TWAS hub - CAPSL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.0512	0.0219	0.0022	0.022	0.020	0.020	0.021	0.025	0.0006	0.00110	0.0011	0.00089	0.00029
2	TCGA	Prostate Adenocarcinoma	0.0568	0.0327	0.0034	0.009	0.027	0.021	NA	0.021	0.0340	0.00071	0.0023	NA	0.00270

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Allergy or Eczema	13.7	36.1	71.6	-8.5	-0.8
Hayfever, allergic rhinitis or eczema	9.4	20.5	41.0	-6.4	-0.0
Allergy	7.1	16.3	32.1	5.7	0.7
Primary Biliary Cirrhosis	6.3	9.0	11.2	-3.3	-2.6
Hearing difficulty/problems: Yes	4.6	7.0	10.1	-2.0	-3.2
Commuting to job workplace: Car/motor vehicle	3.9	4.5	5.8	2.4	1.8
Medication: Ibuprofen	3.4	4.0	5.9	1.5	2.4
Age at first live birth	3.1	5.4	10.4	0.7	3.2
Hearing difficulty/problems with background noise	3.0	4.8	6.6	-1.7	-2.6
Hayfever/allergic rhinitis (self-reported)	2.9	3.9	6.8	-2.6	1.0
Mouth/teeth dental problems	2.8	4.2	6.5	2.6	1.4
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.5	5.5	1.2	2.4
Medication for pain relief, constipation, heartburn	2.6	4.5	5.1	-2.3	-2.0
Chronic bronchitis/emphysema (father)	2.5	3.0	5.0	0.9	2.2
Osteoporosis (self-reported)	2.5	3.1	5.8	0.6	-2.4
Neuroticism score	2.3	4.7	5.7	-1.9	-2.4
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	6.0	-1.3	-2.5
Worry too long after embarrassment	2.3	3.9	7.1	-0.8	-2.7
Medication: Blood pressure	2.3	4.1	7.3	1.0	2.7
Angina	2.2	2.9	5.6	0.5	2.4
Worrier / anxious feelings	2.2	4.1	5.8	-1.6	-2.4
Leg pain on walking	2.2	2.8	5.5	-0.3	2.4
Medication: Ventolin 100micrograms inhaler	2.1	2.7	3.8	-2.0	-1.3
Neck or shoulder pain in last month	2.1	3.0	4.1	2.0	-1.4
Number of live births	2.0	2.9	5.5	0.5	-2.3
Emphysema/chronic bronchitis	2.0	2.3	3.6	-1.0	-1.9
Illnesses of father: None of the above (group 1)	2.0	2.4	4.0	-0.9	-2.0
Bipolar Disorder (2018)	1.9	3.0	4.2	-1.4	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.9	2.5	3.0	-1.4	1.7
Angina (self-reported)	1.9	2.5	4.7	0.6	2.2
Loneliness, isolation	1.9	2.7	5.2	-2.3	0.3
Breast cancer (self-reported)	1.9	2.3	3.4	1.1	1.8
Alcohol drinker status: Never	1.9	2.3	4.4	-2.1	0.5
Prostate Cancer	1.8	2.6	5.1	-2.3	0.2
Lupus	1.8	2.8	2.8	-1.7	-1.7
Hypothyroidism (self reported)	1.8	4.1	5.7	-2.4	-1.6
Medication: Levothyroxine sodium	1.8	3.1	3.5	-1.6	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.8	2.9	5.9	-0.0	-2.4
Glaucoma (self-reported)	1.8	2.2	2.2	-1.5	-1.4
Birth weight	1.8	3.8	7.0	-0.8	-2.6
Relative age voice broke	1.7	2.6	5.2	-2.3	-0.3
Age when periods started (menarche)	1.7	4.1	7.5	-2.7	-0.9
Had other major operations	1.7	2.1	3.3	1.8	-0.9
Gout (self-reported)	1.7	2.3	3.8	1.9	1.0
Suffer from ‘nerves’	1.7	2.7	5.3	-0.4	-2.3
Long-standing illness, disability or infirmity	1.7	2.6	4.9	0.5	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	4.3	2.1	1.6
Pain experienced in last month	1.7	2.8	5.6	-2.4	-0.2
Worry (Nagel 2018)	1.6	3.3	6.1	-0.7	-2.5
Number of incorrect matches in round	1.6	2.6	4.8	-2.2	-0.6
