TWAS hub - UGT3A2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0390	0.0210	9.7e-03	0.004	0.009	-0.003	NA	0.000	1.3e-01	4.9e-02	6.5e-01	NA	3.4e-01
2	TCGA	Breast Invasive Carcinoma	0.0588	0.0209	2.4e-09	0.024	0.046	0.045	NA	0.042	7.4e-06	9.7e-10	1.2e-09	NA	4.0e-09
3	TCGA	Colon Adenocarcinoma	0.1060	0.0520	5.5e-04	0.075	0.027	0.009	NA	0.038	3.8e-05	1.0e-02	8.8e-02	NA	2.9e-03
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0589	0.0266	1.6e-04	0.050	0.033	0.027	NA	0.033	2.7e-06	1.3e-04	4.2e-04	NA	1.2e-04
5	TCGA	Lung Adenocarcinoma	0.1140	0.0353	9.1e-12	0.092	0.107	0.101	NA	0.111	7.3e-11	1.7e-12	7.0e-12	NA	6.0e-13
6	TCGA	Lung Squamous Cell Carcinoma	0.0483	0.0276	2.8e-03	0.031	0.039	0.020	NA	0.023	1.8e-04	2.8e-05	2.2e-03	NA	1.1e-03
7	TCGA	Ovarian Serous Cystadenocarcinoma	0.0430	0.0230	5.8e-03	0.046	0.021	0.034	NA	0.034	4.5e-04	1.4e-02	2.2e-03	NA	2.3e-03
8	TCGA	Pancreatic Adenocarcinoma	0.1740	0.0680	1.3e-04	0.058	0.081	0.066	NA	0.068	1.9e-03	2.8e-04	9.7e-04	NA	8.3e-04
9	TCGA	Prostate Adenocarcinoma	0.0606	0.0265	2.3e-05	0.043	0.046	0.046	NA	0.044	2.7e-05	1.2e-05	1.4e-05	NA	1.8e-05
10	TCGA	Rectum Adenocarcinoma	0.2910	0.0880	1.1e-05	0.260	0.230	0.238	NA	0.255	8.1e-07	4.0e-06	2.7e-06	NA	1.0e-06
11	TCGA	Stomach Adenocarcinoma	0.0680	0.0310	8.0e-04	0.042	0.013	0.002	NA	0.021	4.8e-04	3.8e-02	2.2e-01	NA	1.0e-02
12	TCGA	Thyroid Carcinoma	0.0540	0.0290	5.3e-03	-0.001	0.021	0.012	NA	0.009	4.5e-01	3.4e-03	2.0e-02	NA	3.9e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Hayfever, allergic rhinitis or eczema	13.1	28.5	57.8	7.6	6.1	5.3	4.8	5.1	5.4	3.7	4.1	3.7	5.7	4.8	6.4
Allergy or Eczema	11.2	29.5	65.4	8.1	6.4	5.4	4.4	5.2	5.4	4.0	4.0	3.8	5.5	4.8	6.5
Hayfever/allergic rhinitis (self-reported)	9.5	12.6	21.8	4.7	4.6	3.7	3.0	3.4	3.3	2.4	4.0	2.3	3.8	3.3	3.3
Allergy	9.1	20.8	44.5	-6.7	-5.4	-4.5	-3.7	-4.4	-4.2	-3.6	-3.8	-3.6	-4.7	-3.9	-5.4
Ever had stillbirth, spontaneous miscarriage or termination	5.4	5.7	9.8	-2.5	-2.6	-2.6	-2.4	-2.7	-3.1	-0.7	-1.7	-0.9	-2.7	-2.9	-2.3
Illnesses of father: None of the above (group 1)	5.1	6.3	10.1	2.2	2.7	2.9	2.4	3.2	2.0	1.3	3.0	1.5	3.0	2.9	2.3
Birth weight	3.5	7.7	20.1	-2.5	-3.7	-2.6	-2.4	-2.5	-1.2	-2.6	-4.5	-3.1	-2.2	-2.4	-2.2
Alcohol drinker status: Never	3.4	4.1	8.3	1.7	1.5	2.4	1.6	2.4	2.9	-1.4	0.1	-1.2	2.4	2.4	2.5
Ovarian Cancer	3.1	4.1	7.8	1.8	2.4	2.2	2.0	2.1	1.8	1.0	2.8	1.3	2.3	2.0	2.1
Mouth/teeth dental problems	3.1	4.7	7.0	-2.4	-2.4	-2.4	-2.7	-2.4	-2.1	-1.1	-2.2	-1.1	-2.6	-2.3	-1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.9	3.4	13.5	-1.7	-1.7	-0.5	-0.5	-0.2	-0.0	-3.5	-3.0	-3.7	-0.3	-0.2	0.1
Alzheimer’s Disease (in mother)	2.7	3.2	5.1	1.8	1.7	1.6	1.5	2.2	0.9	1.4	2.1	2.3	1.7	1.8	2.0
Impedance of leg (left)	2.5	12.1	21.9	2.6	3.2	4.4	4.4	4.3	3.8	0.4	2.4	-0.2	4.7	4.3	3.2
Happiness	2.5	3.0	4.9	2.0	2.2	2.0	1.8	2.2	0.6	1.5	1.5	1.3	1.9	1.6	1.4
Ulcerative Colitis	2.3	3.3	7.7	-2.2	-2.2	-1.3	-1.2	-1.3	-1.6	-1.8	-2.3	-2.8	-1.1	-1.5	-1.7
Number of children fathered	2.3	2.6	3.6	-1.9	-1.8	-1.8	-1.4	-1.9	-0.8	-1.5	-1.4	-1.7	-1.4	-1.7	-1.9
Trunk fat-free mass	2.2	12.7	20.4	-3.6	-3.6	-4.2	-4.3	-4.3	-3.7	-1.8	-2.3	-1.0	-4.5	-4.1	-3.5
Trunk predicted mass	2.2	12.4	20.1	-3.5	-3.5	-4.2	-4.2	-4.2	-3.6	-1.7	-2.2	-1.0	-4.5	-4.1	-3.5
Ulcerative Colitis (UC)	2.1	3.9	7.1	-2.1	-2.4	-1.5	-1.7	-1.7	-1.5	-1.6	-2.5	-2.7	-1.6	-1.6	-2.2
Whole body fat-free mass	2.1	12.1	19.4	-3.5	-3.7	-4.2	-4.2	-4.2	-3.5	-1.5	-2.3	-0.8	-4.4	-4.0	-3.4
Unable to work because of sickness or disability	2.1	2.7	5.8	1.8	1.6	1.6	1.3	1.5	1.2	1.0	1.8	2.1	1.2	1.6	2.4
Had other major operations	2.0	2.5	5.4	0.7	1.0	1.9	1.6	2.2	1.8	-0.7	1.1	-0.2	2.1	2.3	1.5
Illnesses of father: Heart disease	2.0	2.8	4.8	-1.7	-1.9	-2.1	-1.4	-2.2	-1.3	-0.8	-1.7	-0.9	-1.7	-2.1	-1.6
Whole body water mass	2.0	11.7	19.1	-3.4	-3.6	-4.1	-4.1	-4.1	-3.5	-1.4	-2.1	-0.7	-4.4	-4.0	-3.3
Crohns Disease (2012)	1.9	3.0	5.7	1.0	1.1	2.2	2.2	2.4	1.5	0.7	1.6	0.9	2.2	2.3	1.5
Impedance of leg (right)	1.9	9.4	17.4	2.2	2.9	4.0	4.0	3.9	3.2	0.6	2.0	-0.2	4.2	3.9	2.5
Leg fat-free mass (left)	1.9	10.3	16.3	-3.0	-3.7	-3.9	-3.8	-3.9	-3.2	-0.9	-2.2	-0.4	-4.0	-3.7	-3.1
Leg predicted mass (left)	1.9	10.3	16.4	-3.0	-3.7	-3.9	-3.9	-3.9	-3.2	-0.9	-2.2	-0.4	-4.0	-3.8	-3.1
Leg pain on walking	1.9	2.4	4.8	-0.9	-1.1	-2.0	-1.8	-1.4	-1.8	-0.8	-2.2	-0.8	-2.0	-2.0	-1.0
