[Hub]/) : Traits : BMI :

chr22:39,745,241-43,232,818

Best TWAS P=1.3e-17 · Best GWAS P=4.68e-16 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC134 0.06 0.07 enet 5 0.06 1.2e-07 -4.1 -5.1 3.1e-07 -0.03 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex EP300 0.05 0.00 bslmm 289 0.02 3.2e-03 4.1 -5.8 8.6e-09 0.16 0.44 0.07 FALSE
3 GTEx Adipose Visceral Omentum TNRC6B 0.11 0.00 lasso 4 0.01 1.5e-01 -2.3 -6.7 1.5e-11 0.26 0.04 0.38 TRUE
4 GTEx Brain Cerebellar Hemisphere CYP2D7P1 0.39 0.09 enet 12 0.20 7.2e-06 -3.1 -5.1 2.7e-07 0.04 0.18 0.44 FALSE
5 GTEx Brain Frontal Cortex BA9 SLC25A17 0.11 -0.01 lasso 5 0.00 3.5e-01 -4.5 -5.2 1.7e-07 0.35 0.08 0.15 FALSE
6 GTEx Breast Mammary Tissue (Male) CYP2D7P1 0.32 0.00 lasso 8 0.02 9.7e-02 4.1 -5.9 4.9e-09 0.02 0.03 0.06 TRUE
7 GTEx Liver L3MBTL2 0.13 0.08 lasso 7 0.09 1.3e-03 -4.8 5.2 2.1e-07 0.00 0.07 0.54 FALSE
8 GTEx Skin Sun Exposed Lower leg CENPM 0.05 0.00 enet 8 0.02 1.5e-02 -3.8 5.6 2.1e-08 0.00 0.09 0.23 FALSE
9 GTEx Thyroid ZC3H7B 0.11 0.07 enet 7 0.07 3.9e-06 4.1 5.3 1.2e-07 -0.14 0.30 0.33 TRUE
10 The Cancer Genome Atlas Breast Invasive Carcinoma ADSL 0.05 0.01 enet 7 0.01 4.2e-04 -2.6 -5.4 6.2e-08 0.46 0.06 0.29 TRUE
11 The Cancer Genome Atlas Breast Invasive Carcinoma TNRC6B 0.02 0.01 blup 92 0.01 2.7e-03 -7.4 -8.3 8.7e-17 0.85 0.02 0.74 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma MKL1 0.05 0.03 blup 105 0.04 3.9e-03 -3.8 -5.4 8.4e-08 0.38 0.04 0.24 TRUE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADSL 0.04 0.03 enet 6 0.03 1.6e-04 -8.1 -7.8 8.8e-15 0.90 0.00 0.94 TRUE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ADSL 0.07 0.02 blup 33 0.05 5.2e-04 -5.3 -7.4 1.2e-13 0.68 0.08 0.48 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SGSM3 0.07 0.02 blup 43 0.03 1.1e-02 -2.4 -5.4 8.1e-08 0.23 0.05 0.04 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma TNRC6B 0.05 0.03 lasso 8 0.04 6.9e-06 -5.8 -7.6 2.3e-14 0.54 0.50 0.42 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma ADSL 0.03 0.00 blup 33 0.01 8.9e-03 -7.9 -8.5 1.3e-17 0.84 0.01 0.60 TRUE
18 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ADSL 0.06 0.02 lasso 2 0.03 6.6e-03 -8.0 -7.7 1.6e-14 0.97 0.00 0.81 FALSE
19 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADSL 0.09 0.03 lasso 3 0.01 7.7e-02 -8.1 -8.0 1.2e-15 0.92 0.00 0.75 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma SGSM3 0.06 0.01 lasso 4 0.01 7.4e-02 7.5 -5.8 6.2e-09 0.30 0.02 0.33 FALSE
21 The Cancer Genome Atlas Soft Tissue Sarcoma ADSL 0.14 0.05 lasso 3 0.06 1.5e-04 -4.8 -6.0 1.6e-09 0.45 0.56 0.05 FALSE
22 The Cancer Genome Atlas Stomach Adenocarcinoma ADSL 0.04 0.00 blup 33 0.03 2.6e-03 -5.4 -8.3 1.0e-16 0.68 0.02 0.74 FALSE
23 The Cancer Genome Atlas Stomach Adenocarcinoma MKL1 0.05 0.01 blup 95 0.02 2.2e-02 6.4 -6.9 5.6e-12 0.47 0.01 0.92 TRUE