[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr11:110,526,172-112,794,647

Best TWAS P=2.26e-32 · Best GWAS P=1.41e-32 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PPP2R1B	0.14	0.18	enet	19	0.19	8.3e-23	7.7	9.5	2.2e-21	-0.68	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	PPP2R1B	0.11	0.05	enet	16	0.08	4.4e-07	7.3	9.6	7.2e-22	-0.59	0.27	0.72	FALSE
3	GTEx	Adipose Visceral Omentum	PPP2R1B	0.07	0.00	lasso	9	0.00	2.2e-01	8.3	10.8	2.5e-27	-0.73	0.04	0.90	FALSE
4	GTEx	Artery Aorta	C11orf1	0.10	0.00	enet	10	0.04	1.9e-03	-11.5	-9.8	1.3e-22	0.53	0.06	0.64	FALSE
5	GTEx	Artery Tibial	PPP2R1B	0.14	0.10	lasso	3	0.11	4.9e-09	7.3	8.6	9.7e-18	-0.49	0.99	0.00	FALSE
6	GTEx	Brain Caudate basal ganglia	PPP2R1B	0.27	0.14	lasso	3	0.15	4.8e-05	8.3	10.3	6.9e-25	-0.75	0.02	0.94	FALSE
7	GTEx	Brain Cerebellum	PPP2R1B	0.14	0.14	lasso	4	0.12	1.6e-04	8.3	6.4	1.5e-10	-0.39	0.18	0.08	FALSE
8	GTEx	Brain Cortex	PPP2R1B	0.16	0.07	lasso	2	0.09	1.8e-03	8.3	8.4	6.2e-17	-0.53	0.10	0.45	TRUE
9	GTEx	Brain Frontal Cortex BA9	PPP2R1B	0.27	0.07	lasso	2	0.06	1.3e-02	8.3	8.8	1.5e-18	-0.54	0.06	0.24	FALSE
10	GTEx	Brain Frontal Cortex BA9	PIH1D2	0.30	0.00	enet	32	0.08	2.9e-03	2.3	5.6	2.4e-08	-0.28	0.06	0.26	TRUE
11	GTEx	Brain Nucleus accumbens basal ganglia	PPP2R1B	0.36	0.20	lasso	3	0.17	2.5e-05	8.3	8.4	6.2e-17	-0.56	0.08	0.80	FALSE
12	GTEx	Brain Putamen basal ganglia	PPP2R1B	0.26	0.18	lasso	2	0.14	3.5e-04	8.3	8.3	1.0e-16	-0.57	0.09	0.73	FALSE
13	GTEx	Cells Transformed fibroblasts	PPP2R1B	0.10	0.07	enet	14	0.12	5.5e-09	-9.1	10.9	6.8e-28	-0.87	0.02	0.98	FALSE
14	GTEx	Cells Transformed fibroblasts	DLAT	0.13	0.09	lasso	2	0.08	8.0e-07	-11.7	10.9	1.2e-27	-0.84	0.04	0.96	TRUE
15	GTEx	Esophagus Mucosa	PPP2R1B	0.09	0.09	lasso	1	0.07	1.4e-05	8.2	8.2	1.9e-16	-0.56	0.65	0.14	FALSE
16	GTEx	Esophagus Muscularis	PPP2R1B	0.15	0.04	enet	20	0.04	2.9e-03	8.3	6.8	7.4e-12	-0.50	0.70	0.25	FALSE
17	GTEx	Heart Atrial Appendage	CRYAB	0.13	0.00	lasso	3	-0.01	7.3e-01	1.8	8.6	6.5e-18	-0.59	0.04	0.42	FALSE
18	GTEx	Lung	PPP2R1B	0.12	0.10	lasso	4	0.10	5.6e-08	8.2	8.0	8.8e-16	-0.57	0.68	0.29	TRUE
19	GTEx	Muscle Skeletal	DLAT	0.10	0.07	lasso	4	0.06	3.9e-06	-11.6	11.7	1.4e-31	-0.85	0.04	0.96	FALSE
20	GTEx	Nerve Tibial	PPP2R1B	0.20	0.00	enet	23	0.03	5.9e-03	8.2	6.9	4.1e-12	-0.42	0.27	0.16	FALSE
21	GTEx	Prostate	PPP2R1B	0.18	0.10	lasso	4	0.02	8.2e-02	8.4	9.7	3.7e-22	-0.70	0.04	0.66	FALSE
