Hub : Genes

CCR2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 NTR Blood 0.0399 0.0128 1.1e-06 0.026 0.022 0.030 0.024 0.026 5.3e-09 7.2e-08 5.9e-10 2.9e-08 6.9e-09
2 TCGA Prostate Adenocarcinoma 0.0958 0.0595 9.8e-04 0.010 0.039 0.049 NA 0.020 2.6e-02 6.1e-05 7.1e-06 NA 2.9e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.1 0.2 0.3 -0.2 -0.6
Bipolar Disorder or Schizophrenia 0.3 0.6 1.2 0.2 -1.1
Depressed Affect (Nagel 2018) 0.0 0.1 0.1 -0.3 0.1
Depression (Nagel 2018) 1.0 1.4 2.9 -1.7 0.1
Intelligence (Savage-Jansen 2018) 0.0 0.1 0.1 -0.1 -0.3
Neuroticism (Nagel 2018) 0.2 0.6 1.0 -1.0 -0.5
Schizophrenia (2018) 0.3 0.6 0.9 0.5 -0.9
Schizophrenia vs Biploar Disorder 0.1 0.2 0.4 0.6 0.1
Worry (Nagel 2018) 0.3 0.7 1.4 -1.2 0.0
Alzheimer’s Disease (in mother) 0.2 0.2 0.5 0.0 0.7
Alzheimer’s Disease (in father) 0.4 0.4 0.6 0.5 -0.8
Alzheimer’s Disease (including proxy) 0.1 0.2 0.2 -0.3 0.5
Crohns Disease (2017) 2.2 4.9 9.7 -3.1 0.3
Irritable Bowel Disease (IBD) 1.6 3.7 7.3 -2.7 -0.4
Ulcerative Colitis (UC) 0.5 0.9 1.2 -0.8 -1.1
Major Depression (MDD) 0.0 0.0 0.0 -0.0 -0.2
Reaction Time 0.1 0.1 0.2 -0.4 0.0
Verbal and Numeric Reasoning (VNR) 0.2 0.5 0.6 -0.6 0.8
Breast Cancer 0.1 0.3 0.7 -0.1 -0.8
Ovarian Cancer 1.5 2.0 2.5 -1.6 1.2
Prostate Cancer 0.2 0.2 0.5 0.1 -0.7
Age at First Birth 1.2 1.7 3.4 1.8 0.0
Bipolar Disorder (2011) 0.1 0.1 0.1 0.4 0.0
Body Mass Index (BMI) (2010) 0.8 1.1 2.1 -1.5 0.0
Coronary Artery Disease (CAD) 0.2 0.2 0.4 0.6 0.0
Crohns Disease (2012) 1.9 3.1 6.1 -2.5 0.2
Mean Putamen Volume 0.7 0.7 1.5 -0.2 -1.2
Fasting Glucose 1.0 1.1 2.1 -0.4 1.5
HbA1C 0.3 0.3 0.3 0.6 0.6
HDL Cholesterol 0.8 1.3 2.5 -1.6 0.0
LDL Cholesterol 0.9 1.5 3.0 1.7 0.0
Lupus 2.1 3.1 5.9 -2.4 0.7
Neuroticism (2016) 0.5 0.7 1.0 -0.6 1.0
Primary Biliary Cirrhosis 0.4 0.5 1.0 -1.0 -0.2
Rheumatoid Arthritis 0.0 0.0 0.0 0.0 0.0
Schizophrenia (2014) 0.2 0.5 0.7 -0.5 -0.9
Triglycerides 0.5 0.8 1.5 1.2 0.0
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.2 -0.4 0.0
Ulcerative Colitis 0.2 0.4 0.5 -0.7 0.5
Blood Eosinophil Count 1.2 9.0 15.5 3.9 -1.6
Blood Platelet Count 0.2 2.2 4.1 0.5 2.0
Blood Red Count 0.5 4.5 5.0 -2.0 -2.2
Blood White Count 0.8 5.8 9.1 -1.6 3.0
Heel T-Score 0.9 7.2 11.2 -3.4 -1.8
BMI 0.1 0.6 1.1 0.2 -1.0
Height 0.3 6.5 11.6 1.1 -3.4
Waist Hip Ratio (WHR) 0.3 1.3 1.7 -1.3 0.9
Systolic Blood Pressure 0.1 0.4 0.4 -0.6 0.6
Smoking Status 0.4 1.0 2.0 1.4 0.1
Allergy or Eczema 0.2 0.5 0.8 -0.9 -0.5
Cardiovascular Disease 0.5 1.7 3.2 0.5 -1.8
