TWAS hub - KLHL7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.2150	0.0780	7.1e-04	0.064	NA	0.118	NA	0.128	3.0e-04	NA	1.0e-06	NA	3.7e-07
2	GTEx	Artery Aorta	0.1790	0.0610	2.4e-04	0.100	NA	0.071	NA	0.073	3.7e-06	NA	9.2e-05	NA	7.3e-05
3	GTEx	Cells EBV-transformed lymphocytes	0.2360	0.1050	3.4e-03	0.093	NA	0.026	NA	0.068	5.9e-04	NA	5.0e-02	NA	3.1e-03
4	GTEx	Colon Sigmoid	0.1670	0.0740	4.7e-03	0.000	NA	-0.004	NA	-0.006	3.2e-01	NA	4.7e-01	NA	6.3e-01
5	GTEx	Heart Atrial Appendage	0.1240	0.0400	1.8e-05	0.165	NA	0.148	NA	0.164	7.1e-08	NA	3.5e-07	NA	7.6e-08
6	GTEx	Heart Left Ventricle	0.0861	0.0332	5.6e-04	0.089	NA	0.079	NA	0.087	1.9e-05	NA	5.4e-05	NA	2.3e-05
7	GTEx	Muscle Skeletal	0.0642	0.0243	2.1e-04	0.013	NA	0.008	NA	0.014	1.7e-02	NA	4.6e-02	NA	1.5e-02
8	GTEx	Nerve Tibial	0.1657	0.0697	3.2e-03	0.062	NA	0.084	NA	0.094	3.4e-05	NA	1.4e-06	NA	3.8e-07
9	GTEx	Pancreas	0.1080	0.0500	6.4e-03	0.059	NA	0.043	NA	0.053	1.6e-03	NA	6.6e-03	NA	2.8e-03
10	GTEx	Thyroid	0.1920	0.0570	1.3e-06	0.170	NA	0.112	NA	0.158	5.4e-13	NA	6.4e-09	NA	3.9e-12
11	METSIM	Adipose	0.1088	0.0301	3.2e-10	0.027	0.074	0.108	0.106	0.099	5.2e-05	3.2e-11	8.9e-16	1.5e-15	1.5e-14
12	YFS	Blood	0.0465	0.0142	7.1e-11	0.052	0.036	0.040	0.042	0.049	1.6e-16	7.5e-12	4.6e-13	1.5e-13	1.1e-15
13	TCGA	Lung Squamous Cell Carcinoma	0.0988	0.0501	3.2e-03	-0.002	0.006	0.002	NA	-0.001	8.3e-01	6.7e-02	1.9e-01	NA	4.9e-01
14	TCGA	Stomach Adenocarcinoma	0.0540	0.0370	3.8e-03	0.005	0.035	0.013	NA	0.011	1.3e-01	1.5e-03	3.4e-02	NA	5.2e-02
15	TCGA	Thyroid Carcinoma	0.2470	0.0700	5.4e-14	0.181	0.160	0.174	NA	0.177	2.3e-17	2.4e-15	1.2e-16	NA	6.0e-17

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Breast cancer (self-reported)	9.8	11.7	22.5	-4.1	-4.7	3.2	0.3	3.2	3.6	2.7	-4.0	-3.8	-4.2	-1.5	-4.1	-0.8	-3.2	-4.2
Supplements: Vitamin C	5.4	6.4	9.7	2.5	2.7	-2.7	1.3	-3.1	-3.0	-2.8	2.4	2.9	2.7	-0.4	2.9	-1.4	2.7	2.7
Wears glasses or contact lenses	5.3	6.1	10.8	2.5	3.1	-3.3	-0.3	-2.9	-3.0	-2.5	2.3	2.6	2.7	0.9	2.8	-0.9	2.4	2.6
Triglycerides	5.0	8.2	12.0	-2.7	-3.0	2.9	-1.3	3.5	3.5	3.4	-2.8	-3.2	-3.1	-0.6	-3.2	-1.3	-3.4	-3.1
Shortness of breath walking on level ground	4.8	5.7	11.4	-3.1	-3.4	1.8	-1.0	2.0	2.0	1.8	-2.5	-2.9	-3.1	-0.7	-3.0	-0.8	-2.3	-3.1
Medication: Ventolin 100micrograms inhaler	3.8	4.9	10.0	1.3	2.1	-3.1	1.0	-2.9	-2.9	-3.2	1.1	1.9	1.8	-0.2	2.1	-2.2	3.1	1.7
Reason for reducing amount of alcohol drunk: Health precaution	3.6	4.3	7.1	2.7	1.8	-2.0	0.3	-2.0	-2.1	-2.1	2.4	2.4	2.3	2.3	2.3	-1.5	1.3	2.3
Medication: Co-codamol	3.3	3.9	9.9	1.2	1.8	-1.7	1.4	-2.5	-2.5	-2.6	1.0	2.2	2.0	0.4	2.1	-1.3	3.1	1.9
Severe depression (siblings)	3.3	3.7	6.6	2.0	1.6	-2.0	1.6	-2.5	-2.6	-2.5	1.5	2.1	2.0	0.3	2.1	0.1	2.0	2.0
Frequency of tiredness / lethargy in last 2 weeks	3.3	5.4	11.0	-3.3	-2.5	1.4	-2.9	1.6	1.9	1.7	-3.2	-2.2	-2.6	-2.6	-2.3	1.3	-0.6	-2.7
Mean time to correctly identify matches	3.3	6.3	14.4	1.2	2.9	-3.2	-0.6	-3.0	-3.0	-3.8	1.7	2.8	2.4	0.3	2.7	-1.8	2.8	2.4
Diabetes diagnosed by doctor	3.2	5.3	9.1	-2.9	-3.0	1.5	-2.3	2.1	2.2	2.0	-2.5	-2.5	-2.6	-1.8	-2.5	1.9	-1.3	-2.6
Glaucoma (self-reported)	3.1	3.6	8.2	2.9	2.0	-1.1	0.4	-1.7	-1.8	-1.7	2.9	2.0	2.3	1.8	2.2	0.1	0.9	2.4
Peak expiratory flow (PEF)	3.0	7.0	11.0	2.5	3.0	-2.5	2.7	-2.3	-2.5	-2.7	2.2	3.3	3.3	1.5	3.3	-2.0	2.3	3.2
Illness, injury, bereavement, stress in last 2 years	3.0	3.6	8.5	2.4	2.3	-1.0	1.0	-1.3	-1.7	-1.0	2.5	2.0	2.2	2.9	2.0	-0.8	1.4	2.3
Medication: Lansoprazole	2.9	3.2	6.0	-2.3	-2.5	0.7	-1.4	1.2	1.3	1.4	-2.0	-2.3	-2.2	-0.7	-2.1	1.4	-2.0	-2.2
Forced vital capacity (FVC)	2.8	11.0	27.7	4.0	5.3	-2.3	4.0	-1.9	-2.3	-2.4	3.3	4.0	4.3	0.9	4.0	-1.3	1.9	4.2
Supplements: Fish oil (including cod liver oil)	2.8	3.7	6.2	1.5	2.0	-2.2	-0.3	-2.1	-2.0	-2.2	1.5	2.3	2.1	0.7	2.2	-2.5	1.9	2.0
Vitamin and mineral supplements	2.7	3.7	9.4	-0.9	-2.1	3.1	-0.9	2.6	2.7	2.6	-0.7	-2.1	-1.7	1.1	-1.9	1.0	-1.5	-1.6
Birth weight of first child	2.7	5.0	13.6	3.7	3.0	-1.3	2.3	-1.2	-1.4	-1.9	2.8	2.4	2.7	1.7	2.4	0.8	1.0	2.7
Migraine (self-reported)	2.6	3.2	5.1	-2.1	-2.1	1.7	0.5	1.7	1.8	1.6	-2.2	-2.0	-2.1	-2.3	-2.0	0.3	-0.8	-2.1
Type 2 Diabetes (T2D) (2018)	2.5	4.6	11.9	-3.5	-3.1	0.6	-1.1	1.3	1.5	1.2	-3.1	-2.4	-2.5	-2.4	-2.2	0.7	-0.7	-2.6
Qualifications: O levels/GCSEs or equivalent	2.5	4.0	6.7	-1.4	-2.3	1.9	0.8	2.6	2.4	2.5	-1.9	-2.2	-2.1	-1.2	-2.3	1.1	-2.4	-2.1
Cholesterol lowering medication	2.5	3.6	6.2	-1.3	-1.6	1.6	-2.0	2.1	2.2	2.2	-1.6	-2.1	-2.1	-0.1	-2.1	2.0	-2.5	-1.9
Basal cell carcinoma (self-reported)	2.5	3.0	8.4	-1.1	-1.2	2.0	-1.6	2.6	2.4	2.4	-0.8	-1.6	-1.3	-0.3	-1.6	1.0	-2.9	-1.2
Current tobacco smoking	2.4	4.0	10.0	1.1	1.8	-1.7	1.0	-2.5	-2.3	-3.0	1.1	2.4	2.0	-1.2	2.3	0.1	3.2	1.9
Tinnitus: Yes, but not now, but have in the past	2.4	2.5	4.2	1.4	1.3	-1.8	0.2	-1.9	-2.0	-1.5	1.5	1.8	1.7	1.1	1.7	-2.0	1.4	1.7
Number of incorrect matches in round	2.4	3.9	6.6	-1.4	-2.4	2.4	-1.4	2.2	2.1	2.4	-1.4	-2.4	-2.2	-0.2	-2.3	0.1	-2.6	-2.1