Schizophrenia vs Biploar Disorder	1.5	2.0	3.3	0.8	1.8
Blood Eosinophil Count	1.5	11.6	21.4	-4.6	1.3
Lung FEV1/FVC ratio	1.5	7.6	14.7	3.8	-0.8
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	2.4	1.6	0.9
Lung cancer (father)	1.5	1.8	3.0	-0.8	-1.7
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	3.5	-1.6	-1.9
Friendships satisfaction	1.5	1.9	2.3	-1.5	1.2
Age at First Birth	1.4	2.1	3.3	0.9	1.8
Neuroticism (2016)	1.4	2.0	3.9	0.3	-2.0
Serious illness, injury or assault to yourself	1.4	1.7	3.3	1.8	0.2
Asthma	1.4	2.8	5.0	-2.2	-0.7
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	2.2	-1.5	1.0
Medication: Ramipril	1.3	1.6	3.0	0.6	1.7
Happiness	1.3	1.6	2.2	-1.5	1.0
Noisy workplace	1.3	1.6	3.2	-0.1	1.8
Birth weight of first child	1.3	2.4	4.0	-2.0	0.9
Age at last live birth	1.3	1.9	2.4	1.2	1.6
Family relationship satisfaction	1.3	1.6	2.1	-1.0	-1.5
Medication for cholesterol	1.3	1.9	2.4	-1.6	1.2
Illnesses of father: High blood pressure	1.3	1.6	2.1	-1.1	1.4
Average weekly beer plus cider intake	1.3	1.8	3.7	-1.9	0.0
Type 2 Diabetes (T2D) (2012)	1.2	1.3	2.6	-0.2	1.6
Blood White Count	1.2	9.1	17.6	-4.2	-0.8
Respiratory disease	1.2	2.7	4.4	-2.1	-1.0
Mouth/teeth dental problems: Dentures	1.2	2.0	3.5	-0.7	-1.9
Migraine (self-reported)	1.2	1.5	2.9	1.7	-0.4
Medication: Allopurinol	1.2	1.6	1.6	1.3	1.3
Knee pain experienced in last month	1.2	1.9	3.6	1.9	0.4
Ever taken oral contraceptive pill	1.2	1.3	2.0	1.4	0.8
Tinnitus: Yes, now most or all of the time	1.2	1.5	2.9	-0.2	1.7
High cholesterol (Self-reported)	1.2	2.1	3.8	1.9	0.6
Age started oral contraceptive pill	1.2	1.5	3.1	-0.0	-1.8
Cholesterol lowering medication	1.2	1.8	3.3	1.8	-0.6
Alzheimer’s Disease (including proxy)	1.1	1.7	3.1	-0.5	-1.8
Multivitamins +/- minerals	1.1	1.4	1.6	1.3	1.1
Depression (self-reported)	1.1	1.3	1.3	-1.2	-1.1
Breastfed as a baby	1.1	1.4	2.6	0.4	1.6
Ever had bowel cancer screening	1.1	1.3	1.4	1.2	1.1
Eye problems/disorders: Glaucoma	1.1	1.3	2.2	-0.7	-1.5
Arm fat-free mass (left)	1.1	5.5	8.6	2.9	-1.5
Arm predicted mass (left)	1.1	5.7	8.2	2.9	-1.8
Major Depression (MDD)	1.0	1.2	2.1	-0.5	-1.5
Ovarian Cancer	1.0	1.4	2.0	1.4	0.9
Severe depression (siblings)	1.0	1.1	1.8	-0.7	1.3
Taking other prescription medications	1.0	1.5	2.9	-0.3	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	4.4	0.0	-2.1
Nervous feelings	1.0	1.8	3.2	-0.7	-1.8
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	3.1	-1.8	0.4
Hair/balding pattern: Pattern 2	1.0	1.3	2.0	0.8	1.4
Qualifications: College or University degree	1.0	3.2	4.5	1.3	2.1
Medication: Aspirin	1.0	1.3	1.8	0.9	1.4
Illnesses of siblings: Diabetes	1.0	1.3	1.4	-1.2	-1.1
Back pain experienced in last month	1.0	1.4	2.3	1.5	-0.7
Medication: Gliclazide	1.0	1.1	1.5	0.8	1.2
Miserableness	1.0	1.7	2.2	-1.1	-1.5
Medication: Blood pressure	1.0	1.9	2.2	1.5	-1.2
Unable to work because of sickness or disability	1.0	1.3	2.1	0.7	1.5
Depression (Nagel 2018)	0.9	1.3	2.6	-1.6	0.2