Hypothyroidism (self reported) 2.8 6.3 9.5 -3.1 -1.8
Respiratory disease 0.8 1.8 2.4 -1.1 -1.5
Type 2 Diabetes (T2D) (2018) 0.0 0.0 0.0 -0.1 0.2
Lung FEV1/FVC ratio 0.4 1.9 2.2 -1.3 1.5
Lung FVC 0.3 1.5 1.9 -1.4 1.1
Neuroticism 0.5 1.2 2.4 -1.6 -0.0
Chronotype (morning person) 3.3 7.7 9.1 -3.0 2.5
Hair Pigment 0.2 4.8 8.0 1.3 -2.8
Tanning 0.2 2.3 3.0 1.7 -1.3
Hand grip strength (left) 0.0 0.1 0.2 0.0 0.5
Number of treatments/medications taken 0.5 0.8 1.6 -1.3 -0.0
Average weekly spirits intake 0.4 0.6 0.7 0.7 0.8
Sensitivity / hurt feelings 0.0 0.1 0.1 0.3 0.1
Frequency of depressed mood in last 2 weeks 0.2 0.2 0.4 -0.6 0.2
Hearing difficulty/problems: Yes 0.3 0.5 0.8 -0.9 0.3
Relative age of first facial hair 0.3 0.6 0.8 0.7 -0.9
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 1.4 -0.4 -1.2
Ever used hormone-replacement therapy (HRT) 0.3 0.4 0.6 -0.7 -0.4
Ever had hysterectomy (womb removed) 0.4 0.5 1.0 1.0 0.1
Systolic blood pressure, automated reading 0.0 0.0 0.1 -0.2 0.2
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 0.7 0.4 -0.9
Angina 0.8 1.0 1.9 -0.4 -1.4
Medication for hormone replacement therapy 0.3 0.4 0.5 0.6 -0.7
Vitamin and mineral supplements 1.5 2.1 3.7 -1.9 0.6
Supplements: Zinc 1.0 1.1 1.4 0.9 1.2
Medication: Co-codamol 0.9 1.0 2.0 -1.4 0.0
Medication: Metformin 0.3 0.5 0.8 0.4 -0.9
Diabetes (father) 0.5 0.6 1.1 -0.1 -1.1
Diabetes (mother) 0.8 1.0 1.9 -1.4 0.2
Severe depression (siblings) 0.4 0.4 0.7 0.8 0.4
Pack years adult smoking proportion 0.5 0.8 1.2 -1.1 -0.6
Impedance of leg (right) 0.8 3.8 7.0 0.7 2.6
Leg fat-free mass (left) 0.8 4.4 8.7 0.4 -3.0
Trunk fat percentage 0.2 0.8 1.4 0.4 -1.2
Hand grip strength (right) 0.1 0.4 0.7 -0.3 0.8
Townsend deprivation index at recruitment 0.3 0.4 0.8 -0.9 0.0
Current tobacco smoking 0.7 1.1 2.1 -1.4 0.4
Average weekly fortified wine intake 2.2 2.6 3.0 1.7 -1.5
Maternal smoking around birth 0.6 0.8 0.9 -0.9 0.9
Fed-up feelings 0.5 0.9 1.1 -0.8 1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 3.2 4.3 7.5 -2.7 1.1
Relative age voice broke 0.5 0.8 1.0 0.7 -1.0
Taking other prescription medications 0.5 0.8 1.4 -1.2 -0.4
Age when periods started (menarche) 0.1 0.2 0.2 -0.4 0.5
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 0.7 -0.5 -0.8
Heel bone mineral density (BMD) T-score, automated (left) 2.1 4.7 9.3 -3.0 -0.2
Tinnitus: Yes, but not now, but have in the past 2.2 2.3 3.0 -1.7 -1.3
Qualifications: CSEs or equivalent 0.0 0.0 0.0 -0.1 -0.2
Serious illness, injury or assault to yourself 1.0 1.2 1.9 -0.7 1.4