Smoking status: Current	2.4	3.7	7.5	1.5	1.9	-1.4	1.0	-2.2	-2.1	-2.6	1.5	2.4	2.2	-0.7	2.4	0.1	2.7	2.2
Crohns Disease (2012)	2.3	3.7	6.9	-2.3	-2.0	2.6	-0.8	1.8	2.0	1.9	-2.4	-2.2	-2.2	0.0	-2.1	1.3	-1.3	-2.2
Rheumatoid Arthritis	2.3	3.2	6.0	2.1	2.4	-1.8	-0.3	-1.6	-1.6	-1.2	2.4	2.2	2.1	1.3	2.0	-0.4	1.3	2.2
Forced expiratory volume in 1-second (FEV1)	2.3	7.6	16.8	3.4	4.1	-1.9	3.3	-1.5	-1.8	-2.0	2.8	3.4	3.7	1.0	3.4	-1.4	1.6	3.5
Reaction Time	2.2	4.1	12.2	0.7	2.4	-2.8	-0.3	-2.5	-2.5	-3.5	0.9	2.2	1.9	-0.6	2.2	-0.9	2.0	1.9
Diabetes (father)	2.2	2.7	6.3	-2.5	-1.7	1.6	-1.4	1.5	1.7	1.6	-1.7	-1.6	-1.7	-1.4	-1.6	-1.3	-1.4	-1.7
Exposure to tobacco smoke at home	2.2	2.5	4.9	-1.9	-1.2	1.3	-1.6	1.6	1.8	1.5	-2.2	-1.7	-1.6	-0.9	-1.6	-0.3	-1.8	-1.8
Back pain experienced in last month	2.2	3.2	4.8	-1.4	-1.7	1.9	-2.1	1.8	1.8	1.8	-1.5	-2.1	-2.1	-1.2	-2.2	-0.0	-1.9	-2.1
Mineral and other dietary supplements	2.2	3.0	6.1	-1.2	-2.0	2.2	0.5	2.0	2.0	1.9	-1.1	-1.9	-1.7	-0.0	-1.8	2.5	-1.7	-1.6
Age when periods started (menarche)	2.1	4.9	8.0	2.5	1.8	-2.3	2.0	-2.0	-2.2	-1.8	2.4	2.7	2.8	0.5	2.8	-0.4	2.5	2.8
Serious illness, injury or assault to yourself	2.1	2.6	5.7	-2.3	-2.3	0.1	-0.5	0.6	0.8	0.5	-2.4	-2.0	-2.3	-0.8	-2.0	-1.0	-0.5	-2.3
Schizophrenia (2014)	2.0	4.5	12.3	-2.3	-3.5	1.2	-0.5	1.2	1.6	1.1	-2.9	-2.5	-2.8	-1.0	-2.5	-2.0	-1.1	-2.8
Pulse wave Arterial Stiffness index	1.9	2.2	4.7	1.8	2.1	-1.1	-0.3	-1.2	-1.1	-0.9	1.8	1.7	1.7	1.0	1.7	-2.2	0.5	1.8
Overall health rating	1.9	4.1	12.7	-3.5	-2.7	0.4	-1.9	-0.2	0.3	-0.4	-3.6	-1.8	-2.4	-2.2	-1.8	-0.8	0.9	-2.6
Unable to work because of sickness or disability	1.9	2.4	4.0	-2.0	-2.0	0.9	-1.9	0.9	1.0	0.8	-1.8	-1.6	-1.9	-1.7	-1.7	1.6	-0.2	-1.9
Medication: Metformin	1.8	2.6	6.2	-2.5	-1.9	0.3	-2.1	1.0	1.1	1.0	-2.1	-1.6	-1.8	-1.5	-1.7	1.6	-0.6	-1.9
Pulse rate, automated reading	1.8	5.8	9.6	-3.1	-2.5	2.7	-1.3	2.7	2.9	1.7	-2.9	-2.4	-2.6	-2.1	-2.6	0.3	-2.0	-2.6
Commuting to job workplace: Public transport	1.8	2.1	4.2	2.1	1.6	-1.1	1.2	-1.4	-1.4	-1.2	1.7	1.8	1.6	1.4	1.6	0.1	0.7	1.7
Chronic bronchitis/emphysema (father)	1.7	2.0	3.3	-1.1	-1.8	1.6	0.5	1.5	1.6	1.3	-1.0	-1.6	-1.5	-0.2	-1.7	-1.7	-1.4	-1.5
Illnesses of siblings: Diabetes	1.7	2.0	5.2	-2.1	-2.3	-0.1	-1.3	0.8	1.2	0.7	-2.1	-1.4	-1.8	-0.7	-1.6	-0.9	0.3	-1.8
Medication for cholesterol	1.7	2.5	4.7	1.6	1.7	-1.3	0.5	-1.4	-1.5	-1.1	2.1	2.1	2.2	-0.5	2.0	-0.6	1.5	2.1
Eye problems/disorders: Glaucoma	1.7	2.0	6.5	2.5	1.4	-0.8	-1.0	-0.6	-0.8	-0.7	2.5	1.4	1.7	1.3	1.5	0.1	-0.1	1.9
Allergy or Eczema	1.6	4.2	12.1	0.8	1.4	-3.5	1.4	-2.5	-2.3	-2.6	1.2	2.3	2.1	0.4	2.2	-1.3	2.6	2.0
Lung FVC	1.6	7.9	13.8	3.6	2.7	-1.6	3.7	-1.4	-1.5	-1.6	3.2	3.3	3.6	2.4	3.2	-3.3	1.3	3.5
Pulse wave reflection index	1.6	2.0	4.1	2.0	1.4	-1.3	1.1	-1.1	-1.1	-1.4	1.8	1.7	1.8	0.8	1.7	-0.1	0.2	1.8
Medication: Seretide 50 evohaler	1.6	1.8	5.9	-0.8	0.6	-1.5	1.0	-1.9	-1.5	-1.7	-0.9	1.0	0.6	-0.7	0.9	-2.4	2.2	0.4
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	4.8	-1.3	-1.4	2.2	-0.3	1.2	1.3	1.6	-0.9	-1.3	-1.2	-0.7	-1.2	1.2	-1.5	-1.2
Supplements: Calcium	1.6	1.7	4.4	1.1	1.8	-1.2	0.0	-1.3	-1.1	-1.1	1.1	1.4	1.4	0.6	1.4	-2.1	1.5	1.3
Frequency of depressed mood in last 2 weeks	1.5	2.1	9.4	-1.6	-1.3	0.7	-3.1	0.8	1.0	0.7	-1.3	-1.2	-1.6	-2.0	-1.5	0.1	-0.6	-1.6
Diabetes (self-reported)	1.5	2.4	5.3	-1.5	-2.3	0.6	-1.9	1.5	1.4	1.5	-1.2	-1.6	-1.6	-0.7	-1.6	1.9	-1.4	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	1.9	4.2	0.1	1.2	-2.0	-1.0	-1.7	-1.4	-1.3	0.5	1.8	1.6	-0.8	1.8	-0.5	1.9	1.5
Pulse wave peak to peak time	1.5	1.7	4.8	-1.4	-1.5	1.1	0.4	1.2	1.1	0.9	-1.4	-1.5	-1.5	-0.9	-1.5	2.2	-0.4	-1.5
Neck or shoulder pain in last month	1.5	2.1	4.7	-1.5	-2.0	0.8	-2.2	1.4	1.2	0.7	-1.2	-1.8	-1.8	-0.4	-1.8	0.4	-0.8	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	3.0	-1.7	-1.3	1.4	-1.0	1.2	1.3	1.2	-1.7	-1.6	-1.5	-0.5	-1.4	0.4	-1.7	-1.5
Medication: Aspirin	1.5	2.0	6.9	-0.8	-1.3	1.1	-2.6	1.4	1.6	2.1	-0.5	-1.1	-1.1	-0.1	-1.2	1.6	-1.7	-1.1
Risk taking	1.5	2.2	3.6	1.4	1.7	-1.2	1.5	-1.4	-1.4	-1.4	1.6	1.9	1.9	0.9	1.9	-0.4	1.2	1.8
Schizophrenia (2018)	1.4	2.9	7.8	-1.7	-2.8	1.2	-0.6	1.3	1.5	1.1	-2.2	-2.0	-2.1	-1.5	-2.0	-0.8	-1.1	-2.2
Systolic Blood Pressure	1.4	6.8	11.4	-2.8	-2.9	2.8	-1.0	2.7	2.8	3.0	-2.3	-3.4	-3.2	0.6	-3.1	0.2	-2.7	-3.0
Taking other prescription medications	1.4	2.2	5.2	-2.1	-1.4	0.4	-2.3	0.6	0.9	0.8	-1.6	-1.8	-1.9	-1.5	-1.7	-1.2	-0.7	-1.9
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	4.1	-0.7	-0.9	2.0	-1.4	1.4	1.4	1.6	-0.8	-1.4	-1.3	-0.7	-1.3	0.7	-1.4	-1.2
Stomach or abdominal pain in last month	1.4	1.8	7.8	-1.7	-1.0	-1.7	-0.4	-1.2	-1.2	-2.0	-1.5	-0.4	-0.7	-2.8	-0.4	0.1	1.1	-0.8
Birth weight	1.4	3.0	13.7	2.0	3.7	-0.2	1.7	0.2	0.1	0.1	1.9	1.6	2.0	0.1	1.6	2.7	0.5	1.9
Forced vital capacity (FVC), Best measure	1.4	5.1	16.7	3.1	4.1	-0.9	2.8	-0.4	-0.8	-0.5	2.5	2.6	3.1	0.8	2.7	-0.6	0.5	3.0
Age at first live birth	1.4	2.5	5.6	-1.8	-1.9	1.2	1.0	1.9	1.7	1.5	-1.5	-1.6	-1.6	-0.2	-1.7	0.9	-2.4	-1.6
