Best TWAS P=1.45e-17 · Best GWAS P=1.5e-15 conditioned to 0.797
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CCDC144B | 0.21 | 0.05 | enet | 30 | 0.16 | 1.5e-18 | 6.72 | 7.1 | 1.1e-12 | 0.63 | 0.08 | 0.92 | FALSE |
2 | CommonMind | Brain Pre-frontal Cortex | FAM106A | 0.05 | 0.01 | bslmm | 278 | 0.02 | 8.6e-04 | 1.38 | 5.8 | 5.4e-09 | 0.48 | 0.08 | 0.30 | FALSE |
3 | CommonMind | Brain Pre-frontal Cortex | MYO15A | 0.17 | 0.12 | bslmm | 313 | 0.14 | 4.5e-16 | 7.77 | -7.0 | 3.5e-12 | -0.77 | 0.01 | 0.99 | FALSE |
4 | CommonMind | Brain Pre-frontal Cortex | SHMT1 | 0.22 | 0.14 | enet | 16 | 0.17 | 5.5e-20 | 6.85 | -7.4 | 1.2e-13 | -0.61 | 0.94 | 0.06 | FALSE |
5 | GTEx | Adipose Subcutaneous | ALKBH5 | 0.19 | 0.18 | lasso | 2 | 0.17 | 1.0e-13 | -6.89 | -6.9 | 6.8e-12 | -0.61 | 0.84 | 0.16 | FALSE |
6 | GTEx | Adipose Subcutaneous | PEMT | 0.17 | 0.13 | enet | 11 | 0.12 | 3.6e-10 | 4.09 | 5.3 | 9.5e-08 | 0.18 | 0.07 | 0.89 | TRUE |
7 | GTEx | Adipose Subcutaneous | SHMT1 | 0.20 | 0.07 | lasso | 9 | 0.04 | 1.4e-04 | 6.77 | -6.4 | 1.3e-10 | -0.59 | 0.51 | 0.38 | FALSE |
8 | GTEx | Adipose Subcutaneous | RP11-258F1.1 | 0.19 | 0.13 | lasso | 4 | 0.12 | 3.6e-10 | -6.89 | -6.9 | 5.4e-12 | -0.64 | 0.82 | 0.18 | FALSE |
9 | GTEx | Adipose Subcutaneous | CTD-2303H24.2 | 0.16 | 0.11 | enet | 15 | 0.18 | 2.4e-14 | -6.75 | 7.4 | 1.3e-13 | 0.63 | 0.50 | 0.50 | FALSE |
10 | GTEx | Adipose Visceral Omentum | TRIM16L | 0.19 | 0.00 | enet | 27 | 0.06 | 7.4e-04 | -0.75 | -5.8 | 6.5e-09 | -0.46 | 0.09 | 0.40 | FALSE |
11 | GTEx | Adipose Visceral Omentum | RP11-258F1.1 | 0.08 | 0.02 | lasso | 2 | 0.03 | 1.3e-02 | -6.80 | -6.8 | 1.1e-11 | -0.61 | 0.18 | 0.22 | FALSE |
12 | GTEx | Adipose Visceral Omentum | CTD-2303H24.2 | 0.35 | 0.10 | enet | 14 | 0.23 | 2.8e-12 | 7.69 | 8.4 | 6.5e-17 | 0.80 | 0.01 | 0.99 | FALSE |
13 | GTEx | Adrenal Gland | SHMT1 | 0.57 | 0.25 | enet | 25 | 0.33 | 9.9e-13 | -3.34 | -5.6 | 1.8e-08 | -0.45 | 0.43 | 0.54 | FALSE |
14 | GTEx | Adrenal Gland | CTD-2303H24.2 | 0.31 | 0.05 | lasso | 7 | 0.12 | 3.6e-05 | 1.48 | 5.9 | 3.5e-09 | 0.67 | 0.07 | 0.76 | FALSE |
15 | GTEx | Artery Aorta | ALKBH5 | 0.08 | 0.05 | lasso | 7 | 0.06 | 5.2e-04 | -4.69 | -6.8 | 9.2e-12 | -0.64 | 0.11 | 0.73 | FALSE |
16 | GTEx | Artery Aorta | SHMT1 | 0.35 | 0.20 | enet | 23 | 0.31 | 1.3e-17 | -4.69 | -7.2 | 8.8e-13 | -0.55 | 0.97 | 0.03 | FALSE |
17 | GTEx | Artery Aorta | TOP3A | 0.13 | 0.11 | enet | 8 | 0.15 | 1.8e-08 | -4.72 | 6.0 | 1.5e-09 | 0.55 | 0.87 | 0.12 | FALSE |
18 | GTEx | Artery Aorta | RP11-258F1.1 | 0.11 | 0.12 | lasso | 5 | 0.10 | 4.7e-06 | -7.00 | -6.9 | 3.8e-12 | -0.62 | 0.51 | 0.42 | FALSE |
19 | GTEx | Artery Aorta | CTD-2303H24.2 | 0.39 | 0.12 | enet | 37 | 0.27 | 3.7e-15 | -6.75 | 6.9 | 6.4e-12 | 0.57 | 0.02 | 0.98 | FALSE |
20 | GTEx | Artery Coronary | CCDC144B | 0.14 | 0.02 | lasso | 5 | 0.02 | 5.2e-02 | 5.52 | -5.3 | 1.1e-07 | -0.44 | 0.08 | 0.20 | FALSE |
21 | GTEx | Artery Coronary | CTD-2303H24.2 | 0.38 | 0.04 | lasso | 7 | 0.20 | 3.8e-07 | 6.66 | 6.5 | 7.9e-11 | 0.58 | 0.06 | 0.86 | FALSE |
22 | GTEx | Artery Tibial | ALKBH5 | 0.17 | 0.16 | lasso | 5 | 0.15 | 4.8e-12 | -7.00 | -7.0 | 2.0e-12 | -0.65 | 0.79 | 0.21 | FALSE |
23 | GTEx | Artery Tibial | SHMT1 | 0.49 | 0.29 | lasso | 6 | 0.44 | 4.0e-38 | -4.69 | -6.7 | 2.4e-11 | -0.52 | 0.96 | 0.04 | FALSE |
