[Hub]/) : Traits : Blood White Count : ← →

chr1:44,790,653-47,573,980

Best TWAS P=3.01e-21 · Best GWAS P=8.97e-19 conditioned to 0.253

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
40	GTEx	Heart Atrial Appendage	MAST2	0.22	0.07	lasso	15	0.12	5.3e-06	8.6	-9.5	3.0e-21	-0.88	0.04	0.96	TRUE
49	GTEx	Nerve Tibial	MAST2	0.08	0.05	lasso	4	0.06	5.6e-05	-7.9	-9.3	2.1e-20	-0.81	0.06	0.92	FALSE
8	GTEx	Artery Aorta	TMEM69	0.09	0.02	enet	9	0.03	6.4e-03	-6.2	-8.4	3.6e-17	-0.76	0.19	0.70	FALSE
41	GTEx	Heart Left Ventricle	MAST2	0.21	0.08	lasso	7	0.10	5.5e-06	-6.2	-8.4	4.6e-17	-0.81	0.06	0.93	FALSE
26	GTEx	Cells Transformed fibroblasts	MAST2	0.25	0.33	enet	16	0.30	1.0e-22	-7.9	-8.2	3.0e-16	-0.55	0.88	0.12	FALSE
30	GTEx	Cells Transformed fibroblasts	TMEM69	0.10	0.07	enet	10	0.07	3.0e-06	8.8	-8.1	5.3e-16	-0.90	0.01	0.99	FALSE
44	GTEx	Lung	MAST2	0.06	0.06	lasso	5	0.05	1.7e-04	-7.9	-8.1	6.2e-16	-0.60	0.78	0.19	FALSE
2	GTEx	Adipose Subcutaneous	MAST2	0.09	0.09	lasso	4	0.08	2.6e-07	-7.9	-8.1	6.4e-16	-0.62	0.84	0.16	FALSE
7	GTEx	Artery Aorta	MAST2	0.26	0.32	lasso	16	0.31	2.0e-17	-8.0	-8.1	7.0e-16	-0.57	0.80	0.20	FALSE
74	NTR	Blood	PIK3R3	0.01	0.02	lasso	2	0.02	4.5e-06	-8.1	-8.0	1.3e-15	-0.55	0.82	0.17	FALSE
64	GTEx	Thyroid	IPP	0.08	0.07	lasso	3	0.08	7.1e-07	-8.0	-8.0	1.5e-15	-0.54	0.81	0.18	FALSE
66	GTEx	Uterus	MAST2	0.30	0.28	lasso	2	0.18	2.0e-04	-7.9	-7.9	2.6e-15	-0.57	0.53	0.23	FALSE
12	GTEx	Artery Tibial	MAST2	0.29	0.30	lasso	2	0.30	1.8e-23	-7.9	-7.9	3.6e-15	-0.55	0.91	0.09	FALSE
42	GTEx	Heart Left Ventricle	CCDC163P	0.44	0.51	enet	41	0.54	3.1e-33	6.3	7.7	1.7e-14	0.74	1.00	0.00	FALSE
34	GTEx	Colon Transverse	MAST2	0.18	0.09	lasso	7	0.07	4.5e-04	-7.8	-7.6	2.2e-14	-0.59	0.32	0.58	FALSE
10	GTEx	Artery Coronary	MAST2	0.09	0.09	lasso	4	0.08	1.3e-03	-8.0	-7.4	1.2e-13	-0.55	0.46	0.15	FALSE
32	GTEx	Colon Sigmoid	MAST2	0.18	0.10	lasso	4	0.13	2.5e-05	-7.9	-7.1	1.6e-12	-0.42	0.78	0.16	FALSE
48	GTEx	Muscle Skeletal	CCDC163P	0.29	0.42	enet	29	0.43	2.8e-45	6.3	7.0	2.0e-12	0.74	1.00	0.00	FALSE
38	GTEx	Esophagus Muscularis	MAST2	0.17	0.13	enet	30	0.11	3.8e-07	-8.0	-7.0	2.4e-12	-0.53	0.80	0.20	FALSE
55	GTEx	Pancreas	CCDC163P	0.44	0.57	lasso	12	0.56	8.6e-28	6.2	7.0	2.7e-12	0.64	1.00	0.00	FALSE
71	METSIM	Adipose	CCDC17	0.03	0.02	blup	287	0.01	5.6e-03	-8.0	-7.0	2.9e-12	-0.34	0.36	0.16	FALSE
72	METSIM	Adipose	MAST2	0.06	0.06	lasso	6	0.05	1.3e-08	-7.9	-7.0	3.6e-12	-0.44	0.85	0.15	FALSE
