TWAS hub - KIAA0892

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Brain Lower Grade Glioma	0.0272	0.023	0.00430	0.013	0.015	0.013	NA	0.015	1.1e-02	0.0074	0.011	NA	0.0064
2	TCGA	Thyroid Carcinoma	0.0370	0.025	0.00043	0.044	0.020	0.010	NA	0.019	3.6e-05	0.0041	0.033	NA	0.0050

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
High cholesterol (Self-reported)	20.7	36.7	38.4	5.9	6.2
Medication: Cholesterol lowering	17.3	26.9	28.4	5.0	5.3
Triglycerides	16.1	26.3	29.6	4.8	5.4
Breast Cancer	15.1	36.3	37.6	6.1	5.9
Blood Platelet Count	13.8	160.1	166.4	-12.4	-12.9
Sensitivity / hurt feelings	11.8	20.2	20.5	-4.5	-4.5
Schizophrenia (2014)	11.4	25.2	31.8	-4.3	-5.6
Medication: Simvastatin	11.2	16.5	17.1	4.0	4.1
Impedance of leg (right)	11.1	53.6	54.6	-7.4	-7.2
Impedance of leg (left)	11.1	53.9	55.4	-7.4	-7.2
Comparative body size at age 10	10.5	29.0	30.5	5.5	5.2
Medication: Atorvastatin	9.3	11.5	12.9	3.2	3.6
Rheumatoid Arthritis	9.1	12.5	14.1	-3.3	-3.8
Illnesses of siblings: Diabetes	8.7	10.7	11.5	-3.4	-3.1
Schizophrenia (2018)	8.4	17.5	21.9	-3.6	-4.7
Illnesses of father: Heart disease	8.4	11.7	11.9	3.4	3.5
Hearing difficulty/problems: Yes	8.0	12.2	12.6	3.6	3.4
Myopia	7.8	11.3	12.0	-3.2	-3.5
Bipolar Disorder or Schizophrenia	7.7	18.8	23.4	-3.8	-4.8
Diabetes (mother)	7.6	9.7	11.0	-3.3	-2.9
Age at first live birth	7.4	13.1	14.0	3.7	3.5
Mother’s age at death	7.4	9.2	10.6	3.3	2.8
Serious illness, injury or assault of a close relative in last 2 years	7.2	8.3	9.3	2.7	3.0
Townsend deprivation index at recruitment	7.0	9.8	10.2	3.2	3.1
Mouth/teeth dental problems: Mouth ulcers	6.8	10.8	10.8	-3.3	-3.3
Taking other prescription medications	6.1	9.5	10.4	-3.2	-2.9
LDL Cholesterol	6.0	9.5	11.0	2.9	3.3
Impedance of whole body	5.9	29.9	31.1	-5.6	-5.4
Vitamin and mineral supplements	5.8	7.8	8.1	2.8	2.8
Maternal smoking around birth	5.7	8.3	8.5	-2.9	-2.9
Leg fat-free mass (right)	5.5	29.4	29.5	5.4	5.4
Leg predicted mass (right)	5.5	29.4	29.5	5.4	5.4
Blood Eosinophil Count	5.4	41.6	42.2	-6.4	-6.5
Ovarian Cancer	5.3	7.1	7.3	2.7	2.6
Fasting Glucose	4.9	5.9	6.7	-2.3	-2.6
Stomach or abdominal pain in last month	4.8	6.0	6.1	-2.5	-2.4
Body Mass Index (BMI) (2010)	4.7	6.5	6.7	2.6	2.5
Leg fat-free mass (left)	4.6	24.5	24.6	4.9	5.0
Leg predicted mass (left)	4.6	24.5	24.6	4.9	5.0
Hair/balding pattern: Pattern 2	4.6	5.9	6.5	-2.6	-2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.5	5.3	5.4	-2.3	-2.3
Financial situation satisfaction	4.5	5.5	5.7	2.4	2.3
Neuroticism (Nagel 2018)	4.4	10.3	11.7	-3.4	-3.0
Medication: Levothyroxine sodium	4.4	7.5	7.8	-2.8	-2.7
Medication: Gliclazide	4.4	4.9	5.2	-2.2	-2.3
Pulse rate	4.3	7.3	7.8	-2.6	-2.8
Age at last live birth	4.3	6.2	6.8	2.6	2.4
Qualifications: None of the above	4.2	9.0	9.5	-2.9	-3.1
Mouth/teeth dental problems: Bleeding gums	4.2	5.5	5.6	2.4	2.3
Prospective memory result	4.1	5.0	5.2	-2.2	-2.3
Had major operations	4.1	4.7	5.1	2.3	2.1
