	0.6	-1.6	-1.8	0.0	-1.5	-0.8	-1.1	-1.7	-1.2	-0.9	-0.9	-0.9	-0.1	-1.1	-1.3	-1.0	-1.3	0.5
Lupus	0.3	0.5	3.0	0.6	-0.5	-0.8	-0.3	-0.9	-0.7	-1.7	0.1	0.5	-0.2	-0.3	0.2	-0.3	0.5	0.5	1.5	0.1	-0.4	0.4	-0.0	-1.0
Neuroticism (2016)	1.6	2.3	6.4	-1.2	1.6	1.3	1.4	-1.2	-1.2	0.0	-1.3	-1.3	-1.4	-1.9	-1.6	-1.6	-1.9	-2.2	-0.6	-2.5	-1.4	-1.4	-1.3	1.9
Primary Biliary Cirrhosis	0.1	0.2	0.7	0.4	0.3	0.6	0.4	0.1	0.1	0.0	-0.4	-0.6	0.0	0.1	-0.3	0.8	-0.2	-0.4	-0.8	-0.2	0.0	0.2	0.2	0.5
Rheumatoid Arthritis	0.2	0.2	1.3	0.6	0.0	0.4	0.3	-0.8	-0.8	-0.4	-0.7	-0.1	-0.3	-0.6	-0.3	-0.4	0.0	0.4	1.1	-0.1	-0.4	0.3	-0.4	-0.0
Schizophrenia (2014)	5.1	11.2	22.8	-4.2	3.2	2.7	3.3	-3.0	-2.3	-0.3	-2.5	-3.3	-2.8	-3.7	-2.8	-3.9	-3.7	-4.8	-1.7	-4.6	-3.7	-4.4	-2.9	3.4
Triglycerides	0.5	0.8	1.8	0.6	-1.1	-1.3	-1.1	-0.3	0.9	0.0	0.9	1.2	1.1	0.7	1.2	0.7	1.0	0.8	0.8	-0.0	0.6	0.3	0.9	-1.0
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.6	0.6	-1.0	-1.4	-0.8	-0.5	0.0	0.0	0.3	1.4	0.5	0.6	0.7	0.6	1.1	1.0	1.6	0.7	0.6	0.5	0.4	-1.1
Ulcerative Colitis	0.1	0.1	0.7	0.4	-0.2	-0.4	-0.3	-0.4	-0.0	-0.8	0.1	0.1	0.4	0.0	0.1	0.9	0.4	0.3	0.2	0.1	-0.1	0.4	0.2	-0.6
Blood Eosinophil Count	0.2	1.7	5.8	0.5	-1.4	-1.9	-1.5	1.3	2.4	-0.1	1.2	1.4	1.7	1.3	1.5	1.3	1.0	1.0	-0.3	-0.8	1.8	0.3	1.1	-0.6
Blood Platelet Count	0.3	3.5	8.4	1.8	-1.5	-1.1	-1.6	1.4	2.2	-0.9	1.7	1.7	1.9	2.9	1.8	2.2	1.8	2.1	0.7	2.5	2.5	1.5	2.4	-1.6
Blood Red Count	0.0	0.2	1.6	-0.2	-0.3	0.1	-0.1	-0.6	-0.8	0.2	0.4	0.4	-0.1	-0.6	0.2	-0.6	0.1	0.3	0.2	0.3	-0.5	0.0	-1.3	-0.4
Blood White Count	0.5	4.0	11.4	0.8	-2.5	-3.4	-2.4	1.6	2.3	0.5	1.5	3.2	2.7	1.7	2.3	2.6	2.0	1.5	1.0	0.1	2.5	0.7	1.2	-1.5
Heel T-Score	0.9	7.5	19.3	2.3	-3.8	-4.4	-3.3	0.9	1.7	0.1	2.4	4.2	3.1	1.4	3.4	2.7	3.3	2.5	3.2	1.1	2.2	2.1	1.7	-3.4
BMI	0.1	0.7	3.5	-0.0	-0.1	-0.2	-0.3	1.7	1.5	1.9	0.8	-0.1	0.7	1.4	0.5	1.1	0.1	0.9	-0.9	0.7	0.6	0.1	0.1	0.2
Height	1.8	34.1	73.6	-3.4	6.7	8.3	6.9	-5.5	-6.7	-2.3	-3.9	-8.1	-6.9	-6.2	-6.1	-8.6	-6.0	-4.8	-1.5	-1.7	-7.9	-3.4	-5.3	4.3
Waist Hip Ratio (WHR)	0.3	1.4	4.0	1.0	-1.2	-1.6	-1.2	1.0	0.1	1.7	0.2	1.5	1.0	0.9	0.8	2.0	1.3	1.6	0.9	1.5	1.2	1.3	0.2	-1.1
Systolic Blood Pressure	0.2	0.9	3.7	1.2	0.2	-0.5	0.3	1.5	0.9	1.0	0.8	-0.1	0.4	1.4	0.1	1.2	0.2	1.3	0.7	1.9	0.5	1.3	1.2	-0.2
Smoking Status	0.2	0.5	1.7	-1.0	0.3	-0.1	-0.1	0.4	-0.5	0.7	0.2	-0.3	-0.5	-1.2	-0.2	-0.1	-0.5	-1.0	-0.6	-1.3	-0.4	-0.8	-1.1	0.4
Allergy or Eczema	0.2	0.7	1.8	-1.0	0.3	0.3	0.1	-1.1	-1.3	-0.2	-0.5	-0.3	-0.7	-1.3	-0.4	-0.9	-0.6	-1.3	0.3	-0.9	-0.4	-1.3	-0.9	0.4
Cardiovascular Disease	0.1	0.5	1.4	-0.8	0.7	0.4	0.7	-0.5	-0.8	-0.3	-0.0	-0.9	-0.8	-0.6	-0.5	-0.9	-0.8	-0.1	-0.1	-0.2	-1.1	-0.8	-1.2	0.6
Hypothyroidism (self reported)	0.3	0.7	2.6	-0.0	0.8	1.6	0.9	-1.0	-1.6	-0.1	-0.6	-0.9	-1.2	-1.3	-0.9	-0.6	-0.6	0.2	-0.1	0.1	-0.9	0.1	-1.0	0.4
Respiratory disease	0.3	0.6	2.6	-1.2	0.4	-0.2	0.3	0.0	0.5	-1.4	0.1	-0.5	0.2	-0.3	-0.1	-0.4	-0.5	-0.9	-1.0	-1.4	-0.4	-1.6	-0.7	0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.4	-0.3	-0.0	-0.2	-0.0	0.7	1.2	-0.2	-0.2	-0.1	0.6	0.8	0.1	0.9	-0.0	-0.3	-0.4	-0.6	0.7	-0.6	0.9	0.4
Lung FEV1/FVC ratio	0.5	2.3	8.0	1.5	-1.3	-1.3	-1.5	2.1	0.6	-0.1	1.7	1.3	1.5	1.4	1.3	1.8	1.6	1.6	0.8	2.8	1.5	1.7	0.4	-1.6
Lung FVC	0.2	1.0	4.8	1.2	0.7	2.2	0.5	-1.6	-0.7	-1.8	-0.3	-1.1	-1.0	-0.6	-0.6	-0.4	-0.3	-0.4	0.7	0.0	-0.1	0.9	1.7	-0.4
Neuroticism	0.4	0.9	5.2	-1.2	0.4	-0.0	0.5	-0.0	-0.2	-0.1	-0.8	-0.3	-0.6	-1.1	-0.5	-0.9	-0.8	-1.6	-0.8	-2.3	-0.7	-1.4	-0.7	1.1
Chronotype (morning person)	0.6	1.3	3.0	1.0	-1.6	-0.8	-1.7	0.6	1.3	0.7	1.2	1.3	1.7	1.0	1.6	0.8	1.0	1.1	1.0	0.3	1.5	0.7	1.2	-0.8
Hair Pigment	0.0	0.1	0.4	0.0	0.1	0.2	0.1	0.5	0.5	0.0	0.2	-0.1	0.1	0.1	0.0	0.7	-0.2	-0.3	-0.6	-0.4	0.0	0.0	0.3	0.2
Tanning	0.3	3.4	6.5	2.1	-2.0	-1.1	-2.3	0.6	1.3	-0.8	1.9	1.7	1.8	1.7	2.0	1.8	2.3	2.2	1.7	2.0	1.8	2.0	1.5	-2.5
Hand grip strength (left)	0.1	0.4	1.2	0.7	-0.4	-0.9	-0.6	-1.0	-0.9	0.1	0.1	0.5	-0.0	-0.9	0.1	-0.2	0.4	0.2	1.1	-0.0	-0.1	0.8	-0.1	-1.0
Number of treatments/medications taken	1.0	1.9	5.8	-2.2	1.2	1.0	1.2	-0.9	-0.6	-0.8	-1.0	-1.1	-1.0	-1.0	-1.0	-0.3	-1.3	-1.4	-1.8	-1.5	-1.3	-2.4	-2.1	1.5
Average weekly spirits intake	0.1	0.2	1.0	-0.6	0.1	0.7	0.2	0.1	0.4	-0.4	0.2	-0.3	0.1	-0.2	0.0	-0.1	-0.1	-0.6	-1.0	-0.8	-0.4	-0.4	-0.5	0.2
Sensitivity / hurt feelings	0.7	1.2	3.3	-1.3	0.9	0.8	0.9	-1.5	-0.8	-0.9	-1.1	-1.0	-1.1	-1.3	-0.9	-0.7	-1.1	-1.2	-0.3	-1.8	-1.0	-1.5	-0.3	1.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.8	0.5	-0.3	-0.7	-0.2	0.9	0.4	0.2	0.3	0.4	0.7	0.7	0.3	0.9	0.4	0.8	0.3	0.7	0.4	0.2	0.0	-0.3
Hearing difficulty/problems: Yes	1.0	1.5	5.8	-1.1	1.0	0.1	1.0	-0.9	-0.4	0.1	-1.6	-0.8	-0.9	-1.1	-1.2	-1.8	-1.3	-1.5	-1.4	-2.4	-0.9	-1.3	-1.0	1.4
Relative age of first facial hair	0.4	0.8	2.3	1.1	-0.6	-1.1	-0.7	0.7	0.8	-0.4	0.5	0.7	1.0	1.1	0.6	0.5	0.8	1.5	0.2	1.3	1.0	1.1	0.9	-0.5
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	5.3	-1.5	0.8	0.4	0.8	-0.8	-1.7	1.3	-0.9	-0.6	-1.2	-1.4	-1.0	-1.1	-0.9	-1.1	-0.0	-0.5	-1.3	-1.4	-2.3	0.7
Ever used hormone-replacement therapy (HRT)	0.4	0.5	6.6	-0.3	0.1	-0.8	-0.2	1.2	0.3	2.6	0.6	0.1	0.1	-0.2	0.1	-0.1	-0.5	-0.3	-0.5	-0.3	-0.3	-0.2	-0.7	0.2
Ever had hysterectomy (womb removed)	0.6	0.7	1.7	-0.1	-0.9	-1.0	-0.9	1.1	0.1	-0.4	1.1	0.8	0.6	0.4	1.0	1.1	1.0	0.9	0.6	1.3	0.5	0.1	-0.8	-1.0
Systolic blood pressure, automated reading	0.9	2.6	6.3	1.6	-1.1	-1.6	-1.2	2.5	1.9	1.7	2.4	1.0	1.5	1.8	1.6	1.2	1.1	1.5	1.5	1.9	1.3	1.7	1.7	-1.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	1.4	0.1	-0.2	-0.4	-0.1	1.0	0.7	1.2	0.9	0.1	0.4	0.6	0.6	0.1	0.2	0.4	0.1	0.6	0.2	-0.0	-0.2	-0.0