Basal metabolic rate	1.9	10.3	17.0	-3.1	-3.6	-3.9	-3.8	-4.0	-3.2	-1.1	-2.1	-0.4	-4.1	-3.8	-3.0
Mouth/teeth dental problems: Bleeding gums	1.8	2.4	4.5	2.1	1.6	1.3	1.2	1.2	1.3	1.5	1.6	1.9	1.1	1.4	1.9
Shortness of breath walking on level ground	1.8	2.2	3.9	-1.0	-1.0	-1.8	-1.7	-1.8	-1.4	0.8	-1.2	-0.2	-1.8	-1.8	-2.0
Leg fat-free mass (right)	1.8	9.6	15.4	-2.9	-3.5	-3.8	-3.7	-3.9	-3.0	-1.1	-2.0	-0.4	-3.9	-3.6	-2.8
Medication: Blood pressure	1.8	3.4	5.2	-2.3	-2.2	-1.8	-1.7	-1.9	-1.9	-1.6	-1.6	-1.2	-1.9	-1.9	-1.8
Alzheimer’s Disease (in father)	1.7	1.9	5.0	-1.3	-1.6	-1.1	-0.9	-1.8	-0.0	-2.2	-1.6	-1.8	-1.0	-1.1	-0.3
Body Mass Index (BMI) (2010)	1.7	2.3	5.3	0.3	0.1	2.0	2.0	1.8	2.1	-1.0	0.1	-0.7	1.7	2.3	1.5
Blood Eosinophil Count	1.7	13.2	25.6	5.1	4.1	3.2	2.1	3.6	1.6	3.5	4.4	3.7	3.0	3.2	4.5
Ever had hysterectomy (womb removed)	1.7	1.9	8.5	-1.7	-0.6	0.0	0.4	-0.2	0.0	-2.7	-1.5	-2.9	0.1	0.1	-1.2
Medication: Aspirin	1.7	2.2	7.3	1.2	1.8	0.6	0.8	0.4	-0.1	2.3	2.7	2.6	0.3	0.8	0.5
Leg predicted mass (right)	1.7	9.0	14.6	-2.9	-3.4	-3.6	-3.6	-3.7	-2.9	-1.1	-1.9	-0.4	-3.8	-3.5	-2.8
Heart disease (siblings)	1.7	2.1	4.5	-1.4	-1.2	-1.6	-1.2	-1.5	-2.1	0.6	-0.9	0.3	-1.8	-1.6	-1.9
Arm predicted mass (left)	1.7	8.4	14.2	-3.0	-3.1	-3.5	-3.5	-3.6	-3.0	-1.0	-1.4	-0.2	-3.8	-3.3	-2.8
Vitamin and mineral supplements	1.6	2.2	5.1	1.8	0.3	1.7	1.0	1.6	2.3	1.0	-0.0	0.8	1.4	1.7	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	3.3	1.5	1.7	1.7	1.8	1.6	1.6	0.3	1.0	0.0	1.7	1.6	1.4
Pain all over the body in last month	1.6	1.7	3.4	-1.3	-1.5	-1.3	-1.8	-0.9	-1.8	-1.5	-1.0	-0.5	-1.5	-1.2	0.4
Birth weight of first child	1.6	2.9	6.3	-0.8	-0.8	-1.8	-2.2	-1.7	-0.7	-1.7	-2.5	-2.4	-1.8	-1.8	-1.2
Hypothyroidism/myxoedema (self-reported)	1.6	3.0	4.4	2.1	1.7	1.8	1.4	1.6	1.6	2.0	2.0	1.7	1.7	1.8	1.4
Arm fat-free mass (right)	1.6	8.0	13.0	-2.9	-3.1	-3.4	-3.4	-3.5	-2.9	-1.2	-1.5	-0.5	-3.6	-3.2	-2.7
Family relationship satisfaction	1.6	2.0	5.8	1.6	2.4	1.7	1.4	1.8	0.9	0.7	1.0	0.3	1.4	1.5	0.4
Impedance of whole body	1.6	8.1	15.7	2.2	2.6	3.6	3.7	3.6	3.2	0.4	1.3	-0.7	4.0	3.5	2.4
Qualifications: CSEs or equivalent	1.5	1.9	7.0	-2.1	-2.1	-0.6	-0.6	-0.6	-0.4	-2.6	-1.3	-2.0	-0.4	-0.5	-0.3
Serious illness, injury or assault to yourself	1.5	1.8	4.5	1.5	2.1	1.3	1.7	1.3	0.4	1.4	1.1	1.4	1.0	1.3	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	5.6	2.4	1.8	1.4	0.9	1.4	1.9	1.0	0.4	0.6	1.1	1.4	1.4
Arm predicted mass (right)	1.5	7.6	12.5	-2.8	-3.0	-3.3	-3.3	-3.5	-2.7	-1.0	-1.4	-0.5	-3.5	-3.2	-2.8
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	5.6	2.3	1.6	1.3	1.2	1.5	1.6	0.9	1.4	1.2	1.6	1.1	2.4
Osteoporosis (self-reported)	1.5	1.9	3.2	-1.3	-1.7	-1.6	-1.0	-1.7	-1.8	0.5	-0.7	0.1	-1.5	-1.5	-1.8
Risk taking	1.5	2.1	5.9	0.8	1.6	1.8	2.4	1.8	1.1	0.4	1.2	0.3	2.0	1.5	0.9
Alcohol drinker status: Previous	1.5	1.8	3.0	1.0	1.7	1.4	1.7	1.5	0.2	0.7	1.6	1.1	1.2	1.6	1.1
Crohns Disease (2017)	1.4	3.0	4.4	2.1	1.5	1.9	1.8	2.0	1.6	1.6	1.2	1.4	1.9	2.0	1.6
Major Depression (MDD)	1.4	1.7	6.5	-1.4	-1.1	-1.2	-1.8	-0.5	-2.5	-0.9	-0.6	-0.8	-1.3	-1.2	-1.0
Height	1.4	27.1	42.1	-6.5	-5.3	-5.0	-4.1	-4.9	-3.9	-5.5	-5.2	-6.4	-4.7	-4.5	-5.8
Average weekly fortified wine intake	1.4	1.7	4.7	-1.7	-1.2	-1.0	-0.3	-1.3	-0.6	-2.2	-1.6	-1.7	-0.8	-1.0	-0.8
Weight	1.4	6.7	11.9	-2.0	-3.0	-3.3	-3.1	-3.5	-2.3	0.2	-1.8	0.7	-3.4	-3.2	-2.0
Breastfed as a baby	1.4	1.8	3.0	-1.4	-1.1	-1.7	-1.6	-1.4	-1.0	-1.3	-1.2	-0.7	-1.5	-1.6	-0.9
High blood pressure (siblings)	1.4	2.0	4.3	-1.4	-0.6	-1.5	-2.1	-0.8	-1.6	-2.0	-1.0	-1.5	-1.7	-1.1	-0.5
Average weekly beer plus cider intake	1.4	2.1	4.7	1.4	0.8	1.8	1.3	1.9	2.2	0.0	0.2	-0.3	2.0	1.7	1.4
Waist circumference	1.3	4.7	8.6	-1.1	-2.3	-2.9	-2.8	-2.9	-1.8	0.6	-1.7	0.9	-2.9	-2.9	-1.2
Qualifications: A levels/AS levels or equivalent	1.3	2.8	9.9	2.2	2.2	1.0	1.3	1.0	0.7	3.2	1.7	2.3	0.8	1.0	0.1
Medication: Ventolin 100micrograms inhaler	1.3	1.7	4.5	2.1	1.4	1.1	0.5	0.9	1.7	1.0	0.8	1.2	1.2	0.8	1.7
Breast cancer (self-reported)	1.3	1.5	4.4	1.1	0.7	1.6	0.7	1.7	0.7	0.2	1.2	0.4	1.2	1.7	2.1
Mother’s age at death	1.3	1.7	3.6	-1.5	-0.7	-1.5	-1.2	-1.7	-1.9	-0.2	-0.1	-0.3	-1.7	-1.3	-1.6
Arm fat-free mass (left)	1.3	6.8	11.8	-2.7	-2.8	-3.2	-3.2	-3.2	-2.7	-1.0	-1.1	-0.2	-3.4	-3.0	-2.4
Ever depressed for a whole week	1.3	1.5	4.7	1.1	2.2	1.1	1.4	1.2	-0.0	1.4	1.8	1.1	1.2	0.7	-0.2
