Hub : Genes

KLHL7

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Visceral Omentum 0.2150 0.0780 7.1e-04 0.064 NA 0.118 NA 0.128 3.0e-04 NA 1.0e-06 NA 3.7e-07
2 GTEx Artery Aorta 0.1790 0.0610 2.4e-04 0.100 NA 0.071 NA 0.073 3.7e-06 NA 9.2e-05 NA 7.3e-05
3 GTEx Cells EBV-transformed lymphocytes 0.2360 0.1050 3.4e-03 0.093 NA 0.026 NA 0.068 5.9e-04 NA 5.0e-02 NA 3.1e-03
4 GTEx Colon Sigmoid 0.1670 0.0740 4.7e-03 0.000 NA -0.004 NA -0.006 3.2e-01 NA 4.7e-01 NA 6.3e-01
5 GTEx Heart Atrial Appendage 0.1240 0.0400 1.8e-05 0.165 NA 0.148 NA 0.164 7.1e-08 NA 3.5e-07 NA 7.6e-08
6 GTEx Heart Left Ventricle 0.0861 0.0332 5.6e-04 0.089 NA 0.079 NA 0.087 1.9e-05 NA 5.4e-05 NA 2.3e-05
7 GTEx Muscle Skeletal 0.0642 0.0243 2.1e-04 0.013 NA 0.008 NA 0.014 1.7e-02 NA 4.6e-02 NA 1.5e-02
8 GTEx Nerve Tibial 0.1657 0.0697 3.2e-03 0.062 NA 0.084 NA 0.094 3.4e-05 NA 1.4e-06 NA 3.8e-07
9 GTEx Pancreas 0.1080 0.0500 6.4e-03 0.059 NA 0.043 NA 0.053 1.6e-03 NA 6.6e-03 NA 2.8e-03
10 GTEx Thyroid 0.1920 0.0570 1.3e-06 0.170 NA 0.112 NA 0.158 5.4e-13 NA 6.4e-09 NA 3.9e-12
11 METSIM Adipose 0.1088 0.0301 3.2e-10 0.027 0.074 0.108 0.106 0.099 5.2e-05 3.2e-11 8.9e-16 1.5e-15 1.5e-14
12 YFS Blood 0.0465 0.0142 7.1e-11 0.052 0.036 0.040 0.042 0.049 1.6e-16 7.5e-12 4.6e-13 1.5e-13 1.1e-15
13 TCGA Lung Squamous Cell Carcinoma 0.0988 0.0501 3.2e-03 -0.002 0.006 0.002 NA -0.001 8.3e-01 6.7e-02 1.9e-01 NA 4.9e-01
14 TCGA Stomach Adenocarcinoma 0.0540 0.0370 3.8e-03 0.005 0.035 0.013 NA 0.011 1.3e-01 1.5e-03 3.4e-02 NA 5.2e-02
15 TCGA Thyroid Carcinoma 0.2470 0.0700 5.4e-14 0.181 0.160 0.174 NA 0.177 2.3e-17 2.4e-15 1.2e-16 NA 6.0e-17

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 0.3 0.4 1.6 -0.6 -0.8 -0.4 1.3 -0.3 -0.2 -1.0 -0.6 -0.2 -0.4 -0.5 -0.3 -0.6 0.6 -0.4
Bipolar Disorder or Schizophrenia 0.9 2.3 7.4 -1.7 -2.7 0.7 0.2 0.8 1.1 0.3 -2.1 -1.7 -1.9 -1.2 -1.8 -1.1 -0.5 -2.0
Depressed Affect (Nagel 2018) 0.9 1.8 6.5 -0.3 0.1 -2.5 -1.7 -2.0 -1.7 -2.1 -0.5 0.6 -0.1 -0.6 0.3 -1.3 1.8 -0.1
Depression (Nagel 2018) 0.6 0.9 5.4 -0.7 -0.7 0.3 -2.3 0.1 0.3 -0.0 -0.8 -0.6 -1.0 -1.8 -0.8 0.4 -0.4 -0.9
Intelligence (Savage-Jansen 2018) 0.2 0.7 2.7 0.0 1.0 -1.6 0.8 -0.9 -0.9 -0.8 0.3 0.9 0.7 0.8 0.7 -0.2 1.0 0.6
Neuroticism (Nagel 2018) 0.6 1.5 4.7 -0.7 -0.2 -2.2 -1.0 -1.9 -1.6 -2.1 -0.6 0.6 -0.0 -0.6 0.3 -1.0 1.8 -0.1
Schizophrenia (2018) 1.4 2.9 7.8 -1.7 -2.8 1.2 -0.6 1.3 1.5 1.1 -2.2 -2.0 -2.1 -1.5 -2.0 -0.8 -1.1 -2.2
Schizophrenia vs Biploar Disorder 1.3 1.7 4.7 -1.4 -2.2 0.5 -1.1 0.8 0.8 0.7 -1.5 -1.5 -1.8 -0.2 -1.6 -1.0 -0.8 -1.7
Worry (Nagel 2018) 0.4 0.9 4.1 0.3 0.3 -2.0 -0.8 -1.3 -1.4 -1.3 0.5 0.8 0.6 0.6 0.7 -0.6 0.8 0.6
Alzheimer’s Disease (in mother) 0.4 0.5 1.3 -1.0 -0.7 -0.0 -1.1 0.3 0.5 0.8 -0.8 -0.5 -0.7 -1.2 -0.6 -0.7 -0.4 -0.7
Alzheimer’s Disease (in father) 0.1 0.1 0.5 -0.1 0.5 0.2 0.6 -0.2 -0.1 -0.3 -0.1 0.5 0.1 -0.7 0.1 0.4 0.4 0.0
Alzheimer’s Disease (including proxy) 0.3 0.5 1.8 -0.3 -0.2 -1.3 0.2 -1.0 -0.7 -0.9 -0.4 0.6 0.1 -1.3 0.3 -0.2 0.8 0.1
Crohns Disease (2017) 0.3 0.6 2.5 -0.7 -0.7 0.9 0.8 0.1 0.3 0.7 -0.7 -0.7 -0.7 1.6 -0.6 -0.2 -0.8 -0.7
Irritable Bowel Disease (IBD) 0.2 0.5 3.0 0.2 0.2 1.0 1.1 0.3 0.3 0.5 -0.0 -0.2 0.1 1.7 0.0 0.6 -1.2 0.1
Ulcerative Colitis (UC) 0.2 0.4 1.4 0.7 0.7 0.7 0.7 0.4 0.3 0.2 0.4 0.2 0.4 1.2 0.3 0.9 -1.0 0.5
Major Depression (MDD) 0.3 0.4 0.7 0.8 0.3 -0.9 0.7 -0.8 -0.7 -0.4 0.7 0.7 0.6 0.1 0.6 -0.7 0.1 0.6
Reaction Time 2.2 4.1 12.2 0.7 2.4 -2.8 -0.3 -2.5 -2.5 -3.5 0.9 2.2 1.9 -0.6 2.2 -0.9 2.0 1.9
Verbal and Numeric Reasoning (VNR) 0.2 0.6 1.9 0.6 1.4 -1.0 0.4 -0.7 -0.7 -0.3 0.7 0.8 0.7 0.8 0.7 -0.7 0.9 0.7
Breast Cancer 0.6 1.5 3.3 -1.7 -0.9 0.8 -0.6 1.1 1.2 1.4 -1.8 -1.5 -1.4 -1.4 -1.3 -0.2 -0.8 -1.5
Ovarian Cancer 0.2 0.3 0.9 -0.6 -0.8 0.3 0.1 -0.1 0.1 -0.1 -0.4 -0.7 -0.6 -0.9 -0.5 0.1 0.9 -0.6
Prostate Cancer 0.4 0.5 3.0 0.5 0.4 -0.3 0.1 -0.4 -0.3 -0.6 0.3 0.7 0.6 -0.8 0.6 1.7 1.0 0.6
Age at First Birth 1.0 1.4 3.3 -1.5 -1.4 1.2 0.1 1.4 1.2 1.2 -1.1 -1.3 -1.1 -0.5 -1.2 0.5 -1.8 -1.1
Bipolar Disorder (2011) 0.2 0.2 1.1 -0.4 -0.4 0.5 0.8 0.4 0.3 0.0 0.0 0.0 -0.1 1.0 -0.1 -0.8 -0.6 -0.3
Body Mass Index (BMI) (2010) 0.3 0.5 1.3 -0.6 -0.2 -1.1 0.7 -0.9 -0.8 -1.1 -0.7 0.0 -0.2 -1.1 -0.0 0.0 0.9 -0.3
Coronary Artery Disease (CAD) 0.3 0.4 2.1 -0.5 0.1 -1.0 -1.5 -0.6 -0.6 -0.3 0.2 -0.3 -0.3 0.3 -0.2 0.7 0.5 -0.2
Crohns Disease (2012) 2.3 3.7 6.9 -2.3 -2.0 2.6 -0.8 1.8 2.0 1.9 -2.4 -2.2 -2.2 0.0 -2.1 1.3 -1.3 -2.2
Mean Putamen Volume 0.3 0.3 1.1 -0.5 -0.8 -0.3 1.0 -0.2 -0.2 -0.6 -0.7 -0.2 -0.5 0.3 -0.4 -0.9 -0.0 -0.5
Fasting Glucose 0.3 0.4 3.0 -0.1 -0.1 0.9 1.7 0.4 0.4 0.4 -0.6 -0.1 -0.1 0.5 -0.1 0.7 -0.9 -0.1
HbA1C 0.6 0.7 2.0 -0.7 -0.2 0.6 -0.3 0.9 1.0 0.9 -0.6 -0.9 -1.1 -0.9 -1.0 0.1 -1.4 -1.0
HDL Cholesterol 0.3 0.6 2.4 -0.4 -0.7 0.4 1.3 -0.3 -0.5 -0.7 -0.3 -0.3 -0.3 -1.5 -0.3 1.5 0.6 -0.3
LDL Cholesterol 0.2 0.3 3.5 -0.1 0.1 -0.8 -1.9 -0.1 -0.1 0.3 0.5 0.1 0.0 -0.3 -0.0 -0.7 0.1 0.1
