[Hub]/) : Traits : Height :

chr10:63,414,038-66,034,105

Best TWAS P=1.02e-37 · Best GWAS P=3.66e-26 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADO 0.04 0.01 blup 465 0.02 1.8e-03 10.2 7.5 8.0e-14 0.19 0.00 0.96 FALSE
2 CommonMind Brain Pre-frontal Cortex REEP3 0.05 0.05 lasso 3 0.04 5.9e-06 9.0 9.9 3.7e-23 -0.95 0.02 0.98 FALSE
3 GTEx Adipose Subcutaneous REEP3 0.10 0.03 lasso 3 0.03 7.2e-04 -9.8 9.8 1.0e-22 -0.64 0.36 0.37 TRUE
4 GTEx Brain Cortex NRBF2 0.30 0.26 enet 24 0.21 1.4e-06 -9.0 -10.1 5.3e-24 0.95 0.02 0.97 FALSE
5 GTEx Brain Frontal Cortex BA9 NRBF2 0.25 0.17 lasso 6 0.16 6.1e-05 9.0 -9.9 3.9e-23 0.96 0.02 0.97 FALSE
6 GTEx Cells Transformed fibroblasts REEP3 0.18 0.08 enet 9 0.13 1.1e-09 2.1 5.3 1.0e-07 -0.03 0.98 0.00 FALSE
7 GTEx Esophagus Mucosa NRBF2 0.14 0.11 lasso 10 0.11 6.4e-08 8.8 -9.1 6.9e-20 0.89 0.92 0.07 FALSE
8 GTEx Muscle Skeletal ADO 0.15 0.16 lasso 8 0.16 1.1e-15 10.0 10.3 1.2e-24 0.05 0.01 0.99 FALSE
9 GTEx Muscle Skeletal RP11-436D10.3 0.08 0.04 enet 13 0.06 3.2e-06 -7.2 9.4 4.5e-21 0.03 0.01 0.99 TRUE
10 GTEx Nerve Tibial NRBF2 0.08 0.09 enet 11 0.06 5.0e-05 8.8 -7.3 1.9e-13 0.88 0.09 0.90 FALSE
11 GTEx Stomach NRBF2 0.09 0.04 lasso 6 0.03 1.6e-02 -7.2 -9.0 3.0e-19 0.78 0.05 0.60 TRUE
12 GTEx Testis NRBF2 0.14 0.08 lasso 12 0.09 6.7e-05 8.8 -9.6 7.6e-22 0.92 0.14 0.82 FALSE
13 GTEx Testis ADO 0.21 0.23 lasso 7 0.22 6.6e-10 10.0 -10.1 7.3e-24 -0.07 0.01 0.99 FALSE
14 GTEx Thyroid EGR2 0.08 0.01 enet 40 0.02 6.4e-03 4.8 5.2 2.1e-07 -0.01 0.54 0.10 FALSE
15 NTR Blood NRBF2 0.03 0.01 bslmm 386 0.01 3.4e-05 5.1 12.8 1.0e-37 -0.51 0.12 0.45 TRUE
16 ROSMAP Brain Pre-frontal Cortex NRBF2 0.34 0.46 lasso 5 0.46 3.1e-66 9.0 -9.7 3.0e-22 0.94 1.00 0.00 FALSE
17 ROSMAP Brain Pre-frontal Cortex REEP3 0.10 0.11 lasso 8 0.09 7.2e-12 -8.7 9.3 1.0e-20 -0.75 1.00 0.00 FALSE
18 ROSMAP Brain Pre-frontal Cortex ADO 0.06 0.04 lasso 2 0.06 3.1e-08 -7.2 6.2 4.9e-10 0.12 0.96 0.03 FALSE
19 The Cancer Genome Atlas Breast Invasive Carcinoma ADO 0.03 0.02 blup 53 0.03 1.8e-06 6.9 9.8 1.8e-22 0.09 0.02 0.98 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma NRBF2 0.05 0.06 lasso 2 0.06 5.5e-12 9.0 -8.9 8.0e-19 0.89 0.09 0.91 FALSE
21 The Cancer Genome Atlas Glioblastoma Multiforme JMJD1C 0.11 0.02 blup 87 0.05 1.4e-02 9.1 -6.5 6.1e-11 0.79 0.05 0.10 FALSE
22 The Cancer Genome Atlas Glioblastoma Multiforme NRBF2 0.17 0.09 enet 10 0.13 1.1e-04 9.0 -5.8 4.9e-09 0.75 0.09 0.28 FALSE