Medication: Co-codamol	1.2	1.4	4.1	1.9	1.3	1.0	0.5	0.8	2.0	-0.3	-0.1	-0.1	0.7	1.2	1.9
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	6.2	-1.4	-0.8	0.1	0.7	-0.1	0.3	-2.5	-1.3	-2.4	0.3	0.2	-0.4
Exposure to tobacco smoke at home	1.2	1.4	5.1	1.1	-0.2	-1.1	-0.9	-1.2	-0.6	1.6	-0.2	2.3	-1.1	-1.3	0.7
Medication: Allopurinol	1.2	1.6	5.8	1.2	0.1	-1.2	-0.8	-1.4	-0.3	2.4	0.1	2.3	-1.1	-1.4	-0.0
Fractured/broken bones in last 5 years	1.2	1.6	2.8	-1.2	-1.4	-1.6	-1.2	-1.4	-0.4	-0.8	-1.7	-1.1	-1.5	-1.1	-1.1
Type 2 Diabetes (T2D) (2012)	1.1	1.3	2.5	1.3	1.5	1.3	1.6	1.0	1.2	0.4	0.7	0.7	1.2	1.2	0.9
Medication for hormone replacement therapy	1.1	1.2	2.8	0.4	1.0	1.3	1.7	1.4	0.3	-0.4	1.1	0.3	1.5	1.3	1.1
Taking other prescription medications	1.1	1.7	2.6	1.5	1.6	1.2	1.3	1.1	0.8	1.6	1.6	1.5	1.2	1.0	0.9
Supplements: Glucosamine	1.1	1.4	2.5	-0.3	-0.6	-1.6	-1.2	-1.6	-1.1	1.2	-0.6	0.6	-1.4	-1.6	-1.2
Fluid intelligence score	1.1	2.3	4.8	1.3	1.3	1.8	1.7	2.2	1.9	-0.5	0.0	-0.7	2.0	2.1	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	3.6	1.6	1.9	0.7	1.6	0.6	0.7	1.5	1.7	1.6	0.9	0.7	0.8
Medication: Seretide 50 evohaler	1.1	1.2	5.1	1.5	1.1	0.9	0.3	1.1	-0.1	2.3	1.1	1.3	0.8	0.6	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.6	-1.6	-1.2	-0.6	-0.6	-0.3	-0.6	-1.7	-1.4	-1.9	-0.7	-0.4	-1.1
Neuroticism (2016)	1.0	1.5	3.3	-1.5	-1.8	-1.2	-1.0	-1.1	-1.3	-0.6	-1.6	-0.5	-1.4	-1.2	-0.9
Number of treatments/medications taken	1.0	1.8	3.8	1.0	1.9	1.4	1.9	1.2	0.4	1.2	1.9	1.3	1.3	1.2	0.6
Nervous feelings	1.0	1.9	4.4	-2.0	-1.5	-1.0	-0.2	-1.2	-0.6	-2.1	-1.8	-1.6	-1.0	-0.7	-1.4
Hip circumference	1.0	4.3	8.6	-1.3	-2.4	-2.7	-2.2	-2.9	-1.4	0.6	-1.7	0.9	-2.7	-2.6	-1.7
Pulse rate	1.0	1.6	3.5	-1.0	-1.4	-1.7	-1.4	-1.4	-1.0	-0.4	-1.9	-0.6	-1.4	-1.5	-0.6
Asthma	1.0	1.9	4.4	2.1	1.8	1.0	-0.1	1.2	0.9	1.1	1.7	1.3	1.1	0.8	2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	3.5	-0.9	0.1	-1.2	-0.7	-1.5	-1.1	-0.2	-0.8	-0.6	-1.3	-1.4	-1.9
Mean time to correctly identify matches	1.0	1.9	3.6	0.3	1.3	1.8	1.5	1.9	1.1	-0.8	1.2	-1.1	1.7	1.9	1.2
Heart disease (mother)	1.0	1.2	2.5	0.3	0.5	1.3	1.5	1.6	0.1	0.8	1.3	1.0	1.3	1.4	0.3
Smoking status: Current	1.0	1.6	3.8	-0.8	-0.8	-1.6	-1.4	-1.5	-1.5	0.5	-0.6	-0.0	-1.2	-1.7	-1.9
Guilty feelings	1.0	1.5	3.2	0.6	1.4	1.6	1.8	1.8	0.4	0.4	1.2	0.4	1.5	1.6	0.4
Cholesterol lowering medication	1.0	1.5	3.2	-0.5	-1.0	-1.6	-1.8	-1.4	-1.3	0.8	-0.7	0.8	-1.7	-1.4	-0.9
Breast Cancer	0.9	2.2	4.7	2.2	1.6	1.1	1.3	1.2	2.0	1.4	0.9	1.4	1.5	1.0	1.8
Age when periods started (menarche)	0.9	2.2	4.2	-0.4	0.5	1.7	1.6	1.8	0.8	-2.0	0.7	-2.0	1.8	1.9	0.7
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	2.3	0.1	0.7	1.0	1.0	0.9	0.9	-1.5	0.1	-1.1	1.2	0.9	1.1
Diabetes (self-reported)	0.9	1.4	2.9	-0.5	-0.7	-1.5	-1.6	-1.2	-1.7	1.0	0.1	1.4	-1.4	-1.4	-0.2
Number of live births	0.9	1.3	4.0	-1.6	-0.8	-1.1	-0.7	-1.4	-1.0	-0.8	-0.2	-0.9	-1.0	-1.1	-2.0
Impedance of arm (left)	0.9	3.9	8.1	1.7	1.7	2.5	2.6	2.6	2.2	0.3	0.2	-0.7	2.8	2.4	1.7
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	4.9	1.8	1.9	0.6	0.3	1.1	0.5	2.2	1.2	1.5	0.5	0.6	-0.2
Medication: Amlodipine	0.9	1.3	4.3	-1.5	-0.6	-0.2	-0.5	-0.2	-0.3	-1.5	-1.5	-2.1	-0.8	-0.1	-1.7
Comparative height size at age 10	0.9	5.2	9.1	-2.0	-2.0	-2.4	-2.3	-2.5	-1.3	-0.8	-2.9	-2.2	-2.7	-2.2	-3.0
Average weekly red wine intake	0.9	1.3	3.4	1.4	1.9	1.0	1.4	0.8	1.3	0.8	0.8	1.3	1.1	0.7	0.7
Vascular/heart problems diagnosed by doctor	0.9	2.5	4.9	2.0	1.7	1.5	0.9	1.4	2.2	0.5	1.3	0.2	1.9	1.5	2.1
Medication: Omeprazole (e.g. Zanprol)	0.9	1.0	2.4	0.2	0.4	0.9	1.5	1.1	1.0	-1.3	-0.1	-0.9	1.3	1.1	1.3
Hypothyroidism (self reported)	0.8	1.8	2.5	1.4	1.0	1.5	1.2	1.5	1.4	1.3	1.3	1.0	1.6	1.5	1.2
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.1	0.3	0.7	1.3	1.4	1.3	0.6	-0.6	0.9	-0.4	1.3	1.3	1.1
Severe depression (siblings)	0.8	0.9	4.8	1.1	-0.2	-0.3	-0.7	-0.0	-0.0	0.3	-0.1	1.9	-0.5	-0.2	2.2
Medication: Levothyroxine sodium	0.8	1.3	4.3	1.6	1.3	0.8	0.6	0.5	0.7	2.1	1.2	1.6	0.6	0.7	0.5
Number of incorrect matches in round	0.8	1.3	2.8	-1.3	-0.7	-1.2	-0.9	-1.2	-1.7	-1.1	-0.5	-1.4	-1.1	-1.1	-1.1
Impedance of arm (right)	0.8	4.0	7.9	1.6	2.0	2.6	2.5	2.7	1.9	0.6	0.7	-0.7	2.8	2.5	1.2
Alcohol intake versus 10 years previously	0.8	1.2	2.2	-0.4	-0.5	-1.5	-1.3	-1.4	-0.9	0.4	-1.1	-0.2	-1.3	-1.5	-1.4