24 | GTEx | Artery Tibial | RP11-258F1.1 | 0.18 | 0.15 | lasso | 3 | 0.15 | 1.6e-11 | -6.89 | -6.9 | 5.2e-12 | -0.61 | 0.82 | 0.18 | FALSE |
25 | GTEx | Artery Tibial | CTD-2303H24.2 | 0.32 | 0.17 | lasso | 7 | 0.23 | 7.1e-18 | 6.66 | 7.2 | 4.4e-13 | 0.61 | 0.96 | 0.04 | FALSE |
26 | GTEx | Brain Caudate basal ganglia | ALKBH5 | 0.12 | 0.00 | lasso | 6 | 0.03 | 4.4e-02 | 3.50 | -5.7 | 1.3e-08 | -0.41 | 0.19 | 0.10 | FALSE |
27 | GTEx | Brain Cerebellar Hemisphere | CTD-2303H24.2 | 0.53 | 0.08 | enet | 50 | 0.15 | 1.4e-04 | 6.66 | 5.9 | 3.8e-09 | 0.54 | 0.11 | 0.46 | FALSE |
28 | GTEx | Brain Cerebellum | TOP3A | 0.22 | 0.09 | lasso | 5 | 0.15 | 3.0e-05 | 6.81 | 7.5 | 7.5e-14 | 0.67 | 0.08 | 0.87 | FALSE |
29 | GTEx | Brain Cerebellum | CTD-2303H24.2 | 0.46 | 0.15 | lasso | 5 | 0.12 | 2.8e-04 | 6.66 | 6.0 | 2.1e-09 | 0.49 | 0.11 | 0.25 | FALSE |
30 | GTEx | Brain Cortex | TOP3A | 0.21 | 0.13 | enet | 11 | 0.09 | 1.8e-03 | 7.33 | 7.8 | 4.7e-15 | 0.81 | 0.04 | 0.74 | FALSE |
31 | GTEx | Brain Cortex | CTD-2303H24.2 | 0.34 | 0.08 | enet | 42 | 0.15 | 5.3e-05 | 6.85 | 6.1 | 1.3e-09 | 0.49 | 0.06 | 0.46 | FALSE |
32 | GTEx | Brain Hippocampus | RP11-815I9.4 | 0.18 | 0.05 | lasso | 4 | 0.08 | 7.3e-03 | 7.66 | 7.7 | 1.7e-14 | 0.76 | 0.04 | 0.54 | FALSE |
33 | GTEx | Breast Mammary Tissue | ALKBH5 | 0.07 | 0.09 | enet | 6 | 0.08 | 6.1e-05 | -6.89 | -7.5 | 4.3e-14 | -0.68 | 0.09 | 0.74 | FALSE |
34 | GTEx | Breast Mammary Tissue | CTD-2303H24.2 | 0.32 | 0.07 | enet | 34 | 0.15 | 5.3e-08 | 6.66 | 6.9 | 4.3e-12 | 0.61 | 0.33 | 0.50 | FALSE |
35 | GTEx | Breast Mammary Tissue (Male) | TOP3A | 0.24 | 0.12 | enet | 25 | 0.19 | 2.9e-05 | -4.72 | 6.0 | 1.7e-09 | 0.42 | 0.05 | 0.06 | FALSE |
36 | GTEx | Breast Mammary Tissue (Male) | CTD-2303H24.2 | 0.27 | 0.00 | enet | 33 | 0.01 | 1.5e-01 | 6.66 | 7.1 | 1.0e-12 | 0.62 | 0.04 | 0.23 | FALSE |
37 | GTEx | Breast Mammary Tissue (Female) | ALKBH5 | 0.12 | 0.08 | lasso | 3 | 0.08 | 2.3e-03 | -7.00 | -7.3 | 2.3e-13 | -0.68 | 0.05 | 0.70 | FALSE |
38 | GTEx | Breast Mammary Tissue (Female) | CTD-2303H24.2 | 0.41 | 0.02 | enet | 30 | 0.14 | 7.5e-05 | -6.75 | 6.1 | 1.3e-09 | 0.52 | 0.08 | 0.26 | FALSE |
39 | GTEx | Cells EBV-transformed lymphocytes | SHMT1 | 0.38 | 0.26 | lasso | 10 | 0.24 | 2.7e-08 | 6.67 | -7.7 | 1.2e-14 | -0.69 | 0.33 | 0.66 | FALSE |
40 | GTEx | Cells Transformed fibroblasts | ALKBH5 | 0.16 | 0.05 | lasso | 7 | 0.10 | 9.2e-08 | -7.00 | -5.9 | 2.8e-09 | -0.60 | 0.84 | 0.15 | FALSE |
41 | GTEx | Cells Transformed fibroblasts | SHMT1 | 0.42 | 0.27 | lasso | 7 | 0.39 | 2.7e-31 | -4.69 | -6.7 | 2.3e-11 | -0.56 | 1.00 | 0.00 | FALSE |
42 | GTEx | Cells Transformed fibroblasts | RP11-258F1.1 | 0.18 | 0.12 | lasso | 3 | 0.15 | 1.7e-11 | -7.00 | -6.5 | 1.0e-10 | -0.63 | 0.80 | 0.20 | FALSE |
43 | GTEx | Cells Transformed fibroblasts | CTD-2303H24.2 | 0.29 | 0.10 | lasso | 3 | 0.12 | 5.8e-09 | 6.66 | 7.2 | 8.6e-13 | 0.56 | 0.96 | 0.04 | FALSE |
44 | GTEx | Colon Sigmoid | TOP3A | 0.51 | 0.08 | lasso | 15 | 0.16 | 2.9e-06 | 6.75 | 5.5 | 4.9e-08 | 0.38 | 0.26 | 0.28 | FALSE |
45 | GTEx | Colon Sigmoid | RP11-258F1.1 | 0.09 | 0.01 | lasso | 13 | 0.00 | 2.1e-01 | -6.89 | -5.6 | 2.1e-08 | -0.43 | 0.10 | 0.05 | FALSE |
46 | GTEx | Colon Sigmoid | CTD-2303H24.2 | 0.55 | 0.33 | enet | 37 | 0.30 | 4.2e-11 | -6.75 | 7.1 | 1.1e-12 | 0.54 | 0.91 | 0.08 | FALSE |
