TWAS hub - USMG5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0280	0.0140	0.01300	0.009	0.004	0.000	0.005	0.001	2.8e-02	1.1e-01	0.3200	0.0750	0.21000
2	ROSMAP	Brain Pre-frontal Cortex	0.0414	0.0171	0.00076	0.034	0.016	0.013	0.018	0.027	2.8e-05	3.6e-03	0.0072	0.0021	0.00016
3	YFS	Blood	0.4975	0.0393	0.00000	0.712	0.684	0.712	0.709	0.714	0.0e+00	6.3e-318	0.0000	0.0000	0.00000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Systolic blood pressure, automated reading	19.1	55.4	79.0	7.2	8.9	-6.0
Birth weight	18.8	40.9	46.2	-6.7	-6.8	5.7
Systolic Blood Pressure	18.0	90.2	139.2	9.0	11.8	-7.0
Age at First Birth	9.2	13.4	13.8	-3.6	-3.7	3.7
Tense / ‘highly strung’	8.5	14.0	18.0	4.2	4.0	-2.8
Age at first live birth	8.3	14.8	15.7	-3.6	-3.9	4.0
Worry (Nagel 2018)	7.9	16.6	23.0	4.4	4.8	-2.7
Coronary Artery Disease (CAD)	7.9	9.4	11.7	3.4	3.4	-2.3
Medication: Blood pressure	7.7	14.6	22.1	3.6	4.7	-3.0
Vascular/heart problems diagnosed by doctor	7.7	20.9	36.2	-3.7	-6.0	3.6
Schizophrenia (2018)	7.6	15.7	24.6	3.8	5.0	-2.8
Schizophrenia vs Biploar Disorder	7.5	9.9	13.0	3.6	3.4	-2.2
Diastolic blood pressure, automated reading	7.4	23.0	30.8	5.2	5.5	-3.3
Neck or shoulder pain in last month	7.2	10.3	13.5	2.9	3.7	-2.9
Angina (self-reported)	7.2	9.5	11.4	3.2	3.4	-2.6
Serious illness, injury or assault to yourself	7.0	8.5	9.0	3.0	3.0	-2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	6.6	10.1	11.3	3.3	3.4	-2.8
High blood pressure	6.5	18.0	32.4	3.3	5.7	-3.3
Nervous feelings	6.4	11.9	17.1	3.5	4.1	-2.5
Impedance of leg (right)	6.3	30.8	41.4	5.6	6.4	-4.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	6.2	13.1	14.2	3.8	3.7	-3.4
Neuroticism	6.1	14.6	20.6	3.8	4.5	-2.9
Worry too long after embarrassment	6.0	10.0	13.3	2.5	3.7	-3.2
Hypertension (Self-reported)	6.0	16.7	29.9	3.2	5.5	-3.1
Crohns Disease (2012)	5.9	9.5	11.5	3.0	2.8	-3.4
Cardiovascular Disease	5.7	18.8	34.5	3.6	5.9	-3.0
Illness, injury, bereavement, stress in last 2 years	5.7	6.9	8.9	-2.3	-3.0	2.5
Schizophrenia (2014)	5.6	12.4	21.3	3.3	4.6	-2.2
Impedance of leg (left)	5.6	27.1	38.1	5.2	6.2	-4.0
Heart attack	5.6	7.2	8.9	3.0	2.9	-2.0
Pack years adult smoking proportion	5.5	8.3	12.4	2.1	2.9	-3.5
Pain type(s) experienced in last month: Hip pain	5.5	6.9	7.4	2.7	2.5	-2.7
Angina	5.3	7.0	8.4	2.8	2.9	-2.2
Past tobacco smoking	5.2	9.6	15.2	-2.3	-2.9	3.9
Smoking status: Previous	5.2	7.7	10.2	2.2	2.8	-3.2
Fractured/broken bones in last 5 years	5.2	6.7	8.1	2.4	2.8	-2.5
Pack years of smoking	5.1	7.5	11.4	1.8	2.8	-3.4
High blood pressure (mother)	5.0	7.0	10.3	2.8	3.2	-1.7
Heart attack/myocardial infarction (self-reported)	4.9	6.3	8.2	2.9	2.7	-1.8
Illnesses of father: None of the above (group 1)	4.7	5.8	7.9	-2.3	-2.8	2.0
Bipolar Disorder or Schizophrenia	4.6	11.2	19.8	3.1	4.5	-2.0