Prospective memory result	0.8	1.0	3.1	0.2	0.7	1.1	1.4	1.1	0.7	-0.1	1.1	0.7	1.4	0.9	1.8
Standing height	0.8	8.1	13.8	-3.7	-3.0	-2.7	-2.5	-2.6	-2.5	-2.9	-2.3	-3.1	-2.7	-2.4	-3.4
Emphysema/chronic bronchitis	0.8	0.9	2.2	-0.3	-0.8	-1.0	-1.2	-1.2	-0.7	-0.0	-1.5	-0.2	-1.1	-1.3	-0.5
Supplements: Vitamin C	0.8	1.0	2.1	-1.2	-0.9	-0.9	-0.8	-0.3	-1.4	-1.3	-1.4	-1.1	-0.6	-0.8	-0.6
Hypertension (Self-reported)	0.8	2.4	4.5	-1.7	-1.6	-1.6	-1.0	-1.6	-2.1	-0.1	-1.1	0.4	-1.9	-1.7	-2.1
Mood swings	0.8	1.5	3.6	-0.4	-0.4	1.4	1.2	1.5	1.0	-1.9	-0.3	-1.4	1.3	1.5	1.1
Asthma (self-reported)	0.8	1.7	3.8	2.0	1.6	0.9	-0.2	1.1	0.8	1.1	1.7	1.4	1.0	0.7	1.9
Medication: Aspirin	0.8	1.0	4.0	0.5	1.3	0.3	0.6	0.2	-0.3	1.5	2.0	1.8	0.2	0.4	0.3
Reaction Time	0.7	1.3	2.9	0.4	1.1	1.6	0.9	1.6	1.1	-0.3	1.1	-0.6	1.2	1.7	1.0
Bipolar Disorder (2011)	0.7	0.7	2.9	-0.4	-1.5	-0.8	-0.5	-0.7	-0.4	-0.3	-1.7	-0.2	-0.4	-1.0	0.4
Coronary Artery Disease (CAD)	0.7	0.9	3.2	0.4	0.7	1.8	1.3	1.1	0.5	0.3	0.5	-0.3	1.3	1.2	0.4
Mean Putamen Volume	0.7	0.8	1.8	1.2	0.3	0.7	0.6	0.4	0.9	1.0	0.7	1.3	0.7	0.7	1.3
Lupus	0.7	1.1	2.3	-0.6	-0.9	-1.4	-1.4	-1.0	-1.0	-0.2	-1.5	-0.6	-1.3	-1.2	-0.7
Rheumatoid Arthritis	0.7	0.9	3.9	-1.4	-1.1	0.0	-0.2	0.3	-0.8	-2.0	-0.8	-1.6	-0.1	0.0	0.2
Respiratory disease	0.7	1.7	5.8	2.4	1.7	0.3	-0.9	0.3	0.6	2.1	1.3	1.6	0.2	0.0	1.0
Type 2 Diabetes (T2D) (2018)	0.7	1.2	4.3	0.8	0.7	-0.8	-1.1	-0.8	-1.0	2.1	1.1	1.8	-0.9	-0.8	-0.2
Current tobacco smoking	0.7	1.2	2.8	-0.6	-0.7	-1.4	-1.1	-1.2	-1.2	0.5	-0.7	-0.1	-1.0	-1.5	-1.7
High blood pressure	0.7	2.0	3.5	-1.8	-1.7	-1.4	-0.7	-1.3	-1.9	-0.7	-1.4	-0.2	-1.7	-1.4	-1.9
Body mass index (BMI)	0.7	2.8	5.2	-0.3	-1.8	-2.1	-1.9	-2.3	-1.1	1.5	-0.7	2.2	-2.2	-2.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.3	1.5	1.3	0.7	1.0	0.5	1.0	1.0	0.6	1.5	0.5	0.6	1.4
Illnesses of siblings	0.7	1.0	2.4	0.6	0.1	1.3	1.5	0.7	1.3	0.5	1.0	0.6	1.5	1.0	0.9
Noisy workplace	0.7	0.9	1.9	0.4	-0.5	-1.1	-1.2	-0.9	-1.0	0.8	-0.3	1.4	-1.0	-1.3	0.5
Peak expiratory flow (PEF)	0.7	1.7	3.2	-0.2	-0.4	-1.2	-1.0	-1.2	-1.8	1.8	0.6	1.8	-1.4	-1.2	-1.6
Medication: Paracetamol	0.7	1.2	3.0	1.0	1.4	1.2	1.7	0.7	0.8	0.8	1.3	1.0	1.3	0.9	0.6
Gout (self-reported)	0.7	1.0	2.0	0.3	0.1	-1.4	-1.3	-1.4	-0.4	1.3	0.2	0.9	-1.2	-1.4	-0.7
Medication for pain relief, constipation, heartburn	0.7	1.1	4.9	-0.4	-1.2	-0.9	-1.3	-0.5	-0.1	-0.8	-2.2	-1.5	-0.7	-0.9	-0.5
Neck or shoulder pain in last month	0.7	1.0	5.6	-0.5	0.7	0.1	0.4	-0.0	-0.9	1.3	2.4	1.7	0.1	0.1	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.2	0.5	-0.4	-1.1	-1.4	-1.1	0.4	0.4	-1.3	0.6	-1.5	-0.9	0.2
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.7	-0.3	-0.5	0.6	1.1	0.3	1.2	-1.6	-0.5	-1.3	0.9	0.7	0.4
Loneliness, isolation	0.7	1.0	2.6	0.3	-0.2	1.0	1.0	1.2	0.9	-0.9	-1.0	-1.2	1.0	1.1	1.6
Medication for cholesterol	0.7	1.1	2.8	1.1	1.1	1.1	1.2	1.0	1.7	0.3	0.4	-0.1	1.3	1.1	1.1
Hearing aid user	0.7	0.8	2.7	0.7	0.3	-0.9	-0.8	-1.0	-0.4	1.6	-0.4	0.8	-1.0	-0.9	-1.1
Financial situation satisfaction	0.7	0.9	2.2	1.2	0.8	0.7	0.2	0.9	0.3	1.1	1.0	1.5	0.4	0.6	1.5
Commuting to job workplace: Public transport	0.7	0.9	1.5	0.9	1.0	1.1	0.8	1.2	0.7	1.2	1.0	0.4	1.1	1.1	0.0
Schizophrenia vs Biploar Disorder	0.6	0.8	2.3	0.2	0.3	-0.8	-0.4	-0.8	-1.1	1.5	1.0	1.3	-0.8	-0.7	-0.7
HDL Cholesterol	0.6	1.0	2.8	-0.7	0.2	-1.2	-1.1	-1.1	-1.4	-0.1	0.2	-0.5	-1.0	-1.2	-1.7
Sensitivity / hurt feelings	0.6	1.1	4.2	-1.1	-1.4	-0.6	-0.6	-0.3	-0.9	-1.4	-2.0	-1.2	-0.7	-0.7	-0.4
Hearing difficulty/problems: Yes	0.6	0.9	2.0	1.0	0.9	1.0	0.7	1.1	1.4	-0.3	-1.0	-0.7	0.9	1.0	0.6
Medication: Metformin	0.6	0.8	4.2	-0.0	-0.4	-0.4	-0.3	-0.5	-1.1	1.4	0.6	2.1	-0.7	-0.4	0.5
Relative age voice broke	0.6	0.9	4.9	-1.3	-0.4	0.0	0.1	-0.0	-0.5	-1.5	-0.7	-2.2	0.1	-0.1	-0.9
Hair/balding pattern: Pattern 2	0.6	0.7	1.9	-0.2	-0.4	-1.2	-1.3	-1.2	-0.7	0.4	-0.2	0.4	-1.4	-1.2	-0.2
Financial difficulties in last 2 years	0.6	0.8	1.7	0.1	-0.0	-0.9	-1.0	-0.8	-1.3	1.0	0.5	1.3	-1.1	-1.0	-0.3
Hair/balding pattern: Pattern 3	0.6	0.8	3.4	-0.0	-0.1	0.8	-0.0	1.0	0.9	-1.8	-0.5	-1.4	0.7	0.7	1.1
Illnesses of mother	0.6	0.8	2.0	0.2	-0.8	-1.1	-1.4	-1.3	0.1	-0.3	-1.1	-0.3	-0.8	-1.2	0.4
Arm fat mass (right)	0.6	2.7	5.2	-0.6	-1.9	-2.0	-1.9	-2.3	-1.1	1.0	-0.9	1.5	-2.2	-2.0	-0.8
Length of working week for main job	0.6	0.7	4.0	0.8	0.2	0.6	0.9	0.3	0.2	2.0	0.6	1.3	0.7	0.4	0.1