47 | GTEx | Colon Transverse | ALKBH5 | 0.16 | 0.08 | lasso | 4 | 0.07 | 3.4e-04 | -6.87 | -6.8 | 1.3e-11 | -0.59 | 0.20 | 0.41 | FALSE |
48 | GTEx | Colon Transverse | TOP3A | 0.11 | 0.04 | lasso | 5 | 0.07 | 3.5e-04 | -7.00 | 7.6 | 3.3e-14 | 0.76 | 0.10 | 0.81 | FALSE |
49 | GTEx | Colon Transverse | CTD-2303H24.2 | 0.08 | 0.08 | lasso | 4 | 0.04 | 5.9e-03 | -6.75 | 7.4 | 1.6e-13 | 0.65 | 0.08 | 0.68 | FALSE |
50 | GTEx | Esophagus Gastroesophageal Junction | SHMT1 | 0.15 | 0.00 | lasso | 4 | 0.00 | 2.5e-01 | 7.81 | -7.6 | 3.2e-14 | -0.85 | 0.02 | 0.77 | FALSE |
51 | GTEx | Esophagus Gastroesophageal Junction | RP11-258F1.1 | 0.34 | 0.12 | lasso | 1 | 0.10 | 1.6e-04 | -6.80 | -6.8 | 1.1e-11 | -0.61 | 0.23 | 0.26 | FALSE |
52 | GTEx | Esophagus Gastroesophageal Junction | CTD-2303H24.2 | 0.33 | 0.20 | lasso | 3 | 0.34 | 6.0e-13 | -6.75 | 8.5 | 1.5e-17 | 0.84 | 0.03 | 0.97 | TRUE |
53 | GTEx | Esophagus Mucosa | ALKBH5 | 0.09 | 0.08 | lasso | 8 | 0.06 | 9.3e-05 | -7.00 | -5.6 | 1.7e-08 | -0.49 | 0.40 | 0.16 | FALSE |
54 | GTEx | Esophagus Mucosa | DRG2 | 0.06 | 0.00 | enet | 19 | 0.01 | 1.3e-01 | 4.29 | -5.2 | 1.5e-07 | -0.37 | 0.12 | 0.05 | FALSE |
55 | GTEx | Esophagus Mucosa | LLGL1 | 0.38 | 0.39 | lasso | 6 | 0.39 | 8.0e-28 | -5.11 | -5.2 | 2.3e-07 | -0.55 | 1.00 | 0.00 | FALSE |
56 | GTEx | Esophagus Mucosa | SHMT1 | 0.25 | 0.03 | enet | 49 | 0.06 | 1.3e-04 | 7.57 | -5.6 | 2.5e-08 | -0.46 | 0.04 | 0.88 | FALSE |
57 | GTEx | Esophagus Mucosa | TOP3A | 0.08 | 0.04 | enet | 10 | 0.05 | 4.1e-04 | 5.52 | 6.6 | 4.3e-11 | 0.52 | 0.12 | 0.72 | FALSE |
58 | GTEx | Esophagus Mucosa | RP11-258F1.1 | 0.12 | 0.11 | lasso | 3 | 0.10 | 2.5e-07 | -7.00 | -7.3 | 2.1e-13 | -0.62 | 0.72 | 0.25 | FALSE |
59 | GTEx | Esophagus Mucosa | CTD-2303H24.2 | 0.21 | 0.09 | enet | 29 | 0.17 | 2.4e-11 | -6.75 | 8.2 | 2.1e-16 | 0.68 | 0.04 | 0.96 | FALSE |
60 | GTEx | Esophagus Muscularis | ALKBH5 | 0.12 | 0.16 | lasso | 2 | 0.14 | 7.3e-09 | -7.00 | -7.0 | 3.8e-12 | -0.62 | 0.82 | 0.18 | FALSE |
61 | GTEx | Esophagus Muscularis | LLGL1 | 0.19 | 0.06 | lasso | 5 | 0.06 | 1.1e-04 | 7.67 | 7.9 | 3.6e-15 | 0.96 | 0.02 | 0.98 | FALSE |
62 | GTEx | Esophagus Muscularis | SHMT1 | 0.28 | 0.21 | lasso | 5 | 0.34 | 2.3e-21 | 6.85 | -6.9 | 6.8e-12 | -0.54 | 0.90 | 0.10 | FALSE |
63 | GTEx | Esophagus Muscularis | RP11-258F1.1 | 0.19 | 0.17 | lasso | 6 | 0.13 | 3.1e-08 | -7.00 | -6.9 | 3.9e-12 | -0.63 | 0.83 | 0.17 | FALSE |
64 | GTEx | Esophagus Muscularis | CTD-2303H24.2 | 0.25 | 0.09 | lasso | 5 | 0.16 | 8.4e-10 | -6.75 | 8.3 | 1.1e-16 | 0.79 | 0.04 | 0.96 | FALSE |
65 | GTEx | Heart Atrial Appendage | TOM1L2 | 0.12 | 0.04 | enet | 2 | 0.04 | 7.0e-03 | 7.05 | -7.1 | 1.5e-12 | -0.76 | 0.05 | 0.83 | FALSE |
66 | GTEx | Heart Atrial Appendage | SHMT1 | 0.12 | 0.06 | lasso | 4 | 0.06 | 1.1e-03 | 6.72 | -7.2 | 4.9e-13 | -0.59 | 0.16 | 0.43 | FALSE |
67 | GTEx | Heart Atrial Appendage | AC122129.1 | 0.15 | 0.02 | enet | 9 | 0.08 | 1.4e-04 | 7.43 | -6.0 | 2.3e-09 | -0.64 | 0.06 | 0.80 | FALSE |
68 | GTEx | Heart Atrial Appendage | CTD-2303H24.2 | 0.26 | 0.11 | lasso | 6 | 0.13 | 1.5e-06 | -6.75 | 7.0 | 1.7e-12 | 0.67 | 0.02 | 0.96 | FALSE |
69 | GTEx | Heart Left Ventricle | RP11-258F1.1 | 0.09 | 0.06 | lasso | 2 | 0.04 | 2.4e-03 | -6.80 | -6.7 | 1.6e-11 | -0.61 | 0.17 | 0.54 | FALSE |
