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chr11:65,353,906-67,192,555

Best TWAS P=5.05e-12 · Best GWAS P=5.5e-12 conditioned to 0.0662

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTSF 0.09 0.06 enet 7 0.08 3.6e-07 -5.3 -5.4 5.3e-08 0.56 0.63 0.36 FALSE
2 GTEx Breast Mammary Tissue CTSF 0.18 0.10 lasso 6 0.08 6.6e-05 -5.2 -5.4 6.2e-08 0.52 0.33 0.19 FALSE
3 GTEx Breast Mammary Tissue B3GNT1 0.07 0.03 enet 9 0.05 1.6e-03 -5.3 6.9 5.0e-12 -0.78 0.07 0.73 TRUE
4 GTEx Lung SPTBN2 0.07 0.00 lasso 4 0.01 4.3e-02 -3.9 5.2 1.7e-07 -0.48 0.17 0.23 FALSE
5 GTEx Nerve Tibial B3GNT1 0.07 0.10 lasso 2 0.09 7.1e-07 -6.0 6.1 9.5e-10 -0.86 0.02 0.98 FALSE
6 GTEx Testis DPP3 0.10 0.06 lasso 4 0.07 5.3e-04 -6.0 -5.5 3.7e-08 0.83 0.05 0.71 FALSE
7 GTEx Thyroid BRMS1 0.05 0.02 lasso 4 0.01 2.6e-02 -5.3 6.0 2.4e-09 -0.61 0.08 0.40 FALSE
8 ROSMAP Brain Pre-frontal Cortex B3GNT1 0.04 0.02 lasso 2 0.02 1.3e-03 -6.0 6.2 5.4e-10 -0.87 0.03 0.88 FALSE
9 ROSMAP Brain Pre-frontal Cortex RIN1 0.03 0.03 enet 5 0.03 1.8e-04 -6.1 -6.2 6.5e-10 0.89 0.02 0.96 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CNIH2 0.03 0.00 enet 4 0.02 6.4e-03 5.5 -6.1 1.1e-09 0.57 0.06 0.18 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma C11orf80 0.05 0.04 lasso 3 0.03 4.6e-04 -5.3 5.4 7.7e-08 -0.56 0.01 0.99 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C11orf80 0.03 0.01 blup 30 0.01 4.8e-02 -5.3 5.7 1.4e-08 -0.55 0.01 0.74 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma SNX32 0.12 0.13 blup 60 0.13 1.2e-09 -4.0 -5.1 3.0e-07 0.07 0.01 0.74 TRUE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors NPAS4 0.14 0.14 blup 21 0.11 1.4e-04 -4.6 5.3 9.5e-08 -0.74 0.01 0.87 FALSE