100	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CCDC163P	0.29	0.03	lasso	3	0.04	3.1e-02	6.3	6.9	7.0e-12	0.75	0.01	0.61	FALSE
89	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CCDC163P	0.08	0.05	blup	37	0.04	5.0e-03	6.3	6.8	7.2e-12	0.68	0.02	0.90	FALSE
23	GTEx	Breast Mammary Tissue (Male)	CCDC163P	0.48	0.54	enet	21	0.52	5.5e-14	6.3	6.8	1.1e-11	0.70	0.82	0.18	FALSE
88	The Cancer Genome Atlas	Brain Lower Grade Glioma	MMACHC	0.06	0.02	enet	9	0.05	2.7e-06	6.3	-6.7	1.6e-11	-0.58	0.03	0.97	FALSE
5	GTEx	Adipose Visceral Omentum	CCDC163P	0.43	0.50	lasso	6	0.52	6.1e-31	6.2	6.7	2.1e-11	0.65	1.00	0.00	FALSE
36	GTEx	Esophagus Gastroesophageal Junction	CCDC163P	0.65	0.62	enet	14	0.63	1.3e-28	6.2	6.7	2.6e-11	0.62	1.00	0.00	FALSE
25	GTEx	Cells EBV-transformed lymphocytes	CCDC163P	0.52	0.56	enet	22	0.60	6.4e-24	6.3	6.6	3.3e-11	0.60	1.00	0.00	FALSE
16	GTEx	Brain Cerebellar Hemisphere	CCDC163P	0.58	0.60	lasso	7	0.65	1.7e-21	6.2	6.6	3.5e-11	0.69	0.99	0.01	FALSE
19	GTEx	Brain Frontal Cortex BA9	CCDC163P	0.58	0.47	lasso	8	0.45	1.5e-13	6.3	6.6	3.7e-11	0.67	1.00	0.00	FALSE
65	GTEx	Thyroid	CCDC163P	0.62	0.68	lasso	10	0.71	6.1e-77	6.2	6.6	4.0e-11	0.69	1.00	0.00	FALSE
67	GTEx	Uterus	CCDC163P	0.58	0.45	lasso	9	0.41	1.8e-09	6.4	6.6	4.1e-11	0.69	0.61	0.32	FALSE
56	GTEx	Pituitary	CCDC163P	0.68	0.70	lasso	8	0.70	9.7e-24	6.3	6.5	5.9e-11	0.65	1.00	0.00	FALSE
62	GTEx	Stomach	CCDC163P	0.58	0.61	lasso	6	0.63	6.5e-38	6.2	6.5	5.9e-11	0.64	1.00	0.00	FALSE
98	The Cancer Genome Atlas	Rectum Adenocarcinoma	CCDC163P	0.21	0.17	enet	13	0.14	4.1e-04	6.4	6.5	8.3e-11	0.69	0.02	0.88	FALSE
103	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CCDC163P	0.09	0.03	blup	36	0.06	3.4e-03	6.2	6.5	8.5e-11	0.58	0.02	0.65	FALSE
70	METSIM	Adipose	CCDC163P	0.38	0.37	lasso	7	0.37	2.9e-58	6.3	6.5	9.3e-11	0.67	1.00	0.00	FALSE
104	The Cancer Genome Atlas	Thyroid Carcinoma	CCDC163P	0.38	0.64	enet	20	0.64	4.6e-82	6.2	6.5	1.0e-10	0.64	0.04	0.96	FALSE
21	GTEx	Brain Putamen basal ganglia	CCDC163P	0.43	0.47	lasso	7	0.48	3.7e-13	6.3	6.5	1.1e-10	0.65	0.92	0.08	FALSE
22	GTEx	Breast Mammary Tissue	CCDC163P	0.45	0.61	lasso	9	0.60	1.8e-37	6.3	6.5	1.1e-10	0.66	1.00	0.00	FALSE
101	The Cancer Genome Atlas	Stomach Adenocarcinoma	CCDC163P	0.10	0.12	blup	36	0.12	7.5e-09	6.2	6.5	1.1e-10	0.63	0.04	0.96	FALSE
17	GTEx	Brain Cerebellum	CCDC163P	0.73	0.67	lasso	8	0.70	7.4e-28	6.2	6.4	1.2e-10	0.66	1.00	0.00	FALSE
