[Hub]/) : Traits : Standing height :

chr15:39,530,508-42,749,023

Best TWAS P=8.28e-24 · Best GWAS P=2.07e-17 conditioned to 0.246

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EXD1 0.04 0.04 lasso 3 0.04 8.1e-06 -6.8 7.2 6.3e-13 -0.94 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex NDUFAF1 0.14 0.16 bslmm 304 0.19 6.6e-23 -5.2 6.1 9.5e-10 -0.44 0.91 0.09 FALSE
3 CommonMind Brain Pre-frontal Cortex NUSAP1 0.20 0.24 bslmm 311 0.24 4.6e-29 -7.3 -7.4 1.4e-13 0.58 0.86 0.14 FALSE
4 GTEx Adipose Subcutaneous OIP5-AS1 0.21 0.23 lasso 5 0.26 3.7e-21 -5.8 -7.0 2.1e-12 0.59 0.46 0.54 FALSE
5 GTEx Adipose Visceral Omentum OIP5-AS1 0.23 0.16 lasso 10 0.11 2.8e-06 -7.8 -8.2 2.1e-16 0.66 0.48 0.51 FALSE
6 GTEx Adrenal Gland OIP5-AS1 0.17 0.16 lasso 3 0.16 2.6e-06 -7.4 -7.7 1.3e-14 0.56 0.58 0.29 FALSE
7 GTEx Artery Aorta EIF2AK4 0.31 0.08 enet 29 0.17 1.8e-09 -2.7 5.4 7.4e-08 0.05 0.16 0.21 TRUE
8 GTEx Artery Aorta OIP5-AS1 0.16 0.21 enet 26 0.23 5.2e-13 -5.8 -7.5 4.8e-14 0.68 0.93 0.07 FALSE
9 GTEx Artery Coronary OIP5-AS1 0.12 0.13 lasso 2 0.14 2.3e-05 -7.8 -7.7 1.7e-14 0.60 0.31 0.54 FALSE
10 GTEx Artery Tibial OIP5-AS1 0.16 0.23 lasso 4 0.24 3.6e-19 -5.8 -6.9 5.6e-12 0.59 0.72 0.28 FALSE
11 GTEx Brain Caudate basal ganglia NUSAP1 0.31 0.38 lasso 9 0.40 1.1e-12 -6.6 -6.9 6.1e-12 0.55 0.80 0.20 FALSE
12 GTEx Brain Cerebellar Hemisphere NUSAP1 0.24 0.31 lasso 6 0.22 2.0e-06 -7.4 -7.8 7.5e-15 0.64 0.30 0.67 FALSE
13 GTEx Brain Cerebellar Hemisphere NDUFAF1 0.20 0.23 lasso 6 0.22 2.2e-06 -6.6 7.3 2.5e-13 -0.58 0.56 0.31 FALSE
14 GTEx Brain Cerebellum OIP5 0.16 0.09 lasso 4 0.16 1.8e-05 -7.4 -7.1 1.6e-12 0.68 0.16 0.46 FALSE
15 GTEx Brain Cerebellum NUSAP1 0.22 0.23 enet 18 0.22 3.7e-07 -6.6 -7.1 1.7e-12 0.59 0.53 0.43 FALSE
16 GTEx Brain Cerebellum NDUFAF1 0.24 0.26 lasso 8 0.20 1.1e-06 -6.7 6.8 1.1e-11 -0.57 0.52 0.46 FALSE
17 GTEx Brain Cortex NUSAP1 0.43 0.25 enet 27 0.26 8.7e-08 -6.6 -6.0 2.5e-09 0.54 0.73 0.26 FALSE
18 GTEx Brain Cortex NDUFAF1 0.40 0.37 enet 22 0.36 7.0e-11 -5.0 5.3 1.2e-07 -0.49 0.68 0.32 FALSE
19 GTEx Brain Frontal Cortex BA9 NUSAP1 0.39 0.42 enet 22 0.42 2.0e-12 -6.6 -6.7 2.1e-11 0.66 0.69 0.31 FALSE
20 GTEx Brain Frontal Cortex BA9 NDUFAF1 0.55 0.37 lasso 8 0.40 1.6e-11 -7.8 7.6 2.4e-14 -0.61 0.48 0.52 FALSE
21 GTEx Brain Hippocampus NUSAP1 0.30 0.25 enet 14 0.26 1.0e-06 -7.4 -7.3 2.8e-13 0.65 0.19 0.59 FALSE
22 GTEx Brain Hypothalamus NUSAP1 0.26 0.36 lasso 4 0.27 5.6e-07 -4.0 -5.1 2.8e-07 0.45 0.70 0.16 FALSE
