[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr10:103,313,599-105,850,787

Best TWAS P=2.13e-15 · Best GWAS P=1.2e-16 conditioned to 0.00407

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Testis	NT5C2	0.20	0.03	lasso	8	0.08	2.8e-04	7.2	7.9	2.1e-15	0.86	0.04	0.91	TRUE
9	YFS	Blood	NT5C2	0.13	0.10	bslmm	382	0.11	7.3e-35	8.1	7.7	1.0e-14	0.94	0.01	0.99	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	CNNM2	0.11	0.08	lasso	3	0.07	2.2e-09	7.6	7.6	2.8e-14	0.99	0.02	0.98	FALSE
5	GTEx	Testis	CYP17A1-AS1	0.14	0.08	enet	5	0.10	2.3e-05	7.1	-7.2	4.2e-13	-0.97	0.05	0.93	FALSE
3	GTEx	Cells Transformed fibroblasts	SUFU	0.07	0.04	lasso	3	0.04	3.5e-04	7.2	7.0	1.8e-12	0.83	0.38	0.16	FALSE
10	The Cancer Genome Atlas	Stomach Adenocarcinoma	AS3MT	0.05	0.02	blup	62	0.03	2.1e-03	-2.7	6.3	4.0e-10	0.72	0.02	0.32	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	USMG5	0.04	0.03	lasso	9	0.03	1.6e-04	3.6	-6.0	1.7e-09	-0.64	0.04	0.94	FALSE
6	GTEx	Thyroid	WBP1L	0.26	0.10	enet	9	0.13	2.1e-10	3.9	-6.0	2.3e-09	-0.80	0.66	0.34	FALSE
1	GTEx	Breast Mammary Tissue (Female)	CYP17A1-AS1	0.14	0.01	lasso	11	0.00	4.7e-01	7.2	5.4	8.1e-08	0.87	0.03	0.61	FALSE
2	GTEx	Cells Transformed fibroblasts	GBF1	0.07	0.00	enet	2	0.00	1.4e-01	5.1	5.2	2.5e-07	0.78	0.05	0.47	FALSE