Angina	1.6	2.1	7.7	-1.7	1.3	1.4	1.0	-1.1	0.3	0.1	-1.2	-1.5	-0.9	-0.8	-1.2	-2.0	-1.8	-1.8	-1.4	-2.8	-0.7	-1.9	-1.2	1.6
Medication for hormone replacement therapy	2.3	2.5	9.4	-1.4	1.5	1.7	1.6	-0.7	-1.7	3.1	-1.5	-1.6	-1.7	-1.6	-1.6	-1.0	-1.7	-1.3	-0.9	-1.0	-1.9	-1.3	-1.8	1.5
Vitamin and mineral supplements	0.8	1.0	6.4	0.0	-0.8	-0.7	-0.8	0.7	-1.7	1.3	0.2	1.1	-0.2	-0.8	0.4	0.4	1.0	0.3	2.5	1.6	-0.6	0.3	-0.9	-1.2
Supplements: Zinc	0.4	0.4	1.6	0.2	0.0	-0.1	0.0	1.3	1.1	-1.0	0.5	-0.2	0.3	0.9	0.2	0.4	0.2	0.7	-1.2	0.6	0.4	0.5	1.0	-0.0
Medication: Co-codamol	1.5	1.7	3.1	0.8	-1.4	-1.5	-1.5	1.8	1.5	-0.5	1.1	1.2	1.4	1.8	1.3	1.2	1.5	1.4	-0.4	1.4	1.4	1.0	1.1	-1.2
Medication: Metformin	0.2	0.3	1.1	-1.1	0.6	0.5	0.4	0.8	0.1	-0.0	-0.1	-0.9	-0.2	0.3	-0.3	-0.1	-0.4	-0.5	-1.0	0.3	-0.5	-1.0	-0.7	0.5
Diabetes (father)	0.5	0.6	2.0	-0.7	-0.9	-1.3	-0.8	1.4	0.8	0.0	0.7	0.8	0.9	0.5	1.0	1.2	0.8	-0.0	-0.2	0.1	0.1	-0.6	-0.4	-0.4
Diabetes (mother)	0.4	0.6	3.0	0.4	-0.5	-0.8	-0.7	1.4	0.5	0.5	0.2	0.9	0.5	0.7	0.3	1.7	0.5	0.5	-1.1	0.3	0.7	0.5	0.5	-0.5
Severe depression (siblings)	0.5	0.5	2.2	-0.7	-0.7	-0.9	-0.9	-0.7	0.7	-1.5	-0.0	0.5	0.7	0.1	0.6	-0.7	0.4	-0.5	0.2	-1.2	0.5	-0.9	0.8	-0.1
Pack years adult smoking proportion	0.5	0.8	3.6	-0.4	-1.2	-1.9	-1.4	-0.2	0.3	0.7	1.0	1.5	0.7	0.1	1.2	0.4	1.0	0.1	0.6	-0.2	0.8	-0.3	-0.4	-0.8
Impedance of leg (right)	0.3	1.4	5.9	-0.3	-0.8	-1.4	-0.8	-1.9	-2.4	0.3	-0.8	1.5	-0.3	-2.2	-0.0	-0.1	0.4	-0.4	1.8	-1.1	-0.5	-0.4	-1.8	-0.8
Leg fat-free mass (left)	0.4	2.0	8.6	-0.4	1.9	2.9	2.1	-0.4	-0.4	-0.7	-0.2	-2.8	-1.1	-0.4	-1.3	-1.9	-1.6	-0.6	-0.9	0.5	-1.8	-0.5	-0.5	1.2
Trunk fat percentage	0.1	0.2	1.7	-0.3	-0.1	0.1	-0.1	0.7	0.3	1.3	0.6	-0.1	0.2	0.2	0.3	0.5	-0.0	0.4	0.3	0.3	0.1	-0.3	-1.2	0.2
Hand grip strength (right)	0.4	1.1	4.7	-0.2	1.0	0.6	0.8	-2.2	-1.7	-0.7	-0.9	-1.1	-1.2	-1.6	-1.2	-1.3	-0.8	-0.7	0.1	-0.7	-1.1	-0.3	-0.8	0.1
Townsend deprivation index at recruitment	0.4	0.5	1.8	-0.7	-1.0	-1.3	-1.3	0.6	0.9	-0.8	0.3	1.0	0.9	0.4	0.9	-0.4	0.7	0.0	-0.1	-0.5	0.7	-0.6	-0.2	-0.4
Current tobacco smoking	0.3	0.5	1.6	0.3	-0.7	-0.9	-1.1	1.1	0.3	0.8	0.6	0.8	0.6	0.1	0.6	1.3	0.6	0.6	-0.2	-0.1	1.1	0.6	0.3	-0.6
Average weekly fortified wine intake	2.8	3.3	7.4	-1.4	2.2	2.3	2.2	-0.7	-1.1	0.6	-2.3	-2.0	-1.9	-1.1	-2.3	-1.2	-2.1	-1.8	-2.7	-1.3	-1.6	-1.3	-1.8	2.3
Maternal smoking around birth	2.9	4.2	7.7	2.1	-2.4	-2.2	-2.6	1.5	1.1	-0.5	2.4	2.1	2.1	1.6	2.4	2.0	2.4	1.8	2.8	1.9	2.2	1.8	1.5	-2.5
Fed-up feelings	0.2	0.3	1.0	-0.7	-0.6	-0.8	-0.3	-0.4	-0.4	-0.3	-0.3	0.8	0.1	-0.3	0.2	-0.1	0.5	-0.2	0.4	-0.6	-1.0	-0.8	-0.5	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	4.0	5.3	11.1	1.8	-2.5	-2.9	-2.6	3.3	2.3	0.4	2.4	2.5	2.7	2.5	2.6	2.5	2.4	2.4	1.5	2.2	2.0	1.5	0.8	-2.2
Relative age voice broke	1.5	2.3	4.0	1.6	-1.5	-1.9	-1.4	0.8	0.7	-0.3	0.7	1.9	1.6	1.4	1.3	1.2	1.9	2.0	2.0	2.0	1.5	1.6	1.5	-1.4
Taking other prescription medications	0.7	1.1	6.1	-1.4	0.8	0.5	0.6	-0.6	-1.4	0.5	-0.7	-0.9	-1.0	-1.1	-0.8	-0.6	-0.7	-0.7	-0.8	-0.3	-1.4	-1.3	-2.5	0.6
Age when periods started (menarche)	0.8	2.0	5.9	-1.4	1.1	1.3	0.8	-1.9	-2.4	-0.0	-2.3	-0.8	-1.5	-2.0	-1.8	-0.7	-1.0	-1.4	-0.7	-1.4	-1.3	-1.2	-1.5	0.8
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	3.4	-0.6	-0.5	-1.0	-0.5	0.8	-0.9	-0.1	0.9	0.6	-0.1	-0.8	0.6	0.1	0.4	0.3	0.6	0.7	-0.1	-0.2	-1.9	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	2.3	1.5	-1.1	-1.5	-1.2	0.9	1.1	0.9	1.0	1.3	1.1	1.0	1.1	1.0	0.8	1.0	1.3	0.5	1.3	1.0	1.1	-0.7
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.0	0.5	-1.1	-1.4	-1.1	0.6	0.6	0.9	0.8	1.4	1.1	0.7	0.9	1.1	1.0	0.9	0.6	0.7	0.6	0.5	0.8	-0.9
Qualifications: CSEs or equivalent	0.1	0.1	1.3	-0.0	0.3	0.4	0.2	0.1	-0.2	-1.1	-0.5	-0.1	-0.2	-0.0	-0.4	0.5	-0.3	-0.3	-0.6	-0.2	0.1	0.1	0.2	0.3
Serious illness, injury or assault to yourself	0.4	0.5	1.5	-0.8	0.5	0.4	0.6	-1.1	-0.4	0.7	-0.3	-0.5	-0.5	-0.6	-0.4	-0.8	-0.8	-0.7	0.5	-1.1	-0.6	-1.2	-0.4	0.5
High blood pressure	0.4	1.1	2.2	-1.2	1.3	1.0	1.4	0.6	-0.2	1.2	-0.0	-1.5	-1.1	-0.4	-0.8	-1.0	-1.4	-0.7	-0.9	-0.1	-1.4	-1.0	-1.1	1.2
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.4	-0.5	0.1	0.3	0.0	-1.2	-0.8	-1.1	-0.6	0.0	-0.5	-0.8	-0.3	-0.2	-0.2	-0.6	0.0	-0.6	-0.1	-0.8	-0.6	0.1
Multivitamins +/- minerals	0.7	0.9	3.3	-0.1	0.9	1.0	0.8	-0.7	1.5	-0.9	-0.5	-1.1	0.1	0.9	-0.6	-0.7	-1.0	-0.4	-1.8	-1.1	0.4	-0.4	1.3	1.2
Stomach or abdominal pain in last month	3.7	4.6	11.3	-3.1	2.3	1.5	2.4	-1.8	-0.9	-0.4	-1.8	-2.1	-2.2	-1.5	-1.9	-2.4	-2.6	-2.4	-1.2	-2.5	-1.6	-3.4	-1.7	2.9
Supplements: Glucosamine	0.8	1.0	3.4	-0.6	1.6	1.3	1.6	-0.3	0.1	-0.9	-0.6	-1.8	-0.7	0.1	-1.2	-0.8	-1.1	-0.8	-1.3	0.0	-0.6	-0.8	0.1	1.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.8	-0.2	-0.3	-0.3	-0.4	-0.4	-0.4	-0.9	-0.4	0.3	0.2	-0.5	0.1	0.1	0.1	-0.0	0.7	-0.6	-0.3	-0.4	-0.1	-0.2
Medication: Atenolol	1.0	1.2	2.1	-1.3	1.1	1.5	1.3	-0.9	-0.7	-0.1	-1.1	-1.4	-1.1	-0.9	-1.1	-0.1	-1.1	-1.0	-1.0	-1.3	-1.2	-1.3	-1.2	1.1
Medication: Levothyroxine sodium	2.8	4.8	7.2	-2.3	2.4	2.4	2.3	-1.9	-2.4	-0.1	-2.2	-2.2	-2.7	-2.3	-2.5	-2.2	-2.3	-2.1	-1.1	-1.7	-2.4	-2.2	-2.5	2.1
Sitting height	0.7	4.7	15.8	-0.0	2.4	3.6	2.5	-2.0	-2.3	-2.8	-1.0	-3.2	-2.1	-2.1	-2.1	-4.0	-2.1	-1.4	0.1	0.1	-3.0	-0.2	-0.7	1.0
Chronic bronchitis/emphysema (father)	0.2	0.3	0.8	0.7	0.3	0.6	0.1	0.3	0.9	0.9	0.5	-0.3	-0.0	0.7	0.2	-0.5	-0.2	0.2	0.6	0.5	0.7	0.4	0.8	0.1
