[Hub]/) : Traits : Cardiovascular Disease : ← →

chr11:115,953,897-117,800,682

Best TWAS P=1.19e-18 · Best GWAS P=3.16e-18 conditioned to 0.0326

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	CommonMind	Brain Pre-frontal Cortex	ZNF259	0.08	0.03	enet	6	0.03	1.2e-04	7.207	-8.8	1.2e-18	-0.76	0.03	0.97	TRUE
3	GTEx	Cells Transformed fibroblasts	PAFAH1B2	0.11	0.00	lasso	3	0.00	1.3e-01	6.845	-7.1	1.2e-12	-0.42	0.06	0.20	TRUE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZNF259	0.04	0.03	lasso	3	0.02	8.4e-04	7.028	-7.2	4.5e-13	-0.48	0.19	0.08	FALSE
7	GTEx	Testis	TAGLN	0.15	0.05	lasso	5	0.04	8.0e-03	6.077	-6.9	6.2e-12	-0.32	0.36	0.04	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SIDT2	0.07	0.06	lasso	5	0.05	8.8e-07	6.206	-6.7	2.1e-11	-0.29	0.99	0.00	FALSE
8	GTEx	Whole Blood	SIDT2	0.18	0.06	lasso	7	0.04	2.3e-04	6.256	-6.4	1.9e-10	-0.24	0.95	0.00	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	SIDT2	0.11	0.00	blup	46	0.05	8.2e-04	6.256	-6.4	1.9e-10	-0.25	0.01	0.65	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PCSK7	0.04	0.03	lasso	3	0.03	5.6e-04	6.206	6.3	2.5e-10	0.26	0.00	0.99	FALSE
9	METSIM	Adipose	SIDT2	0.09	0.07	lasso	7	0.07	2.3e-10	6.256	-6.3	3.5e-10	-0.30	1.00	0.00	FALSE
4	GTEx	Colon Sigmoid	PCSK7	0.28	0.09	lasso	8	0.15	6.5e-06	6.770	-6.2	4.9e-10	-0.39	0.82	0.02	FALSE
6	GTEx	Pancreas	SIDT2	0.17	0.12	lasso	3	0.08	1.9e-04	6.250	-6.1	1.3e-09	-0.24	0.38	0.05	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	SIDT2	0.08	0.01	blup	46	0.05	2.4e-06	6.068	-6.0	2.2e-09	-0.21	0.02	0.89	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	SIDT2	0.02	0.01	blup	46	0.01	4.6e-02	4.253	-5.9	3.1e-09	-0.26	0.01	0.82	FALSE
11	NTR	Blood	SIDT2	0.12	0.15	lasso	4	0.15	2.3e-46	6.256	-5.8	6.5e-09	-0.22	1.00	0.00	FALSE
10	METSIM	Adipose	TAGLN	0.04	0.04	lasso	4	0.04	2.8e-06	6.256	-5.8	7.3e-09	-0.22	0.97	0.00	FALSE
5	GTEx	Esophagus Muscularis	PCSK7	0.18	0.09	lasso	3	0.10	9.2e-07	6.256	-5.8	8.6e-09	-0.24	0.97	0.00	FALSE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PCSK7	0.04	0.02	blup	51	0.02	4.4e-03	3.678	5.6	1.9e-08	0.25	0.01	0.95	FALSE
12	YFS	Blood	SIDT2	0.40	0.40	enet	46	0.46	1.3e-168	6.250	-5.4	6.0e-08	-0.21	1.00	0.00	FALSE
13	YFS	Blood	TAGLN	0.37	0.47	enet	47	0.54	1.3e-213	3.995	-5.3	1.2e-07	-0.25	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	BUD13	0.08	0.00	blup	76	0.01	9.2e-02	-0.058	-5.2	2.2e-07	-0.22	0.02	0.04	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	SIDT2	0.03	0.03	blup	46	0.03	2.4e-04	6.256	-5.2	2.6e-07	-0.21	0.01	0.97	FALSE