Hub : Genes

PSMA5

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Cells Transformed fibroblasts 0.1220 0.0520 0.0032 0.019 NA 0.009 NA 0.013 0.014 NA 0.0680 NA 0.034
2 YFS Blood 0.0244 0.0098 0.0036 0.000 0.007 0.005 0.01 0.001 0.450 0.0017 0.0091 0.00024 0.110

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.4 0.6 1.1 -0.2 1.0
Bipolar Disorder or Schizophrenia 0.1 0.2 0.4 0.0 -0.7
Depressed Affect (Nagel 2018) 0.2 0.5 0.6 -0.8 0.6
Depression (Nagel 2018) 0.0 0.1 0.1 -0.2 0.3
Intelligence (Savage-Jansen 2018) 1.3 4.1 7.0 -2.6 1.1
Neuroticism (Nagel 2018) 0.4 0.9 1.8 -1.4 0.2
Schizophrenia (2018) 1.1 2.4 2.6 -1.5 -1.6
Schizophrenia vs Biploar Disorder 0.3 0.4 0.7 0.4 -0.8
Worry (Nagel 2018) 0.5 1.0 2.1 -1.4 -0.1
Alzheimer’s Disease (in mother) 1.3 1.5 2.8 -1.7 0.4
Alzheimer’s Disease (in father) 1.7 1.8 2.4 1.6 1.1
Alzheimer’s Disease (including proxy) 0.8 1.2 1.9 -0.7 1.4
Crohns Disease (2017) 0.1 0.3 0.3 -0.6 0.4
Irritable Bowel Disease (IBD) 0.1 0.1 0.3 0.1 0.5
Ulcerative Colitis (UC) 0.2 0.3 0.4 0.5 0.7
Major Depression (MDD) 2.8 3.4 4.0 -2.0 -1.7
Reaction Time 0.1 0.1 0.2 0.1 0.5
Verbal and Numeric Reasoning (VNR) 1.0 2.4 2.6 -1.5 1.6
Breast Cancer 2.9 6.9 13.5 -0.5 -3.7
Ovarian Cancer 0.2 0.2 0.3 0.4 -0.5
Prostate Cancer 0.6 0.8 1.5 0.4 -1.2
Age at First Birth 0.3 0.4 0.5 0.7 0.5
Bipolar Disorder (2011) 0.7 0.7 1.4 0.0 1.2
Body Mass Index (BMI) (2010) 0.9 1.2 2.3 -1.5 0.5
Coronary Artery Disease (CAD) 0.5 0.6 1.0 0.5 1.0
Crohns Disease (2012) 0.4 0.7 0.8 -0.8 0.9
Mean Putamen Volume 1.3 1.5 1.5 1.2 1.2
Fasting Glucose 0.2 0.3 0.5 -0.7 0.3
HbA1C 1.0 1.1 1.7 -1.3 -0.7
HDL Cholesterol 0.1 0.2 0.3 -0.1 0.5
LDL Cholesterol 9.2 14.5 20.3 4.5 3.0
Lupus 0.5 0.8 1.5 -1.2 -0.1
Neuroticism (2016) 1.0 1.4 2.5 -0.6 1.6
Primary Biliary Cirrhosis 0.0 0.1 0.1 -0.3 0.1
Rheumatoid Arthritis 0.3 0.4 0.9 0.1 -0.9
Schizophrenia (2014) 1.3 3.0 4.8 -2.2 -1.0
Triglycerides 0.2 0.4 0.5 -0.6 -0.7
Type 2 Diabetes (T2D) (2012) 0.4 0.5 0.9 -0.0 1.0
Ulcerative Colitis 1.1 1.6 3.1 1.8 -0.2
Blood Eosinophil Count 0.1 0.5 0.8 -0.5 0.9
Blood Platelet Count 0.3 3.2 3.4 1.9 -1.7
Blood Red Count 0.3 3.0 4.2 -2.0 1.4
Blood White Count 0.1 0.5 0.8 -0.9 -0.6
Heel T-Score 0.7 5.4 6.7 -2.6 2.0
BMI 3.1 17.8 29.1 -5.4 2.6
Height 0.1 1.7 2.5 1.0 -1.6
Waist Hip Ratio (WHR) 0.3 1.2 2.4 -1.6 0.1
Systolic Blood Pressure 0.1 0.6 0.9 -0.6 1.0
Smoking Status 0.1 0.2 0.4 -0.1 0.6
Allergy or Eczema 1.2 3.1 5.1 -1.0 2.3
Cardiovascular Disease 0.0 0.1 0.2 0.2 0.4