Average weekly spirits intake	4.6	5.7	8.7	2.2	1.9	-2.9
Major Depression (MDD)	4.5	5.5	8.1	2.3	2.8	-1.8
Severe depression (siblings)	4.5	5.1	7.8	1.8	2.8	-2.0
Financial difficulties in last 2 years	4.4	6.0	7.7	2.0	2.5	-2.8
Age at last live birth	4.4	6.4	7.4	-2.2	-2.6	2.7
Neuroticism (Nagel 2018)	4.3	10.1	15.3	2.9	3.9	-2.5
Smoking Status	4.3	10.3	19.4	2.2	2.6	-4.4
Medication: Atenolol	4.3	5.3	6.7	2.5	2.6	-1.8
Chronotype (morning person)	4.2	9.7	12.1	-2.8	-3.0	3.5
Time employed in main current job	4.1	4.7	7.0	-1.6	-2.1	2.6
Ever smoked	4.1	7.2	12.0	2.0	2.4	-3.5
Birth weight of first child	3.9	7.2	9.2	-2.6	-3.0	2.4
Medication: Co-codamol	3.8	4.5	4.7	2.2	2.1	-2.0
Frequency of tenseness / restlessness in last 2 weeks	3.7	5.8	10.4	2.0	3.2	-1.8
Medication: Paracetamol	3.7	6.1	6.8	2.5	2.6	-2.2
Migraine (self-reported)	3.7	4.5	7.6	-1.8	-2.8	1.6
Current tobacco smoking	3.6	5.9	9.7	2.1	1.9	-3.1
Glaucoma (self-reported)	3.5	4.1	5.5	2.4	1.9	-1.7
Relative age voice broke	3.4	5.2	6.6	1.9	2.3	-2.6
Blood White Count	3.3	24.8	28.6	5.1	5.3	-4.4
Lung FVC	3.3	17.0	20.2	4.3	4.5	-3.5
Lung cancer (father)	3.3	3.9	5.5	-1.8	-2.3	1.7
Back pain experienced in last month	3.3	4.8	5.7	2.4	2.2	-2.0
Sensitivity / hurt feelings	3.2	5.4	7.6	1.9	2.8	-2.2
Illnesses of mother	3.2	3.9	5.2	-2.0	-2.3	1.6
Illnesses of father: High blood pressure	3.2	3.9	6.8	1.3	2.6	-1.8
Alcohol intake versus 10 years previously	3.0	4.5	6.8	1.9	1.8	-2.6
Leg fat-free mass (right)	3.0	15.9	23.9	-4.2	-4.9	2.4
Leg predicted mass (right)	3.0	16.2	24.3	-4.3	-4.9	2.5
Pulse wave reflection index	2.9	3.6	4.6	-2.1	-2.1	1.3
Average weekly champagne plus white wine intake	2.9	4.0	5.7	-1.7	-2.4	1.9
Eye problems/disorders: Glaucoma	2.9	3.4	4.9	2.2	1.6	-1.6
Medication: Paracetamol	2.9	4.5	5.4	2.2	2.3	-1.9
Cholesterol lowering medication	2.8	4.1	5.3	2.0	2.3	-1.8
Leg fat-free mass (left)	2.7	14.1	22.0	-4.0	-4.7	2.1
Illnesses of siblings: Diabetes	2.7	3.4	4.7	-1.6	-2.2	1.6
Wheeze or whistling in the chest in last year	2.6	4.6	6.4	-1.5	-2.5	2.2
Supplements: Calcium	2.6	2.9	3.9	2.0	1.5	-1.6
Leg predicted mass (left)	2.5	13.4	21.0	-3.9	-4.6	2.0
Forced expiratory volume in 1-second (FEV1)	2.5	8.3	8.6	2.8	2.9	-2.9
Medication: Seretide 50 evohaler	2.5	2.9	4.6	-2.1	-1.6	1.1
Suffer from ‘nerves’	2.5	4.0	6.5	2.0	2.5	-1.3
Had major operations	2.5	2.9	4.8	1.4	1.5	-2.2
Family relationship satisfaction	2.5	3.1	4.4	0.9	2.0	-2.1
Heel T-Score	2.4	18.8	24.6	-4.1	-5.0	3.9
Maternal smoking around birth	2.4	3.5	4.6	2.0	1.4	-2.2
Medication for cholesterol	2.4	3.7	6.7	-1.6	-2.6	1.3
Smoking status: Current	2.4	3.8	6.9	1.5	1.4	-2.6
Impedance of whole body	2.4	12.3	18.2	3.5	4.3	-2.5
Relative age of first facial hair	2.3	4.7	7.5	1.5	2.0	-2.7
Forced vital capacity (FVC)	2.3	8.8	10.0	2.8	3.2	-2.9