High blood pressure (mother)	0.3	0.4	1.1	0.3	-0.7	-0.6	-0.7	-0.4	0.9	-1.0	0.6	0.5	1.1	0.3	0.8	0.4	0.6	0.2	-0.4	-0.8	0.6	0.0	0.2	-0.6
Body mass index (BMI)	0.1	0.6	2.0	-0.3	-0.3	-0.1	-0.2	1.3	1.4	1.3	1.0	0.0	0.7	1.3	0.7	1.1	0.3	0.7	-0.6	0.6	0.5	-0.2	-0.4	0.0
Impedance of leg (left)	0.3	1.7	7.5	-0.2	-0.9	-1.4	-0.9	-1.9	-2.7	0.3	-0.6	1.5	-0.5	-2.3	0.0	-0.2	0.4	-0.4	2.4	-0.9	-0.6	-0.3	-1.9	-0.9
Leg predicted mass (left)	0.4	2.1	8.6	-0.5	1.9	2.9	2.1	-0.5	-0.5	-0.7	-0.2	-2.8	-1.2	-0.5	-1.4	-1.9	-1.6	-0.6	-1.0	0.4	-1.9	-0.5	-0.6	1.3
Trunk fat mass	0.1	0.4	1.7	-0.4	0.6	1.0	0.8	0.4	-0.0	1.0	0.4	-1.0	-0.3	-0.0	-0.3	-0.4	-0.6	0.1	-0.1	0.4	-0.6	-0.4	-1.3	0.6
Waist circumference	0.2	0.7	3.4	-0.7	0.9	1.0	1.1	0.8	0.2	1.9	0.2	-1.2	-0.5	0.4	-0.4	-0.1	-0.8	-0.0	-0.7	0.8	-0.7	-0.6	-1.3	0.9
Number of incorrect matches in round	0.5	0.8	2.1	-1.2	0.8	0.4	1.0	-0.0	-0.7	0.5	-0.5	-0.9	-0.9	-1.3	-0.7	-0.8	-1.0	-1.1	0.1	-1.2	-1.3	-1.0	-1.4	0.7
Past tobacco smoking	0.2	0.3	1.0	0.8	-0.4	-0.4	-0.3	-0.4	0.6	-0.1	-0.0	0.3	0.6	1.0	0.3	0.3	0.5	0.8	0.6	0.7	0.5	0.5	0.9	-0.3
Alcohol usually taken with meals	0.4	0.7	1.9	-0.6	1.2	0.9	1.1	-0.5	0.5	-0.9	-0.5	-1.2	-0.6	0.1	-0.8	-1.4	-1.0	-0.9	-0.8	-0.7	-0.4	-0.8	0.6	1.2
Nervous feelings	0.4	0.7	3.7	-0.3	0.5	0.4	0.3	-1.3	-1.0	0.4	-1.4	-0.3	-0.9	-1.4	-0.9	-0.7	-0.8	-0.7	0.1	-1.9	-0.7	-0.4	-0.1	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.9	-0.3	0.5	0.1	0.5	0.9	0.4	-0.1	-0.6	-0.4	-0.2	0.2	-0.5	0.3	-0.7	0.0	-0.8	-0.5	-0.1	-0.6	-0.5	0.7
Hearing difficulty/problems with background noise	0.6	1.0	4.4	-0.3	1.0	0.2	1.1	0.2	1.3	0.4	-0.8	-0.7	-0.4	0.2	-0.7	-0.9	-1.3	-0.9	-1.7	-2.1	0.2	-0.6	0.6	1.7
Hair/balding pattern: Pattern 2	0.5	0.6	5.6	-0.3	-0.5	0.2	-0.6	-2.4	-1.4	-0.5	-1.2	0.6	-0.1	-0.7	-0.2	-0.1	0.2	-0.3	0.9	-0.5	-0.1	-0.5	-0.4	-0.3
Had menopause	0.7	0.9	7.8	0.0	-0.4	-0.9	-0.5	1.6	0.8	2.8	1.5	0.7	0.5	0.6	0.9	0.4	0.4	0.6	-0.2	0.7	0.4	0.5	-0.2	-0.3
Had other major operations	0.7	0.9	3.5	-0.1	-1.1	-1.9	-1.1	0.4	-0.8	1.1	0.7	1.5	0.2	-0.4	0.8	0.3	1.1	0.6	1.5	0.7	0.2	0.1	-1.4	-1.0
Forced vital capacity (FVC)	0.9	3.6	12.2	0.5	1.9	3.5	2.2	-2.8	-2.5	-2.2	-1.5	-2.4	-2.2	-2.1	-2.0	-2.6	-1.4	-0.9	0.2	-0.3	-2.0	0.4	0.5	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	2.7	1.6	-1.2	-1.6	-1.3	0.6	1.0	0.8	0.9	1.4	1.1	0.8	1.2	1.1	0.9	0.9	1.5	0.1	1.6	1.1	1.3	-0.8
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	3.2	-0.9	-0.4	-0.6	-0.4	-0.6	-0.0	-0.1	-0.5	0.5	0.2	-0.7	0.1	0.0	-0.1	-0.5	-0.7	-1.8	-0.2	-0.8	-0.8	0.2
Qualifications: None of the above	2.1	4.6	8.5	2.1	-2.1	-2.0	-2.2	2.9	1.3	2.3	2.5	2.1	2.1	1.7	2.1	2.7	2.2	2.4	1.1	2.7	1.9	2.4	0.5	-2.3
Financial difficulties in last 2 years	2.3	3.1	7.9	-2.0	1.0	0.8	0.8	-2.4	-2.7	0.5	-2.1	-0.7	-1.7	-2.8	-1.5	-1.6	-1.3	-1.5	-0.1	-2.4	-2.0	-2.0	-2.6	1.1
Mouth/teeth dental problems	0.4	0.7	2.3	1.2	-0.8	-0.5	-0.8	-0.6	-0.1	-0.1	0.4	0.9	0.6	0.3	0.7	0.6	0.8	0.7	1.5	0.7	1.0	0.9	1.0	-1.1
Heart attack	3.0	3.8	6.8	-2.4	1.7	1.4	1.6	-2.6	-2.0	-0.7	-2.3	-1.4	-1.7	-2.0	-2.0	-1.7	-1.7	-1.9	-1.4	-2.3	-2.1	-2.6	-2.5	1.7
Allergy	0.2	0.4	2.1	1.1	-0.1	0.0	0.0	0.7	0.7	0.7	0.1	0.0	0.2	0.9	0.1	0.5	0.2	0.9	-0.1	0.9	0.5	1.4	1.2	-0.1
Pain all over the body in last month	1.2	1.3	4.0	0.7	-1.5	-1.1	-1.3	0.8	-0.3	-0.1	0.4	1.3	1.1	0.7	1.0	0.9	1.8	1.6	1.4	2.0	0.1	0.8	-0.2	-1.8
Diabetes (self-reported)	1.0	1.5	5.5	0.7	-1.1	-1.0	-1.1	1.3	1.8	-0.6	0.9	1.0	1.6	1.9	1.2	2.3	1.2	1.0	0.3	1.0	1.6	0.5	1.3	-0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.9	-0.8	0.4	0.2	0.3	-1.4	-1.0	0.2	-0.8	-0.0	-0.6	-1.2	-0.6	-0.2	-0.4	-0.9	-0.5	-1.2	-0.7	-0.8	-0.9	0.4
Medication: Ramipril	0.1	0.1	0.6	0.0	0.3	0.1	0.3	-0.5	-0.8	0.3	-0.0	-0.2	-0.2	-0.5	-0.3	0.4	-0.3	0.2	0.3	0.0	-0.5	-0.1	-0.5	0.1
Medication: Simvastatin	0.3	0.4	1.1	-0.1	-0.5	-0.7	-0.6	0.8	1.1	0.3	0.7	0.6	1.0	0.6	0.6	1.0	0.4	0.4	-0.8	-0.2	0.5	0.1	-0.0	-0.3
Fluid intelligence score	0.1	0.3	1.2	0.8	0.0	0.6	0.0	-0.2	-0.2	1.0	-1.1	-0.0	-0.1	0.6	-0.3	0.2	0.1	0.3	0.2	0.6	0.4	0.7	1.1	0.3
Illnesses of siblings	0.8	1.1	3.4	1.7	-1.1	-0.7	-1.0	-0.4	-0.2	-0.2	0.5	1.1	0.7	0.5	0.7	0.6	1.2	1.5	1.0	1.3	0.9	1.8	1.1	-1.6
Neuroticism score	0.9	1.9	7.4	-1.7	0.9	0.8	0.9	-1.2	-1.0	-0.6	-1.4	-0.8	-1.3	-1.7	-1.1	-1.5	-1.3	-1.9	-0.8	-2.7	-1.5	-1.9	-1.1	1.3
Weight	0.4	1.9	6.3	-1.0	1.7	2.5	2.0	-0.4	-0.7	0.3	-0.1	-2.4	-1.3	-0.7	-1.2	-1.6	-1.6	-0.7	-0.7	0.2	-1.9	-1.0	-1.6	1.3
Impedance of arm (right)	0.1	0.4	2.5	0.2	-0.6	-1.0	-0.6	-0.8	-1.2	-0.1	-0.5	1.0	-0.3	-0.9	0.1	0.1	0.5	0.2	1.6	-0.2	0.1	0.2	-0.4	-0.6
Arm fat percentage (right)	0.3	1.1	2.8	0.2	-0.8	-0.8	-0.7	1.6	1.6	1.3	1.2	0.6	1.0	1.6	1.1	1.7	0.8	1.3	-0.1	1.1	1.2	0.3	-0.3	-0.3
Trunk fat-free mass	0.6	3.3	11.2	-0.6	2.2	3.3	2.5	-1.4	-1.5	-1.3	-0.6	-3.2	-1.7	-1.3	-1.8	-2.8	-1.9	-1.0	-0.5	0.4	-2.8	-0.7	-1.0	1.2
Hip circumference	0.2	1.0	2.6	-1.2	1.0	1.6	1.2	0.1	-0.2	-0.3	0.2	-1.6	-0.7	-0.4	-0.5	-1.2	-1.1	-0.9	-0.7	-0.0	-1.5	-1.2	-1.4	0.8
Time employed in main current job	0.7	0.9	3.0	0.1	1.2	1.7	1.2	-1.2	-0.2	0.5	-0.9	-1.1	-1.1	-0.4	-1.0	-0.6	-1.3	0.0	-1.2	-1.1	0.1	-0.0	0.2	1.2
Alcohol intake versus 10 years previously	1.0	1.4	8.0	0.4	-1.4	-1.8	-1.4	0.5	0.6	-1.2	1.4	1.3	1.1	0.5	1.5	0.2	1.2	0.6	2.8	0.8	0.7	0.0	0.4	-1.5
Father’s age at death	0.4	0.5	3.1	-0.1	-0.6	-1.2	-0.5	0.9	1.1	-1.8	0.7	0.5	0.9	0.8	0.8	0.6	0.6	-0.1	0.1	0.1	0.7	-0.4	0.2	-0.3