Hypothyroidism (self reported) 2.5 5.8 10.7 -3.3 0.9
Respiratory disease 2.3 5.1 8.3 -2.9 -1.4
Type 2 Diabetes (T2D) (2018) 1.6 3.0 6.0 0.3 2.5
Lung FEV1/FVC ratio 0.6 3.0 5.7 -0.6 2.4
Lung FVC 0.5 2.4 2.5 1.6 -1.5
Neuroticism 1.3 3.2 5.5 -2.4 0.9
Chronotype (morning person) 4.0 9.2 17.6 -0.8 -4.2
Hair Pigment 0.0 0.5 0.9 0.3 0.9
Tanning 0.1 1.1 1.2 1.1 1.0
Hand grip strength (left) 0.4 1.0 1.6 1.2 -0.6
Number of treatments/medications taken 0.8 1.4 1.5 -1.2 1.1
Average weekly spirits intake 0.3 0.4 0.6 -0.5 -0.8
Sensitivity / hurt feelings 2.2 3.8 6.8 -2.6 -0.9
Frequency of depressed mood in last 2 weeks 1.3 1.8 3.6 -0.1 1.9
Hearing difficulty/problems: Yes 0.3 0.5 0.9 1.0 -0.0
Relative age of first facial hair 0.4 0.9 1.7 1.3 0.1
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 0.5 -0.2 0.7
Ever used hormone-replacement therapy (HRT) 0.1 0.1 0.2 0.5 0.2
Ever had hysterectomy (womb removed) 0.5 0.6 1.2 0.0 -1.1
Systolic blood pressure, automated reading 0.1 0.4 0.6 -0.4 0.8
Eye problems/disorders: Diabetes related eye disease 0.0 0.0 0.0 0.1 0.0
Angina 0.1 0.1 0.2 0.4 0.3
Medication for hormone replacement therapy 1.6 1.8 3.6 0.3 -1.9
Vitamin and mineral supplements 0.5 0.7 1.3 1.1 0.4
Supplements: Zinc 0.7 0.8 1.4 -1.2 -0.3
Medication: Co-codamol 0.8 1.0 1.2 1.1 0.9
Medication: Metformin 1.3 1.9 3.4 -0.6 1.8
Diabetes (father) 0.1 0.1 0.1 -0.4 -0.4
Diabetes (mother) 0.3 0.4 0.7 0.8 -0.2
Severe depression (siblings) 1.1 1.2 2.5 1.6 0.1
Pack years adult smoking proportion 1.0 1.6 1.9 1.4 -1.1
Impedance of leg (right) 4.0 19.6 35.5 6.0 -1.9
Leg fat-free mass (left) 1.3 6.7 12.3 -3.5 1.0
Trunk fat percentage 0.7 2.7 4.9 -0.7 2.2
Hand grip strength (right) 0.3 0.9 1.1 1.0 -0.8
Townsend deprivation index at recruitment 1.0 1.3 2.3 -1.5 -0.6
Current tobacco smoking 0.2 0.4 0.6 0.3 0.8
Average weekly fortified wine intake 0.1 0.1 0.2 -0.4 -0.0
Maternal smoking around birth 0.6 0.8 1.2 -1.1 0.6
Fed-up feelings 1.8 3.3 6.5 -2.5 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 1.9 -0.4 1.4
Relative age voice broke 0.4 0.7 1.2 0.4 1.1
Taking other prescription medications 1.4 2.2 3.2 -1.8 1.1
Age when periods started (menarche) 0.1 0.3 0.5 0.3 -0.7
Bilateral oophorectomy (both ovaries removed) 2.9 3.3 5.2 1.2 -2.3
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.9 2.4 -1.5 1.2
Tinnitus: Yes, but not now, but have in the past 0.5 0.6 1.0 -1.0 0.4
Qualifications: CSEs or equivalent 1.2 1.6 2.5 -0.8 -1.6
Serious illness, injury or assault to yourself 0.6 0.8 1.5 -1.2 0.2