Illnesses of father: Heart disease	1.4	2.0	4.3	2.0	2.1	-0.5	-0.5	-0.6	-0.6	-0.5	1.9	1.5	1.7	1.6	1.6	1.2	0.7	1.8
Financial situation satisfaction	1.4	1.8	5.9	-2.2	-2.0	0.6	0.0	0.3	0.4	-0.0	-2.4	-1.3	-1.7	-1.0	-1.4	0.4	-0.1	-1.8
Schizophrenia vs Biploar Disorder	1.3	1.7	4.7	-1.4	-2.2	0.5	-1.1	0.8	0.8	0.7	-1.5	-1.5	-1.8	-0.2	-1.6	-1.0	-0.8	-1.7
Cardiovascular Disease	1.3	4.4	12.0	-2.8	-2.5	0.9	-0.5	1.1	1.5	1.1	-3.5	-2.5	-2.9	-1.5	-2.5	-0.9	-1.2	-2.9
Systolic blood pressure, automated reading	1.3	3.9	6.8	-2.1	-2.1	1.8	-1.9	2.0	2.0	2.0	-1.4	-2.6	-2.5	0.4	-2.5	-0.6	-1.7	-2.4
Number of live births	1.3	1.9	8.0	-0.3	1.3	-2.2	0.9	-1.8	-1.8	-1.6	-0.3	1.1	0.8	-0.2	1.0	0.2	2.8	0.6
Loud music exposure frequency	1.3	1.4	3.0	0.9	1.6	-1.7	-0.5	-1.5	-1.4	-1.3	0.2	1.3	1.1	-0.6	1.3	-0.0	1.5	1.1
Osteoporosis (self-reported)	1.3	1.7	3.0	1.0	1.4	-1.5	1.4	-1.5	-1.3	-0.9	0.9	1.7	1.6	-0.2	1.7	-0.6	1.1	1.6
Pain type(s) experienced in last month: Hip pain	1.3	1.6	5.0	-2.1	-1.2	0.1	-0.7	0.1	0.4	-0.3	-2.2	-1.3	-1.5	-1.8	-1.2	-0.9	0.5	-1.6
Diabetes (mother)	1.2	1.6	5.7	-1.4	-2.4	1.1	-0.7	1.0	1.3	0.5	-1.4	-1.3	-1.5	-0.9	-1.4	-0.3	0.2	-1.5
Fed-up feelings	1.2	2.2	4.3	-1.9	-2.0	0.6	-1.7	0.9	1.2	0.4	-2.0	-1.6	-2.1	0.2	-1.8	-0.9	-0.2	-2.1
Number of self-reported non-cancer illnesses	1.2	2.0	7.1	-2.7	-1.6	0.2	-0.8	0.0	0.5	0.2	-2.4	-1.3	-1.7	-1.3	-1.3	-1.8	-0.0	-1.8
High cholesterol (Self-reported)	1.2	2.1	3.0	-1.0	-1.7	1.7	-0.6	1.6	1.7	1.7	-1.2	-1.7	-1.7	-0.1	-1.7	1.3	-1.5	-1.6
Ever smoked	1.2	2.2	3.9	1.1	2.0	-1.2	1.2	-1.8	-1.6	-1.4	0.9	1.9	1.8	-0.1	1.9	-0.1	1.5	1.8
High blood pressure	1.1	2.9	5.6	-2.1	-1.7	1.2	-0.9	1.3	1.5	1.4	-2.2	-2.2	-2.4	-0.1	-2.2	-1.1	-1.4	-2.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	9.6	2.5	3.1	-0.9	2.2	-0.5	-0.8	-0.5	1.9	2.3	2.6	0.8	2.3	-0.9	0.5	2.5
Breastfed as a baby	1.1	1.4	5.3	1.2	0.9	-0.9	0.1	-0.9	-0.9	-0.8	1.5	1.1	1.1	1.5	1.1	-2.3	0.7	1.2
Number of full sisters	1.1	1.4	3.5	-0.9	-1.4	1.2	1.9	1.0	1.1	0.7	-1.0	-1.4	-1.3	-0.5	-1.2	1.1	-1.1	-1.2
Knee pain experienced in last month	1.1	1.8	4.7	-2.0	-2.0	0.4	-2.2	0.3	0.4	0.0	-1.5	-1.4	-1.5	-1.6	-1.3	0.3	-0.4	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.2	4.0	1.8	1.6	-1.0	1.6	-0.8	-0.9	-0.8	1.7	2.0	2.0	1.6	1.8	-1.3	1.0	1.9
Vascular/heart problems diagnosed by doctor	1.1	3.1	6.5	2.4	2.0	-0.9	0.4	-1.1	-1.3	-1.3	2.5	2.2	2.5	0.5	2.2	1.0	1.2	2.5
Age at First Birth	1.0	1.4	3.3	-1.5	-1.4	1.2	0.1	1.4	1.2	1.2	-1.1	-1.3	-1.1	-0.5	-1.2	0.5	-1.8	-1.1
Waist Hip Ratio (WHR)	1.0	4.6	8.2	-2.0	-1.8	2.5	-1.8	2.2	2.2	2.5	-1.6	-2.1	-2.0	-2.3	-2.1	2.9	-1.9	-2.0
Ever had hysterectomy (womb removed)	1.0	1.1	2.6	-0.4	-1.0	1.6	-0.4	1.2	1.5	1.6	-0.2	-1.1	-0.9	-0.4	-1.0	0.5	-1.6	-0.8
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	5.8	-1.5	-0.7	0.3	-2.4	0.7	0.6	0.6	-1.2	-0.9	-0.9	-0.9	-0.9	1.1	-0.6	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	6.3	-1.1	-1.0	1.3	-2.5	0.8	1.0	0.7	-1.1	-0.9	-1.2	-1.1	-1.1	0.2	-0.6	-1.2
Qualifications: College or University degree	1.0	3.3	5.8	1.5	2.1	-1.3	2.4	-1.7	-1.7	-2.0	1.5	2.1	2.2	0.6	2.2	-1.3	1.5	2.1
Had major operations	1.0	1.2	3.7	1.2	0.3	-1.9	0.2	-1.5	-1.6	-1.1	1.1	1.3	0.9	0.4	1.0	-0.3	0.4	1.0
Age at last live birth	1.0	1.4	2.3	-1.4	-1.2	1.2	1.3	1.5	1.2	1.4	-1.1	-1.0	-1.0	-0.6	-1.1	1.5	-1.3	-1.0
Leg pain on walking	1.0	1.3	3.6	-1.4	-1.9	1.0	-1.1	0.7	0.7	0.4	-1.4	-1.1	-1.3	-0.5	-1.2	-0.9	-1.3	-1.3
Medication: Aspirin	1.0	1.3	7.0	-0.4	-0.9	0.5	-2.7	0.9	1.0	1.9	-0.2	-0.7	-0.7	-0.5	-0.8	1.6	-1.3	-0.7
Medication: Gliclazide	1.0	1.1	3.1	-1.5	-1.2	-0.1	-1.2	0.2	0.4	0.2	-1.4	-1.2	-1.2	-1.8	-1.1	0.9	0.2	-1.3
Average weekly champagne plus white wine intake	1.0	1.4	4.0	2.0	1.7	0.4	-1.4	0.4	0.2	0.5	1.9	1.0	1.4	1.2	1.1	-0.1	-0.9	1.4
Medication: Blood pressure	1.0	1.9	4.3	-2.1	-1.4	0.6	0.1	0.6	0.9	0.7	-2.0	-1.7	-2.1	0.3	-1.8	0.8	-0.2	-2.0
Medication: Atorvastatin	1.0	1.3	3.2	0.1	-0.8	1.3	-1.3	1.1	1.2	1.6	0.0	-1.0	-0.9	0.7	-0.9	1.8	-1.8	-0.7
Alcohol drinker status: Never	1.0	1.2	2.5	1.0	0.5	-1.3	0.1	-1.4	-1.6	-1.6	0.7	1.3	1.1	-0.5	1.1	0.3	1.3	1.0
Bipolar Disorder or Schizophrenia	0.9	2.3	7.4	-1.7	-2.7	0.7	0.2	0.8	1.1	0.3	-2.1	-1.7	-1.9	-1.2	-1.8	-1.1	-0.5	-2.0
Depressed Affect (Nagel 2018)	0.9	1.8	6.5	-0.3	0.1	-2.5	-1.7	-2.0	-1.7	-2.1	-0.5	0.6	-0.1	-0.6	0.3	-1.3	1.8	-0.1
Smoking Status	0.9	2.2	5.0	0.3	1.7	-1.6	0.1	-1.8	-1.7	-2.0	0.3	1.7	1.4	-1.3	1.6	0.8	2.2	1.3
Average weekly spirits intake	0.9	1.1	2.6	0.9	0.9	-1.1	1.6	-1.5	-1.2	-0.9	0.4	1.0	0.9	-0.1	1.1	-0.7	1.4	0.9
Supplements: Zinc	0.9	1.0	2.1	0.4	1.4	-1.4	-0.3	-0.9	-0.9	-1.1	0.2	1.0	0.9	-1.4	1.0	0.9	1.0	0.9
Medication: Atenolol	0.9	1.1	4.8	-1.6	-0.9	0.3	-2.2	0.7	0.8	1.2	-0.8	-1.0	-1.1	0.0	-1.0	0.5	-0.4	-1.1
Medication: Simvastatin	0.9	1.3	3.6	-1.4	-1.9	0.7	-0.4	0.7	0.8	0.9	-1.7	-1.1	-1.4	-1.0	-1.2	1.0	-0.4	-1.4
Father’s age at death	0.9	1.2	2.9	-0.7	-0.9	1.1	-0.1	1.3	1.3	1.6	-1.0	-1.1	-0.9	-1.2	-1.0	0.3	-1.7	-1.0
Noisy workplace	0.9	1.1	2.5	0.7	0.0	-1.4	0.2	-1.4	-1.3	-1.6	0.8	1.1	0.8	0.4	1.0	-1.3	1.2	0.9