70 | GTEx | Heart Left Ventricle | CTD-2303H24.2 | 0.24 | 0.04 | lasso | 6 | 0.10 | 4.3e-06 | 7.69 | 8.4 | 6.5e-17 | 0.83 | 0.01 | 0.98 | FALSE |
71 | GTEx | Lung | SHMT1 | 0.15 | 0.13 | lasso | 6 | 0.16 | 2.4e-12 | -3.34 | -6.2 | 5.9e-10 | -0.49 | 0.94 | 0.06 | FALSE |
72 | GTEx | Lung | CTD-2303H24.2 | 0.45 | 0.12 | lasso | 6 | 0.27 | 1.3e-20 | 6.66 | 7.2 | 6.6e-13 | 0.58 | 0.90 | 0.10 | FALSE |
73 | GTEx | Muscle Skeletal | ALKBH5 | 0.10 | 0.09 | lasso | 3 | 0.07 | 2.0e-07 | -6.89 | -6.7 | 2.1e-11 | -0.61 | 0.86 | 0.14 | FALSE |
74 | GTEx | Muscle Skeletal | SHMT1 | 0.16 | 0.08 | lasso | 5 | 0.13 | 1.0e-12 | 6.85 | -7.0 | 2.3e-12 | -0.58 | 0.87 | 0.13 | FALSE |
75 | GTEx | Muscle Skeletal | RP11-258F1.1 | 0.09 | 0.10 | lasso | 2 | 0.09 | 2.2e-09 | -6.80 | -6.8 | 7.5e-12 | -0.61 | 0.86 | 0.14 | FALSE |
76 | GTEx | Muscle Skeletal | CTD-2303H24.2 | 0.23 | 0.11 | enet | 23 | 0.17 | 5.2e-16 | -6.75 | 6.7 | 1.7e-11 | 0.57 | 0.32 | 0.68 | FALSE |
77 | GTEx | Nerve Tibial | ALKBH5 | 0.27 | 0.19 | lasso | 3 | 0.16 | 1.1e-11 | -6.80 | -6.9 | 6.9e-12 | -0.61 | 0.85 | 0.15 | FALSE |
78 | GTEx | Nerve Tibial | SHMT1 | 0.30 | 0.20 | lasso | 6 | 0.29 | 5.5e-21 | -4.69 | -7.1 | 1.2e-12 | -0.60 | 0.98 | 0.02 | FALSE |
79 | GTEx | Nerve Tibial | TOP3A | 0.35 | 0.21 | lasso | 12 | 0.18 | 1.1e-12 | 6.67 | 6.5 | 1.1e-10 | 0.56 | 0.96 | 0.04 | FALSE |
80 | GTEx | Nerve Tibial | RP11-258F1.1 | 0.16 | 0.15 | lasso | 1 | 0.15 | 7.5e-11 | -6.89 | -6.9 | 5.5e-12 | -0.62 | 0.79 | 0.21 | FALSE |
81 | GTEx | Nerve Tibial | CTD-2303H24.2 | 0.23 | 0.08 | enet | 15 | 0.18 | 9.4e-13 | -6.75 | 7.3 | 3.2e-13 | 0.62 | 0.27 | 0.73 | FALSE |
82 | GTEx | Pituitary | CTD-2303H24.2 | 0.27 | 0.04 | lasso | 8 | 0.08 | 4.1e-03 | 6.66 | 7.0 | 1.9e-12 | 0.67 | 0.04 | 0.40 | FALSE |
83 | GTEx | Skin Not Sun Exposed Suprapubic | CTD-2303H24.2 | 0.27 | 0.08 | lasso | 5 | 0.17 | 1.6e-09 | 6.66 | 8.3 | 1.1e-16 | 0.80 | 0.07 | 0.93 | FALSE |
84 | GTEx | Skin Sun Exposed Lower leg | ALKBH5 | 0.16 | 0.14 | lasso | 3 | 0.13 | 1.0e-10 | -6.89 | -6.9 | 4.6e-12 | -0.62 | 0.83 | 0.17 | FALSE |
85 | GTEx | Skin Sun Exposed Lower leg | RP11-258F1.1 | 0.12 | 0.10 | lasso | 5 | 0.09 | 9.9e-08 | -6.89 | -6.9 | 4.4e-12 | -0.61 | 0.75 | 0.25 | FALSE |
86 | GTEx | Skin Sun Exposed Lower leg | CTD-2303H24.2 | 0.24 | 0.08 | enet | 20 | 0.13 | 3.9e-11 | 6.66 | 6.9 | 4.7e-12 | 0.61 | 0.79 | 0.21 | FALSE |
87 | GTEx | Small Intestine Terminal Ileum | TOP3A | 0.25 | 0.09 | lasso | 5 | 0.06 | 1.8e-02 | 7.66 | 7.2 | 8.8e-13 | 0.65 | 0.06 | 0.46 | FALSE |
88 | GTEx | Small Intestine Terminal Ileum | CTD-2303H24.2 | 0.38 | 0.28 | lasso | 9 | 0.26 | 1.7e-06 | 7.98 | 8.2 | 3.0e-16 | 0.99 | 0.01 | 0.98 | FALSE |
89 | GTEx | Spleen | TOP3A | 0.33 | 0.16 | lasso | 6 | 0.21 | 5.1e-06 | -4.51 | 5.6 | 1.7e-08 | 0.53 | 0.43 | 0.18 | FALSE |
90 | GTEx | Spleen | CTD-2303H24.2 | 0.32 | 0.02 | enet | 15 | 0.12 | 5.2e-04 | 7.69 | 7.5 | 5.6e-14 | 0.78 | 0.03 | 0.81 | FALSE |
91 | GTEx | Stomach | SHMT1 | 0.21 | 0.05 | enet | 18 | 0.08 | 1.4e-04 | -4.69 | -6.6 | 3.4e-11 | -0.51 | 0.55 | 0.34 | FALSE |
92 | GTEx | Stomach | RP11-258F1.1 | 0.13 | 0.12 | lasso | 1 | 0.10 | 2.4e-05 | -6.80 | -6.8 | 1.1e-11 | -0.61 | 0.60 | 0.33 | FALSE |