HbA1C	0.9	1.0	1.8	-0.5	1.3
Chronotype (morning person)	0.9	2.0	3.5	0.7	-1.9
Ever had hysterectomy (womb removed)	0.9	1.0	2.0	-1.4	0.2
Medication for hormone replacement therapy	0.9	1.0	1.1	0.9	1.0
Fed-up feelings	0.9	1.6	2.8	-0.6	-1.7
Supplements: Glucosamine	0.9	1.1	1.9	-0.5	1.4
Body mass index (BMI)	0.9	3.8	7.6	2.8	-0.2
Arm fat mass (right)	0.9	3.7	7.3	2.7	-0.1
Exposure to tobacco smoke at home	0.9	1.1	1.2	-1.1	0.9
Arm fat-free mass (right)	0.9	4.4	4.5	2.1	-2.1
Health satisfaction	0.9	1.1	2.2	0.2	1.5
Arm predicted mass (right)	0.9	4.8	5.0	2.2	-2.1
Pulse rate, automated reading	0.9	3.1	5.9	-0.4	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.0	0.4	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	1.4	1.2	0.7
Asthma (self-reported)	0.9	1.7	2.9	-1.7	-0.7
Medication: Aspirin	0.9	1.1	1.4	1.0	1.2
Leg fat percentage (left)	0.9	3.4	6.7	2.6	0.4
Neuroticism (Nagel 2018)	0.8	1.9	3.3	-0.6	-1.8
Schizophrenia (2018)	0.8	1.6	2.6	-0.8	1.6
Ulcerative Colitis (UC)	0.8	1.4	2.7	-1.6	-0.3
Neuroticism	0.8	1.9	2.4	-1.2	-1.6
Average weekly spirits intake	0.8	1.0	1.8	1.3	-0.5
Sensitivity / hurt feelings	0.8	1.4	2.3	-0.7	-1.5
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.1	-0.8	-1.1
Waist circumference	0.8	2.8	5.6	2.4	-0.0
Heart attack	0.8	1.0	1.2	0.9	1.1
Weight	0.8	4.1	7.7	2.8	-0.8
Trunk fat-free mass	0.8	4.4	4.6	2.1	-2.1
Hip circumference	0.8	3.3	6.6	2.6	-0.3
Hair/balding pattern: Pattern 3	0.8	1.2	2.3	-1.5	-0.4
Illnesses of mother	0.8	1.0	1.8	-1.3	0.4
Impedance of arm (left)	0.8	3.9	6.7	-2.6	1.1
Tense / ‘highly strung’	0.8	1.4	1.5	-1.2	-1.1
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	1.1	-1.0	1.0
Medication: Paracetamol	0.8	1.3	1.8	0.9	1.4
Leg fat percentage (right)	0.8	3.0	6.1	2.5	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	2.0	-1.4	0.1
Wheeze or whistling in the chest in last year	0.8	1.5	1.6	-1.1	-1.3
Mean time to correctly identify matches	0.8	1.5	2.3	0.8	1.5
Leg fat mass (right)	0.8	3.1	5.9	2.4	-0.5
Chest pain or discomfort	0.8	1.2	2.1	-1.4	-0.6
Osteoarthritis (self-reported)	0.8	1.0	1.0	1.0	1.0
Commuting to job workplace: Public transport	0.8	0.9	1.6	-0.5	-1.3
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.5	1.2	0.7
Medication: Lisinopril	0.8	1.0	1.0	-1.0	1.0
Risk taking	0.8	1.1	1.6	1.3	0.8
Ever depressed for a whole week	0.8	1.0	1.9	-1.4	0.3
Leg fat mass (left)	0.8	3.1	6.0	2.4	-0.4
Irritable Bowel Disease (IBD)	0.7	1.7	3.3	-1.8	0.1
Ulcerative Colitis	0.7	1.0	1.8	-1.3	-0.4
Alcohol usually taken with meals	0.7	1.1	2.1	1.4	-0.4
Had menopause	0.7	0.9	1.6	-0.4	-1.3
Arm fat percentage (right)	0.7	2.6	5.1	2.3	0.3
Pulse rate	0.7	1.2	2.0	-0.6	-1.4
Trunk predicted mass	0.7	4.1	4.2	2.0	-2.0
Pulse wave reflection index	0.7	0.9	1.4	-1.2	-0.7
Loud music exposure frequency	0.7	0.8	1.5	-1.2	-0.2
Headache pain in last month	0.7	1.1	1.8	1.3	0.7
Exposure to tobacco smoke outside home	0.7	1.0	1.2	0.8	-1.1