Neuroticism score	2.3	4.7	7.2	2.1	2.7	-1.6
Medication: Atorvastatin	2.3	2.8	4.8	1.3	2.2	-1.3
Ever had prostate specific antigen (PSA) test	2.2	2.6	4.1	-1.2	-1.5	2.0
Heart disease (siblings)	2.2	2.7	4.8	1.3	2.2	-1.2
Depression (Nagel 2018)	2.1	3.1	5.0	1.6	2.2	-1.4
Number of live births	2.1	2.9	4.2	2.1	1.9	-1.0
Risk taking	2.1	3.1	3.4	1.8	1.6	-1.9
Falls in the last year	2.0	2.7	4.6	2.1	1.6	-1.1
Medication: Ibuprofen	2.0	2.5	4.4	2.1	1.0	-1.4
Illnesses of father: Heart disease	2.0	2.8	4.9	1.5	2.2	-1.1
Medication: Bendroflumethiazide	2.0	3.0	5.3	1.4	2.3	-1.4
Osteoarthritis (self-reported)	1.9	2.5	3.3	1.5	1.8	-1.4
Average weekly beer plus cider intake	1.9	2.7	3.6	-1.9	-1.6	1.4
Intelligence (Savage-Jansen 2018)	1.8	5.5	6.4	-2.1	-2.4	2.5
Primary Biliary Cirrhosis	1.8	2.6	2.9	1.7	1.4	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.8	6.5	2.5	2.4	-2.3
Length of working week for main job	1.8	2.0	2.8	1.2	1.3	-1.7
Ever highly irritable/argumentative for 2 days	1.8	2.2	3.8	0.9	1.9	-1.3
Forced vital capacity (FVC), Best measure	1.8	6.5	6.7	2.6	2.6	-2.5
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	3.2	-1.5	-1.7	1.8
Breast cancer (self-reported)	1.8	2.1	3.0	-1.0	-1.6	1.7
Allergy or Eczema	1.7	4.6	5.2	-2.3	-2.1	2.0
Whole body fat-free mass	1.7	9.6	14.6	-3.4	-3.8	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	2.6	1.6	1.2	-1.4
Irritability	1.7	2.8	3.6	1.9	1.6	-1.5
Stomach or abdominal pain in last month	1.6	2.0	2.3	-1.3	-1.5	1.4
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	2.2	-1.4	-1.4	1.5
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.1	3.7	1.9	1.0	-1.2
Shortness of breath walking on level ground	1.6	1.9	2.6	-1.1	-1.4	1.6
Medication: Allopurinol	1.6	2.2	3.2	1.1	1.8	-1.5
Whole body water mass	1.6	9.1	13.9	-3.4	-3.7	1.5
Basal metabolic rate	1.6	8.6	13.6	-3.2	-3.7	1.4
Alzheimer’s Disease (in father)	1.5	1.6	2.2	-1.3	-1.0	1.5
Ulcerative Colitis (UC)	1.5	2.8	4.2	-1.2	-1.7	2.0
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	2.4	1.1	1.6	-1.3
Hair/balding pattern: Pattern 4	1.5	3.7	4.7	-1.5	-2.2	2.1
Verbal and Numeric Reasoning (VNR)	1.4	3.3	4.4	-1.4	-2.1	1.9
Respiratory disease	1.4	3.2	3.6	-1.9	-1.9	1.6
Number of treatments/medications taken	1.4	2.4	4.2	1.3	2.1	-1.2
Qualifications: None of the above	1.4	3.0	3.7	1.4	1.8	-1.9
Long-standing illness, disability or infirmity	1.4	2.1	2.9	1.3	1.7	-1.3
Bipolar Disorder (2011)	1.3	1.2	3.3	0.3	1.8	-0.5
Average weekly fortified wine intake	1.3	1.6	1.7	-1.1	-1.3	1.3
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	2.3	0.9	1.0	-1.5
Medication: Ramipril	1.3	1.6	2.9	1.2	1.7	-0.7
HDL Cholesterol	1.2	1.9	2.6	1.0	1.6	-1.5
BMI	1.2	6.9	12.5	-2.7	-3.5	1.0
Hayfever, allergic rhinitis or eczema	1.2	2.6	2.9	-1.7	-1.5	1.6