93 | GTEx | Testis | SHMT1 | 0.28 | 0.05 | enet | 20 | 0.12 | 7.6e-06 | -3.31 | 5.7 | 1.3e-08 | 0.43 | 0.12 | 0.11 | FALSE |
94 | GTEx | Testis | RP11-258F1.1 | 0.17 | 0.10 | lasso | 3 | 0.10 | 2.9e-05 | -6.89 | -7.9 | 2.8e-15 | -0.79 | 0.03 | 0.95 | FALSE |
95 | GTEx | Testis | CTD-2303H24.2 | 0.50 | 0.26 | lasso | 17 | 0.36 | 1.1e-16 | -6.75 | 7.0 | 2.9e-12 | 0.60 | 0.51 | 0.49 | FALSE |
96 | GTEx | Thyroid | TOP3A | 0.14 | 0.08 | lasso | 3 | 0.09 | 1.5e-07 | -3.34 | 5.8 | 7.5e-09 | 0.53 | 0.18 | 0.82 | FALSE |
97 | GTEx | Thyroid | CTD-2303H24.2 | 0.20 | 0.14 | enet | 8 | 0.13 | 1.9e-10 | 6.66 | 7.9 | 2.8e-15 | 0.67 | 0.66 | 0.34 | FALSE |
98 | GTEx | Vagina | SHMT1 | 0.38 | 0.02 | lasso | 4 | -0.01 | 6.6e-01 | 7.69 | 6.8 | 7.6e-12 | 0.90 | 0.01 | 0.75 | FALSE |
99 | GTEx | Whole Blood | CCDC144B | 0.05 | 0.06 | lasso | 2 | 0.06 | 3.2e-06 | -4.68 | -6.0 | 1.5e-09 | -0.47 | 0.36 | 0.21 | FALSE |
100 | GTEx | Whole Blood | CTD-2303H24.2 | 0.04 | 0.02 | lasso | 4 | 0.04 | 8.4e-05 | 7.69 | 8.4 | 5.3e-17 | 0.89 | 0.01 | 0.96 | FALSE |
101 | METSIM | Adipose | FAM106A | 0.20 | 0.13 | enet | 21 | 0.15 | 5.8e-22 | 6.85 | 7.0 | 2.4e-12 | 0.56 | 0.94 | 0.06 | FALSE |
102 | METSIM | Adipose | LGALS9C | 0.07 | 0.06 | lasso | 6 | 0.05 | 6.5e-08 | 6.66 | 7.8 | 7.1e-15 | 0.70 | 0.36 | 0.64 | FALSE |
103 | METSIM | Adipose | PEMT | 0.13 | 0.09 | lasso | 8 | 0.11 | 2.6e-16 | 3.78 | 5.2 | 1.6e-07 | 0.20 | 0.22 | 0.65 | FALSE |
104 | METSIM | Adipose | SHMT1 | 0.12 | 0.02 | bslmm | 259 | 0.03 | 5.4e-05 | 6.66 | -7.1 | 1.2e-12 | -0.44 | 0.45 | 0.41 | FALSE |
105 | ROSMAP | Brain Pre-frontal Cortex | TOP3A | 0.15 | 0.09 | lasso | 7 | 0.14 | 2.8e-17 | 7.72 | 7.1 | 1.3e-12 | 0.64 | 0.05 | 0.95 | FALSE |
106 | ROSMAP | Brain Pre-frontal Cortex | USP32P2 | 0.74 | 0.61 | enet | 18 | 0.65 | 4.4e-110 | -6.75 | 7.3 | 2.9e-13 | 0.57 | 0.95 | 0.05 | FALSE |
107 | YFS | Blood | SHMT1 | 0.46 | 0.28 | bslmm | 255 | 0.41 | 7.3e-145 | 6.67 | -6.2 | 4.8e-10 | -0.47 | 0.95 | 0.05 | FALSE |
108 | YFS | Blood | TOP3A | 0.04 | 0.02 | enet | 20 | 0.03 | 9.3e-10 | 7.69 | 6.2 | 6.0e-10 | 0.77 | 0.01 | 0.99 | FALSE |
109 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ALKBH5 | 0.05 | 0.02 | lasso | 2 | 0.03 | 3.1e-03 | -6.88 | -8.2 | 1.6e-16 | -0.89 | 0.01 | 0.79 | FALSE |
110 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | FLII | 0.04 | 0.02 | blup | 48 | 0.03 | 2.2e-03 | 7.98 | -8.1 | 4.1e-16 | -0.94 | 0.00 | 0.88 | FALSE |
111 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | LLGL1 | 0.07 | 0.04 | blup | 53 | 0.03 | 6.6e-04 | -4.72 | -7.3 | 2.9e-13 | -0.80 | 0.04 | 0.68 | FALSE |
112 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SHMT1 | 0.06 | 0.07 | lasso | 2 | 0.06 | 8.3e-06 | 6.75 | -6.8 | 1.3e-11 | -0.62 | 0.01 | 0.99 | FALSE |
113 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | TOP3A | 0.05 | 0.01 | blup | 53 | 0.02 | 1.0e-02 | -3.18 | -6.2 | 4.3e-10 | -0.67 | 0.06 | 0.20 | FALSE |
114 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ALKBH5 | 0.06 | 0.02 | blup | 63 | 0.02 | 7.2e-06 | 2.14 | -6.7 | 2.8e-11 | -0.61 | 0.05 | 0.80 | FALSE |
115 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FLII | 0.04 | 0.01 | blup | 47 | 0.02 | 7.2e-05 | 7.64 | -6.8 | 1.2e-11 | -0.77 | 0.01 | 0.89 | FALSE |
116 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LLGL1 | 0.09 | 0.01 | blup | 52 | 0.02 | 1.1e-05 | -4.72 | -8.4 | 4.8e-17 | -0.75 | 0.04 | 0.93 | FALSE |