23 GTEx Brain Hypothalamus NDUFAF1 0.24 0.12 lasso 5 0.13 5.9e-04 -6.2 6.8 9.2e-12 -0.54 0.20 0.24 FALSE
24 GTEx Brain Nucleus accumbens basal ganglia NUSAP1 0.36 0.32 lasso 6 0.26 1.5e-07 -7.8 -7.5 5.6e-14 0.64 0.49 0.50 FALSE
25 GTEx Brain Nucleus accumbens basal ganglia NDUFAF1 0.12 0.11 lasso 6 0.10 9.7e-04 -6.6 6.3 2.4e-10 -0.52 0.23 0.38 FALSE
26 GTEx Brain Putamen basal ganglia NUSAP1 0.38 0.30 lasso 20 0.34 9.1e-09 -6.6 -7.1 9.7e-13 0.51 0.69 0.29 FALSE
27 GTEx Breast Mammary Tissue OIP5-AS1 0.20 0.24 lasso 7 0.22 1.8e-11 -5.8 -6.3 2.3e-10 0.56 0.99 0.01 FALSE
28 GTEx Breast Mammary Tissue (Female) OIP5-AS1 0.28 0.31 lasso 3 0.29 3.0e-09 -5.8 -5.9 2.7e-09 0.56 0.96 0.03 FALSE
29 GTEx Cells EBV-transformed lymphocytes NDUFAF1 0.35 0.46 enet 14 0.51 3.1e-19 -6.6 6.7 2.4e-11 -0.57 0.98 0.02 FALSE
30 GTEx Cells EBV-transformed lymphocytes OIP5-AS1 0.21 0.12 lasso 7 0.10 3.2e-04 -7.8 -6.8 1.0e-11 0.61 0.23 0.21 FALSE
31 GTEx Cells Transformed fibroblasts NDUFAF1 0.26 0.15 lasso 8 0.20 2.8e-15 -6.1 6.2 6.8e-10 -0.51 0.89 0.11 FALSE
32 GTEx Cells Transformed fibroblasts CHP1 0.13 0.11 lasso 6 0.11 2.1e-08 -5.2 5.2 2.3e-07 -0.68 0.97 0.03 FALSE
33 GTEx Cells Transformed fibroblasts OIP5-AS1 0.28 0.32 lasso 2 0.32 3.5e-24 -7.8 -7.8 5.8e-15 0.61 0.23 0.77 FALSE
34 GTEx Colon Sigmoid NDUFAF1 0.15 0.06 lasso 4 0.06 5.2e-03 -4.4 6.1 1.3e-09 -0.57 0.21 0.48 FALSE
35 GTEx Colon Sigmoid OIP5-AS1 0.21 0.27 lasso 3 0.25 3.3e-09 -7.8 -7.7 1.3e-14 0.61 0.49 0.51 FALSE
36 GTEx Colon Transverse OIP5-AS1 0.13 0.14 lasso 5 0.15 1.8e-07 -7.8 -7.5 6.0e-14 0.59 0.58 0.41 FALSE
37 GTEx Esophagus Gastroesophageal Junction OIP5-AS1 0.18 0.10 lasso 7 0.11 8.9e-05 -7.8 -7.6 3.7e-14 0.67 0.40 0.45 FALSE
38 GTEx Esophagus Mucosa NDUFAF1 0.25 0.18 enet 26 0.24 4.3e-16 -4.4 6.2 4.6e-10 -0.54 1.00 0.00 FALSE
39 GTEx Esophagus Mucosa CHP1 0.19 0.10 lasso 7 0.09 1.4e-06 -6.7 7.6 4.2e-14 -0.83 0.55 0.45 FALSE
40 GTEx Esophagus Mucosa OIP5-AS1 0.20 0.22 lasso 6 0.20 1.7e-13 -6.6 -6.9 5.8e-12 0.52 0.90 0.10 FALSE
41 GTEx Esophagus Muscularis NDUFAF1 0.24 0.23 lasso 5 0.28 2.8e-17 -7.8 7.0 1.8e-12 -0.55 0.35 0.65 FALSE
42 GTEx Esophagus Muscularis OIP5-AS1 0.24 0.24 enet 19 0.28 4.6e-17 -7.8 -6.8 8.6e-12 0.60 0.46 0.54 FALSE
43 GTEx Heart Atrial Appendage NDUFAF1 0.36 0.28 enet 24 0.34 9.5e-16 -6.7 6.7 2.2e-11 -0.55 0.92 0.08 FALSE
44 GTEx Heart Left Ventricle NDUFAF1 0.49 0.62 lasso 8 0.62 2.0e-41 -6.7 6.7 2.0e-11 -0.54 0.99 0.01 FALSE