78	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CCDC163P	0.34	0.38	lasso	7	0.37	2.0e-32	6.3	6.4	1.2e-10	0.67	0.04	0.96	FALSE
86	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TESK2	0.02	0.01	blup	82	0.02	2.0e-03	-3.5	6.4	1.6e-10	0.52	0.06	0.69	FALSE
50	GTEx	Nerve Tibial	IPP	0.07	0.04	enet	12	0.05	1.9e-04	-6.2	-6.4	1.8e-10	-0.31	0.59	0.14	FALSE
91	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CCDC163P	0.27	0.40	enet	9	0.40	3.2e-49	6.3	6.4	1.8e-10	0.63	0.04	0.96	FALSE
37	GTEx	Esophagus Mucosa	CCDC163P	0.59	0.69	enet	18	0.68	8.2e-62	6.3	6.4	1.9e-10	0.63	1.00	0.00	FALSE
57	GTEx	Prostate	CCDC163P	0.77	0.70	lasso	11	0.68	5.1e-23	6.3	6.4	1.9e-10	0.63	1.00	0.00	FALSE
73	NTR	Blood	CCDC163P	0.05	0.07	lasso	7	0.06	5.6e-20	6.2	6.4	2.0e-10	0.62	1.00	0.00	FALSE
106	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CCDC163P	0.11	0.06	blup	37	0.07	5.2e-03	6.2	6.4	2.0e-10	0.67	0.01	0.66	FALSE
18	GTEx	Brain Cortex	CCDC163P	0.34	0.45	enet	14	0.44	1.3e-13	6.3	6.3	2.2e-10	0.60	1.00	0.00	FALSE
59	GTEx	Skin Sun Exposed Lower leg	CCDC163P	0.68	0.73	enet	30	0.74	3.0e-90	6.2	6.3	2.2e-10	0.69	1.00	0.00	FALSE
83	The Cancer Genome Atlas	Glioblastoma Multiforme	CCDC163P	0.21	0.13	lasso	3	0.11	3.0e-04	6.3	6.3	2.2e-10	0.64	0.02	0.82	FALSE
85	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC163P	0.29	0.50	lasso	3	0.49	1.8e-62	6.3	6.3	2.2e-10	0.64	0.03	0.97	FALSE
95	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CCDC163P	0.42	0.48	lasso	7	0.47	3.2e-22	6.2	6.3	2.3e-10	0.62	0.05	0.95	FALSE
11	GTEx	Artery Coronary	CCDC163P	0.72	0.76	lasso	9	0.76	1.6e-37	6.2	6.3	2.4e-10	0.64	1.00	0.00	FALSE
46	GTEx	Lung	CCDC163P	0.56	0.70	lasso	7	0.70	1.6e-74	6.2	6.3	2.4e-10	0.64	1.00	0.00	FALSE
6	GTEx	Adrenal Gland	CCDC163P	0.54	0.61	lasso	6	0.60	1.2e-26	6.3	6.3	2.6e-10	0.64	1.00	0.00	FALSE
15	GTEx	Brain Caudate basal ganglia	CCDC163P	0.54	0.47	lasso	4	0.48	9.8e-16	6.3	6.3	2.6e-10	0.63	1.00	0.00	FALSE
35	GTEx	Colon Transverse	CCDC163P	0.65	0.61	lasso	11	0.60	7.2e-35	6.2	6.3	2.7e-10	0.64	1.00	0.00	FALSE
39	GTEx	Esophagus Muscularis	CCDC163P	0.65	0.72	lasso	8	0.72	6.7e-62	6.2	6.3	3.0e-10	0.64	1.00	0.00	FALSE
51	GTEx	Nerve Tibial	CCDC163P	0.68	0.71	lasso	6	0.73	1.6e-73	6.2	6.3	3.1e-10	0.65	1.00	0.00	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	CCDC163P	0.53	0.64	bslmm	278	0.64	9.6e-107	6.2	6.3	3.1e-10	0.66	1.00	0.00	FALSE