117 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SHMT1 | 0.06 | 0.05 | blup | 33 | 0.05 | 8.2e-11 | 6.66 | -7.4 | 1.7e-13 | -0.61 | 0.01 | 0.99 | FALSE |
118 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMCR7 | 0.06 | 0.00 | enet | 7 | 0.02 | 1.5e-05 | 1.38 | -5.7 | 1.1e-08 | -0.60 | 0.02 | 0.66 | FALSE |
119 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMCR8 | 0.02 | 0.01 | blup | 34 | 0.01 | 1.5e-02 | 1.38 | -6.0 | 2.7e-09 | -0.61 | 0.01 | 0.05 | FALSE |
120 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TOP3A | 0.05 | 0.02 | enet | 8 | 0.03 | 1.2e-07 | -3.62 | -6.7 | 1.8e-11 | -0.70 | 0.02 | 0.98 | FALSE |
121 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ALKBH5 | 0.07 | 0.05 | blup | 63 | 0.05 | 2.1e-03 | -5.10 | -6.6 | 4.9e-11 | -0.58 | 0.04 | 0.29 | FALSE |
122 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SHMT1 | 0.11 | 0.05 | lasso | 3 | 0.04 | 4.0e-03 | -4.69 | -6.2 | 4.3e-10 | -0.53 | 0.01 | 0.64 | FALSE |
123 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SMCR7 | 0.19 | 0.03 | blup | 33 | 0.06 | 4.5e-04 | 1.38 | -6.4 | 1.4e-10 | -0.71 | 0.01 | 0.75 | FALSE |
124 | The Cancer Genome Atlas | Colon Adenocarcinoma | ALKBH5 | 0.14 | 0.07 | lasso | 4 | 0.09 | 5.5e-06 | -6.88 | -7.7 | 1.7e-14 | -0.76 | 0.26 | 0.74 | FALSE |
125 | The Cancer Genome Atlas | Colon Adenocarcinoma | LLGL1 | 0.14 | 0.13 | enet | 8 | 0.14 | 3.2e-08 | -5.10 | -6.5 | 6.4e-11 | -0.70 | 0.86 | 0.11 | FALSE |
126 | The Cancer Genome Atlas | Colon Adenocarcinoma | SHMT1 | 0.08 | 0.06 | enet | 9 | 0.06 | 1.6e-04 | -4.69 | -5.3 | 1.4e-07 | -0.44 | 0.56 | 0.25 | FALSE |
127 | The Cancer Genome Atlas | Colon Adenocarcinoma | SMCR8 | 0.09 | 0.00 | enet | 13 | 0.04 | 2.3e-03 | -4.51 | -5.5 | 4.3e-08 | -0.50 | 0.01 | 0.36 | FALSE |
128 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ALKBH5 | 0.02 | 0.02 | enet | 4 | 0.02 | 3.9e-03 | -6.87 | -6.9 | 6.6e-12 | -0.61 | 0.05 | 0.31 | FALSE |
129 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | LLGL1 | 0.08 | 0.03 | blup | 52 | 0.05 | 1.9e-06 | -5.11 | -7.9 | 2.3e-15 | -0.77 | 0.05 | 0.95 | FALSE |
130 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SHMT1 | 0.12 | 0.06 | blup | 32 | 0.07 | 1.6e-08 | 6.77 | -7.6 | 2.7e-14 | -0.67 | 0.00 | 1.00 | FALSE |
131 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SMCR7 | 0.07 | 0.02 | lasso | 3 | 0.01 | 8.3e-03 | -4.96 | -7.1 | 1.1e-12 | -0.82 | 0.01 | 0.78 | FALSE |
132 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SMCR8 | 0.10 | 0.02 | blup | 33 | 0.03 | 8.1e-05 | -4.95 | -6.7 | 1.9e-11 | -0.67 | 0.03 | 0.46 | FALSE |
133 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | TOP3A | 0.07 | 0.02 | blup | 48 | 0.02 | 1.3e-03 | 7.64 | -7.2 | 5.4e-13 | -0.83 | 0.00 | 0.97 | FALSE |
134 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ALKBH5 | 0.05 | 0.05 | lasso | 3 | 0.04 | 1.7e-05 | -6.79 | -6.7 | 2.8e-11 | -0.60 | 0.66 | 0.19 | FALSE |
135 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | EVPLL | 0.04 | 0.00 | blup | 22 | 0.00 | 2.8e-01 | 6.85 | 5.2 | 1.7e-07 | 0.53 | 0.00 | 0.64 | FALSE |
136 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SMCR7 | 0.04 | 0.01 | blup | 34 | 0.02 | 1.0e-03 | -3.46 | -6.2 | 6.1e-10 | -0.69 | 0.06 | 0.39 | FALSE |