High blood pressure 0.4 1.1 1.9 -0.6 -1.4
Hayfever, allergic rhinitis or eczema 0.5 1.0 1.7 0.5 -1.3
Multivitamins +/- minerals 0.1 0.1 0.1 -0.1 -0.3
Stomach or abdominal pain in last month 0.6 0.7 1.5 -0.1 1.2
Supplements: Glucosamine 1.6 2.2 2.4 1.5 -1.4
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 1.3 -1.1 -0.3
Medication: Atenolol 0.3 0.3 0.4 -0.6 0.5
Medication: Levothyroxine sodium 0.6 1.1 1.1 -1.1 -1.0
Sitting height 0.8 6.0 11.8 0.5 -3.4
Chronic bronchitis/emphysema (father) 0.2 0.2 0.3 -0.5 0.3
High blood pressure (mother) 1.0 1.3 1.5 1.1 -1.2
Body mass index (BMI) 0.2 1.0 1.7 -0.5 -1.3
Impedance of leg (left) 0.8 4.1 7.5 0.8 2.7
Leg predicted mass (left) 0.8 4.4 8.7 0.3 -3.0
Trunk fat mass 0.4 1.7 3.1 0.5 -1.8
Waist circumference 0.2 0.7 1.4 -0.2 -1.2
Number of incorrect matches in round 0.5 0.8 0.9 0.8 -1.0
Past tobacco smoking 0.2 0.4 0.8 -0.9 0.1
Alcohol usually taken with meals 1.8 2.8 4.0 1.3 -2.0
Nervous feelings 0.4 0.8 1.2 0.6 -1.1
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.1 -0.2 -0.3
Hearing difficulty/problems with background noise 0.1 0.2 0.3 -0.2 0.5
Hair/balding pattern: Pattern 2 0.1 0.1 0.2 0.2 0.4
Had menopause 0.4 0.5 0.6 -0.7 -0.7
Had other major operations 2.1 2.6 2.7 -1.6 1.6
Forced vital capacity (FVC) 0.0 0.0 0.0 -0.1 0.1
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 2.3 -1.5 -0.6
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 0.5 0.1 0.7
Qualifications: None of the above 0.0 0.0 0.0 0.2 0.2
Financial difficulties in last 2 years 1.1 1.5 2.2 -1.5 0.9
Mouth/teeth dental problems 7.6 11.6 22.5 -0.8 4.7
Heart attack 0.9 1.2 1.6 -0.8 1.3
Allergy 0.1 0.2 0.2 -0.4 0.5
Pain all over the body in last month 0.6 0.6 0.7 0.7 0.8
Diabetes (self-reported) 0.9 1.3 2.1 1.5 -0.7
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 0.5 -0.7 0.4
Medication: Ramipril 0.7 0.9 1.6 -0.5 1.3
Medication: Simvastatin 0.3 0.4 0.9 -0.1 -0.9
Fluid intelligence score 0.2 0.4 0.8 0.9 -0.3
Illnesses of siblings 0.6 0.8 0.9 0.9 0.9
Neuroticism score 0.2 0.4 0.8 -0.9 -0.0
Weight 0.6 2.9 5.7 0.1 -2.4
Impedance of arm (right) 0.2 0.7 0.9 0.9 0.8
Arm fat percentage (right) 0.3 1.1 2.1 0.2 -1.5
Trunk fat-free mass 0.5 2.8 5.5 0.5 -2.3
Hip circumference 0.5 2.0 2.5 1.2 -1.6
Time employed in main current job 1.1 1.3 1.4 1.2 1.1
Alcohol intake versus 10 years previously 0.0 0.0 0.0 0.1 0.0
Father’s age at death 2.0 2.6 5.2 -2.3 0.2
Worrier / anxious feelings 1.9 3.6 7.1 -2.7 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 0.8 -0.9 -0.9