45 GTEx Lung OIP5-AS1 0.09 0.08 enet 14 0.12 2.8e-09 -6.5 -7.8 8.4e-15 0.82 0.40 0.60 FALSE
46 GTEx Muscle Skeletal NDUFAF1 0.44 0.56 enet 31 0.60 3.0e-73 -6.6 7.6 3.0e-14 -0.63 1.00 0.00 FALSE
47 GTEx Nerve Tibial OIP5 0.07 0.08 lasso 2 0.05 1.6e-04 -5.4 -5.5 3.1e-08 0.69 0.56 0.36 FALSE
48 GTEx Nerve Tibial NUSAP1 0.15 0.09 enet 10 0.15 9.8e-11 -7.4 -7.4 1.1e-13 0.77 0.55 0.45 FALSE
49 GTEx Nerve Tibial NDUFAF1 0.36 0.43 lasso 6 0.43 8.0e-33 -6.6 -6.6 3.5e-11 0.52 0.98 0.02 FALSE
50 GTEx Nerve Tibial OIP5-AS1 0.20 0.22 enet 21 0.26 1.3e-18 -7.8 -6.9 3.7e-12 0.60 0.35 0.65 FALSE
51 GTEx Pancreas NDUFAF1 0.41 0.39 enet 20 0.42 2.7e-19 -6.6 -7.2 4.2e-13 0.56 0.97 0.03 FALSE
52 GTEx Pancreas OIP5-AS1 0.07 0.13 lasso 2 0.10 7.5e-05 -5.8 -6.2 4.5e-10 0.52 0.45 0.30 FALSE
53 GTEx Pituitary NUSAP1 0.16 0.12 lasso 2 0.16 7.4e-05 -6.6 -6.8 1.0e-11 0.56 0.28 0.46 FALSE
54 GTEx Prostate NDUFAF1 0.30 0.12 lasso 2 0.14 2.7e-04 -6.1 -6.2 4.9e-10 0.64 0.26 0.12 FALSE
55 GTEx Skin Not Sun Exposed Suprapubic OIP5-AS1 0.17 0.19 enet 17 0.22 4.3e-12 -7.4 -7.8 5.7e-15 0.65 0.61 0.39 FALSE
56 GTEx Skin Sun Exposed Lower leg CHP1 0.06 0.04 enet 9 0.04 3.1e-04 -6.5 6.2 5.0e-10 -0.80 0.17 0.67 FALSE
57 GTEx Skin Sun Exposed Lower leg OIP5-AS1 0.13 0.17 lasso 3 0.23 5.0e-19 -5.8 -6.7 1.6e-11 0.60 0.74 0.26 FALSE
58 GTEx Testis OIP5-AS1 0.14 0.16 lasso 1 0.14 8.6e-07 -5.8 -5.8 8.5e-09 0.49 0.80 0.03 FALSE
59 GTEx Thyroid OIP5 0.06 0.03 lasso 5 0.02 1.1e-02 -7.4 -6.6 3.6e-11 0.55 0.40 0.18 FALSE
60 GTEx Thyroid NDUFAF1 0.25 0.21 lasso 6 0.22 9.3e-17 -6.4 -6.1 1.3e-09 0.56 0.97 0.03 FALSE
61 GTEx Thyroid OIP5-AS1 0.20 0.19 lasso 8 0.20 4.1e-15 -5.8 -5.9 3.0e-09 0.58 0.99 0.01 FALSE
62 METSIM Adipose NDUFAF1 0.08 0.09 bslmm 296 0.09 2.4e-13 -6.2 5.6 2.3e-08 -0.37 1.00 0.00 FALSE
63 METSIM Adipose NUSAP1 0.03 0.03 lasso 6 0.02 4.2e-04 -7.3 -7.3 2.1e-13 0.55 0.48 0.31 FALSE
64 NTR Blood INO80 0.02 0.02 enet 8 0.03 2.8e-09 -6.7 6.3 3.1e-10 -0.79 1.00 0.00 FALSE
65 NTR Blood NUSAP1 0.03 0.03 lasso 3 0.04 4.9e-12 -7.3 -6.0 2.6e-09 0.58 0.70 0.30 FALSE
66 YFS Blood MGA 0.01 0.00 blup 454 0.00 7.1e-02 -5.8 -5.1 2.7e-07 0.51 0.11 0.15 FALSE
67 The Cancer Genome Atlas Breast Invasive Carcinoma CHP 0.01 0.01 blup 54 0.01 1.4e-02 -6.7 6.4 1.9e-10 -0.70 0.07 0.24 FALSE
68 The Cancer Genome Atlas Breast Invasive Carcinoma LOC729082 0.02 0.01 blup 44 0.02 2.9e-04 -5.9 8.3 1.4e-16 -0.69 0.02 0.97 FALSE
69 The Cancer Genome Atlas Breast Invasive Carcinoma NDUFAF1 0.04 0.02 lasso 2 0.03 8.9e-08 -6.7 -6.3 2.7e-10 0.42 0.14 0.82 FALSE