High blood pressure 0.3 0.9 1.0 -0.9 1.0
Hayfever, allergic rhinitis or eczema 0.6 1.4 2.4 -0.6 1.5
Multivitamins +/- minerals 0.4 0.5 0.9 -0.2 -0.9
Stomach or abdominal pain in last month 1.5 1.8 3.4 1.9 -0.5
Supplements: Glucosamine 1.2 1.5 3.0 -1.7 -0.0
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 1.4 -1.2 -0.5
Medication: Atenolol 0.2 0.2 0.5 -0.2 0.7
Medication: Levothyroxine sodium 2.2 3.7 7.4 -2.7 -0.3
Sitting height 0.0 0.0 0.1 0.0 0.3
Chronic bronchitis/emphysema (father) 1.9 2.3 3.6 -1.9 1.0
High blood pressure (mother) 0.2 0.2 0.4 0.2 0.7
Body mass index (BMI) 2.1 8.8 11.3 -3.4 2.5
Impedance of leg (left) 3.6 17.6 33.8 5.8 -1.2
Leg predicted mass (left) 1.3 6.8 12.7 -3.6 1.0
Trunk fat mass 0.7 3.1 4.6 -1.3 2.1
Waist circumference 2.0 7.2 9.6 -3.1 2.2
Number of incorrect matches in round 1.0 1.6 2.8 0.7 -1.7
Past tobacco smoking 1.1 2.1 2.8 -1.7 1.2
Alcohol usually taken with meals 1.0 1.6 2.6 -0.8 -1.6
Nervous feelings 0.2 0.4 0.5 -0.7 0.6
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 1.6 -0.4 1.3
Hearing difficulty/problems with background noise 0.1 0.2 0.2 -0.5 -0.3
Hair/balding pattern: Pattern 2 2.0 2.5 5.0 0.1 -2.2
Had menopause 1.0 1.2 1.8 0.8 -1.4
Had other major operations 0.2 0.3 0.6 -0.8 0.1
Forced vital capacity (FVC) 0.8 3.2 5.4 2.3 -1.0
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.4 3.6 -1.9 1.0
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 0.3 0.6 -0.3
Qualifications: None of the above 0.1 0.2 0.3 0.6 0.2
Financial difficulties in last 2 years 1.2 1.5 2.0 -1.0 -1.4
Mouth/teeth dental problems 0.4 0.7 1.3 -1.1 -0.1
Heart attack 0.5 0.7 1.4 0.2 1.2
Allergy 0.8 1.9 2.2 1.5 -1.3
Pain all over the body in last month 0.1 0.1 0.3 -0.0 0.5
Diabetes (self-reported) 0.9 1.3 2.6 -0.1 1.6
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 1.6 1.3 0.1
Medication: Ramipril 0.4 0.5 1.0 0.2 1.0
Medication: Simvastatin 1.3 1.9 3.5 0.6 1.9
Fluid intelligence score 0.5 1.0 1.1 -1.0 0.9
Illnesses of siblings 0.8 1.2 1.9 0.7 -1.4
Neuroticism score 1.4 2.9 5.2 -2.3 0.8
Weight 1.0 5.2 7.0 -2.6 1.8
Impedance of arm (right) 1.6 7.6 13.9 3.7 -1.1
Arm fat percentage (right) 1.1 4.3 5.7 -1.7 2.4
Trunk fat-free mass 0.6 3.3 6.5 -2.5 0.4
Hip circumference 1.0 4.4 4.6 -2.1 2.1
Time employed in main current job 0.0 0.0 0.0 0.1 -0.1
Alcohol intake versus 10 years previously 0.1 0.1 0.1 -0.2 0.4
Father’s age at death 0.3 0.4 0.6 -0.8 0.4
Worrier / anxious feelings 0.1 0.2 0.4 -0.6 -0.1
Frequency of tiredness / lethargy in last 2 weeks 2.2 3.7 4.6 -1.6 2.1