Number of full brothers	0.7	0.9	1.8	0.2	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.4	-0.5	1.2
Whole body fat mass	0.7	3.1	6.2	2.5	-0.2
Whole body fat-free mass	0.7	4.2	4.8	1.9	-2.2
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	1.7	-1.3	-0.7
Whole body water mass	0.7	4.1	4.3	2.0	-2.1
Arm fat mass (left)	0.7	2.7	5.5	2.3	-0.1
Mother’s age at death	0.7	0.9	1.0	0.9	1.0
Financial situation satisfaction	0.7	0.9	1.6	-1.3	-0.5
Medication: Paracetamol	0.7	1.0	1.2	0.9	1.1
Basal metabolic rate	0.7	3.9	4.2	2.0	-1.9
Fractured/broken bones in last 5 years	0.7	0.9	1.5	1.2	-0.6
Supplements: Calcium	0.7	0.8	0.8	0.9	-0.9
Rheumatoid Arthritis	0.6	0.8	1.2	-1.1	0.6
Medication: Co-codamol	0.6	0.7	0.9	-0.7	1.0
Diabetes (father)	0.6	0.8	1.2	1.1	0.5
Leg fat-free mass (left)	0.6	3.2	4.5	1.4	-2.1
Trunk fat percentage	0.6	2.2	3.9	2.0	0.7
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.2	-1.1	0.1
Medication: Atenolol	0.6	0.8	1.5	1.2	-0.1
Leg predicted mass (left)	0.6	3.2	4.4	1.4	-2.1
Trunk fat mass	0.6	2.7	5.3	2.3	0.1
Pain all over the body in last month	0.6	0.6	1.0	-0.5	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	3.6	1.9	0.0
Peak expiratory flow (PEF)	0.6	1.4	2.2	1.5	-0.8
Chronic bronchitis/emphysema (mother)	0.6	0.6	0.9	1.0	0.6
Body fat percentage	0.6	2.5	4.7	2.2	0.6
Number of children fathered	0.6	0.7	1.0	0.6	1.0
Eye problems/disorders: None of the above	0.6	0.7	1.2	-1.1	-0.4
Medication: Omeprazole	0.6	0.7	1.1	0.6	-1.1
Medication: Seretide 50 evohaler	0.6	0.7	1.3	-1.2	0.3
Heart disease (mother)	0.6	0.8	1.5	0.3	-1.2
Average weekly red wine intake	0.6	0.8	1.7	1.3	-0.2
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.0	-1.0	-0.7
Mood swings	0.6	1.1	1.5	-1.2	-0.8
Wears glasses or contact lenses	0.6	0.7	1.2	-0.5	-1.1
Number of operations (self-reported)	0.6	0.8	0.9	0.9	-1.0
Heart disease (siblings)	0.6	0.7	1.4	1.2	-0.3
Impedance of whole body	0.6	2.8	3.4	-1.8	1.5
Depressed Affect (Nagel 2018)	0.5	1.0	1.1	-1.1	-1.0
Alzheimer’s Disease (in mother)	0.5	0.6	0.8	0.7	-0.9
Reaction Time	0.5	0.9	1.0	1.0	0.9
Bipolar Disorder (2011)	0.5	0.5	0.6	-0.8	-0.5
BMI	0.5	3.2	6.2	2.5	-0.4
Type 2 Diabetes (T2D) (2018)	0.5	1.0	1.7	0.4	1.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.3	-1.2	0.1
Supplements: Zinc	0.5	0.6	1.1	1.0	-0.3
Townsend deprivation index at recruitment	0.5	0.7	1.3	-1.2	-0.1
Average weekly fortified wine intake	0.5	0.6	0.9	-1.0	-0.5
Fluid intelligence score	0.5	1.1	2.2	-1.5	-0.1
Father’s age at death	0.5	0.7	1.2	-0.3	-1.1
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	3.6	1.9	0.3
Medication: Cholesterol lowering	0.5	0.8	0.8	0.9	0.8
Medication: Lansoprazole	0.5	0.5	0.8	0.5	-0.9
Pulse wave Arterial Stiffness index	0.5	0.6	1.0	-1.0	-0.5
Number of full sisters	0.5	0.6	0.7	0.7	0.8
Leg fat-free mass (right)	0.5	2.9	3.8	1.4	-2.0
Arm fat percentage (left)	0.5	2.0	3.8	2.0	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	0.6	-0.7	-0.8
Smoking status: Current	0.5	0.8	1.5	-0.3	-1.2
