[Hub]/) : Traits : BMI : ← →

chr2:24,021,231-26,088,769

Best TWAS P=3.09e-77 · Best GWAS P=1.07e-71 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	17.61	-18.4	5.3e-76	-0.89	0.00	1.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	8.69	-13.4	5.3e-41	-0.49	0.50	0.21	TRUE
3	CommonMind	Brain Pre-frontal Cortex	DNAJC27	0.14	0.14	lasso	5	0.14	2.0e-16	5.14	-5.1	2.8e-07	-0.29	1.00	0.00	FALSE
4	CommonMind	Brain Pre-frontal Cortex	POMC	0.38	0.22	lasso	11	0.26	6.9e-32	-3.33	-5.3	9.2e-08	-0.03	1.00	0.00	FALSE
5	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	16.70	16.2	9.9e-59	0.87	0.07	0.92	FALSE
6	GTEx	Adipose Subcutaneous	RP11-443B20.1	0.04	0.00	enet	10	0.00	1.2e-01	10.23	13.7	6.8e-43	0.82	0.04	0.90	FALSE
7	GTEx	Adrenal Gland	PTRHD1	0.32	0.28	lasso	3	0.26	8.3e-10	-9.88	10.4	2.2e-25	0.41	0.98	0.00	FALSE
8	GTEx	Artery Coronary	DNAJC27	0.12	0.03	lasso	7	0.00	2.4e-01	5.29	8.2	2.9e-16	0.46	0.14	0.21	FALSE
9	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	15.47	16.7	7.4e-63	0.70	0.99	0.00	TRUE
10	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	15.47	14.9	2.5e-50	0.59	0.64	0.31	TRUE
11	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	16.70	-15.2	1.7e-52	-0.84	0.02	0.97	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	16.70	-17.5	2.7e-68	-0.93	0.01	0.96	FALSE
13	GTEx	Esophagus Mucosa	ADCY3	0.06	0.05	lasso	3	0.03	6.8e-03	5.29	5.2	1.6e-07	0.30	0.58	0.05	FALSE
14	GTEx	Esophagus Muscularis	NCOA1	0.11	0.01	enet	9	0.01	5.8e-02	4.38	6.7	1.9e-11	0.45	0.08	0.11	FALSE
15	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	15.47	-18.6	3.1e-77	-0.92	0.01	0.99	TRUE
16	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	15.47	-17.6	1.3e-69	-0.82	0.02	0.98	FALSE
17	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	16.43	16.4	1.2e-60	0.80	0.85	0.15	FALSE
18	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	16.81	18.0	1.8e-72	0.87	1.00	0.00	FALSE
19	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	16.43	18.2	4.4e-74	0.87	0.74	0.26	FALSE
20	METSIM	Adipose	EFR3B	0.04	0.00	bslmm	357	0.00	9.7e-02	-4.17	-11.4	2.7e-30	-0.37	0.06	0.08	FALSE
21	METSIM	Adipose	POMC	0.18	0.06	lasso	9	0.09	5.5e-13	-3.56	-7.1	1.6e-12	-0.16	1.00	0.00	TRUE
22	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	16.81	-18.0	3.3e-72	-0.90	0.93	0.07	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	CENPO	0.08	0.04	enet	5	0.05	2.6e-07	-7.12	-8.7	2.5e-18	-0.36	1.00	0.00	FALSE
24	YFS	Blood	ADCY3	0.07	0.02	bslmm	343	0.04	7.3e-14	17.91	-10.5	1.4e-25	-0.63	0.00	1.00	FALSE
25	YFS	Blood	DNAJC27	0.07	0.04	blup	333	0.05	3.1e-17	5.27	-5.5	4.0e-08	-0.21	1.00	0.00	FALSE
26	YFS	Blood	POMC	0.35	0.05	enet	71	0.19	5.7e-59	-12.61	-11.1	2.2e-28	-0.30	1.00	0.00	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADCY3	0.05	0.03	blup	81	0.03	5.0e-07	3.62	-9.4	7.5e-21	-0.51	0.49	0.47	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	DNAJC27	0.04	0.01	enet	8	0.02	6.8e-05	-0.93	-5.6	2.2e-08	-0.17	0.19	0.06	FALSE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	POMC	0.08	0.05	lasso	3	0.06	2.6e-12	-3.33	-9.1	7.5e-20	-0.20	0.63	0.37	FALSE
30	The Cancer Genome Atlas	Glioblastoma Multiforme	ADCY3	0.36	0.14	enet	7	0.13	8.9e-05	4.79	-5.3	1.0e-07	-0.37	0.04	0.15	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	POMC	0.06	0.00	enet	12	0.03	9.3e-05	-3.33	-9.2	2.7e-20	-0.26	0.01	0.62	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFR3B	0.03	0.05	lasso	1	0.04	1.9e-05	-13.70	-13.7	1.0e-42	-0.65	0.56	0.06	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	POMC	0.16	0.05	blup	39	0.11	2.4e-12	-12.61	-7.9	2.3e-15	-0.21	0.00	1.00	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	11.76	-16.3	1.1e-59	-0.88	0.03	0.95	FALSE
35	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC27	0.05	0.01	blup	46	0.04	3.2e-05	5.27	-10.4	3.1e-25	-0.56	0.37	0.57	TRUE
36	The Cancer Genome Atlas	Lung Adenocarcinoma	NCOA1	0.02	0.01	blup	77	0.01	1.2e-02	-5.26	-7.3	3.6e-13	-0.23	0.03	0.73	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	POMC	0.14	0.04	enet	7	0.08	5.3e-10	-3.33	-10.1	6.8e-24	-0.21	0.10	0.89	FALSE
38	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DNAJC27	0.04	0.04	lasso	1	0.02	1.2e-02	5.16	-5.2	2.4e-07	-0.30	0.09	0.07	FALSE
39	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	POMC	0.19	0.01	blup	38	0.05	1.5e-04	-12.61	-10.2	1.3e-24	-0.32	0.00	0.85	TRUE
40	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DNAJC27	0.12	0.12	lasso	2	0.09	1.7e-04	5.17	-5.2	2.4e-07	-0.30	0.58	0.12	FALSE
41	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	POMC	0.22	0.05	blup	37	0.03	2.1e-02	-4.13	-8.3	9.8e-17	-0.11	0.01	0.10	TRUE
42	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DNAJC27	0.07	0.09	lasso	2	0.10	8.2e-05	5.17	-5.2	2.4e-07	-0.30	0.22	0.10	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	DNAJC27	0.07	0.03	enet	13	0.06	1.3e-06	5.17	-5.5	4.1e-08	-0.21	0.74	0.02	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	POMC	0.11	0.08	enet	7	0.09	1.6e-09	-3.33	-10.2	1.5e-24	-0.23	0.13	0.87	FALSE
45	The Cancer Genome Atlas	Stomach Adenocarcinoma	POMC	0.14	0.00	blup	40	0.02	2.2e-02	-4.13	-8.1	6.0e-16	-0.14	0.00	0.62	FALSE