Lupus 0.8 1.2 2.9 -1.3 -0.6 1.5 -0.6 1.1 1.3 1.4 -1.2 -1.1 -1.0 -0.6 -1.1 1.7 -0.1 -1.1
Neuroticism (2016) 0.4 0.6 2.1 -1.0 -1.5 0.0 -0.2 0.5 0.7 0.1 -1.0 -0.6 -1.1 -0.0 -0.9 -0.9 -0.3 -1.0
Primary Biliary Cirrhosis 0.8 1.1 2.0 1.4 1.1 -1.1 -0.7 -0.8 -0.8 -0.6 1.2 1.1 1.2 0.1 1.1 -1.4 1.2 1.2
Rheumatoid Arthritis 2.3 3.2 6.0 2.1 2.4 -1.8 -0.3 -1.6 -1.6 -1.2 2.4 2.2 2.1 1.3 2.0 -0.4 1.3 2.2
Schizophrenia (2014) 2.0 4.5 12.3 -2.3 -3.5 1.2 -0.5 1.2 1.6 1.1 -2.9 -2.5 -2.8 -1.0 -2.5 -2.0 -1.1 -2.8
Triglycerides 5.0 8.2 12.0 -2.7 -3.0 2.9 -1.3 3.5 3.5 3.4 -2.8 -3.2 -3.1 -0.6 -3.2 -1.3 -3.4 -3.1
Type 2 Diabetes (T2D) (2012) 0.4 0.4 4.6 -0.3 -0.2 -0.5 -2.1 0.5 0.4 0.3 0.1 -0.1 0.1 -0.5 -0.0 -0.6 0.0 0.1
Ulcerative Colitis 0.3 0.5 1.5 0.8 0.8 0.8 -0.7 0.5 0.4 0.3 0.6 0.5 0.7 0.8 0.5 1.2 -0.6 0.7
Blood Eosinophil Count 0.1 1.1 5.0 -2.2 -1.8 -0.0 -0.8 -0.3 -0.1 0.3 -1.4 -0.8 -1.1 -0.2 -0.7 -1.0 -0.9 -1.1
Blood Platelet Count 0.2 2.4 11.8 -2.1 -1.6 -1.1 -3.4 -0.4 -0.0 -0.5 -1.2 -0.6 -1.0 -2.8 -0.7 1.1 1.5 -1.0
Blood Red Count 0.1 0.6 1.7 1.1 0.2 1.3 0.8 0.8 0.7 0.7 0.9 0.0 0.3 1.1 0.1 -0.4 -0.8 0.4
Blood White Count 0.1 1.0 5.0 -1.3 -1.5 -0.9 -2.2 -1.1 -1.1 -0.6 -0.2 0.2 -0.2 -0.9 0.2 -0.0 1.1 -0.2
Heel T-Score 0.6 4.7 9.4 -0.4 -3.0 2.6 -1.0 2.8 2.5 3.1 -0.8 -2.5 -2.2 0.3 -2.5 -0.4 -2.9 -2.0
BMI 0.3 2.0 5.1 -2.0 -0.5 -1.2 0.5 -1.6 -1.3 -2.2 -2.2 0.2 -0.6 -1.9 -0.1 -1.0 2.0 -0.8
Height 0.7 12.8 92.2 5.5 9.6 0.8 -0.8 1.0 0.5 1.4 4.4 2.3 3.5 2.2 2.7 1.3 -1.4 3.7
Waist Hip Ratio (WHR) 1.0 4.6 8.2 -2.0 -1.8 2.5 -1.8 2.2 2.2 2.5 -1.6 -2.1 -2.0 -2.3 -2.1 2.9 -1.9 -2.0
Systolic Blood Pressure 1.4 6.8 11.4 -2.8 -2.9 2.8 -1.0 2.7 2.8 3.0 -2.3 -3.4 -3.2 0.6 -3.1 0.2 -2.7 -3.0
Smoking Status 0.9 2.2 5.0 0.3 1.7 -1.6 0.1 -1.8 -1.7 -2.0 0.3 1.7 1.4 -1.3 1.6 0.8 2.2 1.3
Allergy or Eczema 1.6 4.2 12.1 0.8 1.4 -3.5 1.4 -2.5 -2.3 -2.6 1.2 2.3 2.1 0.4 2.2 -1.3 2.6 2.0
Cardiovascular Disease 1.3 4.4 12.0 -2.8 -2.5 0.9 -0.5 1.1 1.5 1.1 -3.5 -2.5 -2.9 -1.5 -2.5 -0.9 -1.2 -2.9
Hypothyroidism (self reported) 0.1 0.2 0.7 0.6 0.6 0.1 0.1 0.4 0.6 0.6 0.5 0.2 0.4 -0.2 0.3 0.8 -0.5 0.4
Respiratory disease 0.1 0.3 1.9 -0.7 -0.3 -0.5 0.4 -0.5 -0.3 -0.2 -0.5 -0.2 -0.3 0.2 -0.2 -1.4 1.0 -0.4
Type 2 Diabetes (T2D) (2018) 2.5 4.6 11.9 -3.5 -3.1 0.6 -1.1 1.3 1.5 1.2 -3.1 -2.4 -2.5 -2.4 -2.2 0.7 -0.7 -2.6
Lung FEV1/FVC ratio 0.3 1.7 3.5 1.4 1.0 -1.4 -0.4 -1.1 -1.1 -1.1 1.8 1.9 1.7 1.0 1.6 -0.3 0.8 1.7
Lung FVC 1.6 7.9 13.8 3.6 2.7 -1.6 3.7 -1.4 -1.5 -1.6 3.2 3.3 3.6 2.4 3.2 -3.3 1.3 3.5
Neuroticism 0.4 1.0 3.8 -0.8 -0.0 -1.7 -1.9 -1.2 -1.1 -1.4 -0.5 0.6 0.0 -0.9 0.3 0.2 1.4 -0.0
Chronotype (morning person) 0.1 0.3 1.5 -0.6 -1.0 0.2 1.2 -0.3 0.2 -0.2 -0.4 -0.5 -0.7 -0.5 -0.5 0.3 0.2 -0.6
Hair Pigment 0.3 8.0 12.7 2.6 1.7 -3.2 1.7 -3.3 -3.3 -3.1 2.7 2.8 2.5 3.6 2.6 -3.1 2.9 2.6
Tanning 0.1 0.9 5.9 0.6 1.2 0.8 -2.4 0.6 0.7 0.3 0.6 0.5 0.6 -0.8 0.4 1.4 -0.3 0.6
Hand grip strength (left) 0.7 2.0 6.7 1.2 0.8 2.6 0.1 2.4 2.1 2.0 0.8 -0.5 0.2 -0.3 -0.3 1.7 -1.6 0.2
Number of treatments/medications taken 0.4 0.8 2.2 -1.2 -0.9 -0.5 -1.1 -0.1 0.1 0.1 -1.2 -0.7 -1.0 -1.2 -0.7 -1.5 -0.2 -1.0
Average weekly spirits intake 0.9 1.1 2.6 0.9 0.9 -1.1 1.6 -1.5 -1.2 -0.9 0.4 1.0 0.9 -0.1 1.1 -0.7 1.4 0.9
Sensitivity / hurt feelings 0.6 1.0 3.2 -0.2 0.2 -1.4 -0.7 -1.6 -1.3 -1.8 0.0 1.0 0.5 -0.4 0.8 0.1 1.7 0.5
Frequency of depressed mood in last 2 weeks 1.5 2.1 9.4 -1.6 -1.3 0.7 -3.1 0.8 1.0 0.7 -1.3 -1.2 -1.6 -2.0 -1.5 0.1 -0.6 -1.6
Hearing difficulty/problems: Yes 0.1 0.2 1.3 -0.0 -0.1 0.0 -0.0 0.1 0.2 0.3 0.2 -0.1 -0.2 1.1 -0.2 -0.2 -1.1 -0.1
Relative age of first facial hair 0.1 0.2 1.3 -0.2 0.2 0.2 1.1 0.0 -0.0 -0.2 0.1 -0.2 -0.1 -0.5 -0.2 -1.0 -0.0 -0.1
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 0.8 -0.2 -0.1 0.8 -0.9 0.2 0.5 0.3 -0.4 -0.4 -0.4 -0.7 -0.3 0.8 -0.5 -0.4
Ever used hormone-replacement therapy (HRT) 0.3 0.4 3.9 -0.6 0.3 -0.1 -0.5 -0.5 -0.4 -0.1 -0.6 0.2 0.2 0.6 0.3 -2.0 0.5 0.1
Ever had hysterectomy (womb removed) 1.0 1.1 2.6 -0.4 -1.0 1.6 -0.4 1.2 1.5 1.6 -0.2 -1.1 -0.9 -0.4 -1.0 0.5 -1.6 -0.8
Systolic blood pressure, automated reading 1.3 3.9 6.8 -2.1 -2.1 1.8 -1.9 2.0 2.0 2.0 -1.4 -2.6 -2.5 0.4 -2.5 -0.6 -1.7 -2.4
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 5.8 -1.5 -0.7 0.3 -2.4 0.7 0.6 0.6 -1.2 -0.9 -0.9 -0.9 -0.9 1.1 -0.6 -1.0
Angina 0.2 0.3 3.0 -0.2 0.4 -0.5 -0.3 -0.6 -0.4 -0.3 0.1 0.1 -0.1 0.7 0.1 -1.7 0.2 -0.0
Medication for hormone replacement therapy 0.7 0.8 4.7 0.5 0.5 -0.5 0.6 -0.7 -0.8 -0.7 0.2 0.5 0.6 1.5 0.7 -2.2 0.3 0.6
Vitamin and mineral supplements 2.7 3.7 9.4 -0.9 -2.1 3.1 -0.9 2.6 2.7 2.6 -0.7 -2.1 -1.7 1.1 -1.9 1.0 -1.5 -1.6
Supplements: Zinc 0.9 1.0 2.1 0.4 1.4 -1.4 -0.3 -0.9 -0.9 -1.1 0.2 1.0 0.9 -1.4 1.0 0.9 1.0 0.9
Medication: Co-codamol 3.3 3.9 9.9 1.2 1.8 -1.7 1.4 -2.5 -2.5 -2.6 1.0 2.2 2.0 0.4 2.1 -1.3 3.1 1.9
Medication: Metformin 1.8 2.6 6.2 -2.5 -1.9 0.3 -2.1 1.0 1.1 1.0 -2.1 -1.6 -1.8 -1.5 -1.7 1.6 -0.6 -1.9