Supplements: Glucosamine	1.2	1.5	1.8	1.3	1.0	-1.3
Illnesses of siblings	1.2	1.7	2.8	-1.1	-1.7	1.1
High blood pressure (siblings)	1.2	1.7	3.6	0.9	1.9	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	3.3	0.8	1.8	-0.7
Ever depressed for a whole week	1.2	1.4	2.9	0.4	1.7	-1.1
Breast Cancer	1.1	2.5	3.0	-1.7	-1.5	1.5
Hair/balding pattern: Pattern 2	1.1	1.3	2.0	-1.3	-1.4	0.7
Fluid intelligence score	1.1	2.2	3.7	-1.1	-1.9	1.3
Trunk predicted mass	1.1	6.3	9.4	-2.9	-3.1	1.1
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.4	-1.5	-1.1	0.8
Medication: Lisinopril	1.1	1.4	3.4	0.0	1.8	-0.9
Crohns Disease (2017)	1.0	2.2	3.0	1.3	1.4	-1.7
Waist Hip Ratio (WHR)	1.0	4.3	5.0	1.9	2.2	-2.1
Diabetes (father)	1.0	1.2	1.7	1.1	0.8	-1.3
Trunk fat-free mass	1.0	6.0	8.9	-2.8	-3.0	1.1
Peak expiratory flow (PEF)	1.0	2.3	3.9	1.4	1.1	-2.0
Medication for pain relief, constipation, heartburn	1.0	1.8	2.3	-1.5	-1.5	0.9
Chest pain or discomfort	1.0	1.4	2.7	0.6	1.6	-1.1
Friendships satisfaction	1.0	1.3	2.0	-1.4	-1.1	0.7
Osteoporosis (self-reported)	1.0	1.3	1.9	0.9	1.4	-1.1
Arm fat-free mass (left)	1.0	5.1	8.0	-2.5	-2.8	0.9
Unable to work because of sickness or disability	1.0	1.3	2.4	0.9	1.5	-0.9
Ever had hysterectomy (womb removed)	0.9	1.0	1.4	-0.7	-1.0	1.2
Vitamin and mineral supplements	0.9	1.2	2.1	-1.5	-0.8	1.0
Hair/balding pattern: Pattern 3	0.9	1.3	2.8	0.6	1.7	-1.0
Exposure to tobacco smoke outside home	0.9	1.3	2.9	0.7	0.6	-1.7
Number of full brothers	0.9	1.1	1.5	1.0	1.2	-1.0
Alcohol intake frequency.	0.9	2.0	2.4	1.2	1.4	-1.6
Commuting to job workplace: Walk	0.9	0.9	1.9	0.8	1.4	-0.5
Pain experienced in last month	0.9	1.5	2.6	-1.6	-1.1	0.7
Arm predicted mass (left)	0.9	4.5	7.4	-2.4	-2.7	0.7
Qualifications: CSEs or equivalent	0.8	1.1	1.3	-1.0	-1.1	0.9
Had menopause	0.8	1.0	1.6	0.9	1.3	-0.6
Weight	0.8	4.1	7.3	-2.2	-2.7	0.5
Health satisfaction	0.8	1.1	1.2	1.0	1.0	-1.1
Overall health rating	0.8	1.7	2.0	1.1	1.4	-1.4
Commuting to job workplace: Cycle	0.8	0.9	1.5	0.7	1.2	-0.9
Basal cell carcinoma (self-reported)	0.8	0.9	1.2	-0.8	-0.9	1.1
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	1.0	0.8	0.9	-1.0
Supplements: Zinc	0.7	0.8	1.1	1.1	0.6	-0.9
Hand grip strength (right)	0.7	1.8	3.4	1.3	0.6	-1.8
Body mass index (BMI)	0.7	3.1	6.0	-1.7	-2.5	0.6
Hip circumference	0.7	2.9	5.1	-1.9	-2.3	0.3
Arm fat mass (right)	0.7	3.0	5.7	-1.7	-2.4	0.6
Arm fat-free mass (right)	0.7	3.8	6.1	-2.3	-2.5	0.6
Heart disease (mother)	0.7	0.8	1.6	0.6	1.2	-0.7
Arm predicted mass (right)	0.7	3.6	5.6	-2.2	-2.4	0.5
Comparative height size at age 10	0.7	4.0	8.5	-2.9	-1.8	0.3
Financial situation satisfaction	0.7	0.8	1.9	-1.4	-0.7	0.1
Lupus	0.6	0.9	1.9	-1.4	-0.7	0.4
Rheumatoid Arthritis	0.6	0.8	1.0	0.7	0.9	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	1.7	-1.2	-1.3	0.9
