[Hub]/) : Traits : Blood White Count :

chr7:43,924,401-45,801,046

Best TWAS P=8.12e-36 · Best GWAS P=1.98e-47 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex H2AFV 0.14 0.08 lasso 8 0.08 1.8e-10 -6.78 8.1 7.0e-16 -0.19 1.00 0.00 TRUE
2 CommonMind Brain Pre-frontal Cortex NACAD 0.05 0.01 blup 436 0.01 7.8e-03 -3.59 -6.1 1.0e-09 0.45 0.26 0.07 FALSE
3 CommonMind Brain Pre-frontal Cortex TBRG4 0.23 0.21 enet 27 0.22 5.6e-27 -8.35 -9.0 2.4e-19 0.56 1.00 0.00 TRUE
4 GTEx Adipose Subcutaneous TBRG4 0.13 0.08 lasso 2 0.04 2.5e-04 -5.25 -5.3 1.1e-07 0.44 0.78 0.10 FALSE
5 GTEx Adipose Visceral Omentum SNORA5C 0.25 -0.01 lasso 8 0.00 3.2e-01 -0.67 -5.1 2.8e-07 0.32 0.06 0.06 FALSE
6 GTEx Artery Aorta H2AFV 0.10 0.08 lasso 2 0.06 1.9e-04 5.24 5.2 1.6e-07 -0.21 0.43 0.05 FALSE
7 GTEx Artery Aorta TBRG4 0.19 0.01 enet 21 0.03 1.1e-02 -6.42 -7.4 1.4e-13 0.52 0.05 0.48 FALSE
8 GTEx Artery Tibial TBRG4 0.11 0.06 enet 12 0.08 1.6e-06 -5.25 -7.8 4.8e-15 0.58 0.40 0.58 FALSE
9 GTEx Brain Hypothalamus TMED4 0.37 -0.01 enet 36 -0.01 6.3e-01 -8.01 6.1 1.2e-09 -0.15 0.04 0.05 FALSE
10 GTEx Cells EBV-transformed lymphocytes TBRG4 0.42 0.26 lasso 9 0.30 2.1e-10 -8.35 -7.8 7.3e-15 0.56 0.63 0.27 FALSE
11 GTEx Cells Transformed fibroblasts ZMIZ2 0.12 0.09 lasso 4 0.06 2.3e-05 -5.28 -5.7 1.0e-08 0.02 0.84 0.02 FALSE
12 GTEx Cells Transformed fibroblasts TBRG4 0.13 0.13 lasso 1 0.12 5.7e-09 -8.35 -8.3 7.1e-17 0.59 0.99 0.00 FALSE
13 GTEx Cells Transformed fibroblasts NACAD 0.13 0.11 lasso 9 0.11 1.2e-08 -6.77 7.2 8.2e-13 -0.56 0.69 0.31 TRUE
14 GTEx Esophagus Mucosa TBRG4 0.12 0.07 lasso 9 0.08 3.6e-06 -8.35 -10.2 3.1e-24 0.72 0.08 0.92 FALSE
15 GTEx Lung TBRG4 0.11 0.08 lasso 4 0.08 6.4e-07 -5.33 -5.6 1.8e-08 0.47 0.93 0.06 FALSE
16 GTEx Lung NACAD 0.07 0.02 lasso 4 0.02 1.1e-02 -6.42 7.8 7.6e-15 -0.59 0.10 0.28 FALSE
17 GTEx Lung CCM2 0.10 0.06 lasso 6 0.04 3.6e-04 -6.77 -5.2 1.5e-07 0.43 0.72 0.05 TRUE
18 GTEx Muscle Skeletal CCM2 0.09 0.09 lasso 2 0.06 7.3e-07 -6.60 -6.5 9.1e-11 0.51 1.00 0.00 FALSE
19 GTEx Nerve Tibial TBRG4 0.13 0.14 lasso 1 0.12 5.6e-09 -5.25 -5.2 1.5e-07 0.44 1.00 0.00 FALSE
20 GTEx Spleen TBRG4 0.35 0.00 enet 37 0.01 2.1e-01 -8.35 -5.6 1.7e-08 0.51 0.05 0.31 FALSE
21 GTEx Testis H2AFV 0.22 0.06 lasso 4 0.05 3.2e-03 -6.78 -7.3 2.3e-13 0.18 0.35 0.03 FALSE
22 GTEx Testis TBRG4 0.32 0.27 enet 13 0.21 8.7e-10 -5.25 -5.2 2.5e-07 0.39 1.00 0.00 FALSE
