[Hub]/) : Traits : Height :

chr11:7,949,791-11,027,552

Best TWAS P=2.16e-18 · Best GWAS P=1.88e-18 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TRIM66 0.09 0.05 bslmm 523 0.05 3.7e-07 5.4 6.5 1.1e-10 0.02 0.99 0.01 TRUE
2 GTEx Adipose Subcutaneous TRIM66 0.52 0.35 enet 42 0.40 3.5e-35 5.4 6.3 2.8e-10 0.04 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous AKIP1 0.08 0.08 lasso 5 0.09 8.1e-08 4.1 5.5 4.9e-08 -0.03 0.04 0.96 FALSE
4 GTEx Adipose Visceral Omentum RP11-152H18.3 0.11 0.04 lasso 3 0.05 1.3e-03 5.2 -5.7 1.3e-08 -0.05 0.36 0.04 FALSE
5 GTEx Adrenal Gland TRIM66 0.23 0.20 lasso 8 0.18 3.3e-07 6.0 6.1 1.3e-09 0.01 0.51 0.14 FALSE
6 GTEx Artery Aorta TRIM66 0.33 0.29 lasso 10 0.30 6.5e-17 5.4 5.1 3.0e-07 0.01 0.99 0.01 FALSE
7 GTEx Artery Coronary TRIM66 0.54 0.34 enet 46 0.43 4.2e-16 5.4 8.8 2.2e-18 0.06 0.99 0.01 TRUE
8 GTEx Artery Tibial TRIM66 0.37 0.22 lasso 7 0.22 2.0e-17 5.2 5.6 2.6e-08 0.05 1.00 0.00 FALSE
9 GTEx Artery Tibial RP11-152H18.3 0.11 0.08 lasso 5 0.05 4.1e-05 6.0 -5.6 1.9e-08 0.00 0.70 0.10 FALSE
10 GTEx Brain Cerebellar Hemisphere SCUBE2 0.37 0.19 enet 32 0.18 1.9e-05 1.8 -5.3 9.9e-08 0.05 0.09 0.14 TRUE
11 GTEx Brain Cortex RP11-152H18.3 0.41 0.04 enet 25 0.11 7.6e-04 5.4 -7.2 6.9e-13 -0.07 0.09 0.34 FALSE
12 GTEx Breast Mammary Tissue RP11-152H18.3 0.16 0.02 enet 10 0.05 1.5e-03 5.2 -5.3 1.1e-07 0.00 0.24 0.05 FALSE
13 GTEx Cells EBV-transformed lymphocytes TRIM66 0.50 0.49 lasso 6 0.48 1.0e-17 5.2 5.3 1.0e-07 0.02 1.00 0.00 FALSE
14 GTEx Cells Transformed fibroblasts TRIM66 0.48 0.32 enet 35 0.34 1.7e-26 5.2 5.8 5.9e-09 0.02 1.00 0.00 FALSE
15 GTEx Colon Sigmoid RP11-152H18.3 0.26 0.06 enet 16 0.11 9.3e-05 5.2 -5.7 1.1e-08 -0.04 0.30 0.05 FALSE
16 GTEx Colon Transverse TRIM66 0.28 0.28 lasso 5 0.30 1.3e-14 5.2 5.9 4.4e-09 0.04 1.00 0.00 TRUE
17 GTEx Esophagus Gastroesophageal Junction TRIM66 0.27 0.15 enet 16 0.30 1.7e-11 -5.8 6.1 1.3e-09 0.03 0.94 0.05 FALSE
18 GTEx Esophagus Gastroesophageal Junction RP11-152H18.3 0.19 0.09 enet 9 0.12 2.8e-05 5.2 -6.0 1.7e-09 0.00 0.68 0.05 FALSE
19 GTEx Esophagus Mucosa TRIM66 0.40 0.44 lasso 9 0.47 5.7e-35 5.4 5.4 6.2e-08 0.02 1.00 0.00 FALSE
20 GTEx Esophagus Muscularis TRIM66 0.40 0.24 lasso 7 0.27 2.1e-16 5.2 6.0 2.6e-09 0.05 1.00 0.00 FALSE