Falls in the last year 0.1 0.2 0.3 0.6 -0.2
Hair/balding pattern: Pattern 3 1.1 1.6 2.2 1.0 -1.5
Number of live births 0.3 0.5 0.9 -0.3 1.0
Forced expiratory volume in 1-second (FEV1) 0.8 2.7 4.3 2.1 -1.0
Pulse rate 0.9 1.6 1.8 -1.3 -1.2
Happiness 0.7 0.9 1.7 0.0 1.3
Noisy workplace 2.6 3.2 5.2 2.3 1.1
Qualifications: A levels/AS levels or equivalent 0.0 0.0 0.0 0.1 -0.2
Serious illness, injury or assault of a close relative in last 2 years 0.8 1.0 1.6 -1.3 0.6
Mouth/teeth dental problems: Dentures 0.1 0.1 0.3 0.5 0.1
Asthma 1.8 3.5 3.6 -1.9 -1.9
Medication: Ibuprofen (e.g. Nurofen) 0.0 0.0 0.0 0.2 -0.1
Medication: Cholesterol lowering 2.8 4.4 5.5 1.8 2.3
Depression (self-reported) 1.1 1.3 1.6 -1.3 0.9
Medication: Lansoprazole 0.2 0.2 0.4 -0.6 0.2
Prospective memory result 0.9 1.1 2.0 -1.4 -0.5
Lung cancer (father) 3.5 4.0 5.7 2.4 -1.6
Illnesses of mother 0.8 1.0 1.9 -0.4 -1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 0.3 0.5 -0.4
Pulse wave Arterial Stiffness index 1.0 1.2 2.0 0.5 1.4
Impedance of arm (left) 1.1 5.3 9.2 3.0 -1.2
Arm fat mass (right) 1.3 5.2 5.3 -2.3 2.3
Trunk predicted mass 0.6 3.5 6.8 -2.6 0.4
Standing height 0.1 1.4 1.7 1.3 -1.1
Length of working week for main job 0.4 0.5 0.7 0.5 -0.8
Exposure to tobacco smoke at home 2.2 2.5 4.8 0.5 2.2
Breastfed as a baby 0.1 0.1 0.1 0.1 0.4
Tense / ‘highly strung’ 0.7 1.2 1.8 -1.4 0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 1.4 -1.2 -0.5
Hair/balding pattern: Pattern 4 0.5 1.3 2.0 -0.8 1.4
Birth weight of first child 0.4 0.7 0.9 -0.9 0.8
Peak expiratory flow (PEF) 2.3 5.4 6.4 2.1 -2.5
Pulse wave reflection index 1.0 1.3 1.8 1.3 0.9
Ever highly irritable/argumentative for 2 days 0.0 0.0 0.0 0.1 -0.1
Loud music exposure frequency 1.5 1.6 2.3 -1.0 -1.5
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.2 -0.1 -0.5
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.2 0.1 -0.4
Blood clot in the leg (DVT) 0.3 0.4 0.6 -0.8 -0.5
Medication: Paracetamol 1.3 2.2 4.2 -0.3 -2.1
Headache pain in last month 0.2 0.3 0.3 0.5 0.6
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 3.1 -0.5 -1.8
Glaucoma (self-reported) 0.4 0.5 1.0 0.2 1.0
Gout (self-reported) 0.0 0.1 0.1 -0.1 -0.3
Hypothyroidism/myxoedema (self-reported) 1.7 3.4 6.6 -2.6 -0.5
Medication: Amlodipine 0.0 0.0 0.0 0.2 0.1
Medication: Ventolin 100micrograms inhaler 2.0 2.6 2.6 -1.6 -1.6
Birth weight 0.9 1.9 3.2 -1.8 0.8
Chronic bronchitis/emphysema (mother) 1.3 1.5 2.4 -0.8 1.6