137 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | FLII | 0.16 | 0.00 | enet | 6 | 0.06 | 1.4e-04 | 1.46 | -6.0 | 2.5e-09 | -0.64 | 0.02 | 0.41 | FALSE |
138 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | TOP3A | 0.11 | 0.01 | enet | 10 | 0.05 | 5.8e-04 | 7.64 | -5.3 | 8.7e-08 | -0.70 | 0.01 | 0.76 | FALSE |
139 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MYO15A | 0.04 | 0.02 | lasso | 3 | 0.02 | 2.5e-03 | 7.67 | -7.6 | 3.2e-14 | -0.92 | 0.02 | 0.81 | FALSE |
140 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | SHMT1 | 0.20 | 0.18 | lasso | 5 | 0.16 | 3.2e-08 | 6.77 | -6.7 | 2.9e-11 | -0.60 | 0.00 | 1.00 | FALSE |
141 | The Cancer Genome Atlas | Lung Adenocarcinoma | ALKBH5 | 0.09 | 0.02 | lasso | 3 | 0.03 | 1.2e-04 | 7.64 | -6.6 | 4.6e-11 | -0.84 | 0.01 | 0.96 | FALSE |
142 | The Cancer Genome Atlas | Lung Adenocarcinoma | FLII | 0.04 | 0.01 | blup | 47 | 0.03 | 5.1e-04 | 7.64 | -7.4 | 1.1e-13 | -0.86 | 0.01 | 0.93 | FALSE |
143 | The Cancer Genome Atlas | Lung Adenocarcinoma | LLGL1 | 0.05 | 0.02 | enet | 6 | 0.03 | 7.1e-05 | -5.10 | -7.2 | 5.7e-13 | -0.83 | 0.03 | 0.88 | FALSE |
144 | The Cancer Genome Atlas | Lung Adenocarcinoma | SHMT1 | 0.04 | 0.05 | lasso | 3 | 0.04 | 9.2e-06 | 6.72 | -7.0 | 2.4e-12 | -0.55 | 0.01 | 0.99 | FALSE |
145 | The Cancer Genome Atlas | Lung Adenocarcinoma | SMCR7 | 0.05 | 0.03 | enet | 7 | 0.05 | 3.7e-06 | 7.69 | -6.3 | 2.8e-10 | -0.77 | 0.01 | 0.98 | FALSE |
146 | The Cancer Genome Atlas | Lung Adenocarcinoma | SMCR8 | 0.06 | 0.01 | enet | 9 | 0.03 | 3.3e-04 | -3.65 | -7.1 | 1.3e-12 | -0.68 | 0.01 | 0.72 | FALSE |
147 | The Cancer Genome Atlas | Lung Adenocarcinoma | TOP3A | 0.08 | 0.04 | enet | 8 | 0.07 | 3.7e-08 | -3.18 | -5.4 | 5.3e-08 | -0.68 | 0.11 | 0.89 | FALSE |
148 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ALKBH5 | 0.02 | 0.02 | blup | 63 | 0.01 | 3.4e-02 | -6.88 | -7.0 | 1.7e-12 | -0.67 | 0.08 | 0.38 | FALSE |
149 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | FLII | 0.03 | 0.01 | lasso | 4 | 0.00 | 8.4e-02 | 7.49 | -8.1 | 4.8e-16 | -0.91 | 0.01 | 0.43 | FALSE |
150 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LLGL1 | 0.09 | 0.02 | blup | 52 | 0.04 | 4.9e-05 | -3.34 | -6.1 | 1.2e-09 | -0.60 | 0.22 | 0.68 | FALSE |
151 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | MYO15A | 0.03 | 0.02 | blup | 79 | 0.02 | 9.4e-04 | 7.39 | -6.3 | 2.5e-10 | -0.82 | 0.02 | 0.72 | FALSE |
152 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SHMT1 | 0.07 | 0.03 | enet | 6 | 0.05 | 2.5e-06 | 6.85 | -7.0 | 3.2e-12 | -0.56 | 0.00 | 1.00 | FALSE |
153 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SMCR8 | 0.04 | 0.00 | blup | 33 | 0.00 | 2.0e-01 | 6.81 | -7.4 | 1.8e-13 | -0.72 | 0.00 | 0.42 | FALSE |
154 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TOP3A | 0.08 | 0.00 | blup | 48 | 0.01 | 1.6e-02 | -3.57 | -5.9 | 3.9e-09 | -0.53 | 0.02 | 0.11 | FALSE |
155 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SHMT1 | 0.12 | 0.08 | enet | 5 | 0.07 | 8.8e-04 | 6.77 | -6.8 | 1.3e-11 | -0.58 | 0.01 | 0.82 | FALSE |
156 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ALKBH5 | 0.22 | 0.10 | blup | 66 | 0.12 | 1.4e-05 | 7.67 | -6.8 | 7.5e-12 | -0.72 | 0.02 | 0.87 | FALSE |
157 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | FLII | 0.20 | 0.08 | blup | 54 | 0.13 | 7.0e-06 | 6.75 | -6.1 | 1.1e-09 | -0.74 | 0.04 | 0.65 | FALSE |