21 GTEx Esophagus Muscularis RP11-152H18.3 0.12 0.05 lasso 6 0.10 8.2e-07 6.0 -5.9 3.6e-09 -0.06 0.60 0.06 TRUE
22 GTEx Heart Atrial Appendage TRIM66 0.39 0.31 lasso 9 0.35 2.8e-16 5.4 5.5 4.3e-08 0.02 0.98 0.02 FALSE
23 GTEx Heart Atrial Appendage RP11-152H18.3 0.27 0.11 lasso 5 0.11 8.9e-06 -5.8 -6.2 4.9e-10 -0.06 0.49 0.09 FALSE
24 GTEx Heart Left Ventricle TRIM66 0.44 0.35 lasso 7 0.35 3.2e-19 5.4 6.0 2.1e-09 0.01 0.98 0.02 FALSE
25 GTEx Lung TRIM66 0.53 0.38 enet 20 0.44 1.2e-36 5.4 5.7 1.1e-08 0.01 0.99 0.01 FALSE
26 GTEx Muscle Skeletal TRIM66 0.38 0.20 lasso 12 0.22 2.7e-21 5.2 5.7 1.5e-08 0.05 1.00 0.00 FALSE
27 GTEx Ovary TRIM66 0.29 0.19 lasso 7 0.22 5.4e-06 5.4 6.0 1.5e-09 0.01 0.18 0.18 FALSE
28 GTEx Pancreas TRIM66 0.33 0.27 lasso 2 0.25 6.8e-11 5.2 5.5 3.0e-08 0.03 0.99 0.00 FALSE
29 GTEx Pancreas AKIP1 0.10 -0.01 enet 14 0.00 4.5e-01 -3.3 6.4 1.2e-10 0.01 0.05 0.51 FALSE
30 GTEx Pituitary AKIP1 0.17 0.07 lasso 5 0.02 8.6e-02 6.3 6.2 4.5e-10 -0.02 0.03 0.68 FALSE
31 GTEx Prostate SBF2 0.21 0.05 lasso 7 0.03 6.7e-02 8.3 7.5 7.9e-14 0.94 0.05 0.70 FALSE
32 GTEx Prostate TRIM66 0.35 0.24 lasso 5 0.30 4.0e-08 6.0 5.6 2.0e-08 0.00 0.47 0.06 FALSE
33 GTEx Skin Not Sun Exposed Suprapubic TRIM66 0.21 0.26 enet 11 0.26 8.9e-15 5.4 5.6 1.8e-08 0.02 0.99 0.01 FALSE
34 GTEx Skin Sun Exposed Lower leg TRIM66 0.44 0.39 lasso 8 0.39 1.9e-34 5.4 5.2 2.2e-07 0.01 1.00 0.00 FALSE
35 GTEx Skin Sun Exposed Lower leg AKIP1 0.05 0.05 enet 8 0.04 1.7e-04 6.2 5.9 2.8e-09 0.01 0.02 0.97 TRUE
36 GTEx Small Intestine Terminal Ileum TRIM66 0.19 0.15 lasso 3 0.21 1.8e-05 5.2 5.1 3.0e-07 0.03 0.22 0.07 FALSE
37 GTEx Stomach TRIM66 0.22 0.20 lasso 5 0.20 8.0e-10 5.2 5.4 5.7e-08 0.01 0.98 0.02 FALSE
38 GTEx Testis SBF2 0.10 0.01 lasso 5 0.02 5.0e-02 8.2 -8.1 4.5e-16 -0.98 0.04 0.89 TRUE
39 GTEx Testis TRIM66 0.33 0.41 lasso 3 0.41 9.1e-20 5.4 5.6 2.4e-08 0.01 0.99 0.01 FALSE
40 GTEx Thyroid TRIM66 0.49 0.36 enet 23 0.42 1.1e-34 5.4 5.5 3.0e-08 0.03 1.00 0.00 FALSE
41 GTEx Whole Blood TRIM66 0.19 0.16 lasso 8 0.15 1.1e-13 5.4 5.8 5.0e-09 0.01 0.99 0.01 FALSE
42 GTEx Whole Blood ST5 0.07 0.08 enet 18 0.05 3.3e-05 5.5 6.9 4.8e-12 -0.04 0.95 0.03 FALSE
43 GTEx Whole Blood RP11-152H18.3 0.04 0.02 lasso 4 0.01 2.0e-02 5.5 5.7 1.5e-08 -0.05 0.68 0.03 FALSE