Ever highly irritable/argumentative for 2 days	0.9	1.0	4.1	-1.4	-2.0	-0.2	-0.3	0.3	0.3	-0.1	-1.3	-1.1	-1.4	0.4	-1.2	-0.1	-0.9	-1.4
Leg fat percentage (left)	0.9	3.2	8.4	-2.9	-1.9	0.1	-2.5	0.2	0.5	-0.2	-2.7	-1.4	-2.0	-2.4	-1.5	-1.9	0.2	-2.1
Irritability	0.9	1.6	5.5	-2.1	-1.3	0.8	-0.6	0.0	0.5	-0.1	-2.3	-0.5	-1.1	-2.2	-0.7	1.1	1.1	-1.2
Heart disease (siblings)	0.9	1.1	3.3	-1.7	-1.2	0.1	-1.8	0.7	0.8	0.5	-1.3	-0.9	-1.2	-1.1	-1.0	-0.3	-0.0	-1.2
Lupus	0.8	1.2	2.9	-1.3	-0.6	1.5	-0.6	1.1	1.3	1.4	-1.2	-1.1	-1.0	-0.6	-1.1	1.7	-0.1	-1.1
Primary Biliary Cirrhosis	0.8	1.1	2.0	1.4	1.1	-1.1	-0.7	-0.8	-0.8	-0.6	1.2	1.1	1.2	0.1	1.1	-1.4	1.2	1.2
Hand grip strength (right)	0.8	2.2	7.6	1.3	0.4	2.7	0.5	2.6	2.2	1.8	0.7	-0.8	-0.1	0.7	-0.7	0.7	-2.3	-0.1
Maternal smoking around birth	0.8	1.2	3.1	-1.0	-1.1	1.1	-1.8	1.0	0.9	0.5	-0.9	-1.2	-1.3	-1.3	-1.2	-0.9	-0.4	-1.2
Qualifications: CSEs or equivalent	0.8	1.1	4.7	-1.4	-1.3	-0.7	2.2	-0.5	-0.5	-0.9	-1.9	-0.1	-0.5	-1.2	-0.3	-0.4	0.8	-0.7
Waist circumference	0.8	3.1	9.5	-2.9	-0.7	0.8	-1.6	0.7	0.9	0.4	-3.1	-1.6	-2.0	-2.9	-1.7	0.1	-0.1	-2.2
Lung cancer (father)	0.8	0.9	2.1	1.4	0.8	-0.5	1.1	-0.9	-1.0	-0.8	1.3	1.1	1.1	0.7	1.1	0.4	0.7	1.1
Health satisfaction	0.8	1.1	3.1	-1.6	-1.1	0.7	-1.0	0.3	0.4	0.4	-1.8	-1.0	-1.2	-1.5	-1.0	-0.0	0.2	-1.3
Medication: Allopurinol	0.8	1.0	2.8	-1.7	-1.4	1.0	0.5	0.5	0.7	-0.3	-1.5	-1.1	-1.2	-0.7	-1.1	-0.0	-0.1	-1.3
Commuting to job workplace: Walk	0.8	0.8	2.8	-0.5	-0.3	-1.2	-0.4	-1.1	-0.8	-1.5	-1.1	0.5	-0.0	-1.7	0.3	0.6	1.3	-0.1
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.1	1.0	0.2	-1.4	0.7	-1.2	-1.3	-1.4	0.9	1.0	0.9	0.5	0.9	0.1	0.6	0.9
Height	0.7	12.8	92.2	5.5	9.6	0.8	-0.8	1.0	0.5	1.4	4.4	2.3	3.5	2.2	2.7	1.3	-1.4	3.7
Hand grip strength (left)	0.7	2.0	6.7	1.2	0.8	2.6	0.1	2.4	2.1	2.0	0.8	-0.5	0.2	-0.3	-0.3	1.7	-1.6	0.2
Medication for hormone replacement therapy	0.7	0.8	4.7	0.5	0.5	-0.5	0.6	-0.7	-0.8	-0.7	0.2	0.5	0.6	1.5	0.7	-2.2	0.3	0.6
Medication: Levothyroxine sodium	0.7	1.3	3.3	-1.5	-0.9	-0.1	-1.8	0.4	0.8	0.6	-1.5	-1.1	-1.1	-1.6	-0.9	-1.3	-0.7	-1.2
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.4	0.9	0.9	-0.6	1.9	-0.3	-0.5	-0.9	1.1	1.1	1.1	0.8	1.0	0.6	0.3	1.2
Pulse rate	0.7	1.2	4.5	-2.1	-1.2	0.1	0.2	0.2	0.5	-0.2	-2.0	-0.9	-1.4	-1.2	-1.1	-0.6	0.1	-1.4
Standing height	0.7	7.2	48.0	4.0	6.9	0.3	1.3	0.8	0.2	1.0	2.8	1.6	2.6	0.3	2.0	3.4	-0.9	2.7
Chronic bronchitis/emphysema (mother)	0.7	0.8	5.6	-0.4	0.1	-1.1	-2.4	-0.6	-0.5	-1.1	-0.2	-0.3	-0.3	-1.5	-0.2	0.7	0.7	-0.3
Leg fat percentage (right)	0.7	2.6	6.7	-2.5	-1.8	0.2	-2.6	0.3	0.5	-0.0	-2.3	-1.4	-1.8	-2.0	-1.5	-1.7	-0.1	-1.9
Hypertension (Self-reported)	0.7	1.9	3.9	-1.7	-1.3	0.7	-0.8	0.7	1.0	1.0	-1.9	-1.7	-2.0	-0.2	-1.7	-1.5	-1.0	-1.9
Mood swings	0.7	1.2	2.5	-1.4	-0.6	-1.6	-1.0	-1.5	-1.2	-1.6	-1.2	0.2	-0.4	-1.3	0.0	-1.1	1.3	-0.5
Osteoarthritis (self-reported)	0.7	0.9	5.2	-0.5	0.1	-1.2	-1.6	-0.8	-0.7	-0.8	-0.7	-0.1	-0.3	-1.3	-0.2	-2.3	0.8	-0.4
Medication: Paracetamol	0.7	1.0	8.9	-1.5	-0.9	-0.9	-0.9	-0.3	-0.1	0.1	-0.9	-0.1	-0.5	-0.2	-0.3	-3.0	0.4	-0.5
Number of operations (self-reported)	0.7	1.0	2.2	1.3	0.1	-1.1	-0.5	-1.5	-1.4	-0.7	1.4	1.2	1.0	0.6	1.1	-0.7	0.3	1.1
Depression (Nagel 2018)	0.6	0.9	5.4	-0.7	-0.7	0.3	-2.3	0.1	0.3	-0.0	-0.8	-0.6	-1.0	-1.8	-0.8	0.4	-0.4	-0.9
Neuroticism (Nagel 2018)	0.6	1.5	4.7	-0.7	-0.2	-2.2	-1.0	-1.9	-1.6	-2.1	-0.6	0.6	-0.0	-0.6	0.3	-1.0	1.8	-0.1
Breast Cancer	0.6	1.5	3.3	-1.7	-0.9	0.8	-0.6	1.1	1.2	1.4	-1.8	-1.5	-1.4	-1.4	-1.3	-0.2	-0.8	-1.5
HbA1C	0.6	0.7	2.0	-0.7	-0.2	0.6	-0.3	0.9	1.0	0.9	-0.6	-0.9	-1.1	-0.9	-1.0	0.1	-1.4	-1.0
Heel T-Score	0.6	4.7	9.4	-0.4	-3.0	2.6	-1.0	2.8	2.5	3.1	-0.8	-2.5	-2.2	0.3	-2.5	-0.4	-2.9	-2.0
Sensitivity / hurt feelings	0.6	1.0	3.2	-0.2	0.2	-1.4	-0.7	-1.6	-1.3	-1.8	0.0	1.0	0.5	-0.4	0.8	0.1	1.7	0.5
Townsend deprivation index at recruitment	0.6	0.8	1.9	-1.3	-1.1	-0.2	0.8	-0.7	-0.4	-0.8	-1.3	-0.3	-0.7	-1.2	-0.4	1.4	0.9	-0.7
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.9	0.3	0.8	-2.2	0.9	-1.2	-1.1	-1.1	0.6	1.1	1.1	0.3	1.1	-1.0	1.4	1.0
Sitting height	0.6	4.4	26.4	2.9	5.1	0.9	0.8	1.0	0.6	0.9	2.4	1.1	2.0	1.1	1.4	3.0	-1.0	2.0
Had menopause	0.6	0.7	4.5	0.4	0.6	-0.8	-1.4	-0.6	-0.5	-0.3	0.6	0.2	0.3	1.2	0.3	-2.1	0.0	0.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.1	-1.5	-1.1	-0.1	0.3	-0.7	-0.6	-1.1	-1.4	-0.4	-0.8	-0.6	-0.5	-1.3	0.1	-0.9
Pain all over the body in last month	0.6	0.6	1.7	1.0	1.3	0.7	0.1	0.2	0.3	0.5	0.8	0.7	0.9	1.3	0.8	-0.1	-0.5	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.5	-0.7	-1.1	0.5	-0.3	0.9	1.0	0.8	-0.5	-0.7	-0.7	-1.0	-0.8	0.8	-1.2	-0.7
Length of working week for main job	0.6	0.7	4.9	0.2	0.7	0.2	-2.2	0.1	0.1	0.5	0.4	0.4	0.5	-1.5	0.4	0.9	0.0	0.5
Worry too long after embarrassment	0.6	0.9	2.0	-1.1	-0.5	-0.9	1.2	-1.0	-0.9	-1.4	-1.3	-0.0	-0.3	-1.4	-0.0	-1.0	1.3	-0.5
Emphysema/chronic bronchitis	0.6	0.7	1.0	1.0	0.7	-1.0	0.8	-0.9	-0.6	-0.6	0.9	1.0	0.9	0.4	0.9	-0.6	0.8	0.9
