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chr20:61,576,647-62,912,463

Best TWAS P=2.82e-11 · Best GWAS P=3.44e-08 conditioned to 0.536

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFRP1 0.07 0.07 lasso 3 0.06 5.3e-08 -5.4 5.6 1.6e-08 -0.89 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex STMN3 0.07 0.02 lasso 4 0.05 2.8e-06 -5.5 -5.3 1.1e-07 0.76 0.02 0.98 FALSE
3 GTEx Brain Cerebellar Hemisphere STMN3 0.39 0.08 lasso 5 0.22 2.1e-06 -4.8 -5.4 5.1e-08 0.62 0.04 0.90 FALSE
4 GTEx Brain Cerebellum STMN3 0.33 0.12 lasso 10 0.20 1.8e-06 -5.2 -5.2 2.3e-07 0.78 0.02 0.97 FALSE
5 GTEx Brain Cortex STMN3 0.25 0.09 lasso 7 0.11 6.8e-04 -5.4 -5.2 1.7e-07 0.92 0.02 0.93 FALSE
6 GTEx Testis RTEL1 0.19 0.06 lasso 5 0.14 8.0e-07 -5.4 -6.7 2.8e-11 0.77 0.02 0.95 TRUE
7 YFS Blood LIME1 0.12 0.19 enet 15 0.19 5.3e-59 -5.2 -5.3 1.1e-07 0.73 0.03 0.97 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma LIME1 0.02 0.03 blup 47 0.02 6.2e-03 -5.4 -5.2 1.9e-07 0.93 0.01 0.86 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma TNFRSF6B 0.02 0.01 enet 7 0.01 6.9e-03 -5.2 -5.6 1.6e-08 0.93 0.02 0.88 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RTEL1 0.05 0.04 blup 56 0.03 4.2e-03 -3.3 -6.0 2.5e-09 0.78 0.02 0.67 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma ARFRP1 0.03 0.02 lasso 2 0.02 1.2e-03 -5.4 5.4 7.5e-08 -0.78 0.02 0.92 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma ZGPAT 0.05 0.06 lasso 3 0.06 5.5e-07 -5.5 5.7 1.4e-08 -0.99 0.01 0.99 FALSE