High blood pressure (siblings) 2.1 3.0 5.1 -1.0 2.3
Forced vital capacity (FVC), Best measure 0.3 1.1 1.8 1.4 -0.6
Body fat percentage 0.8 3.2 5.9 -0.8 2.4
Leg fat percentage (right) 0.6 2.1 4.1 -0.3 2.0
Arm fat-free mass (right) 0.8 4.1 7.9 -2.8 0.5
Exposure to tobacco smoke outside home 5.8 7.7 8.7 2.9 2.6
Comparative body size at age 10 1.7 4.8 5.2 -2.3 2.1
Number of full brothers 0.8 1.0 1.8 1.4 0.5
Worry too long after embarrassment 0.7 1.1 1.3 -0.9 1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 0.5 -0.2 -0.7
Wheeze or whistling in the chest in last year 0.2 0.4 0.7 0.1 -0.8
Number of children fathered 0.4 0.4 0.7 0.8 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 0.7 0.7 -0.8
Age at first live birth 0.2 0.3 0.4 -0.4 0.7
Pulse wave peak to peak time 0.8 1.0 1.6 -0.6 -1.3
Health satisfaction 0.3 0.3 0.4 -0.6 0.6
Shortness of breath walking on level ground 0.0 0.0 0.1 -0.0 -0.3
Qualifications: College or University degree 2.3 7.3 14.6 -3.8 0.3
Eye problems/disorders: None of the above 1.6 1.8 2.0 -1.3 1.4
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.1 0.3 0.3
Emphysema/chronic bronchitis 0.1 0.1 0.2 -0.5 -0.1
Medication for pain relief, constipation, heartburn 0.4 0.7 1.3 0.3 1.1
Neck or shoulder pain in last month 0.9 1.3 2.5 1.6 0.1
Medication: Blood pressure 0.5 0.9 1.2 -0.8 1.1
Angina (self-reported) 0.2 0.2 0.2 0.5 0.4
Migraine (self-reported) 0.2 0.3 0.3 0.5 -0.5
Medication: Ibuprofen 0.3 0.3 0.4 -0.6 -0.5
Medication: Allopurinol 0.3 0.4 0.5 -0.6 0.7
Medication: Omeprazole 0.0 0.1 0.1 -0.3 -0.1
Medication: Seretide 50 evohaler 1.4 1.6 2.5 -1.6 -0.8
Mean time to correctly identify matches 0.2 0.5 0.9 0.1 1.0
Heart disease (mother) 0.4 0.5 1.0 1.0 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 1.7 1.3 -0.7
Whole body fat mass 0.8 3.3 4.5 -1.4 2.1
Leg fat mass (right) 0.9 3.4 4.5 -1.5 2.1
Arm predicted mass (right) 0.7 3.5 6.9 -2.6 0.4
Pulse rate, automated reading 0.1 0.4 0.8 0.2 -0.9
Alcohol intake frequency. 0.5 1.1 1.7 -1.3 -0.6
Comparative height size at age 10 0.2 0.9 1.3 1.2 0.6
Number of full sisters 0.1 0.1 0.2 0.2 -0.5
Suffer from ‘nerves’ 0.2 0.3 0.6 -0.8 -0.1
Overall health rating 1.9 4.0 6.1 -2.5 1.4
Chest pain or discomfort 0.4 0.6 1.2 -0.2 1.1
Had major operations 2.7 3.1 6.2 -0.2 2.5
Age at last live birth 1.5 2.1 3.2 -1.8 1.1
Family relationship satisfaction 1.1 1.3 2.3 1.5 0.6
Leg pain on walking 0.1 0.1 0.1 0.2 -0.3
Qualifications: NVQ or HND or HNC or equivalent 1.6 1.9 2.8 1.7 -1.0