70 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CHP 0.06 0.01 blup 54 0.03 4.7e-04 -7.8 10.1 8.3e-24 -0.80 0.01 0.96 TRUE
71 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NDUFAF1 0.14 0.07 enet 8 0.10 2.5e-11 -6.7 -6.2 4.7e-10 0.40 0.18 0.82 FALSE
72 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NUSAP1 0.03 0.01 blup 40 0.02 3.4e-03 -7.8 6.8 1.4e-11 -0.59 0.01 0.93 FALSE
73 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma INO80 0.03 0.02 blup 38 0.03 1.1e-02 -2.2 -5.3 1.1e-07 0.72 0.03 0.45 FALSE
74 The Cancer Genome Atlas Brain Lower Grade Glioma NDUFAF1 0.03 0.04 lasso 3 0.04 3.2e-05 -7.4 7.3 2.1e-13 -0.57 0.01 0.99 FALSE
75 The Cancer Genome Atlas Lung Adenocarcinoma NDUFAF1 0.14 0.17 lasso 5 0.18 9.6e-21 -6.6 -6.7 1.6e-11 0.51 0.28 0.72 FALSE
76 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LOC729082 0.06 0.01 enet 6 0.03 3.3e-04 -6.4 8.3 7.2e-17 -0.85 0.02 0.42 FALSE
77 The Cancer Genome Atlas Pancreatic Adenocarcinoma INO80 0.07 0.04 blup 40 0.06 1.2e-03 -5.2 -7.2 6.1e-13 0.79 0.04 0.54 FALSE
78 The Cancer Genome Atlas Pancreatic Adenocarcinoma NDUFAF1 0.23 0.15 lasso 3 0.13 3.7e-06 -7.4 -7.5 6.0e-14 0.61 0.01 0.99 FALSE
79 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC729082 0.15 0.05 blup 44 0.10 8.6e-05 -7.8 5.3 9.3e-08 -0.39 0.01 0.96 FALSE
80 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NDUFAF1 0.18 0.21 blup 28 0.22 5.4e-09 -6.6 -7.2 4.8e-13 0.54 0.04 0.96 FALSE
81 The Cancer Genome Atlas Prostate Adenocarcinoma CHP 0.21 0.11 lasso 4 0.12 5.1e-13 -5.3 6.7 2.0e-11 -0.65 0.99 0.01 FALSE
82 The Cancer Genome Atlas Prostate Adenocarcinoma LOC729082 0.04 0.07 lasso 1 0.06 5.5e-07 -7.4 7.4 9.7e-14 -0.58 0.01 0.99 FALSE
83 The Cancer Genome Atlas Prostate Adenocarcinoma NDUFAF1 0.13 0.16 enet 8 0.17 2.2e-17 -6.6 -6.4 2.0e-10 0.49 0.26 0.74 FALSE
84 The Cancer Genome Atlas Testicular Germ Cell Tumors EXD1 0.33 0.04 enet 12 0.12 6.1e-05 -8.5 -7.5 5.3e-14 0.81 0.00 0.92 FALSE
85 The Cancer Genome Atlas Thyroid Carcinoma CHP 0.05 0.04 blup 54 0.03 6.0e-04 -7.4 7.0 2.3e-12 -0.60 0.01 0.90 FALSE
86 The Cancer Genome Atlas Thyroid Carcinoma INO80 0.03 0.02 blup 39 0.03 1.0e-03 -2.8 -6.1 9.9e-10 0.75 0.17 0.56 FALSE
87 The Cancer Genome Atlas Thyroid Carcinoma NDUFAF1 0.32 0.38 enet 11 0.39 1.2e-39 -6.6 -7.2 8.5e-13 0.54 0.35 0.65 FALSE
88 The Cancer Genome Atlas Thyroid Carcinoma RTF1 0.04 0.02 lasso 3 0.02 4.0e-03 4.3 5.7 1.1e-08 -0.64 0.02 0.88 FALSE