[Hub]/) : Traits : Standing height :

chr20:46,551,079-50,188,292

Best TWAS P=3.6e-43 · Best GWAS P=3.4e-42 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFGEF2 0.09 0.05 lasso 8 0.10 9.2e-13 13.3 -13.0 8.1e-39 -0.82 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex CSE1L 0.08 0.07 bslmm 503 0.05 1.7e-06 -4.7 -8.6 1.0e-17 -0.58 0.92 0.08 FALSE
3 CommonMind Brain Pre-frontal Cortex STAU1 0.09 0.00 bslmm 500 0.01 8.7e-03 -3.6 -5.3 1.0e-07 -0.30 0.26 0.06 TRUE
4 GTEx Artery Tibial CSE1L 0.12 0.03 lasso 6 0.04 3.8e-04 -4.5 -8.2 1.8e-16 -0.68 0.32 0.66 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia BCAS4 0.33 0.01 lasso 7 0.00 4.6e-01 5.8 -6.4 1.2e-10 -0.01 0.06 0.12 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia SLC9A8 0.42 0.09 lasso 7 0.08 3.8e-03 -5.9 5.3 1.2e-07 -0.06 0.07 0.11 FALSE
7 GTEx Cells Transformed fibroblasts STAU1 0.08 0.03 lasso 6 0.02 2.3e-02 10.9 12.1 9.3e-34 0.85 0.03 0.91 FALSE
8 GTEx Cells Transformed fibroblasts ZFAS1 0.06 0.05 enet 5 0.03 2.6e-03 -7.2 7.2 6.6e-13 0.29 0.40 0.28 FALSE
9 GTEx Colon Sigmoid ARFGEF2 0.15 0.12 lasso 1 0.07 2.3e-03 9.4 -9.4 7.5e-21 -0.60 0.06 0.60 FALSE
10 GTEx Colon Sigmoid CSE1L 0.18 0.12 lasso 11 0.09 4.4e-04 11.7 -11.9 1.3e-32 -0.80 0.10 0.86 FALSE
11 GTEx Colon Transverse ARFGEF2 0.11 0.07 enet 12 0.09 2.9e-05 -4.5 -9.7 2.6e-22 -0.78 0.18 0.74 FALSE
12 GTEx Colon Transverse CSE1L 0.17 0.01 enet 19 0.03 1.2e-02 5.0 -7.3 2.7e-13 -0.49 0.18 0.22 FALSE
13 GTEx Esophagus Gastroesophageal Junction CSE1L 0.17 0.07 lasso 5 0.07 1.6e-03 -4.4 -6.5 9.5e-11 -0.49 0.29 0.27 TRUE
14 GTEx Esophagus Mucosa CSE1L 0.09 0.06 lasso 4 0.06 6.9e-05 12.0 -11.1 8.1e-29 -0.80 0.18 0.77 FALSE
15 GTEx Esophagus Mucosa ZFAS1 0.15 0.01 enet 16 0.01 8.9e-02 13.3 8.9 5.4e-19 0.69 0.03 0.90 FALSE
16 GTEx Esophagus Muscularis CSE1L 0.16 0.14 enet 22 0.12 5.1e-08 -4.5 -5.4 6.5e-08 -0.44 0.97 0.03 FALSE
17 GTEx Lung CSE1L 0.10 0.09 lasso 5 0.08 6.6e-07 10.9 -10.8 2.3e-27 -0.73 0.65 0.34 FALSE
18 GTEx Muscle Skeletal PREX1 0.14 0.09 enet 23 0.13 2.5e-12 10.3 8.2 1.6e-16 0.51 0.85 0.15 FALSE
19 GTEx Nerve Tibial CSE1L 0.12 0.01 lasso 10 0.03 5.7e-03 -4.6 -5.4 5.2e-08 -0.48 0.20 0.21 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic ZFAS1 0.16 0.04 enet 19 0.07 1.0e-04 8.6 8.5 1.8e-17 0.69 0.05 0.89 FALSE
21 GTEx Skin Sun Exposed Lower leg CSE1L 0.08 0.03 lasso 2 0.03 9.5e-04 12.2 -11.6 3.0e-31 -0.81 0.47 0.16 FALSE
22 GTEx Skin Sun Exposed Lower leg ZFAS1 0.07 0.03 enet 14 0.05 5.8e-05 13.3 10.1 6.6e-24 0.77 0.03 0.96 FALSE