Worrier / anxious feelings	0.3	0.7	4.9	-0.7	0.1	-0.1	0.1	-1.2	-0.5	0.4	-0.8	0.2	-0.6	-1.1	-0.4	-0.8	-0.5	-1.2	0.2	-2.2	-0.5	-0.8	-0.3	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	2.2	-1.4	0.2	-0.2	0.2	0.2	0.1	0.8	-0.2	-0.4	-0.2	-0.4	-0.1	-0.2	-0.4	-0.7	-0.6	-1.0	-0.7	-1.5	-0.9	0.4
Falls in the last year	0.3	0.4	1.8	-1.3	0.3	-0.2	0.3	0.4	-0.6	-0.5	-0.3	-0.2	-0.6	-1.1	-0.3	-0.5	-0.3	-0.5	-0.5	-0.9	-0.9	-1.0	-1.1	0.4
Hair/balding pattern: Pattern 3	0.3	0.5	1.6	-1.3	0.3	-0.7	0.3	0.4	-0.7	-0.0	0.5	-0.1	-0.5	-1.0	-0.0	-0.7	-0.3	-0.8	0.0	-0.3	-1.2	-1.0	-1.2	0.1
Number of live births	0.4	0.5	2.7	-0.2	0.7	1.6	0.9	1.2	-0.0	-0.4	-0.1	-1.0	-0.7	0.2	-0.5	-0.1	-0.5	-0.3	-1.1	0.6	-0.7	0.1	-0.2	0.5
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	12.0	-0.0	2.1	3.5	2.4	-2.7	-2.9	-1.9	-1.6	-2.5	-2.5	-2.3	-2.2	-2.9	-1.6	-1.3	0.2	-0.1	-2.2	-0.0	-0.2	0.8
Pulse rate	0.2	0.3	2.2	-0.4	0.2	-0.3	0.0	1.4	0.1	1.5	0.4	-0.2	-0.4	-0.0	-0.1	0.1	-0.3	-0.3	-0.6	0.0	0.1	-0.1	-0.5	0.4
Happiness	0.7	0.9	10.1	-0.2	0.7	0.2	0.7	0.7	-0.5	3.2	0.0	-0.7	-0.8	-0.6	-0.4	-1.5	-0.8	-0.3	1.0	0.2	-0.7	0.0	0.2	0.7
Noisy workplace	0.3	0.3	1.5	0.2	-0.3	-0.5	-0.4	0.5	0.9	-1.2	1.2	0.1	0.6	0.5	0.6	0.2	0.2	0.4	-0.6	0.1	0.6	0.3	0.4	-0.3
Qualifications: A levels/AS levels or equivalent	0.8	1.9	5.1	-0.8	1.2	1.0	1.3	-2.2	-0.9	-2.1	-1.8	-1.2	-1.4	-1.1	-1.5	-2.0	-1.1	-1.3	-0.7	-1.8	-1.0	-0.9	0.1	1.4
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	3.4	-1.1	0.9	0.7	0.9	-1.0	-1.3	1.4	-1.9	-0.7	-1.2	-1.0	-1.3	-1.8	-1.0	-1.0	0.1	-0.8	-0.7	-1.1	-0.5	0.9
Mouth/teeth dental problems: Dentures	0.5	0.8	4.0	0.1	0.0	0.0	0.0	1.9	2.0	-0.6	1.3	-0.5	0.8	1.5	0.6	0.8	0.1	0.3	-1.4	0.6	0.8	0.2	0.3	0.1
Asthma	0.3	0.5	2.8	-1.3	-0.1	-0.5	-0.3	-0.4	-0.2	-1.3	-0.2	0.1	0.3	-0.7	0.1	0.0	-0.0	-0.6	-0.0	-1.3	-0.7	-1.7	-1.1	-0.0
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	6.9	-2.3	0.6	0.8	0.7	-1.9	-1.3	-0.9	-1.9	-0.9	-0.9	-2.1	-1.1	-0.9	-1.1	-1.6	-0.5	-2.6	-1.8	-2.2	-1.8	1.0
Medication: Cholesterol lowering	0.1	0.2	1.1	-0.0	-0.3	-0.3	-0.5	0.5	0.6	0.7	0.6	0.3	0.9	0.3	0.5	1.1	0.1	-0.0	-0.2	-0.1	0.6	-0.1	0.1	-0.1
Depression (self-reported)	0.3	0.3	1.8	-0.9	-0.1	-0.3	-0.1	-0.3	-0.4	1.3	-0.2	0.1	-0.1	-0.6	-0.0	-0.4	-0.2	-0.5	-0.8	-0.9	-0.6	-0.8	-1.0	0.3
Medication: Lansoprazole	0.4	0.4	1.6	-1.2	0.2	-0.1	0.2	0.9	0.9	-1.2	0.4	-0.2	-0.1	0.6	0.2	0.1	-0.1	-0.7	-0.6	0.1	0.1	-1.1	-0.9	0.5
Prospective memory result	0.5	0.6	3.6	-1.2	0.5	-0.2	0.7	0.4	0.7	-1.2	0.2	-0.3	-0.3	-0.1	-0.1	-0.6	-0.5	-0.4	-1.9	-1.0	-0.7	-1.0	-0.5	0.7
Lung cancer (father)	0.2	0.2	1.0	0.1	-0.3	-0.0	-0.5	-0.3	-1.0	0.8	-0.0	0.2	-0.3	-1.0	0.0	-0.0	0.1	-0.4	0.8	-0.5	-0.0	0.1	-0.7	-0.5
Illnesses of mother	1.2	1.5	3.3	1.8	-0.8	-1.1	-0.6	1.4	1.4	0.9	1.1	0.9	1.2	1.5	0.8	0.7	0.8	1.6	0.6	1.6	1.2	1.8	1.7	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	6.6	0.7	0.7	2.1	1.1	-2.0	-2.0	-2.6	-0.9	-1.0	-1.2	-1.2	-0.9	-1.6	-0.2	-0.4	0.6	0.7	-1.3	0.7	0.3	-0.4
Pulse wave Arterial Stiffness index	0.4	0.4	2.4	-0.2	0.9	0.8	1.0	0.1	-0.1	-1.1	-0.6	-0.8	-0.3	-0.1	-0.8	-0.1	-0.6	-0.0	-1.6	-0.1	-0.5	-0.3	-0.2	0.6
Impedance of arm (left)	0.1	0.3	1.2	-0.2	-0.1	-0.3	-0.0	-1.0	-1.0	-0.9	-1.1	0.5	-0.4	-1.0	-0.4	-0.1	0.0	-0.2	0.2	-0.9	-0.3	-0.2	-0.6	0.0
Arm fat mass (right)	0.1	0.3	0.9	-0.1	0.1	0.4	0.3	0.9	0.9	1.0	0.7	-0.5	0.3	0.9	0.3	0.5	-0.1	0.7	-0.2	0.8	0.1	-0.1	-0.5	0.3
Trunk predicted mass	0.6	3.3	10.8	-0.6	2.2	3.3	2.5	-1.3	-1.4	-1.4	-0.5	-3.2	-1.7	-1.2	-1.7	-2.8	-1.8	-1.0	-0.6	0.5	-2.7	-0.7	-0.9	1.2
Standing height	1.3	13.3	32.8	-1.2	4.2	5.5	4.5	-3.5	-4.4	-2.2	-2.2	-5.2	-4.1	-3.9	-3.9	-5.7	-3.8	-2.5	-0.3	-0.4	-5.0	-1.4	-2.5	2.5
Length of working week for main job	0.3	0.4	2.7	0.2	-0.6	-1.0	-0.6	-0.5	-0.4	0.4	-0.1	0.6	0.3	-0.4	0.4	-0.9	0.4	0.3	1.6	0.3	0.4	-0.1	-0.1	-0.5
Exposure to tobacco smoke at home	2.3	2.6	4.3	-1.6	1.8	1.6	1.7	-0.7	-1.5	0.1	-1.6	-1.6	-2.1	-1.7	-1.8	-1.8	-1.6	-1.8	-1.7	-1.3	-2.0	-1.0	-1.9	1.4
Breastfed as a baby	0.3	0.4	3.4	0.2	-0.3	-0.0	-0.1	0.1	0.8	-1.9	0.4	0.3	0.4	0.7	0.4	0.2	0.3	0.5	-0.6	0.3	0.6	0.4	0.9	-0.2
Tense / ‘highly strung’	0.3	0.5	3.1	-0.9	0.0	-0.2	-0.1	-0.9	-0.5	0.5	-0.4	0.1	-0.6	-1.1	-0.2	-0.0	-0.3	-1.1	0.2	-1.8	-0.2	-1.1	-0.7	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.4	-0.9	-0.6	-0.6	-0.6	0.0	0.3	-1.5	0.4	0.5	0.4	-0.3	0.6	-0.4	0.4	-0.7	-0.8	-1.0	-0.5	-0.9	-1.0	-0.3
Hair/balding pattern: Pattern 4	0.5	1.1	3.9	1.1	-0.2	0.4	-0.2	1.9	2.0	1.9	0.8	-0.2	0.9	1.5	0.5	0.7	0.1	0.7	-0.4	0.5	1.4	1.0	1.6	0.0
Birth weight of first child	0.6	1.0	5.0	-1.5	0.8	1.3	0.8	-0.3	-0.7	-2.2	-0.7	-1.5	-0.9	-0.4	-0.7	-1.1	-0.4	-1.1	-0.7	0.5	-1.3	-1.3	-0.6	0.3
Peak expiratory flow (PEF)	0.3	0.6	3.9	0.4	0.3	1.0	0.5	-2.0	-1.4	-0.7	-0.5	-0.4	-0.6	-1.0	-0.5	-1.0	-0.1	-0.3	1.0	-0.0	-0.8	0.2	0.7	-0.3
Pulse wave reflection index	0.1	0.1	0.3	0.1	0.3	0.4	0.3	0.1	-0.5	-0.1	-0.2	-0.4	-0.2	-0.3	-0.3	0.1	-0.1	-0.1	-0.3	0.4	-0.4	0.1	-0.2	-0.1
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.5	-2.1	0.5	-0.3	0.6	-0.4	-0.8	0.2	-1.2	-0.4	-0.9	-1.2	-0.8	-0.5	-0.7	-1.0	-1.5	-1.5	-1.6	-1.8	-1.6	0.9
Loud music exposure frequency	6.1	6.7	10.8	2.3	-3.0	-3.3	-2.9	1.7	2.4	-1.1	3.2	3.0	2.7	2.5	3.1	2.3	3.0	2.6	2.1	2.2	2.6	2.3	2.3	-2.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.8	-0.5	0.4	0.4	0.7	-1.9	-0.8	-0.5	-1.3	-0.3	-0.8	-0.9	-0.7	-0.9	-0.5	-0.6	0.6	-1.1	-0.7	-0.7	0.3	0.5
Mouth/teeth dental problems: Bleeding gums	3.0	3.8	6.4	-2.3	2.0	1.4	2.2	-1.3	-1.6	0.0	-2.4	-1.4	-2.0	-2.0	-2.2	-2.1	-2.0	-2.1	-1.4	-2.2	-2.5	-2.1	-2.0	2.3