Average weekly champagne plus white wine intake	4.0	5.5	5.7	2.4	2.3
Type 2 Diabetes (T2D) (2018)	3.9	7.4	8.1	-2.6	-2.8
Breast cancer (self-reported)	3.9	4.6	5.4	-1.9	-2.3
Whole body water mass	3.9	22.0	22.3	4.7	4.7
Supplements: Calcium	3.9	4.3	4.3	-2.0	-2.1
Medication: Paracetamol	3.8	6.3	6.5	-2.5	-2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.8	4.5	4.7	2.2	2.1
Whole body fat-free mass	3.8	21.6	21.8	4.6	4.7
Hypothyroidism/myxoedema (self-reported)	3.6	7.1	7.7	-2.8	-2.6
Irritable Bowel Disease (IBD)	3.5	8.3	8.9	-2.8	-3.0
Medication: Co-codamol	3.5	4.1	4.2	-2.0	-2.1
Qualifications: College or University degree	3.5	10.9	12.0	3.5	3.1
Risk taking	3.5	5.2	5.4	-2.2	-2.3
Type 2 Diabetes (T2D) (2012)	3.4	3.9	5.2	-1.6	-2.3
Neck or shoulder pain in last month	3.4	4.9	5.1	-2.3	-2.2
Commuting to job workplace: Cycle	3.4	4.1	4.3	2.0	2.1
Headache pain in last month	3.3	5.7	6.2	-2.3	-2.5
Commuting to job workplace: Walk	3.3	3.6	4.3	1.7	2.1
Smoking status: Current	3.3	5.2	5.2	-2.3	-2.3
Pain type(s) experienced in last month: Hip pain	3.3	4.2	5.0	-2.2	-1.8
Fluid intelligence score	3.2	6.6	7.1	2.5	2.7
Trunk fat-free mass	3.2	18.4	18.6	4.3	4.3
Worry (Nagel 2018)	3.1	6.6	6.9	-2.6	-2.5
Number of live births	3.1	4.4	4.4	-2.1	-2.1
Trunk predicted mass	3.1	17.7	17.8	4.2	4.2
Ever had stillbirth, spontaneous miscarriage or termination	3.1	3.3	3.5	-1.9	-1.8
Basal metabolic rate	3.1	17.3	17.5	4.1	4.2
Ulcerative Colitis (UC)	3.0	5.6	5.7	-2.3	-2.4
Bipolar Disorder (2011)	3.0	2.9	3.4	-1.5	-1.8
Coronary Artery Disease (CAD)	3.0	3.5	3.8	1.8	1.9
Alcohol intake versus 10 years previously	2.9	4.3	4.7	-2.2	-2.0
Medication for cholesterol, blood pressure or diabetes	2.9	4.8	5.8	-1.9	-2.4
Severe depression (siblings)	2.8	3.1	3.1	-1.8	-1.8
Current tobacco smoking	2.8	4.6	4.6	-2.2	-2.1
Medication: Ramipril	2.8	3.6	4.1	-2.0	-1.8
Illnesses of father: None of the above (group 1)	2.8	3.4	3.5	-1.8	-1.9
Frequency of depressed mood in last 2 weeks	2.7	3.7	3.9	1.9	2.0
Medication: Metformin	2.7	3.8	4.0	-2.0	-1.9
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.1	4.3	2.1	2.0
Qualifications: nursing, teaching	2.6	4.0	5.0	1.7	2.2
Crohns Disease (2017)	2.5	5.4	6.3	-2.1	-2.5
Qualifications: A levels/AS levels or equivalent	2.5	5.5	5.7	2.4	2.3
Age when periods started (menarche)	2.4	5.8	5.9	-2.4	-2.4
High blood pressure (mother)	2.4	3.4	3.5	-1.9	-1.8
Illnesses of siblings	2.4	3.3	3.7	1.9	1.7
Happiness	2.4	2.9	3.1	1.7	1.8
Guilty feelings	2.3	3.5	4.1	1.7	2.0
Eye problems/disorders: Glaucoma	2.3	2.7	2.9	1.6	1.7
Diastolic blood pressure, automated reading	2.3	7.2	8.5	-2.4	-2.9
Multivitamins +/- minerals	2.2	2.7	3.2	-1.8	-1.5
Overall health rating	2.2	4.8	5.0	-2.2	-2.1
Schizophrenia vs Biploar Disorder	2.1	2.7	3.6	-1.3	-1.9
Heel T-Score	2.1	16.7	19.1	-3.8	-4.4
Hypothyroidism (self reported)	2.1	4.8	5.3	-2.3	-2.1
Exposure to tobacco smoke at home	2.1	2.4	2.4	-1.5	-1.6
Comparative height size at age 10	2.1	11.4	12.4	3.2	3.5
Diabetes diagnosed by doctor	2.1	3.4	3.4	-1.8	-1.9
