[Hub]/) : Traits : Pain experienced in last month :

chr3:48,702,606-50,636,111

Best TWAS P=1.52e-08 · Best GWAS P=3.19e-07 conditioned to 0.0132

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RNF123 0.19 0.18 enet 29 0.18 2.1e-14 -4.6 -5.2 1.7e-07 0.77 0.16 0.82 FALSE
2 GTEx Artery Tibial IP6K1 0.03 0.00 enet 22 0.01 2.5e-02 -4.9 -5.3 1.5e-07 0.70 0.09 0.60 FALSE
3 GTEx Brain Cerebellum MST1R 0.19 0.24 enet 22 0.20 1.8e-06 4.3 -5.1 2.9e-07 0.83 0.12 0.85 FALSE
4 GTEx Brain Cerebellum GPX1 0.31 0.09 enet 19 0.23 2.0e-07 4.8 -5.4 7.8e-08 0.43 0.04 0.94 FALSE
5 GTEx Brain Frontal Cortex BA9 GPX1 0.16 0.06 lasso 6 0.15 7.9e-05 -4.0 -5.6 2.3e-08 0.38 0.06 0.77 FALSE
6 GTEx Esophagus Muscularis GPX1 0.13 0.05 lasso 14 0.06 1.1e-04 4.8 -5.5 3.3e-08 0.40 0.04 0.94 FALSE
7 GTEx Heart Left Ventricle DAG1 0.06 0.02 enet 14 0.02 3.2e-02 -3.8 5.2 2.6e-07 -0.63 0.25 0.28 FALSE
8 GTEx Lung GPX1 0.04 0.02 enet 13 0.04 5.7e-04 4.7 -5.7 1.5e-08 0.53 0.06 0.71 TRUE
9 METSIM Adipose MST1R 0.03 0.02 blup 331 0.02 1.7e-03 -4.8 -5.5 3.9e-08 0.88 0.05 0.94 FALSE
10 ROSMAP Brain Pre-frontal Cortex MST1R 0.02 0.00 blup 278 0.01 4.5e-02 -4.8 -5.3 1.2e-07 0.81 0.12 0.80 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma AMIGO3 0.01 0.00 enet 13 0.01 5.7e-03 -3.8 -5.2 1.8e-07 0.57 0.01 0.27 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma AMIGO3 0.02 0.00 blup 40 0.00 3.0e-01 -4.6 -5.1 3.1e-07 0.70 0.01 0.60 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma UBA7 0.03 0.01 blup 30 0.02 2.0e-03 -4.5 5.2 2.3e-07 -0.79 0.02 0.66 FALSE