[Hub]/) : Traits : BMI : ← →

chr1:108,854,166-110,931,112

Best TWAS P=5.52e-11 · Best GWAS P=7.82e-10 conditioned to 0.00299

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	ATXN7L2	0.23	0.03	enet	12	0.11	9.1e-09	-2.6	5.1	2.8e-07	-0.49	0.07	0.90	FALSE
2	GTEx	Brain Caudate basal ganglia	AMIGO1	0.17	0.00	enet	10	0.00	4.4e-01	-6.1	5.3	1.3e-07	-0.86	0.02	0.80	FALSE
3	GTEx	Brain Cerebellar Hemisphere	ATXN7L2	0.24	-0.01	enet	9	-0.01	5.3e-01	4.0	6.5	6.0e-11	-0.61	0.04	0.23	FALSE
4	GTEx	Brain Cerebellum	SYPL2	0.16	0.02	enet	9	0.03	5.1e-02	5.6	5.7	1.4e-08	-0.65	0.08	0.78	FALSE
5	GTEx	Brain Cortex	GSTM1	0.35	0.01	enet	16	0.12	2.8e-04	1.8	5.4	5.9e-08	-0.56	0.04	0.64	FALSE
6	GTEx	Brain Cortex	AC000032.2	0.37	0.01	enet	17	0.13	2.1e-04	1.8	5.6	2.7e-08	-0.59	0.03	0.70	FALSE
7	GTEx	Cells Transformed fibroblasts	PSMA5	0.12	0.02	lasso	5	0.01	3.4e-02	3.6	-5.4	7.1e-08	0.29	0.07	0.53	FALSE
8	GTEx	Liver	SYPL2	0.34	0.27	lasso	5	0.30	4.6e-09	5.5	6.2	6.5e-10	-0.61	0.09	0.90	FALSE
9	GTEx	Liver	ATXN7L2	0.39	0.04	lasso	12	0.21	1.3e-06	5.6	5.3	1.1e-07	-0.45	0.07	0.80	FALSE
10	GTEx	Lung	AMIGO1	0.14	0.07	enet	22	0.06	3.6e-05	3.9	5.7	1.4e-08	-0.64	0.60	0.40	FALSE
11	GTEx	Muscle Skeletal	CYB561D1	0.07	0.00	lasso	3	0.00	7.2e-01	5.4	-5.4	6.3e-08	0.58	0.08	0.75	FALSE
12	GTEx	Ovary	SYPL2	0.39	0.44	lasso	5	0.46	8.8e-13	5.5	-5.6	1.7e-08	0.63	0.09	0.91	FALSE
13	GTEx	Ovary	ATXN7L2	0.18	0.18	enet	17	0.13	5.6e-04	5.4	-5.2	2.2e-07	0.60	0.10	0.80	FALSE
14	GTEx	Prostate	RP11-20O24.4	0.33	0.01	enet	30	0.13	3.2e-04	5.8	5.6	1.9e-08	-0.15	0.03	0.40	FALSE
15	GTEx	Stomach	SYPL2	0.23	0.18	lasso	8	0.21	2.3e-10	5.5	5.6	1.9e-08	-0.59	0.08	0.92	FALSE
16	GTEx	Testis	SYPL2	0.45	0.50	enet	22	0.54	5.0e-28	5.5	-5.7	1.5e-08	0.61	0.10	0.90	FALSE
17	GTEx	Testis	ATXN7L2	0.28	0.34	lasso	4	0.33	3.7e-15	5.7	-5.6	2.2e-08	0.59	0.08	0.91	FALSE
18	NTR	Blood	SORT1	0.05	0.06	lasso	6	0.06	2.1e-17	5.5	5.6	1.7e-08	-0.64	0.11	0.89	FALSE
19	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	AMIGO1	0.10	0.14	enet	10	0.11	2.8e-09	3.9	5.6	2.7e-08	-0.72	0.63	0.37	FALSE
20	The Cancer Genome Atlas	Esophageal Carcinoma	AMIGO1	0.24	0.08	blup	46	0.18	3.0e-06	4.1	6.2	4.0e-10	-0.71	0.06	0.53	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SYPL2	0.03	0.05	lasso	4	0.05	6.6e-06	5.5	5.4	5.2e-08	-0.60	0.05	0.94	FALSE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AMIGO1	0.13	0.13	blup	46	0.12	1.7e-13	3.8	5.7	1.2e-08	-0.69	0.97	0.03	FALSE
23	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MYBPHL	0.16	0.18	enet	10	0.17	2.3e-11	5.4	5.8	9.1e-09	-0.58	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AMIGO1	0.14	0.14	blup	46	0.14	1.1e-05	3.9	6.1	8.5e-10	-0.71	0.14	0.76	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	ATXN7L2	0.06	0.06	lasso	3	0.05	6.6e-06	5.4	-5.5	4.2e-08	0.63	0.06	0.93	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	SYPL2	0.07	0.04	blup	45	0.03	4.9e-04	5.4	-6.6	5.5e-11	0.56	0.08	0.90	TRUE