Worrier / anxious feelings	0.6	1.2	2.9	0.8	1.7	0.2
Impedance of arm (left)	0.6	3.0	4.5	1.9	2.1	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	0.7	0.8	0.7	-0.8
Arm fat mass (left)	0.6	2.5	5.1	-1.5	-2.2	0.4
Body Mass Index (BMI) (2010)	0.5	0.6	1.4	-0.4	-1.2	-0.5
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.5	0.5	1.2	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.0	0.6	1.0	-0.9
Trunk fat mass	0.5	2.1	4.1	-1.4	-2.0	0.1
Impedance of arm (right)	0.5	2.5	3.7	1.8	1.9	-0.8
Arm fat percentage (right)	0.5	2.0	4.1	-1.3	-2.0	0.5
Loud music exposure frequency	0.5	0.5	0.9	0.5	0.6	-1.0
Medication: Amlodipine	0.5	0.7	1.7	0.7	1.3	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.2	-0.3	1.1	-0.6
Eye problems/disorders: None of the above	0.5	0.6	1.0	-0.3	-1.0	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.0	0.3	0.9	-1.0
Pulse rate, automated reading	0.5	1.7	2.6	1.6	1.6	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.2	0.3	1.1	-0.6
Mood swings	0.5	0.9	1.7	-0.7	-0.6	1.3
Mineral and other dietary supplements	0.5	0.6	1.5	-1.2	0.1	0.6
Mean Putamen Volume	0.4	0.4	0.7	-0.2	-0.8	0.8
Fasting Glucose	0.4	0.5	0.9	-0.3	-1.0	0.6
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.4	-0.4	-0.1	1.2
Chronic bronchitis/emphysema (father)	0.4	0.5	0.6	0.7	0.6	-0.8
Noisy workplace	0.4	0.4	0.7	0.2	0.9	-0.8
Leg fat percentage (right)	0.4	1.3	2.8	0.9	0.5	-1.7
Comparative body size at age 10	0.4	1.1	2.8	0.6	0.3	-1.7
Whole body fat mass	0.4	1.5	3.1	-1.2	-1.7	-0.2
Leg pain on walking	0.4	0.5	1.4	1.2	0.4	-0.1
Arm fat percentage (left)	0.4	1.5	3.4	-1.0	-1.8	0.3
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.5	-0.7	-0.7	0.7
Medication: Aspirin	0.4	0.5	1.5	0.4	1.2	0.0
Ever taken oral contraceptive pill	0.4	0.5	0.9	-0.7	-0.9	-0.2
Medication: Metformin	0.3	0.4	0.8	-0.3	-0.9	0.4
Diabetes (mother)	0.3	0.4	0.9	0.4	0.2	-0.9
Townsend deprivation index at recruitment	0.3	0.5	1.1	0.6	0.1	-1.0
Age when periods started (menarche)	0.3	0.7	1.2	-0.9	-1.1	-0.0
Mouth/teeth dental problems	0.3	0.4	1.2	1.1	0.3	0.2
Allergy	0.3	0.7	0.9	0.9	1.0	-0.7
Pulse rate	0.3	0.4	0.9	1.0	0.6	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.5	0.7	0.6	-0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	1.2	-0.3	0.3	-1.1
Medication: Lansoprazole	0.3	0.3	0.8	-0.9	0.2	0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.7	-0.8	-0.5	0.8
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.7	-0.8	-0.7	0.2
Qualifications: College or University degree	0.3	1.0	2.1	1.4	0.9	-0.5
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.6	-0.8	-0.5	-0.3
Emphysema/chronic bronchitis	0.3	0.3	0.9	-0.2	0.3	-0.9
Number of full sisters	0.3	0.4	1.0	0.2	0.2	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.5	0.4	0.6	-0.7
