[Hub]/) : Traits : Knee pain experienced in last month : ←

chr20:32,865,844-34,980,465

Best TWAS P=4.53e-16 · Best GWAS P=3.99e-18 conditioned to 0.000762

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	UQCC	0.07	0.04	lasso	2	0.05	1.4e-06	-7.6	7.6	2.4e-14	-0.88	0.14	0.86	FALSE
2	GTEx	Adipose Subcutaneous	UQCC1	0.09	0.12	lasso	2	0.11	4.5e-09	-7.8	7.9	3.9e-15	-0.90	0.56	0.44	FALSE
3	GTEx	Adipose Visceral Omentum	UQCC1	0.15	0.08	lasso	7	0.07	1.6e-04	-7.8	7.5	4.4e-14	-0.87	0.38	0.50	FALSE
4	GTEx	Adrenal Gland	MMP24-AS1	0.18	0.04	enet	10	0.13	2.2e-05	-6.8	6.2	6.8e-10	-0.74	0.21	0.21	FALSE
5	GTEx	Brain Cerebellar Hemisphere	CEP250	0.51	0.40	lasso	12	0.36	4.7e-10	-5.8	5.7	1.1e-08	-0.58	0.99	0.01	FALSE
6	GTEx	Brain Cerebellar Hemisphere	RP3-477O4.14	0.15	0.13	lasso	5	0.11	9.2e-04	-5.8	5.3	9.8e-08	-0.59	0.14	0.16	FALSE
7	GTEx	Brain Cerebellum	CEP250	0.39	0.16	enet	28	0.24	8.8e-08	-6.7	5.9	3.3e-09	-0.62	0.98	0.01	FALSE
8	GTEx	Brain Cerebellum	RPL36P4	0.64	0.35	lasso	6	0.35	3.8e-11	-4.4	-5.4	7.6e-08	0.55	0.98	0.02	FALSE
9	GTEx	Brain Cortex	ERGIC3	0.15	-0.01	lasso	6	0.00	2.8e-01	-4.1	-6.4	1.7e-10	0.68	0.12	0.10	FALSE
10	GTEx	Brain Cortex	CEP250	0.14	0.16	enet	13	0.15	4.9e-05	-6.8	6.5	7.1e-11	-0.64	0.52	0.23	FALSE
11	GTEx	Brain Frontal Cortex BA9	UQCC1	0.16	0.07	lasso	3	0.08	3.7e-03	-7.6	6.9	5.9e-12	-0.80	0.08	0.38	FALSE
12	GTEx	Brain Frontal Cortex BA9	CEP250	0.47	0.18	lasso	3	0.07	6.0e-03	-5.8	5.2	2.0e-07	-0.53	0.57	0.13	FALSE
13	GTEx	Brain Hypothalamus	CEP250	0.18	-0.01	lasso	9	0.00	3.4e-01	-5.8	6.2	6.3e-10	-0.62	0.11	0.17	FALSE
14	GTEx	Brain Nucleus accumbens basal ganglia	CEP250	0.15	0.09	lasso	2	0.05	2.1e-02	-5.8	5.8	6.1e-09	-0.59	0.19	0.24	FALSE
15	GTEx	Breast Mammary Tissue (Male)	UQCC1	0.06	0.04	lasso	1	0.02	1.4e-01	-7.8	7.8	9.0e-15	-0.90	0.04	0.13	FALSE
16	GTEx	Cells Transformed fibroblasts	EDEM2	0.08	0.02	lasso	5	0.03	1.8e-03	-3.0	6.5	7.1e-11	-0.67	0.39	0.20	FALSE
17	GTEx	Cells Transformed fibroblasts	UQCC1	0.23	0.24	lasso	8	0.25	9.4e-19	-7.8	7.5	5.6e-14	-0.88	0.63	0.37	FALSE
18	GTEx	Esophagus Mucosa	UQCC1	0.13	0.10	enet	10	0.07	1.1e-05	-7.8	7.7	1.3e-14	-0.89	0.36	0.64	FALSE
19	GTEx	Esophagus Mucosa	CEP250	0.29	0.00	lasso	9	0.00	5.3e-01	-1.3	-5.6	2.7e-08	0.61	0.06	0.27	FALSE
20	GTEx	Lung	UQCC1	0.13	0.08	lasso	5	0.06	1.0e-05	-7.8	7.8	7.0e-15	-0.90	0.37	0.63	FALSE
21	GTEx	Muscle Skeletal	UQCC1	0.10	0.04	enet	19	0.05	1.3e-05	-6.6	7.5	4.6e-14	-0.79	0.58	0.40	FALSE
22	GTEx	Muscle Skeletal	CEP250	0.09	0.04	lasso	9	0.07	3.6e-07	-6.7	7.5	5.0e-14	-0.79	0.96	0.03	FALSE
23	GTEx	Muscle Skeletal	NFS1	0.03	0.02	lasso	3	0.03	1.0e-03	-3.9	-5.7	1.6e-08	0.66	0.17	0.59	FALSE
24	GTEx	Nerve Tibial	UQCC1	0.07	0.04	enet	6	0.03	2.7e-03	-7.8	7.7	1.7e-14	-0.88	0.20	0.76	FALSE