Commuting to job workplace: Car/motor vehicle 0.7 0.8 0.9 1.0 0.8
Illness, injury, bereavement, stress in last 2 years 1.1 1.3 2.5 1.6 0.3
Medication: Aspirin 0.0 0.0 0.0 -0.2 -0.2
Supplements: Vitamin C 1.7 2.0 2.9 -1.7 -1.1
Knee pain experienced in last month 1.1 1.7 2.1 -1.4 -1.1
Hypertension (Self-reported) 0.3 0.9 0.9 -1.0 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 0.9 -0.9 1.0
Illnesses of father: Heart disease 4.4 6.0 10.7 -1.2 3.3
Illnesses of siblings: Diabetes 1.0 1.2 2.0 1.4 -0.6
Smoking status: Previous 1.1 1.6 2.2 1.0 -1.5
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 0.4 -0.6 -0.6
Whole body fat-free mass 0.9 5.4 10.1 -3.2 0.8
Leg fat-free mass (right) 1.4 7.7 13.8 -3.7 1.2
Arm fat percentage (left) 1.1 4.3 5.1 -1.9 2.2
Average weekly red wine intake 0.1 0.1 0.1 -0.2 -0.3
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.0 -0.5 1.0
Mood swings 1.5 2.7 4.2 -1.1 2.1
Loneliness, isolation 1.2 1.6 2.0 -1.1 1.4
Long-standing illness, disability or infirmity 0.9 1.4 2.2 -0.7 1.5
Ever had bowel cancer screening 0.2 0.2 0.4 -0.3 0.6
Diabetes diagnosed by doctor 0.9 1.4 2.8 0.1 1.7
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.2 0.5 -0.2
Friendships satisfaction 0.3 0.3 0.6 0.2 0.8
Qualifications: nursing, teaching 0.2 0.3 0.4 -0.4 0.6
Commuting to job workplace: Walk 0.7 0.8 1.2 0.6 -1.1
Eye problems/disorders: Cataract 2.8 3.2 5.2 1.1 -2.3
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 0.7 0.9 0.3
Medication for cholesterol 0.7 1.1 1.6 1.3 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.0 -1.0 0.1
Back pain experienced in last month 0.7 1.1 1.2 1.1 1.0
Mineral and other dietary supplements 0.3 0.5 0.7 0.4 0.9
Breast cancer (self-reported) 0.1 0.1 0.2 0.5 -0.2
Asthma (self-reported) 2.0 3.9 4.2 -1.9 -2.0
Osteoporosis (self-reported) 0.1 0.1 0.1 0.4 0.4
Osteoarthritis (self-reported) 1.0 1.3 2.0 -1.4 0.8
Medication: Aspirin 0.0 0.0 0.0 0.2 -0.1
Medication: Gliclazide 1.8 2.1 2.6 -1.3 1.6
Illnesses of father: None of the above (group 1) 7.4 9.1 14.3 2.0 -3.8
Smoking status: Current 0.2 0.3 0.4 0.5 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.5 -0.1 0.7
Whole body water mass 0.9 5.3 10.1 -3.2 0.7
Leg predicted mass (right) 1.4 7.3 13.2 -3.6 1.2
Arm fat mass (left) 1.4 5.7 6.0 -2.5 2.3
Number of self-reported non-cancer illnesses 0.9 1.5 2.1 -1.0 1.5
Average weekly champagne plus white wine intake 0.2 0.3 0.5 -0.3 0.7
Miserableness 0.5 0.8 1.7 -0.1 1.3
Guilty feelings 0.4 0.6 1.0 -1.0 0.4
Wears glasses or contact lenses 0.4 0.5 0.8 -0.4 0.9