Medication: Aspirin	2.0	2.6	2.8	1.5	1.7
Ever taken oral contraceptive pill	2.0	2.2	2.3	1.5	1.5
Commuting to job workplace: Public transport	2.0	2.4	2.4	1.6	1.5
Bipolar Disorder (2018)	1.9	3.0	3.6	-1.6	-1.9
Crohns Disease (2012)	1.9	3.1	3.5	-1.6	-1.9
Birth weight of first child	1.8	3.2	4.0	1.6	2.0
Glaucoma (self-reported)	1.8	2.1	2.1	1.5	1.4
Heart disease (mother)	1.8	2.2	2.4	1.4	1.6
Number of full sisters	1.8	2.2	2.3	-1.5	-1.5
Average weekly spirits intake	1.7	2.0	2.2	-1.4	-1.5
Falls in the last year	1.7	2.2	2.3	-1.5	-1.5
Pulse wave Arterial Stiffness index	1.7	2.0	2.0	-1.4	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	2.1	-1.5	-1.4
Pulse wave peak to peak time	1.7	2.0	2.1	1.4	1.4
Depressed Affect (Nagel 2018)	1.6	3.3	4.3	-2.1	-1.5
Angina	1.6	2.1	2.3	1.5	1.4
Illnesses of mother	1.6	2.0	2.2	1.5	1.3
Arm fat-free mass (right)	1.6	8.0	8.5	2.8	2.9
Mouth/teeth dental problems: Loose teeth	1.6	1.9	2.1	-1.4	-1.3
Arm predicted mass (right)	1.6	8.2	8.6	2.8	2.9
Back pain experienced in last month	1.6	2.3	3.0	1.3	1.7
Medication: Paracetamol	1.6	2.5	2.6	-1.6	-1.6
Nervous feelings	1.5	2.8	3.0	-1.7	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	2.5	-1.6	-1.5
Angina (self-reported)	1.5	2.0	2.1	1.4	1.4
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	2.4	-1.1	-1.6
Neuroticism	1.4	3.4	4.2	-2.0	-1.6
Diabetes (self-reported)	1.4	2.1	2.2	-1.4	-1.5
Hair/balding pattern: Pattern 3	1.4	2.1	2.2	1.5	1.4
Birth weight	1.4	3.0	3.3	1.6	1.8
Supplements: Vitamin C	1.4	1.7	1.8	-1.3	-1.3
Ever had bowel cancer screening	1.4	1.7	1.9	-1.2	-1.4
Arm fat-free mass (left)	1.4	7.0	7.3	2.6	2.7
Pain experienced in last month	1.4	2.4	2.9	1.7	1.3
Heart disease (siblings)	1.4	1.7	2.1	1.1	1.5
Arm predicted mass (left)	1.4	6.9	7.1	2.6	2.7
Alzheimer’s Disease (including proxy)	1.3	1.8	2.0	-1.4	-1.3
Ulcerative Colitis	1.3	1.9	2.2	-1.3	-1.5
Cardiovascular Disease	1.3	4.3	4.9	2.0	2.2
Weight	1.3	6.2	6.2	2.5	2.5
Leg fat percentage (right)	1.3	4.7	4.8	-2.1	-2.2
Medication: Allopurinol	1.3	1.7	2.1	-1.5	-1.1
Pulse rate, automated reading	1.3	4.1	4.8	-1.9	-2.2
Medication: Aspirin	1.3	1.6	1.8	1.2	1.3
Commuting to job workplace: Car/motor vehicle	1.2	1.4	1.4	-1.2	-1.2
Tinnitus: Yes, now most or all of the time	1.2	1.4	1.5	-1.2	-1.1
Major Depression (MDD)	1.1	1.3	1.5	1.1	1.2
Number of treatments/medications taken	1.1	1.9	2.6	-1.6	-1.1
Peak expiratory flow (PEF)	1.1	2.6	3.2	1.4	1.8
Medication: Blood pressure	1.1	2.0	2.1	-1.4	-1.4
Leg fat percentage (left)	1.1	3.9	3.9	-1.9	-2.0
Average weekly beer plus cider intake	1.1	1.5	1.7	-1.3	-1.2
Blood White Count	1.0	7.2	7.3	-2.7	-2.6
Lung cancer (father)	1.0	1.2	1.3	-1.2	-1.0
Medication: Amlodipine	1.0	1.5	1.8	1.0	1.4
Average weekly red wine intake	1.0	1.5	1.6	-1.3	-1.2
Fractured/broken bones in last 5 years	1.0	1.4	1.6	1.1	1.3
Reaction Time	0.9	1.7	2.2	1.5	1.1
Fed-up feelings	0.9	1.7	2.0	-1.4	-1.2
Waist circumference	0.9	3.5	3.6	1.8	1.9