23 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NRBF2 0.04 0.04 enet 5 0.03 1.3e-04 9.1 -9.9 4.6e-23 0.91 0.02 0.92 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADO 0.10 0.03 enet 6 0.06 4.6e-07 10.2 8.8 1.2e-18 0.04 0.00 1.00 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NRBF2 0.10 0.06 lasso 7 0.08 3.5e-09 -9.5 -10.6 4.4e-26 0.86 0.00 1.00 FALSE
26 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NRBF2 0.08 0.01 blup 40 0.03 6.6e-03 -9.5 -5.3 1.0e-07 0.55 0.00 0.72 TRUE
27 The Cancer Genome Atlas Brain Lower Grade Glioma ADO 0.07 0.06 blup 53 0.05 2.5e-06 10.2 10.6 2.6e-26 0.07 0.00 1.00 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma ARID5B 0.05 0.05 lasso 2 0.04 3.7e-05 -5.7 5.9 3.5e-09 0.03 0.79 0.01 TRUE
29 The Cancer Genome Atlas Brain Lower Grade Glioma NRBF2 0.08 0.08 enet 6 0.08 4.3e-09 9.0 -9.1 1.4e-19 0.90 0.09 0.91 TRUE
30 The Cancer Genome Atlas Brain Lower Grade Glioma REEP3 0.04 0.04 blup 59 0.05 1.8e-06 -9.4 8.7 4.1e-18 -0.80 0.07 0.93 FALSE
31 The Cancer Genome Atlas Lung Adenocarcinoma NRBF2 0.09 0.06 enet 8 0.07 2.7e-08 9.1 -7.2 4.5e-13 0.82 0.08 0.91 TRUE
32 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NRBF2 0.09 0.02 enet 6 0.04 1.4e-05 -3.2 -7.5 6.2e-14 0.74 0.01 0.99 FALSE
33 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADO 0.06 0.04 blup 55 0.01 1.4e-01 -7.2 7.3 3.8e-13 0.10 0.02 0.42 FALSE
34 The Cancer Genome Atlas Pancreatic Adenocarcinoma LOC84989 0.10 0.05 blup 19 0.04 7.7e-03 -3.7 -6.6 5.3e-11 0.67 0.02 0.05 FALSE
35 The Cancer Genome Atlas Pancreatic Adenocarcinoma NRBF2 0.18 0.13 enet 11 0.08 2.5e-04 9.1 -7.3 2.5e-13 0.82 0.07 0.78 TRUE
36 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NRBF2 0.08 0.02 blup 40 0.04 8.6e-03 9.0 -7.4 1.8e-13 0.77 0.02 0.29 FALSE
37 The Cancer Genome Atlas Prostate Adenocarcinoma JMJD1C 0.04 0.01 blup 88 0.01 9.7e-03 9.0 -8.8 1.5e-18 0.80 0.03 0.74 FALSE
38 The Cancer Genome Atlas Prostate Adenocarcinoma NRBF2 0.08 0.09 lasso 6 0.08 9.7e-09 9.1 -9.6 7.3e-22 0.91 0.08 0.92 FALSE
39 The Cancer Genome Atlas Skin Cutaneous Melanoma EGR2 0.12 0.10 blup 56 0.10 1.4e-03 7.7 7.9 3.9e-15 0.03 0.03 0.11 FALSE
40 The Cancer Genome Atlas Thyroid Carcinoma ADO 0.12 0.10 lasso 5 0.09 5.2e-09 -7.2 8.4 3.9e-17 0.08 0.93 0.07 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma NRBF2 0.14 0.10 enet 16 0.09 8.1e-09 9.1 -8.7 4.1e-18 0.86 0.08 0.92 TRUE