25	GTEx	Pancreas	MYH7B	0.24	0.00	enet	17	0.04	1.0e-02	-2.6	-5.5	4.8e-08	0.44	0.08	0.09	FALSE
26	GTEx	Skin Sun Exposed Lower leg	UQCC1	0.19	0.13	enet	16	0.10	8.1e-09	-7.8	7.0	2.6e-12	-0.84	0.55	0.45	FALSE
27	GTEx	Stomach	UQCC1	0.09	0.14	lasso	2	0.15	1.9e-07	-7.8	7.4	1.0e-13	-0.86	0.35	0.54	FALSE
28	METSIM	Adipose	RP3-477O4.16	0.07	0.08	lasso	3	0.07	1.6e-10	-6.7	-6.8	9.6e-12	0.63	1.00	0.00	FALSE
29	METSIM	Adipose	UQCC1	0.09	0.04	enet	18	0.05	1.5e-07	-7.8	7.5	4.6e-14	-0.90	0.13	0.87	FALSE
30	NTR	Blood	UQCC	0.01	0.01	enet	6	0.00	1.6e-02	-7.8	8.1	6.7e-16	-0.89	0.08	0.79	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	UQCC1	0.05	0.05	lasso	5	0.06	1.7e-08	-7.9	7.1	1.7e-12	-0.84	0.18	0.82	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	GDF5	0.10	0.13	lasso	2	0.12	2.9e-15	-7.8	-7.8	5.1e-15	0.90	0.50	0.50	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	CEP250	0.15	0.14	lasso	5	0.13	2.3e-16	-6.8	6.8	1.4e-11	-0.64	1.00	0.00	FALSE
34	YFS	Blood	CEP250	0.15	0.12	lasso	13	0.13	9.2e-41	-6.8	6.2	4.6e-10	-0.63	1.00	0.00	FALSE
35	YFS	Blood	PROCR	0.01	0.00	blup	348	0.01	3.3e-03	-4.4	5.7	1.6e-08	-0.70	0.08	0.75	FALSE
36	YFS	Blood	UQCC	0.21	0.19	lasso	26	0.20	6.4e-64	-7.8	7.2	6.9e-13	-0.88	0.53	0.47	FALSE
37	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UQCC	0.03	0.04	blup	67	0.03	2.6e-03	-7.8	8.0	8.9e-16	-0.91	0.02	0.91	FALSE
38	The Cancer Genome Atlas	Breast Invasive Carcinoma	CEP250	0.01	0.02	blup	43	0.02	5.8e-05	-6.8	-6.3	3.0e-10	0.59	0.89	0.01	FALSE
39	The Cancer Genome Atlas	Breast Invasive Carcinoma	ERGIC3	0.01	0.00	blup	39	0.01	2.3e-02	-4.1	5.5	4.0e-08	-0.51	0.02	0.40	FALSE
40	The Cancer Genome Atlas	Breast Invasive Carcinoma	UQCC	0.08	0.11	blup	67	0.12	1.1e-22	-7.8	7.7	1.8e-14	-0.89	0.59	0.41	FALSE
41	The Cancer Genome Atlas	Colon Adenocarcinoma	ERGIC3	0.05	0.03	blup	39	0.04	3.0e-03	-4.9	5.9	3.9e-09	-0.61	0.02	0.86	FALSE
42	The Cancer Genome Atlas	Glioblastoma Multiforme	UQCC	0.15	0.02	blup	67	0.04	2.0e-02	-2.2	6.2	6.2e-10	-0.74	0.02	0.64	FALSE
43	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CEP250	0.02	0.01	blup	43	0.02	8.0e-04	-6.7	-7.7	1.2e-14	0.79	0.03	0.82	FALSE
44	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UQCC	0.05	0.06	blup	66	0.06	3.6e-07	-6.8	7.4	1.8e-13	-0.87	0.12	0.88	FALSE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEP250	0.03	0.01	blup	43	0.03	2.6e-04	-8.7	-7.5	4.4e-14	0.77	0.01	0.89	FALSE
46	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UQCC	0.09	0.10	blup	67	0.10	7.2e-11	-7.5	7.6	2.1e-14	-0.88	0.66	0.34	FALSE
47	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UQCC	0.08	0.01	lasso	3	0.01	9.0e-02	-6.6	5.7	9.5e-09	-0.72	0.04	0.85	FALSE
48	The Cancer Genome Atlas	Brain Lower Grade Glioma	GDF5	0.09	0.11	blup	76	0.12	1.0e-13	-7.5	-7.1	1.7e-12	0.83	0.13	0.87	FALSE