61	GTEx	Spleen	CCDC163P	0.83	0.72	lasso	8	0.75	1.3e-27	6.2	6.3	3.2e-10	0.64	1.00	0.00	FALSE
14	GTEx	Artery Tibial	CCDC163P	0.67	0.75	lasso	7	0.75	5.8e-87	6.2	6.3	3.3e-10	0.64	1.00	0.00	FALSE
52	GTEx	Ovary	CCDC163P	0.57	0.53	lasso	7	0.54	1.5e-15	6.4	6.3	3.3e-10	0.64	0.97	0.03	FALSE
81	The Cancer Genome Atlas	Colon Adenocarcinoma	CCDC163P	0.15	0.24	lasso	10	0.22	3.4e-13	6.2	6.3	3.3e-10	0.62	0.03	0.97	FALSE
58	GTEx	Skin Not Sun Exposed Suprapubic	CCDC163P	0.71	0.76	lasso	7	0.77	3.6e-64	6.2	6.3	3.4e-10	0.64	1.00	0.00	FALSE
63	GTEx	Testis	CCDC163P	0.61	0.64	lasso	9	0.63	6.3e-35	6.2	6.3	3.5e-10	0.63	1.00	0.00	FALSE
77	YFS	Blood	TMEM69	0.02	0.01	bslmm	294	0.01	2.1e-04	-2.9	-6.3	3.5e-10	-0.57	0.25	0.43	FALSE
33	GTEx	Colon Sigmoid	CCDC163P	0.55	0.62	lasso	5	0.64	1.7e-28	6.2	6.3	3.7e-10	0.63	1.00	0.00	FALSE
93	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CCDC163P	0.29	0.48	lasso	6	0.48	2.3e-36	6.2	6.3	3.9e-10	0.63	0.04	0.96	FALSE
43	GTEx	Liver	CCDC163P	0.36	0.47	lasso	5	0.47	6.5e-15	6.3	6.2	4.1e-10	0.64	0.97	0.03	FALSE
102	The Cancer Genome Atlas	Stomach Adenocarcinoma	TMEM69	0.10	0.05	lasso	2	0.04	5.9e-04	-6.2	-6.2	4.1e-10	-0.49	0.18	0.32	FALSE
68	GTEx	Vagina	CCDC163P	0.62	0.66	lasso	4	0.67	2.4e-20	6.2	6.2	4.2e-10	0.63	1.00	0.00	FALSE
69	GTEx	Whole Blood	CCDC163P	0.40	0.51	lasso	6	0.51	9.3e-54	6.2	6.2	4.4e-10	0.63	1.00	0.00	FALSE
80	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CCDC163P	0.31	0.36	enet	14	0.36	9.7e-19	6.2	6.2	4.5e-10	0.63	0.04	0.96	FALSE
9	GTEx	Artery Aorta	CCDC163P	0.73	0.74	lasso	6	0.74	2.1e-59	6.2	6.2	4.6e-10	0.63	1.00	0.00	FALSE
97	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC163P	0.37	0.62	lasso	6	0.62	7.9e-82	6.2	6.2	4.6e-10	0.63	0.04	0.96	FALSE
31	GTEx	Cells Transformed fibroblasts	CCDC163P	0.55	0.62	lasso	4	0.62	1.1e-58	6.2	6.2	5.0e-10	0.63	1.00	0.00	FALSE
84	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC163P	0.19	0.38	lasso	3	0.36	9.1e-43	6.2	6.2	5.3e-10	0.63	0.05	0.95	FALSE
87	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CCDC163P	0.32	0.51	lasso	7	0.51	1.2e-33	6.2	6.2	5.3e-10	0.65	0.03	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCDC163P	0.30	0.36	lasso	2	0.35	8.1e-45	6.2	6.2	5.7e-10	0.63	1.00	0.00	FALSE
4	GTEx	Adipose Subcutaneous	CCDC163P	0.66	0.72	lasso	7	0.73	8.2e-86	6.2	6.2	5.9e-10	0.64	1.00	0.00	FALSE