Leg predicted mass (right)	0.5	2.8	3.6	1.4	-1.9
Number of self-reported non-cancer illnesses	0.5	0.9	1.6	-1.3	-0.3
Average weekly champagne plus white wine intake	0.5	0.7	1.0	-0.7	1.0
Myopia	0.5	0.7	1.4	1.2	0.3
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.0	0.6	1.0
Bipolar Disorder or Schizophrenia	0.4	1.0	2.1	-1.4	-0.0
Alzheimer’s Disease (in father)	0.4	0.4	0.7	-0.9	-0.4
Coronary Artery Disease (CAD)	0.4	0.4	0.6	-0.8	-0.5
Lung FVC	0.4	2.2	4.4	-0.2	2.1
Tanning	0.4	4.8	5.7	2.4	2.0
High blood pressure (mother)	0.4	0.6	1.1	0.0	1.1
Impedance of leg (left)	0.4	2.1	3.0	-1.1	1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	1.2	0.7	-1.1
Impedance of arm (right)	0.4	2.0	2.8	-1.7	1.1
Falls in the last year	0.4	0.5	1.0	0.2	-1.0
Comparative body size at age 10	0.4	1.1	1.1	1.0	1.0
Pulse wave peak to peak time	0.4	0.4	0.8	0.9	0.4
Hypertension (Self-reported)	0.4	1.1	2.0	1.4	0.4
Smoking status: Previous	0.4	0.6	0.7	0.7	0.8
Supplements: Fish oil (including cod liver oil)	0.4	0.5	0.6	-0.8	0.6
Alcohol drinker status: Previous	0.4	0.4	0.8	-0.2	0.9
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.3	-1.1	0.7
Crohns Disease (2017)	0.3	0.7	0.9	-0.9	0.8
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.3	0.1	1.1
Mean Putamen Volume	0.3	0.4	0.6	0.4	-0.8
HDL Cholesterol	0.3	0.4	0.6	0.7	0.6
LDL Cholesterol	0.3	0.5	0.9	1.0	0.3
Schizophrenia (2014)	0.3	0.6	0.6	-0.7	0.8
Triglycerides	0.3	0.5	0.7	0.8	0.5
Blood Platelet Count	0.3	2.9	3.8	1.4	1.9
Impedance of leg (right)	0.3	1.2	1.4	-1.0	1.2
Current tobacco smoking	0.3	0.5	0.8	-0.4	-0.9
Stomach or abdominal pain in last month	0.3	0.4	0.6	0.4	0.8
Forced vital capacity (FVC)	0.3	1.0	1.5	1.2	0.7
Financial difficulties in last 2 years	0.3	0.4	0.8	0.9	-0.1
Hair/balding pattern: Pattern 4	0.3	0.7	1.2	0.4	1.1
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.6	0.2	0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.6	-0.8	-0.4
Medication: Amlodipine	0.3	0.4	0.7	0.9	0.2
Supplements: Vitamin C	0.3	0.3	0.5	-0.7	-0.4
Illnesses of father: Heart disease	0.3	0.5	0.9	0.9	0.2
Diabetes diagnosed by doctor	0.3	0.4	0.8	-0.1	0.9
Commuting to job workplace: Walk	0.3	0.3	0.4	-0.6	-0.5
Mineral and other dietary supplements	0.3	0.4	0.8	0.9	0.1
Irritability	0.3	0.6	0.9	0.5	0.9
Basal cell carcinoma (self-reported)	0.3	0.4	0.6	0.7	-0.4
Fasting Glucose	0.2	0.3	0.5	0.7	0.3
Heel T-Score	0.2	1.7	3.1	-0.6	-1.8
Hand grip strength (left)	0.2	0.6	1.1	0.3	1.1
Relative age of first facial hair	0.2	0.5	0.6	-0.8	0.6
Pack years adult smoking proportion	0.2	0.3	0.4	-0.3	-0.6
Hand grip strength (right)	0.2	0.5	1.0	-0.1	1.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.3	0.5	-0.4
Sitting height	0.2	1.4	2.6	0.5	-1.6
Qualifications: None of the above	0.2	0.4	0.8	-0.9	-0.1
Medication: Simvastatin	0.2	0.3	0.5	0.7	0.3
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.9	-0.3	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.3	-0.5	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.6	-0.8	0.2