Comparative body size at age 10	0.6	1.7	3.8	0.4	0.1	-1.4	-1.8	-1.4	-1.1	2.0	0.7	1.5	-1.6	-1.4	-1.0
Medication: Omeprazole	0.6	0.7	2.4	-0.5	-0.1	0.4	1.3	0.4	0.9	-1.5	-0.3	-1.2	1.0	0.5	0.5
Long-standing illness, disability or infirmity	0.6	0.9	4.0	1.4	0.5	-0.3	-0.3	-0.4	0.1	1.6	0.4	2.0	-0.4	-0.6	1.1
Diabetes diagnosed by doctor	0.6	1.0	3.1	0.4	-0.1	-1.0	-1.2	-0.7	-1.1	1.7	0.2	1.8	-1.0	-0.9	0.2
Mineral and other dietary supplements	0.6	0.9	3.9	0.7	0.3	0.9	0.4	0.7	1.2	-0.4	0.9	0.6	0.8	0.9	2.0
Osteoarthritis (self-reported)	0.6	0.7	2.1	0.2	0.1	-1.0	-0.9	-1.0	-1.4	0.3	0.1	0.9	-1.2	-1.2	0.0
Arm fat mass (left)	0.6	2.4	4.6	-0.4	-1.8	-1.9	-1.9	-2.1	-1.0	1.0	-1.1	1.4	-2.0	-1.9	-0.6
Medication: Bendroflumethiazide	0.6	0.9	2.5	-1.0	-1.4	-0.7	-0.9	-0.6	-0.3	-1.1	-1.6	-0.8	-0.9	-0.6	-0.5
Ever smoked	0.6	1.0	3.5	0.5	1.1	-0.1	0.2	-0.0	-0.5	1.9	1.7	1.2	0.2	-0.2	-1.4
Supplements: Calcium	0.6	0.7	2.5	0.5	1.2	0.3	0.6	0.6	-0.0	1.5	0.8	0.3	0.5	0.5	-1.6
Schizophrenia (2018)	0.5	1.1	2.8	-0.7	-0.3	-1.3	-0.6	-1.6	-1.2	0.2	-0.4	-0.7	-1.1	-1.2	-1.7
Worry (Nagel 2018)	0.5	1.0	2.5	-1.3	-1.0	-0.8	-0.4	-0.8	-1.0	-0.4	-1.2	-0.8	-0.8	-0.7	-1.6
Verbal and Numeric Reasoning (VNR)	0.5	1.3	2.8	1.2	0.9	1.4	1.1	1.4	1.7	-0.1	0.3	-0.1	1.4	1.5	1.0
Average weekly spirits intake	0.5	0.6	2.1	-0.5	0.3	0.5	1.4	0.1	0.3	0.5	1.5	0.2	0.8	0.7	-1.0
Angina	0.5	0.6	2.3	-0.0	0.8	-0.1	-0.0	0.3	-1.4	1.5	1.2	1.0	-0.3	-0.1	-0.3
Stomach or abdominal pain in last month	0.5	0.6	1.8	0.8	0.8	0.9	1.3	0.4	0.8	0.1	0.3	0.8	0.7	0.8	1.2
Heart attack	0.5	0.6	1.4	-1.2	-0.6	-0.7	-0.8	-0.7	-0.7	-0.8	-0.5	-1.1	-0.9	-0.7	-0.8
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.2	0.9	0.7	0.7	0.8	0.3	1.1	0.6	0.5	1.1	0.5	0.6	1.0
Worry too long after embarrassment	0.5	0.9	2.8	-0.7	-0.5	-0.7	-1.2	-0.4	-1.7	0.7	-0.4	-0.1	-1.1	-0.7	-1.6
Wheeze or whistling in the chest in last year	0.5	0.8	3.3	1.5	1.8	0.2	-0.6	0.1	-0.2	1.2	1.3	1.0	-0.2	-0.0	0.2
Eye problems/disorders: None of the above	0.5	0.6	1.5	-0.8	-1.1	-0.9	-1.2	-0.6	-0.6	-1.0	-0.2	0.1	-0.6	-0.5	0.7
Angina (self-reported)	0.5	0.7	2.5	-0.0	0.7	-0.1	0.0	0.3	-1.4	1.6	1.3	1.0	-0.2	-0.1	-0.4
Medication: Ibuprofen	0.5	0.6	3.2	-0.2	0.3	0.8	0.5	0.7	-0.1	0.6	1.8	0.8	0.4	0.9	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.7	-1.0	-0.7	-0.5	-1.0	-0.3	-1.6	-0.3	0.3	0.1	-0.5	-0.6	-0.5
Commuting to job workplace: Walk	0.5	0.5	0.9	-0.8	-0.5	-0.8	-0.8	-1.0	-0.6	-0.4	-0.7	-0.5	-0.7	-0.9	-0.8
Eye problems/disorders: Cataract	0.5	0.6	2.8	-0.7	-0.5	-0.4	0.2	-0.4	0.1	-1.2	-1.0	-1.7	-0.2	-0.4	-0.9
Medication: Gliclazide	0.5	0.6	2.6	0.8	-0.2	0.3	0.5	-0.0	0.7	0.8	0.2	1.3	0.2	0.4	1.6
Eye problems/disorders: Glaucoma	0.5	0.6	3.9	-0.1	0.5	-0.2	-0.4	-0.9	-0.4	0.8	0.1	-0.3	-0.5	-0.8	-2.0
Medication: Paracetamol	0.5	0.8	2.4	0.5	1.2	1.0	1.6	0.8	0.5	0.2	1.1	0.5	1.2	0.8	0.4
Pain experienced in last month	0.5	0.9	2.5	-0.0	-0.3	-0.9	-1.6	-0.9	-0.0	-0.9	-1.4	-1.5	-0.8	-1.0	0.1
Intelligence (Savage-Jansen 2018)	0.4	1.3	3.4	1.6	1.1	1.1	0.6	1.3	1.9	0.5	0.7	0.4	1.3	1.1	1.2
Prostate Cancer	0.4	0.6	1.3	0.6	0.6	1.0	1.0	1.1	0.4	0.6	0.4	-0.3	1.1	1.0	0.2
Triglycerides	0.4	0.7	1.6	1.0	0.4	0.8	0.4	0.7	1.0	1.0	0.4	1.3	0.4	0.7	1.3
BMI	0.4	2.5	4.6	-0.2	-1.5	-1.9	-2.0	-2.1	-1.0	1.6	-0.3	1.9	-2.1	-1.9	-0.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.4	-0.6	-0.5	-0.8	-0.5	-0.7	-1.2	0.6	-0.2	0.6	-1.0	-0.7	-0.5
Ever used hormone-replacement therapy (HRT)	0.4	0.6	1.9	-0.8	0.4	0.3	0.8	0.5	-0.4	-1.4	0.2	-1.4	0.4	0.5	-0.8
Townsend deprivation index at recruitment	0.4	0.6	2.9	0.6	-0.1	-0.2	-0.3	0.0	-0.6	1.6	0.8	1.7	-0.0	-0.5	0.5
Medication: Atenolol	0.4	0.5	2.4	-1.1	-0.5	-0.3	0.1	-0.4	-0.6	-0.1	-0.5	-0.8	-0.4	0.0	-1.5
Sitting height	0.4	3.1	6.7	-2.4	-1.9	-1.4	-1.6	-1.3	-1.8	-1.6	-1.2	-1.7	-1.8	-1.2	-2.6
Chronic bronchitis/emphysema (father)	0.4	0.5	1.9	-0.7	-0.2	-0.7	-0.6	-0.4	-1.1	0.7	0.6	-0.4	-0.6	-0.5	-1.4
Arm fat percentage (right)	0.4	1.4	4.8	0.6	-0.9	-1.1	-1.0	-1.3	-0.3	2.0	-0.4	2.2	-1.1	-1.2	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.8	0.7	0.7	0.4	0.8	0.2	1.3	-0.5	0.1	-0.2	0.7	0.5	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.9	-0.1	0.1	0.5	0.0	0.2	-0.4	0.9	1.7	1.0	-0.1	0.6	0.1
Loud music exposure frequency	0.4	0.4	0.9	-0.3	-0.5	1.0	0.6	0.7	0.7	-0.4	-0.1	-0.9	0.9	0.9	0.2
Blood clot in the leg (DVT)	0.4	0.5	2.2	0.5	0.0	0.3	0.3	0.7	-0.3	0.2	0.6	1.4	0.2	0.5	1.5
