[Hub]/) : Traits : BMI : ← →

chr22:37,337,772-39,306,784

Best TWAS P=2.1e-10 · Best GWAS P=8.08e-08 conditioned to 0.968

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TRIOBP 0.13 0.14 lasso 7 0.14 3.9e-11 5.1 -5.2 2.4e-07 -0.86 0.05 0.95 FALSE
2 GTEx Adipose Subcutaneous ANKRD54 0.14 0.02 enet 18 0.06 5.9e-06 -4.9 -5.6 1.8e-08 -0.27 0.04 0.74 FALSE
3 GTEx Artery Aorta C22orf23 0.10 0.01 enet 24 0.02 1.6e-02 4.0 6.4 2.1e-10 0.70 0.06 0.76 TRUE
4 GTEx Artery Aorta PLA2G6 0.10 0.02 enet 9 0.02 4.5e-02 3.7 5.8 6.7e-09 0.28 0.12 0.30 FALSE
5 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 3.4 -5.3 9.2e-08 -0.30 0.10 0.10 FALSE
6 GTEx Artery Tibial MICALL1 0.11 0.04 lasso 4 0.05 8.4e-05 4.3 5.2 2.2e-07 0.66 0.28 0.54 FALSE
7 GTEx Cells Transformed fibroblasts ANKRD54 0.11 0.09 lasso 4 0.09 5.3e-07 -4.9 -5.6 1.9e-08 -0.44 0.03 0.96 FALSE
8 GTEx Muscle Skeletal GCAT 0.13 0.10 enet 17 0.10 3.9e-10 5.1 5.5 3.0e-08 0.88 0.03 0.96 FALSE
9 GTEx Muscle Skeletal ANKRD54 0.15 0.02 enet 21 0.04 1.1e-04 -4.9 -5.5 2.9e-08 -0.38 0.08 0.90 FALSE
10 GTEx Skin Sun Exposed Lower leg ANKRD54 0.07 0.04 enet 17 0.04 1.6e-04 -4.9 -5.5 4.3e-08 -0.47 0.04 0.92 FALSE
11 NTR Blood SH3BP1 0.02 0.00 blup 497 0.01 5.0e-03 4.1 5.3 1.4e-07 0.65 0.04 0.58 FALSE
12 ROSMAP Brain Pre-frontal Cortex ANKRD54 0.03 0.00 blup 397 0.01 2.2e-02 3.5 -5.5 4.2e-08 -0.73 0.10 0.44 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma TRIOBP 0.07 0.04 blup 67 0.03 2.1e-04 4.9 -5.2 1.8e-07 -0.87 0.03 0.96 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma GCAT 0.02 0.03 blup 29 0.03 1.4e-03 5.1 5.3 1.3e-07 0.86 0.01 0.80 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma GGA1 0.04 0.01 blup 55 0.02 1.7e-03 4.7 5.9 4.6e-09 0.46 0.00 0.86 TRUE