Diabetes (father) 2.2 2.7 6.3 -2.5 -1.7 1.6 -1.4 1.5 1.7 1.6 -1.7 -1.6 -1.7 -1.4 -1.6 -1.3 -1.4 -1.7
Diabetes (mother) 1.2 1.6 5.7 -1.4 -2.4 1.1 -0.7 1.0 1.3 0.5 -1.4 -1.3 -1.5 -0.9 -1.4 -0.3 0.2 -1.5
Severe depression (siblings) 3.3 3.7 6.6 2.0 1.6 -2.0 1.6 -2.5 -2.6 -2.5 1.5 2.1 2.0 0.3 2.1 0.1 2.0 2.0
Pack years adult smoking proportion 0.4 0.7 1.8 -1.0 -1.4 0.5 -0.7 0.4 0.5 -0.0 -1.1 -0.7 -0.9 -1.3 -0.7 0.2 -0.6 -0.9
Impedance of leg (right) 0.3 1.6 4.8 0.8 -1.1 0.9 -2.0 1.6 1.4 2.2 1.1 -1.0 -0.3 0.7 -0.7 0.5 -2.0 -0.2
Leg fat-free mass (left) 0.3 1.4 10.4 0.4 3.2 0.0 1.4 -0.4 -0.5 -0.9 -0.4 0.8 0.7 -1.5 0.8 1.2 0.9 0.6
Trunk fat percentage 0.4 1.7 5.7 -1.9 0.1 -1.1 -1.4 -1.1 -0.8 -1.2 -1.9 -0.1 -0.6 -2.4 -0.2 -1.7 1.4 -0.8
Hand grip strength (right) 0.8 2.2 7.6 1.3 0.4 2.7 0.5 2.6 2.2 1.8 0.7 -0.8 -0.1 0.7 -0.7 0.7 -2.3 -0.1
Townsend deprivation index at recruitment 0.6 0.8 1.9 -1.3 -1.1 -0.2 0.8 -0.7 -0.4 -0.8 -1.3 -0.3 -0.7 -1.2 -0.4 1.4 0.9 -0.7
Current tobacco smoking 2.4 4.0 10.0 1.1 1.8 -1.7 1.0 -2.5 -2.3 -3.0 1.1 2.4 2.0 -1.2 2.3 0.1 3.2 1.9
Average weekly fortified wine intake 0.2 0.3 1.2 0.8 0.1 0.6 1.1 0.5 0.5 0.2 0.6 -0.0 -0.0 0.6 -0.2 -0.1 -0.8 0.0
Maternal smoking around birth 0.8 1.2 3.1 -1.0 -1.1 1.1 -1.8 1.0 0.9 0.5 -0.9 -1.2 -1.3 -1.3 -1.2 -0.9 -0.4 -1.2
Fed-up feelings 1.2 2.2 4.3 -1.9 -2.0 0.6 -1.7 0.9 1.2 0.4 -2.0 -1.6 -2.1 0.2 -1.8 -0.9 -0.2 -2.1
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 6.3 -1.1 -1.0 1.3 -2.5 0.8 1.0 0.7 -1.1 -0.9 -1.2 -1.1 -1.1 0.2 -0.6 -1.2
Relative age voice broke 0.2 0.3 1.3 -0.2 0.0 1.1 0.1 0.5 0.6 0.8 0.4 0.0 0.1 -0.2 0.0 0.8 -0.7 0.1
Taking other prescription medications 1.4 2.2 5.2 -2.1 -1.4 0.4 -2.3 0.6 0.9 0.8 -1.6 -1.8 -1.9 -1.5 -1.7 -1.2 -0.7 -1.9
Age when periods started (menarche) 2.1 4.9 8.0 2.5 1.8 -2.3 2.0 -2.0 -2.2 -1.8 2.4 2.7 2.8 0.5 2.8 -0.4 2.5 2.8
Bilateral oophorectomy (both ovaries removed) 1.4 1.6 4.1 -0.7 -0.9 2.0 -1.4 1.4 1.4 1.6 -0.8 -1.4 -1.3 -0.7 -1.3 0.7 -1.4 -1.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.7 0.0 -0.8 0.7 -0.2 0.4 0.3 0.5 -0.2 -0.4 -0.4 0.2 -0.5 0.2 -0.7 -0.4
Tinnitus: Yes, but not now, but have in the past 2.4 2.5 4.2 1.4 1.3 -1.8 0.2 -1.9 -2.0 -1.5 1.5 1.8 1.7 1.1 1.7 -2.0 1.4 1.7
Qualifications: CSEs or equivalent 0.8 1.1 4.7 -1.4 -1.3 -0.7 2.2 -0.5 -0.5 -0.9 -1.9 -0.1 -0.5 -1.2 -0.3 -0.4 0.8 -0.7
Serious illness, injury or assault to yourself 2.1 2.6 5.7 -2.3 -2.3 0.1 -0.5 0.6 0.8 0.5 -2.4 -2.0 -2.3 -0.8 -2.0 -1.0 -0.5 -2.3
High blood pressure 1.1 2.9 5.6 -2.1 -1.7 1.2 -0.9 1.3 1.5 1.4 -2.2 -2.2 -2.4 -0.1 -2.2 -1.1 -1.4 -2.3
Hayfever, allergic rhinitis or eczema 0.6 1.3 4.9 0.3 0.8 -2.2 0.9 -1.2 -1.1 -1.1 0.6 1.1 1.1 0.3 1.1 -1.0 1.4 1.0
Multivitamins +/- minerals 0.5 0.6 1.7 0.2 1.2 -1.3 0.7 -0.9 -1.0 -0.7 -0.1 0.7 0.5 -0.9 0.6 0.5 -0.3 0.5
Stomach or abdominal pain in last month 1.4 1.8 7.8 -1.7 -1.0 -1.7 -0.4 -1.2 -1.2 -2.0 -1.5 -0.4 -0.7 -2.8 -0.4 0.1 1.1 -0.8
Supplements: Glucosamine 0.5 0.6 2.0 0.9 1.4 -0.7 -0.2 -0.5 -0.8 -0.2 0.9 0.8 0.9 -0.5 0.8 0.9 0.5 0.9
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 2.9 -0.1 -0.6 -0.8 0.8 -0.8 -0.6 -1.7 -0.2 0.1 -0.1 -0.3 0.1 -1.6 0.1 -0.1
Medication: Atenolol 0.9 1.1 4.8 -1.6 -0.9 0.3 -2.2 0.7 0.8 1.2 -0.8 -1.0 -1.1 0.0 -1.0 0.5 -0.4 -1.1
Medication: Levothyroxine sodium 0.7 1.3 3.3 -1.5 -0.9 -0.1 -1.8 0.4 0.8 0.6 -1.5 -1.1 -1.1 -1.6 -0.9 -1.3 -0.7 -1.2
Sitting height 0.6 4.4 26.4 2.9 5.1 0.9 0.8 1.0 0.6 0.9 2.4 1.1 2.0 1.1 1.4 3.0 -1.0 2.0
Chronic bronchitis/emphysema (father) 1.7 2.0 3.3 -1.1 -1.8 1.6 0.5 1.5 1.6 1.3 -1.0 -1.6 -1.5 -0.2 -1.7 -1.7 -1.4 -1.5
High blood pressure (mother) 0.1 0.2 1.0 0.1 -0.0 -0.3 -1.0 -0.1 0.0 -0.5 -0.0 0.0 -0.0 -1.0 0.0 0.8 0.0 0.0
Body mass index (BMI) 0.5 2.0 6.8 -2.5 -1.0 -0.5 -1.0 -0.8 -0.5 -1.3 -2.6 -0.5 -1.3 -2.0 -0.7 -1.6 1.2 -1.4
Impedance of leg (left) 0.3 1.7 5.0 0.1 -1.6 1.0 -1.9 1.8 1.6 2.2 0.4 -1.3 -0.8 0.2 -1.1 0.2 -1.9 -0.7
Leg predicted mass (left) 0.2 1.3 10.1 0.3 3.2 0.0 1.4 -0.4 -0.4 -0.9 -0.5 0.7 0.6 -1.5 0.7 1.2 0.9 0.5
Trunk fat mass 0.3 1.2 5.2 -1.4 1.1 -0.8 -1.0 -0.8 -0.6 -1.1 -1.6 0.0 -0.3 -2.3 0.0 -1.1 1.2 -0.5
Waist circumference 0.8 3.1 9.5 -2.9 -0.7 0.8 -1.6 0.7 0.9 0.4 -3.1 -1.6 -2.0 -2.9 -1.7 0.1 -0.1 -2.2
Number of incorrect matches in round 2.4 3.9 6.6 -1.4 -2.4 2.4 -1.4 2.2 2.1 2.4 -1.4 -2.4 -2.2 -0.2 -2.3 0.1 -2.6 -2.1
Past tobacco smoking 0.1 0.1 0.4 0.2 -0.6 0.3 -0.2 0.3 0.2 -0.2 0.2 -0.4 -0.4 0.5 -0.5 -0.4 0.0 -0.4
Alcohol usually taken with meals 0.0 0.1 0.2 0.4 0.2 0.2 0.2 0.4 0.2 0.3 0.4 -0.1 0.1 0.3 -0.1 0.1 -0.3 0.1
Nervous feelings 0.1 0.2 0.6 -0.7 -0.4 -0.2 -0.8 0.1 -0.0 -0.4 -0.3 -0.1 -0.3 -0.3 -0.3 0.8 0.3 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.4 -0.7 -1.3 0.8 -1.5 0.5 0.6 0.5 -0.8 -0.9 -1.2 -0.8 -1.1 -0.2 -0.5 -1.1
Hearing difficulty/problems with background noise 0.3 0.4 1.6 -0.4 -0.6 -1.3 -0.1 -0.8 -0.7 -0.8 -0.6 -0.1 -0.5 -0.3 -0.3 -1.0 0.5 -0.5