Medication: Ibuprofen	0.6	0.7	6.3	-0.0	-0.0	-0.6	0.5	-0.6	-0.6	-0.8	-0.7	0.6	0.4	-0.1	0.5	-2.5	1.1	0.2
Comparative height size at age 10	0.6	3.1	25.0	2.5	5.0	0.7	-0.1	1.2	0.8	1.2	1.6	0.3	1.1	0.6	0.6	1.5	-1.8	1.1
Long-standing illness, disability or infirmity	0.6	1.0	2.8	-1.5	-0.3	0.8	-0.7	0.4	0.8	0.6	-1.6	-0.9	-1.0	-1.7	-0.8	0.8	-0.9	-1.0
Friendships satisfaction	0.6	0.8	1.7	-1.3	-0.4	0.9	-1.0	0.6	0.8	0.1	-1.3	-0.8	-1.0	-1.2	-0.9	-0.3	-0.8	-1.0
Guilty feelings	0.6	0.9	2.7	-1.3	-0.4	-1.6	-1.1	-1.0	-0.9	-1.2	-1.0	-0.2	-0.6	-0.1	-0.3	-1.4	1.1	-0.7
Hearing aid user	0.6	0.6	2.7	1.1	-0.4	0.2	1.6	-0.1	0.1	0.5	0.9	0.1	0.0	1.5	0.0	-0.2	-1.4	0.2
Tinnitus: Yes, now most or all of the time	0.6	0.8	2.7	0.8	1.2	-0.3	-1.0	0.0	-0.1	0.4	1.2	0.5	0.7	1.6	0.6	-1.2	-0.7	0.8
Medication: Lisinopril	0.6	0.8	3.5	-1.9	-1.1	0.2	-0.4	0.3	0.3	0.5	-1.4	-0.9	-1.1	-0.5	-0.9	-0.5	0.1	-1.1
Age started oral contraceptive pill	0.6	0.8	1.8	-1.0	-0.4	-0.5	-1.0	1.0	1.1	0.8	-0.8	-1.0	-1.0	-0.5	-1.0	0.2	-1.4	-1.0
Pack years of smoking	0.6	0.9	2.5	-1.2	-1.5	0.5	-0.7	0.4	0.6	0.2	-1.3	-0.9	-1.0	-1.6	-0.8	0.1	-0.8	-1.0
Multivitamins +/- minerals	0.5	0.6	1.7	0.2	1.2	-1.3	0.7	-0.9	-1.0	-0.7	-0.1	0.7	0.5	-0.9	0.6	0.5	-0.3	0.5
Supplements: Glucosamine	0.5	0.6	2.0	0.9	1.4	-0.7	-0.2	-0.5	-0.8	-0.2	0.9	0.8	0.9	-0.5	0.8	0.9	0.5	0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.9	-0.1	-0.6	-0.8	0.8	-0.8	-0.6	-1.7	-0.2	0.1	-0.1	-0.3	0.1	-1.6	0.1	-0.1
Body mass index (BMI)	0.5	2.0	6.8	-2.5	-1.0	-0.5	-1.0	-0.8	-0.5	-1.3	-2.6	-0.5	-1.3	-2.0	-0.7	-1.6	1.2	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.4	-0.7	-1.3	0.8	-1.5	0.5	0.6	0.5	-0.8	-0.9	-1.2	-0.8	-1.1	-0.2	-0.5	-1.1
Hair/balding pattern: Pattern 2	0.5	0.7	3.9	0.7	-0.0	-0.0	-0.1	-0.7	-0.6	-0.9	0.8	0.9	0.7	0.4	0.7	2.0	1.1	0.7
Financial difficulties in last 2 years	0.5	0.7	1.4	-1.0	-1.2	1.0	-0.5	0.9	1.1	0.4	-0.7	-0.8	-0.9	-0.6	-0.9	0.5	-0.9	-0.9
Arm fat percentage (right)	0.5	1.8	5.2	-2.0	-0.8	-0.8	-2.0	-0.9	-0.5	-1.1	-1.9	-0.4	-1.0	-2.3	-0.5	-1.6	1.1	-1.1
Hair/balding pattern: Pattern 3	0.5	0.7	1.4	-1.0	-1.2	0.8	0.6	0.7	0.9	0.8	-1.0	-0.9	-0.8	0.7	-0.8	-0.4	-1.0	-0.8
Happiness	0.5	0.6	1.9	-0.8	-0.7	-0.3	-0.7	-0.1	-0.2	-0.8	-1.1	-0.5	-1.0	0.4	-0.8	-1.4	-0.2	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.7	-1.0	-1.1	0.1	0.4	0.2	0.2	-0.1	-1.6	-0.4	-0.7	-0.8	-0.5	-1.2	0.4	-0.8
Illnesses of mother	0.5	0.6	2.7	-0.6	-0.3	1.6	-0.0	1.2	0.9	1.2	-0.4	-0.5	-0.4	0.7	-0.5	-0.3	-0.9	-0.4
Body fat percentage	0.5	1.9	5.8	-2.2	-0.6	-0.7	-1.9	-0.8	-0.4	-1.0	-2.1	-0.6	-1.1	-2.4	-0.6	-1.7	1.0	-1.2
Exposure to tobacco smoke outside home	0.5	0.7	5.6	-1.2	-1.0	-0.2	-0.0	-0.1	0.0	-0.6	-1.1	-0.3	-0.5	-2.4	-0.4	0.1	0.2	-0.6
Chest pain or discomfort	0.5	0.8	7.0	0.2	1.3	-0.6	-2.6	-0.6	-0.4	0.2	0.2	0.2	0.3	-0.7	0.4	1.0	0.4	0.3
Smoking status: Previous	0.5	0.7	1.6	-1.2	-0.2	0.2	-0.3	0.7	0.8	1.2	-1.3	-0.8	-0.8	-1.0	-0.7	0.6	-1.2	-0.8
Arm fat percentage (left)	0.5	2.0	5.0	-2.2	-0.8	-0.8	-1.5	-1.0	-0.6	-1.3	-2.2	-0.4	-1.1	-2.2	-0.5	-1.9	1.3	-1.2
Loneliness, isolation	0.5	0.7	1.8	0.4	-0.1	-1.1	-0.5	-1.3	-1.3	-1.4	0.1	0.7	0.3	-0.6	0.5	-1.2	1.0	0.3
Miserableness	0.5	0.8	2.5	-1.0	-0.2	-1.6	-0.8	-1.2	-1.0	-1.2	-1.2	0.1	-0.4	-0.8	-0.0	-0.0	1.3	-0.5
Medication: Bendroflumethiazide	0.5	0.7	2.0	-1.4	-0.3	-0.1	-0.7	-0.1	0.0	-0.6	-1.4	-0.7	-1.0	-1.4	-0.8	0.4	0.0	-1.1
Myopia	0.5	0.7	2.9	-0.4	-0.4	-0.8	1.7	-0.9	-0.9	-1.1	-0.3	0.1	-0.2	1.1	0.0	-1.1	1.1	-0.2
Worry (Nagel 2018)	0.4	0.9	4.1	0.3	0.3	-2.0	-0.8	-1.3	-1.4	-1.3	0.5	0.8	0.6	0.6	0.7	-0.6	0.8	0.6
Alzheimer’s Disease (in mother)	0.4	0.5	1.3	-1.0	-0.7	-0.0	-1.1	0.3	0.5	0.8	-0.8	-0.5	-0.7	-1.2	-0.6	-0.7	-0.4	-0.7
Prostate Cancer	0.4	0.5	3.0	0.5	0.4	-0.3	0.1	-0.4	-0.3	-0.6	0.3	0.7	0.6	-0.8	0.6	1.7	1.0	0.6
Neuroticism (2016)	0.4	0.6	2.1	-1.0	-1.5	0.0	-0.2	0.5	0.7	0.1	-1.0	-0.6	-1.1	-0.0	-0.9	-0.9	-0.3	-1.0
Type 2 Diabetes (T2D) (2012)	0.4	0.4	4.6	-0.3	-0.2	-0.5	-2.1	0.5	0.4	0.3	0.1	-0.1	0.1	-0.5	-0.0	-0.6	0.0	0.1
Neuroticism	0.4	1.0	3.8	-0.8	-0.0	-1.7	-1.9	-1.2	-1.1	-1.4	-0.5	0.6	0.0	-0.9	0.3	0.2	1.4	-0.0
Number of treatments/medications taken	0.4	0.8	2.2	-1.2	-0.9	-0.5	-1.1	-0.1	0.1	0.1	-1.2	-0.7	-1.0	-1.2	-0.7	-1.5	-0.2	-1.0
Pack years adult smoking proportion	0.4	0.7	1.8	-1.0	-1.4	0.5	-0.7	0.4	0.5	-0.0	-1.1	-0.7	-0.9	-1.3	-0.7	0.2	-0.6	-0.9
Trunk fat percentage	0.4	1.7	5.7	-1.9	0.1	-1.1	-1.4	-1.1	-0.8	-1.2	-1.9	-0.1	-0.6	-2.4	-0.2	-1.7	1.4	-0.8
Qualifications: None of the above	0.4	0.9	7.6	0.3	0.8	-0.3	-2.8	-0.5	-0.5	0.0	0.9	0.4	0.5	0.8	0.4	-1.1	0.6	0.5
Mouth/teeth dental problems	0.4	0.6	1.7	0.2	-0.8	1.0	1.3	1.0	0.8	0.2	-0.1	-0.6	-0.5	-0.1	-0.7	0.8	-1.2	-0.5
Falls in the last year	0.4	0.6	2.6	-0.7	-0.7	-0.1	-1.6	0.4	0.3	0.5	-0.4	-0.5	-0.6	0.5	-0.5	-1.6	-0.7	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.8	-0.2	1.2	-1.7	0.5	-1.2	-1.1	-1.4	-0.5	0.8	0.6	-1.0	0.9	-1.0	0.9	0.5
Asthma	0.4	0.8	2.9	-1.4	-1.1	-0.4	-0.6	0.2	0.4	0.5	-0.9	-0.8	-1.0	-0.1	-0.9	-1.7	0.3	-1.0