Falls in the last year 1.1 1.4 2.7 -0.4 1.6
Hair/balding pattern: Pattern 3 0.4 0.6 1.1 -1.1 0.0
Number of live births 0.2 0.3 0.5 0.0 -0.7
Forced expiratory volume in 1-second (FEV1) 0.1 0.5 0.6 -0.6 0.8
Pulse rate 0.1 0.2 0.2 -0.4 -0.4
Happiness 0.5 0.6 0.8 -0.9 0.7
Noisy workplace 2.9 3.6 5.5 -2.4 1.3
Qualifications: A levels/AS levels or equivalent 0.5 1.1 1.2 1.1 -1.0
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 0.6 0.3 -0.8
Mouth/teeth dental problems: Dentures 0.3 0.5 0.8 -0.9 -0.3
Asthma 0.3 0.6 0.7 -0.6 -0.9
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 0.4 0.7 0.4
Medication: Cholesterol lowering 1.4 2.2 2.7 1.3 -1.6
Depression (self-reported) 3.0 3.5 6.8 0.5 -2.6
Medication: Lansoprazole 0.2 0.2 0.3 -0.6 -0.3
Prospective memory result 0.7 0.8 1.2 0.6 1.1
Lung cancer (father) 1.7 2.0 4.0 0.3 -2.0
Illnesses of mother 0.4 0.4 0.6 0.5 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.0 0.0 0.1 -0.1 -0.3
Pulse wave Arterial Stiffness index 0.4 0.5 1.0 -0.0 1.0
Impedance of arm (left) 0.2 0.7 0.8 0.9 0.8
Arm fat mass (right) 0.4 1.8 3.5 0.4 -1.9
Trunk predicted mass 0.5 2.7 5.2 0.5 -2.3
Standing height 0.4 4.2 6.8 1.2 -2.6
Length of working week for main job 0.8 0.9 1.8 -1.4 0.1
Exposure to tobacco smoke at home 0.9 1.0 1.8 0.5 1.4
Breastfed as a baby 0.2 0.3 0.5 0.7 -0.2
Tense / ‘highly strung’ 0.2 0.3 0.6 -0.7 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.2 0.4 0.6 0.0
Hair/balding pattern: Pattern 4 0.1 0.3 0.3 -0.5 0.6
Birth weight of first child 0.1 0.3 0.5 0.7 -0.3
Peak expiratory flow (PEF) 0.6 1.5 2.5 -1.6 0.7
Pulse wave reflection index 0.7 0.8 1.3 0.6 1.2
Ever highly irritable/argumentative for 2 days 0.3 0.4 0.6 -0.8 0.4
Loud music exposure frequency 1.0 1.1 2.2 -0.1 1.5
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.1 -0.2 -0.4
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.2 0.4 0.0
Blood clot in the leg (DVT) 0.4 0.5 0.6 0.6 0.8
Medication: Paracetamol 4.0 6.6 8.4 -2.9 2.2
Headache pain in last month 0.3 0.4 0.6 -0.5 -0.8
Medication for cholesterol, blood pressure or diabetes 0.7 1.2 2.4 -0.1 1.6
Glaucoma (self-reported) 0.6 0.7 0.8 -0.8 0.9
Gout (self-reported) 0.6 0.8 1.0 0.7 1.0
Hypothyroidism/myxoedema (self-reported) 1.7 3.3 4.2 -2.0 -1.5
Medication: Amlodipine 3.8 5.3 9.9 -3.1 0.8
Medication: Ventolin 100micrograms inhaler 0.6 0.7 0.9 -0.7 0.9
Birth weight 0.6 1.2 2.2 1.5 0.5
Chronic bronchitis/emphysema (mother) 0.6 0.7 1.3 -1.1 0.4