Blood clot in the leg (DVT)	2.5	3.2	6.1	1.2	-1.9	-1.9	-1.9	2.1	2.1	-0.8	2.5	1.8	2.3	2.0	2.2	1.8	1.9	1.7	0.4	1.7	1.8	1.1	1.2	-1.8
Medication: Paracetamol	0.3	0.5	1.4	-0.8	-1.2	-0.5	-1.0	-1.0	-0.2	0.2	0.3	1.0	0.8	-0.5	0.9	0.5	0.8	-0.1	0.7	-0.9	-0.4	-0.7	-0.2	-0.8
Headache pain in last month	3.7	6.4	10.0	-3.1	2.0	2.3	2.4	-3.2	-3.0	-0.2	-2.7	-2.4	-2.8	-2.8	-2.4	-2.6	-2.3	-2.3	-1.5	-2.5	-3.1	-3.0	-2.9	2.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	2.9	-0.7	1.1	1.0	1.2	-1.7	-1.3	-1.0	-1.5	-0.8	-1.4	-1.0	-1.3	-1.2	-0.9	-0.7	-0.4	-0.8	-1.4	-0.7	-0.5	0.8
Glaucoma (self-reported)	1.1	1.3	2.8	0.9	-1.6	-1.0	-1.6	0.0	-0.1	0.2	1.2	1.5	1.1	0.1	1.5	1.5	1.5	1.1	1.4	0.7	1.2	1.1	0.5	-1.7
Gout (self-reported)	1.2	1.7	3.7	-1.5	1.5	1.0	1.3	-1.0	-0.6	0.7	-1.3	-1.5	-1.1	-1.1	-1.4	-1.3	-1.6	-1.7	0.0	-1.7	-1.0	-1.9	-0.2	1.7
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	4.3	-1.3	1.7	2.1	1.7	-1.3	-1.8	-0.7	-1.4	-1.8	-1.8	-1.7	-1.7	-1.6	-1.5	-1.1	-1.2	-1.1	-1.8	-1.2	-1.9	1.2
Medication: Amlodipine	1.4	1.9	4.4	-1.2	1.8	2.0	1.8	0.8	-0.2	0.7	-1.2	-1.9	-1.6	-0.1	-1.6	-1.5	-1.7	-1.0	-2.1	-0.3	-1.1	-0.9	-1.0	1.9
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.5	-0.5	-0.1	-0.4	-0.5	0.1	-0.2	-0.7	0.2	0.3	0.2	-0.3	0.2	-0.5	0.1	-0.7	-0.3	-0.3	-0.3	-0.6	-0.3	-0.2
Birth weight	1.9	4.1	11.7	-1.2	2.6	3.4	2.5	-0.5	-1.0	-2.3	-1.9	-3.2	-2.3	-1.0	-2.4	-2.1	-2.0	-1.1	-3.0	-0.5	-1.9	-0.8	-0.8	1.9
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.3	-1.2	1.3	0.9	0.9	-0.4	-0.8	0.2	-0.7	-1.7	-1.4	-1.3	-1.0	-2.1	-1.4	-2.0	-0.5	-1.4	-0.6	-1.3	-0.9	1.5
High blood pressure (siblings)	0.2	0.3	1.5	-0.4	0.1	-0.0	0.0	0.1	-0.5	1.2	-0.1	-0.1	-0.2	-0.8	-0.1	0.2	-0.3	-0.6	0.2	-0.8	-0.4	-0.5	-1.1	0.3
Forced vital capacity (FVC), Best measure	0.7	2.4	7.9	0.6	1.1	2.8	1.5	-2.6	-2.3	-2.7	-1.2	-1.6	-1.5	-1.6	-1.4	-2.1	-0.7	-0.7	0.7	0.2	-1.8	0.4	0.2	-0.1
Body fat percentage	0.1	0.3	2.1	-0.3	-0.2	-0.2	-0.1	0.8	0.5	1.5	0.7	0.1	0.4	0.5	0.4	0.8	0.1	0.6	0.1	0.4	0.4	-0.3	-1.2	0.1
Leg fat percentage (right)	0.2	0.7	3.7	-0.2	-0.6	-0.9	-0.5	1.0	0.8	1.9	1.1	0.6	0.7	0.6	0.9	1.2	0.4	0.6	0.1	0.2	0.7	-0.2	-1.0	-0.2
Arm fat-free mass (right)	0.5	2.8	8.8	-0.6	2.1	3.0	2.2	-1.3	-1.5	-0.6	-0.4	-2.8	-1.5	-1.3	-1.6	-2.5	-1.9	-1.0	-0.5	0.2	-2.5	-0.8	-1.2	1.2
Exposure to tobacco smoke outside home	2.0	2.7	7.0	-2.6	1.7	1.1	1.5	-0.6	-0.4	-0.5	-1.2	-1.6	-1.5	-1.1	-1.4	-1.9	-1.6	-2.4	-1.7	-2.0	-0.9	-2.4	-1.8	2.0
Comparative body size at age 10	0.6	1.6	4.6	-0.6	1.6	1.9	1.7	-0.3	1.3	-2.1	-0.6	-1.8	-1.4	0.9	-1.0	-1.2	-1.2	-0.5	-1.6	-0.4	0.5	-0.7	1.2	1.6
Number of full brothers	0.3	0.4	1.4	-0.2	0.8	0.9	0.7	1.0	0.2	0.1	-0.9	-1.0	-0.7	0.3	-0.9	0.2	-0.5	0.1	-1.2	0.2	-0.4	-0.1	-0.7	0.5
Worry too long after embarrassment	0.2	0.4	2.0	-0.0	0.6	0.6	0.5	-0.6	0.0	-0.2	-0.8	-0.4	-0.6	-0.3	-0.6	-0.5	-0.8	-0.7	-0.1	-1.4	-0.2	-0.3	0.9	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	-0.0	-1.0	-0.9	-1.1	-0.4	-0.2	-1.3	0.1	1.1	0.4	-0.3	0.6	0.2	0.8	0.0	-0.0	-0.7	0.1	-0.0	-0.4	-0.7
Wheeze or whistling in the chest in last year	0.5	0.9	2.8	-1.7	-0.1	0.1	-0.3	-0.9	-0.9	-1.1	-1.2	0.1	-0.3	-1.1	-0.3	0.2	-0.1	-0.5	-1.4	-1.5	-0.6	-1.5	-1.7	0.2
Number of children fathered	0.3	0.3	1.7	0.7	0.5	0.7	0.6	-0.2	0.3	-0.7	-0.2	-0.3	0.0	0.8	-0.5	1.0	-0.2	0.7	-1.3	0.6	0.2	0.6	0.0	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	1.8	1.1	-1.1	-0.9	-1.2	-0.6	0.7	-1.0	0.7	1.3	1.2	0.9	1.1	0.5	1.1	0.9	0.8	0.7	1.2	0.7	1.1	-1.1
Age at first live birth	2.7	4.7	10.4	-2.1	2.3	1.9	2.4	-2.4	-1.7	-1.2	-3.2	-2.0	-1.9	-1.9	-2.6	-1.8	-2.2	-2.6	-1.8	-2.6	-2.3	-2.3	-1.1	2.5
Pulse wave peak to peak time	0.2	0.3	2.2	0.1	-0.6	-0.5	-0.7	-0.3	-0.0	1.0	0.5	0.6	0.1	-0.1	0.6	-0.3	0.3	-0.1	1.5	-0.0	0.2	0.2	0.1	-0.4
Health satisfaction	2.3	2.9	5.0	-2.1	1.9	1.7	1.9	-0.3	-1.3	1.2	-1.4	-1.8	-2.0	-1.7	-1.8	-1.9	-1.9	-2.2	-1.4	-1.7	-1.6	-1.8	-1.6	1.9
Shortness of breath walking on level ground	0.9	1.0	3.8	-1.6	0.4	-0.1	0.2	-0.3	-0.8	0.7	-0.7	-0.3	-1.0	-1.5	-0.6	-1.2	-0.7	-1.1	-0.6	-1.9	-1.0	-1.3	-1.7	0.7
Qualifications: College or University degree	1.0	3.3	6.8	-1.7	2.0	1.3	2.1	-2.0	-0.6	-1.8	-2.6	-1.6	-1.7	-0.9	-2.1	-2.4	-1.9	-1.8	-1.4	-2.1	-1.2	-2.0	0.0	2.6
Eye problems/disorders: None of the above	0.6	0.7	10.6	-0.4	0.4	0.2	0.3	-0.6	0.5	-3.3	-0.1	-0.4	-0.0	0.6	-0.3	-0.6	-0.0	-0.2	-1.1	0.1	-0.4	-0.5	0.5	0.1
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.4	-0.4	0.4	-0.1	0.2	1.2	0.5	0.3	0.4	-0.5	-0.0	-0.3	-0.1	-0.6	-0.5	-0.6	-0.9	-1.0	-0.0	-0.5	-0.6	0.8
Emphysema/chronic bronchitis	0.4	0.5	2.2	-0.6	0.7	0.4	0.6	0.8	0.4	-0.5	-0.3	-0.8	-0.3	0.1	-0.5	-1.0	-0.7	-0.7	-1.5	-0.5	-0.2	-0.7	-0.4	0.8
Medication for pain relief, constipation, heartburn	2.2	3.7	8.5	2.9	-1.2	-1.4	-1.1	1.9	1.7	-0.2	1.9	1.4	1.4	2.3	1.5	1.5	1.7	2.5	1.2	2.7	2.2	2.9	2.7	-1.6
Neck or shoulder pain in last month	0.2	0.3	2.8	-0.8	-0.2	-0.0	-0.2	-0.8	-0.7	-1.7	-0.2	0.2	-0.2	-0.1	0.0	-0.2	0.3	-0.3	0.1	0.3	-0.4	-0.9	-0.7	-0.4
Medication: Blood pressure	0.3	0.5	3.1	0.4	-0.2	-0.5	-0.2	1.8	1.0	1.2	1.2	0.1	0.5	0.7	0.6	0.4	0.2	0.2	0.0	0.7	0.8	0.4	0.2	-0.1
Angina (self-reported)	1.6	2.2	7.2	-1.8	1.4	1.5	1.0	-1.0	0.4	-0.0	-1.2	-1.6	-0.8	-0.7	-1.2	-2.1	-1.8	-1.8	-1.5	-2.7	-0.8	-2.0	-1.2	1.7
Migraine (self-reported)	0.6	0.7	2.5	-0.8	0.6	0.6	0.7	-1.1	-1.6	0.7	-1.2	-0.4	-1.3	-0.9	-0.9	-0.8	-0.5	-0.3	0.1	-0.3	-0.8	-0.7	-1.3	0.5
Medication: Ibuprofen	0.9	1.0	3.5	-1.6	0.4	0.6	0.5	-1.0	-1.0	-0.5	-1.3	-0.5	-0.6	-1.6	-0.8	-0.1	-0.7	-0.9	-0.5	-1.9	-1.3	-1.3	-1.4	0.6