Ever taken oral contraceptive pill 0.2 0.2 0.3 0.5 0.4
Hearing aid user 0.9 1.0 2.1 0.1 1.4
Mother’s age at death 0.1 0.2 0.3 -0.2 -0.5
Financial situation satisfaction 0.1 0.2 0.3 0.5 0.3
Tinnitus: Yes, now most or all of the time 1.0 1.2 2.2 -0.4 1.5
Commuting to job workplace: Public transport 0.1 0.2 0.2 -0.3 0.5
Eye problems/disorders: Glaucoma 0.0 0.0 0.0 0.2 -0.2
Medication: Blood pressure 0.2 0.5 0.9 -0.9 0.3
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.3 0.5 -0.2
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.2 -0.1 -0.5
High cholesterol (Self-reported) 1.9 3.3 3.3 1.8 1.8
Medication: Bendroflumethiazide 0.6 0.9 1.8 -1.3 -0.1
Medication: Paracetamol 1.5 2.3 3.8 -0.9 -1.9
Medication: Lisinopril 0.9 1.2 1.5 -0.9 1.2
Medication: Atorvastatin 0.6 0.8 1.4 1.2 0.4
Illnesses of father: High blood pressure 0.6 0.8 1.4 -0.5 1.2
Alcohol drinker status: Never 1.3 1.6 2.8 -1.7 -0.5
Ever smoked 0.3 0.6 0.9 0.9 -0.5
Basal metabolic rate 1.0 5.3 9.5 -3.1 1.1
Leg fat percentage (left) 0.9 3.2 6.2 -0.5 2.5
Arm fat-free mass (left) 0.6 3.2 5.9 -2.4 0.7
Number of operations (self-reported) 0.0 0.0 0.0 0.1 -0.1
Average weekly beer plus cider intake 1.1 1.5 2.9 1.7 0.4
Irritability 0.1 0.2 0.4 -0.6 0.0
Risk taking 0.7 1.0 1.1 0.9 -1.0
Ever had prostate specific antigen (PSA) test 0.3 0.3 0.5 0.7 -0.4
Fractured/broken bones in last 5 years 0.6 0.7 1.4 0.2 -1.2
Age started oral contraceptive pill 1.4 1.8 2.0 -1.4 1.2
Diastolic blood pressure, automated reading 0.2 0.6 0.6 -0.8 0.7
Ever depressed for a whole week 0.1 0.1 0.1 0.3 -0.2
Unable to work because of sickness or disability 0.1 0.1 0.1 -0.4 -0.1
Commuting to job workplace: Cycle 0.9 1.1 1.4 -1.2 -1.0
Myopia 1.0 1.4 1.8 -1.4 1.0
Vascular/heart problems diagnosed by doctor 0.5 1.3 1.7 1.0 -1.3
Cholesterol lowering medication 0.5 0.7 1.3 0.3 1.2
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.0 -1.0 -0.5
Pain experienced in last month 0.1 0.2 0.3 -0.5 -0.3
Supplements: Calcium 0.0 0.0 0.1 -0.3 -0.1
Basal cell carcinoma (self-reported) 0.5 0.6 1.0 -1.0 0.5
Heart attack/myocardial infarction (self-reported) 0.5 0.6 1.3 0.1 1.1
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 0.5 -0.7 -0.5
Heart disease (siblings) 0.5 0.6 1.2 -0.2 1.1
Alcohol drinker status: Previous 3.1 3.5 3.6 -1.9 -1.9
Pack years of smoking 0.9 1.4 2.0 1.4 -0.9
Impedance of whole body 2.6 13.0 23.7 4.9 -1.5
Leg fat mass (left) 1.0 3.7 5.1 -1.5 2.3
Arm predicted mass (left) 0.6 3.2 5.9 -2.4 0.8