High blood pressure (siblings) 0.4 0.5 0.9 0.3 -1.0
Forced vital capacity (FVC), Best measure 0.1 0.3 0.4 0.3 -0.6
Body fat percentage 0.1 0.4 0.8 0.2 -0.9
Leg fat percentage (right) 0.0 0.1 0.1 0.1 -0.3
Arm fat-free mass (right) 0.6 2.9 5.8 0.2 -2.4
Exposure to tobacco smoke outside home 2.2 3.0 6.0 -2.4 0.1
Comparative body size at age 10 0.4 1.2 2.0 -1.4 -0.6
Number of full brothers 0.6 0.8 1.4 1.2 -0.3
Worry too long after embarrassment 0.4 0.7 1.2 -1.1 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.1 3.4 -0.9 -1.8
Wheeze or whistling in the chest in last year 0.9 1.5 2.7 -1.6 -0.6
Number of children fathered 0.4 0.5 0.7 -0.8 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.1 0.2 -0.4 0.1
Age at first live birth 0.4 0.7 1.1 0.6 1.1
Pulse wave peak to peak time 0.6 0.8 1.5 0.0 -1.2
Health satisfaction 0.3 0.4 0.7 -0.2 0.8
Shortness of breath walking on level ground 0.4 0.4 0.8 0.2 0.9
Qualifications: College or University degree 0.0 0.1 0.1 0.0 -0.3
Eye problems/disorders: None of the above 0.3 0.4 0.7 0.1 -0.9
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.2 -0.4 -0.5
Emphysema/chronic bronchitis 2.2 2.4 4.5 -2.1 -0.6
Medication for pain relief, constipation, heartburn 2.5 4.2 6.1 2.5 -1.5
Neck or shoulder pain in last month 0.1 0.1 0.3 -0.5 -0.2
Medication: Blood pressure 0.2 0.3 0.5 -0.7 -0.1
Angina (self-reported) 0.9 1.2 2.4 -0.1 -1.6
Migraine (self-reported) 0.1 0.1 0.3 -0.0 0.5
Medication: Ibuprofen 0.4 0.5 0.8 0.9 0.5
Medication: Allopurinol 0.1 0.1 0.3 -0.0 0.5
Medication: Omeprazole 2.0 2.4 3.4 -1.8 1.2
Medication: Seretide 50 evohaler 3.7 4.3 8.4 2.9 0.4
Mean time to correctly identify matches 0.2 0.3 0.4 -0.7 0.4
Heart disease (mother) 0.2 0.3 0.6 -0.8 0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 1.1 -0.7 1.1
Whole body fat mass 0.3 1.1 2.1 0.2 -1.4
Leg fat mass (right) 0.2 0.7 1.2 0.4 -1.1
Arm predicted mass (right) 0.5 2.5 4.9 0.2 -2.2
Pulse rate, automated reading 0.4 1.3 2.7 -0.2 -1.6
Alcohol intake frequency. 1.3 3.0 4.8 -2.2 1.1
Comparative height size at age 10 0.0 0.1 0.1 -0.1 -0.4
Number of full sisters 1.7 2.0 3.6 -0.6 -1.9
Suffer from ‘nerves’ 0.7 1.1 1.5 0.9 -1.2
Overall health rating 1.8 3.9 6.2 -2.5 1.3
Chest pain or discomfort 0.0 0.0 0.0 -0.1 0.2
Had major operations 0.1 0.1 0.1 0.2 -0.4
Age at last live birth 0.7 1.0 1.7 1.3 -0.6
Family relationship satisfaction 1.2 1.5 2.1 -1.4 0.9
Leg pain on walking 0.7 0.8 1.3 -1.1 0.6
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 1.4 -1.1 -1.2