Medication: Allopurinol	1.6	2.1	3.8	-1.7	1.7	1.6	1.3	-0.9	-1.2	1.0	-1.6	-1.7	-1.5	-1.4	-1.6	-1.2	-1.6	-2.0	-0.1	-1.5	-1.4	-1.9	-0.8	1.5
Medication: Omeprazole	0.3	0.3	1.5	-1.1	0.2	0.3	-0.0	0.3	0.5	-0.2	-0.2	-0.3	0.1	-0.0	-0.1	-0.5	-0.4	-0.9	-1.2	-1.0	0.2	-1.0	-0.7	0.5
Medication: Seretide 50 evohaler	0.1	0.1	0.4	-0.2	0.3	0.2	0.3	0.4	0.2	0.1	0.2	-0.5	-0.1	0.2	-0.2	-0.2	-0.4	-0.3	-0.2	0.0	-0.6	-0.4	-0.1	0.3
Mean time to correctly identify matches	4.1	7.7	12.0	-2.6	3.2	3.0	2.9	-0.6	-2.3	1.7	-2.6	-3.5	-3.0	-3.2	-3.1	-2.8	-3.3	-2.8	-2.4	-2.9	-2.9	-2.3	-2.9	3.1
Heart disease (mother)	0.0	0.1	0.3	-0.5	0.1	0.0	-0.1	-0.4	-0.3	0.2	0.1	0.1	-0.3	-0.0	-0.0	-0.0	-0.1	-0.0	0.3	0.2	-0.2	-0.5	-0.3	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.5	-0.9	0.1	0.2	0.3	-1.6	-1.2	-0.5	-0.3	0.1	-0.7	-0.9	-0.2	-1.0	0.0	-0.3	0.3	0.1	-1.0	-0.8	-1.1	-0.3
Whole body fat mass	0.1	0.3	1.3	-0.4	0.6	0.9	0.8	0.3	0.2	1.1	0.3	-1.0	-0.2	0.1	-0.3	-0.1	-0.6	0.2	-0.2	0.4	-0.4	-0.4	-1.2	0.6
Leg fat mass (right)	0.1	0.3	1.6	-0.2	0.2	0.4	0.4	0.7	0.5	1.3	0.7	-0.5	0.2	0.4	0.2	0.5	-0.2	0.4	-0.3	0.5	0.0	-0.2	-1.0	0.3
Arm predicted mass (right)	0.6	3.0	9.4	-0.8	2.1	3.1	2.3	-1.3	-1.5	-1.0	-0.4	-2.9	-1.6	-1.4	-1.6	-2.6	-1.9	-1.1	-0.6	0.1	-2.5	-0.9	-1.4	1.2
Pulse rate, automated reading	0.1	0.3	1.1	-0.9	-0.2	-1.1	-0.2	0.5	-0.1	1.0	0.2	0.3	-0.0	-0.5	0.2	-0.1	0.0	-0.5	-0.1	-0.3	-0.4	-0.7	-1.1	-0.0
Alcohol intake frequency.	0.1	0.2	1.0	-0.0	0.3	0.2	0.6	0.4	1.0	-0.3	-0.0	-0.1	0.1	1.0	-0.0	-0.1	-0.3	0.3	-0.3	0.4	0.4	-0.1	0.9	0.6
Comparative height size at age 10	1.3	7.4	19.1	-0.8	3.4	4.2	3.5	-1.7	-3.1	-0.3	-1.4	-4.3	-3.1	-2.5	-3.0	-4.4	-2.7	-1.9	-0.4	0.2	-3.8	-0.9	-2.4	1.9
Number of full sisters	0.5	0.6	3.4	-0.1	-0.8	-0.8	-1.1	0.2	-0.4	-0.6	0.3	0.7	0.5	0.2	0.6	0.0	1.0	0.3	1.8	1.0	0.0	-0.1	0.7	-1.1
Suffer from ‘nerves’	0.1	0.1	0.5	0.4	-0.3	-0.4	-0.4	0.1	0.3	0.6	-0.0	0.5	0.3	0.1	0.2	0.4	0.2	0.2	0.1	-0.2	0.1	0.4	0.7	-0.2
Overall health rating	0.4	0.8	4.3	-1.7	0.5	-0.0	0.3	0.7	-0.4	2.1	-0.6	-0.3	-0.5	-0.4	-0.5	0.1	-0.6	-0.8	-0.3	-0.5	-0.8	-1.6	-1.4	0.7
Chest pain or discomfort	0.7	1.0	3.2	-1.5	0.7	0.8	0.9	-0.9	-0.9	0.3	-0.9	-0.7	-0.9	-0.9	-0.8	-1.6	-0.8	-0.9	-0.3	-0.6	-1.2	-1.6	-1.8	0.7
Had major operations	2.9	3.4	6.2	1.4	-2.0	-2.0	-2.1	2.5	1.7	-0.2	1.7	2.1	2.3	1.9	2.0	2.5	2.1	1.4	1.1	1.7	2.2	1.3	1.2	-1.7
Age at last live birth	2.1	3.1	5.3	-1.5	2.2	1.6	2.3	-1.4	-0.9	-1.1	-2.3	-1.9	-1.7	-1.0	-2.2	-1.9	-1.9	-1.9	-1.9	-1.7	-1.6	-1.7	-0.7	2.2
Family relationship satisfaction	0.2	0.2	0.7	0.1	-0.3	-0.8	-0.5	0.7	0.6	0.8	0.3	0.3	0.4	0.1	0.3	0.1	0.0	-0.1	-0.4	-0.5	0.8	0.1	0.4	0.1
Leg pain on walking	0.4	0.5	5.2	-1.1	-0.1	-0.4	-0.1	0.2	0.3	-2.3	0.6	-0.0	-0.1	-0.3	0.3	0.3	0.2	-0.6	-1.0	-0.8	-0.1	-0.9	-0.7	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.8	-0.5	0.1	0.6	0.3	-0.7	-1.2	-0.2	-0.5	-0.4	-0.6	-0.6	-0.3	0.2	0.0	0.2	-0.1	0.4	-0.7	-0.3	-1.3	-0.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.7	0.1	-1.1	-0.7	-0.8	0.7	-0.0	-0.5	1.1	1.0	0.9	0.2	1.1	0.9	1.1	0.4	1.3	1.1	0.0	0.3	-0.1	-1.0
Illness, injury, bereavement, stress in last 2 years	2.6	3.2	5.3	2.1	-1.7	-1.3	-1.6	1.5	2.0	-1.6	2.1	1.7	1.8	1.8	2.0	2.1	1.8	1.7	0.2	1.4	1.8	2.3	1.9	-1.8
Medication: Aspirin	3.2	4.3	9.2	-2.8	1.7	1.6	1.6	-2.5	-2.0	-0.5	-1.6	-1.7	-1.7	-2.5	-1.7	-1.7	-2.1	-2.6	-1.0	-2.6	-2.1	-3.0	-2.7	2.0
Supplements: Vitamin C	0.3	0.3	0.8	0.9	-0.3	-0.3	-0.5	0.3	0.9	0.5	0.4	0.1	0.6	0.6	0.4	0.3	0.2	0.8	-0.6	-0.3	0.9	0.9	0.8	-0.1
Knee pain experienced in last month	3.9	6.1	10.2	-3.0	2.3	1.8	2.4	-2.6	-2.6	0.3	-2.7	-2.2	-2.6	-2.8	-2.5	-2.7	-2.5	-3.1	-0.6	-2.8	-2.4	-3.2	-2.4	2.4
Hypertension (Self-reported)	0.6	1.7	3.6	-1.4	1.7	1.6	1.9	0.1	-0.5	1.0	-0.4	-1.8	-1.5	-0.7	-1.2	-1.2	-1.8	-1.1	-1.3	-0.5	-1.7	-1.2	-1.3	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.2	-1.1	1.1	0.9	1.1	0.1	-0.8	-0.7	-0.5	-1.1	-1.2	-1.2	-0.9	-0.6	-1.1	-0.9	-1.3	-0.6	-1.2	-0.6	-1.8	1.0
Illnesses of father: Heart disease	0.7	1.0	3.4	1.4	-0.7	-0.9	-0.9	0.1	-0.1	0.8	0.5	0.8	0.5	0.9	0.4	1.8	1.0	1.5	0.5	1.9	0.6	1.4	0.4	-1.0
Illnesses of siblings: Diabetes	0.4	0.4	1.9	-0.8	-0.2	-0.5	-0.1	1.1	1.4	-0.7	0.9	0.1	0.5	1.1	0.6	-0.1	0.1	-0.2	-0.3	0.3	0.1	-0.9	0.9	-0.0
Smoking status: Previous	0.6	0.9	2.8	-1.3	0.7	0.8	0.8	-0.2	-1.3	0.2	-0.4	-0.8	-1.0	-1.4	-0.6	-1.0	-0.8	-1.2	-0.4	-0.9	-1.3	-1.1	-1.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	12.7	0.0	0.3	1.3	0.7	-1.4	-1.7	-3.6	-0.7	-0.7	-0.7	-1.0	-0.6	-1.1	0.0	-0.5	0.5	0.4	-1.9	-0.0	-0.4	-0.5
Whole body fat-free mass	0.5	2.8	10.1	-0.5	2.1	3.2	2.4	-1.0	-1.1	-1.0	-0.3	-3.1	-1.5	-1.0	-1.6	-2.6	-1.8	-0.9	-0.5	0.5	-2.4	-0.6	-0.8	1.2
Leg fat-free mass (right)	0.4	2.3	9.4	-0.4	2.1	3.1	2.2	-0.4	-0.6	-0.8	-0.1	-3.0	-1.3	-0.5	-1.4	-2.1	-1.7	-0.7	-0.8	0.6	-2.0	-0.5	-0.5	1.3
Arm fat percentage (left)	0.2	0.8	2.6	-0.0	-0.5	-0.3	-0.3	1.5	1.6	1.0	0.9	0.2	0.8	1.5	0.8	1.5	0.5	1.1	-0.7	0.7	1.0	0.1	-0.4	0.1
Average weekly red wine intake	0.2	0.3	2.0	0.6	-0.2	-0.4	-0.0	-0.9	0.3	-1.4	0.3	0.4	0.2	0.1	0.2	0.5	0.2	0.7	0.6	-0.1	0.7	0.4	0.8	-0.2
Handedness (chirality/laterality): Left-handed	0.7	0.8	1.9	0.5	-1.3	-1.3	-1.4	-0.1	0.3	-0.5	0.6	1.2	1.3	0.2	1.1	0.9	1.1	0.2	1.2	-0.2	1.0	0.2	0.7	-1.1
Mood swings	1.1	2.0	4.2	-1.9	1.4	1.2	1.5	-0.1	-0.2	0.5	-1.4	-1.4	-1.3	-0.6	-1.4	-1.2	-1.5	-1.6	-1.9	-1.8	-1.4	-2.1	-1.1	1.9
Loneliness, isolation	1.2	1.7	4.3	1.3	-1.7	-1.8	-1.9	0.7	-0.3	0.7	0.6	2.1	1.3	0.3	1.2	1.4	1.6	1.3	1.8	0.9	0.9	1.0	-0.1	-1.7