Hearing difficulty/problems with background noise	0.9	1.5	1.7	1.3	1.1
Medication: Lansoprazole	0.9	1.0	1.2	-1.1	-0.9
Impedance of arm (left)	0.9	4.3	4.7	-2.2	-2.0
Suffer from ‘nerves’	0.9	1.4	1.4	-1.2	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	1.4	-0.9	-1.2
Medication: Bendroflumethiazide	0.9	1.4	1.6	-1.2	-1.1
Basal cell carcinoma (self-reported)	0.9	1.1	1.2	-1.1	-1.0
Alcohol drinker status: Previous	0.9	1.1	1.2	-1.1	-1.0
Alzheimer’s Disease (in mother)	0.8	1.0	1.0	-1.0	-1.0
BMI	0.8	4.4	4.9	2.2	2.0
Smoking Status	0.8	1.8	2.0	-1.4	-1.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.0	-1.0	-0.9
Pack years adult smoking proportion	0.8	1.2	1.4	-1.0	-1.2
Had other major operations	0.8	1.0	1.0	-1.0	-0.9
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	1.3	0.8	1.2
Impedance of arm (right)	0.8	3.9	4.0	-2.0	-2.0
Worrier / anxious feelings	0.8	1.5	1.8	-1.1	-1.3
Tense / ‘highly strung’	0.8	1.3	1.6	-1.3	-1.0
Gout (self-reported)	0.8	1.0	1.4	-1.2	-0.8
Eye problems/disorders: None of the above	0.8	1.0	1.1	1.0	0.9
Mean time to correctly identify matches	0.8	1.5	1.7	1.3	1.2
Alcohol intake frequency.	0.8	1.9	2.3	-1.2	-1.5
Age started oral contraceptive pill	0.8	1.0	1.0	-1.0	-0.9
Intelligence (Savage-Jansen 2018)	0.7	2.3	2.4	1.6	1.4
Systolic Blood Pressure	0.7	3.6	4.1	-1.8	-2.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.1	0.9	1.0
High blood pressure (siblings)	0.7	1.0	1.2	-1.1	-0.9
Medication: Ibuprofen	0.7	0.8	1.0	-0.8	-1.0
Medication for cholesterol	0.7	1.1	1.2	1.1	1.0
Supplements: Fish oil (including cod liver oil)	0.7	1.0	1.3	0.8	1.1
Cholesterol lowering medication	0.7	1.1	1.5	0.8	1.2
Verbal and Numeric Reasoning (VNR)	0.6	1.4	1.5	1.2	1.2
Pain all over the body in last month	0.6	0.6	0.6	-0.8	-0.8
Arm fat mass (right)	0.6	2.6	2.6	1.6	1.6
Standing height	0.6	5.9	6.7	2.3	2.6
Number of children fathered	0.6	0.7	0.9	-0.7	-1.0
Eye problems/disorders: Cataract	0.6	0.7	0.9	-0.8	-0.9
Mineral and other dietary supplements	0.6	0.9	1.1	-0.8	-1.0
Osteoarthritis (self-reported)	0.6	0.8	1.0	-1.0	-0.8
Arm fat mass (left)	0.6	2.6	2.7	1.6	1.6
Unable to work because of sickness or disability	0.6	0.8	1.2	-1.1	-0.7
Age at First Birth	0.5	0.8	1.2	1.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.1	-1.1	-1.1
Hayfever, allergic rhinitis or eczema	0.5	1.1	1.1	1.1	1.1
Chronic bronchitis/emphysema (father)	0.5	0.5	0.8	0.5	0.9
Body mass index (BMI)	0.5	2.2	2.4	1.5	1.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	0.9	0.6	1.0
Time employed in main current job	0.5	0.6	0.7	-0.8	-0.8
Asthma	0.5	0.9	1.0	1.0	0.9
Forced vital capacity (FVC), Best measure	0.5	1.7	2.4	1.0	1.5
Loneliness, isolation	0.5	0.7	1.0	-1.0	-0.7
Hearing aid user	0.5	0.5	0.9	0.5	0.9
Medication: Lisinopril	0.5	0.7	0.8	0.7	0.9
Ever smoked	0.5	0.9	1.2	0.7	1.1
Pack years of smoking	0.5	0.7	0.8	-0.7	-0.9
Chronotype (morning person)	0.4	0.9	0.9	0.9	1.0
Relative age of first facial hair	0.4	0.8	1.2	-1.1	-0.6