Commuting to job workplace: Car/motor vehicle 3.4 3.9 7.8 2.8 0.2
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.3 0.5 0.0
Medication: Aspirin 0.6 0.8 1.3 -1.1 -0.5
Supplements: Vitamin C 5.5 6.5 11.4 3.4 -1.3
Knee pain experienced in last month 0.4 0.6 1.2 -1.1 0.2
Hypertension (Self-reported) 0.4 1.0 1.0 -1.0 -1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 3.7 4.3 6.0 -2.5 1.6
Illnesses of father: Heart disease 0.2 0.3 0.4 -0.4 0.6
Illnesses of siblings: Diabetes 1.3 1.5 1.9 -1.1 -1.4
Smoking status: Previous 0.4 0.6 1.2 1.1 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.1 0.2 -0.5 -0.2
Whole body fat-free mass 0.6 3.6 6.9 0.4 -2.6
Leg fat-free mass (right) 1.1 5.6 10.9 0.6 -3.3
Arm fat percentage (left) 0.2 0.8 1.6 0.2 -1.2
Average weekly red wine intake 0.8 1.2 2.0 -0.7 -1.4
Handedness (chirality/laterality): Left-handed 1.0 1.2 1.2 -1.1 -1.1
Mood swings 0.0 0.0 0.0 0.1 -0.2
Loneliness, isolation 0.5 0.7 0.7 -0.8 0.8
Long-standing illness, disability or infirmity 0.6 0.9 1.0 -1.0 0.9
Ever had bowel cancer screening 0.1 0.1 0.2 -0.3 -0.4
Diabetes diagnosed by doctor 0.3 0.4 0.6 0.8 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 1.3 1.1 0.2
Friendships satisfaction 0.4 0.5 0.7 -0.8 0.5
Qualifications: nursing, teaching 1.7 2.6 3.6 1.9 -1.2
Commuting to job workplace: Walk 1.4 1.5 2.1 -1.4 0.9
Eye problems/disorders: Cataract 0.3 0.3 0.5 -0.4 0.7
Mouth/teeth dental problems: Mouth ulcers 52.0 82.7 148.8 4.1 -12.2
Medication for cholesterol 0.3 0.4 0.9 0.9 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 1.8 -1.3 -0.3
Back pain experienced in last month 0.9 1.3 1.9 -1.4 0.8
Mineral and other dietary supplements 0.2 0.3 0.4 -0.5 0.6
Breast cancer (self-reported) 0.1 0.2 0.3 0.1 0.5
Asthma (self-reported) 0.3 0.5 0.6 -0.7 -0.7
Osteoporosis (self-reported) 0.1 0.2 0.3 0.2 0.6
Osteoarthritis (self-reported) 1.2 1.6 3.0 -1.7 -0.4
Medication: Aspirin 0.2 0.2 0.2 -0.4 -0.4
Medication: Gliclazide 0.8 0.9 1.3 -1.1 0.7
Illnesses of father: None of the above (group 1) 0.3 0.4 0.8 0.9 0.1
Smoking status: Current 0.5 0.8 1.3 -1.2 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 0.7 -0.8 -0.3
Whole body water mass 0.7 4.1 8.1 0.3 -2.8
Leg predicted mass (right) 1.0 5.2 10.1 0.6 -3.2
Arm fat mass (left) 0.4 1.8 3.3 0.6 -1.8
Number of self-reported non-cancer illnesses 0.9 1.5 3.0 -0.1 -1.7
Average weekly champagne plus white wine intake 0.7 1.0 1.8 0.3 1.4
Miserableness 0.2 0.3 0.7 -0.8 0.1
Guilty feelings 0.2 0.3 0.3 -0.5 -0.5