Long-standing illness, disability or infirmity	1.1	1.7	4.7	-1.8	1.0	0.5	1.1	-1.2	-1.9	1.2	-1.3	-1.1	-1.4	-1.2	-1.2	-1.3	-0.9	-1.1	0.8	0.0	-1.6	-1.9	-2.2	0.8
Ever had bowel cancer screening	1.2	1.4	3.0	-1.4	1.3	0.9	1.4	-1.0	-0.1	-1.5	-0.5	-1.1	-1.0	-0.9	-0.9	-1.4	-1.3	-1.4	-0.7	-1.5	-1.1	-1.7	-1.1	1.2
Diabetes diagnosed by doctor	0.5	0.8	3.2	0.2	-0.5	-0.6	-0.5	1.1	1.8	-0.5	0.7	0.4	1.2	1.7	0.8	1.4	0.7	0.5	-0.3	0.6	1.2	-0.1	1.1	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.8	-0.6	-0.2	-0.1	0.1	0.5	0.2	0.5	-0.2	0.3	0.2	0.1	0.2	0.9	0.2	0.2	-0.7	-0.4	-0.2	-0.4	-0.0	-0.0
Friendships satisfaction	2.1	2.6	3.8	-1.6	1.7	1.2	1.6	-0.7	-1.6	1.8	-1.7	-1.6	-1.9	-1.8	-1.8	-1.9	-1.9	-1.6	-0.8	-1.4	-1.7	-1.3	-1.6	1.9
Qualifications: nursing, teaching	0.5	0.8	5.4	0.0	0.1	0.4	0.4	-2.2	-1.0	-2.3	-0.3	-0.3	-0.3	-0.7	-0.2	-1.4	-0.2	-0.3	1.3	-0.4	-0.4	-0.6	-0.1	-0.1
Commuting to job workplace: Walk	1.8	1.9	4.4	-1.1	1.6	1.1	1.4	-1.0	0.2	0.9	-1.8	-1.4	-1.3	-0.4	-1.6	-1.8	-1.8	-1.5	-1.8	-1.9	-0.1	-1.3	-0.2	2.1
Eye problems/disorders: Cataract	0.5	0.6	3.7	0.8	-0.0	-0.3	-0.1	1.9	0.8	1.9	0.9	-0.1	0.0	0.6	0.4	-0.2	-0.0	0.5	0.2	0.8	1.0	1.0	0.5	0.2
Mouth/teeth dental problems: Mouth ulcers	1.2	2.0	3.6	0.7	-1.7	-1.1	-1.6	1.1	1.3	-1.0	0.9	1.5	1.4	1.8	1.5	1.9	1.8	1.8	-0.1	1.6	1.4	1.1	1.1	-1.6
Medication for cholesterol	3.3	5.0	9.1	2.2	-2.4	-2.2	-2.4	2.3	2.4	-2.2	1.8	2.5	2.6	2.2	2.3	2.3	2.5	1.7	0.7	1.4	3.0	2.3	2.2	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.1	-0.6	1.1	0.8	1.1	-0.3	-0.3	-0.1	-0.8	-0.8	-1.2	-0.3	-1.0	-0.4	-0.8	-0.1	-1.8	-0.5	-0.8	-0.2	-0.8	1.0
Back pain experienced in last month	1.4	2.0	7.6	-1.8	1.3	0.8	1.3	-0.6	-1.5	1.1	-1.3	-1.2	-1.4	-1.4	-1.4	-1.3	-1.4	-1.0	-1.3	-0.9	-1.5	-1.6	-2.8	1.2
Mineral and other dietary supplements	0.5	0.7	4.2	-0.1	-1.0	-0.5	-1.0	-0.9	-1.2	0.6	0.3	1.1	-0.1	-0.8	0.7	0.1	0.8	0.4	2.0	0.3	-0.2	0.1	-0.7	-1.2
Breast cancer (self-reported)	0.4	0.5	1.2	0.4	-0.7	-1.0	-0.6	0.9	0.2	1.1	0.7	1.0	0.7	0.6	0.7	0.7	0.7	0.8	0.1	0.9	0.7	0.6	-0.1	-0.6
Asthma (self-reported)	0.3	0.7	3.5	-1.5	0.1	-0.2	-0.0	-0.5	-0.1	-1.4	-0.5	-0.1	0.2	-0.7	-0.1	0.0	-0.2	-0.8	-0.5	-1.6	-0.8	-1.9	-1.0	0.3
Osteoporosis (self-reported)	0.5	0.6	3.6	-0.6	0.7	0.4	0.7	0.3	-0.6	-0.8	-0.7	-0.5	-0.4	-0.4	-0.8	0.6	-0.6	-0.5	-1.3	-0.3	-0.6	-0.6	-1.9	0.8
Osteoarthritis (self-reported)	0.1	0.2	0.6	0.7	0.0	-0.2	0.0	0.5	0.1	0.8	-0.1	-0.1	0.2	0.5	-0.2	0.5	0.2	0.3	0.4	0.6	0.3	0.7	0.2	-0.1
Medication: Aspirin	3.0	3.9	7.8	-2.6	1.5	1.3	1.4	-2.7	-2.3	-0.3	-1.6	-1.4	-1.6	-2.6	-1.6	-1.6	-1.9	-2.4	-0.5	-2.5	-2.1	-2.8	-2.7	1.7
Medication: Gliclazide	2.3	2.6	6.4	1.3	-1.0	-1.4	-1.2	2.5	2.4	-0.2	2.0	0.8	1.7	2.4	1.5	1.6	1.3	1.5	0.4	1.7	2.1	1.2	1.9	-1.0
Illnesses of father: None of the above (group 1)	0.2	0.3	1.7	-0.8	-0.1	-0.2	0.1	-0.6	0.1	-0.9	0.4	0.1	0.1	-0.6	0.2	-0.7	-0.2	-0.5	-0.8	-1.3	-0.6	-0.6	-0.2	0.1
Smoking status: Current	0.4	0.6	1.7	0.4	-0.8	-1.1	-1.2	1.0	0.2	0.9	0.6	1.0	0.7	0.1	0.7	1.3	0.7	0.6	-0.2	0.0	1.0	0.6	0.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	5.3	0.3	0.6	1.5	0.6	0.0	0.8	-2.3	0.0	-1.0	-0.2	0.8	-0.3	-1.2	-0.1	-0.4	-1.3	0.6	0.3	0.3	1.3	0.1
Whole body water mass	0.5	3.0	10.8	-0.6	2.2	3.3	2.4	-1.1	-1.2	-1.0	-0.4	-3.2	-1.6	-1.1	-1.7	-2.6	-1.9	-1.0	-0.6	0.4	-2.5	-0.7	-0.9	1.3
Leg predicted mass (right)	0.4	2.1	8.8	-0.4	2.0	3.0	2.1	-0.4	-0.6	-0.8	-0.1	-2.9	-1.3	-0.4	-1.3	-2.1	-1.6	-0.6	-0.7	0.6	-1.9	-0.5	-0.3	1.2
Arm fat mass (left)	0.1	0.3	1.1	-0.2	0.2	0.6	0.5	0.9	1.0	0.9	0.6	-0.6	0.3	0.9	0.2	0.6	-0.2	0.6	-0.7	0.6	0.1	-0.1	-0.6	0.4
Number of self-reported non-cancer illnesses	0.4	0.6	3.4	-1.1	0.6	-0.0	0.6	-0.7	-0.7	0.1	0.1	-0.6	-0.7	-0.8	-0.3	-1.0	-0.7	-0.6	0.3	-0.4	-0.9	-1.3	-1.9	0.5
Average weekly champagne plus white wine intake	2.5	3.4	7.0	-1.8	1.7	1.9	1.6	-2.0	-2.1	-0.4	-1.4	-2.0	-2.1	-2.4	-1.6	-2.6	-1.8	-2.1	-0.4	-1.5	-2.1	-1.7	-2.2	1.5
Miserableness	0.1	0.1	0.9	0.1	0.0	-0.1	0.2	0.9	0.6	0.6	0.0	-0.1	0.3	0.4	0.0	-0.0	-0.1	0.1	-0.2	-0.0	-0.1	-0.0	0.5	0.3
Guilty feelings	0.5	0.7	2.2	-0.8	0.7	0.6	0.7	0.9	1.4	0.3	-0.7	-0.7	-0.2	0.6	-0.5	-0.1	-0.8	-0.9	-1.5	-1.3	-0.0	-0.9	1.0	1.4
Wears glasses or contact lenses	0.6	0.7	2.3	0.1	1.0	1.5	0.9	0.1	0.5	0.9	0.1	-1.4	-0.5	0.1	-0.5	-0.7	-1.2	-0.7	-1.4	-0.6	0.2	-0.0	0.6	1.1
Ever taken oral contraceptive pill	0.2	0.2	0.7	-0.8	-0.0	-0.4	0.2	0.2	-0.2	-0.2	-0.7	0.2	-0.2	-0.2	-0.3	0.4	-0.0	-0.4	-0.3	-0.4	-0.6	-0.7	-0.9	0.3
Hearing aid user	1.5	1.7	3.5	1.4	-1.3	-0.8	-1.3	1.4	1.4	1.3	0.0	1.2	1.4	1.9	0.9	1.5	1.5	1.1	0.4	1.2	1.8	1.4	1.6	-1.1
Mother’s age at death	0.1	0.2	1.4	-0.5	0.1	-0.3	0.3	-0.1	0.1	-1.0	0.0	0.0	-0.0	0.1	0.1	-1.2	-0.1	-0.5	-0.0	0.1	0.0	-0.6	0.4	0.2
Financial situation satisfaction	0.5	0.6	3.7	0.5	-0.5	-1.2	-0.5	0.9	0.9	1.9	0.6	0.8	0.5	0.2	0.5	0.3	0.2	0.4	-0.6	-0.8	0.6	0.9	0.6	0.0
Tinnitus: Yes, now most or all of the time	0.7	0.9	4.1	-0.6	0.0	0.1	-0.2	-0.9	-1.6	-0.2	-0.0	-0.2	-0.4	-2.0	-0.2	-1.2	-0.3	-0.8	0.3	-1.3	-1.4	-0.5	-1.9	-0.2
Commuting to job workplace: Public transport	0.5	0.6	3.0	1.2	0.3	0.2	-0.0	0.7	0.8	1.7	-0.4	-0.2	-0.1	1.1	-0.3	0.0	-0.2	1.0	-0.2	0.7	0.9	1.1	1.4	0.5
Eye problems/disorders: Glaucoma	0.4	0.5	1.7	0.2	-1.0	-0.7	-1.1	0.0	-0.5	0.2	0.5	0.8	0.5	-0.8	0.8	0.8	0.7	0.0	1.3	-0.4	0.6	0.2	-0.2	-1.0
Medication: Blood pressure	0.9	1.6	3.1	-1.0	1.5	1.8	1.8	-1.4	-1.1	1.0	-0.7	-1.7	-1.6	-1.1	-1.3	-1.4	-1.7	-0.8	-0.6	-0.7	-1.7	-0.8	-0.7	1.3