Qualifications: College or University degree	0.4	1.2	5.3	1.4	1.3	0.1	0.1	0.1	-0.2	2.1	0.8	2.3	-0.5	0.2	0.1
Medication: Blood pressure	0.4	0.8	2.2	-0.4	-0.5	-0.8	-0.6	-0.9	-1.0	0.5	-0.9	0.9	-1.5	-0.8	-1.1
Whole body fat mass	0.4	1.5	2.9	-0.3	-1.5	-1.4	-1.3	-1.7	-0.6	1.1	-0.7	1.4	-1.5	-1.4	-0.5
Leg fat mass (right)	0.4	1.6	3.1	-0.5	-1.8	-1.5	-1.4	-1.7	-0.8	1.1	-0.8	1.3	-1.6	-1.5	-0.5
Arm fat percentage (left)	0.4	1.4	3.7	0.4	-1.1	-1.2	-1.1	-1.5	-0.3	1.8	-0.7	1.9	-1.2	-1.3	0.0
Ever had bowel cancer screening	0.4	0.4	1.3	1.2	1.1	0.1	0.5	0.2	0.0	0.3	0.3	1.0	0.1	-0.1	1.0
Average weekly champagne plus white wine intake	0.4	0.6	1.7	0.5	-0.0	0.8	0.9	0.4	1.2	-0.3	-0.8	-0.6	0.6	0.9	1.3
Ever taken oral contraceptive pill	0.4	0.4	2.2	0.7	-0.0	-0.2	0.2	-0.2	0.1	1.5	-0.1	1.4	0.1	-0.3	0.1
Diastolic blood pressure, automated reading	0.4	1.2	3.9	-1.3	-1.2	-0.9	-0.4	-0.3	-0.4	-2.0	-1.9	-1.3	-0.6	-0.8	0.2
Heart attack/myocardial infarction (self-reported)	0.4	0.6	1.3	-1.1	-0.5	-0.6	-0.7	-0.6	-0.6	-0.8	-0.6	-1.1	-0.8	-0.6	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.3	0.5	0.1	0.2	0.2	0.6	-0.4	0.3	0.7	1.5	-0.0	0.4	1.4
Bipolar Disorder or Schizophrenia	0.3	0.8	2.7	-0.7	-0.4	-0.8	-0.6	-0.9	-1.0	-0.1	-0.8	-1.4	-0.5	-0.8	-1.6
Depression (Nagel 2018)	0.3	0.4	1.0	0.4	1.0	0.7	0.9	0.8	0.4	-0.5	0.3	-0.7	0.7	0.6	0.3
Age at First Birth	0.3	0.5	2.1	0.8	1.5	0.4	0.2	0.0	0.5	0.8	1.1	0.7	0.1	0.1	-0.2
LDL Cholesterol	0.3	0.4	2.2	-0.8	-0.3	-0.5	-0.3	-0.7	-0.9	0.2	0.4	-0.2	-0.4	-0.6	-1.5
Schizophrenia (2014)	0.3	0.6	2.1	-0.5	0.0	-0.8	-0.3	-1.1	-0.9	0.3	-0.3	-0.7	-0.8	-0.8	-1.4
Cardiovascular Disease	0.3	0.9	2.2	-1.3	-1.1	-0.9	-0.6	-0.7	-1.5	-0.3	-0.3	0.1	-1.1	-0.8	-1.4
Chronotype (morning person)	0.3	0.8	3.3	0.7	0.7	0.0	0.4	-0.1	-0.1	1.8	1.2	1.8	0.1	-0.0	-0.1
Relative age of first facial hair	0.3	0.5	2.0	0.1	0.2	0.4	0.5	0.7	-1.0	-0.1	1.1	0.9	0.5	0.3	1.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.1	0.2	0.4	0.8	1.1	0.8	-0.1	0.2	0.5	0.2	0.8	0.7	0.3
Supplements: Zinc	0.3	0.3	1.6	0.4	0.8	0.4	0.2	0.3	-0.2	0.9	1.2	0.5	0.3	0.3	-0.5
Maternal smoking around birth	0.3	0.5	1.3	-0.6	-0.9	-0.9	-0.6	-0.7	-1.1	-0.1	-0.0	0.6	-0.7	-0.9	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.8	0.5	0.1	0.1	0.4	0.2	-0.2	0.8	1.4	2.0	0.4	0.0	1.1
Multivitamins +/- minerals	0.3	0.4	2.9	-0.2	1.0	0.2	0.6	-0.2	0.0	-0.2	1.7	-0.1	0.2	0.2	-0.7
Trunk fat mass	0.3	1.3	2.5	-0.2	-1.4	-1.4	-1.2	-1.6	-0.5	1.1	-0.7	1.2	-1.4	-1.3	-0.5
Past tobacco smoking	0.3	0.5	1.7	0.0	-0.7	0.3	-0.0	0.2	0.8	-1.1	-1.3	-0.7	0.0	0.4	1.2
Medication: Simvastatin	0.3	0.4	1.9	0.0	-0.2	-0.5	-0.3	-0.5	-0.5	1.4	0.4	1.1	-0.5	-0.4	-0.3
Father’s age at death	0.3	0.4	1.3	0.4	-0.2	-0.6	-0.7	-0.2	-0.8	1.1	-0.4	0.9	-0.5	-0.7	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	3.1	-0.8	0.5	-0.2	-0.1	0.0	-1.8	0.3	0.9	0.5	-0.4	-0.4	-0.9
Falls in the last year	0.3	0.4	1.5	-1.2	-1.2	-0.2	-0.5	-0.1	-0.9	-0.1	0.6	0.3	-0.3	-0.0	-0.2
Mouth/teeth dental problems: Dentures	0.3	0.6	1.6	0.4	0.8	0.9	1.3	0.6	1.1	0.1	0.3	-0.4	1.0	0.7	-0.4
Depression (self-reported)	0.3	0.4	1.3	1.1	0.3	0.4	0.3	0.5	0.4	0.5	0.0	1.1	0.5	0.3	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.1	-1.4	-1.2	-1.0	-1.0	-1.0	-1.2	-0.2	0.0	-0.1	-1.1	-0.9	-1.2
Pulse wave Arterial Stiffness index	0.3	0.3	1.0	-0.1	0.1	0.5	0.5	0.5	0.7	-0.9	-1.0	-0.9	0.3	0.5	0.0
Tense / ‘highly strung’	0.3	0.4	1.4	-0.1	-0.4	0.4	1.2	0.6	0.5	-0.6	-0.5	0.1	0.7	0.6	1.1
Pulse wave reflection index	0.3	0.3	0.9	-0.4	-0.4	-0.5	-0.5	-0.3	-0.4	-0.6	-0.8	-0.7	-0.7	-0.4	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.8	0.7	0.9	0.3	0.5	0.7	-0.2	0.7	0.7	0.6	0.4	0.5	0.3
Number of full brothers	0.3	0.4	1.0	0.2	0.3	0.9	0.6	0.7	0.9	-0.1	0.7	-0.1	0.7	1.0	0.6
Pulse wave peak to peak time	0.3	0.3	0.7	-0.3	-0.4	-0.6	-0.6	-0.6	-0.9	0.6	0.7	0.6	-0.5	-0.6	-0.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.0	0.3	0.2	0.7	0.6	0.6	0.7	-0.0	-0.9	-1.0	0.6	0.6	-0.4
Number of full sisters	0.3	0.3	0.9	0.5	0.3	-0.6	-0.7	-0.4	-0.4	1.0	0.9	0.6	-0.3	-0.5	-0.2
Chest pain or discomfort	0.3	0.4	1.8	-0.1	0.5	-0.4	-0.4	-0.5	-1.4	0.6	0.4	0.3	-0.7	-0.6	-0.9
Age at last live birth	0.3	0.5	3.0	-0.3	0.5	-0.4	0.2	-0.8	-0.8	0.8	0.4	0.0	-0.5	-0.5	-1.7
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.3	-1.3	-0.6	-0.6	-0.8	-0.5	-0.5	-1.5	-0.1	-1.1	-0.5	-0.7	-0.5