Wears glasses or contact lenses 0.3 0.3 0.6 -0.8 0.1
Ever taken oral contraceptive pill 0.7 0.8 1.4 -0.4 -1.2
Hearing aid user 0.4 0.4 0.6 -0.5 -0.8
Mother’s age at death 0.4 0.5 0.5 0.7 -0.6
Financial situation satisfaction 2.5 3.1 3.4 -1.7 1.8
Tinnitus: Yes, now most or all of the time 3.4 4.0 6.2 -1.3 2.5
Commuting to job workplace: Public transport 1.4 1.7 3.3 -1.8 -0.3
Eye problems/disorders: Glaucoma 0.4 0.5 0.5 -0.7 0.7
Medication: Blood pressure 0.9 1.7 3.4 -1.9 0.1
Pain type(s) experienced in last month: Hip pain 1.2 1.5 1.9 -1.4 1.1
Supplements: Fish oil (including cod liver oil) 0.2 0.2 0.5 0.0 -0.7
High cholesterol (Self-reported) 1.5 2.7 5.3 0.2 -2.3
Medication: Bendroflumethiazide 0.1 0.1 0.2 -0.5 0.2
Medication: Paracetamol 3.2 5.0 7.0 -2.6 1.8
Medication: Lisinopril 0.8 1.0 1.4 -0.8 -1.2
Medication: Atorvastatin 1.3 1.6 3.1 -0.4 -1.7
Illnesses of father: High blood pressure 0.9 1.1 1.6 -0.8 -1.3
Alcohol drinker status: Never 2.9 3.4 6.6 -2.6 -0.5
Ever smoked 0.1 0.2 0.2 0.4 0.4
Basal metabolic rate 0.7 3.7 7.2 0.4 -2.7
Leg fat percentage (left) 0.0 0.1 0.2 0.2 -0.4
Arm fat-free mass (left) 0.4 2.1 4.3 0.0 -2.1
Number of operations (self-reported) 1.2 1.7 3.4 -1.9 0.2
Average weekly beer plus cider intake 0.2 0.3 0.4 -0.4 0.6
Irritability 0.6 0.9 1.6 -1.2 0.6
Risk taking 0.1 0.1 0.1 0.2 -0.4
Ever had prostate specific antigen (PSA) test 1.0 1.1 2.2 -0.1 -1.5
Fractured/broken bones in last 5 years 0.9 1.1 2.3 1.5 -0.1
Age started oral contraceptive pill 1.4 1.8 2.6 -1.6 -0.9
Diastolic blood pressure, automated reading 0.0 0.1 0.3 0.1 -0.5
Ever depressed for a whole week 1.0 1.2 2.0 1.4 0.6
Unable to work because of sickness or disability 0.8 1.0 1.5 0.6 1.2
Commuting to job workplace: Cycle 0.4 0.5 1.0 -0.1 1.0
Myopia 0.7 1.0 1.4 -1.2 -0.8
Vascular/heart problems diagnosed by doctor 0.5 1.4 2.0 0.9 1.4
Cholesterol lowering medication 1.0 1.5 2.0 -1.4 -0.9
Medication: Omeprazole (e.g. Zanprol) 3.5 4.2 5.6 -2.4 1.7
Pain experienced in last month 1.1 1.9 2.1 1.3 -1.4
Supplements: Calcium 0.0 0.0 0.0 0.2 0.2
Basal cell carcinoma (self-reported) 0.2 0.3 0.6 -0.8 0.0
Heart attack/myocardial infarction (self-reported) 1.1 1.4 1.6 -1.1 1.3
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 0.9 0.8 0.9
Heart disease (siblings) 0.6 0.7 0.7 -0.8 0.8
Alcohol drinker status: Previous 2.4 2.7 4.6 -0.9 2.1
Pack years of smoking 0.7 1.0 1.4 -1.2 -0.7
Impedance of whole body 0.4 2.1 3.2 1.0 1.8
Leg fat mass (left) 0.2 0.8 1.4 0.5 -1.2
Arm predicted mass (left) 0.4 2.2 4.5 -0.0 -2.1