Pain type(s) experienced in last month: Hip pain	2.2	2.8	4.7	-1.6	1.8	1.6	1.8	-1.2	-1.6	2.2	-1.6	-1.9	-1.8	-1.6	-1.9	-0.9	-2.0	-1.4	-1.0	-1.6	-1.6	-1.7	-2.1	1.7
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.1	0.4	0.6	0.2	0.3	-0.3	1.0	-0.5	-0.4	-0.5	0.4	0.5	-0.4	-0.2	-0.6	-0.4	-1.5	-1.0	0.5	0.2	1.1	0.8
High cholesterol (Self-reported)	0.1	0.2	1.0	-0.7	0.0	-0.2	-0.2	-0.3	-0.0	0.4	0.4	-0.1	0.1	-0.3	0.2	-0.5	-0.2	-0.4	-0.2	-0.5	-0.4	-0.8	-1.0	0.0
Medication: Bendroflumethiazide	0.1	0.1	0.4	0.4	-0.1	0.2	-0.1	0.6	0.4	-0.3	0.6	-0.3	0.3	0.4	0.4	-0.2	0.1	0.3	-0.1	0.2	0.3	0.3	0.2	-0.2
Medication: Paracetamol	0.7	1.1	3.1	-0.8	-1.7	-1.1	-1.4	-1.1	-0.6	0.1	0.4	1.8	1.1	-1.0	1.2	0.9	1.2	0.1	1.5	-1.1	-0.4	-0.6	-0.7	-1.3
Medication: Lisinopril	0.3	0.4	7.1	0.1	0.2	0.1	0.3	0.3	0.3	2.7	-0.3	-0.2	-0.1	0.3	-0.2	0.5	-0.3	-0.2	-0.0	0.0	0.5	0.1	-0.1	0.6
Medication: Atorvastatin	0.2	0.2	1.3	-0.4	0.6	0.3	0.5	-0.2	-0.6	0.1	-0.2	-0.4	-0.7	-0.4	-0.5	0.0	-0.5	-0.1	-0.5	0.1	-0.4	-0.4	-1.1	0.6
Illnesses of father: High blood pressure	0.4	0.5	2.6	-1.0	0.2	0.3	0.3	-0.5	-0.7	-0.7	-0.7	-0.2	-0.5	-0.9	-0.5	-0.6	-0.4	-1.1	-0.5	-0.9	-0.5	-1.0	-1.6	0.5
Alcohol drinker status: Never	0.2	0.3	2.4	-0.3	0.3	-0.0	0.5	0.4	0.3	-0.0	-1.0	0.1	-0.3	0.6	-0.5	0.6	-0.1	0.1	-1.5	-0.0	0.4	-0.2	0.1	0.8
Ever smoked	0.2	0.3	1.4	0.1	-0.6	-0.4	-0.6	1.2	0.2	0.5	0.9	0.6	0.3	-0.3	0.6	0.7	0.3	-0.1	-0.5	-0.3	0.4	0.5	0.2	-0.4
Basal metabolic rate	0.5	2.8	9.9	-0.7	2.1	3.1	2.4	-1.0	-1.1	-0.8	-0.4	-3.0	-1.6	-1.0	-1.6	-2.4	-1.8	-0.9	-0.6	0.3	-2.4	-0.8	-1.0	1.3
Leg fat percentage (left)	0.2	0.6	3.8	-0.0	-0.6	-0.7	-0.5	1.0	0.7	1.9	1.1	0.6	0.6	0.6	0.9	1.2	0.4	0.8	0.3	0.4	0.7	-0.0	-0.9	-0.2
Arm fat-free mass (left)	0.5	2.4	7.0	-0.6	1.9	2.6	2.1	-1.2	-1.7	-0.5	-0.0	-2.6	-1.5	-1.5	-1.3	-2.3	-1.6	-1.0	0.1	0.4	-2.4	-0.8	-1.6	1.0
Number of operations (self-reported)	4.9	7.3	12.0	1.7	-3.1	-3.4	-3.3	2.8	2.7	-0.3	3.1	3.4	3.5	2.3	3.3	3.4	3.1	2.1	1.8	1.8	2.9	1.5	1.2	-2.7
Average weekly beer plus cider intake	4.5	6.5	12.8	2.5	-2.8	-2.9	-3.0	2.5	2.1	0.5	2.0	2.9	2.8	2.3	2.6	3.6	2.8	2.6	2.2	1.8	2.7	2.4	2.3	-2.6
Irritability	0.6	1.0	4.7	-1.4	0.4	0.3	0.6	-0.8	-0.2	-1.0	-1.0	-0.2	-0.5	-0.8	-0.6	-0.5	-0.7	-1.6	-1.3	-2.2	-0.5	-1.5	-0.8	0.9
Risk taking	0.5	0.7	1.7	-1.0	0.5	0.7	0.3	-0.9	-1.2	-0.6	-1.1	-0.4	-0.8	-1.3	-0.8	-1.2	-0.4	-0.9	0.4	-1.0	-0.5	-1.0	-0.8	0.6
Ever had prostate specific antigen (PSA) test	1.1	1.2	5.0	0.7	-1.1	-0.8	-0.9	0.3	1.3	-2.2	1.4	1.0	1.4	1.1	1.4	0.9	1.2	1.3	-0.4	0.5	1.2	0.6	0.4	-1.0
Fractured/broken bones in last 5 years	0.4	0.5	2.3	-0.2	0.6	0.6	0.6	-0.7	-1.5	0.3	-0.4	-0.5	-0.9	-0.6	-0.7	0.1	-0.2	0.1	0.7	0.9	-1.1	-0.1	-1.0	-0.0
Age started oral contraceptive pill	0.3	0.4	2.0	0.9	-0.2	-0.7	-0.2	0.7	0.4	1.4	0.4	0.4	0.3	0.6	0.3	0.1	0.1	0.9	-0.1	0.9	0.6	0.9	0.2	-0.1
Diastolic blood pressure, automated reading	0.2	0.6	3.2	0.1	-0.5	-1.0	-0.6	0.7	-0.1	1.8	1.6	0.3	0.1	-0.3	0.9	0.1	0.3	0.3	1.7	0.6	-0.3	0.3	-0.2	-0.7
Ever depressed for a whole week	0.6	0.7	2.1	-1.2	0.6	0.4	0.5	-0.9	-0.6	-0.3	-0.8	-0.6	-0.9	-1.1	-0.7	-0.6	-0.8	-1.1	-0.6	-1.5	-0.7	-1.1	-0.9	0.7
Unable to work because of sickness or disability	0.7	1.0	2.3	0.5	-0.8	-1.4	-0.7	0.8	1.5	0.5	0.9	1.1	1.2	1.5	1.0	1.2	0.9	1.2	0.3	1.0	1.1	0.3	0.9	-0.5
Commuting to job workplace: Cycle	1.8	2.2	6.4	2.3	-0.9	-0.9	-1.0	0.6	1.7	0.2	0.8	1.1	1.2	2.0	0.9	1.2	1.3	2.1	0.8	1.4	2.0	2.2	2.5	-1.0
Myopia	0.4	0.6	4.4	0.7	0.9	0.8	0.7	0.2	0.5	2.1	-0.2	-0.7	-0.6	0.5	-0.6	-0.3	-0.8	0.4	-0.5	0.2	0.3	0.7	1.2	1.0
Vascular/heart problems diagnosed by doctor	0.9	2.4	4.2	2.1	-1.8	-1.4	-1.8	0.3	0.5	-0.6	0.7	2.0	1.5	1.1	1.3	2.0	2.0	1.6	1.4	1.3	1.9	2.0	1.6	-1.9
Cholesterol lowering medication	0.7	1.1	4.0	-1.6	1.0	0.7	0.8	-0.6	-0.7	-0.1	-0.2	-1.0	-1.1	-1.0	-0.8	-1.2	-1.0	-0.9	-1.2	-0.9	-1.4	-1.4	-2.0	0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.8	-0.7	0.1	0.2	-0.2	0.5	0.6	0.1	0.1	-0.2	0.0	0.2	0.0	-0.2	-0.3	-0.6	-0.9	-0.5	0.3	-0.6	-0.8	0.3
Pain experienced in last month	4.1	6.9	14.6	3.8	-1.8	-1.8	-2.0	3.1	3.5	-0.2	2.7	1.8	2.9	3.3	2.3	2.2	2.1	2.7	0.7	2.5	3.1	3.5	3.6	-1.8
Supplements: Calcium	0.5	0.5	3.0	-0.8	0.8	0.6	0.9	0.7	0.4	-0.0	-0.4	-0.9	-0.5	0.2	-0.6	0.1	-0.7	-0.0	-1.7	-0.1	-0.5	-0.5	-1.1	0.8
Basal cell carcinoma (self-reported)	0.8	1.0	2.2	-1.1	1.0	0.8	1.1	-1.2	-1.2	-1.4	-0.4	-0.7	-0.9	-1.1	-0.8	-0.9	-1.1	-0.7	-0.6	-0.5	-1.3	-1.2	-1.5	0.8
Heart attack/myocardial infarction (self-reported)	3.5	4.5	7.6	-2.4	1.9	1.8	1.8	-2.8	-2.0	-0.5	-2.6	-1.7	-1.9	-2.1	-2.3	-1.9	-2.0	-2.1	-1.7	-2.5	-2.2	-2.6	-2.5	2.0
Deep venous thrombosis (DVT) (self-reported)	1.8	2.4	4.9	0.8	-1.6	-1.7	-1.6	1.9	1.8	-0.8	2.2	1.5	2.0	1.8	2.0	1.4	1.7	1.4	0.3	1.5	1.5	0.7	1.0	-1.5
Heart disease (siblings)	5.5	6.7	14.0	-3.5	2.6	2.7	2.4	-2.1	-2.1	-0.7	-2.8	-2.8	-2.7	-2.4	-2.6	-2.3	-2.6	-3.0	-1.2	-2.7	-2.8	-3.7	-2.4	2.7
Alcohol drinker status: Previous	0.4	0.4	0.9	-0.9	0.8	0.6	0.9	-0.8	-0.4	0.2	-0.4	-0.6	-0.7	-0.5	-0.6	-0.6	-0.9	-0.2	-0.5	-0.4	-0.7	-0.9	-0.5	0.9
Pack years of smoking	0.7	1.0	4.0	-0.2	-1.4	-2.0	-1.6	0.1	0.5	0.7	1.4	1.6	1.0	0.4	1.5	0.5	1.2	0.2	0.7	0.1	1.2	-0.1	-0.3	-1.0
Impedance of whole body	0.2	0.9	3.8	-0.4	-0.4	-1.0	-0.5	-1.6	-2.0	-0.5	-1.0	1.1	-0.5	-1.8	-0.3	-0.3	0.2	-0.4	1.3	-1.2	-0.4	-0.4	-1.3	-0.4
Leg fat mass (left)	0.1	0.3	1.7	-0.1	0.2	0.5	0.3	0.7	0.4	1.3	0.7	-0.4	0.1	0.4	0.2	0.5	-0.2	0.5	-0.1	0.6	-0.0	-0.1	-1.0	0.2
Arm predicted mass (left)	0.5	2.5	7.8	-0.8	1.9	2.8	2.1	-1.2	-1.6	-0.8	-0.2	-2.6	-1.4	-1.4	-1.4	-2.4	-1.6	-1.0	-0.2	0.3	-2.4	-0.9	-1.6	0.9