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chr17:20,018,841-22,010,013

Best TWAS P=1.13e-23 · Best GWAS P=1.33e-41 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Thyroid	KCNJ12	0.36	0.23	lasso	5	0.25	2.9e-19	8.8	10.0	1.1e-23	-0.48	1.00	0.00	TRUE
5	GTEx	Lung	C17orf103	0.08	0.01	enet	11	0.04	6.6e-04	-7.7	-9.6	1.3e-21	0.43	0.16	0.48	TRUE
6	GTEx	Skin Sun Exposed Lower leg	C17orf103	0.11	0.02	enet	15	0.07	1.0e-06	-4.6	-8.7	3.2e-18	0.30	0.38	0.08	TRUE
7	GTEx	Testis	C17orf103	0.15	0.21	enet	4	0.19	7.1e-09	6.8	-7.6	2.5e-14	0.16	0.98	0.00	TRUE
15	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf103	0.08	0.01	blup	44	0.01	3.2e-02	6.9	-6.8	1.1e-11	0.29	0.03	0.54	TRUE
3	GTEx	Esophagus Mucosa	TMEM11	0.20	0.00	lasso	7	0.01	9.3e-02	-4.6	-5.6	2.1e-08	0.10	0.08	0.12	TRUE
2	GTEx	Colon Transverse	DHRS7B	0.10	0.09	lasso	3	0.07	2.3e-04	4.3	5.2	2.6e-07	-0.15	0.23	0.46	TRUE
8	GTEx	Thyroid	DHRS7B	0.17	0.02	enet	22	0.11	1.2e-08	4.3	8.7	4.9e-18	-0.17	0.84	0.02	FALSE
4	GTEx	Esophagus Muscularis	C17orf103	0.16	0.06	lasso	5	0.06	2.1e-04	6.9	-7.2	7.0e-13	0.19	0.31	0.03	FALSE
11	NTR	Blood	C17orf103	0.02	0.02	lasso	2	0.02	1.6e-07	6.5	-7.0	2.0e-12	0.14	0.98	0.00	FALSE
10	METSIM	Adipose	MAP2K3	0.08	0.02	blup	211	0.03	6.0e-05	6.4	-6.5	6.4e-11	0.36	0.19	0.70	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	C17orf103	0.03	0.04	lasso	1	0.04	7.9e-08	6.5	-6.5	1.0e-10	0.12	0.98	0.02	FALSE
14	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C17orf103	0.13	0.14	lasso	1	0.11	2.9e-05	6.5	-6.5	1.0e-10	0.12	0.17	0.16	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf103	0.05	0.04	lasso	3	0.02	5.4e-03	6.5	-6.0	1.8e-09	0.11	0.05	0.18	FALSE
1	GTEx	Colon Sigmoid	ABHD17AP6	0.15	-0.01	lasso	6	-0.01	6.9e-01	-3.9	-5.6	2.7e-08	0.20	0.03	0.10	FALSE