Eye problems/disorders: Cataract	0.3	0.3	0.5	-0.7	0.2	-0.7
Hearing aid user	0.3	0.3	0.5	0.3	0.7	-0.6
Commuting to job workplace: Public transport	0.3	0.4	0.7	0.4	0.8	-0.6
Leg fat mass (left)	0.3	1.1	2.2	-1.0	-1.5	-0.3
Bipolar Disorder (2018)	0.2	0.4	0.9	0.2	1.0	0.3
Alzheimer’s Disease (including proxy)	0.2	0.2	0.3	-0.6	-0.5	0.5
Prostate Cancer	0.2	0.3	0.8	-0.9	-0.2	0.2
Triglycerides	0.2	0.3	0.8	0.1	-0.4	0.9
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.4	0.5	0.6	-0.5
Blood Eosinophil Count	0.2	1.8	3.1	-1.8	-0.8	1.3
Blood Red Count	0.2	1.6	4.4	-0.1	2.1	0.7
Height	0.2	3.0	6.7	-2.6	-1.5	-0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.7	0.7	-0.2	-0.8
Tanning	0.2	2.5	4.7	1.2	1.2	-2.2
Hand grip strength (left)	0.2	0.5	1.3	0.6	0.1	-1.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.6	0.5	0.8	0.1
Waist circumference	0.2	0.6	1.2	-0.6	-1.1	-0.5
Number of incorrect matches in round	0.2	0.3	0.9	0.3	0.9	0.1
Alcohol usually taken with meals	0.2	0.3	0.4	-0.4	-0.4	0.6
Hearing difficulty/problems with background noise	0.2	0.4	0.9	0.2	1.0	-0.4
Exposure to tobacco smoke at home	0.2	0.2	0.4	-0.6	-0.5	-0.2
Headache pain in last month	0.2	0.4	0.5	-0.7	-0.6	0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.4	0.3	-0.7	-0.6
Pulse wave peak to peak time	0.2	0.2	0.4	-0.3	-0.6	-0.5
Medication: Blood pressure	0.2	0.4	0.8	-0.3	0.9	0.5
Mean time to correctly identify matches	0.2	0.3	0.8	0.4	0.9	-0.1
Leg fat mass (right)	0.2	0.8	1.6	-0.6	-1.3	-0.6
Medication: Aspirin	0.2	0.2	0.4	-0.1	0.6	0.5
Supplements: Vitamin C	0.2	0.3	0.6	0.1	-0.8	0.4
Ever had bowel cancer screening	0.2	0.2	0.6	-0.8	0.2	-0.0
Qualifications: nursing, teaching	0.2	0.3	0.4	0.6	0.4	-0.4
Miserableness	0.2	0.4	0.6	-0.2	0.7	-0.8
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.7	-0.8	-0.0	-0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.6	0.8	-0.2	-0.0
Alcohol drinker status: Never	0.2	0.2	0.6	0.1	-0.2	0.8
Age started oral contraceptive pill	0.2	0.2	0.3	-0.6	0.5	-0.4
Myopia	0.2	0.3	0.6	0.3	-0.4	0.8
Depressed Affect (Nagel 2018)	0.1	0.2	0.5	0.3	0.7	-0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.2	-0.4	0.3
Reaction Time	0.1	0.3	0.5	0.6	0.7	0.1
HbA1C	0.1	0.1	0.3	0.1	-0.0	0.5
LDL Cholesterol	0.1	0.1	0.2	-0.5	-0.2	0.2
Neuroticism (2016)	0.1	0.2	0.4	-0.0	0.5	0.6
Ulcerative Colitis	0.1	0.2	0.3	0.6	0.4	-0.0
Blood Platelet Count	0.1	0.8	1.6	-0.1	0.8	-1.3
Hypothyroidism (self reported)	0.1	0.1	0.2	-0.3	-0.5	-0.1
Lung FEV1/FVC ratio	0.1	0.4	1.3	-0.3	-0.1	-1.1
Hearing difficulty/problems: Yes	0.1	0.1	0.3	0.3	0.5	0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.4	-0.3	0.2	0.6
Medication for hormone replacement therapy	0.1	0.1	0.3	-0.1	0.2	-0.5
Trunk fat percentage	0.1	0.5	1.1	-0.5	-1.1	-0.4