Hair/balding pattern: Pattern 2 0.5 0.7 3.9 0.7 -0.0 -0.0 -0.1 -0.7 -0.6 -0.9 0.8 0.9 0.7 0.4 0.7 2.0 1.1 0.7
Had menopause 0.6 0.7 4.5 0.4 0.6 -0.8 -1.4 -0.6 -0.5 -0.3 0.6 0.2 0.3 1.2 0.3 -2.1 0.0 0.3
Had other major operations 0.1 0.1 0.7 -0.4 0.0 -0.4 -0.4 -0.5 -0.4 -0.3 -0.5 0.3 0.0 -0.8 0.2 0.0 -0.3 0.0
Forced vital capacity (FVC) 2.8 11.0 27.7 4.0 5.3 -2.3 4.0 -1.9 -2.3 -2.4 3.3 4.0 4.3 0.9 4.0 -1.3 1.9 4.2
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 1.4 0.8 -0.8 0.9 0.2 0.7 0.6 1.0 0.3 -0.1 -0.1 0.2 -0.3 -0.1 -1.2 -0.0
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 2.1 -1.5 -1.1 -0.1 0.3 -0.7 -0.6 -1.1 -1.4 -0.4 -0.8 -0.6 -0.5 -1.3 0.1 -0.9
Qualifications: None of the above 0.4 0.9 7.6 0.3 0.8 -0.3 -2.8 -0.5 -0.5 0.0 0.9 0.4 0.5 0.8 0.4 -1.1 0.6 0.5
Financial difficulties in last 2 years 0.5 0.7 1.4 -1.0 -1.2 1.0 -0.5 0.9 1.1 0.4 -0.7 -0.8 -0.9 -0.6 -0.9 0.5 -0.9 -0.9
Mouth/teeth dental problems 0.4 0.6 1.7 0.2 -0.8 1.0 1.3 1.0 0.8 0.2 -0.1 -0.6 -0.5 -0.1 -0.7 0.8 -1.2 -0.5
Heart attack 0.1 0.2 0.3 -0.3 -0.6 0.0 0.3 0.1 0.1 0.5 -0.5 -0.5 -0.5 0.3 -0.5 0.5 -0.3 -0.5
Allergy 0.2 0.4 2.1 0.4 -0.3 1.5 0.1 0.7 0.5 0.3 -0.1 -0.3 -0.3 -0.2 -0.3 1.1 -0.9 -0.3
Pain all over the body in last month 0.6 0.6 1.7 1.0 1.3 0.7 0.1 0.2 0.3 0.5 0.8 0.7 0.9 1.3 0.8 -0.1 -0.5 1.0
Diabetes (self-reported) 1.5 2.4 5.3 -1.5 -2.3 0.6 -1.9 1.5 1.4 1.5 -1.2 -1.6 -1.6 -0.7 -1.6 1.9 -1.4 -1.6
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 3.4 0.9 0.9 -0.6 1.9 -0.3 -0.5 -0.9 1.1 1.1 1.1 0.8 1.0 0.6 0.3 1.2
Medication: Ramipril 0.1 0.1 0.8 0.3 0.2 0.4 0.2 -0.2 -0.1 -0.0 0.1 -0.0 -0.1 0.5 0.1 -0.1 -0.9 0.0
Medication: Simvastatin 0.9 1.3 3.6 -1.4 -1.9 0.7 -0.4 0.7 0.8 0.9 -1.7 -1.1 -1.4 -1.0 -1.2 1.0 -0.4 -1.4
Fluid intelligence score 0.2 0.4 1.5 -0.1 0.9 -0.5 -1.2 -0.6 -0.5 -0.0 0.5 0.4 0.2 0.3 0.3 -1.2 1.1 0.3
Illnesses of siblings 0.3 0.4 1.9 0.8 0.0 0.1 0.9 0.3 0.0 0.3 1.0 -0.2 0.3 1.4 0.0 1.0 -0.7 0.4
Neuroticism score 0.3 0.7 2.3 -0.6 -0.1 -1.5 -0.9 -1.1 -1.1 -1.5 -0.6 0.5 -0.1 -0.3 0.2 -0.8 1.2 -0.1
Weight 0.1 0.7 4.0 -0.7 2.0 -0.2 -0.2 -0.3 -0.2 -0.7 -1.3 0.1 -0.1 -1.8 0.1 -0.1 0.6 -0.3
Impedance of arm (right) 0.1 0.5 2.2 0.3 -0.4 0.1 -1.5 0.9 0.8 1.4 0.7 -0.6 -0.1 0.2 -0.3 0.4 -1.0 -0.0
Arm fat percentage (right) 0.5 1.8 5.2 -2.0 -0.8 -0.8 -2.0 -0.9 -0.5 -1.1 -1.9 -0.4 -1.0 -2.3 -0.5 -1.6 1.1 -1.1
Trunk fat-free mass 0.3 1.8 15.1 1.8 3.9 0.7 1.1 0.4 0.2 0.0 0.7 0.7 1.0 -0.2 0.8 1.8 -0.2 1.0
Hip circumference 0.2 0.8 3.2 -1.3 1.0 -0.3 -0.6 -0.4 -0.2 -0.8 -1.8 -0.3 -0.6 -1.4 -0.3 -0.8 0.6 -0.8
Time employed in main current job 0.3 0.4 1.9 -0.1 0.9 -0.5 -0.3 -0.4 -0.4 -0.5 0.6 0.5 0.5 -0.2 0.4 -1.4 1.1 0.4
Alcohol intake versus 10 years previously 0.2 0.3 1.3 0.2 -0.0 0.9 -1.1 0.3 0.6 1.0 0.3 -0.4 0.0 -0.1 -0.0 0.3 -0.2 0.1
Father’s age at death 0.9 1.2 2.9 -0.7 -0.9 1.1 -0.1 1.3 1.3 1.6 -1.0 -1.1 -0.9 -1.2 -1.0 0.3 -1.7 -1.0
Worrier / anxious feelings 0.1 0.3 0.9 0.1 -0.8 -1.0 -0.7 -0.3 -0.5 0.0 0.0 -0.2 -0.4 0.8 -0.3 -0.9 -0.1 -0.3
Frequency of tiredness / lethargy in last 2 weeks 3.3 5.4 11.0 -3.3 -2.5 1.4 -2.9 1.6 1.9 1.7 -3.2 -2.2 -2.6 -2.6 -2.3 1.3 -0.6 -2.7
Falls in the last year 0.4 0.6 2.6 -0.7 -0.7 -0.1 -1.6 0.4 0.3 0.5 -0.4 -0.5 -0.6 0.5 -0.5 -1.6 -0.7 -0.5
Hair/balding pattern: Pattern 3 0.5 0.7 1.4 -1.0 -1.2 0.8 0.6 0.7 0.9 0.8 -1.0 -0.9 -0.8 0.7 -0.8 -0.4 -1.0 -0.8
Number of live births 1.3 1.9 8.0 -0.3 1.3 -2.2 0.9 -1.8 -1.8 -1.6 -0.3 1.1 0.8 -0.2 1.0 0.2 2.8 0.6
Forced expiratory volume in 1-second (FEV1) 2.3 7.6 16.8 3.4 4.1 -1.9 3.3 -1.5 -1.8 -2.0 2.8 3.4 3.7 1.0 3.4 -1.4 1.6 3.5
Pulse rate 0.7 1.2 4.5 -2.1 -1.2 0.1 0.2 0.2 0.5 -0.2 -2.0 -0.9 -1.4 -1.2 -1.1 -0.6 0.1 -1.4
Happiness 0.5 0.6 1.9 -0.8 -0.7 -0.3 -0.7 -0.1 -0.2 -0.8 -1.1 -0.5 -1.0 0.4 -0.8 -1.4 -0.2 -1.0
Noisy workplace 0.9 1.1 2.5 0.7 0.0 -1.4 0.2 -1.4 -1.3 -1.6 0.8 1.1 0.8 0.4 1.0 -1.3 1.2 0.9
Qualifications: A levels/AS levels or equivalent 0.4 1.0 2.8 -0.2 1.2 -1.7 0.5 -1.2 -1.1 -1.4 -0.5 0.8 0.6 -1.0 0.9 -1.0 0.9 0.5
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.5 -0.7 -1.1 0.5 -0.3 0.9 1.0 0.8 -0.5 -0.7 -0.7 -1.0 -0.8 0.8 -1.2 -0.7
Mouth/teeth dental problems: Dentures 0.3 0.5 3.6 -0.7 0.1 -0.6 -1.9 -0.2 -0.1 -0.1 -0.7 -0.5 -0.5 -1.0 -0.3 0.6 0.8 -0.5
Asthma 0.4 0.8 2.9 -1.4 -1.1 -0.4 -0.6 0.2 0.4 0.5 -0.9 -0.8 -1.0 -0.1 -0.9 -1.7 0.3 -1.0
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 2.7 -1.0 -1.1 0.1 0.4 0.2 0.2 -0.1 -1.6 -0.4 -0.7 -0.8 -0.5 -1.2 0.4 -0.8
Medication: Cholesterol lowering 0.1 0.1 1.1 0.0 -0.9 0.0 -0.0 -0.2 -0.1 0.1 -0.0 -0.1 -0.1 -0.2 -0.0 1.1 0.2 -0.0
Depression (self-reported) 0.3 0.4 2.0 -1.1 -1.0 -0.5 -1.4 -0.3 -0.4 -0.4 -0.4 -0.2 -0.5 -0.3 -0.3 -0.5 -0.4 -0.5
Medication: Lansoprazole 2.9 3.2 6.0 -2.3 -2.5 0.7 -1.4 1.2 1.3 1.4 -2.0 -2.3 -2.2 -0.7 -2.1 1.4 -2.0 -2.2
Prospective memory result 0.2 0.3 1.8 0.2 -0.6 -0.2 -0.8 0.4 0.1 -0.0 -0.2 -0.6 -0.4 0.5 -0.4 -1.4 -0.5 -0.3
