[Hub]/) : Traits : Blood White Count : ← →

chr9:34,967,273-36,556,091

Best TWAS P=7.68e-18 · Best GWAS P=1.65e-15 conditioned to 0.115

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	GTEx	Muscle Skeletal	TPM2	0.06	0.02	lasso	5	0.02	6.2e-03	7.9	8.6	7.7e-18	0.82	0.01	0.98	TRUE
6	GTEx	Brain Cerebellum	TPM2	0.63	0.43	lasso	4	0.53	4.0e-18	8.0	-8.1	7.2e-16	-0.98	0.00	1.00	FALSE
5	GTEx	Brain Cerebellar Hemisphere	TPM2	0.56	0.55	lasso	3	0.56	2.7e-17	8.0	-8.0	1.1e-15	-1.00	0.00	1.00	FALSE
22	NTR	Blood	TPM2	0.04	0.04	lasso	4	0.04	2.3e-13	7.8	-8.0	1.2e-15	-0.98	0.00	1.00	FALSE
16	GTEx	Pancreas	TPM2	0.11	0.15	lasso	2	0.14	1.8e-06	8.0	-8.0	1.5e-15	-1.00	0.00	0.99	FALSE
25	YFS	Blood	TPM2	0.46	0.50	enet	22	0.50	1.1e-194	8.0	-7.8	5.5e-15	-0.98	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	GBA2	0.07	0.03	blup	44	0.03	1.1e-02	-4.0	-7.7	1.9e-14	-0.63	0.03	0.26	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	TPM2	0.55	0.60	enet	21	0.61	1.1e-100	7.9	-7.6	3.1e-14	-0.99	0.00	1.00	FALSE
9	GTEx	Brain Nucleus accumbens basal ganglia	TPM2	0.29	0.30	lasso	8	0.29	2.0e-08	8.0	-7.3	2.9e-13	-0.98	0.00	1.00	FALSE
20	METSIM	Adipose	TPM2	0.12	0.13	lasso	5	0.14	1.1e-19	8.0	-7.2	6.4e-13	-0.99	0.00	1.00	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GBA2	0.05	0.05	blup	44	0.05	3.7e-06	-6.5	-7.2	8.2e-13	-0.44	0.87	0.09	FALSE
39	The Cancer Genome Atlas	Stomach Adenocarcinoma	GBA2	0.04	0.03	blup	44	0.02	1.0e-02	-5.3	-7.2	9.0e-13	-0.48	0.07	0.06	FALSE
32	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TPM2	0.11	0.08	enet	6	0.11	1.0e-06	7.8	-7.1	1.2e-12	-0.85	0.01	0.98	FALSE
41	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SPAG8	0.18	0.07	blup	47	0.09	1.7e-03	5.9	-6.9	6.0e-12	-0.54	0.02	0.25	FALSE
3	GTEx	Artery Aorta	SPAG8	0.11	0.10	lasso	7	0.06	2.0e-04	6.5	-6.8	1.1e-11	-0.74	0.08	0.90	FALSE
12	GTEx	Liver	NPR2	0.18	0.04	lasso	3	0.02	1.1e-01	6.7	-6.7	1.9e-11	-0.69	0.10	0.40	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	TPM2	0.11	0.16	lasso	5	0.17	3.5e-19	7.8	-6.7	2.1e-11	-0.96	0.01	0.99	FALSE
1	GTEx	Adrenal Gland	TPM2	0.29	0.22	lasso	5	0.25	1.8e-09	8.0	-6.6	4.0e-11	-0.96	0.00	1.00	FALSE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C9orf128	0.02	0.01	blup	50	0.01	2.3e-02	6.1	-6.5	7.6e-11	-0.60	0.04	0.77	FALSE
8	GTEx	Brain Hippocampus	TMEM8B	0.27	0.14	enet	15	0.14	4.4e-04	8.0	-6.2	4.7e-10	-0.81	0.02	0.86	FALSE
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	C9orf128	0.04	0.06	lasso	2	0.05	2.8e-04	6.2	-6.2	4.8e-10	-0.70	0.02	0.80	FALSE
10	GTEx	Breast Mammary Tissue (Female)	OR13E1P	0.06	0.05	lasso	2	0.01	1.4e-01	6.1	-6.1	9.5e-10	-0.59	0.05	0.12	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	C9orf128	0.14	0.15	blup	50	0.16	1.4e-32	6.2	-6.1	1.3e-09	-0.60	0.08	0.92	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	C9orf128	0.11	0.18	lasso	2	0.16	3.7e-16	6.1	-6.1	1.3e-09	-0.57	0.04	0.96	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	C9orf128	0.12	0.19	lasso	1	0.20	8.5e-19	6.1	-6.1	1.3e-09	-0.57	0.12	0.88	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM8B	0.04	0.02	blup	58	0.05	1.5e-05	6.4	6.0	1.7e-09	0.50	0.02	0.98	FALSE
4	GTEx	Artery Tibial	NPR2	0.15	0.03	enet	17	0.13	3.6e-10	0.5	5.9	3.6e-09	0.65	0.02	0.98	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	RP11-112J3.16	0.11	0.12	bslmm	410	0.11	1.5e-13	6.4	-5.9	4.0e-09	-0.60	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Lung Adenocarcinoma	C9orf128	0.07	0.07	lasso	2	0.07	1.6e-08	6.2	-5.8	6.7e-09	-0.55	0.05	0.95	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	ARHGEF39	0.28	0.00	enet	10	0.01	1.0e-01	4.4	-5.8	7.3e-09	-0.48	0.05	0.33	FALSE
19	GTEx	Whole Blood	GBA2	0.10	0.07	lasso	4	0.04	5.4e-05	-5.2	-5.6	1.7e-08	-0.20	0.99	0.00	FALSE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	C9orf128	0.07	0.03	blup	50	0.06	2.3e-04	6.1	-5.5	3.5e-08	-0.61	0.02	0.91	FALSE
7	GTEx	Brain Cerebellum	RMRP	0.27	0.00	enet	15	0.02	7.9e-02	1.2	5.3	1.2e-07	0.25	0.06	0.10	FALSE
15	GTEx	Nerve Tibial	GBA2	0.11	0.11	lasso	1	0.09	3.4e-07	-5.3	5.3	1.3e-07	0.19	0.98	0.01	FALSE
21	NTR	Blood	RGP1	0.03	0.03	lasso	1	0.02	2.1e-08	-5.3	5.3	1.3e-07	0.18	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	GBA2	0.07	0.08	lasso	4	0.07	6.4e-05	-5.3	-5.3	1.3e-07	-0.18	0.27	0.04	FALSE
2	GTEx	Artery Aorta	GBA2	0.15	0.10	lasso	6	0.07	9.8e-05	-5.3	5.3	1.4e-07	0.17	0.67	0.07	FALSE
29	The Cancer Genome Atlas	Esophageal Carcinoma	GBA2	0.11	0.10	lasso	1	0.08	1.8e-03	-5.2	-5.2	1.7e-07	-0.19	0.05	0.16	FALSE
13	GTEx	Muscle Skeletal	GBA2	0.15	0.11	lasso	5	0.08	1.4e-08	-5.2	-5.1	2.7e-07	-0.16	1.00	0.00	FALSE
17	GTEx	Thyroid	RP11-112J3.16	0.26	0.13	lasso	7	0.13	1.9e-10	6.4	-5.1	2.9e-07	-0.59	0.99	0.01	FALSE
18	GTEx	Vagina	TMEM8B	0.30	0.04	enet	31	0.04	4.5e-02	6.0	-5.1	2.9e-07	-0.43	0.06	0.10	FALSE