Forced vital capacity (FVC), Best measure	0.2	0.8	1.3	1.2	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.6	-0.7	-0.1
Overall health rating	0.2	0.4	0.8	-0.9	-0.0
Had major operations	0.2	0.2	0.4	-0.6	-0.1
Eye problems/disorders: Cataract	0.2	0.2	0.3	0.6	0.3
Ever smoked	0.2	0.4	0.5	-0.6	-0.7
Commuting to job workplace: Cycle	0.2	0.3	0.3	-0.6	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.5	0.5	-0.7	-0.6
Body Mass Index (BMI) (2010)	0.1	0.2	0.2	-0.3	0.5
Blood Red Count	0.1	0.9	1.8	-1.3	-0.0
Waist Hip Ratio (WHR)	0.1	0.5	0.9	-0.9	0.2
Cardiovascular Disease	0.1	0.4	0.6	0.8	0.3
Number of treatments/medications taken	0.1	0.1	0.2	-0.1	0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	0.5	-0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	0.5	-0.1
Systolic blood pressure, automated reading	0.1	0.2	0.4	0.3	0.6
Vitamin and mineral supplements	0.1	0.1	0.2	-0.4	-0.1
Medication: Metformin	0.1	0.2	0.3	0.6	0.1
Maternal smoking around birth	0.1	0.1	0.1	0.2	0.4
Past tobacco smoking	0.1	0.1	0.1	-0.4	-0.3
Diabetes (self-reported)	0.1	0.1	0.3	-0.0	0.5
Time employed in main current job	0.1	0.1	0.2	-0.4	0.3
Prospective memory result	0.1	0.1	0.2	0.4	0.4
Standing height	0.1	1.2	2.2	0.5	-1.5
Length of working week for main job	0.1	0.1	0.3	0.5	-0.2
Blood clot in the leg (DVT)	0.1	0.1	0.2	-0.4	-0.1
Shortness of breath walking on level ground	0.1	0.1	0.2	0.3	0.4
Alcohol intake frequency.	0.1	0.3	0.5	-0.3	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.2	0.5	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.1	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.6	0.0	-0.8
Qualifications: nursing, teaching	0.1	0.2	0.2	0.3	-0.5
Guilty feelings	0.1	0.2	0.4	0.1	-0.7
Medication: Bendroflumethiazide	0.1	0.1	0.2	0.4	0.1
Medication: Atorvastatin	0.1	0.1	0.3	0.5	0.0
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.1	0.4	-0.3
Pack years of smoking	0.1	0.1	0.1	0.1	-0.4
Breast Cancer	0.0	0.1	0.1	0.3	0.1
Crohns Disease (2012)	0.0	0.0	0.1	-0.3	0.0
Height	0.0	0.3	0.4	0.5	-0.7
Systolic Blood Pressure	0.0	0.1	0.3	0.1	-0.5
Smoking Status	0.0	0.0	0.0	0.2	0.2
Hair Pigment	0.0	1.4	2.8	0.2	1.7
Diabetes (mother)	0.0	0.0	0.1	0.2	-0.2
Qualifications: CSEs or equivalent	0.0	0.1	0.1	-0.1	-0.3
High blood pressure	0.0	0.1	0.1	0.4	0.2
Illnesses of siblings	0.0	0.0	0.0	0.2	-0.2
Alcohol intake versus 10 years previously	0.0	0.0	0.0	0.1	0.0
High blood pressure (siblings)	0.0	0.0	0.0	-0.0	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.1	0.1	-0.2	-0.3
Comparative height size at age 10	0.0	0.1	0.3	-0.1	-0.5
Hearing aid user	0.0	0.0	0.1	-0.2	0.1
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.0	0.2
Diastolic blood pressure, automated reading	0.0	0.0	0.0	-0.2	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.0	-0.1	0.2

Hub : Genes

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Trait associations