Lung cancer (father) 0.8 0.9 2.1 1.4 0.8 -0.5 1.1 -0.9 -1.0 -0.8 1.3 1.1 1.1 0.7 1.1 0.4 0.7 1.1
Illnesses of mother 0.5 0.6 2.7 -0.6 -0.3 1.6 -0.0 1.2 0.9 1.2 -0.4 -0.5 -0.4 0.7 -0.5 -0.3 -0.9 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 1.1 3.4 9.6 2.5 3.1 -0.9 2.2 -0.5 -0.8 -0.5 1.9 2.3 2.6 0.8 2.3 -0.9 0.5 2.5
Pulse wave Arterial Stiffness index 1.9 2.2 4.7 1.8 2.1 -1.1 -0.3 -1.2 -1.1 -0.9 1.8 1.7 1.7 1.0 1.7 -2.2 0.5 1.8
Impedance of arm (left) 0.0 0.1 0.7 0.3 -0.2 -0.3 -0.7 0.2 0.2 0.8 0.6 -0.2 0.1 0.2 0.1 -0.1 -0.4 0.2
Arm fat mass (right) 0.3 1.2 4.2 -1.6 0.3 -0.7 -1.1 -0.7 -0.5 -1.2 -1.8 -0.2 -0.7 -2.0 -0.3 -1.4 1.1 -0.8
Trunk predicted mass 0.3 1.8 14.9 1.9 3.9 0.6 1.1 0.4 0.1 -0.0 0.8 0.7 1.1 -0.2 0.8 1.9 -0.2 1.0
Standing height 0.7 7.2 48.0 4.0 6.9 0.3 1.3 0.8 0.2 1.0 2.8 1.6 2.6 0.3 2.0 3.4 -0.9 2.7
Length of working week for main job 0.6 0.7 4.9 0.2 0.7 0.2 -2.2 0.1 0.1 0.5 0.4 0.4 0.5 -1.5 0.4 0.9 0.0 0.5
Exposure to tobacco smoke at home 2.2 2.5 4.9 -1.9 -1.2 1.3 -1.6 1.6 1.8 1.5 -2.2 -1.7 -1.6 -0.9 -1.6 -0.3 -1.8 -1.8
Breastfed as a baby 1.1 1.4 5.3 1.2 0.9 -0.9 0.1 -0.9 -0.9 -0.8 1.5 1.1 1.1 1.5 1.1 -2.3 0.7 1.2
Tense / ‘highly strung’ 0.3 0.4 1.1 -0.8 -0.6 -0.3 -0.3 -0.8 -0.6 -1.0 -0.5 0.6 0.3 -1.1 0.5 -0.9 0.4 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.8 -0.1 -0.1 -0.2 -1.3 -0.4 -0.3 -0.2 0.1 0.4 0.2 1.4 0.3 -0.9 -0.1 0.2
Hair/balding pattern: Pattern 4 0.0 0.1 0.3 -0.2 -0.1 -0.0 0.4 0.3 0.2 0.0 0.0 -0.3 -0.3 -0.0 -0.4 -0.4 -0.5 -0.3
Birth weight of first child 2.7 5.0 13.6 3.7 3.0 -1.3 2.3 -1.2 -1.4 -1.9 2.8 2.4 2.7 1.7 2.4 0.8 1.0 2.7
Peak expiratory flow (PEF) 3.0 7.0 11.0 2.5 3.0 -2.5 2.7 -2.3 -2.5 -2.7 2.2 3.3 3.3 1.5 3.3 -2.0 2.3 3.2
Pulse wave reflection index 1.6 2.0 4.1 2.0 1.4 -1.3 1.1 -1.1 -1.1 -1.4 1.8 1.7 1.8 0.8 1.7 -0.1 0.2 1.8
Ever highly irritable/argumentative for 2 days 0.9 1.0 4.1 -1.4 -2.0 -0.2 -0.3 0.3 0.3 -0.1 -1.3 -1.1 -1.4 0.4 -1.2 -0.1 -0.9 -1.4
Loud music exposure frequency 1.3 1.4 3.0 0.9 1.6 -1.7 -0.5 -1.5 -1.4 -1.3 0.2 1.3 1.1 -0.6 1.3 -0.0 1.5 1.1
Qualifications: O levels/GCSEs or equivalent 2.5 4.0 6.7 -1.4 -2.3 1.9 0.8 2.6 2.4 2.5 -1.9 -2.2 -2.1 -1.2 -2.3 1.1 -2.4 -2.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 1.3 -0.1 0.9 -0.2 -0.7 -0.9 -0.6 0.3 0.1 0.7 0.6 0.2 0.8 -1.1 0.9 0.6
Blood clot in the leg (DVT) 0.1 0.1 0.8 0.0 -0.2 0.9 0.2 0.1 0.2 0.4 0.3 -0.2 -0.1 0.1 -0.2 0.7 -0.5 -0.1
Medication: Paracetamol 0.3 0.5 4.0 -1.0 -0.8 -0.8 0.2 -0.5 -0.3 -0.0 -0.8 -0.1 -0.4 -0.0 -0.2 -2.0 0.6 -0.5
Headache pain in last month 0.3 0.5 1.7 -0.8 -0.5 -0.3 1.3 -0.6 -0.4 -0.4 -1.2 -0.1 -0.4 -1.1 -0.1 0.5 0.8 -0.4
Medication for cholesterol, blood pressure or diabetes 0.1 0.1 1.0 -0.4 0.4 -0.2 1.0 0.2 0.0 -0.2 -0.2 -0.0 -0.1 0.1 -0.1 -0.2 0.3 -0.1
Glaucoma (self-reported) 3.1 3.6 8.2 2.9 2.0 -1.1 0.4 -1.7 -1.8 -1.7 2.9 2.0 2.3 1.8 2.2 0.1 0.9 2.4
Gout (self-reported) 0.3 0.4 2.2 -0.7 -0.1 -0.5 0.2 -0.8 -0.7 -1.5 -0.7 0.2 -0.0 -0.7 0.2 -0.2 1.1 -0.1
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 2.2 -0.8 0.1 0.0 -0.3 0.1 0.4 0.2 -0.9 -0.4 -0.3 -1.5 -0.2 -0.1 0.0 -0.4
Medication: Amlodipine 0.2 0.3 1.1 -0.4 0.9 -1.0 -0.9 -0.6 -0.4 -0.3 -0.4 -0.3 -0.3 -0.7 -0.2 -0.4 0.6 -0.3
Medication: Ventolin 100micrograms inhaler 3.8 4.9 10.0 1.3 2.1 -3.1 1.0 -2.9 -2.9 -3.2 1.1 1.9 1.8 -0.2 2.1 -2.2 3.1 1.7
Birth weight 1.4 3.0 13.7 2.0 3.7 -0.2 1.7 0.2 0.1 0.1 1.9 1.6 2.0 0.1 1.6 2.7 0.5 1.9
Chronic bronchitis/emphysema (mother) 0.7 0.8 5.6 -0.4 0.1 -1.1 -2.4 -0.6 -0.5 -1.1 -0.2 -0.3 -0.3 -1.5 -0.2 0.7 0.7 -0.3
High blood pressure (siblings) 0.2 0.3 1.0 0.4 0.5 -0.1 -0.1 -0.6 -0.5 -0.5 0.1 0.6 0.5 -0.4 0.5 -1.0 0.7 0.4
Forced vital capacity (FVC), Best measure 1.4 5.1 16.7 3.1 4.1 -0.9 2.8 -0.4 -0.8 -0.5 2.5 2.6 3.1 0.8 2.7 -0.6 0.5 3.0
Body fat percentage 0.5 1.9 5.8 -2.2 -0.6 -0.7 -1.9 -0.8 -0.4 -1.0 -2.1 -0.6 -1.1 -2.4 -0.6 -1.7 1.0 -1.2
Leg fat percentage (right) 0.7 2.6 6.7 -2.5 -1.8 0.2 -2.6 0.3 0.5 -0.0 -2.3 -1.4 -1.8 -2.0 -1.5 -1.7 -0.1 -1.9
Arm fat-free mass (right) 0.2 1.2 12.0 1.0 3.5 0.1 1.0 -0.2 -0.4 -0.6 0.1 0.7 0.8 -0.9 0.7 0.9 0.4 0.7
Exposure to tobacco smoke outside home 0.5 0.7 5.6 -1.2 -1.0 -0.2 -0.0 -0.1 0.0 -0.6 -1.1 -0.3 -0.5 -2.4 -0.4 0.1 0.2 -0.6
Comparative body size at age 10 0.3 0.8 7.4 -0.9 0.0 -0.0 -0.8 0.8 0.6 0.2 -0.9 -0.6 -0.5 -2.7 -0.6 -0.0 -0.1 -0.6
Number of full brothers 0.4 0.5 1.2 -0.3 0.7 -1.0 -0.4 -0.9 -0.6 -1.0 -0.2 0.6 0.3 -0.8 0.5 -0.9 1.1 0.3
Worry too long after embarrassment 0.6 0.9 2.0 -1.1 -0.5 -0.9 1.2 -1.0 -0.9 -1.4 -1.3 -0.0 -0.3 -1.4 -0.0 -1.0 1.3 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 1.9 4.2 0.1 1.2 -2.0 -1.0 -1.7 -1.4 -1.3 0.5 1.8 1.6 -0.8 1.8 -0.5 1.9 1.5
Wheeze or whistling in the chest in last year 0.3 0.6 2.0 0.2 0.3 -1.1 -0.2 -0.9 -0.8 -0.9 0.2 0.6 0.5 -1.0 0.5 1.1 1.4 0.4