Fed-up feelings	0.1	0.2	0.6	-0.8	-0.1	-0.1
Taking other prescription medications	0.1	0.1	0.2	-0.2	-0.1	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.4	-0.6	-0.7	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	-0.1	-0.5	0.4
Medication: Levothyroxine sodium	0.1	0.1	0.2	0.1	0.5	-0.2
Pain all over the body in last month	0.1	0.1	0.1	-0.4	0.3	-0.3
Diabetes (self-reported)	0.1	0.1	0.3	-0.0	-0.2	-0.6
Father’s age at death	0.1	0.1	0.2	-0.2	-0.4	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.1	0.4	0.1	-0.3
Happiness	0.1	0.1	0.3	0.0	0.2	-0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	-0.0	-0.4	0.6
Asthma	0.1	0.1	0.3	0.5	-0.1	-0.3
Medication: Cholesterol lowering	0.1	0.1	0.3	-0.4	0.2	0.5
Depression (self-reported)	0.1	0.1	0.1	-0.4	0.2	0.1
Prospective memory result	0.1	0.1	0.3	-0.6	-0.1	0.2
Pulse wave Arterial Stiffness index	0.1	0.2	0.3	0.0	0.4	0.6
Standing height	0.1	1.1	2.2	-1.5	-1.0	-0.2
Breastfed as a baby	0.1	0.1	0.4	-0.0	0.6	0.3
Blood clot in the leg (DVT)	0.1	0.1	0.3	0.5	-0.2	0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.3	-0.5	-0.1	0.2
Body fat percentage	0.1	0.3	0.6	-0.1	-0.5	-0.8
Number of children fathered	0.1	0.1	0.2	0.0	0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	-0.1	-0.5	0.3
Knee pain experienced in last month	0.1	0.2	0.4	0.6	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.5	-0.1	-0.7	0.1
Average weekly red wine intake	0.1	0.1	0.2	0.3	0.0	0.4
Diabetes diagnosed by doctor	0.1	0.2	0.5	0.0	-0.1	-0.7
Asthma (self-reported)	0.1	0.2	0.4	0.7	-0.1	-0.3
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	-0.2	0.6	0.3
High cholesterol (Self-reported)	0.1	0.3	0.7	-0.0	0.8	-0.3
Leg fat percentage (left)	0.1	0.4	1.2	0.1	0.0	-1.1
Number of operations (self-reported)	0.1	0.2	0.5	-0.7	-0.3	0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.3	0.0	-0.4	0.6
Irritable Bowel Disease (IBD)	0.0	0.1	0.1	0.1	-0.2	0.3
Ovarian Cancer	0.0	0.1	0.1	0.3	-0.2	-0.1
Hair Pigment	0.0	1.0	1.5	0.8	1.2	-0.9
Multivitamins +/- minerals	0.0	0.0	0.0	0.2	-0.0	0.2
Sitting height	0.0	0.1	0.3	-0.3	0.1	0.5
Had other major operations	0.0	0.0	0.0	-0.1	-0.0	0.2
Medication: Simvastatin	0.0	0.1	0.1	-0.1	0.4	-0.1
Gout (self-reported)	0.0	0.0	0.1	-0.2	0.2	0.0
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	-0.1	-0.1	-0.0
Medication: Omeprazole	0.0	0.0	0.1	0.0	0.3	0.1
Loneliness, isolation	0.0	0.0	0.0	-0.1	-0.1	0.0
Medication: Gliclazide	0.0	0.0	0.0	0.1	-0.0	0.2
Guilty feelings	0.0	0.1	0.1	-0.3	0.3	-0.2
Wears glasses or contact lenses	0.0	0.1	0.1	-0.3	0.2	0.2
Mother’s age at death	0.0	0.0	0.1	-0.2	-0.2	0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	-0.2	0.1	0.3
Alcohol drinker status: Previous	0.0	0.0	0.1	-0.3	0.2	-0.1

Hub : Genes

USMG5

Models

Trait associations