20	GTEx	Brain Nucleus accumbens basal ganglia	CCDC163P	0.36	0.36	lasso	4	0.36	1.2e-10	6.3	6.2	6.0e-10	0.63	0.91	0.07	FALSE
53	GTEx	Pancreas	TESK2	0.14	0.07	lasso	2	0.07	5.7e-04	5.9	6.2	6.5e-10	0.41	0.57	0.05	FALSE
82	The Cancer Genome Atlas	Esophageal Carcinoma	CCDC163P	0.33	0.32	lasso	8	0.31	1.1e-10	6.2	6.2	6.8e-10	0.63	0.03	0.97	FALSE
90	The Cancer Genome Atlas	Lung Adenocarcinoma	CCDC163P	0.26	0.41	lasso	8	0.41	3.5e-51	6.2	6.1	8.5e-10	0.61	0.04	0.96	FALSE
24	GTEx	Cells EBV-transformed lymphocytes	TESK2	0.15	0.10	lasso	5	0.10	4.5e-04	5.6	6.1	1.0e-09	0.36	0.40	0.27	FALSE
27	GTEx	Cells Transformed fibroblasts	FAAH	0.20	0.06	enet	27	0.14	8.6e-11	2.8	6.1	1.4e-09	0.58	0.04	0.95	FALSE
96	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCDC163P	0.17	0.11	blup	37	0.14	4.4e-06	6.2	6.0	1.4e-09	0.63	0.03	0.97	FALSE
79	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC163P	0.27	0.43	enet	16	0.43	1.2e-97	6.3	6.0	2.0e-09	0.62	0.04	0.96	FALSE
47	GTEx	Muscle Skeletal	RP11-767N6.7	0.06	0.06	lasso	3	0.04	6.6e-05	-6.3	-6.0	2.6e-09	-0.45	0.79	0.01	FALSE
75	ROSMAP	Brain Pre-frontal Cortex	PIK3R3	0.05	0.02	lasso	4	0.03	4.4e-05	6.1	-6.0	2.7e-09	-0.59	0.29	0.53	FALSE
28	GTEx	Cells Transformed fibroblasts	MMACHC	0.09	0.04	lasso	3	0.08	1.5e-06	-3.5	-5.9	3.5e-09	-0.49	0.75	0.10	FALSE
99	The Cancer Genome Atlas	Soft Tissue Sarcoma	CCDC163P	0.16	0.17	blup	37	0.19	2.1e-11	6.4	5.9	3.7e-09	0.50	0.03	0.97	FALSE
45	GTEx	Lung	PRDX1	0.07	0.06	enet	16	0.05	5.3e-05	-3.5	5.8	4.8e-09	0.54	0.41	0.49	FALSE
60	GTEx	Small Intestine Terminal Ileum	CCDC163P	0.63	0.40	enet	35	0.42	1.7e-10	6.3	5.8	5.8e-09	0.49	0.94	0.01	FALSE
105	The Cancer Genome Atlas	Thyroid Carcinoma	PRDX1	0.18	0.20	lasso	6	0.28	7.9e-27	-3.4	5.8	8.0e-09	0.55	0.30	0.70	FALSE
29	GTEx	Cells Transformed fibroblasts	GPBP1L1	0.05	0.02	enet	21	0.02	1.1e-02	-8.0	-5.6	1.8e-08	-0.19	0.51	0.06	FALSE
54	GTEx	Pancreas	ZSWIM5	0.14	0.02	lasso	3	0.03	1.4e-02	4.0	5.5	3.7e-08	0.15	0.23	0.04	FALSE
3	GTEx	Adipose Subcutaneous	GPBP1L1	0.05	0.05	lasso	4	0.05	8.7e-05	-7.7	-5.5	4.2e-08	-0.32	0.83	0.04	FALSE
92	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MMACHC	0.06	0.02	enet	14	0.04	5.5e-05	6.3	5.4	6.7e-08	0.51	0.04	0.91	FALSE
94	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MMACHC	0.07	0.02	blup	41	0.03	4.2e-03	-3.2	5.2	1.6e-07	0.50	0.04	0.76	FALSE
13	GTEx	Artery Tibial	GPBP1L1	0.04	0.04	enet	7	0.03	2.2e-03	4.7	-5.2	2.0e-07	-0.31	0.73	0.08	FALSE