[Hub]/) : Traits : Blood White Count : ← →

chr1:65,054,671-68,152,438

Best TWAS P=7.24e-35 · Best GWAS P=1.85e-85 conditioned to 1.08e-22

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	ROSMAP	Brain Pre-frontal Cortex	LEPR	0.09	0.07	blup	505	0.06	4.6e-08	8.7	-12.3	7.2e-35	0.29	1.00	0.00	TRUE
1	CommonMind	Brain Pre-frontal Cortex	LEPR	0.07	0.05	enet	15	0.06	5.1e-08	-9.3	-9.3	1.4e-20	0.29	0.98	0.00	TRUE
7	GTEx	Cells Transformed fibroblasts	MIER1	0.19	0.09	lasso	7	0.10	3.1e-08	6.1	7.3	3.8e-13	0.02	0.02	0.98	TRUE
16	NTR	Blood	LEPROT	0.10	0.05	lasso	6	0.09	1.1e-26	9.0	-7.2	5.8e-13	0.24	1.00	0.00	TRUE
23	The Cancer Genome Atlas	Thyroid Carcinoma	LEPR	0.09	0.01	enet	24	0.07	6.1e-07	-9.3	-7.1	1.3e-12	0.16	0.08	0.04	TRUE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LEPR	0.13	0.02	blup	142	0.07	3.9e-08	7.3	-6.9	4.4e-12	0.26	0.44	0.06	TRUE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	JAK1	0.04	0.01	blup	91	0.02	9.2e-03	5.7	-6.8	1.5e-11	0.06	0.01	0.88	TRUE
14	METSIM	Adipose	LEPROT	0.08	0.04	enet	8	0.05	9.3e-08	-3.3	-5.8	6.4e-09	0.15	0.96	0.00	TRUE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDE4B	0.03	0.00	blup	320	0.01	3.5e-02	7.2	5.5	3.7e-08	-0.16	0.18	0.02	TRUE
12	GTEx	Whole Blood	TCTEX1D1	0.05	0.01	enet	10	0.02	9.9e-03	-2.5	-5.4	6.1e-08	0.02	0.23	0.04	TRUE
13	METSIM	Adipose	LEPR	0.16	0.08	bslmm	540	0.09	4.1e-13	9.0	-5.3	1.4e-07	0.04	1.00	0.00	TRUE
18	YFS	Blood	LEPROT	0.40	0.25	enet	52	0.38	2.0e-133	8.8	-7.5	9.0e-14	0.22	1.00	0.00	FALSE
8	GTEx	Esophagus Muscularis	MIER1	0.14	0.05	enet	9	0.04	2.5e-03	6.4	6.6	3.1e-11	0.01	0.09	0.78	FALSE
10	GTEx	Testis	WDR78	0.45	0.42	lasso	6	0.40	5.0e-19	6.4	6.5	1.0e-10	0.02	0.98	0.02	FALSE
11	GTEx	Thyroid	WDR78	0.12	0.11	lasso	3	0.09	2.4e-07	6.2	-6.3	3.0e-10	-0.03	0.97	0.02	FALSE
15	METSIM	Adipose	MIER1	0.05	0.05	enet	19	0.04	2.8e-07	6.1	6.2	4.3e-10	0.01	0.20	0.80	FALSE
4	GTEx	Artery Tibial	MIER1	0.12	0.08	lasso	4	0.07	6.3e-06	6.2	6.2	7.4e-10	0.02	0.87	0.11	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	SLC35D1	0.13	0.10	enet	16	0.20	9.2e-19	7.7	6.1	9.5e-10	0.00	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	WDR78	0.13	0.14	lasso	3	0.14	1.7e-16	6.1	-6.1	9.9e-10	0.00	0.03	0.97	FALSE
5	GTEx	Breast Mammary Tissue	MIER1	0.12	0.07	lasso	2	0.05	8.5e-04	6.1	6.1	1.1e-09	0.03	0.20	0.48	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	JAK1	0.08	0.06	enet	9	0.06	2.0e-06	5.9	-6.1	1.2e-09	0.06	0.01	0.99	FALSE
6	GTEx	Breast Mammary Tissue (Female)	MIER1	0.21	-0.01	lasso	6	0.00	4.3e-01	6.1	6.0	2.2e-09	0.01	0.05	0.51	FALSE
9	GTEx	Nerve Tibial	WDR78	0.13	0.07	lasso	5	0.06	7.5e-05	6.4	-5.8	6.1e-09	-0.03	0.74	0.12	FALSE
3	GTEx	Artery Tibial	WDR78	0.14	0.09	lasso	8	0.09	2.1e-07	6.4	-5.8	8.4e-09	-0.05	0.95	0.04	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	TCTEX1D1	0.03	0.00	blup	72	0.01	4.5e-02	3.6	-5.2	2.1e-07	-0.01	0.01	0.72	FALSE