Friendships satisfaction	0.3	0.4	1.9	1.4	1.0	-0.1	-0.5	-0.0	-0.5	0.8	0.1	0.6	-0.3	-0.4	0.5
Back pain experienced in last month	0.3	0.4	1.1	0.0	0.6	0.8	1.0	1.0	0.0	0.2	0.6	-0.2	0.9	0.8	-0.0
Wears glasses or contact lenses	0.3	0.4	1.1	-0.8	-0.4	0.4	0.5	0.4	-0.0	-0.8	-0.2	-1.1	0.5	0.4	-0.8
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.8	0.0	-0.6	-0.5	-0.9	-0.4	-0.5	-0.6	-0.8	-0.1	-0.5	-0.6	0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.6	-0.1	0.3	-0.6	-0.3	-0.4	-1.0	0.7	0.1	0.1	-0.5	-0.5	-1.3
Medication: Atorvastatin	0.3	0.3	1.2	0.7	0.7	0.3	-0.1	0.4	0.5	1.1	0.5	0.8	0.1	0.3	0.3
Number of operations (self-reported)	0.3	0.5	1.1	0.3	0.4	0.6	0.7	1.0	0.9	-0.7	0.4	0.1	0.9	0.9	1.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.0	0.6	0.8	-0.4	0.0	-0.1	-0.4	0.9	-0.2	1.0	-0.3	-0.7	-0.2
Age started oral contraceptive pill	0.3	0.4	1.6	-0.8	-0.3	0.1	0.6	-0.1	0.1	-1.3	-0.4	-1.2	0.1	0.4	-0.4
Myopia	0.3	0.5	1.7	-1.2	-0.2	-0.5	-0.0	-0.2	-0.4	-1.3	-0.1	-1.1	-0.0	-0.4	-0.6
Basal cell carcinoma (self-reported)	0.3	0.4	1.0	0.2	0.6	1.0	0.9	1.0	0.3	-0.3	0.2	-0.1	0.6	0.9	0.4
Leg fat mass (left)	0.3	1.2	2.6	-0.3	-1.6	-1.2	-1.2	-1.4	-0.5	1.0	-0.7	1.3	-1.3	-1.2	-0.2
Bipolar Disorder (2018)	0.2	0.3	1.4	-0.3	-0.3	0.4	0.1	0.6	-0.0	-0.3	-0.6	-1.2	0.6	0.2	-0.5
Neuroticism (Nagel 2018)	0.2	0.6	2.2	-1.2	-0.4	-0.2	0.1	-0.3	-0.9	-0.6	-0.5	-1.2	-0.2	-0.3	-1.5
Primary Biliary Cirrhosis	0.2	0.2	0.6	0.8	-0.1	0.1	-0.1	0.2	0.6	-0.1	-0.8	-0.8	0.4	0.0	0.7
Blood White Count	0.2	1.1	4.5	-0.6	-0.4	-0.6	-0.8	-0.2	-0.7	-0.4	-1.7	-2.1	-0.5	-0.6	-1.9
Heel T-Score	0.2	1.8	4.2	-0.4	-1.1	-1.9	-1.9	-1.8	-1.4	-0.4	-0.5	1.1	-1.7	-2.0	0.4
Lung FEV1/FVC ratio	0.2	1.3	2.3	-0.9	-0.9	-1.1	-0.9	-1.3	-1.5	0.7	0.7	1.2	-1.4	-1.0	-1.5
Diabetes (mother)	0.2	0.2	0.6	-0.7	-0.7	0.1	0.0	0.2	-0.5	-0.8	-0.5	-0.0	-0.1	0.3	0.4
Pack years adult smoking proportion	0.2	0.3	0.7	-0.1	0.3	0.5	0.5	0.8	0.6	-0.7	0.0	0.1	0.7	0.4	0.7
Trunk fat percentage	0.2	0.7	3.1	1.0	-0.2	-0.0	0.2	-0.2	0.8	1.8	0.1	1.8	0.1	-0.0	0.6
Hand grip strength (right)	0.2	0.6	2.7	1.0	0.7	0.2	-0.1	-0.2	-0.1	0.8	1.6	1.7	0.0	-0.2	0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.3	0.5	0.8	0.1	0.4	-0.1	1.2	-0.4	0.3	-0.7	0.5	0.1	0.2
High blood pressure (mother)	0.2	0.3	0.5	0.0	0.7	0.7	0.6	0.7	0.4	-0.2	0.5	-0.0	0.5	0.7	-0.1
Alcohol usually taken with meals	0.2	0.3	1.1	-1.1	-0.3	-0.5	-0.3	-0.6	-0.6	-0.6	0.2	0.1	-0.6	-0.3	-0.5
Hearing difficulty/problems with background noise	0.2	0.3	0.7	0.2	-0.1	0.5	0.9	0.8	0.2	-0.5	-0.8	-0.1	0.6	0.5	0.6
Had menopause	0.2	0.3	0.9	-0.3	0.8	0.4	0.4	0.5	-0.1	-0.6	0.5	-0.9	0.3	0.7	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.4	0.1	0.1	-0.5	-0.4	-0.5	-0.6	0.4	1.1	1.2	-0.4	-0.5	0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.8	-0.1	0.9	0.3	0.7	0.7	-0.8	-0.2	0.8	0.1	0.6	0.1	0.0
Qualifications: None of the above	0.2	0.5	1.9	-0.6	-0.4	0.5	0.8	0.3	0.7	-1.1	-0.2	-1.4	0.8	0.4	0.3
Time employed in main current job	0.2	0.2	0.5	-0.1	0.6	0.6	0.7	0.5	0.2	0.2	0.4	-0.4	0.4	0.5	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.7	-1.1	-0.8	-0.9	-1.0	-0.7	-1.3	0.0	0.2	0.2	-1.1	-0.8	-1.0
Lung cancer (father)	0.2	0.2	0.7	0.3	0.7	-0.2	-0.3	-0.2	0.1	0.4	0.6	-0.5	-0.1	0.1	-0.9
Headache pain in last month	0.2	0.3	1.2	-0.5	-0.1	0.2	0.7	0.0	0.1	0.5	1.1	0.8	0.5	0.2	-0.3
Glaucoma (self-reported)	0.2	0.2	0.4	0.3	0.7	0.6	0.4	0.1	0.5	0.0	0.2	-0.5	0.5	0.1	-0.6
Forced vital capacity (FVC), Best measure	0.2	0.9	2.4	-1.6	-1.1	-0.9	-0.8	-0.8	-1.1	-0.4	-0.0	-0.5	-0.9	-0.8	-1.3
Body fat percentage	0.2	0.7	3.3	0.9	-0.5	-0.2	-0.0	-0.5	0.5	1.8	-0.1	1.8	-0.2	-0.3	0.6
Leg fat percentage (right)	0.2	0.8	4.1	0.9	-0.4	-0.2	0.1	-0.5	0.5	1.9	0.1	2.0	-0.1	-0.3	0.7
Exposure to tobacco smoke outside home	0.2	0.2	0.8	-0.2	-0.8	-0.4	-0.3	-0.4	-0.1	0.0	-0.3	0.9	-0.5	-0.4	0.8
Age at first live birth	0.2	0.3	0.7	0.3	0.6	0.6	0.8	0.6	0.5	-0.1	0.1	0.1	0.4	0.8	0.6
Health satisfaction	0.2	0.3	1.2	-0.1	-0.2	-0.1	-0.1	0.1	-0.2	-0.9	-1.1	-0.5	-0.1	-0.2	0.8
Suffer from ‘nerves’	0.2	0.3	0.9	-1.0	-0.9	-0.5	-0.3	-0.4	-0.9	0.1	-0.1	0.4	-0.6	-0.4	-0.5
Overall health rating	0.2	0.5	2.7	0.7	-0.2	0.1	-0.0	0.5	0.4	-0.4	-1.4	0.2	0.0	0.1	1.6
Had major operations	0.2	0.2	0.5	0.5	0.1	-0.6	-0.0	-0.6	-0.5	0.7	0.0	0.7	-0.6	-0.6	-0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.6	-0.4	-0.5	-0.0	-0.7	0.1	-0.0	-0.4	-0.4	-0.8	-0.3	0.0	-0.7