22	GTEx	Skin Sun Exposed Lower leg	DLAT	0.05	0.03	lasso	3	0.03	1.3e-03	-11.7	-11.7	2.0e-31	0.88	0.05	0.93	FALSE
23	GTEx	Thyroid	PPP2R1B	0.32	0.26	lasso	9	0.26	2.6e-20	8.3	10.4	2.7e-25	-0.70	1.00	0.00	FALSE
24	METSIM	Adipose	BCO2	0.17	0.06	bslmm	390	0.10	5.6e-15	2.0	-6.6	4.7e-11	0.30	1.00	0.00	FALSE
25	METSIM	Adipose	CRYAB	0.03	0.03	blup	323	0.03	3.2e-05	-11.5	-11.8	2.3e-32	0.86	0.06	0.94	TRUE
26	METSIM	Adipose	DIXDC1	0.04	0.01	bslmm	360	0.02	1.4e-03	8.3	-10.2	2.0e-24	0.71	0.09	0.82	FALSE
27	METSIM	Adipose	PPP2R1B	0.20	0.10	enet	26	0.16	1.9e-22	8.4	8.3	1.1e-16	-0.63	0.95	0.05	TRUE
28	NTR	Blood	POU2AF1	0.07	0.05	bslmm	434	0.05	3.2e-16	-3.7	5.5	3.8e-08	-0.15	1.00	0.00	FALSE
29	NTR	Blood	PPP2R1B	0.02	0.01	bslmm	374	0.01	3.2e-05	8.4	9.6	1.2e-21	-0.59	0.25	0.68	FALSE
30	NTR	Blood	SIK2	0.01	0.00	enet	9	0.01	1.3e-04	4.4	6.2	5.9e-10	-0.49	0.06	0.61	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	ALG9	0.02	0.02	enet	9	0.02	1.8e-03	-11.7	11.5	1.5e-30	-0.92	0.01	0.98	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	CRYAB	0.03	0.00	blup	242	0.01	2.3e-02	-11.7	-9.3	1.5e-20	0.81	0.01	0.97	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	PPP2R1B	0.32	0.30	lasso	10	0.36	1.8e-48	7.7	10.0	1.4e-23	-0.66	1.00	0.00	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	C11orf52	0.04	0.03	lasso	2	0.03	1.7e-04	-11.7	-11.7	1.5e-31	0.86	0.01	0.98	FALSE
35	YFS	Blood	DIXDC1	0.07	0.03	blup	353	0.06	2.7e-19	-9.8	-9.0	2.2e-19	0.76	0.02	0.98	FALSE
36	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FDXACB1	0.04	0.03	enet	3	0.04	3.1e-04	-9.7	-10.5	5.9e-26	0.80	0.00	0.88	FALSE
37	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HSPB2	0.03	0.03	lasso	2	0.02	1.6e-03	-9.7	10.2	1.4e-24	-0.81	0.00	0.94	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP2R1B	0.09	0.07	blup	12	0.07	3.3e-08	7.7	6.1	8.9e-10	-0.42	0.96	0.03	FALSE
39	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C11orf1	0.09	0.01	blup	5	0.03	2.0e-02	-9.7	-5.5	3.4e-08	0.64	0.00	0.44	FALSE
40	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ALG9	0.02	0.02	enet	4	0.02	4.3e-03	-9.7	9.9	3.4e-23	-0.89	0.00	0.87	TRUE
41	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LAYN	0.13	0.07	enet	8	0.07	9.9e-04	3.5	6.8	9.4e-12	-0.33	0.03	0.34	FALSE
42	The Cancer Genome Atlas	Soft Tissue Sarcoma	PPP2R1B	0.16	0.06	blup	12	0.06	2.4e-04	7.7	8.6	8.3e-18	-0.56	0.02	0.19	FALSE