Number of children fathered 0.4 0.5 1.4 -0.4 -0.7 1.2 -0.7 0.8 0.9 0.4 -0.6 -0.7 -0.7 -0.2 -0.7 -0.3 -0.3 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 3.6 4.3 7.1 2.7 1.8 -2.0 0.3 -2.0 -2.1 -2.1 2.4 2.4 2.3 2.3 2.3 -1.5 1.3 2.3
Age at first live birth 1.4 2.5 5.6 -1.8 -1.9 1.2 1.0 1.9 1.7 1.5 -1.5 -1.6 -1.6 -0.2 -1.7 0.9 -2.4 -1.6
Pulse wave peak to peak time 1.5 1.7 4.8 -1.4 -1.5 1.1 0.4 1.2 1.1 0.9 -1.4 -1.5 -1.5 -0.9 -1.5 2.2 -0.4 -1.5
Health satisfaction 0.8 1.1 3.1 -1.6 -1.1 0.7 -1.0 0.3 0.4 0.4 -1.8 -1.0 -1.2 -1.5 -1.0 -0.0 0.2 -1.3
Shortness of breath walking on level ground 4.8 5.7 11.4 -3.1 -3.4 1.8 -1.0 2.0 2.0 1.8 -2.5 -2.9 -3.1 -0.7 -3.0 -0.8 -2.3 -3.1
Qualifications: College or University degree 1.0 3.3 5.8 1.5 2.1 -1.3 2.4 -1.7 -1.7 -2.0 1.5 2.1 2.2 0.6 2.2 -1.3 1.5 2.1
Eye problems/disorders: None of the above 0.4 0.5 2.0 -0.7 -0.8 0.7 0.4 0.3 0.7 0.6 -0.6 -0.5 -0.8 0.6 -0.7 -1.4 -0.4 -0.7
Mouth/teeth dental problems: Loose teeth 0.3 0.4 2.3 -0.3 0.3 -0.5 0.2 -1.0 -0.7 -0.6 -0.3 0.5 0.1 -0.3 0.3 -1.5 0.8 0.1
Emphysema/chronic bronchitis 0.6 0.7 1.0 1.0 0.7 -1.0 0.8 -0.9 -0.6 -0.6 0.9 1.0 0.9 0.4 0.9 -0.6 0.8 0.9
Medication for pain relief, constipation, heartburn 0.2 0.3 3.4 0.1 0.3 0.5 0.5 0.5 0.4 -0.3 0.2 -0.3 -0.2 -0.3 -0.3 1.8 -0.3 -0.1
Neck or shoulder pain in last month 1.5 2.1 4.7 -1.5 -2.0 0.8 -2.2 1.4 1.2 0.7 -1.2 -1.8 -1.8 -0.4 -1.8 0.4 -0.8 -1.8
Medication: Blood pressure 0.2 0.4 2.5 0.0 -0.2 0.8 -1.6 0.2 0.3 0.7 0.1 -0.3 -0.3 0.3 -0.2 -0.6 -1.0 -0.2
Angina (self-reported) 0.3 0.4 3.6 -0.2 0.4 -0.7 -0.2 -0.7 -0.5 -0.3 0.1 0.2 -0.1 0.8 0.1 -1.9 0.3 0.0
Migraine (self-reported) 2.6 3.2 5.1 -2.1 -2.1 1.7 0.5 1.7 1.8 1.6 -2.2 -2.0 -2.1 -2.3 -2.0 0.3 -0.8 -2.1
Medication: Ibuprofen 0.6 0.7 6.3 -0.0 -0.0 -0.6 0.5 -0.6 -0.6 -0.8 -0.7 0.6 0.4 -0.1 0.5 -2.5 1.1 0.2
Medication: Allopurinol 0.8 1.0 2.8 -1.7 -1.4 1.0 0.5 0.5 0.7 -0.3 -1.5 -1.1 -1.2 -0.7 -1.1 -0.0 -0.1 -1.3
Medication: Omeprazole 0.3 0.4 1.4 -0.9 -1.2 -0.4 -0.1 -0.6 -0.5 -0.3 -0.8 -0.5 -0.7 -0.3 -0.5 -0.6 0.4 -0.7
Medication: Seretide 50 evohaler 1.6 1.8 5.9 -0.8 0.6 -1.5 1.0 -1.9 -1.5 -1.7 -0.9 1.0 0.6 -0.7 0.9 -2.4 2.2 0.4
Mean time to correctly identify matches 3.3 6.3 14.4 1.2 2.9 -3.2 -0.6 -3.0 -3.0 -3.8 1.7 2.8 2.4 0.3 2.7 -1.8 2.8 2.4
Heart disease (mother) 0.4 0.5 1.2 -0.4 -0.6 1.1 -0.8 0.9 1.0 0.9 -0.4 -0.6 -0.6 -0.4 -0.6 0.7 -0.6 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.4 0.9 0.2 0.4 -0.5 0.4 0.2 1.2 1.0 0.4 0.6 0.9 0.4 -0.6 -1.0 0.7
Whole body fat mass 0.3 1.2 5.6 -1.6 0.6 -0.4 -1.1 -0.6 -0.3 -0.9 -1.8 -0.2 -0.7 -2.4 -0.3 -0.8 1.0 -0.8
Leg fat mass (right) 0.4 1.4 5.0 -1.9 -0.4 0.4 -1.4 0.2 0.4 -0.2 -2.0 -0.9 -1.2 -2.2 -0.9 -0.7 0.3 -1.3
Arm predicted mass (right) 0.2 1.1 10.9 1.1 3.3 0.2 1.1 -0.1 -0.3 -0.5 0.2 0.7 0.7 -0.6 0.6 0.9 0.2 0.7
Pulse rate, automated reading 1.8 5.8 9.6 -3.1 -2.5 2.7 -1.3 2.7 2.9 1.7 -2.9 -2.4 -2.6 -2.1 -2.6 0.3 -2.0 -2.6
Alcohol intake frequency. 0.2 0.6 1.8 -0.2 -0.5 -0.1 1.2 -0.9 -0.8 -1.2 -0.9 0.1 -0.1 -1.4 0.1 0.1 1.1 -0.2
Comparative height size at age 10 0.6 3.1 25.0 2.5 5.0 0.7 -0.1 1.2 0.8 1.2 1.6 0.3 1.1 0.6 0.6 1.5 -1.8 1.1
Number of full sisters 1.1 1.4 3.5 -0.9 -1.4 1.2 1.9 1.0 1.1 0.7 -1.0 -1.4 -1.3 -0.5 -1.2 1.1 -1.1 -1.2
Suffer from ‘nerves’ 0.3 0.5 2.0 0.8 0.9 -0.4 -0.1 -0.2 -0.4 -0.4 1.0 0.7 0.7 1.4 0.6 -0.2 0.1 0.8
Overall health rating 1.9 4.1 12.7 -3.5 -2.7 0.4 -1.9 -0.2 0.3 -0.4 -3.6 -1.8 -2.4 -2.2 -1.8 -0.8 0.9 -2.6
Chest pain or discomfort 0.5 0.8 7.0 0.2 1.3 -0.6 -2.6 -0.6 -0.4 0.2 0.2 0.2 0.3 -0.7 0.4 1.0 0.4 0.3
Had major operations 1.0 1.2 3.7 1.2 0.3 -1.9 0.2 -1.5 -1.6 -1.1 1.1 1.3 0.9 0.4 1.0 -0.3 0.4 1.0
Age at last live birth 1.0 1.4 2.3 -1.4 -1.2 1.2 1.3 1.5 1.2 1.4 -1.1 -1.0 -1.0 -0.6 -1.1 1.5 -1.3 -1.0
Family relationship satisfaction 0.4 0.5 3.4 -0.3 -0.1 0.1 -1.5 -0.0 -0.1 -0.7 -0.4 0.1 -0.1 -1.8 0.1 0.8 0.2 -0.1
Leg pain on walking 1.0 1.3 3.6 -1.4 -1.9 1.0 -1.1 0.7 0.7 0.4 -1.4 -1.1 -1.3 -0.5 -1.2 -0.9 -1.3 -1.3
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 1.4 0.1 0.2 0.1 0.4 -0.1 0.1 -0.4 -0.4 0.6 0.3 -0.7 0.3 0.4 1.2 0.2
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.4 -0.1 1.2 -0.2 1.1 -0.8 -0.8 -0.2 0.3 0.6 0.7 -0.2 0.8 -0.3 0.8 0.6
Illness, injury, bereavement, stress in last 2 years 3.0 3.6 8.5 2.4 2.3 -1.0 1.0 -1.3 -1.7 -1.0 2.5 2.0 2.2 2.9 2.0 -0.8 1.4 2.3
Medication: Aspirin 1.0 1.3 7.0 -0.4 -0.9 0.5 -2.7 0.9 1.0 1.9 -0.2 -0.7 -0.7 -0.5 -0.8 1.6 -1.3 -0.7
Supplements: Vitamin C 5.4 6.4 9.7 2.5 2.7 -2.7 1.3 -3.1 -3.0 -2.8 2.4 2.9 2.7 -0.4 2.9 -1.4 2.7 2.7
Knee pain experienced in last month 1.1 1.8 4.7 -2.0 -2.0 0.4 -2.2 0.3 0.4 0.0 -1.5 -1.4 -1.5 -1.6 -1.3 0.3 -0.4 -1.6
Hypertension (Self-reported) 0.7 1.9 3.9 -1.7 -1.3 0.7 -0.8 0.7 1.0 1.0 -1.9 -1.7 -2.0 -0.2 -1.7 -1.5 -1.0 -1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.8 3.0 -1.7 -1.3 1.4 -1.0 1.2 1.3 1.2 -1.7 -1.6 -1.5 -0.5 -1.4 0.4 -1.7 -1.5