Knee pain experienced in last month	0.2	0.3	1.4	-0.2	-0.2	0.4	0.8	0.6	-0.0	0.2	0.6	1.2	0.5	0.4	0.4
Illnesses of siblings: Diabetes	0.2	0.3	1.8	0.6	0.4	-0.1	-0.2	0.2	-0.0	1.3	0.1	0.8	-0.1	0.2	-0.4
Smoking status: Previous	0.2	0.3	1.2	0.4	0.5	0.2	0.6	0.2	0.1	0.5	1.1	0.8	0.3	0.2	0.2
Miserableness	0.2	0.3	1.2	-1.1	-0.6	-0.3	0.2	-0.3	-1.1	-0.5	-0.2	-0.2	-0.2	-0.4	-0.4
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.6	-0.0	0.1	0.4	0.7	0.6	-0.3	0.7	-0.1	0.2	0.4	0.4	-0.4
High cholesterol (Self-reported)	0.2	0.4	1.1	-0.2	-0.4	-0.6	-0.6	-0.2	-1.1	0.8	0.1	1.0	-0.7	-0.5	0.3
Illnesses of father: High blood pressure	0.2	0.2	0.7	0.8	-0.3	0.0	-0.7	0.0	0.4	0.1	-0.7	0.5	-0.5	0.0	0.7
Leg fat percentage (left)	0.2	0.8	4.0	1.0	-0.3	-0.0	0.2	-0.3	0.8	1.7	0.2	2.0	-0.0	-0.1	1.1
Commuting to job workplace: Cycle	0.2	0.3	1.3	-0.0	-0.0	-0.7	-0.7	-0.2	-1.1	-0.3	-0.1	0.2	-0.7	-0.6	0.3
Depressed Affect (Nagel 2018)	0.1	0.2	0.7	-0.1	0.2	0.6	0.8	0.5	0.3	-0.2	-0.1	-0.7	0.6	0.6	0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	1.3	-0.1	-0.1	0.1	-0.0	0.4	-0.1	-0.9	0.2	0.4	0.1	0.3	1.1
Irritable Bowel Disease (IBD)	0.1	0.3	1.5	-0.2	-0.7	0.2	-0.1	0.2	-0.1	-0.2	-1.1	-1.2	0.1	0.2	-0.6
Fasting Glucose	0.1	0.1	0.7	0.1	-0.1	-0.5	-0.8	-0.2	-0.2	0.2	0.4	0.2	-0.4	-0.5	0.2
HbA1C	0.1	0.1	0.8	0.1	-0.0	0.2	0.3	0.3	-0.3	-0.1	0.5	0.5	-0.0	0.1	0.9
Blood Red Count	0.1	1.1	3.7	-0.0	0.2	-0.8	-1.0	-1.3	0.6	-0.3	-0.6	-1.9	-0.5	-1.0	-1.9
Waist Hip Ratio (WHR)	0.1	0.4	1.1	-0.0	-0.0	-0.6	-0.7	-0.4	-0.4	-1.0	-0.7	-1.0	-0.3	-0.7	0.5
Smoking Status	0.1	0.2	0.9	-0.2	0.2	-0.7	-0.4	-0.6	-0.3	-0.1	0.2	-0.1	-0.4	-0.7	-0.9
Neuroticism	0.1	0.2	0.7	-0.1	-0.1	-0.3	-0.3	-0.1	-0.2	-0.1	-0.8	-0.5	-0.6	-0.2	-0.6
Hair Pigment	0.1	1.8	3.7	-0.7	-0.4	-1.7	-1.6	-1.5	-1.0	0.4	-1.4	-1.0	-1.5	-1.8	-1.9
Systolic blood pressure, automated reading	0.1	0.2	1.1	0.4	0.4	0.2	0.3	-0.0	0.1	-0.3	0.1	1.0	-0.1	0.0	1.0
Diabetes (father)	0.1	0.1	0.3	-0.1	-0.1	-0.1	-0.3	-0.4	-0.2	0.1	-0.6	-0.4	-0.2	-0.3	-0.2
Fed-up feelings	0.1	0.1	0.5	-0.2	-0.7	-0.2	0.1	-0.2	-0.4	0.2	-0.6	0.4	-0.2	-0.2	-0.0
Forced vital capacity (FVC)	0.1	0.5	1.1	-1.0	-0.5	-0.8	-0.6	-0.4	-1.0	-0.3	-0.1	-0.3	-0.8	-0.6	-1.0
Medication: Ramipril	0.1	0.1	0.4	-0.5	-0.6	-0.3	-0.1	-0.2	-0.0	-0.1	-0.1	0.4	-0.2	-0.3	0.2
Neuroticism score	0.1	0.3	0.6	-0.1	-0.2	0.5	0.7	0.8	0.2	-0.4	-0.8	-0.5	0.4	0.7	0.3
Worrier / anxious feelings	0.1	0.1	0.5	0.1	-0.1	0.3	0.1	0.2	-0.6	0.7	-0.3	0.2	-0.0	0.0	-0.7
Medication: Cholesterol lowering	0.1	0.1	0.4	-0.2	0.4	0.1	0.2	-0.0	-0.0	0.7	0.5	0.3	-0.0	0.1	-0.5
Medication: Lansoprazole	0.1	0.1	0.3	0.1	0.1	-0.2	-0.1	-0.2	0.4	-0.5	-0.5	0.1	-0.2	-0.2	0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.8	0.2	0.2	0.6	0.9	0.2	0.4	0.0	-0.3	-0.5	0.6	0.3	-0.3
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.6	0.6	-0.1	0.4	0.1	0.5	0.6	-0.1	-0.2	-0.5	0.8	0.3	0.7
Migraine (self-reported)	0.1	0.1	0.3	-0.2	0.2	0.0	0.6	0.3	-0.1	0.5	0.4	0.6	0.4	0.1	-0.4
Pulse rate, automated reading	0.1	0.4	1.4	0.5	-0.2	-0.6	-0.0	-0.7	0.3	0.8	-1.2	0.7	-0.6	-0.7	-0.4
Alcohol intake frequency.	0.1	0.1	0.4	-0.6	-0.2	-0.2	-0.4	-0.2	-0.6	-0.6	-0.1	-0.3	-0.5	-0.1	-0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.6	-0.1	0.3	0.3	0.3	0.2	0.5	-0.8	0.2	-0.6	0.3	0.2	0.3
Qualifications: nursing, teaching	0.1	0.1	0.5	-0.1	0.3	-0.3	-0.2	-0.4	-0.5	0.4	-0.2	0.1	-0.4	-0.3	-0.7
Number of self-reported non-cancer illnesses	0.1	0.2	0.5	0.4	0.7	-0.1	0.1	0.1	-0.7	0.3	0.3	0.6	-0.2	-0.1	0.4
Irritability	0.1	0.1	0.5	-0.4	-0.2	0.2	0.4	0.2	-0.1	-0.7	-0.1	-0.4	0.1	0.2	-0.3
Pack years of smoking	0.1	0.1	0.5	-0.1	0.3	0.4	0.4	0.7	0.2	-0.4	0.1	0.1	0.6	0.3	0.3
Blood Platelet Count	0.0	0.1	0.2	-0.1	0.0	0.2	0.5	0.2	-0.1	0.2	0.4	0.5	0.2	0.0	0.0
Systolic Blood Pressure	0.0	0.2	1.0	-0.2	0.3	0.4	0.6	0.3	-0.0	-0.0	0.7	1.0	0.0	0.3	0.2
Lung FVC	0.0	0.1	0.8	-0.1	0.1	0.0	-0.1	0.3	-0.4	0.9	-0.2	-0.0	-0.1	-0.2	-0.4
Tanning	0.0	0.4	1.9	-0.6	0.0	-0.6	-0.6	-0.6	-0.8	0.3	-0.3	-0.1	-0.8	-0.6	-1.4
Hand grip strength (left)	0.0	0.1	0.5	0.4	0.2	0.0	0.2	-0.3	0.1	-0.1	0.7	0.4	-0.1	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.4	0.1	-0.5	-0.2	0.1	-0.5	0.2	0.7	0.2	0.4	-0.1	-0.2	-0.0
Medication: Lisinopril	0.0	0.1	0.4	0.0	0.2	-0.1	0.1	0.1	-0.4	0.4	0.1	0.1	-0.1	-0.0	-0.6

Hub : Genes

UGT3A2

Models

Trait associations