44 METSIM Adipose TRIM66 0.37 0.30 bslmm 520 0.31 8.6e-48 5.4 5.3 1.2e-07 0.01 1.00 0.00 TRUE
45 NTR Blood ADM 0.04 0.04 enet 13 0.04 1.6e-13 8.3 -7.4 1.7e-13 -0.93 0.02 0.98 FALSE
46 NTR Blood TRIM66 0.07 0.09 enet 3 0.10 2.9e-29 5.2 5.5 2.8e-08 0.01 1.00 0.00 FALSE
47 ROSMAP Brain Pre-frontal Cortex TRIM66 0.06 0.11 lasso 3 0.10 7.0e-13 5.4 5.6 2.3e-08 0.02 1.00 0.00 FALSE
48 ROSMAP Brain Pre-frontal Cortex AKIP1 0.03 0.02 blup 359 0.01 9.0e-03 5.4 6.3 2.6e-10 0.04 0.07 0.85 FALSE
49 ROSMAP Brain Pre-frontal Cortex SBF2-AS1 0.03 0.00 bslmm 362 0.01 4.4e-03 -2.5 7.3 2.9e-13 0.61 0.04 0.62 FALSE
50 YFS Blood ADM 0.08 0.11 enet 25 0.12 9.4e-36 8.2 -7.3 2.9e-13 -0.92 0.02 0.98 FALSE
51 YFS Blood TRIM66 0.53 0.50 bslmm 502 0.51 3.2e-199 5.2 5.7 9.5e-09 0.04 1.00 0.00 FALSE
52 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM66 0.24 0.18 enet 9 0.21 1.5e-17 5.4 5.2 2.0e-07 -0.03 0.01 0.99 TRUE
53 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM66 0.14 0.14 lasso 5 0.15 5.8e-29 5.4 5.2 2.1e-07 0.01 0.05 0.95 FALSE
54 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIM66 0.47 0.30 lasso 4 0.29 9.2e-15 5.4 5.3 1.0e-07 0.02 0.05 0.95 FALSE
55 The Cancer Genome Atlas Colon Adenocarcinoma TRIM66 0.17 0.15 lasso 1 0.12 2.0e-07 5.4 5.4 6.1e-08 0.01 0.03 0.97 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIM66 0.41 0.31 lasso 6 0.32 3.9e-36 5.4 5.3 9.0e-08 0.02 0.03 0.96 FALSE
57 The Cancer Genome Atlas Brain Lower Grade Glioma TRIM66 0.29 0.17 lasso 3 0.16 3.0e-18 5.2 5.4 7.0e-08 0.01 0.04 0.96 FALSE
58 The Cancer Genome Atlas Liver Hepatocellular Carcinoma TRIM66 0.27 0.16 lasso 3 0.14 4.0e-07 5.4 5.3 8.6e-08 0.01 0.04 0.96 FALSE
59 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIM66 0.28 0.22 lasso 5 0.22 1.1e-14 5.4 5.8 8.7e-09 0.01 0.03 0.97 FALSE
60 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ADM 0.08 0.02 blup 36 0.03 1.8e-02 -3.9 5.4 5.8e-08 0.78 0.01 0.62 FALSE
61 The Cancer Genome Atlas Rectum Adenocarcinoma TRIM66 0.50 0.21 lasso 5 0.18 5.6e-05 5.4 5.6 2.1e-08 0.00 0.02 0.84 FALSE
62 The Cancer Genome Atlas Soft Tissue Sarcoma TRIM66 0.28 0.21 lasso 5 0.23 5.4e-14 5.4 5.9 2.8e-09 -0.01 0.00 1.00 FALSE
63 The Cancer Genome Atlas Thyroid Carcinoma TRIM66 0.48 0.49 lasso 9 0.50 4.3e-55 5.2 5.4 6.1e-08 0.02 0.06 0.94 FALSE