Systolic blood pressure, automated reading	0.4	1.2	1.6	-0.9	-1.2
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	0.6	0.6	0.8
Forced vital capacity (FVC)	0.4	1.6	2.0	1.1	1.4
Financial difficulties in last 2 years	0.4	0.6	0.8	0.6	0.9
Hip circumference	0.4	1.9	2.0	1.4	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	1.8	0.9	1.4
Pulse wave reflection index	0.4	0.5	0.5	0.7	0.7
Worry too long after embarrassment	0.4	0.8	0.9	-0.9	-0.8
Medication for pain relief, constipation, heartburn	0.4	0.7	0.9	0.9	0.6
Medication: Omeprazole	0.4	0.5	0.6	0.8	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.2	-1.1	-0.7
Handedness (chirality/laterality): Left-handed	0.4	0.4	0.7	0.5	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	0.9	0.8	1.0
Number of self-reported non-cancer illnesses	0.4	0.6	1.1	-1.1	-0.4
Wears glasses or contact lenses	0.4	0.4	0.5	-0.7	-0.6
Alcohol drinker status: Never	0.4	0.5	0.6	0.7	0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	0.6	0.7	0.6
Alzheimer’s Disease (in father)	0.3	0.3	0.5	-0.7	-0.3
Mean Putamen Volume	0.3	0.3	0.4	-0.5	-0.6
Diabetes (father)	0.3	0.4	0.7	-0.3	-0.8
Hand grip strength (right)	0.3	0.9	1.2	1.1	0.8
Qualifications: CSEs or equivalent	0.3	0.4	0.5	-0.6	-0.7
Number of incorrect matches in round	0.3	0.5	0.6	-0.6	-0.8
Allergy	0.3	0.7	0.8	-0.9	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.5	-0.6	-0.7
Hair/balding pattern: Pattern 4	0.3	0.6	0.9	1.0	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.4	-0.7	-0.6
Number of full brothers	0.3	0.3	0.4	-0.6	-0.6
Wheeze or whistling in the chest in last year	0.3	0.6	1.0	-1.0	-0.5
Health satisfaction	0.3	0.4	0.4	0.6	0.6
Knee pain experienced in last month	0.3	0.4	0.7	-0.9	-0.2
Asthma (self-reported)	0.3	0.6	0.7	0.8	0.8
Ever depressed for a whole week	0.3	0.4	0.6	0.4	0.7
Depression (Nagel 2018)	0.2	0.3	0.3	0.5	0.6
Neuroticism (2016)	0.2	0.3	0.3	-0.5	-0.5
Blood Red Count	0.2	1.8	2.2	1.5	1.2
Allergy or Eczema	0.2	0.5	0.6	0.8	0.5
Hand grip strength (left)	0.2	0.6	0.8	0.9	0.7
Ever had hysterectomy (womb removed)	0.2	0.3	0.3	-0.5	-0.5
Average weekly fortified wine intake	0.2	0.2	0.2	0.5	0.4
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	-0.5	-0.4
Supplements: Glucosamine	0.2	0.3	0.3	0.5	0.5
Alcohol usually taken with meals	0.2	0.4	0.5	-0.5	-0.7
Had menopause	0.2	0.3	0.5	0.4	0.7
Neuroticism score	0.2	0.5	0.7	-0.8	-0.6
Arm fat percentage (right)	0.2	0.8	0.8	0.9	0.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.0	0.7	1.0
Depression (self-reported)	0.2	0.3	0.4	0.4	0.7
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.4	-0.4	-0.6
Blood clot in the leg (DVT)	0.2	0.2	0.3	-0.5	-0.5
Body fat percentage	0.2	0.6	0.7	-0.8	-0.8
Whole body fat mass	0.2	0.8	0.9	0.9	1.0
Arm fat percentage (left)	0.2	0.8	0.8	0.9	0.9
Illnesses of father: High blood pressure	0.2	0.2	0.3	-0.4	-0.5
Number of operations (self-reported)	0.2	0.3	0.3	0.6	0.5
Lupus	0.1	0.2	0.2	-0.4	-0.4
Waist Hip Ratio (WHR)	0.1	0.4	0.4	0.6	0.6