158 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SHMT1 | 0.19 | 0.13 | blup | 40 | 0.11 | 3.1e-05 | 6.81 | -7.3 | 3.2e-13 | -0.71 | 0.00 | 0.98 | FALSE |
159 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SMCR7 | 0.13 | 0.05 | enet | 11 | 0.08 | 4.3e-04 | -3.65 | -7.0 | 2.6e-12 | -0.67 | 0.02 | 0.67 | FALSE |
160 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SMCR8 | 0.12 | 0.00 | blup | 43 | 0.06 | 2.0e-03 | 6.75 | -6.0 | 2.1e-09 | -0.57 | 0.00 | 0.28 | FALSE |
161 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ALKBH5 | 0.19 | 0.02 | blup | 63 | 0.04 | 3.4e-05 | 7.98 | -7.0 | 3.8e-12 | -0.78 | 0.01 | 0.98 | FALSE |
162 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FLII | 0.08 | 0.02 | enet | 6 | 0.04 | 1.9e-05 | -3.57 | -7.0 | 2.5e-12 | -0.71 | 0.04 | 0.69 | FALSE |
163 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LLGL1 | 0.10 | 0.04 | lasso | 7 | 0.04 | 7.5e-05 | -4.96 | -6.3 | 2.3e-10 | -0.63 | 0.24 | 0.66 | FALSE |
164 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SMCR7 | 0.07 | 0.04 | blup | 33 | 0.03 | 3.0e-04 | 7.64 | -7.8 | 4.7e-15 | -0.86 | 0.01 | 0.96 | FALSE |
165 | The Cancer Genome Atlas | Rectum Adenocarcinoma | SHMT1 | 0.49 | 0.16 | lasso | 5 | 0.11 | 1.9e-03 | 6.85 | -6.5 | 8.9e-11 | -0.44 | 0.00 | 0.71 | FALSE |
166 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SHMT1 | 0.07 | 0.06 | lasso | 5 | 0.05 | 5.5e-04 | 6.75 | -6.8 | 7.4e-12 | -0.63 | 0.01 | 0.95 | FALSE |
167 | The Cancer Genome Atlas | Soft Tissue Sarcoma | TOP3A | 0.08 | 0.03 | enet | 24 | 0.04 | 1.6e-03 | -3.62 | -5.2 | 2.6e-07 | -0.70 | 0.02 | 0.79 | FALSE |
168 | The Cancer Genome Atlas | Stomach Adenocarcinoma | ALKBH5 | 0.07 | 0.05 | blup | 63 | 0.06 | 2.0e-05 | -6.89 | -7.5 | 6.3e-14 | -0.78 | 0.08 | 0.87 | FALSE |
169 | The Cancer Genome Atlas | Stomach Adenocarcinoma | FLII | 0.05 | 0.04 | blup | 47 | 0.03 | 1.7e-03 | 7.64 | -8.4 | 5.3e-17 | -0.94 | 0.01 | 0.89 | FALSE |
170 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LLGL1 | 0.09 | 0.06 | enet | 6 | 0.05 | 2.5e-04 | -4.72 | -6.1 | 1.1e-09 | -0.57 | 0.18 | 0.36 | FALSE |
171 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SHMT1 | 0.17 | 0.10 | lasso | 2 | 0.08 | 1.0e-06 | 6.75 | -6.9 | 6.2e-12 | -0.63 | 0.01 | 0.99 | FALSE |
172 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SMCR7 | 0.06 | 0.02 | enet | 7 | 0.04 | 9.1e-04 | -4.51 | -5.9 | 3.9e-09 | -0.67 | 0.01 | 0.65 | FALSE |
173 | The Cancer Genome Atlas | Stomach Adenocarcinoma | TOP3A | 0.09 | 0.06 | blup | 48 | 0.05 | 1.8e-04 | -3.57 | -5.3 | 1.1e-07 | -0.62 | 0.31 | 0.44 | FALSE |
174 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ALKBH5 | 0.11 | 0.03 | blup | 64 | 0.04 | 1.8e-02 | -5.10 | -7.9 | 2.0e-15 | -0.82 | 0.02 | 0.52 | FALSE |
175 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | MYO15A | 0.21 | 0.01 | blup | 78 | 0.01 | 1.1e-01 | 7.98 | -5.4 | 7.6e-08 | -0.68 | 0.01 | 0.57 | FALSE |
176 | The Cancer Genome Atlas | Thyroid Carcinoma | ALKBH5 | 0.09 | 0.06 | lasso | 2 | 0.06 | 2.9e-06 | -6.87 | -6.4 | 1.4e-10 | -0.55 | 0.83 | 0.11 | FALSE |
177 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | SMCR8 | 0.60 | 0.03 | blup | 43 | 0.02 | 9.3e-02 | 1.46 | -6.4 | 2.0e-10 | -0.57 | 0.01 | 0.10 | FALSE |