49	The Cancer Genome Atlas	Brain Lower Grade Glioma	UQCC	0.04	0.06	lasso	6	0.05	2.3e-06	-7.8	7.8	5.1e-15	-0.90	0.43	0.57	FALSE
50	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CEP250	0.09	0.06	lasso	4	0.06	1.2e-03	-5.8	-6.3	3.9e-10	0.60	0.51	0.18	FALSE
51	The Cancer Genome Atlas	Lung Adenocarcinoma	CEP250	0.02	0.02	blup	43	0.02	4.0e-03	-6.8	-6.2	6.0e-10	0.57	0.26	0.05	FALSE
52	The Cancer Genome Atlas	Lung Adenocarcinoma	ERGIC3	0.04	0.03	blup	39	0.03	9.3e-05	-4.1	5.5	5.0e-08	-0.50	0.04	0.93	FALSE
53	The Cancer Genome Atlas	Lung Adenocarcinoma	UQCC	0.10	0.07	enet	10	0.07	1.5e-08	-7.9	7.6	3.6e-14	-0.89	0.08	0.92	FALSE
54	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UQCC	0.07	0.08	blup	67	0.07	1.1e-08	-7.5	6.9	5.4e-12	-0.82	0.05	0.95	FALSE
55	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	GDF5	0.05	0.02	blup	76	0.04	1.4e-03	-7.8	-7.7	9.6e-15	0.89	0.03	0.91	FALSE
56	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	UQCC	0.12	0.03	blup	67	0.09	1.7e-04	-7.5	7.6	2.3e-14	-0.83	0.02	0.89	FALSE
57	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UQCC	0.22	0.21	lasso	7	0.18	1.9e-07	-7.5	7.5	4.9e-14	-0.84	0.27	0.73	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	CEP250	0.08	0.15	enet	16	0.15	3.1e-15	-6.8	-6.9	6.9e-12	0.63	1.00	0.00	FALSE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	FAM83C	0.16	0.10	lasso	4	0.11	2.1e-11	-5.8	5.5	3.8e-08	-0.58	1.00	0.00	FALSE
60	The Cancer Genome Atlas	Prostate Adenocarcinoma	GDF5	0.05	0.05	lasso	5	0.04	7.2e-05	-8.7	-8.1	7.4e-16	0.95	0.00	1.00	FALSE
61	The Cancer Genome Atlas	Prostate Adenocarcinoma	UQCC	0.07	0.10	lasso	8	0.11	1.3e-11	-7.5	7.8	9.3e-15	-0.90	0.30	0.70	FALSE
62	The Cancer Genome Atlas	Soft Tissue Sarcoma	UQCC	0.07	0.06	blup	66	0.07	5.2e-05	-7.8	7.7	1.2e-14	-0.89	0.02	0.97	FALSE
63	The Cancer Genome Atlas	Stomach Adenocarcinoma	GDF5	0.09	0.04	enet	13	0.05	2.4e-04	-8.7	-8.1	4.8e-16	0.85	0.00	0.99	TRUE
64	The Cancer Genome Atlas	Stomach Adenocarcinoma	UQCC	0.07	0.06	lasso	10	0.06	2.8e-05	-7.6	7.7	1.5e-14	-0.88	0.04	0.95	FALSE
65	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CEP250	0.10	0.00	blup	43	0.05	9.8e-03	-6.6	-7.2	6.4e-13	0.73	0.01	0.24	FALSE
66	The Cancer Genome Atlas	Thyroid Carcinoma	CEP250	0.05	0.03	blup	43	0.04	5.8e-05	-6.8	-7.7	1.4e-14	0.78	0.12	0.83	FALSE
67	The Cancer Genome Atlas	Thyroid Carcinoma	GDF5	0.02	0.00	blup	76	0.00	1.9e-01	-7.8	-8.1	4.5e-16	0.90	0.02	0.88	FALSE
68	The Cancer Genome Atlas	Thyroid Carcinoma	UQCC	0.15	0.21	blup	67	0.22	1.2e-20	-7.8	7.7	2.0e-14	-0.88	0.39	0.61	FALSE
69	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	UQCC	0.13	0.15	lasso	1	0.11	7.1e-04	-6.5	6.5	8.2e-11	-0.74	0.04	0.65	FALSE