Number of full brothers	0.4	0.5	1.2	-0.3	0.7	-1.0	-0.4	-0.9	-0.6	-1.0	-0.2	0.6	0.3	-0.8	0.5	-0.9	1.1	0.3
Number of children fathered	0.4	0.5	1.4	-0.4	-0.7	1.2	-0.7	0.8	0.9	0.4	-0.6	-0.7	-0.7	-0.2	-0.7	-0.3	-0.3	-0.7
Eye problems/disorders: None of the above	0.4	0.5	2.0	-0.7	-0.8	0.7	0.4	0.3	0.7	0.6	-0.6	-0.5	-0.8	0.6	-0.7	-1.4	-0.4	-0.7
Heart disease (mother)	0.4	0.5	1.2	-0.4	-0.6	1.1	-0.8	0.9	1.0	0.9	-0.4	-0.6	-0.6	-0.4	-0.6	0.7	-0.6	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.4	0.9	0.2	0.4	-0.5	0.4	0.2	1.2	1.0	0.4	0.6	0.9	0.4	-0.6	-1.0	0.7
Leg fat mass (right)	0.4	1.4	5.0	-1.9	-0.4	0.4	-1.4	0.2	0.4	-0.2	-2.0	-0.9	-1.2	-2.2	-0.9	-0.7	0.3	-1.3
Family relationship satisfaction	0.4	0.5	3.4	-0.3	-0.1	0.1	-1.5	-0.0	-0.1	-0.7	-0.4	0.1	-0.1	-1.8	0.1	0.8	0.2	-0.1
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.4	-0.1	1.2	-0.2	1.1	-0.8	-0.8	-0.2	0.3	0.6	0.7	-0.2	0.8	-0.3	0.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	3.5	0.8	1.9	1.2	1.4	0.8	0.7	1.0	0.4	0.4	0.7	0.5	0.5	1.3	-0.6	0.7
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.3	-0.6	-1.3	-0.3	-0.3	0.1	0.0	0.1	-0.2	-0.2	-0.4	-1.3	-0.3	1.5	-0.4	-0.3
Qualifications: nursing, teaching	0.4	0.7	4.2	-0.5	0.1	-0.9	1.2	-0.9	-0.9	-0.9	-0.8	0.1	0.1	-2.0	0.3	0.2	0.2	0.0
Eye problems/disorders: Cataract	0.4	0.5	3.1	-0.5	-0.2	0.6	0.3	0.6	0.4	0.3	-0.6	-0.5	-0.4	-1.2	-0.5	1.8	0.3	-0.4
Ever taken oral contraceptive pill	0.4	0.4	2.8	-1.7	-0.5	0.2	-0.4	0.4	0.5	0.6	-1.0	-0.4	-0.7	0.0	-0.6	0.2	-0.0	-0.7
Illnesses of father: High blood pressure	0.4	0.5	1.3	-1.2	-0.9	0.9	-0.3	0.6	0.9	0.4	-0.9	-0.5	-0.6	-0.8	-0.5	0.3	-0.4	-0.6
Commuting to job workplace: Cycle	0.4	0.5	4.1	0.1	0.1	-0.7	0.6	-0.6	-0.6	-0.8	-0.1	0.4	0.1	-1.0	0.2	2.0	0.7	0.1
Leg fat mass (left)	0.4	1.5	5.2	-2.0	-0.3	0.3	-1.3	0.1	0.3	-0.3	-2.2	-0.8	-1.2	-2.3	-0.9	-0.9	0.4	-1.4
Bipolar Disorder (2018)	0.3	0.4	1.6	-0.6	-0.8	-0.4	1.3	-0.3	-0.2	-1.0	-0.6	-0.2	-0.4	-0.5	-0.3	-0.6	0.6	-0.4
Alzheimer’s Disease (including proxy)	0.3	0.5	1.8	-0.3	-0.2	-1.3	0.2	-1.0	-0.7	-0.9	-0.4	0.6	0.1	-1.3	0.3	-0.2	0.8	0.1
Crohns Disease (2017)	0.3	0.6	2.5	-0.7	-0.7	0.9	0.8	0.1	0.3	0.7	-0.7	-0.7	-0.7	1.6	-0.6	-0.2	-0.8	-0.7
Major Depression (MDD)	0.3	0.4	0.7	0.8	0.3	-0.9	0.7	-0.8	-0.7	-0.4	0.7	0.7	0.6	0.1	0.6	-0.7	0.1	0.6
Body Mass Index (BMI) (2010)	0.3	0.5	1.3	-0.6	-0.2	-1.1	0.7	-0.9	-0.8	-1.1	-0.7	0.0	-0.2	-1.1	-0.0	0.0	0.9	-0.3
Coronary Artery Disease (CAD)	0.3	0.4	2.1	-0.5	0.1	-1.0	-1.5	-0.6	-0.6	-0.3	0.2	-0.3	-0.3	0.3	-0.2	0.7	0.5	-0.2
Mean Putamen Volume	0.3	0.3	1.1	-0.5	-0.8	-0.3	1.0	-0.2	-0.2	-0.6	-0.7	-0.2	-0.5	0.3	-0.4	-0.9	-0.0	-0.5
Fasting Glucose	0.3	0.4	3.0	-0.1	-0.1	0.9	1.7	0.4	0.4	0.4	-0.6	-0.1	-0.1	0.5	-0.1	0.7	-0.9	-0.1
HDL Cholesterol	0.3	0.6	2.4	-0.4	-0.7	0.4	1.3	-0.3	-0.5	-0.7	-0.3	-0.3	-0.3	-1.5	-0.3	1.5	0.6	-0.3
Ulcerative Colitis	0.3	0.5	1.5	0.8	0.8	0.8	-0.7	0.5	0.4	0.3	0.6	0.5	0.7	0.8	0.5	1.2	-0.6	0.7
BMI	0.3	2.0	5.1	-2.0	-0.5	-1.2	0.5	-1.6	-1.3	-2.2	-2.2	0.2	-0.6	-1.9	-0.1	-1.0	2.0	-0.8
Lung FEV1/FVC ratio	0.3	1.7	3.5	1.4	1.0	-1.4	-0.4	-1.1	-1.1	-1.1	1.8	1.9	1.7	1.0	1.6	-0.3	0.8	1.7
Hair Pigment	0.3	8.0	12.7	2.6	1.7	-3.2	1.7	-3.3	-3.3	-3.1	2.7	2.8	2.5	3.6	2.6	-3.1	2.9	2.6
Ever used hormone-replacement therapy (HRT)	0.3	0.4	3.9	-0.6	0.3	-0.1	-0.5	-0.5	-0.4	-0.1	-0.6	0.2	0.2	0.6	0.3	-2.0	0.5	0.1
Impedance of leg (right)	0.3	1.6	4.8	0.8	-1.1	0.9	-2.0	1.6	1.4	2.2	1.1	-1.0	-0.3	0.7	-0.7	0.5	-2.0	-0.2
Leg fat-free mass (left)	0.3	1.4	10.4	0.4	3.2	0.0	1.4	-0.4	-0.5	-0.9	-0.4	0.8	0.7	-1.5	0.8	1.2	0.9	0.6
Impedance of leg (left)	0.3	1.7	5.0	0.1	-1.6	1.0	-1.9	1.8	1.6	2.2	0.4	-1.3	-0.8	0.2	-1.1	0.2	-1.9	-0.7
Trunk fat mass	0.3	1.2	5.2	-1.4	1.1	-0.8	-1.0	-0.8	-0.6	-1.1	-1.6	0.0	-0.3	-2.3	0.0	-1.1	1.2	-0.5
Hearing difficulty/problems with background noise	0.3	0.4	1.6	-0.4	-0.6	-1.3	-0.1	-0.8	-0.7	-0.8	-0.6	-0.1	-0.5	-0.3	-0.3	-1.0	0.5	-0.5
Illnesses of siblings	0.3	0.4	1.9	0.8	0.0	0.1	0.9	0.3	0.0	0.3	1.0	-0.2	0.3	1.4	0.0	1.0	-0.7	0.4
Neuroticism score	0.3	0.7	2.3	-0.6	-0.1	-1.5	-0.9	-1.1	-1.1	-1.5	-0.6	0.5	-0.1	-0.3	0.2	-0.8	1.2	-0.1
Trunk fat-free mass	0.3	1.8	15.1	1.8	3.9	0.7	1.1	0.4	0.2	0.0	0.7	0.7	1.0	-0.2	0.8	1.8	-0.2	1.0
Time employed in main current job	0.3	0.4	1.9	-0.1	0.9	-0.5	-0.3	-0.4	-0.4	-0.5	0.6	0.5	0.5	-0.2	0.4	-1.4	1.1	0.4
Mouth/teeth dental problems: Dentures	0.3	0.5	3.6	-0.7	0.1	-0.6	-1.9	-0.2	-0.1	-0.1	-0.7	-0.5	-0.5	-1.0	-0.3	0.6	0.8	-0.5
Depression (self-reported)	0.3	0.4	2.0	-1.1	-1.0	-0.5	-1.4	-0.3	-0.4	-0.4	-0.4	-0.2	-0.5	-0.3	-0.3	-0.5	-0.4	-0.5
Arm fat mass (right)	0.3	1.2	4.2	-1.6	0.3	-0.7	-1.1	-0.7	-0.5	-1.2	-1.8	-0.2	-0.7	-2.0	-0.3	-1.4	1.1	-0.8
Trunk predicted mass	0.3	1.8	14.9	1.9	3.9	0.6	1.1	0.4	0.1	-0.0	0.8	0.7	1.1	-0.2	0.8	1.9	-0.2	1.0
Tense / ‘highly strung’	0.3	0.4	1.1	-0.8	-0.6	-0.3	-0.3	-0.8	-0.6	-1.0	-0.5	0.6	0.3	-1.1	0.5	-0.9	0.4	0.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.3	-0.1	0.9	-0.2	-0.7	-0.9	-0.6	0.3	0.1	0.7	0.6	0.2	0.8	-1.1	0.9	0.6