23 GTEx Testis ARFGEF2 0.20 0.20 lasso 7 0.24 5.4e-11 10.9 -12.8 2.3e-37 -0.91 0.02 0.98 FALSE
24 GTEx Whole Blood ZFAS1 0.07 0.06 lasso 4 0.05 1.3e-05 -7.2 -7.3 2.5e-13 -0.20 1.00 0.00 TRUE
25 METSIM Adipose ARFGEF2 0.04 0.03 lasso 12 0.02 9.8e-05 13.6 -13.8 3.6e-43 -0.98 0.02 0.98 TRUE
26 METSIM Adipose CSE1L 0.05 0.05 lasso 4 0.04 5.3e-07 -4.5 -6.7 2.9e-11 -0.58 0.91 0.09 FALSE
27 METSIM Adipose RP11-290F20.3 0.04 0.03 enet 13 0.02 1.1e-04 4.4 5.2 2.0e-07 0.05 0.66 0.18 TRUE
28 NTR Blood NCRNA00275 0.07 0.06 lasso 4 0.08 9.7e-25 -5.9 -10.5 5.6e-26 -0.53 1.00 0.00 TRUE
29 NTR Blood SNORD12B 0.03 0.05 lasso 8 0.05 1.9e-14 13.3 -13.7 1.2e-42 -0.96 0.02 0.98 FALSE
30 ROSMAP Brain Pre-frontal Cortex CSE1L 0.04 0.02 enet 16 0.02 2.8e-03 9.4 -10.5 7.5e-26 -0.72 0.10 0.89 FALSE
31 YFS Blood CSE1L 0.06 0.05 enet 21 0.06 2.0e-19 -4.6 -9.0 2.2e-19 -0.60 1.00 0.00 FALSE
32 YFS Blood PTPN1 0.37 0.30 enet 21 0.30 1.1e-101 5.8 -6.8 1.2e-11 0.00 0.99 0.01 TRUE
33 YFS Blood ZNFX1 0.06 0.05 lasso 3 0.05 1.4e-16 5.4 -7.1 1.0e-12 -0.55 1.00 0.00 FALSE
34 The Cancer Genome Atlas Breast Invasive Carcinoma STAU1 0.01 0.01 blup 54 0.01 6.1e-03 -7.2 -8.5 2.4e-17 -0.46 0.03 0.13 FALSE
35 The Cancer Genome Atlas Colon Adenocarcinoma SNAI1 0.09 0.10 lasso 5 0.06 3.1e-04 -7.6 7.6 2.2e-14 -0.03 0.20 0.56 TRUE
36 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CSE1L 0.03 0.05 lasso 1 0.03 9.3e-05 10.9 -10.9 1.3e-27 -0.75 0.28 0.64 FALSE
37 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CSE1L 0.05 0.07 blup 50 0.07 3.2e-08 11.6 -11.4 7.0e-30 -0.80 0.42 0.58 FALSE
38 The Cancer Genome Atlas Brain Lower Grade Glioma ARFGEF2 0.05 0.04 lasso 5 0.05 3.2e-06 13.3 -13.6 4.4e-42 -0.94 0.00 1.00 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma SLC9A8 0.07 0.02 blup 82 0.02 8.6e-04 -6.8 5.8 5.7e-09 -0.01 0.01 0.97 FALSE
40 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C20orf199 0.04 0.00 enet 8 0.02 6.4e-03 5.4 8.6 9.2e-18 0.62 0.01 0.50 FALSE
41 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C20orf199 0.05 0.06 lasso 4 0.06 1.0e-04 13.4 13.4 9.3e-41 0.92 0.00 0.96 FALSE
42 The Cancer Genome Atlas Testicular Germ Cell Tumors CSE1L 0.13 0.03 blup 50 0.07 1.4e-03 10.9 -10.0 1.5e-23 -0.60 0.03 0.27 FALSE
43 The Cancer Genome Atlas Thyroid Carcinoma ARFGEF2 0.06 0.01 blup 79 0.03 4.2e-04 -5.9 -8.1 5.8e-16 -0.42 0.75 0.05 FALSE
44 The Cancer Genome Atlas Thyroid Carcinoma DDX27 0.08 0.05 lasso 3 0.05 1.9e-05 13.3 11.6 7.1e-31 0.85 0.02 0.96 FALSE
45 The Cancer Genome Atlas Thyroid Carcinoma SLC9A8 0.21 0.12 blup 83 0.13 5.7e-13 -3.0 5.3 9.5e-08 -0.03 0.25 0.75 FALSE