Illnesses of father: Heart disease 1.4 2.0 4.3 2.0 2.1 -0.5 -0.5 -0.6 -0.6 -0.5 1.9 1.5 1.7 1.6 1.6 1.2 0.7 1.8
Illnesses of siblings: Diabetes 1.7 2.0 5.2 -2.1 -2.3 -0.1 -1.3 0.8 1.2 0.7 -2.1 -1.4 -1.8 -0.7 -1.6 -0.9 0.3 -1.8
Smoking status: Previous 0.5 0.7 1.6 -1.2 -0.2 0.2 -0.3 0.7 0.8 1.2 -1.3 -0.8 -0.8 -1.0 -0.7 0.6 -1.2 -0.8
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 3.5 0.8 1.9 1.2 1.4 0.8 0.7 1.0 0.4 0.4 0.7 0.5 0.5 1.3 -0.6 0.7
Whole body fat-free mass 0.3 1.5 13.9 1.1 3.7 0.3 1.3 0.0 -0.2 -0.5 0.2 0.8 0.9 -0.8 0.8 1.5 0.4 0.8
Leg fat-free mass (right) 0.2 1.3 9.5 0.1 3.1 0.0 1.6 -0.4 -0.4 -1.1 -0.7 0.7 0.5 -1.6 0.6 1.1 1.0 0.4
Arm fat percentage (left) 0.5 2.0 5.0 -2.2 -0.8 -0.8 -1.5 -1.0 -0.6 -1.3 -2.2 -0.4 -1.1 -2.2 -0.5 -1.9 1.3 -1.2
Average weekly red wine intake 0.1 0.2 0.9 0.2 -0.2 0.9 -0.2 0.5 0.5 0.8 0.5 0.1 0.3 -0.2 0.2 0.5 -0.1 0.3
Handedness (chirality/laterality): Left-handed 0.4 0.5 2.3 -0.6 -1.3 -0.3 -0.3 0.1 0.0 0.1 -0.2 -0.2 -0.4 -1.3 -0.3 1.5 -0.4 -0.3
Mood swings 0.7 1.2 2.5 -1.4 -0.6 -1.6 -1.0 -1.5 -1.2 -1.6 -1.2 0.2 -0.4 -1.3 0.0 -1.1 1.3 -0.5
Loneliness, isolation 0.5 0.7 1.8 0.4 -0.1 -1.1 -0.5 -1.3 -1.3 -1.4 0.1 0.7 0.3 -0.6 0.5 -1.2 1.0 0.3
Long-standing illness, disability or infirmity 0.6 1.0 2.8 -1.5 -0.3 0.8 -0.7 0.4 0.8 0.6 -1.6 -0.9 -1.0 -1.7 -0.8 0.8 -0.9 -1.0
Ever had bowel cancer screening 0.3 0.4 3.2 0.7 -0.0 -0.5 0.5 -0.2 -0.4 -0.4 0.6 0.1 0.1 0.5 0.0 -1.8 -0.5 0.2
Diabetes diagnosed by doctor 3.2 5.3 9.1 -2.9 -3.0 1.5 -2.3 2.1 2.2 2.0 -2.5 -2.5 -2.6 -1.8 -2.5 1.9 -1.3 -2.6
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 4.8 -1.3 -1.4 2.2 -0.3 1.2 1.3 1.6 -0.9 -1.3 -1.2 -0.7 -1.2 1.2 -1.5 -1.2
Friendships satisfaction 0.6 0.8 1.7 -1.3 -0.4 0.9 -1.0 0.6 0.8 0.1 -1.3 -0.8 -1.0 -1.2 -0.9 -0.3 -0.8 -1.0
Qualifications: nursing, teaching 0.4 0.7 4.2 -0.5 0.1 -0.9 1.2 -0.9 -0.9 -0.9 -0.8 0.1 0.1 -2.0 0.3 0.2 0.2 0.0
Commuting to job workplace: Walk 0.8 0.8 2.8 -0.5 -0.3 -1.2 -0.4 -1.1 -0.8 -1.5 -1.1 0.5 -0.0 -1.7 0.3 0.6 1.3 -0.1
Eye problems/disorders: Cataract 0.4 0.5 3.1 -0.5 -0.2 0.6 0.3 0.6 0.4 0.3 -0.6 -0.5 -0.4 -1.2 -0.5 1.8 0.3 -0.4
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 2.0 0.4 0.3 -0.7 0.1 -0.8 -0.5 -0.4 0.5 0.7 0.6 0.2 0.7 -1.4 0.9 0.6
Medication for cholesterol 1.7 2.5 4.7 1.6 1.7 -1.3 0.5 -1.4 -1.5 -1.1 2.1 2.1 2.2 -0.5 2.0 -0.6 1.5 2.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.6 -0.2 0.2 -0.5 0.2 -0.8 -0.8 -0.6 -0.4 0.4 0.1 0.1 0.3 -1.3 1.0 0.1
Back pain experienced in last month 2.2 3.2 4.8 -1.4 -1.7 1.9 -2.1 1.8 1.8 1.8 -1.5 -2.1 -2.1 -1.2 -2.2 -0.0 -1.9 -2.1
Mineral and other dietary supplements 2.2 3.0 6.1 -1.2 -2.0 2.2 0.5 2.0 2.0 1.9 -1.1 -1.9 -1.7 -0.0 -1.8 2.5 -1.7 -1.6
Breast cancer (self-reported) 9.8 11.7 22.5 -4.1 -4.7 3.2 0.3 3.2 3.6 2.7 -4.0 -3.8 -4.2 -1.5 -4.1 -0.8 -3.2 -4.2
Asthma (self-reported) 0.3 0.7 2.8 -1.3 -1.1 -0.6 -0.4 -0.0 0.2 0.2 -0.9 -0.7 -0.9 -0.1 -0.7 -1.7 0.6 -0.9
Osteoporosis (self-reported) 1.3 1.7 3.0 1.0 1.4 -1.5 1.4 -1.5 -1.3 -0.9 0.9 1.7 1.6 -0.2 1.7 -0.6 1.1 1.6
Osteoarthritis (self-reported) 0.7 0.9 5.2 -0.5 0.1 -1.2 -1.6 -0.8 -0.7 -0.8 -0.7 -0.1 -0.3 -1.3 -0.2 -2.3 0.8 -0.4
Medication: Aspirin 1.5 2.0 6.9 -0.8 -1.3 1.1 -2.6 1.4 1.6 2.1 -0.5 -1.1 -1.1 -0.1 -1.2 1.6 -1.7 -1.1
Medication: Gliclazide 1.0 1.1 3.1 -1.5 -1.2 -0.1 -1.2 0.2 0.4 0.2 -1.4 -1.2 -1.2 -1.8 -1.1 0.9 0.2 -1.3
Illnesses of father: None of the above (group 1) 0.3 0.4 1.5 0.6 0.5 -1.2 -0.0 -0.7 -1.0 -0.5 0.5 0.4 0.5 0.2 0.5 -0.4 -0.1 0.5
Smoking status: Current 2.4 3.7 7.5 1.5 1.9 -1.4 1.0 -2.2 -2.1 -2.6 1.5 2.4 2.2 -0.7 2.4 0.1 2.7 2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.2 4.0 1.8 1.6 -1.0 1.6 -0.8 -0.9 -0.8 1.7 2.0 2.0 1.6 1.8 -1.3 1.0 1.9
Whole body water mass 0.3 1.7 14.7 1.3 3.8 0.1 1.3 -0.2 -0.3 -0.7 0.3 0.9 1.0 -0.8 0.9 1.4 0.5 0.9
Leg predicted mass (right) 0.2 1.3 9.4 0.1 3.1 -0.0 1.6 -0.4 -0.4 -1.1 -0.7 0.7 0.5 -1.6 0.6 1.1 1.0 0.4
Arm fat mass (left) 0.3 1.3 4.6 -1.7 0.3 -0.7 -0.7 -0.9 -0.6 -1.3 -1.9 -0.1 -0.7 -2.2 -0.3 -1.4 1.2 -0.9
Number of self-reported non-cancer illnesses 1.2 2.0 7.1 -2.7 -1.6 0.2 -0.8 0.0 0.5 0.2 -2.4 -1.3 -1.7 -1.3 -1.3 -1.8 -0.0 -1.8
Average weekly champagne plus white wine intake 1.0 1.4 4.0 2.0 1.7 0.4 -1.4 0.4 0.2 0.5 1.9 1.0 1.4 1.2 1.1 -0.1 -0.9 1.4
Miserableness 0.5 0.8 2.5 -1.0 -0.2 -1.6 -0.8 -1.2 -1.0 -1.2 -1.2 0.1 -0.4 -0.8 -0.0 -0.0 1.3 -0.5
Guilty feelings 0.6 0.9 2.7 -1.3 -0.4 -1.6 -1.1 -1.0 -0.9 -1.2 -1.0 -0.2 -0.6 -0.1 -0.3 -1.4 1.1 -0.7
Wears glasses or contact lenses 5.3 6.1 10.8 2.5 3.1 -3.3 -0.3 -2.9 -3.0 -2.5 2.3 2.6 2.7 0.9 2.8 -0.9 2.4 2.6
Ever taken oral contraceptive pill 0.4 0.4 2.8 -1.7 -0.5 0.2 -0.4 0.4 0.5 0.6 -1.0 -0.4 -0.7 0.0 -0.6 0.2 -0.0 -0.7
Hearing aid user 0.6 0.6 2.7 1.1 -0.4 0.2 1.6 -0.1 0.1 0.5 0.9 0.1 0.0 1.5 0.0 -0.2 -1.4 0.2
Mother’s age at death 0.1 0.1 0.6 0.1 0.3 0.2 0.5 -0.5 -0.5 -0.4 0.4 0.2 0.3 0.2 0.3 -0.0 0.8 0.3