Medication: Paracetamol	0.3	0.5	4.0	-1.0	-0.8	-0.8	0.2	-0.5	-0.3	-0.0	-0.8	-0.1	-0.4	-0.0	-0.2	-2.0	0.6	-0.5
Headache pain in last month	0.3	0.5	1.7	-0.8	-0.5	-0.3	1.3	-0.6	-0.4	-0.4	-1.2	-0.1	-0.4	-1.1	-0.1	0.5	0.8	-0.4
Gout (self-reported)	0.3	0.4	2.2	-0.7	-0.1	-0.5	0.2	-0.8	-0.7	-1.5	-0.7	0.2	-0.0	-0.7	0.2	-0.2	1.1	-0.1
Comparative body size at age 10	0.3	0.8	7.4	-0.9	0.0	-0.0	-0.8	0.8	0.6	0.2	-0.9	-0.6	-0.5	-2.7	-0.6	-0.0	-0.1	-0.6
Wheeze or whistling in the chest in last year	0.3	0.6	2.0	0.2	0.3	-1.1	-0.2	-0.9	-0.8	-0.9	0.2	0.6	0.5	-1.0	0.5	1.1	1.4	0.4
Mouth/teeth dental problems: Loose teeth	0.3	0.4	2.3	-0.3	0.3	-0.5	0.2	-1.0	-0.7	-0.6	-0.3	0.5	0.1	-0.3	0.3	-1.5	0.8	0.1
Angina (self-reported)	0.3	0.4	3.6	-0.2	0.4	-0.7	-0.2	-0.7	-0.5	-0.3	0.1	0.2	-0.1	0.8	0.1	-1.9	0.3	0.0
Medication: Omeprazole	0.3	0.4	1.4	-0.9	-1.2	-0.4	-0.1	-0.6	-0.5	-0.3	-0.8	-0.5	-0.7	-0.3	-0.5	-0.6	0.4	-0.7
Whole body fat mass	0.3	1.2	5.6	-1.6	0.6	-0.4	-1.1	-0.6	-0.3	-0.9	-1.8	-0.2	-0.7	-2.4	-0.3	-0.8	1.0	-0.8
Suffer from ‘nerves’	0.3	0.5	2.0	0.8	0.9	-0.4	-0.1	-0.2	-0.4	-0.4	1.0	0.7	0.7	1.4	0.6	-0.2	0.1	0.8
Whole body fat-free mass	0.3	1.5	13.9	1.1	3.7	0.3	1.3	0.0	-0.2	-0.5	0.2	0.8	0.9	-0.8	0.8	1.5	0.4	0.8
Ever had bowel cancer screening	0.3	0.4	3.2	0.7	-0.0	-0.5	0.5	-0.2	-0.4	-0.4	0.6	0.1	0.1	0.5	0.0	-1.8	-0.5	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	2.0	0.4	0.3	-0.7	0.1	-0.8	-0.5	-0.4	0.5	0.7	0.6	0.2	0.7	-1.4	0.9	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.6	-0.2	0.2	-0.5	0.2	-0.8	-0.8	-0.6	-0.4	0.4	0.1	0.1	0.3	-1.3	1.0	0.1
Asthma (self-reported)	0.3	0.7	2.8	-1.3	-1.1	-0.6	-0.4	-0.0	0.2	0.2	-0.9	-0.7	-0.9	-0.1	-0.7	-1.7	0.6	-0.9
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	0.6	0.5	-1.2	-0.0	-0.7	-1.0	-0.5	0.5	0.4	0.5	0.2	0.5	-0.4	-0.1	0.5
Whole body water mass	0.3	1.7	14.7	1.3	3.8	0.1	1.3	-0.2	-0.3	-0.7	0.3	0.9	1.0	-0.8	0.9	1.4	0.5	0.9
Arm fat mass (left)	0.3	1.3	4.6	-1.7	0.3	-0.7	-0.7	-0.9	-0.6	-1.3	-1.9	-0.1	-0.7	-2.2	-0.3	-1.4	1.2	-0.9
Average weekly beer plus cider intake	0.3	0.4	3.1	-0.6	-0.7	-0.3	0.8	-0.4	-0.5	-0.5	-1.0	0.2	0.0	0.0	0.2	1.8	0.0	-0.0
Fractured/broken bones in last 5 years	0.3	0.4	2.0	-0.3	-0.2	0.3	-0.7	0.6	0.5	0.5	0.2	-0.5	-0.4	1.1	-0.5	-0.6	-1.4	-0.3
Ever depressed for a whole week	0.3	0.4	1.9	0.6	0.5	-0.2	0.7	-0.7	-0.9	-1.4	0.0	0.7	0.5	0.1	0.6	-0.3	0.0	0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.2	-0.8	-1.1	-0.5	-0.2	-0.7	-0.6	-0.6	-0.7	-0.5	-0.7	-0.3	-0.5	-0.6	0.6	-0.7
Alcohol drinker status: Previous	0.3	0.4	1.1	-0.5	-0.7	1.0	-0.7	0.6	0.9	0.5	-0.5	-0.4	-0.3	-1.1	-0.3	-0.1	-0.6	-0.3
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.7	0.0	1.0	-1.6	0.8	-0.9	-0.9	-0.8	0.3	0.9	0.7	0.8	0.7	-0.2	1.0	0.6
Irritable Bowel Disease (IBD)	0.2	0.5	3.0	0.2	0.2	1.0	1.1	0.3	0.3	0.5	-0.0	-0.2	0.1	1.7	0.0	0.6	-1.2	0.1
Ulcerative Colitis (UC)	0.2	0.4	1.4	0.7	0.7	0.7	0.7	0.4	0.3	0.2	0.4	0.2	0.4	1.2	0.3	0.9	-1.0	0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.9	0.6	1.4	-1.0	0.4	-0.7	-0.7	-0.3	0.7	0.8	0.7	0.8	0.7	-0.7	0.9	0.7
Ovarian Cancer	0.2	0.3	0.9	-0.6	-0.8	0.3	0.1	-0.1	0.1	-0.1	-0.4	-0.7	-0.6	-0.9	-0.5	0.1	0.9	-0.6
Bipolar Disorder (2011)	0.2	0.2	1.1	-0.4	-0.4	0.5	0.8	0.4	0.3	0.0	0.0	0.0	-0.1	1.0	-0.1	-0.8	-0.6	-0.3
LDL Cholesterol	0.2	0.3	3.5	-0.1	0.1	-0.8	-1.9	-0.1	-0.1	0.3	0.5	0.1	0.0	-0.3	-0.0	-0.7	0.1	0.1
Blood Platelet Count	0.2	2.4	11.8	-2.1	-1.6	-1.1	-3.4	-0.4	-0.0	-0.5	-1.2	-0.6	-1.0	-2.8	-0.7	1.1	1.5	-1.0
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.8	-0.2	-0.1	0.8	-0.9	0.2	0.5	0.3	-0.4	-0.4	-0.4	-0.7	-0.3	0.8	-0.5	-0.4
Angina	0.2	0.3	3.0	-0.2	0.4	-0.5	-0.3	-0.6	-0.4	-0.3	0.1	0.1	-0.1	0.7	0.1	-1.7	0.2	-0.0
Average weekly fortified wine intake	0.2	0.3	1.2	0.8	0.1	0.6	1.1	0.5	0.5	0.2	0.6	-0.0	-0.0	0.6	-0.2	-0.1	-0.8	0.0
Relative age voice broke	0.2	0.3	1.3	-0.2	0.0	1.1	0.1	0.5	0.6	0.8	0.4	0.0	0.1	-0.2	0.0	0.8	-0.7	0.1
Leg predicted mass (left)	0.2	1.3	10.1	0.3	3.2	0.0	1.4	-0.4	-0.4	-0.9	-0.5	0.7	0.6	-1.5	0.7	1.2	0.9	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.4	0.8	-0.8	0.9	0.2	0.7	0.6	1.0	0.3	-0.1	-0.1	0.2	-0.3	-0.1	-1.2	-0.0
Allergy	0.2	0.4	2.1	0.4	-0.3	1.5	0.1	0.7	0.5	0.3	-0.1	-0.3	-0.3	-0.2	-0.3	1.1	-0.9	-0.3
Fluid intelligence score	0.2	0.4	1.5	-0.1	0.9	-0.5	-1.2	-0.6	-0.5	-0.0	0.5	0.4	0.2	0.3	0.3	-1.2	1.1	0.3
Hip circumference	0.2	0.8	3.2	-1.3	1.0	-0.3	-0.6	-0.4	-0.2	-0.8	-1.8	-0.3	-0.6	-1.4	-0.3	-0.8	0.6	-0.8
Alcohol intake versus 10 years previously	0.2	0.3	1.3	0.2	-0.0	0.9	-1.1	0.3	0.6	1.0	0.3	-0.4	0.0	-0.1	-0.0	0.3	-0.2	0.1
Prospective memory result	0.2	0.3	1.8	0.2	-0.6	-0.2	-0.8	0.4	0.1	-0.0	-0.2	-0.6	-0.4	0.5	-0.4	-1.4	-0.5	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.8	-0.1	-0.1	-0.2	-1.3	-0.4	-0.3	-0.2	0.1	0.4	0.2	1.4	0.3	-0.9	-0.1	0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	2.2	-0.8	0.1	0.0	-0.3	0.1	0.4	0.2	-0.9	-0.4	-0.3	-1.5	-0.2	-0.1	0.0	-0.4
Medication: Amlodipine	0.2	0.3	1.1	-0.4	0.9	-1.0	-0.9	-0.6	-0.4	-0.3	-0.4	-0.3	-0.3	-0.7	-0.2	-0.4	0.6	-0.3
