[Hub]/) : Traits : Height :

chr1:168,932,500-174,525,917

Best TWAS P=1.73e-66 · Best GWAS P=4.72e-125 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex METTL13 0.23 0.23 bslmm 479 0.27 2.0e-33 3.45 7.1 1.6e-12 0.04 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous PIGC 0.11 0.01 enet 11 0.00 2.8e-01 9.47 8.8 1.4e-18 0.08 0.06 0.03 TRUE
3 GTEx Adrenal Gland METTL18 0.36 0.33 enet 12 0.38 1.4e-14 4.91 -5.2 2.0e-07 0.05 0.17 0.83 FALSE
4 GTEx Artery Coronary METTL18 0.31 0.26 lasso 8 0.20 2.3e-07 5.51 -5.3 1.2e-07 0.04 0.05 0.95 FALSE
5 GTEx Artery Tibial PIGC 0.11 0.00 enet 21 0.01 8.4e-02 -2.28 17.2 1.7e-66 0.27 0.06 0.07 TRUE
6 GTEx Brain Caudate basal ganglia DARS2 0.19 0.02 lasso 5 0.13 1.2e-04 5.11 -5.5 4.0e-08 0.04 0.09 0.57 TRUE
7 GTEx Brain Cerebellum METTL13 0.22 0.00 enet 25 0.05 1.5e-02 3.50 -9.8 8.5e-23 -0.30 0.09 0.43 TRUE
8 GTEx Brain Cerebellum METTL18 0.31 0.36 lasso 7 0.34 8.4e-11 4.80 -5.2 1.5e-07 0.05 0.04 0.96 FALSE
9 GTEx Breast Mammary Tissue (Male) METTL18 0.30 0.14 lasso 6 0.18 6.6e-05 5.14 -5.3 9.8e-08 0.04 0.07 0.90 FALSE
10 GTEx Breast Mammary Tissue (Female) SUCO 0.33 0.00 lasso 9 0.01 1.8e-01 5.16 -7.5 8.0e-14 -0.01 0.08 0.05 TRUE
11 GTEx Cells Transformed fibroblasts PIGC 0.12 0.00 enet 29 0.04 2.7e-04 20.94 -11.3 1.4e-29 -0.40 0.07 0.19 TRUE
12 GTEx Esophagus Gastroesophageal Junction PIGC 0.18 0.08 enet 12 0.13 1.7e-05 0.79 5.5 4.8e-08 0.01 0.21 0.04 TRUE
13 GTEx Esophagus Gastroesophageal Junction METTL18 0.30 0.39 lasso 15 0.39 3.2e-15 4.80 -5.3 1.4e-07 0.05 0.17 0.82 FALSE
14 GTEx Esophagus Muscularis GORAB 0.14 0.08 lasso 2 0.06 1.7e-04 5.34 -5.4 6.8e-08 -0.12 0.43 0.02 FALSE
15 GTEx Heart Left Ventricle GORAB 0.16 0.08 enet 22 0.03 6.9e-03 5.34 -5.7 1.2e-08 -0.11 0.24 0.05 FALSE
16 GTEx Lung GORAB 0.15 0.08 enet 23 0.10 6.2e-08 5.34 -6.8 8.4e-12 -0.07 0.80 0.01 TRUE
17 GTEx Muscle Skeletal SUCO 0.09 0.07 lasso 7 0.07 1.0e-07 -7.07 -7.0 3.7e-12 -0.06 0.99 0.00 TRUE
18 GTEx Nerve Tibial PIGC 0.10 0.02 enet 10 0.02 1.3e-02 -6.88 12.3 1.5e-34 0.21 0.16 0.04 FALSE
19 GTEx Nerve Tibial METTL18 0.22 0.36 lasso 18 0.36 2.8e-26 4.91 -5.1 3.0e-07 0.05 0.22 0.78 FALSE
20 GTEx Ovary METTL18 0.34 0.25 lasso 18 0.24 1.3e-06 4.86 -5.3 1.2e-07 0.06 0.08 0.90 FALSE
21 GTEx Pancreas SUCO 0.17 0.00 enet 15 0.07 5.6e-04 11.03 -6.9 6.9e-12 0.04 0.12 0.06 FALSE
22 GTEx Pituitary METTL18 0.19 0.05 lasso 6 0.10 2.2e-03 5.54 -5.7 1.3e-08 0.07 0.04 0.93 FALSE
23 GTEx Prostate METTL18 0.28 0.24 lasso 8 0.24 1.1e-06 5.51 -5.5 3.3e-08 0.04 0.04 0.95 FALSE
24 GTEx Skin Sun Exposed Lower leg GORAB 0.07 0.01 lasso 5 0.00 4.2e-01 -3.70 -5.8 7.6e-09 0.09 0.09 0.10 FALSE
25 GTEx Skin Sun Exposed Lower leg PIGC 0.08 0.02 lasso 5 0.02 8.8e-03 11.14 11.3 1.6e-29 -0.04 0.52 0.02 FALSE