Financial situation satisfaction 1.4 1.8 5.9 -2.2 -2.0 0.6 0.0 0.3 0.4 -0.0 -2.4 -1.3 -1.7 -1.0 -1.4 0.4 -0.1 -1.8
Tinnitus: Yes, now most or all of the time 0.6 0.8 2.7 0.8 1.2 -0.3 -1.0 0.0 -0.1 0.4 1.2 0.5 0.7 1.6 0.6 -1.2 -0.7 0.8
Commuting to job workplace: Public transport 1.8 2.1 4.2 2.1 1.6 -1.1 1.2 -1.4 -1.4 -1.2 1.7 1.8 1.6 1.4 1.6 0.1 0.7 1.7
Eye problems/disorders: Glaucoma 1.7 2.0 6.5 2.5 1.4 -0.8 -1.0 -0.6 -0.8 -0.7 2.5 1.4 1.7 1.3 1.5 0.1 -0.1 1.9
Medication: Blood pressure 1.0 1.9 4.3 -2.1 -1.4 0.6 0.1 0.6 0.9 0.7 -2.0 -1.7 -2.1 0.3 -1.8 0.8 -0.2 -2.0
Pain type(s) experienced in last month: Hip pain 1.3 1.6 5.0 -2.1 -1.2 0.1 -0.7 0.1 0.4 -0.3 -2.2 -1.3 -1.5 -1.8 -1.2 -0.9 0.5 -1.6
Supplements: Fish oil (including cod liver oil) 2.8 3.7 6.2 1.5 2.0 -2.2 -0.3 -2.1 -2.0 -2.2 1.5 2.3 2.1 0.7 2.2 -2.5 1.9 2.0
High cholesterol (Self-reported) 1.2 2.1 3.0 -1.0 -1.7 1.7 -0.6 1.6 1.7 1.7 -1.2 -1.7 -1.7 -0.1 -1.7 1.3 -1.5 -1.6
Medication: Bendroflumethiazide 0.5 0.7 2.0 -1.4 -0.3 -0.1 -0.7 -0.1 0.0 -0.6 -1.4 -0.7 -1.0 -1.4 -0.8 0.4 0.0 -1.1
Medication: Paracetamol 0.7 1.0 8.9 -1.5 -0.9 -0.9 -0.9 -0.3 -0.1 0.1 -0.9 -0.1 -0.5 -0.2 -0.3 -3.0 0.4 -0.5
Medication: Lisinopril 0.6 0.8 3.5 -1.9 -1.1 0.2 -0.4 0.3 0.3 0.5 -1.4 -0.9 -1.1 -0.5 -0.9 -0.5 0.1 -1.1
Medication: Atorvastatin 1.0 1.3 3.2 0.1 -0.8 1.3 -1.3 1.1 1.2 1.6 0.0 -1.0 -0.9 0.7 -0.9 1.8 -1.8 -0.7
Illnesses of father: High blood pressure 0.4 0.5 1.3 -1.2 -0.9 0.9 -0.3 0.6 0.9 0.4 -0.9 -0.5 -0.6 -0.8 -0.5 0.3 -0.4 -0.6
Alcohol drinker status: Never 1.0 1.2 2.5 1.0 0.5 -1.3 0.1 -1.4 -1.6 -1.6 0.7 1.3 1.1 -0.5 1.1 0.3 1.3 1.0
Ever smoked 1.2 2.2 3.9 1.1 2.0 -1.2 1.2 -1.8 -1.6 -1.4 0.9 1.9 1.8 -0.1 1.9 -0.1 1.5 1.8
Basal metabolic rate 0.2 1.1 10.8 0.6 3.3 0.2 1.0 -0.1 -0.2 -0.6 -0.3 0.6 0.6 -1.3 0.6 1.1 0.5 0.5
Leg fat percentage (left) 0.9 3.2 8.4 -2.9 -1.9 0.1 -2.5 0.2 0.5 -0.2 -2.7 -1.4 -2.0 -2.4 -1.5 -1.9 0.2 -2.1
Arm fat-free mass (left) 0.2 1.0 10.3 0.9 3.2 0.1 0.5 -0.1 -0.3 -0.6 -0.0 0.6 0.6 -1.2 0.6 1.1 0.1 0.5
Number of operations (self-reported) 0.7 1.0 2.2 1.3 0.1 -1.1 -0.5 -1.5 -1.4 -0.7 1.4 1.2 1.0 0.6 1.1 -0.7 0.3 1.1
Average weekly beer plus cider intake 0.3 0.4 3.1 -0.6 -0.7 -0.3 0.8 -0.4 -0.5 -0.5 -1.0 0.2 0.0 0.0 0.2 1.8 0.0 -0.0
Irritability 0.9 1.6 5.5 -2.1 -1.3 0.8 -0.6 0.0 0.5 -0.1 -2.3 -0.5 -1.1 -2.2 -0.7 1.1 1.1 -1.2
Risk taking 1.5 2.2 3.6 1.4 1.7 -1.2 1.5 -1.4 -1.4 -1.4 1.6 1.9 1.9 0.9 1.9 -0.4 1.2 1.8
Ever had prostate specific antigen (PSA) test 0.8 0.9 2.1 1.0 0.2 -1.4 0.7 -1.2 -1.3 -1.4 0.9 1.0 0.9 0.5 0.9 0.1 0.6 0.9
Fractured/broken bones in last 5 years 0.3 0.4 2.0 -0.3 -0.2 0.3 -0.7 0.6 0.5 0.5 0.2 -0.5 -0.4 1.1 -0.5 -0.6 -1.4 -0.3
Age started oral contraceptive pill 0.6 0.8 1.8 -1.0 -0.4 -0.5 -1.0 1.0 1.1 0.8 -0.8 -1.0 -1.0 -0.5 -1.0 0.2 -1.4 -1.0
Diastolic blood pressure, automated reading 0.2 0.7 2.2 -0.8 -0.7 1.5 -0.0 0.9 0.9 0.5 -0.6 -1.0 -1.0 0.6 -1.0 -0.2 -0.4 -0.9
Ever depressed for a whole week 0.3 0.4 1.9 0.6 0.5 -0.2 0.7 -0.7 -0.9 -1.4 0.0 0.7 0.5 0.1 0.6 -0.3 0.0 0.4
Unable to work because of sickness or disability 1.9 2.4 4.0 -2.0 -2.0 0.9 -1.9 0.9 1.0 0.8 -1.8 -1.6 -1.9 -1.7 -1.7 1.6 -0.2 -1.9
Commuting to job workplace: Cycle 0.4 0.5 4.1 0.1 0.1 -0.7 0.6 -0.6 -0.6 -0.8 -0.1 0.4 0.1 -1.0 0.2 2.0 0.7 0.1
Myopia 0.5 0.7 2.9 -0.4 -0.4 -0.8 1.7 -0.9 -0.9 -1.1 -0.3 0.1 -0.2 1.1 0.0 -1.1 1.1 -0.2
Vascular/heart problems diagnosed by doctor 1.1 3.1 6.5 2.4 2.0 -0.9 0.4 -1.1 -1.3 -1.3 2.5 2.2 2.5 0.5 2.2 1.0 1.2 2.5
Cholesterol lowering medication 2.5 3.6 6.2 -1.3 -1.6 1.6 -2.0 2.1 2.2 2.2 -1.6 -2.1 -2.1 -0.1 -2.1 2.0 -2.5 -1.9
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 1.2 -0.8 -1.1 -0.5 -0.2 -0.7 -0.6 -0.6 -0.7 -0.5 -0.7 -0.3 -0.5 -0.6 0.6 -0.7
Pain experienced in last month 0.1 0.2 0.7 0.5 0.6 0.4 0.5 0.4 0.4 0.5 0.8 0.2 0.3 0.5 0.2 -0.0 -0.2 0.4
Supplements: Calcium 1.6 1.7 4.4 1.1 1.8 -1.2 0.0 -1.3 -1.1 -1.1 1.1 1.4 1.4 0.6 1.4 -2.1 1.5 1.3
Basal cell carcinoma (self-reported) 2.5 3.0 8.4 -1.1 -1.2 2.0 -1.6 2.6 2.4 2.4 -0.8 -1.6 -1.3 -0.3 -1.6 1.0 -2.9 -1.2
Heart attack/myocardial infarction (self-reported) 0.1 0.2 0.6 -0.2 -0.4 0.1 0.6 0.2 0.2 0.6 -0.4 -0.4 -0.4 0.6 -0.4 0.8 -0.4 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.9 0.1 -0.3 1.0 0.6 0.1 0.2 0.4 0.4 -0.3 -0.1 0.4 -0.1 0.7 -0.4 -0.0
Heart disease (siblings) 0.9 1.1 3.3 -1.7 -1.2 0.1 -1.8 0.7 0.8 0.5 -1.3 -0.9 -1.2 -1.1 -1.0 -0.3 -0.0 -1.2
Alcohol drinker status: Previous 0.3 0.4 1.1 -0.5 -0.7 1.0 -0.7 0.6 0.9 0.5 -0.5 -0.4 -0.3 -1.1 -0.3 -0.1 -0.6 -0.3
Pack years of smoking 0.6 0.9 2.5 -1.2 -1.5 0.5 -0.7 0.4 0.6 0.2 -1.3 -0.9 -1.0 -1.6 -0.8 0.1 -0.8 -1.0
Impedance of whole body 0.1 0.6 2.2 0.3 -0.9 0.1 -1.3 0.9 0.8 1.5 0.6 -0.7 -0.2 0.0 -0.4 0.1 -1.1 -0.1
Leg fat mass (left) 0.4 1.5 5.2 -2.0 -0.3 0.3 -1.3 0.1 0.3 -0.3 -2.2 -0.8 -1.2 -2.3 -0.9 -0.9 0.4 -1.4
Arm predicted mass (left) 0.2 1.0 9.7 0.9 3.1 0.1 0.4 0.0 -0.2 -0.6 0.0 0.5 0.6 -1.1 0.5 1.2 0.1 0.5