High blood pressure (siblings)	0.2	0.3	1.0	0.4	0.5	-0.1	-0.1	-0.6	-0.5	-0.5	0.1	0.6	0.5	-0.4	0.5	-1.0	0.7	0.4
Arm fat-free mass (right)	0.2	1.2	12.0	1.0	3.5	0.1	1.0	-0.2	-0.4	-0.6	0.1	0.7	0.8	-0.9	0.7	0.9	0.4	0.7
Medication for pain relief, constipation, heartburn	0.2	0.3	3.4	0.1	0.3	0.5	0.5	0.5	0.4	-0.3	0.2	-0.3	-0.2	-0.3	-0.3	1.8	-0.3	-0.1
Medication: Blood pressure	0.2	0.4	2.5	0.0	-0.2	0.8	-1.6	0.2	0.3	0.7	0.1	-0.3	-0.3	0.3	-0.2	-0.6	-1.0	-0.2
Arm predicted mass (right)	0.2	1.1	10.9	1.1	3.3	0.2	1.1	-0.1	-0.3	-0.5	0.2	0.7	0.7	-0.6	0.6	0.9	0.2	0.7
Alcohol intake frequency.	0.2	0.6	1.8	-0.2	-0.5	-0.1	1.2	-0.9	-0.8	-1.2	-0.9	0.1	-0.1	-1.4	0.1	0.1	1.1	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.4	0.1	0.2	0.1	0.4	-0.1	0.1	-0.4	-0.4	0.6	0.3	-0.7	0.3	0.4	1.2	0.2
Leg fat-free mass (right)	0.2	1.3	9.5	0.1	3.1	0.0	1.6	-0.4	-0.4	-1.1	-0.7	0.7	0.5	-1.6	0.6	1.1	1.0	0.4
Leg predicted mass (right)	0.2	1.3	9.4	0.1	3.1	-0.0	1.6	-0.4	-0.4	-1.1	-0.7	0.7	0.5	-1.6	0.6	1.1	1.0	0.4
Basal metabolic rate	0.2	1.1	10.8	0.6	3.3	0.2	1.0	-0.1	-0.2	-0.6	-0.3	0.6	0.6	-1.3	0.6	1.1	0.5	0.5
Arm fat-free mass (left)	0.2	1.0	10.3	0.9	3.2	0.1	0.5	-0.1	-0.3	-0.6	-0.0	0.6	0.6	-1.2	0.6	1.1	0.1	0.5
Diastolic blood pressure, automated reading	0.2	0.7	2.2	-0.8	-0.7	1.5	-0.0	0.9	0.9	0.5	-0.6	-1.0	-1.0	0.6	-1.0	-0.2	-0.4	-0.9
Arm predicted mass (left)	0.2	1.0	9.7	0.9	3.1	0.1	0.4	0.0	-0.2	-0.6	0.0	0.5	0.6	-1.1	0.5	1.2	0.1	0.5
Alzheimer’s Disease (in father)	0.1	0.1	0.5	-0.1	0.5	0.2	0.6	-0.2	-0.1	-0.3	-0.1	0.5	0.1	-0.7	0.1	0.4	0.4	0.0
Blood Eosinophil Count	0.1	1.1	5.0	-2.2	-1.8	-0.0	-0.8	-0.3	-0.1	0.3	-1.4	-0.8	-1.1	-0.2	-0.7	-1.0	-0.9	-1.1
Blood Red Count	0.1	0.6	1.7	1.1	0.2	1.3	0.8	0.8	0.7	0.7	0.9	0.0	0.3	1.1	0.1	-0.4	-0.8	0.4
Blood White Count	0.1	1.0	5.0	-1.3	-1.5	-0.9	-2.2	-1.1	-1.1	-0.6	-0.2	0.2	-0.2	-0.9	0.2	-0.0	1.1	-0.2
Hypothyroidism (self reported)	0.1	0.2	0.7	0.6	0.6	0.1	0.1	0.4	0.6	0.6	0.5	0.2	0.4	-0.2	0.3	0.8	-0.5	0.4
Respiratory disease	0.1	0.3	1.9	-0.7	-0.3	-0.5	0.4	-0.5	-0.3	-0.2	-0.5	-0.2	-0.3	0.2	-0.2	-1.4	1.0	-0.4
Chronotype (morning person)	0.1	0.3	1.5	-0.6	-1.0	0.2	1.2	-0.3	0.2	-0.2	-0.4	-0.5	-0.7	-0.5	-0.5	0.3	0.2	-0.6
Tanning	0.1	0.9	5.9	0.6	1.2	0.8	-2.4	0.6	0.7	0.3	0.6	0.5	0.6	-0.8	0.4	1.4	-0.3	0.6
Hearing difficulty/problems: Yes	0.1	0.2	1.3	-0.0	-0.1	0.0	-0.0	0.1	0.2	0.3	0.2	-0.1	-0.2	1.1	-0.2	-0.2	-1.1	-0.1
Relative age of first facial hair	0.1	0.2	1.3	-0.2	0.2	0.2	1.1	0.0	-0.0	-0.2	0.1	-0.2	-0.1	-0.5	-0.2	-1.0	-0.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.7	0.0	-0.8	0.7	-0.2	0.4	0.3	0.5	-0.2	-0.4	-0.4	0.2	-0.5	0.2	-0.7	-0.4
High blood pressure (mother)	0.1	0.2	1.0	0.1	-0.0	-0.3	-1.0	-0.1	0.0	-0.5	-0.0	0.0	-0.0	-1.0	0.0	0.8	0.0	0.0
Past tobacco smoking	0.1	0.1	0.4	0.2	-0.6	0.3	-0.2	0.3	0.2	-0.2	0.2	-0.4	-0.4	0.5	-0.5	-0.4	0.0	-0.4
Nervous feelings	0.1	0.2	0.6	-0.7	-0.4	-0.2	-0.8	0.1	-0.0	-0.4	-0.3	-0.1	-0.3	-0.3	-0.3	0.8	0.3	-0.3
Had other major operations	0.1	0.1	0.7	-0.4	0.0	-0.4	-0.4	-0.5	-0.4	-0.3	-0.5	0.3	0.0	-0.8	0.2	0.0	-0.3	0.0
Heart attack	0.1	0.2	0.3	-0.3	-0.6	0.0	0.3	0.1	0.1	0.5	-0.5	-0.5	-0.5	0.3	-0.5	0.5	-0.3	-0.5
Medication: Ramipril	0.1	0.1	0.8	0.3	0.2	0.4	0.2	-0.2	-0.1	-0.0	0.1	-0.0	-0.1	0.5	0.1	-0.1	-0.9	0.0
Weight	0.1	0.7	4.0	-0.7	2.0	-0.2	-0.2	-0.3	-0.2	-0.7	-1.3	0.1	-0.1	-1.8	0.1	-0.1	0.6	-0.3
Impedance of arm (right)	0.1	0.5	2.2	0.3	-0.4	0.1	-1.5	0.9	0.8	1.4	0.7	-0.6	-0.1	0.2	-0.3	0.4	-1.0	-0.0
Worrier / anxious feelings	0.1	0.3	0.9	0.1	-0.8	-1.0	-0.7	-0.3	-0.5	0.0	0.0	-0.2	-0.4	0.8	-0.3	-0.9	-0.1	-0.3
Medication: Cholesterol lowering	0.1	0.1	1.1	0.0	-0.9	0.0	-0.0	-0.2	-0.1	0.1	-0.0	-0.1	-0.1	-0.2	-0.0	1.1	0.2	-0.0
Blood clot in the leg (DVT)	0.1	0.1	0.8	0.0	-0.2	0.9	0.2	0.1	0.2	0.4	0.3	-0.2	-0.1	0.1	-0.2	0.7	-0.5	-0.1
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	1.0	-0.4	0.4	-0.2	1.0	0.2	0.0	-0.2	-0.2	-0.0	-0.1	0.1	-0.1	-0.2	0.3	-0.1
Average weekly red wine intake	0.1	0.2	0.9	0.2	-0.2	0.9	-0.2	0.5	0.5	0.8	0.5	0.1	0.3	-0.2	0.2	0.5	-0.1	0.3
Mother’s age at death	0.1	0.1	0.6	0.1	0.3	0.2	0.5	-0.5	-0.5	-0.4	0.4	0.2	0.3	0.2	0.3	-0.0	0.8	0.3
Pain experienced in last month	0.1	0.2	0.7	0.5	0.6	0.4	0.5	0.4	0.4	0.5	0.8	0.2	0.3	0.5	0.2	-0.0	-0.2	0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.6	-0.2	-0.4	0.1	0.6	0.2	0.2	0.6	-0.4	-0.4	-0.4	0.6	-0.4	0.8	-0.4	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.9	0.1	-0.3	1.0	0.6	0.1	0.2	0.4	0.4	-0.3	-0.1	0.4	-0.1	0.7	-0.4	-0.0
Impedance of whole body	0.1	0.6	2.2	0.3	-0.9	0.1	-1.3	0.9	0.8	1.5	0.6	-0.7	-0.2	0.0	-0.4	0.1	-1.1	-0.1
Alcohol usually taken with meals	0.0	0.1	0.2	0.4	0.2	0.2	0.2	0.4	0.2	0.3	0.4	-0.1	0.1	0.3	-0.1	0.1	-0.3	0.1
Impedance of arm (left)	0.0	0.1	0.7	0.3	-0.2	-0.3	-0.7	0.2	0.2	0.8	0.6	-0.2	0.1	0.2	0.1	-0.1	-0.4	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	-0.2	-0.1	-0.0	0.4	0.3	0.2	0.0	0.0	-0.3	-0.3	-0.0	-0.4	-0.4	-0.5	-0.3

Hub : Genes

KLHL7

Models

Trait associations