26 GTEx Spleen PIGC 0.29 0.04 lasso 6 0.07 6.6e-03 7.02 13.3 3.4e-40 0.23 0.06 0.14 FALSE
27 GTEx Stomach METTL18 0.25 0.30 lasso 6 0.33 2.4e-16 4.94 -5.3 1.1e-07 0.05 0.22 0.78 FALSE
28 GTEx Testis C1orf112 0.15 0.04 lasso 9 0.06 8.9e-04 4.94 -5.4 5.9e-08 0.00 0.14 0.78 FALSE
29 GTEx Testis METTL13 0.29 0.05 lasso 10 0.09 9.9e-05 -8.49 15.5 5.4e-54 0.18 0.26 0.04 FALSE
30 GTEx Testis SUCO 0.17 -0.01 enet 39 0.05 2.9e-03 8.42 -5.5 3.2e-08 -0.29 0.06 0.11 FALSE
31 GTEx Thyroid SUCO 0.09 0.08 lasso 1 0.07 8.9e-06 5.16 -5.2 2.5e-07 -0.01 0.93 0.00 TRUE
32 GTEx Thyroid METTL18 0.19 0.31 lasso 16 0.32 3.3e-25 4.91 -5.1 3.0e-07 0.04 0.20 0.79 FALSE
33 GTEx Vagina METTL18 0.26 0.03 enet 46 0.12 8.9e-04 4.81 -6.1 8.5e-10 0.04 0.07 0.78 TRUE
34 GTEx Whole Blood PIGC 0.19 0.10 enet 23 0.12 3.2e-11 11.38 10.9 8.7e-28 0.19 1.00 0.00 TRUE
35 GTEx Whole Blood METTL18 0.08 0.06 lasso 7 0.05 1.1e-05 5.14 -5.1 3.0e-07 0.03 0.13 0.87 FALSE
36 NTR Blood VAMP4 0.01 0.01 lasso 4 0.01 3.8e-03 -4.54 -6.7 1.6e-11 0.00 0.36 0.05 TRUE
37 YFS Blood METTL13 0.11 0.10 bslmm 482 0.10 1.5e-32 3.45 -6.4 1.9e-10 -0.05 1.00 0.00 FALSE
38 The Cancer Genome Atlas Breast Invasive Carcinoma PIGC 0.05 0.00 enet 12 0.02 2.3e-04 -6.74 5.8 4.8e-09 -0.04 0.02 0.02 FALSE
39 The Cancer Genome Atlas Colon Adenocarcinoma C1orf105 0.10 0.01 blup 100 0.04 1.8e-03 11.33 11.9 8.3e-33 0.23 0.01 0.88 FALSE
40 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PIGC 0.10 0.01 blup 94 0.05 1.0e-06 -6.88 9.7 2.7e-22 -0.03 0.13 0.03 TRUE
41 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma METTL13 0.14 0.00 blup 89 0.03 8.0e-03 3.50 -6.8 7.3e-12 -0.07 0.02 0.06 FALSE
42 The Cancer Genome Atlas Brain Lower Grade Glioma ANKRD45 0.14 0.01 lasso 4 0.07 6.9e-08 4.73 5.5 5.1e-08 -0.08 0.00 0.48 FALSE
43 The Cancer Genome Atlas Brain Lower Grade Glioma PIGC 0.09 0.00 blup 94 0.04 2.9e-05 -1.19 9.8 1.8e-22 0.05 0.04 0.53 TRUE
44 The Cancer Genome Atlas Lung Adenocarcinoma PIGC 0.04 0.00 blup 94 0.01 3.2e-02 2.29 -5.3 1.4e-07 -0.37 0.23 0.08 TRUE
45 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma GORAB 0.15 0.07 blup 32 0.09 2.3e-04 5.20 -5.2 1.9e-07 -0.06 0.12 0.04 FALSE
46 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PIGC 0.16 0.06 blup 94 0.07 6.9e-04 5.34 -7.3 3.2e-13 0.12 0.19 0.05 FALSE
47 The Cancer Genome Atlas Thyroid Carcinoma DNM3 0.13 0.08 enet 29 0.10 4.9e-10 -5.43 -6.3 3.3e-10 -0.18 1.00 0.00 TRUE
48 The Cancer Genome Atlas Thyroid Carcinoma PIGC 0.09 0.02 blup 94 0.05 5.2e-06 -2.20 10.4 3.6e-25 0.07 0.18 0.13 TRUE
49 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma VAMP4 0.18 0.02 blup 85 0.05 1.9e-02 -4.74 -5.9 3.3e-09 -0.02 0.08 0.12 TRUE