Respiratory disease	0.1	0.2	0.3	0.4	0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.3	-0.5	-0.0
Medication for hormone replacement therapy	0.1	0.1	0.2	-0.3	-0.4
Supplements: Zinc	0.1	0.1	0.2	-0.2	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.1	0.3	0.1
Relative age voice broke	0.1	0.2	0.3	-0.6	-0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.4	-0.3
Trunk fat mass	0.1	0.6	0.6	0.7	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	-0.4	-0.7
Mouth/teeth dental problems	0.1	0.1	0.2	0.5	0.2
Mouth/teeth dental problems: Dentures	0.1	0.2	0.2	-0.5	-0.4
Length of working week for main job	0.1	0.1	0.2	-0.0	-0.5
Breastfed as a baby	0.1	0.1	0.1	0.4	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.1	-0.4	0.2
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	-0.4	-0.2
Exposure to tobacco smoke outside home	0.1	0.2	0.2	0.4	0.4
Shortness of breath walking on level ground	0.1	0.1	0.1	-0.3	-0.4
Emphysema/chronic bronchitis	0.1	0.1	0.2	-0.4	-0.3
Medication: Blood pressure	0.1	0.2	0.3	-0.5	-0.2
Migraine (self-reported)	0.1	0.2	0.2	0.4	0.4
Medication: Seretide 50 evohaler	0.1	0.1	0.2	0.2	0.4
Chest pain or discomfort	0.1	0.2	0.2	0.4	0.5
Hypertension (Self-reported)	0.1	0.3	0.5	-0.7	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	0.2	0.4
Smoking status: Previous	0.1	0.1	0.2	0.2	0.4
Friendships satisfaction	0.1	0.2	0.3	0.2	0.5
Miserableness	0.1	0.1	0.2	0.3	0.4
Irritability	0.1	0.2	0.3	-0.5	-0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	0.3	0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.1	-0.3	-0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
HbA1C	0.0	0.0	0.0	0.2	-0.1
HDL Cholesterol	0.0	0.0	0.1	0.1	0.3
Primary Biliary Cirrhosis	0.0	0.0	0.0	-0.2	0.0
Height	0.0	0.1	0.1	0.1	0.3
Lung FEV1/FVC ratio	0.0	0.1	0.1	-0.2	-0.4
Lung FVC	0.0	0.1	0.2	-0.4	-0.3
Hair Pigment	0.0	0.3	0.4	0.7	0.4
Tanning	0.0	0.1	0.1	0.2	0.3
Trunk fat percentage	0.0	0.1	0.2	-0.4	-0.3
Serious illness, injury or assault to yourself	0.0	0.0	0.1	0.3	0.1
High blood pressure	0.0	0.1	0.2	-0.4	-0.1
Medication: Atenolol	0.0	0.1	0.1	0.2	0.3
Sitting height	0.0	0.2	0.2	-0.4	-0.5
Past tobacco smoking	0.0	0.1	0.1	-0.0	-0.3
Heart attack	0.0	0.0	0.0	-0.1	-0.2
Father’s age at death	0.0	0.0	0.0	-0.1	-0.2
Noisy workplace	0.0	0.0	0.0	-0.0	0.1
Loud music exposure frequency	0.0	0.0	0.0	0.1	0.0
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	-0.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.1	-0.1	0.2
Leg fat mass (right)	0.0	0.0	0.0	0.1	0.1
Family relationship satisfaction	0.0	0.0	0.0	-0.0	0.2
Leg pain on walking	0.0	0.0	0.1	-0.3	0.0
Mood swings	0.0	0.1	0.1	-0.4	-0.1
Long-standing illness, disability or infirmity	0.0	0.1	0.1	-0.2	0.3
Osteoporosis (self-reported)	0.0	0.0	0.0	0.1	-0.1
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.0	0.1	-0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.0	0.2	0.1
Leg fat mass (left)	0.0	0.1	0.1	0.2	0.2

Hub : Genes

KIAA0892

Models

Trait associations