23 GTEx Testis SNHG15 0.26 0.13 enet 17 0.18 2.0e-08 -12.06 11.0 6.1e-28 -0.71 0.04 0.96 FALSE
24 GTEx Thyroid H2AFV 0.15 0.04 lasso 6 0.08 1.8e-06 5.24 6.1 1.2e-09 -0.18 0.43 0.02 FALSE
25 GTEx Thyroid TBRG4 0.15 0.06 enet 14 0.08 9.1e-07 -5.33 -9.4 6.7e-21 0.72 0.86 0.14 FALSE
26 METSIM Adipose OGDH 0.04 0.00 blup 443 0.01 8.2e-03 -1.10 5.4 7.1e-08 -0.44 0.17 0.33 FALSE
27 METSIM Adipose TBRG4 0.05 0.04 lasso 2 0.04 3.1e-06 -8.35 -8.3 7.1e-17 0.59 0.83 0.15 FALSE
28 NTR Blood ZMIZ2 0.08 0.06 enet 17 0.06 1.5e-18 8.19 -7.3 2.5e-13 0.17 1.00 0.00 FALSE
29 ROSMAP Brain Pre-frontal Cortex TBRG4 0.18 0.19 lasso 6 0.22 3.8e-27 -5.25 -7.9 3.6e-15 0.58 1.00 0.00 FALSE
30 The Cancer Genome Atlas Breast Invasive Carcinoma NACAD 0.02 0.02 blup 56 0.00 1.1e-01 -5.36 6.7 1.6e-11 -0.52 0.08 0.21 FALSE
31 The Cancer Genome Atlas Breast Invasive Carcinoma TBRG4 0.03 0.03 lasso 3 0.02 1.2e-05 -8.35 -8.2 3.1e-16 0.59 0.15 0.81 TRUE
32 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C7orf40 0.03 0.02 enet 4 0.02 2.4e-03 -13.26 12.5 8.1e-36 -0.89 0.02 0.41 TRUE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TBRG4 0.05 0.01 blup 61 0.03 6.8e-04 -3.59 -8.5 1.6e-17 0.63 0.10 0.71 FALSE
34 The Cancer Genome Atlas Brain Lower Grade Glioma PPIA 0.05 0.02 enet 5 0.03 7.7e-05 -6.37 -5.5 4.9e-08 -0.05 0.02 0.72 FALSE
35 The Cancer Genome Atlas Lung Adenocarcinoma C7orf40 0.04 0.03 blup 29 0.02 1.9e-03 2.75 7.7 2.1e-14 -0.43 0.14 0.07 FALSE
36 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C7orf40 0.07 0.00 blup 29 0.01 9.0e-03 2.75 8.1 6.6e-16 -0.52 0.03 0.18 FALSE
37 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TBRG4 0.08 0.03 blup 61 0.03 7.5e-05 -8.35 -8.3 9.2e-17 0.57 0.03 0.82 FALSE
38 The Cancer Genome Atlas Prostate Adenocarcinoma C7orf40 0.15 0.05 blup 29 0.08 1.6e-08 2.85 7.1 1.1e-12 -0.41 1.00 0.00 FALSE
39 The Cancer Genome Atlas Prostate Adenocarcinoma TBRG4 0.08 0.09 lasso 6 0.10 1.5e-10 -8.35 -7.4 1.3e-13 0.56 1.00 0.00 FALSE
40 The Cancer Genome Atlas Thyroid Carcinoma H2AFV 0.15 0.14 lasso 3 0.14 1.3e-13 5.24 5.8 6.7e-09 -0.21 0.89 0.11 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma TBRG4 0.09 0.09 blup 61 0.09 3.2e-09 -8.35 -10.2 3.0e-24 0.75 0.23 0.77 FALSE
42 The Cancer Genome Atlas Thyroid Carcinoma ZMIZ2 0.06 0.03 blup 35 0.03 3.8e-04 5.13 7.4 1.5e-13 -0.16 0.02 0.97 FALSE